

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 7.35435310 |
| 2 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 7.35435310 |
| 3 | homocysteine metabolic process (GO:0050667) | 6.57171630 |
| 4 | proteasome assembly (GO:0043248) | 6.53609020 |
| 5 | purine nucleotide salvage (GO:0032261) | 6.38045272 |
| 6 | regulation of plasminogen activation (GO:0010755) | 6.26045045 |
| 7 | folic acid-containing compound biosynthetic process (GO:0009396) | 6.19569157 |
| 8 | positive regulation of endothelial cell differentiation (GO:0045603) | 5.75920528 |
| 9 | adenosine metabolic process (GO:0046085) | 5.73395389 |
| 10 | sulfur amino acid catabolic process (GO:0000098) | 5.49725098 |
| 11 | galactose catabolic process (GO:0019388) | 5.15833228 |
| 12 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.89668211 |
| 13 | galactose metabolic process (GO:0006012) | 4.65479019 |
| 14 | cysteine metabolic process (GO:0006534) | 4.58195178 |
| 15 | microtubule nucleation (GO:0007020) | 4.55028984 |
| 16 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 4.45796636 |
| 17 | negative regulation of catenin import into nucleus (GO:0035414) | 4.34093452 |
| 18 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 4.29632915 |
| 19 | platelet dense granule organization (GO:0060155) | 4.26707646 |
| 20 | alternative mRNA splicing, via spliceosome (GO:0000380) | 4.20597575 |
| 21 | white fat cell differentiation (GO:0050872) | 4.11722915 |
| 22 | regulation of endothelial cell differentiation (GO:0045601) | 4.11281212 |
| 23 | pteridine-containing compound biosynthetic process (GO:0042559) | 4.09690275 |
| 24 | desmosome organization (GO:0002934) | 4.06544010 |
| 25 | protein maturation by protein folding (GO:0022417) | 4.02319341 |
| 26 | response to gravity (GO:0009629) | 4.00300895 |
| 27 | IMP biosynthetic process (GO:0006188) | 3.95644491 |
| 28 | L-serine metabolic process (GO:0006563) | 3.88683879 |
| 29 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.86688817 |
| 30 | NADH dehydrogenase complex assembly (GO:0010257) | 3.86688817 |
| 31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.86688817 |
| 32 | negative regulation of DNA biosynthetic process (GO:2000279) | 3.83110598 |
| 33 | muscle atrophy (GO:0014889) | 3.70365637 |
| 34 | nucleoside transmembrane transport (GO:1901642) | 3.69185004 |
| 35 | polyamine biosynthetic process (GO:0006596) | 3.63286852 |
| 36 | mitochondrial RNA metabolic process (GO:0000959) | 3.60362272 |
| 37 | cell migration involved in heart development (GO:0060973) | 3.54713167 |
| 38 | nucleotide salvage (GO:0043173) | 3.52389235 |
| 39 | regulation of tight junction assembly (GO:2000810) | 3.49980921 |
| 40 | COPII vesicle coating (GO:0048208) | 3.42398366 |
| 41 | IMP metabolic process (GO:0046040) | 3.38720992 |
| 42 | regulation of gonadotropin secretion (GO:0032276) | 3.38000357 |
| 43 | cytidine catabolic process (GO:0006216) | 3.33985352 |
| 44 | cytidine deamination (GO:0009972) | 3.33985352 |
| 45 | cytidine metabolic process (GO:0046087) | 3.33985352 |
| 46 | DNA deamination (GO:0045006) | 3.32401397 |
| 47 | negative regulation of blood vessel endothelial cell migration (GO:0043537) | 3.32379557 |
| 48 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.30063828 |
| 49 | response to lipoprotein particle (GO:0055094) | 3.26013886 |
| 50 | inner ear receptor cell development (GO:0060119) | 3.21831317 |
| 51 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.21735213 |
| 52 | GTP biosynthetic process (GO:0006183) | 3.18961688 |
| 53 | regulation of sequestering of triglyceride (GO:0010889) | 3.15168965 |
| 54 | ribosome biogenesis (GO:0042254) | 3.14195492 |
| 55 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.13782874 |
| 56 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.12638381 |
| 57 | purine-containing compound salvage (GO:0043101) | 3.06173832 |
| 58 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 3.03130283 |
| 59 | serine family amino acid biosynthetic process (GO:0009070) | 3.02157304 |
| 60 | skeletal muscle tissue regeneration (GO:0043403) | 3.01756001 |
| 61 | negative regulation of Ras GTPase activity (GO:0034261) | 2.98389231 |
| 62 | rRNA modification (GO:0000154) | 2.98252462 |
| 63 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.95973858 |
| 64 | rRNA methylation (GO:0031167) | 2.95382894 |
| 65 | protein complex biogenesis (GO:0070271) | 2.93528452 |
| 66 | 4-hydroxyproline metabolic process (GO:0019471) | 2.92025612 |
| 67 | negative regulation of stem cell proliferation (GO:2000647) | 2.91776439 |
| 68 | tRNA modification (GO:0006400) | 2.89335300 |
| 69 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.88907205 |
| 70 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.88861090 |
| 71 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.87203808 |
| 72 | regulation of metalloenzyme activity (GO:0048552) | 2.84506862 |
| 73 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.83362690 |
| 74 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.83173838 |
| 75 | polyamine metabolic process (GO:0006595) | 2.81808159 |
| 76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.79363308 |
| 77 | UTP biosynthetic process (GO:0006228) | 2.78553900 |
| 78 | cellular response to zinc ion (GO:0071294) | 2.75334074 |
| 79 | cochlea development (GO:0090102) | 2.74317301 |
| 80 | COPI coating of Golgi vesicle (GO:0048205) | 2.74222083 |
| 81 | Golgi transport vesicle coating (GO:0048200) | 2.74222083 |
| 82 | negative regulation by host of viral transcription (GO:0043922) | 2.72687817 |
| 83 | establishment of viral latency (GO:0019043) | 2.72672660 |
| 84 | protein-chromophore linkage (GO:0018298) | 2.72262798 |
| 85 | positive regulation of actin filament depolymerization (GO:0030836) | 2.71018796 |
| 86 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.70622452 |
| 87 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.70622452 |
| 88 | sequestering of actin monomers (GO:0042989) | 2.70273526 |
| 89 | organic cation transport (GO:0015695) | 2.70163348 |
| 90 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.69513080 |
| 91 | phosphatidylglycerol biosynthetic process (GO:0006655) | 2.68850687 |
| 92 | extracellular fibril organization (GO:0043206) | 2.67152787 |
| 93 | protein-cofactor linkage (GO:0018065) | 2.66813565 |
| 94 | mitochondrial calcium ion transport (GO:0006851) | 2.66713377 |
| 95 | histone arginine methylation (GO:0034969) | 2.66143647 |
| 96 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.65887543 |
| 97 | tetrahydrofolate metabolic process (GO:0046653) | 2.65748383 |
| 98 | folic acid-containing compound metabolic process (GO:0006760) | 2.65169862 |
| 99 | facial nerve structural organization (GO:0021612) | 2.64692342 |
| 100 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.64139119 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.10413692 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.80043467 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.61791582 |
| 4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.27212375 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.07508359 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.96680921 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.85033072 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.38212531 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.30178815 |
| 10 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.30137078 |
| 11 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.27225263 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.22356078 |
| 13 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.20635468 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.19109561 |
| 15 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.09711978 |
| 16 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.09011519 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 10.5878960 |
| 18 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.99392574 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.97125443 |
| 20 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.83100380 |
| 21 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.79708261 |
| 22 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.77986545 |
| 23 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.76887351 |
| 24 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.76064813 |
| 25 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.70079322 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69416088 |
| 27 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69324946 |
| 28 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.68945933 |
| 29 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.67912157 |
| 30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.66225879 |
| 31 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.66080262 |
| 32 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.61808269 |
| 33 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.60869212 |
| 34 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.59767034 |
| 35 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.59276222 |
| 36 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55485716 |
| 37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.51865595 |
| 38 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.47680341 |
| 39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.46651707 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.45663876 |
| 41 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.45629795 |
| 42 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.45582587 |
| 43 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.45272809 |
| 44 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44146652 |
| 45 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.43758035 |
| 46 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.43079936 |
| 47 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.41685321 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.38638932 |
| 49 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.35595072 |
| 50 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.34434406 |
| 51 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.30442998 |
| 52 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.30392358 |
| 53 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 1.29619270 |
| 54 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.25961626 |
| 55 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.25827776 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18701569 |
| 57 | EOMES_21245162_ChIP-Seq_HESCs_Human | 1.17627751 |
| 58 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.13343984 |
| 59 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.12404403 |
| 60 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.10488491 |
| 61 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.08930305 |
| 62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06157108 |
| 63 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.03114724 |
| 64 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.02266700 |
| 65 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.01337620 |
| 66 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.99314426 |
| 67 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.99022363 |
| 68 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.97991078 |
| 69 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.97880218 |
| 70 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97638582 |
| 71 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.94772873 |
| 72 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.93839255 |
| 73 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.93823799 |
| 74 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.92686178 |
| 75 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.92089011 |
| 76 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.91906413 |
| 77 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.91797184 |
| 78 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.90854374 |
| 79 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88763936 |
| 80 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.87828937 |
| 81 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.87799468 |
| 82 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.85498968 |
| 83 | ATF3_27146783_Chip-Seq_COLON_Human | 0.85079109 |
| 84 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.84928707 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.84899375 |
| 86 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.84554203 |
| 87 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83606379 |
| 88 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.81688498 |
| 89 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.81174711 |
| 90 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.80633207 |
| 91 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.80192315 |
| 92 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.80099778 |
| 93 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.79495402 |
| 94 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.79077574 |
| 95 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.78269731 |
| 96 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.78263264 |
| 97 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.77758200 |
| 98 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.77119787 |
| 99 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.75987145 |
| 100 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.74914501 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003705_abnormal_hypodermis_morpholog | 4.62409691 |
| 2 | MP0000749_muscle_degeneration | 3.58399109 |
| 3 | MP0001661_extended_life_span | 3.53721834 |
| 4 | MP0005670_abnormal_white_adipose | 3.42479914 |
| 5 | MP0005646_abnormal_pituitary_gland | 3.32158829 |
| 6 | MP0005360_urolithiasis | 3.30061059 |
| 7 | MP0005367_renal/urinary_system_phenotyp | 2.88400101 |
| 8 | MP0000516_abnormal_urinary_system | 2.88400101 |
| 9 | MP0000013_abnormal_adipose_tissue | 2.77942400 |
| 10 | MP0006054_spinal_hemorrhage | 2.49910681 |
| 11 | MP0002736_abnormal_nociception_after | 2.47046089 |
| 12 | MP0000747_muscle_weakness | 2.41194032 |
| 13 | MP0003183_abnormal_peptide_metabolism | 2.36204463 |
| 14 | MP0000750_abnormal_muscle_regeneration | 2.30869737 |
| 15 | MP0003186_abnormal_redox_activity | 2.23038129 |
| 16 | MP0001348_abnormal_lacrimal_gland | 2.21386512 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.16007176 |
| 18 | MP0000647_abnormal_sebaceous_gland | 2.05533880 |
| 19 | MP0003786_premature_aging | 1.99636365 |
| 20 | MP0000534_abnormal_ureter_morphology | 1.97781049 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.92236529 |
| 22 | MP0004147_increased_porphyrin_level | 1.83612842 |
| 23 | MP0000751_myopathy | 1.73645418 |
| 24 | MP0000003_abnormal_adipose_tissue | 1.69898412 |
| 25 | MP0002269_muscular_atrophy | 1.68984948 |
| 26 | MP0001542_abnormal_bone_strength | 1.68339478 |
| 27 | MP0003566_abnormal_cell_adhesion | 1.66134334 |
| 28 | MP0004885_abnormal_endolymph | 1.64809770 |
| 29 | MP0008438_abnormal_cutaneous_collagen | 1.62486768 |
| 30 | MP0005165_increased_susceptibility_to | 1.62008037 |
| 31 | MP0009697_abnormal_copulation | 1.52234106 |
| 32 | MP0004272_abnormal_basement_membrane | 1.51523087 |
| 33 | MP0002938_white_spotting | 1.46282753 |
| 34 | MP0002295_abnormal_pulmonary_circulatio | 1.45918247 |
| 35 | MP0002089_abnormal_postnatal_growth/wei | 1.43202368 |
| 36 | MP0001879_abnormal_lymphatic_vessel | 1.41018400 |
| 37 | MP0000566_synostosis | 1.33909955 |
| 38 | MP0010030_abnormal_orbit_morphology | 1.33497280 |
| 39 | MP0002332_abnormal_exercise_endurance | 1.31178634 |
| 40 | MP0003942_abnormal_urinary_system | 1.29896442 |
| 41 | MP0000759_abnormal_skeletal_muscle | 1.28132658 |
| 42 | MP0010368_abnormal_lymphatic_system | 1.25969560 |
| 43 | MP0002138_abnormal_hepatobiliary_system | 1.24798651 |
| 44 | MP0003638_abnormal_response/metabolism_ | 1.23553693 |
| 45 | MP0008995_early_reproductive_senescence | 1.22647745 |
| 46 | MP0001756_abnormal_urination | 1.20005704 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.18107776 |
| 48 | MP0005257_abnormal_intraocular_pressure | 1.16622152 |
| 49 | MP0008872_abnormal_physiological_respon | 1.13468028 |
| 50 | MP0001243_abnormal_dermal_layer | 1.11460067 |
| 51 | MP0005083_abnormal_biliary_tract | 1.08154927 |
| 52 | MP0009333_abnormal_splenocyte_physiolog | 1.07295547 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.04789033 |
| 54 | MP0004957_abnormal_blastocyst_morpholog | 1.04327963 |
| 55 | MP0008007_abnormal_cellular_replicative | 1.00026099 |
| 56 | MP0003724_increased_susceptibility_to | 0.99867022 |
| 57 | MP0003693_abnormal_embryo_hatching | 0.99728871 |
| 58 | MP0002132_abnormal_respiratory_system | 0.99353680 |
| 59 | MP0002095_abnormal_skin_pigmentation | 0.98871541 |
| 60 | MP0001905_abnormal_dopamine_level | 0.98282675 |
| 61 | MP0002877_abnormal_melanocyte_morpholog | 0.96863167 |
| 62 | MP0004036_abnormal_muscle_relaxation | 0.95199443 |
| 63 | MP0004185_abnormal_adipocyte_glucose | 0.91319682 |
| 64 | MP0005197_abnormal_uvea_morphology | 0.90788028 |
| 65 | MP0003111_abnormal_nucleus_morphology | 0.90207675 |
| 66 | MP0004133_heterotaxia | 0.88587423 |
| 67 | MP0001340_abnormal_eyelid_morphology | 0.87405294 |
| 68 | MP0009780_abnormal_chondrocyte_physiolo | 0.86309682 |
| 69 | MP0001502_abnormal_circadian_rhythm | 0.84101389 |
| 70 | MP0002735_abnormal_chemical_nociception | 0.81612236 |
| 71 | MP0009053_abnormal_anal_canal | 0.80979883 |
| 72 | MP0008775_abnormal_heart_ventricle | 0.79251244 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.76705114 |
| 74 | MP0005623_abnormal_meninges_morphology | 0.75231884 |
| 75 | MP0005332_abnormal_amino_acid | 0.74796947 |
| 76 | MP0000733_abnormal_muscle_development | 0.69046988 |
| 77 | MP0004233_abnormal_muscle_weight | 0.65846963 |
| 78 | MP0000358_abnormal_cell_content/ | 0.65742951 |
| 79 | MP0003195_calcinosis | 0.65695116 |
| 80 | MP0002184_abnormal_innervation | 0.64930363 |
| 81 | MP0000762_abnormal_tongue_morphology | 0.63201799 |
| 82 | MP0002837_dystrophic_cardiac_calcinosis | 0.62340301 |
| 83 | MP0004134_abnormal_chest_morphology | 0.62320686 |
| 84 | MP0000613_abnormal_salivary_gland | 0.61012544 |
| 85 | MP0005620_abnormal_muscle_contractility | 0.60988798 |
| 86 | MP0002106_abnormal_muscle_physiology | 0.60500298 |
| 87 | MP0001849_ear_inflammation | 0.60284068 |
| 88 | MP0003315_abnormal_perineum_morphology | 0.59537703 |
| 89 | MP0004087_abnormal_muscle_fiber | 0.59369049 |
| 90 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.59211418 |
| 91 | MP0005084_abnormal_gallbladder_morpholo | 0.58741097 |
| 92 | MP0002148_abnormal_hypersensitivity_rea | 0.58533275 |
| 93 | MP0005595_abnormal_vascular_smooth | 0.58126831 |
| 94 | MP0001764_abnormal_homeostasis | 0.57870041 |
| 95 | MP0009643_abnormal_urine_homeostasis | 0.56712266 |
| 96 | MP0004043_abnormal_pH_regulation | 0.55887380 |
| 97 | MP0000049_abnormal_middle_ear | 0.55142793 |
| 98 | MP0005330_cardiomyopathy | 0.54754203 |
| 99 | MP0005369_muscle_phenotype | 0.54077775 |
| 100 | MP0000026_abnormal_inner_ear | 0.53032603 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 8.00424808 |
| 2 | Abnormality of alanine metabolism (HP:0010916) | 8.00424808 |
| 3 | Hyperalaninemia (HP:0003348) | 8.00424808 |
| 4 | Myocardial infarction (HP:0001658) | 5.11447277 |
| 5 | Constricted visual fields (HP:0001133) | 5.04484674 |
| 6 | Reduced subcutaneous adipose tissue (HP:0003758) | 4.58026218 |
| 7 | Abnormality of the fetal cardiovascular system (HP:0010948) | 4.54475644 |
| 8 | Abnormal umbilical cord blood vessels (HP:0011403) | 4.54475644 |
| 9 | Single umbilical artery (HP:0001195) | 4.54475644 |
| 10 | Conjugated hyperbilirubinemia (HP:0002908) | 4.29305595 |
| 11 | Spontaneous hematomas (HP:0007420) | 3.98006933 |
| 12 | Esophageal varix (HP:0002040) | 3.95518990 |
| 13 | Abnormality of the umbilical cord (HP:0010881) | 3.80479100 |
| 14 | Action tremor (HP:0002345) | 3.70244662 |
| 15 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.70197032 |
| 16 | Congenital sensorineural hearing impairment (HP:0008527) | 3.53062059 |
| 17 | Patchy hypopigmentation of hair (HP:0011365) | 3.42375252 |
| 18 | Hypoalphalipoproteinemia (HP:0003233) | 3.41391298 |
| 19 | White forelock (HP:0002211) | 3.27447990 |
| 20 | Conjunctival telangiectasia (HP:0000524) | 3.20998612 |
| 21 | Increased serum pyruvate (HP:0003542) | 3.08397770 |
| 22 | Petechiae (HP:0000967) | 2.97814429 |
| 23 | Anorexia (HP:0002039) | 2.97439783 |
| 24 | Abnormality of serum amino acid levels (HP:0003112) | 2.96108487 |
| 25 | Oligomenorrhea (HP:0000876) | 2.93952806 |
| 26 | Homocystinuria (HP:0002156) | 2.92460726 |
| 27 | Abnormality of homocysteine metabolism (HP:0010919) | 2.92460726 |
| 28 | Abnormalities of placenta or umbilical cord (HP:0001194) | 2.87840050 |
| 29 | Poor speech (HP:0002465) | 2.87529425 |
| 30 | Abnormality of glycolysis (HP:0004366) | 2.77790035 |
| 31 | Myopathic facies (HP:0002058) | 2.70410872 |
| 32 | Fatigue (HP:0012378) | 2.66443444 |
| 33 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.61493128 |
| 34 | Delayed CNS myelination (HP:0002188) | 2.59295981 |
| 35 | Heterochromia iridis (HP:0001100) | 2.57014899 |
| 36 | Large eyes (HP:0001090) | 2.55538848 |
| 37 | Toxemia of pregnancy (HP:0100603) | 2.55018649 |
| 38 | Generalized aminoaciduria (HP:0002909) | 2.53960026 |
| 39 | Decreased subcutaneous fat (HP:0001002) | 2.51055834 |
| 40 | Palpebral edema (HP:0100540) | 2.48361544 |
| 41 | Polygenic inheritance (HP:0010982) | 2.42136971 |
| 42 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.41390401 |
| 43 | Cholecystitis (HP:0001082) | 2.38604230 |
| 44 | Abnormal gallbladder physiology (HP:0012438) | 2.38604230 |
| 45 | Nausea (HP:0002018) | 2.33863572 |
| 46 | Adrenal hypoplasia (HP:0000835) | 2.29557102 |
| 47 | Menorrhagia (HP:0000132) | 2.26006650 |
| 48 | Mesomelia (HP:0003027) | 2.25628554 |
| 49 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.25301550 |
| 50 | Difficulty climbing stairs (HP:0003551) | 2.24940861 |
| 51 | Cortical visual impairment (HP:0100704) | 2.23177763 |
| 52 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.21867345 |
| 53 | Hyperlipoproteinemia (HP:0010980) | 2.16523219 |
| 54 | Wrist flexion contracture (HP:0001239) | 2.14517958 |
| 55 | Cavernous hemangioma (HP:0001048) | 2.13023722 |
| 56 | Ileus (HP:0002595) | 2.11008916 |
| 57 | Delayed gross motor development (HP:0002194) | 2.07096435 |
| 58 | Vascular calcification (HP:0004934) | 2.06670079 |
| 59 | Birth length less than 3rd percentile (HP:0003561) | 2.02372371 |
| 60 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.01865269 |
| 61 | Shoulder girdle muscle weakness (HP:0003547) | 2.01054362 |
| 62 | Hypergammaglobulinemia (HP:0010702) | 2.01005990 |
| 63 | Spinal muscular atrophy (HP:0007269) | 2.00720684 |
| 64 | Premature rupture of membranes (HP:0001788) | 2.00014866 |
| 65 | Abnormality of placental membranes (HP:0011409) | 1.99759853 |
| 66 | Amniotic constriction ring (HP:0009775) | 1.99759853 |
| 67 | Type I transferrin isoform profile (HP:0003642) | 1.98842395 |
| 68 | Increased purine levels (HP:0004368) | 1.98745508 |
| 69 | Hyperuricemia (HP:0002149) | 1.98745508 |
| 70 | Paralysis (HP:0003470) | 1.98042968 |
| 71 | Nemaline bodies (HP:0003798) | 1.93856550 |
| 72 | Postural tremor (HP:0002174) | 1.91021236 |
| 73 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.89991942 |
| 74 | Hypophosphatemic rickets (HP:0004912) | 1.89529016 |
| 75 | Purpura (HP:0000979) | 1.89133523 |
| 76 | Maternal diabetes (HP:0009800) | 1.86010679 |
| 77 | Exercise-induced muscle cramps (HP:0003710) | 1.84927463 |
| 78 | Cardiovascular calcification (HP:0011915) | 1.84760981 |
| 79 | Pelvic girdle muscle weakness (HP:0003749) | 1.84283091 |
| 80 | Stenosis of the external auditory canal (HP:0000402) | 1.82963069 |
| 81 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.81160774 |
| 82 | Autoimmune hemolytic anemia (HP:0001890) | 1.78888105 |
| 83 | Biconcave vertebral bodies (HP:0004586) | 1.78335135 |
| 84 | Short tibia (HP:0005736) | 1.73875938 |
| 85 | Median cleft lip (HP:0000161) | 1.73556727 |
| 86 | Metabolic acidosis (HP:0001942) | 1.73111335 |
| 87 | Methylmalonic aciduria (HP:0012120) | 1.72741441 |
| 88 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.70972635 |
| 89 | Reduced antithrombin III activity (HP:0001976) | 1.70382332 |
| 90 | Ectopic anus (HP:0004397) | 1.69900062 |
| 91 | Fibular aplasia (HP:0002990) | 1.67245980 |
| 92 | Abnormality of the renal collecting system (HP:0004742) | 1.66645415 |
| 93 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.65207010 |
| 94 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.65207010 |
| 95 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.62332990 |
| 96 | Hypoplastic left heart (HP:0004383) | 1.60921790 |
| 97 | Supernumerary spleens (HP:0009799) | 1.60345643 |
| 98 | Insulin resistance (HP:0000855) | 1.59151844 |
| 99 | Myoglobinuria (HP:0002913) | 1.58661802 |
| 100 | Duplicated collecting system (HP:0000081) | 1.58260377 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LMTK2 | 4.42990499 |
| 2 | BUB1 | 4.12070182 |
| 3 | VRK2 | 3.91878007 |
| 4 | TESK2 | 3.49130129 |
| 5 | MAP3K3 | 2.98837396 |
| 6 | TESK1 | 2.84368183 |
| 7 | PHKG2 | 2.61510578 |
| 8 | PHKG1 | 2.61510578 |
| 9 | LIMK1 | 2.48484510 |
| 10 | FER | 2.37224642 |
| 11 | MST4 | 2.32872397 |
| 12 | NME2 | 2.31584574 |
| 13 | MAP2K3 | 2.30202124 |
| 14 | PAK4 | 2.25283899 |
| 15 | FES | 2.23628670 |
| 16 | CCNB1 | 2.19812089 |
| 17 | JAK3 | 2.17472153 |
| 18 | CDK9 | 2.01262211 |
| 19 | EPHB2 | 1.99483856 |
| 20 | KDR | 1.99420243 |
| 21 | PLK2 | 1.84278991 |
| 22 | ARAF | 1.64352091 |
| 23 | AURKA | 1.62673395 |
| 24 | FGR | 1.60166429 |
| 25 | VRK1 | 1.55164381 |
| 26 | MAP2K7 | 1.53726544 |
| 27 | EPHA2 | 1.48635856 |
| 28 | STK16 | 1.47345530 |
| 29 | ACVR1B | 1.38362242 |
| 30 | MYLK | 1.38239772 |
| 31 | SMG1 | 1.29951488 |
| 32 | DAPK1 | 1.09747925 |
| 33 | PIM2 | 1.04813139 |
| 34 | ILK | 1.04523270 |
| 35 | BCKDK | 1.04103758 |
| 36 | SGK494 | 1.03808003 |
| 37 | SGK223 | 1.03808003 |
| 38 | PBK | 0.95827484 |
| 39 | SRPK1 | 0.93554310 |
| 40 | PLK3 | 0.92937183 |
| 41 | TIE1 | 0.91757305 |
| 42 | MAP3K12 | 0.90870791 |
| 43 | EIF2AK1 | 0.88148705 |
| 44 | PAK1 | 0.86666367 |
| 45 | ABL2 | 0.85873844 |
| 46 | NTRK2 | 0.81634632 |
| 47 | PRKCE | 0.80730924 |
| 48 | AKT3 | 0.78933682 |
| 49 | GRK5 | 0.78459470 |
| 50 | DYRK2 | 0.78439285 |
| 51 | CSNK1A1 | 0.78117027 |
| 52 | MOS | 0.77945007 |
| 53 | ADRBK1 | 0.77728884 |
| 54 | STK10 | 0.77145212 |
| 55 | PRKCI | 0.76236127 |
| 56 | PRKD3 | 0.76223552 |
| 57 | CSNK1G3 | 0.75992339 |
| 58 | TAF1 | 0.75121325 |
| 59 | RPS6KB2 | 0.74838864 |
| 60 | SGK2 | 0.72030125 |
| 61 | ERBB3 | 0.71515986 |
| 62 | MST1R | 0.70836399 |
| 63 | DAPK3 | 0.66696575 |
| 64 | NUAK1 | 0.65831410 |
| 65 | BRAF | 0.61198906 |
| 66 | CAMK2G | 0.57477534 |
| 67 | CSNK1G1 | 0.57398358 |
| 68 | BRSK1 | 0.53879620 |
| 69 | MAPKAPK3 | 0.53257417 |
| 70 | ERBB4 | 0.52758809 |
| 71 | MAP3K11 | 0.52344551 |
| 72 | CSNK1A1L | 0.50214237 |
| 73 | AKT2 | 0.48600938 |
| 74 | MAP2K1 | 0.47358452 |
| 75 | SGK3 | 0.46935137 |
| 76 | MAP4K2 | 0.45042080 |
| 77 | CHEK2 | 0.44658247 |
| 78 | BMX | 0.43026288 |
| 79 | CSNK1G2 | 0.42863900 |
| 80 | CDK7 | 0.41459579 |
| 81 | PAK2 | 0.39411095 |
| 82 | TLK1 | 0.39231589 |
| 83 | FGFR1 | 0.39137629 |
| 84 | CAMKK2 | 0.36177299 |
| 85 | BCR | 0.33682380 |
| 86 | PTK2B | 0.33532968 |
| 87 | IKBKB | 0.32462415 |
| 88 | PRKCQ | 0.32430297 |
| 89 | PRKCD | 0.32045624 |
| 90 | HIPK2 | 0.31819629 |
| 91 | PRKD1 | 0.31776074 |
| 92 | CAMK1 | 0.30374790 |
| 93 | NEK9 | 0.30109468 |
| 94 | GSK3A | 0.29910703 |
| 95 | PTK6 | 0.26778893 |
| 96 | PRKCA | 0.26724568 |
| 97 | CSNK2A1 | 0.26617181 |
| 98 | CAMK2D | 0.26011074 |
| 99 | ROCK2 | 0.24699750 |
| 100 | PTK2 | 0.23984009 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.46799079 |
| 2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.96456554 |
| 3 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 3.18672048 |
| 4 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.06676913 |
| 5 | Galactose metabolism_Homo sapiens_hsa00052 | 2.97106024 |
| 6 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.83633338 |
| 7 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.80174965 |
| 8 | Sulfur relay system_Homo sapiens_hsa04122 | 2.71476059 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.68694885 |
| 10 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.29158045 |
| 11 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.22098067 |
| 12 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.17091605 |
| 13 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.98643938 |
| 14 | Carbon metabolism_Homo sapiens_hsa01200 | 1.89528751 |
| 15 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.86665652 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.84715455 |
| 17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.73710482 |
| 18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.68389141 |
| 19 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.67681345 |
| 20 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.52037040 |
| 21 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.51789957 |
| 22 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.48046273 |
| 23 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.45524228 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.39688170 |
| 25 | Base excision repair_Homo sapiens_hsa03410 | 1.33715681 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.31354622 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.30549432 |
| 28 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.29965452 |
| 29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.22190719 |
| 30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21726463 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08883975 |
| 32 | GABAergic synapse_Homo sapiens_hsa04727 | 1.08652856 |
| 33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.07584177 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.06454398 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.06420887 |
| 36 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.06312940 |
| 37 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.05015721 |
| 38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04926769 |
| 39 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.03951085 |
| 40 | Huntingtons disease_Homo sapiens_hsa05016 | 1.00716286 |
| 41 | Alzheimers disease_Homo sapiens_hsa05010 | 0.98821761 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.98524675 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.97846753 |
| 44 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97644681 |
| 45 | Protein export_Homo sapiens_hsa03060 | 0.94553309 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.90293881 |
| 47 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.86705481 |
| 48 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.82109765 |
| 49 | Alcoholism_Homo sapiens_hsa05034 | 0.81714184 |
| 50 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.79166046 |
| 51 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.78995483 |
| 52 | Spliceosome_Homo sapiens_hsa03040 | 0.75574625 |
| 53 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74437632 |
| 54 | Homologous recombination_Homo sapiens_hsa03440 | 0.72334159 |
| 55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71919756 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.70669735 |
| 57 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.69089066 |
| 58 | RNA transport_Homo sapiens_hsa03013 | 0.62949438 |
| 59 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.62288027 |
| 60 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61672095 |
| 61 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.59327862 |
| 62 | Thyroid cancer_Homo sapiens_hsa05216 | 0.58900398 |
| 63 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.56250828 |
| 64 | Salmonella infection_Homo sapiens_hsa05132 | 0.55469815 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55214785 |
| 66 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.54568645 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.52807901 |
| 68 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.51909433 |
| 69 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.51743189 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50501993 |
| 71 | RNA polymerase_Homo sapiens_hsa03020 | 0.49918373 |
| 72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.49084201 |
| 73 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.48627490 |
| 74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.48320259 |
| 75 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.45779469 |
| 76 | RNA degradation_Homo sapiens_hsa03018 | 0.44883905 |
| 77 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.43818656 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.41103492 |
| 79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.40624507 |
| 80 | Purine metabolism_Homo sapiens_hsa00230 | 0.40326159 |
| 81 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.40160808 |
| 82 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.37224489 |
| 83 | Lysosome_Homo sapiens_hsa04142 | 0.33865450 |
| 84 | Tight junction_Homo sapiens_hsa04530 | 0.33311966 |
| 85 | Endocytosis_Homo sapiens_hsa04144 | 0.30978725 |
| 86 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.27352694 |
| 87 | Apoptosis_Homo sapiens_hsa04210 | 0.26113452 |
| 88 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.25786778 |
| 89 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.24893133 |
| 90 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.23350100 |
| 91 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.22504642 |
| 92 | Mineral absorption_Homo sapiens_hsa04978 | 0.20802366 |
| 93 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.19841386 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.19000391 |
| 95 | Salivary secretion_Homo sapiens_hsa04970 | 0.18090815 |
| 96 | Adherens junction_Homo sapiens_hsa04520 | 0.18011454 |
| 97 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.15411637 |
| 98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.14655540 |
| 99 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.14274759 |
| 100 | Shigellosis_Homo sapiens_hsa05131 | 0.13477197 |

