Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.02815358 |
2 | modulation by symbiont of host immune response (GO:0052553) | 6.02815358 |
3 | positive regulation by symbiont of host defense response (GO:0052509) | 6.02815358 |
4 | modulation by symbiont of host defense response (GO:0052031) | 6.02815358 |
5 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.02815358 |
6 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.02815358 |
7 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.86356475 |
8 | macrophage activation involved in immune response (GO:0002281) | 5.17181536 |
9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.85423714 |
10 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.83256189 |
11 | negative regulation of interleukin-12 production (GO:0032695) | 4.81903289 |
12 | negative regulation of cell killing (GO:0031342) | 4.75362153 |
13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.75362153 |
14 | microglial cell activation (GO:0001774) | 4.43330729 |
15 | positive regulation of interferon-alpha production (GO:0032727) | 4.04969848 |
16 | detection of other organism (GO:0098543) | 4.04539173 |
17 | B cell receptor signaling pathway (GO:0050853) | 3.93811993 |
18 | immunoglobulin mediated immune response (GO:0016064) | 3.90900566 |
19 | detection of bacterium (GO:0016045) | 3.90178757 |
20 | neutrophil activation involved in immune response (GO:0002283) | 3.89610975 |
21 | positive regulation of antigen processing and presentation (GO:0002579) | 3.84014865 |
22 | positive regulation of B cell differentiation (GO:0045579) | 3.84004393 |
23 | regulation of interferon-alpha production (GO:0032647) | 3.80877824 |
24 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.69911950 |
25 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.65233430 |
26 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.63115890 |
27 | response to host immune response (GO:0052572) | 3.63115890 |
28 | macrophage activation (GO:0042116) | 3.62051346 |
29 | negative regulation of granulocyte differentiation (GO:0030853) | 3.60563575 |
30 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.54957021 |
31 | type I interferon signaling pathway (GO:0060337) | 3.54508816 |
32 | cellular response to type I interferon (GO:0071357) | 3.54508816 |
33 | response to type I interferon (GO:0034340) | 3.51583662 |
34 | detection of external biotic stimulus (GO:0098581) | 3.51258967 |
35 | detection of molecule of bacterial origin (GO:0032490) | 3.46762392 |
36 | defense response to protozoan (GO:0042832) | 3.42797727 |
37 | pinocytosis (GO:0006907) | 3.39617711 |
38 | NIK/NF-kappaB signaling (GO:0038061) | 3.39586512 |
39 | response to host (GO:0075136) | 3.38754954 |
40 | response to host defenses (GO:0052200) | 3.38754954 |
41 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.38754954 |
42 | germinal center formation (GO:0002467) | 3.36909260 |
43 | cellular response to zinc ion (GO:0071294) | 3.35296749 |
44 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.34958824 |
45 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.34291067 |
46 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.33321618 |
47 | respiratory burst (GO:0045730) | 3.31695059 |
48 | T-helper 1 type immune response (GO:0042088) | 3.28126654 |
49 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.26922288 |
50 | response to protozoan (GO:0001562) | 3.24383216 |
51 | positive regulation of type 2 immune response (GO:0002830) | 3.24079343 |
52 | myeloid cell activation involved in immune response (GO:0002275) | 3.21985116 |
53 | regulation of T cell tolerance induction (GO:0002664) | 3.20535563 |
54 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.18378203 |
55 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.16902022 |
56 | leukocyte aggregation (GO:0070486) | 3.16817869 |
57 | regulation of antigen processing and presentation (GO:0002577) | 3.16323056 |
58 | T cell migration (GO:0072678) | 3.15521951 |
59 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.14294237 |
60 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.13923968 |
61 | I-kappaB phosphorylation (GO:0007252) | 3.12358958 |
62 | regulation of leukocyte degranulation (GO:0043300) | 3.11406103 |
63 | detection of biotic stimulus (GO:0009595) | 3.11061297 |
64 | response to muramyl dipeptide (GO:0032495) | 3.08613787 |
65 | negative regulation of T cell mediated immunity (GO:0002710) | 3.06669356 |
66 | neutrophil activation (GO:0042119) | 3.05049158 |
67 | granulocyte activation (GO:0036230) | 3.03225927 |
68 | substrate-dependent cell migration (GO:0006929) | 3.02241477 |
69 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.01982361 |
70 | regulation of B cell differentiation (GO:0045577) | 3.01867936 |
71 | cortical actin cytoskeleton organization (GO:0030866) | 2.98788448 |
72 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.95458484 |
73 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.95353671 |
74 | regulation of tolerance induction (GO:0002643) | 2.93985196 |
75 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.92776615 |
76 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.92776615 |
77 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.90432222 |
78 | regulation of type 2 immune response (GO:0002828) | 2.88705619 |
79 | regulation of mast cell degranulation (GO:0043304) | 2.87754635 |
80 | mature B cell differentiation (GO:0002335) | 2.86642785 |
81 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.86124375 |
82 | positive thymic T cell selection (GO:0045059) | 2.85828977 |
83 | monocyte chemotaxis (GO:0002548) | 2.84665646 |
84 | cellular extravasation (GO:0045123) | 2.84376112 |
85 | cellular response to interferon-gamma (GO:0071346) | 2.84052028 |
86 | negative regulation of phagocytosis (GO:0050765) | 2.83290647 |
87 | cytidine deamination (GO:0009972) | 2.81506972 |
88 | cytidine metabolic process (GO:0046087) | 2.81506972 |
89 | cytidine catabolic process (GO:0006216) | 2.81506972 |
90 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.80180302 |
91 | hyaluronan catabolic process (GO:0030214) | 2.78210872 |
92 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.78045274 |
93 | germ cell migration (GO:0008354) | 2.75386375 |
94 | positive regulation of mast cell activation (GO:0033005) | 2.75369320 |
95 | response to laminar fluid shear stress (GO:0034616) | 2.75301884 |
96 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.75245974 |
97 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.75055877 |
98 | response to peptidoglycan (GO:0032494) | 2.74484491 |
99 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.73895005 |
100 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.71698766 |
101 | regulation of interleukin-12 production (GO:0032655) | 2.70920966 |
102 | negative regulation of interleukin-6 production (GO:0032715) | 2.70777733 |
103 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.68538366 |
104 | positive regulation of mast cell degranulation (GO:0043306) | 2.68538366 |
105 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.65890825 |
106 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.64726343 |
107 | negative regulation of innate immune response (GO:0045824) | 2.64152664 |
108 | response to interferon-gamma (GO:0034341) | 2.63589426 |
109 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.63387280 |
110 | cortical cytoskeleton organization (GO:0030865) | 2.62835131 |
111 | B cell mediated immunity (GO:0019724) | 2.62543845 |
112 | regulation of macrophage cytokine production (GO:0010935) | 2.62097634 |
113 | myeloid dendritic cell differentiation (GO:0043011) | 2.62012465 |
114 | tolerance induction (GO:0002507) | 2.60644815 |
115 | myeloid leukocyte activation (GO:0002274) | 2.60195441 |
116 | negative regulation of B cell proliferation (GO:0030889) | 2.59909433 |
117 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.59198080 |
118 | cardiac myofibril assembly (GO:0055003) | 2.56284858 |
119 | semaphorin-plexin signaling pathway (GO:0071526) | 2.56120103 |
120 | positive regulation of B cell mediated immunity (GO:0002714) | 2.55888623 |
121 | natural killer cell differentiation (GO:0001779) | 2.54367432 |
122 | mannose metabolic process (GO:0006013) | 2.54099028 |
123 | positive regulation of interferon-beta production (GO:0032728) | 2.53675272 |
124 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.52289707 |
125 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.50459020 |
126 | positive regulation of macrophage cytokine production (GO:0060907) | 2.50245818 |
127 | regulation of monocyte differentiation (GO:0045655) | 2.50055910 |
128 | myeloid dendritic cell activation (GO:0001773) | 2.50046942 |
129 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.48545201 |
130 | response to fluid shear stress (GO:0034405) | 2.48250387 |
131 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.47985919 |
132 | regulation of mast cell activation (GO:0033003) | 2.46439012 |
133 | apoptotic cell clearance (GO:0043277) | 2.45957409 |
134 | B cell homeostasis (GO:0001782) | 2.45065274 |
135 | barbed-end actin filament capping (GO:0051016) | 2.44514701 |
136 | regulation of gamma-delta T cell activation (GO:0046643) | 2.43331541 |
137 | dendritic cell differentiation (GO:0097028) | 2.43047307 |
138 | positive regulation of lamellipodium assembly (GO:0010592) | 2.40715797 |
139 | glomerular visceral epithelial cell development (GO:0072015) | 2.39445704 |
140 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 2.38615716 |
141 | ruffle organization (GO:0031529) | 2.35265361 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.94794718 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.36704880 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.10876781 |
4 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.89606393 |
5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.65231374 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.34877788 |
7 | * VDR_21846776_ChIP-Seq_THP-1_Human | 3.33228673 |
8 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.08329844 |
9 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.00557892 |
10 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.95156766 |
11 | MYC_22102868_ChIP-Seq_BL_Human | 2.84713611 |
12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.81112882 |
13 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.75494902 |
14 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.65628093 |
15 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.57107823 |
16 | SPI1_23127762_ChIP-Seq_K562_Human | 2.52629082 |
17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.51755363 |
18 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.49799106 |
19 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.48313502 |
20 | * KDM2B_26808549_Chip-Seq_DND41_Human | 2.42406065 |
21 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.38030632 |
22 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.32024264 |
23 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.27098889 |
24 | MAF_26560356_Chip-Seq_TH1_Human | 2.26039451 |
25 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.24723354 |
26 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.23388441 |
27 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.21673642 |
28 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.17718131 |
29 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.17035712 |
30 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.01737549 |
31 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.90418086 |
32 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.89394537 |
33 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.89044297 |
34 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.88632198 |
35 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.87103000 |
36 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.81701226 |
37 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.77179349 |
38 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.76628628 |
39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76168834 |
40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.74577472 |
41 | * PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.73842787 |
42 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.69045484 |
43 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.67317183 |
44 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.66919249 |
45 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.65935252 |
46 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.63266477 |
47 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.62671049 |
48 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.62340931 |
49 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.61041357 |
50 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.61011557 |
51 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.58068414 |
52 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.56928352 |
53 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55529233 |
54 | * MYB_26560356_Chip-Seq_TH2_Human | 1.50672027 |
55 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.50128471 |
56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.49161807 |
57 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.40550237 |
58 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.38515550 |
59 | * MAF_26560356_Chip-Seq_TH2_Human | 1.36251603 |
60 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.34690443 |
61 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32513350 |
62 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31448132 |
63 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.31303656 |
64 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.31148966 |
65 | * MYB_26560356_Chip-Seq_TH1_Human | 1.30242700 |
66 | * CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.29825451 |
67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.25489125 |
68 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.24683516 |
69 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.24401839 |
70 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.20349556 |
71 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.20256420 |
72 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.20256420 |
73 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.18640496 |
74 | * PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15893913 |
75 | * SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15719945 |
76 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14567562 |
77 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.12404958 |
78 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12262540 |
79 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.11973111 |
80 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.11301917 |
81 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.10108233 |
82 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.09766713 |
83 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09758228 |
84 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09644914 |
85 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07448049 |
86 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.06652983 |
87 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06199830 |
88 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.05782075 |
89 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.05340013 |
90 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05116341 |
91 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.04890734 |
92 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.04058664 |
93 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.03607898 |
94 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.02930405 |
95 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.02866347 |
96 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.02816990 |
97 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02532347 |
98 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.02120392 |
99 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.02057690 |
100 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.96267375 |
101 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.95992209 |
102 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.95643876 |
103 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.95388251 |
104 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.95245624 |
105 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93773458 |
106 | GATA1_22025678_ChIP-Seq_K562_Human | 0.93767131 |
107 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.92463024 |
108 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.92442086 |
109 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90142558 |
110 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.90079040 |
111 | GATA1_19941826_ChIP-Seq_K562_Human | 0.89912910 |
112 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.88843348 |
113 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.88198605 |
114 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.88153251 |
115 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.87971662 |
116 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.87302344 |
117 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.84335871 |
118 | GATA3_26560356_Chip-Seq_TH2_Human | 0.84327925 |
119 | GATA2_19941826_ChIP-Seq_K562_Human | 0.84079034 |
120 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.84070952 |
121 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82505180 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003303_peritoneal_inflammation | 5.14080017 |
2 | MP0001835_abnormal_antigen_presentation | 3.67904496 |
3 | MP0004510_myositis | 3.62371809 |
4 | MP0005058_abnormal_lysosome_morphology | 3.28884512 |
5 | MP0006082_CNS_inflammation | 2.55955311 |
6 | MP0003436_decreased_susceptibility_to | 2.43244836 |
7 | MP0002452_abnormal_antigen_presenting | 2.39818422 |
8 | MP0005387_immune_system_phenotype | 2.34873434 |
9 | MP0001790_abnormal_immune_system | 2.34873434 |
10 | MP0003172_abnormal_lysosome_physiology | 2.32824073 |
11 | MP0001800_abnormal_humoral_immune | 2.32341266 |
12 | MP0002419_abnormal_innate_immunity | 2.26821370 |
13 | MP0005000_abnormal_immune_tolerance | 2.19670740 |
14 | MP0003300_gastrointestinal_ulcer | 2.19111483 |
15 | MP0000685_abnormal_immune_system | 2.18406468 |
16 | MP0005257_abnormal_intraocular_pressure | 2.07114891 |
17 | MP0000569_abnormal_digit_pigmentation | 1.96183751 |
18 | MP0009278_abnormal_bone_marrow | 1.94201282 |
19 | MP0009764_decreased_sensitivity_to | 1.93874951 |
20 | MP0002723_abnormal_immune_serum | 1.93776212 |
21 | MP0005671_abnormal_response_to | 1.92820180 |
22 | MP0001819_abnormal_immune_cell | 1.89405904 |
23 | MP0002420_abnormal_adaptive_immunity | 1.88125345 |
24 | MP0003191_abnormal_cellular_cholesterol | 1.87394684 |
25 | MP0003828_pulmonary_edema | 1.82498990 |
26 | MP0004084_abnormal_cardiac_muscle | 1.79239310 |
27 | MP0005025_abnormal_response_to | 1.78058520 |
28 | MP0002148_abnormal_hypersensitivity_rea | 1.76866078 |
29 | MP0008438_abnormal_cutaneous_collagen | 1.76779112 |
30 | MP0001879_abnormal_lymphatic_vessel | 1.73268877 |
31 | MP0000343_altered_response_to | 1.70307755 |
32 | MP0005464_abnormal_platelet_physiology | 1.69203528 |
33 | MP0008004_abnormal_stomach_pH | 1.68325436 |
34 | MP0005451_abnormal_body_composition | 1.67205868 |
35 | MP0000767_abnormal_smooth_muscle | 1.62782362 |
36 | MP0003279_aneurysm | 1.62383123 |
37 | MP0003566_abnormal_cell_adhesion | 1.55330486 |
38 | MP0003763_abnormal_thymus_physiology | 1.53945673 |
39 | MP0003705_abnormal_hypodermis_morpholog | 1.53665485 |
40 | MP0001533_abnormal_skeleton_physiology | 1.48203199 |
41 | MP0000465_gastrointestinal_hemorrhage | 1.47634059 |
42 | MP0000716_abnormal_immune_system | 1.47046744 |
43 | MP0002405_respiratory_system_inflammati | 1.46725961 |
44 | MP0002398_abnormal_bone_marrow | 1.45039785 |
45 | MP0010368_abnormal_lymphatic_system | 1.42425023 |
46 | MP0000751_myopathy | 1.39008754 |
47 | MP0009785_altered_susceptibility_to | 1.36606151 |
48 | MP0001958_emphysema | 1.36229062 |
49 | MP0004808_abnormal_hematopoietic_stem | 1.35990285 |
50 | MP0008260_abnormal_autophagy | 1.34865344 |
51 | MP0000733_abnormal_muscle_development | 1.32325697 |
52 | MP0000689_abnormal_spleen_morphology | 1.31887303 |
53 | MP0003091_abnormal_cell_migration | 1.31403963 |
54 | MP0003448_altered_tumor_morphology | 1.30212352 |
55 | MP0002429_abnormal_blood_cell | 1.21144524 |
56 | MP0005174_abnormal_tail_pigmentation | 1.18934878 |
57 | MP0005076_abnormal_cell_differentiation | 1.17396976 |
58 | MP0010630_abnormal_cardiac_muscle | 1.17373447 |
59 | MP0009840_abnormal_foam_cell | 1.17058619 |
60 | MP0002396_abnormal_hematopoietic_system | 1.16302552 |
61 | MP0002722_abnormal_immune_system | 1.15512835 |
62 | * MP0002998_abnormal_bone_remodeling | 1.14187870 |
63 | MP0000750_abnormal_muscle_regeneration | 1.13038864 |
64 | MP0004087_abnormal_muscle_fiber | 1.12743306 |
65 | MP0002138_abnormal_hepatobiliary_system | 1.12598314 |
66 | MP0001845_abnormal_inflammatory_respons | 1.11574246 |
67 | MP0005167_abnormal_blood-brain_barrier | 1.11555146 |
68 | MP0002166_altered_tumor_susceptibility | 1.09414976 |
69 | MP0009333_abnormal_splenocyte_physiolog | 1.09246432 |
70 | MP0001853_heart_inflammation | 1.08996532 |
71 | MP0002933_joint_inflammation | 1.07685969 |
72 | MP0004883_abnormal_blood_vessel | 1.07296975 |
73 | MP0001663_abnormal_digestive_system | 1.06346498 |
74 | MP0004185_abnormal_adipocyte_glucose | 1.05398633 |
75 | MP0004130_abnormal_muscle_cell | 1.03206608 |
76 | MP0003806_abnormal_nucleotide_metabolis | 1.02061176 |
77 | MP0003690_abnormal_glial_cell | 1.01831375 |
78 | MP0000249_abnormal_blood_vessel | 1.01829733 |
79 | MP0003866_abnormal_defecation | 1.00583111 |
80 | MP0002837_dystrophic_cardiac_calcinosis | 1.00414101 |
81 | MP0001544_abnormal_cardiovascular_syste | 1.00176415 |
82 | MP0005385_cardiovascular_system_phenoty | 1.00176415 |
83 | MP0000604_amyloidosis | 0.99374063 |
84 | MP0003075_altered_response_to | 0.98000999 |
85 | MP0002972_abnormal_cardiac_muscle | 0.96936617 |
86 | MP0004036_abnormal_muscle_relaxation | 0.96045596 |
87 | MP0000749_muscle_degeneration | 0.95176448 |
88 | MP0005310_abnormal_salivary_gland | 0.90644806 |
89 | MP0003453_abnormal_keratinocyte_physiol | 0.89830841 |
90 | MP0005330_cardiomyopathy | 0.89341146 |
91 | MP0005166_decreased_susceptibility_to | 0.89254056 |
92 | MP0001851_eye_inflammation | 0.88165370 |
93 | MP0003045_fibrosis | 0.88076110 |
94 | MP0008469_abnormal_protein_level | 0.88031116 |
95 | MP0005164_abnormal_response_to | 0.87694450 |
96 | MP0010307_abnormal_tumor_latency | 0.85802432 |
97 | MP0000858_altered_metastatic_potential | 0.85726990 |
98 | MP0002332_abnormal_exercise_endurance | 0.85710663 |
99 | MP0009763_increased_sensitivity_to | 0.85334229 |
100 | MP0000703_abnormal_thymus_morphology | 0.85092632 |
101 | MP0003724_increased_susceptibility_to | 0.84997326 |
102 | MP0004484_altered_response_of | 0.84899387 |
103 | MP0008874_decreased_physiological_sensi | 0.83227995 |
104 | MP0001915_intracranial_hemorrhage | 0.82654418 |
105 | MP0003329_amyloid_beta_deposits | 0.81007009 |
106 | MP0002106_abnormal_muscle_physiology | 0.80802796 |
107 | MP0002128_abnormal_blood_circulation | 0.80531303 |
108 | MP0005197_abnormal_uvea_morphology | 0.79877181 |
109 | MP0003183_abnormal_peptide_metabolism | 0.79808525 |
110 | MP0002254_reproductive_system_inflammat | 0.79658029 |
111 | MP0008775_abnormal_heart_ventricle | 0.78287816 |
112 | MP0005397_hematopoietic_system_phenotyp | 0.78098406 |
113 | MP0001545_abnormal_hematopoietic_system | 0.78098406 |
114 | MP0002132_abnormal_respiratory_system | 0.76574966 |
115 | MP0002139_abnormal_hepatobiliary_system | 0.74849554 |
116 | MP0004947_skin_inflammation | 0.74075428 |
117 | MP0010155_abnormal_intestine_physiology | 0.73663150 |
118 | MP0005390_skeleton_phenotype | 0.73377288 |
119 | MP0006054_spinal_hemorrhage | 0.73215020 |
120 | MP0003646_muscle_fatigue | 0.72879293 |
121 | MP0000920_abnormal_myelination | 0.72848214 |
122 | MP0001873_stomach_inflammation | 0.72626807 |
123 | MP0000490_abnormal_crypts_of | 0.72338577 |
124 | MP0009765_abnormal_xenobiotic_induced | 0.71339142 |
125 | * MP0003795_abnormal_bone_structure | 0.70837076 |
126 | MP0002277_abnormal_respiratory_mucosa | 0.69034396 |
127 | MP0005381_digestive/alimentary_phenotyp | 0.65473565 |
128 | MP0003656_abnormal_erythrocyte_physiolo | 0.60893054 |
129 | MP0001542_abnormal_bone_strength | 0.59473204 |
130 | MP0001849_ear_inflammation | 0.52023991 |
131 | MP0005165_increased_susceptibility_to | 0.45384622 |
132 | MP0005595_abnormal_vascular_smooth | 0.44827557 |
133 | MP0005535_abnormal_body_temperature | 0.43461503 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 4.94047978 |
2 | Increased cerebral lipofuscin (HP:0011813) | 4.67144752 |
3 | Systemic lupus erythematosus (HP:0002725) | 4.57187244 |
4 | Orchitis (HP:0100796) | 4.27123644 |
5 | Eczematoid dermatitis (HP:0000976) | 4.26220646 |
6 | Recurrent bacterial skin infections (HP:0005406) | 4.21366047 |
7 | Optic neuritis (HP:0100653) | 4.08701888 |
8 | Retrobulbar optic neuritis (HP:0100654) | 4.08701888 |
9 | Stomatitis (HP:0010280) | 3.97759306 |
10 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.75847075 |
11 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.74665328 |
12 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.74665328 |
13 | Abnormality of glycolipid metabolism (HP:0010969) | 3.74665328 |
14 | Hematochezia (HP:0002573) | 3.65512138 |
15 | Cellulitis (HP:0100658) | 3.58971846 |
16 | Glomerulonephritis (HP:0000099) | 3.58726944 |
17 | Disinhibition (HP:0000734) | 3.57447951 |
18 | Cerebral aneurysm (HP:0004944) | 3.53011317 |
19 | Colitis (HP:0002583) | 3.52563729 |
20 | Purpura (HP:0000979) | 3.44004365 |
21 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 3.41225973 |
22 | Petechiae (HP:0000967) | 3.31214960 |
23 | Dysostosis multiplex (HP:0000943) | 3.30047223 |
24 | Prolonged bleeding time (HP:0003010) | 3.27336251 |
25 | Asymmetric septal hypertrophy (HP:0001670) | 3.22961304 |
26 | Spontaneous hematomas (HP:0007420) | 3.15670303 |
27 | Obstructive lung disease (HP:0006536) | 3.06167116 |
28 | Chronic obstructive pulmonary disease (HP:0006510) | 3.06167116 |
29 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.99948132 |
30 | Abnormality of macrophages (HP:0004311) | 2.99240295 |
31 | Encephalitis (HP:0002383) | 2.98240275 |
32 | Vacuolated lymphocytes (HP:0001922) | 2.98194068 |
33 | Gastrointestinal infarctions (HP:0005244) | 2.96299732 |
34 | Inflammation of the large intestine (HP:0002037) | 2.94206656 |
35 | Agammaglobulinemia (HP:0004432) | 2.93064430 |
36 | Pulmonary infiltrates (HP:0002113) | 2.87158702 |
37 | Axonal loss (HP:0003447) | 2.85319504 |
38 | Gastrointestinal inflammation (HP:0004386) | 2.85296758 |
39 | Epistaxis (HP:0000421) | 2.81921297 |
40 | Keratoconjunctivitis sicca (HP:0001097) | 2.80650957 |
41 | Increased IgE level (HP:0003212) | 2.80534206 |
42 | Increased IgM level (HP:0003496) | 2.79782306 |
43 | Hemoptysis (HP:0002105) | 2.79530158 |
44 | Urticaria (HP:0001025) | 2.74270311 |
45 | Recurrent skin infections (HP:0001581) | 2.69889794 |
46 | Recurrent fungal infections (HP:0002841) | 2.66496036 |
47 | Mucopolysacchariduria (HP:0008155) | 2.65429516 |
48 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.65429516 |
49 | Sudden death (HP:0001699) | 2.63817323 |
50 | Mediastinal lymphadenopathy (HP:0100721) | 2.63232915 |
51 | Recurrent viral infections (HP:0004429) | 2.59655715 |
52 | T lymphocytopenia (HP:0005403) | 2.54429678 |
53 | Keratoconjunctivitis (HP:0001096) | 2.52776971 |
54 | Leukocytosis (HP:0001974) | 2.52496594 |
55 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.52345709 |
56 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.51344957 |
57 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.51344957 |
58 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.51344957 |
59 | Papilloma (HP:0012740) | 2.49923199 |
60 | Verrucae (HP:0200043) | 2.49923199 |
61 | Aortic aneurysm (HP:0004942) | 2.48754316 |
62 | Gastrointestinal stroma tumor (HP:0100723) | 2.45909677 |
63 | Osteomyelitis (HP:0002754) | 2.43690237 |
64 | Amyloidosis (HP:0011034) | 2.43612318 |
65 | Diminished motivation (HP:0000745) | 2.39895784 |
66 | Gingival bleeding (HP:0000225) | 2.39484853 |
67 | Meningitis (HP:0001287) | 2.39334276 |
68 | Nephritis (HP:0000123) | 2.37879246 |
69 | Abnormality of T cell number (HP:0011839) | 2.36862619 |
70 | Loss of speech (HP:0002371) | 2.35979604 |
71 | Increased serum ferritin (HP:0003281) | 2.35360849 |
72 | Hyperacusis (HP:0010780) | 2.35107490 |
73 | Apathy (HP:0000741) | 2.33522290 |
74 | Myositis (HP:0100614) | 2.31140817 |
75 | Basal ganglia calcification (HP:0002135) | 2.27901596 |
76 | Increased density of long bones (HP:0006392) | 2.27697960 |
77 | Disproportionate tall stature (HP:0001519) | 2.26920476 |
78 | Arterial tortuosity (HP:0005116) | 2.23319513 |
79 | Hepatosplenomegaly (HP:0001433) | 2.23046763 |
80 | Bicuspid aortic valve (HP:0001647) | 2.22371387 |
81 | Pulmonary embolism (HP:0002204) | 2.22095693 |
82 | Hypergammaglobulinemia (HP:0010702) | 2.21841542 |
83 | Myocardial infarction (HP:0001658) | 2.21377025 |
84 | Lymphopenia (HP:0001888) | 2.18740428 |
85 | Inappropriate behavior (HP:0000719) | 2.18453539 |
86 | Restrictive lung disease (HP:0002091) | 2.17725846 |
87 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.15531876 |
88 | Recurrent cutaneous fungal infections (HP:0011370) | 2.15531876 |
89 | Emphysema (HP:0002097) | 2.14672615 |
90 | Agnosia (HP:0010524) | 2.13882876 |
91 | Aortic dissection (HP:0002647) | 2.13724215 |
92 | J-shaped sella turcica (HP:0002680) | 2.12284536 |
93 | Interstitial pulmonary disease (HP:0006530) | 2.11881609 |
94 | Episodic fever (HP:0001954) | 2.10132937 |
95 | Pustule (HP:0200039) | 2.09515093 |
96 | Abnormality of the nasal mucosa (HP:0000433) | 2.09453157 |
97 | Gingivitis (HP:0000230) | 2.09058312 |
98 | Neurofibrillary tangles (HP:0002185) | 2.09016833 |
99 | Conjunctival telangiectasia (HP:0000524) | 2.08392142 |
100 | Striae distensae (HP:0001065) | 2.07845886 |
101 | Abnormal platelet volume (HP:0011876) | 2.07737260 |
102 | Autoimmune thrombocytopenia (HP:0001973) | 2.06957925 |
103 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.05624482 |
104 | Mucosal telangiectasiae (HP:0100579) | 2.03690742 |
105 | Granulocytopenia (HP:0001913) | 2.03642842 |
106 | Ventricular tachycardia (HP:0004756) | 2.01411458 |
107 | Panhypogammaglobulinemia (HP:0003139) | 2.01393449 |
108 | Chronic otitis media (HP:0000389) | 2.01319353 |
109 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.00934257 |
110 | Peritonitis (HP:0002586) | 1.99729005 |
111 | Mitral valve prolapse (HP:0001634) | 1.99149503 |
112 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.99001941 |
113 | Mutism (HP:0002300) | 1.98725108 |
114 | Abnormality of iron homeostasis (HP:0011031) | 1.98460187 |
115 | Thoracic kyphosis (HP:0002942) | 1.95852312 |
116 | Abnormality of the pleura (HP:0002103) | 1.95566180 |
117 | Vascular tortuosity (HP:0004948) | 1.95050568 |
118 | Chest pain (HP:0100749) | 1.94787985 |
119 | Polyneuropathy (HP:0001271) | 1.92734649 |
120 | Gangrene (HP:0100758) | 1.92626037 |
121 | Abnormality of T cells (HP:0002843) | 1.92382713 |
122 | Malnutrition (HP:0004395) | 1.90597871 |
123 | Neuronal loss in central nervous system (HP:0002529) | 1.90451685 |
124 | Viral hepatitis (HP:0006562) | 1.90240321 |
125 | Recurrent lower respiratory tract infections (HP:0002783) | 1.89408451 |
126 | Vasculitis (HP:0002633) | 1.87481946 |
127 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.85363245 |
128 | Spondylolisthesis (HP:0003302) | 1.85148787 |
129 | Arterial thrombosis (HP:0004420) | 1.84890027 |
130 | Recurrent pneumonia (HP:0006532) | 1.82594998 |
131 | Frequent falls (HP:0002359) | 1.82466468 |
132 | Retinal atrophy (HP:0001105) | 1.82187526 |
133 | Polycythemia (HP:0001901) | 1.81447888 |
134 | Recurrent bronchitis (HP:0002837) | 1.81132788 |
135 | Persistence of primary teeth (HP:0006335) | 1.79632413 |
136 | Scapular winging (HP:0003691) | 1.77590230 |
137 | Abnormality of complement system (HP:0005339) | 1.74634793 |
138 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.70325231 |
139 | Osteolytic defects of the hand bones (HP:0009699) | 1.70325231 |
140 | Acrocyanosis (HP:0001063) | 1.69766594 |
141 | Sepsis (HP:0100806) | 1.69416719 |
142 | Rapidly progressive (HP:0003678) | 1.69308259 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TGFBR2 | 3.90728572 |
2 | TRIB3 | 3.65456507 |
3 | MAP3K10 | 3.62579387 |
4 | BLK | 3.34919123 |
5 | MAP4K1 | 3.09567414 |
6 | PKN2 | 3.01116925 |
7 | PRPF4B | 2.74716925 |
8 | TTN | 2.63838348 |
9 | CSF1R | 2.58123468 |
10 | RIPK4 | 2.55308402 |
11 | KIT | 2.49065959 |
12 | TBK1 | 2.37478459 |
13 | SIK2 | 2.33631237 |
14 | ERN1 | 2.27097191 |
15 | TYK2 | 2.19202986 |
16 | MAP3K11 | 2.05592407 |
17 | TLK1 | 1.93055495 |
18 | TAOK2 | 1.88715686 |
19 | TAOK1 | 1.87448724 |
20 | FES | 1.74730476 |
21 | DMPK | 1.61878185 |
22 | LRRK2 | 1.54669656 |
23 | PAK4 | 1.52272237 |
24 | TNK2 | 1.49587081 |
25 | CAMK1G | 1.48033040 |
26 | MAP3K3 | 1.44678290 |
27 | HCK | 1.42890619 |
28 | PTK6 | 1.42870583 |
29 | SYK | 1.40641233 |
30 | ICK | 1.39583651 |
31 | ZAP70 | 1.38749340 |
32 | EEF2K | 1.35260543 |
33 | CLK1 | 1.34139572 |
34 | DDR2 | 1.34035268 |
35 | CDC42BPA | 1.32424285 |
36 | MAP2K3 | 1.30296847 |
37 | EPHB1 | 1.28249173 |
38 | CAMK1D | 1.26713389 |
39 | IRAK4 | 1.25747641 |
40 | CSK | 1.25634207 |
41 | JAK1 | 1.23290903 |
42 | TXK | 1.21764191 |
43 | MAP3K1 | 1.21613082 |
44 | SIK3 | 1.17700999 |
45 | KDR | 1.16863141 |
46 | GRK7 | 1.16016262 |
47 | ILK | 1.13724806 |
48 | BTK | 1.13101451 |
49 | STK10 | 1.11492097 |
50 | FGR | 1.02410765 |
51 | IKBKB | 1.00031250 |
52 | MAP3K14 | 0.98224741 |
53 | LYN | 0.95007873 |
54 | LCK | 0.93760984 |
55 | JAK3 | 0.93082155 |
56 | TIE1 | 0.92898433 |
57 | MARK2 | 0.92840617 |
58 | IRAK2 | 0.92391207 |
59 | NEK9 | 0.91906406 |
60 | RPS6KA4 | 0.89632712 |
61 | RIPK1 | 0.88784068 |
62 | BMPR2 | 0.87741172 |
63 | DAPK3 | 0.87734107 |
64 | DYRK1B | 0.85797627 |
65 | MAPK12 | 0.82608355 |
66 | TEC | 0.82051910 |
67 | SCYL2 | 0.81325579 |
68 | GRK6 | 0.80895713 |
69 | EPHB2 | 0.80692270 |
70 | IKBKE | 0.80480362 |
71 | TGFBR1 | 0.79085712 |
72 | MARK3 | 0.72873525 |
73 | NME2 | 0.72823421 |
74 | PRKD1 | 0.72729834 |
75 | KSR2 | 0.71652524 |
76 | STK4 | 0.71301635 |
77 | MAP3K5 | 0.70420117 |
78 | MATK | 0.69925467 |
79 | PAK2 | 0.68588688 |
80 | MYLK | 0.68569544 |
81 | IRAK1 | 0.68252320 |
82 | EGFR | 0.67904612 |
83 | IRAK3 | 0.67193912 |
84 | CDK19 | 0.66882979 |
85 | TAOK3 | 0.65875126 |
86 | JAK2 | 0.65784558 |
87 | CHUK | 0.65435749 |
88 | PDGFRA | 0.64587106 |
89 | MAPK7 | 0.64230575 |
90 | PTK2B | 0.62949087 |
91 | ITK | 0.61161051 |
92 | ARAF | 0.61067284 |
93 | RPS6KL1 | 0.60820922 |
94 | SIK1 | 0.60424183 |
95 | BMX | 0.59681091 |
96 | TYRO3 | 0.59040918 |
97 | PKN1 | 0.58293729 |
98 | CAMK4 | 0.56702716 |
99 | PIM2 | 0.55232044 |
100 | TESK2 | 0.53521354 |
101 | PHKG2 | 0.53033589 |
102 | PHKG1 | 0.53033589 |
103 | FYN | 0.51561976 |
104 | HIPK2 | 0.51491042 |
105 | FGFR3 | 0.50997262 |
106 | PRKCQ | 0.48944961 |
107 | DAPK2 | 0.48779317 |
108 | CAMKK1 | 0.45869970 |
109 | CDK6 | 0.45852959 |
110 | CAMKK2 | 0.45450758 |
111 | DYRK3 | 0.43762741 |
112 | ABL1 | 0.43122524 |
113 | PDPK1 | 0.43119732 |
114 | PDK1 | 0.42663529 |
115 | PIK3CG | 0.42404283 |
116 | YES1 | 0.42061030 |
117 | PIM1 | 0.40887049 |
118 | MAPKAPK2 | 0.40243988 |
119 | MOS | 0.40157804 |
120 | RET | 0.39686282 |
121 | MAPK4 | 0.39032758 |
122 | PRKCH | 0.38221535 |
123 | EPHA3 | 0.35520473 |
124 | SRC | 0.35001220 |
125 | MAP3K13 | 0.34318072 |
126 | PDGFRB | 0.33222343 |
127 | ADRBK2 | 0.33192889 |
128 | RPS6KA2 | 0.33027588 |
129 | SGK3 | 0.32550904 |
130 | PRKD2 | 0.30584977 |
131 | PRKCD | 0.30352672 |
132 | PRKG2 | 0.30061462 |
133 | ALK | 0.29977405 |
134 | RPS6KA6 | 0.29536613 |
135 | FGFR4 | 0.29309960 |
136 | ABL2 | 0.28681017 |
137 | INSR | 0.27815642 |
138 | RPS6KC1 | 0.26747770 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Allograft rejection_Homo sapiens_hsa05330 | 2.86791140 |
2 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.83183895 |
3 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.75921473 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.62345165 |
5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.60000478 |
6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.50567666 |
7 | Asthma_Homo sapiens_hsa05310 | 2.45204028 |
8 | Leishmaniasis_Homo sapiens_hsa05140 | 2.41815919 |
9 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.24085785 |
10 | Lysosome_Homo sapiens_hsa04142 | 2.04405754 |
11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.97064255 |
12 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.91985396 |
13 | Other glycan degradation_Homo sapiens_hsa00511 | 1.90470947 |
14 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.85126503 |
15 | Tuberculosis_Homo sapiens_hsa05152 | 1.73532315 |
16 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.72746070 |
17 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.64513375 |
18 | Pertussis_Homo sapiens_hsa05133 | 1.61919403 |
19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.53942402 |
20 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.53732386 |
21 | Viral myocarditis_Homo sapiens_hsa05416 | 1.53407113 |
22 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.52639555 |
23 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.44160933 |
24 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.42723805 |
25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.41710838 |
26 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.41328015 |
27 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.41165093 |
28 | Salmonella infection_Homo sapiens_hsa05132 | 1.39732691 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.36952854 |
30 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.36781569 |
31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.34074888 |
32 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.34013685 |
33 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.32526394 |
34 | Shigellosis_Homo sapiens_hsa05131 | 1.32264470 |
35 | Measles_Homo sapiens_hsa05162 | 1.26511977 |
36 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.24662934 |
37 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.24195383 |
38 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.24041339 |
39 | Phagosome_Homo sapiens_hsa04145 | 1.23822794 |
40 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.23639868 |
41 | Apoptosis_Homo sapiens_hsa04210 | 1.23000084 |
42 | Platelet activation_Homo sapiens_hsa04611 | 1.21016501 |
43 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.18074382 |
44 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.18035771 |
45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.16411040 |
46 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.14051950 |
47 | Malaria_Homo sapiens_hsa05144 | 1.13486187 |
48 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.03841644 |
49 | Influenza A_Homo sapiens_hsa05164 | 1.02730285 |
50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.02092878 |
51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.01526293 |
52 | Focal adhesion_Homo sapiens_hsa04510 | 1.00705664 |
53 | Glioma_Homo sapiens_hsa05214 | 1.00670237 |
54 | Hepatitis B_Homo sapiens_hsa05161 | 0.99266776 |
55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.98486564 |
56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.97796926 |
57 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.96916250 |
58 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.95485320 |
59 | Endocytosis_Homo sapiens_hsa04144 | 0.93821287 |
60 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.93744508 |
61 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.93582439 |
62 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.90062454 |
63 | Legionellosis_Homo sapiens_hsa05134 | 0.88582551 |
64 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.87881613 |
65 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.86512578 |
66 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.86236236 |
67 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.85755750 |
68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.85100742 |
69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.84363009 |
70 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.82603072 |
71 | Amoebiasis_Homo sapiens_hsa05146 | 0.82445570 |
72 | Colorectal cancer_Homo sapiens_hsa05210 | 0.81929629 |
73 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.81899928 |
74 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.81289970 |
75 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.79031902 |
76 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.76904959 |
77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.76793803 |
78 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.74956087 |
79 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.74792218 |
80 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.73632056 |
81 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.72833342 |
82 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.69712375 |
83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.69684122 |
84 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.69310149 |
85 | HTLV-I infection_Homo sapiens_hsa05166 | 0.69279580 |
86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.67501728 |
87 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.67123337 |
88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.65199294 |
89 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.64123263 |
90 | Bladder cancer_Homo sapiens_hsa05219 | 0.63373253 |
91 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.62403444 |
92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.62057993 |
93 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61481396 |
94 | Adherens junction_Homo sapiens_hsa04520 | 0.59708479 |
95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59599194 |
96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.58879697 |
97 | Hepatitis C_Homo sapiens_hsa05160 | 0.58720941 |
98 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.58096753 |
99 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.56007812 |
100 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.55534152 |
101 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54789113 |
102 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.53783359 |
103 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.52357057 |
104 | Insulin resistance_Homo sapiens_hsa04931 | 0.52157638 |
105 | Prion diseases_Homo sapiens_hsa05020 | 0.51058824 |
106 | Pathways in cancer_Homo sapiens_hsa05200 | 0.50671763 |
107 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.50469970 |
108 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50371193 |
109 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49585257 |
110 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.48046210 |
111 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.47968155 |
112 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.47860122 |
113 | Axon guidance_Homo sapiens_hsa04360 | 0.47619765 |
114 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37049853 |
115 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.33354458 |
116 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.29651870 |
117 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.26586365 |
118 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.26536556 |