PLEKHB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)8.17331216
2axon ensheathment in central nervous system (GO:0032291)8.17331216
3synaptic vesicle docking involved in exocytosis (GO:0016081)7.38170424
4axon ensheathment (GO:0008366)4.76004567
5ensheathment of neurons (GO:0007272)4.76004567
6myelination (GO:0042552)4.75780176
7L-amino acid import (GO:0043092)4.68646908
8postsynaptic membrane organization (GO:0001941)4.59562683
9fatty acid elongation (GO:0030497)4.54822061
10synaptic vesicle maturation (GO:0016188)4.52400827
11cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.48362968
12positive regulation of synapse maturation (GO:0090129)4.43993729
13exploration behavior (GO:0035640)4.22916755
14cellular sodium ion homeostasis (GO:0006883)4.10201626
15myelin maintenance (GO:0043217)3.99545038
16regulation of ARF protein signal transduction (GO:0032012)3.99190484
17regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.93917121
18negative regulation of synaptic transmission, GABAergic (GO:0032229)3.93664731
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.93365096
20neurotransmitter-gated ion channel clustering (GO:0072578)3.91507615
21regulation of neurotransmitter levels (GO:0001505)3.90696085
22glycine transport (GO:0015816)3.89240897
23cell communication by electrical coupling (GO:0010644)3.87670222
24neuronal action potential propagation (GO:0019227)3.87504419
25positive regulation of dendritic spine development (GO:0060999)3.81566743
26regulation of synaptic plasticity (GO:0048167)3.79599958
27regulation of short-term neuronal synaptic plasticity (GO:0048172)3.76748992
28eye photoreceptor cell differentiation (GO:0001754)3.76122183
29photoreceptor cell differentiation (GO:0046530)3.76122183
30regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.64880368
31amino acid import (GO:0043090)3.62728944
32long-chain fatty acid biosynthetic process (GO:0042759)3.61981437
33regulation of synaptic vesicle exocytosis (GO:2000300)3.59677883
34locomotory exploration behavior (GO:0035641)3.59092317
35negative regulation of neurotransmitter transport (GO:0051589)3.57796076
36positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.55784417
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.55541794
38adult walking behavior (GO:0007628)3.50492642
39synaptic vesicle exocytosis (GO:0016079)3.50346886
40regulation of synapse maturation (GO:0090128)3.46516714
41synaptic vesicle endocytosis (GO:0048488)3.46057193
42cellular potassium ion homeostasis (GO:0030007)3.44511854
43glutamate secretion (GO:0014047)3.39955823
44transmission of nerve impulse (GO:0019226)3.36917651
45negative regulation of neurotransmitter secretion (GO:0046929)3.35203503
46response to methylmercury (GO:0051597)3.34950652
47neuron cell-cell adhesion (GO:0007158)3.28239547
48establishment of mitochondrion localization (GO:0051654)3.25710724
49regulation of postsynaptic membrane potential (GO:0060078)3.25354339
50cerebellar Purkinje cell differentiation (GO:0021702)3.24189864
51potassium ion import (GO:0010107)3.24068879
52oligodendrocyte differentiation (GO:0048709)3.22563860
53cytoskeletal anchoring at plasma membrane (GO:0007016)3.21641912
54gamma-aminobutyric acid transport (GO:0015812)3.19832214
55regulation of synaptic vesicle transport (GO:1902803)3.19314710
56regulation of dendritic spine morphogenesis (GO:0061001)3.16231649
57regulation of dendritic spine development (GO:0060998)3.15677589
58negative regulation of protein localization to cell surface (GO:2000009)3.15668160
59gamma-aminobutyric acid signaling pathway (GO:0007214)3.15407140
60peptidyl-tyrosine autophosphorylation (GO:0038083)3.13310563
61regulation of neuronal synaptic plasticity (GO:0048168)3.11762273
62potassium ion homeostasis (GO:0055075)3.11645772
63positive regulation of neurotransmitter transport (GO:0051590)3.11295925
64regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11237477
65negative regulation of dendrite morphogenesis (GO:0050774)3.09899541
66regulation of vesicle fusion (GO:0031338)3.09879311
67presynaptic membrane organization (GO:0097090)3.07594357
68negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.07434262
69neuronal ion channel clustering (GO:0045161)3.07069987
70neurotransmitter uptake (GO:0001504)3.07022346
71apical protein localization (GO:0045176)3.05866257
72cerebellar Purkinje cell layer development (GO:0021680)3.05827966
73positive regulation of neurotransmitter secretion (GO:0001956)3.05295532
74regulation of female receptivity (GO:0045924)3.05270244
75regulation of synaptic transmission (GO:0050804)3.04975819
76regulation of voltage-gated calcium channel activity (GO:1901385)3.04306138
77neuromuscular process controlling posture (GO:0050884)3.03645929
78sodium ion export (GO:0071436)2.98882365
79membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.98510607
80mating behavior (GO:0007617)2.95334202
81positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.95324473
82ionotropic glutamate receptor signaling pathway (GO:0035235)2.95291538
83negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.95147239
84negative regulation of inclusion body assembly (GO:0090084)2.94805048
85astrocyte differentiation (GO:0048708)2.94777696
86activation of protein kinase A activity (GO:0034199)2.93828812
87dendritic spine morphogenesis (GO:0060997)2.93106213
88protein localization to synapse (GO:0035418)2.89030829
89positive regulation of dendrite development (GO:1900006)2.88662899
90cell communication involved in cardiac conduction (GO:0086065)2.88500109
91regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.86848717
92neurotransmitter secretion (GO:0007269)2.85799733
93regulation of rhodopsin mediated signaling pathway (GO:0022400)2.85522653
94asymmetric protein localization (GO:0008105)2.84699608
95import into cell (GO:0098657)2.84665937
96substantia nigra development (GO:0021762)2.84607183
97regulation of collateral sprouting (GO:0048670)2.83035286
98vocalization behavior (GO:0071625)2.81885711
99presynaptic membrane assembly (GO:0097105)2.81288155
100membrane hyperpolarization (GO:0060081)2.81264008
101rhodopsin mediated signaling pathway (GO:0016056)2.81080628
102layer formation in cerebral cortex (GO:0021819)2.80172892
103neurotransmitter transport (GO:0006836)2.79490546
104regulation of long-term neuronal synaptic plasticity (GO:0048169)2.78254144
105sensory perception of smell (GO:0007608)2.77391117
106neuron-neuron synaptic transmission (GO:0007270)2.76005695
107positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74050386
108creatine metabolic process (GO:0006600)2.71047575
109neuron recognition (GO:0008038)2.70636966
110synaptic transmission, glutamatergic (GO:0035249)2.68414863
111astrocyte development (GO:0014002)2.68135834
112dendrite morphogenesis (GO:0048813)2.67825824
113myelination in peripheral nervous system (GO:0022011)2.66152222
114peripheral nervous system axon ensheathment (GO:0032292)2.66152222
115regulation of neurotransmitter uptake (GO:0051580)2.65977392
116negative regulation of axonogenesis (GO:0050771)2.65248187
117positive regulation of potassium ion transport (GO:0043268)2.65007631
118glutamate receptor signaling pathway (GO:0007215)2.64251094
119long-term synaptic potentiation (GO:0060291)2.64223290
120glycerophospholipid catabolic process (GO:0046475)2.63487466
121membrane tubulation (GO:0097320)2.62518069
122behavioral response to cocaine (GO:0048148)2.61687762
123response to auditory stimulus (GO:0010996)2.60591028
124regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.60017861
125cerebellar granule cell differentiation (GO:0021707)2.58968254
126regulation of glutamate receptor signaling pathway (GO:1900449)2.57727010
127positive regulation of membrane potential (GO:0045838)2.56598639
128neuromuscular process controlling balance (GO:0050885)2.56113053
129nerve growth factor signaling pathway (GO:0038180)2.55393769
130auditory behavior (GO:0031223)2.55113162
131acidic amino acid transport (GO:0015800)2.54530717
132regulation of synapse structural plasticity (GO:0051823)2.54145919
133long-term memory (GO:0007616)2.53528653
134L-glutamate transport (GO:0015813)2.52383441
135regulation of neurotransmitter transport (GO:0051588)2.52262252
136neuron remodeling (GO:0016322)2.51888907
137regulation of neurotransmitter secretion (GO:0046928)2.51771904
138negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.51268011

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.10821684
2GBX2_23144817_ChIP-Seq_PC3_Human2.85388083
3THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.74852646
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.72719885
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.67577670
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.49910358
7DROSHA_22980978_ChIP-Seq_HELA_Human2.45313862
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.44857436
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.44857436
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.40125893
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.39477085
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.22587405
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.19662995
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.19458974
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.18636780
16SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16466928
17* RARB_27405468_Chip-Seq_BRAIN_Mouse2.16352150
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.14484508
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.08628710
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.02030987
21REST_21632747_ChIP-Seq_MESCs_Mouse1.98742484
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.94438497
23AR_21572438_ChIP-Seq_LNCaP_Human1.94398102
24SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.86169040
25RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.83258493
26* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.76353016
27REST_18959480_ChIP-ChIP_MESCs_Mouse1.69867828
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62170491
29EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.54332727
30OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47106532
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.45472431
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.44074119
33TAF15_26573619_Chip-Seq_HEK293_Human1.42045919
34* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.41403311
35VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.40944428
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40655723
37SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.39747523
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.37765702
39LXR_22292898_ChIP-Seq_THP-1_Human1.35050506
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.34006359
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.32812775
42TET1_21490601_ChIP-Seq_MESCs_Mouse1.30285917
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29026289
44RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27902077
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.26767676
46KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26759824
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.25949830
48EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.24997225
49* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24916351
50SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.24001282
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.23776928
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.23717775
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.22069160
54SMAD4_21799915_ChIP-Seq_A2780_Human1.21774980
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20979764
56RING1B_27294783_Chip-Seq_ESCs_Mouse1.19257862
57P53_22127205_ChIP-Seq_FIBROBLAST_Human1.18318152
58STAT3_23295773_ChIP-Seq_U87_Human1.16802944
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.15665360
60ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.15133130
61TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14337589
62CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14137278
63ZFP57_27257070_Chip-Seq_ESCs_Mouse1.14068699
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12765208
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.12199963
66CBX2_27304074_Chip-Seq_ESCs_Mouse1.11840139
67PIAS1_25552417_ChIP-Seq_VCAP_Human1.10855723
68* SMC4_20622854_ChIP-Seq_HELA_Human1.08476137
69OCT4_19829295_ChIP-Seq_ESCs_Human1.08017499
70P300_19829295_ChIP-Seq_ESCs_Human1.07890571
71PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.07841557
72ER_23166858_ChIP-Seq_MCF-7_Human1.07365491
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06559746
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05728326
75RING1B_27294783_Chip-Seq_NPCs_Mouse1.05208635
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03941586
77PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03107019
78DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02291850
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01654092
80GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00622478
81NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00191421
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00059286
83ARNT_22903824_ChIP-Seq_MCF-7_Human0.99261230
84AHR_22903824_ChIP-Seq_MCF-7_Human0.98698665
85KDM2B_26808549_Chip-Seq_K562_Human0.98697235
86* SOX2_21211035_ChIP-Seq_LN229_Gbm0.98696261
87STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97859512
88MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97581088
89NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96672085
90SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96002237
91ESR1_20079471_ChIP-ChIP_T-47D_Human0.95493384
92* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.95394105
93EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.95357210
94EP300_21415370_ChIP-Seq_HL-1_Mouse0.95077719
95AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95072076
96ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.94965749
97TCF4_23295773_ChIP-Seq_U87_Human0.94558548
98GATA1_26923725_Chip-Seq_HPCs_Mouse0.93832667
99AR_19668381_ChIP-Seq_PC3_Human0.93588901
100ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93271293
101BMI1_23680149_ChIP-Seq_NPCS_Mouse0.92887529
102LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92035963
103SMAD4_21741376_ChIP-Seq_HESCs_Human0.92002114
104CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.91172661
105SMAD4_21741376_ChIP-Seq_EPCs_Human0.91149819
106ESR2_21235772_ChIP-Seq_MCF-7_Human0.90990850
107TRIM28_21343339_ChIP-Seq_HEK293_Human0.90102211
108LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89334062
109KLF4_19829295_ChIP-Seq_ESCs_Human0.88969267
110PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.88734640
111* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88287527
112* PRDM14_20953172_ChIP-Seq_ESCs_Human0.87527830
113CREB1_26743006_Chip-Seq_LNCaP_Human0.86585657
114VDR_22108803_ChIP-Seq_LS180_Human0.86491390
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86119431
116POU3F2_20337985_ChIP-ChIP_501MEL_Human0.85930700
117TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.85816485
118WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.85582867
119* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.84968369
120* DPY_21335234_ChIP-Seq_ESCs_Mouse0.84903997
121CTCF_27219007_Chip-Seq_Bcells_Human0.83665599
122SMAD3_21741376_ChIP-Seq_ESCs_Human0.83628114
123KDM2B_26808549_Chip-Seq_DND41_Human0.82611233
124MYC_19915707_ChIP-ChIP_AK7_Human0.82122105
125CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81961096
126SMAD4_21741376_ChIP-Seq_ESCs_Human0.81199065
127TP53_23651856_ChIP-Seq_MEFs_Mouse0.81098942
128SMAD3_21741376_ChIP-Seq_HESCs_Human0.80956483
129RUNX2_22187159_ChIP-Seq_PCA_Human0.80823721
130SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80556807
131EGR1_19032775_ChIP-ChIP_M12_Human0.80422337
132NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.80230197
133NRF2_20460467_ChIP-Seq_MEFs_Mouse0.80230197
134SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77056176
135* P68_20966046_ChIP-Seq_HELA_Human0.76846656
136CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.75744426
137RUNX1_26923725_Chip-Seq_HPCs_Mouse0.75465931
138SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.75101587
139KDM2B_26808549_Chip-Seq_JURKAT_Human0.74440883
140BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74092200

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.28016966
2MP0003880_abnormal_central_pattern4.20703703
3MP0000920_abnormal_myelination3.67226803
4MP0004270_analgesia3.44709556
5MP0003635_abnormal_synaptic_transmissio3.05647387
6MP0002272_abnormal_nervous_system2.92744972
7MP0001486_abnormal_startle_reflex2.90701450
8MP0002064_seizures2.87884821
9MP0004885_abnormal_endolymph2.78244663
10MP0005423_abnormal_somatic_nervous2.74082446
11MP0005551_abnormal_eye_electrophysiolog2.71034053
12MP0003690_abnormal_glial_cell2.63645291
13MP0009745_abnormal_behavioral_response2.63123338
14MP0009046_muscle_twitch2.57629398
15MP0003329_amyloid_beta_deposits2.56574298
16MP0002822_catalepsy2.32620465
17MP0002063_abnormal_learning/memory/cond2.31918710
18MP0002734_abnormal_mechanical_nocicepti2.30901715
19MP0001984_abnormal_olfaction2.26916096
20MP0003634_abnormal_glial_cell2.10359746
21MP0002572_abnormal_emotion/affect_behav2.04595467
22MP0002229_neurodegeneration2.00541399
23MP0004142_abnormal_muscle_tone1.99075958
24MP0008569_lethality_at_weaning1.92324122
25MP0003950_abnormal_plasma_membrane1.91394620
26MP0004742_abnormal_vestibular_system1.90919080
27MP0000778_abnormal_nervous_system1.90708903
28MP0001485_abnormal_pinna_reflex1.84520779
29MP0001905_abnormal_dopamine_level1.84327816
30MP0001968_abnormal_touch/_nociception1.83299443
31MP0001529_abnormal_vocalization1.80010940
32MP0002882_abnormal_neuron_morphology1.70242914
33MP0002067_abnormal_sensory_capabilities1.68418767
34MP0001970_abnormal_pain_threshold1.66378694
35MP0003633_abnormal_nervous_system1.66157814
36MP0001440_abnormal_grooming_behavior1.63245940
37MP0005253_abnormal_eye_physiology1.58525896
38MP0000955_abnormal_spinal_cord1.57845649
39MP0003631_nervous_system_phenotype1.54919446
40MP0003632_abnormal_nervous_system1.51514604
41MP0006072_abnormal_retinal_apoptosis1.47394051
42MP0001501_abnormal_sleep_pattern1.46980341
43MP0002733_abnormal_thermal_nociception1.46362246
44MP0002066_abnormal_motor_capabilities/c1.42256864
45MP0005386_behavior/neurological_phenoty1.41320038
46MP0004924_abnormal_behavior1.41320038
47MP0003787_abnormal_imprinting1.38942538
48MP0001502_abnormal_circadian_rhythm1.37741210
49MP0004043_abnormal_pH_regulation1.37679947
50MP0005171_absent_coat_pigmentation1.36244832
51MP0003011_delayed_dark_adaptation1.36183239
52MP0005646_abnormal_pituitary_gland1.35813641
53MP0002752_abnormal_somatic_nervous1.34962302
54MP0003123_paternal_imprinting1.34159501
55MP0003136_yellow_coat_color1.33529062
56MP0002184_abnormal_innervation1.29358478
57MP0002557_abnormal_social/conspecific_i1.28248524
58MP0004811_abnormal_neuron_physiology1.23983859
59MP0005645_abnormal_hypothalamus_physiol1.23646788
60MP0000604_amyloidosis1.23504572
61MP0002736_abnormal_nociception_after1.23366365
62MP0005195_abnormal_posterior_eye1.22557578
63MP0001963_abnormal_hearing_physiology1.21009552
64MP0005623_abnormal_meninges_morphology1.16919665
65MP0005410_abnormal_fertilization1.15890785
66MP0002090_abnormal_vision1.15075334
67MP0004145_abnormal_muscle_electrophysio1.07339165
68MP0005409_darkened_coat_color1.06333098
69MP0001177_atelectasis1.05984573
70MP0001986_abnormal_taste_sensitivity1.04223802
71MP0002152_abnormal_brain_morphology1.03775248
72MP0003122_maternal_imprinting1.02069946
73MP0000747_muscle_weakness0.99601844
74MP0009780_abnormal_chondrocyte_physiolo0.98884830
75MP0002735_abnormal_chemical_nociception0.98680053
76MP0001299_abnormal_eye_distance/0.97879059
77MP0004858_abnormal_nervous_system0.97020535
78MP0003075_altered_response_to0.96254146
79MP0002909_abnormal_adrenal_gland0.95057564
80MP0002653_abnormal_ependyma_morphology0.94670758
81MP0000566_synostosis0.89562465
82MP0005499_abnormal_olfactory_system0.85921890
83MP0005394_taste/olfaction_phenotype0.85921890
84MP0010678_abnormal_skin_adnexa0.76746166
85MP0003172_abnormal_lysosome_physiology0.75480606
86MP0008874_decreased_physiological_sensi0.71052249
87MP0003879_abnormal_hair_cell0.70864049
88MP0006276_abnormal_autonomic_nervous0.70688059
89MP0000013_abnormal_adipose_tissue0.69785802
90MP0000026_abnormal_inner_ear0.69693678
91MP0005166_decreased_susceptibility_to0.69630121
92MP0005535_abnormal_body_temperature0.68703495
93MP0005167_abnormal_blood-brain_barrier0.67807241
94MP0000462_abnormal_digestive_system0.67735653
95MP0004147_increased_porphyrin_level0.67137988
96MP0002069_abnormal_eating/drinking_beha0.66298274
97MP0003137_abnormal_impulse_conducting0.65811870
98MP0002638_abnormal_pupillary_reflex0.65111960
99MP0005058_abnormal_lysosome_morphology0.64874480
100MP0000751_myopathy0.64086563
101MP0004130_abnormal_muscle_cell0.63746613
102MP0000579_abnormal_nail_morphology0.63260008
103MP0005391_vision/eye_phenotype0.62754008
104MP0000631_abnormal_neuroendocrine_gland0.61365181
105MP0008260_abnormal_autophagy0.61205811
106MP0000003_abnormal_adipose_tissue0.60344207
107MP0004134_abnormal_chest_morphology0.58995635
108MP0002089_abnormal_postnatal_growth/wei0.58341655
109MP0001348_abnormal_lacrimal_gland0.57876620
110MP0004085_abnormal_heartbeat0.55895232
111MP0001346_abnormal_lacrimal_gland0.55740539
112MP0001943_abnormal_respiration0.54172659
113MP0008872_abnormal_physiological_respon0.52784972
114MP0010769_abnormal_survival0.52552402
115MP0003183_abnormal_peptide_metabolism0.51962726
116MP0003956_abnormal_body_size0.48947121
117MP0010768_mortality/aging0.48606914
118MP0003283_abnormal_digestive_organ0.47706914
119MP0010770_preweaning_lethality0.46990115
120MP0002082_postnatal_lethality0.46990115
121MP0001731_abnormal_postnatal_growth0.46515355
122MP0000639_abnormal_adrenal_gland0.45736191
123MP0003861_abnormal_nervous_system0.45562689

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)5.22294027
2Myokymia (HP:0002411)5.17143114
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.63603299
4Degeneration of the lateral corticospinal tracts (HP:0002314)4.63603299
5Supranuclear gaze palsy (HP:0000605)4.54112923
6Peripheral hypomyelination (HP:0007182)4.28748512
7Obstructive sleep apnea (HP:0002870)4.03488265
8Focal motor seizures (HP:0011153)4.03364667
9Ankle clonus (HP:0011448)4.00936453
10Action tremor (HP:0002345)3.88638984
11Cerebral inclusion bodies (HP:0100314)3.88339582
12Abnormality of the corticospinal tract (HP:0002492)3.83407708
13Termporal pattern (HP:0011008)3.67919262
14Insidious onset (HP:0003587)3.67919262
15Intention tremor (HP:0002080)3.60651513
16Dysmetria (HP:0001310)3.54036090
17Onion bulb formation (HP:0003383)3.50131574
18Spastic gait (HP:0002064)3.45874951
19Hemiplegia (HP:0002301)3.40246379
20Papilledema (HP:0001085)3.35152304
21Tetraplegia (HP:0002445)3.25115166
22Annular pancreas (HP:0001734)3.21474285
23Focal seizures (HP:0007359)3.14450900
24Megalencephaly (HP:0001355)3.13865566
25Abolished electroretinogram (ERG) (HP:0000550)3.12400735
26Scanning speech (HP:0002168)3.10444252
27Abnormality of macular pigmentation (HP:0008002)2.99732162
28Abnormal auditory evoked potentials (HP:0006958)2.96327429
29Retinal dysplasia (HP:0007973)2.88999421
30Central scotoma (HP:0000603)2.87953590
31Congenital stationary night blindness (HP:0007642)2.86788696
32Cerebral hypomyelination (HP:0006808)2.83995179
33Akinesia (HP:0002304)2.83505860
34Dysdiadochokinesis (HP:0002075)2.76612268
35Urinary urgency (HP:0000012)2.71200741
36Sleep apnea (HP:0010535)2.71132086
37Atonic seizures (HP:0010819)2.71117635
38Delusions (HP:0000746)2.67791135
39Sensory axonal neuropathy (HP:0003390)2.66687361
40Bony spicule pigmentary retinopathy (HP:0007737)2.63044852
41Insomnia (HP:0100785)2.62483928
42Progressive cerebellar ataxia (HP:0002073)2.60985113
43Epileptic encephalopathy (HP:0200134)2.60822365
44Visual hallucinations (HP:0002367)2.58054841
45Lower limb muscle weakness (HP:0007340)2.57176493
46Aplasia involving bones of the extremities (HP:0009825)2.56644813
47Aplasia involving bones of the upper limbs (HP:0009823)2.56644813
48Aplasia of the phalanges of the hand (HP:0009802)2.56644813
49Postural instability (HP:0002172)2.54912871
50Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.54683394
51Segmental peripheral demyelination/remyelination (HP:0003481)2.54013941
52Bradykinesia (HP:0002067)2.53869895
53Pheochromocytoma (HP:0002666)2.53189052
54Slow saccadic eye movements (HP:0000514)2.52751184
55Status epilepticus (HP:0002133)2.45661349
56Apathy (HP:0000741)2.40840905
57Anxiety (HP:0000739)2.38633091
58Clonus (HP:0002169)2.37956330
59Alacrima (HP:0000522)2.35317942
60Torticollis (HP:0000473)2.34993648
61Abnormal ciliary motility (HP:0012262)2.34564084
62Urinary bladder sphincter dysfunction (HP:0002839)2.33030150
63Depression (HP:0000716)2.32907222
64Decreased central vision (HP:0007663)2.32117339
65Abnormal respiratory motile cilium physiology (HP:0012261)2.30955010
66Poor eye contact (HP:0000817)2.30155046
67Abnormal rod and cone electroretinograms (HP:0008323)2.29357163
68Epileptiform EEG discharges (HP:0011182)2.27689543
69Dyschromatopsia (HP:0007641)2.26398729
70Increased circulating renin level (HP:0000848)2.24601663
71Truncal ataxia (HP:0002078)2.23880412
72Generalized tonic-clonic seizures (HP:0002069)2.22979621
73Scotoma (HP:0000575)2.21217828
74Abnormality of the periventricular white matter (HP:0002518)2.20375515
75Clumsiness (HP:0002312)2.20265418
76Rapidly progressive (HP:0003678)2.19979548
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.17997764
78Dialeptic seizures (HP:0011146)2.17979260
79Diminished motivation (HP:0000745)2.16448392
80Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15646116
81Neuroendocrine neoplasm (HP:0100634)2.14030541
82Absence seizures (HP:0002121)2.13067485
83Limb dystonia (HP:0002451)2.12855717
84Foot dorsiflexor weakness (HP:0009027)2.10474070
85Bundle branch block (HP:0011710)2.10213160
86Parakeratosis (HP:0001036)2.06219235
87Impaired vibration sensation in the lower limbs (HP:0002166)2.05855672
88Broad-based gait (HP:0002136)2.04850608
89Impaired smooth pursuit (HP:0007772)2.04631369
90Spastic tetraparesis (HP:0001285)2.03930157
91Gaze-evoked nystagmus (HP:0000640)2.03910349
92Metabolic alkalosis (HP:0200114)2.03211526
93Abnormality of saccadic eye movements (HP:0000570)2.02817859
94Hammertoe (HP:0001765)2.02566932
95Stereotypic behavior (HP:0000733)2.02527405
96Morphological abnormality of the inner ear (HP:0011390)2.01551410
97Impaired social interactions (HP:0000735)2.00157061
98Abnormal social behavior (HP:0012433)2.00157061
99EEG with generalized epileptiform discharges (HP:0011198)1.98931243
100Thickened helices (HP:0000391)1.98120578
101Focal dystonia (HP:0004373)1.98091818
102Bronchomalacia (HP:0002780)1.97520790
103Impaired vibratory sensation (HP:0002495)1.97078255
104Abnormality of the lower motor neuron (HP:0002366)1.96978012
105Craniofacial dystonia (HP:0012179)1.96712121
106CNS hypomyelination (HP:0003429)1.96464732
107Morphological abnormality of the pyramidal tract (HP:0002062)1.95898582
108Abnormal eating behavior (HP:0100738)1.95521870
109Split foot (HP:0001839)1.94532928
110Vaginal atresia (HP:0000148)1.94056810
111Abnormality of ocular smooth pursuit (HP:0000617)1.93819884
112Febrile seizures (HP:0002373)1.93735435
113Decreased motor nerve conduction velocity (HP:0003431)1.93461601
114Ventricular fibrillation (HP:0001663)1.93124426
115Hemiparesis (HP:0001269)1.92183494
116Axonal loss (HP:0003447)1.91504353
117Gait imbalance (HP:0002141)1.90754013
118Neuronal loss in central nervous system (HP:0002529)1.89988731
119Abnormality of the foot musculature (HP:0001436)1.89977946
120Lower limb asymmetry (HP:0100559)1.89490804
121Bowel incontinence (HP:0002607)1.89182234
122Rigidity (HP:0002063)1.87905358
123Genital tract atresia (HP:0001827)1.87647725
124Leukodystrophy (HP:0002415)1.87554999
125Choroideremia (HP:0001139)1.85482379
126Hypsarrhythmia (HP:0002521)1.84915107
127Abnormality of cochlea (HP:0000375)1.84434709
128Mutism (HP:0002300)1.84366456
129Choreoathetosis (HP:0001266)1.84295230
130Dementia (HP:0000726)1.81744499
131Generalized myoclonic seizures (HP:0002123)1.80699670
132Distal sensory impairment (HP:0002936)1.79834256
133Diplopia (HP:0000651)1.79827285
134Abnormality of binocular vision (HP:0011514)1.79827285
135Hypokalemic alkalosis (HP:0001949)1.77750302
136Amblyopia (HP:0000646)1.77232255
137Memory impairment (HP:0002354)1.77080667
138Heart block (HP:0012722)1.72379746

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.22012495
2OXSR13.10773666
3EPHA42.88511872
4WNK12.23179344
5UHMK12.20087053
6EPHB12.12547259
7PAK62.12120278
8MAP3K92.05603892
9CDK192.01357392
10RIPK12.01250502
11MAPKAPK52.00338758
12PRKD31.97449490
13NTRK31.96666905
14PRPF4B1.90218341
15NTRK11.89894048
16PINK11.88820405
17PKN11.87970353
18WNK41.80761157
19SGK2231.79729169
20SGK4941.79729169
21PNCK1.73461186
22MARK11.72885266
23FGFR21.70884585
24PHKG21.67323731
25PHKG11.67323731
26KSR21.64571533
27TYRO31.59733420
28CAMK2B1.55831994
29TNIK1.54664274
30NTRK21.51720346
31BCR1.49862184
32MINK11.46199549
33LIMK11.45152430
34RIPK41.42800399
35ARAF1.35499601
36NEK61.34042402
37CDK51.33475846
38MAP3K41.32841637
39CAMK2D1.32700586
40ROCK21.29062194
41PBK1.28672087
42SGK21.24694172
43TNK21.22363158
44CAMK2G1.19726802
45CSNK1A1L1.18254613
46DAPK21.12323746
47CSNK1G31.10694019
48LATS21.09602065
49CSNK1G21.08654422
50ICK1.07150153
51SGK31.06287198
52MET1.05455077
53DAPK11.03025938
54PRKCH1.02800427
55MAP3K21.00751414
56CAMKK10.99434876
57MAPK150.99005360
58SIK20.98204135
59PAK30.97523728
60CAMK2A0.97048428
61MAPK120.95370977
62LMTK20.91498849
63CDK140.90726821
64MAP3K130.90448064
65MAP2K70.89899607
66FES0.88176062
67MARK20.87704954
68CDK150.86019666
69BRSK10.85644084
70FGR0.83025299
71IRAK20.82534134
72CSNK1G10.82435346
73STK110.81795284
74CDK180.80978258
75PRKD10.80834418
76CASK0.79767780
77CAMK1G0.79007907
78MAPK130.77543543
79GRK50.75576173
80CDK11A0.75270302
81PDPK10.74990726
82GRK10.73257225
83PRKCG0.72345842
84MUSK0.69107055
85MAP2K40.68801797
86STK380.65972646
87PRKCE0.62341302
88FYN0.59846011
89CAMK40.59742093
90PRKCQ0.57738649
91PLK20.56070729
92TESK20.54582237
93MAP3K110.53426453
94PDK10.53080925
95DYRK1A0.52559697
96MAPK100.52490510
97RET0.51249167
98DDR20.51206666
99CAMKK20.51179803
100CAMK10.51079908
101TESK10.51079381
102SGK10.49466181
103DAPK30.49042152
104ERBB20.46073990
105ALK0.44228300
106PRKCZ0.44073212
107RPS6KA30.42022017
108CSNK1A10.41908453
109HIPK20.41508480
110MAP3K10.41499801
111BRAF0.41266244
112KSR10.40924995
113PRKG10.40058264
114BMPR20.39911781
115PRKG20.37605129
116PRKACB0.37412001
117ROCK10.37111776
118RAF10.36622504
119BMX0.34216779
120PRKCA0.33071529
121SRC0.30761448
122MAPK40.28681622
123JAK20.26460305
124RPS6KB10.25839126
125MAPK80.25402771
126GSK3B0.25274596
127MAP2K10.24930909

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.50453193
2Phototransduction_Homo sapiens_hsa047443.30283070
3Olfactory transduction_Homo sapiens_hsa047402.85783332
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.64893717
5GABAergic synapse_Homo sapiens_hsa047272.54546354
6Synaptic vesicle cycle_Homo sapiens_hsa047212.38831403
7Glutamatergic synapse_Homo sapiens_hsa047242.22794988
8Fatty acid elongation_Homo sapiens_hsa000622.08828690
9Nicotine addiction_Homo sapiens_hsa050332.07883096
10Morphine addiction_Homo sapiens_hsa050322.06084867
11Circadian entrainment_Homo sapiens_hsa047131.98361725
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.97963142
13Steroid biosynthesis_Homo sapiens_hsa001001.91007863
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78867663
15Ether lipid metabolism_Homo sapiens_hsa005651.66127051
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.63887019
17Gastric acid secretion_Homo sapiens_hsa049711.61087639
18Dopaminergic synapse_Homo sapiens_hsa047281.60623377
19Salivary secretion_Homo sapiens_hsa049701.58612189
20Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.56493986
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.56440246
22Cholinergic synapse_Homo sapiens_hsa047251.51112019
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.46892490
24Cocaine addiction_Homo sapiens_hsa050301.43184721
25Serotonergic synapse_Homo sapiens_hsa047261.42754146
26Amphetamine addiction_Homo sapiens_hsa050311.42147746
27Long-term potentiation_Homo sapiens_hsa047201.37364898
28Insulin secretion_Homo sapiens_hsa049111.35852003
29Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.31283026
30Long-term depression_Homo sapiens_hsa047301.29386984
31Axon guidance_Homo sapiens_hsa043601.25195146
32Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.19420370
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.17363017
34Vitamin B6 metabolism_Homo sapiens_hsa007501.16581068
35Taste transduction_Homo sapiens_hsa047421.15136282
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13132400
37Renin secretion_Homo sapiens_hsa049241.10826337
38Butanoate metabolism_Homo sapiens_hsa006501.08537149
39Collecting duct acid secretion_Homo sapiens_hsa049661.06015024
40Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05957899
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03031329
42cAMP signaling pathway_Homo sapiens_hsa040241.01647637
43SNARE interactions in vesicular transport_Homo sapiens_hsa041300.96976904
44Gap junction_Homo sapiens_hsa045400.95842192
45Oxytocin signaling pathway_Homo sapiens_hsa049210.95413517
46beta-Alanine metabolism_Homo sapiens_hsa004100.95376280
47Carbohydrate digestion and absorption_Homo sapiens_hsa049730.95266226
48Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.92152867
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89617083
50Calcium signaling pathway_Homo sapiens_hsa040200.89385967
51Pancreatic secretion_Homo sapiens_hsa049720.87036042
52Vibrio cholerae infection_Homo sapiens_hsa051100.85820913
53Phospholipase D signaling pathway_Homo sapiens_hsa040720.85441210
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.85335277
55Cardiac muscle contraction_Homo sapiens_hsa042600.84217005
56Sulfur metabolism_Homo sapiens_hsa009200.83530246
57GnRH signaling pathway_Homo sapiens_hsa049120.82732608
58Fatty acid biosynthesis_Homo sapiens_hsa000610.82667349
59Sphingolipid metabolism_Homo sapiens_hsa006000.82147972
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82117374
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.82006038
62Renal cell carcinoma_Homo sapiens_hsa052110.78910758
63Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77042200
64Dorso-ventral axis formation_Homo sapiens_hsa043200.76954494
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75013640
66Sphingolipid signaling pathway_Homo sapiens_hsa040710.74228369
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.72561158
68Rap1 signaling pathway_Homo sapiens_hsa040150.72297184
69Bile secretion_Homo sapiens_hsa049760.71525368
70Oocyte meiosis_Homo sapiens_hsa041140.70030471
71Glycerophospholipid metabolism_Homo sapiens_hsa005640.69878009
72VEGF signaling pathway_Homo sapiens_hsa043700.69850090
73Endocytosis_Homo sapiens_hsa041440.69369769
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69254976
75ErbB signaling pathway_Homo sapiens_hsa040120.67519843
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66808581
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.66010167
78Tight junction_Homo sapiens_hsa045300.65979085
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65094091
80Histidine metabolism_Homo sapiens_hsa003400.64154009
81Ras signaling pathway_Homo sapiens_hsa040140.63778246
82Melanogenesis_Homo sapiens_hsa049160.61804208
83Ovarian steroidogenesis_Homo sapiens_hsa049130.61081579
84Thyroid hormone synthesis_Homo sapiens_hsa049180.60532251
85Circadian rhythm_Homo sapiens_hsa047100.57609411
86Estrogen signaling pathway_Homo sapiens_hsa049150.55051206
87Mineral absorption_Homo sapiens_hsa049780.54991447
88Glucagon signaling pathway_Homo sapiens_hsa049220.51214308
89Choline metabolism in cancer_Homo sapiens_hsa052310.50102724
90Alzheimers disease_Homo sapiens_hsa050100.49597898
91Oxidative phosphorylation_Homo sapiens_hsa001900.49540861
92Prion diseases_Homo sapiens_hsa050200.48795960
93Arginine and proline metabolism_Homo sapiens_hsa003300.48463639
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47871639
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47751184
96Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.47080061
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47063039
98Linoleic acid metabolism_Homo sapiens_hsa005910.46737730
99Dilated cardiomyopathy_Homo sapiens_hsa054140.44706256
100Fatty acid metabolism_Homo sapiens_hsa012120.43955592
101Type II diabetes mellitus_Homo sapiens_hsa049300.43841563
102Inositol phosphate metabolism_Homo sapiens_hsa005620.43088765
103Alcoholism_Homo sapiens_hsa050340.42306528
104MAPK signaling pathway_Homo sapiens_hsa040100.42234036
105Arginine biosynthesis_Homo sapiens_hsa002200.40107365
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.40106729
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39846549
108Parkinsons disease_Homo sapiens_hsa050120.39714490
109Lysosome_Homo sapiens_hsa041420.38976739
110Glioma_Homo sapiens_hsa052140.37669155
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.36971963
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36315853
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36074394
114Propanoate metabolism_Homo sapiens_hsa006400.35983032
115mTOR signaling pathway_Homo sapiens_hsa041500.35581714
116Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.34518839
117Wnt signaling pathway_Homo sapiens_hsa043100.32480751
118Endometrial cancer_Homo sapiens_hsa052130.32084497
119Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31353066
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.30349410
121ABC transporters_Homo sapiens_hsa020100.28574538
122Insulin signaling pathway_Homo sapiens_hsa049100.27879148
123Phenylalanine metabolism_Homo sapiens_hsa003600.27176190
124AMPK signaling pathway_Homo sapiens_hsa041520.26671483

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