Rank | Gene Set | Z-score |
---|---|---|
1 | exogenous drug catabolic process (GO:0042738) | 9.81366114 |
2 | epoxygenase P450 pathway (GO:0019373) | 8.52540376 |
3 | omega-hydroxylase P450 pathway (GO:0097267) | 8.52360650 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.56380455 |
5 | L-phenylalanine catabolic process (GO:0006559) | 7.56380455 |
6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.23463230 |
7 | L-phenylalanine metabolic process (GO:0006558) | 7.23463230 |
8 | aromatic amino acid family catabolic process (GO:0009074) | 6.80915616 |
9 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.47270914 |
10 | drug metabolic process (GO:0017144) | 6.21377972 |
11 | tryptophan catabolic process (GO:0006569) | 6.15458835 |
12 | indole-containing compound catabolic process (GO:0042436) | 6.15458835 |
13 | indolalkylamine catabolic process (GO:0046218) | 6.15458835 |
14 | oxidative demethylation (GO:0070989) | 6.08338685 |
15 | kynurenine metabolic process (GO:0070189) | 6.04468506 |
16 | bile acid biosynthetic process (GO:0006699) | 5.96001032 |
17 | glyoxylate metabolic process (GO:0046487) | 5.79167438 |
18 | tryptophan metabolic process (GO:0006568) | 5.78948555 |
19 | high-density lipoprotein particle remodeling (GO:0034375) | 5.72682928 |
20 | urea metabolic process (GO:0019627) | 5.69336936 |
21 | urea cycle (GO:0000050) | 5.69336936 |
22 | alpha-linolenic acid metabolic process (GO:0036109) | 5.63727017 |
23 | protein carboxylation (GO:0018214) | 5.47227848 |
24 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.47227848 |
25 | regulation of protein activation cascade (GO:2000257) | 5.42162191 |
26 | complement activation, alternative pathway (GO:0006957) | 5.39958284 |
27 | regulation of plasminogen activation (GO:0010755) | 5.34219076 |
28 | cysteine metabolic process (GO:0006534) | 5.33709862 |
29 | sulfur amino acid catabolic process (GO:0000098) | 5.33366682 |
30 | * negative regulation of fibrinolysis (GO:0051918) | 5.28953822 |
31 | nitrogen cycle metabolic process (GO:0071941) | 5.23090842 |
32 | ethanol metabolic process (GO:0006067) | 5.20718601 |
33 | * regulation of fibrinolysis (GO:0051917) | 5.20688978 |
34 | phenylpropanoid metabolic process (GO:0009698) | 5.18455928 |
35 | serine family amino acid catabolic process (GO:0009071) | 5.13596347 |
36 | bile acid metabolic process (GO:0008206) | 5.10889621 |
37 | regulation of complement activation (GO:0030449) | 5.04503804 |
38 | regulation of cholesterol esterification (GO:0010872) | 5.04406361 |
39 | reverse cholesterol transport (GO:0043691) | 5.00466253 |
40 | aromatic amino acid family metabolic process (GO:0009072) | 4.94605613 |
41 | protein-lipid complex remodeling (GO:0034368) | 4.91093419 |
42 | macromolecular complex remodeling (GO:0034367) | 4.91093419 |
43 | plasma lipoprotein particle remodeling (GO:0034369) | 4.91093419 |
44 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.88379227 |
45 | regulation of triglyceride catabolic process (GO:0010896) | 4.86996714 |
46 | S-adenosylmethionine metabolic process (GO:0046500) | 4.80636547 |
47 | tyrosine metabolic process (GO:0006570) | 4.80156140 |
48 | homocysteine metabolic process (GO:0050667) | 4.73166426 |
49 | phospholipid efflux (GO:0033700) | 4.71559503 |
50 | regulation of humoral immune response (GO:0002920) | 4.69788759 |
51 | acylglycerol homeostasis (GO:0055090) | 4.66399528 |
52 | triglyceride homeostasis (GO:0070328) | 4.66399528 |
53 | negative regulation of sterol transport (GO:0032372) | 4.65841156 |
54 | negative regulation of cholesterol transport (GO:0032375) | 4.65841156 |
55 | alpha-amino acid catabolic process (GO:1901606) | 4.63656873 |
56 | * negative regulation of hemostasis (GO:1900047) | 4.61319612 |
57 | * negative regulation of blood coagulation (GO:0030195) | 4.61319612 |
58 | amino-acid betaine metabolic process (GO:0006577) | 4.60622644 |
59 | lysine catabolic process (GO:0006554) | 4.55675653 |
60 | lysine metabolic process (GO:0006553) | 4.55675653 |
61 | negative regulation of protein activation cascade (GO:2000258) | 4.54385813 |
62 | plasma lipoprotein particle clearance (GO:0034381) | 4.51570141 |
63 | cellular ketone body metabolic process (GO:0046950) | 4.48719808 |
64 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.46991364 |
65 | glycine metabolic process (GO:0006544) | 4.43469160 |
66 | bile acid and bile salt transport (GO:0015721) | 4.41464735 |
67 | alkaloid metabolic process (GO:0009820) | 4.39846163 |
68 | imidazole-containing compound metabolic process (GO:0052803) | 4.37026667 |
69 | indolalkylamine metabolic process (GO:0006586) | 4.35694331 |
70 | cholesterol efflux (GO:0033344) | 4.34782654 |
71 | coenzyme catabolic process (GO:0009109) | 4.33310405 |
72 | amine catabolic process (GO:0009310) | 4.26856998 |
73 | cellular biogenic amine catabolic process (GO:0042402) | 4.26856998 |
74 | cellular amino acid catabolic process (GO:0009063) | 4.26038310 |
75 | glutamate metabolic process (GO:0006536) | 4.24322637 |
76 | cellular glucuronidation (GO:0052695) | 4.22816906 |
77 | * negative regulation of coagulation (GO:0050819) | 4.18112119 |
78 | serine family amino acid metabolic process (GO:0009069) | 4.17457978 |
79 | * negative regulation of wound healing (GO:0061045) | 4.14641698 |
80 | benzene-containing compound metabolic process (GO:0042537) | 4.14364034 |
81 | plasma lipoprotein particle assembly (GO:0034377) | 4.13686776 |
82 | low-density lipoprotein particle remodeling (GO:0034374) | 4.13201181 |
83 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 4.13132641 |
84 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 4.13132641 |
85 | ethanol oxidation (GO:0006069) | 4.07539278 |
86 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.04773398 |
87 | cellular modified amino acid catabolic process (GO:0042219) | 4.03533878 |
88 | serine family amino acid biosynthetic process (GO:0009070) | 4.02870445 |
89 | arginine metabolic process (GO:0006525) | 4.02775766 |
90 | aldehyde catabolic process (GO:0046185) | 3.99469666 |
91 | flavonoid metabolic process (GO:0009812) | 3.98541697 |
92 | blood coagulation, intrinsic pathway (GO:0007597) | 3.95692258 |
93 | intestinal cholesterol absorption (GO:0030299) | 3.94621690 |
94 | drug catabolic process (GO:0042737) | 3.90256325 |
95 | ketone body metabolic process (GO:1902224) | 3.88461489 |
96 | hormone catabolic process (GO:0042447) | 3.85344509 |
97 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.85317701 |
98 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.85317701 |
99 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.85156299 |
100 | negative regulation of lipase activity (GO:0060192) | 3.80948055 |
101 | positive regulation of lipid catabolic process (GO:0050996) | 3.80589977 |
102 | complement activation, classical pathway (GO:0006958) | 3.80551480 |
103 | cofactor catabolic process (GO:0051187) | 3.80214979 |
104 | phospholipid homeostasis (GO:0055091) | 3.79664987 |
105 | cholesterol homeostasis (GO:0042632) | 3.78316835 |
106 | protein activation cascade (GO:0072376) | 3.78272665 |
107 | complement activation (GO:0006956) | 3.77131524 |
108 | uronic acid metabolic process (GO:0006063) | 3.74750192 |
109 | glucuronate metabolic process (GO:0019585) | 3.74750192 |
110 | * fibrinolysis (GO:0042730) | 3.74280442 |
111 | polyketide metabolic process (GO:0030638) | 3.74249620 |
112 | doxorubicin metabolic process (GO:0044598) | 3.74249620 |
113 | daunorubicin metabolic process (GO:0044597) | 3.74249620 |
114 | plasma lipoprotein particle organization (GO:0071827) | 3.73511348 |
115 | carboxylic acid catabolic process (GO:0046395) | 3.72577122 |
116 | organic acid catabolic process (GO:0016054) | 3.72577122 |
117 | sterol homeostasis (GO:0055092) | 3.71973203 |
118 | * positive regulation of hemostasis (GO:1900048) | 3.71893073 |
119 | * positive regulation of blood coagulation (GO:0030194) | 3.71893073 |
120 | response to mercury ion (GO:0046689) | 3.71885842 |
121 | regulation of bile acid biosynthetic process (GO:0070857) | 3.70983644 |
122 | protein-lipid complex assembly (GO:0065005) | 3.70624875 |
123 | heme transport (GO:0015886) | 3.70170496 |
124 | short-chain fatty acid metabolic process (GO:0046459) | 3.65900779 |
125 | cytolysis (GO:0019835) | 3.64875055 |
126 | regulation of cholesterol homeostasis (GO:2000188) | 3.64381951 |
127 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.63940885 |
128 | acetyl-CoA metabolic process (GO:0006084) | 3.62705412 |
129 | opsonization (GO:0008228) | 3.58833437 |
130 | negative regulation of complement activation (GO:0045916) | 3.58253425 |
131 | acute-phase response (GO:0006953) | 3.58162877 |
132 | xenobiotic metabolic process (GO:0006805) | 3.53266274 |
133 | sodium-independent organic anion transport (GO:0043252) | 3.52242390 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.42148968 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.21922441 |
3 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.04718724 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.52661594 |
5 | * FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.19003729 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.18518217 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.87336400 |
8 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.07897757 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 4.06113738 |
10 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.08030969 |
11 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.9881196 |
12 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.99385385 |
13 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.95353406 |
14 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.61106227 |
15 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.54468505 |
16 | GATA1_22025678_ChIP-Seq_K562_Human | 1.46450438 |
17 | * HTT_18923047_ChIP-ChIP_STHdh_Human | 1.45808169 |
18 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.40798824 |
19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.30903446 |
20 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.20710968 |
21 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.19581974 |
22 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.17474842 |
23 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.14222063 |
24 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.03068809 |
25 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01170866 |
26 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.96068650 |
27 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.96014712 |
28 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.94181156 |
29 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.94015416 |
30 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.91120620 |
31 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.90540154 |
32 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.89312919 |
33 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.88748433 |
34 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.88363457 |
35 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.87102357 |
36 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.86607661 |
37 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.84128520 |
38 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.83986704 |
39 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.82736678 |
40 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.82380813 |
41 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.79969460 |
42 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.79270848 |
43 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.78712580 |
44 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.77892386 |
45 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.77821133 |
46 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77126529 |
47 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.76996642 |
48 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.76743818 |
49 | NFYA_21822215_ChIP-Seq_K562_Human | 0.75500321 |
50 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.74697991 |
51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.74673974 |
52 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.74442402 |
53 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.74318330 |
54 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.72890738 |
55 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.72886456 |
56 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.71865823 |
57 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.70899238 |
58 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.70755072 |
59 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.70135326 |
60 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.68065472 |
61 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.67844020 |
62 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.67077955 |
63 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.65333272 |
64 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.64754051 |
65 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.64586325 |
66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.64440355 |
67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.64389884 |
68 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.64181390 |
69 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.64181390 |
70 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.63759798 |
71 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.63686678 |
72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.62958178 |
73 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.62696922 |
74 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.61448807 |
75 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.61250625 |
76 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.60384298 |
77 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.59548142 |
78 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.59446871 |
79 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.59306400 |
80 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.58891605 |
81 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.58721410 |
82 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.57464580 |
83 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.57456328 |
84 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.56547667 |
85 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.56089834 |
86 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.55856075 |
87 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.54110189 |
88 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.54085856 |
89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.53613363 |
90 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.53112204 |
91 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.53076493 |
92 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.52939192 |
93 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.52924767 |
94 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.52591868 |
95 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.52335947 |
96 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.51976305 |
97 | NFYB_21822215_ChIP-Seq_K562_Human | 0.51940798 |
98 | AR_20517297_ChIP-Seq_VCAP_Human | 0.51435888 |
99 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.51319668 |
100 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.51295335 |
101 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.51225999 |
102 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.51204153 |
103 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.51174377 |
104 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.51028436 |
105 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.50695909 |
106 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.50607335 |
107 | CBP_21632823_ChIP-Seq_H3396_Human | 0.48033470 |
108 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.47117885 |
109 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.46374018 |
110 | * ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.45965439 |
111 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.45580050 |
112 | GATA1_19941826_ChIP-Seq_K562_Human | 0.45565962 |
113 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.45132009 |
114 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.44936605 |
115 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.44656955 |
116 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.43338537 |
117 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.42932394 |
118 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.41827663 |
119 | GATA2_19941826_ChIP-Seq_K562_Human | 0.41431074 |
120 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.40735938 |
121 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.40677283 |
122 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.40576674 |
123 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.39804835 |
124 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.39560007 |
125 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.39440093 |
126 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.39191598 |
127 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.39178588 |
128 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.38764812 |
129 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.38650875 |
130 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.38265885 |
131 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.37432436 |
132 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.35644819 |
133 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.35325379 |
134 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.34770632 |
135 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.34315282 |
136 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.33960906 |
137 | NCOR_22424771_ChIP-Seq_293T_Human | 0.33799869 |
138 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.33681892 |
139 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.32931052 |
140 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.32489463 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.36051398 |
2 | MP0005360_urolithiasis | 7.56051632 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.46404692 |
4 | MP0005365_abnormal_bile_salt | 6.21094794 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.10835052 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.27537509 |
7 | MP0003252_abnormal_bile_duct | 3.90548926 |
8 | MP0010329_abnormal_lipoprotein_level | 3.63607392 |
9 | MP0009840_abnormal_foam_cell | 3.35738862 |
10 | MP0005083_abnormal_biliary_tract | 3.15049792 |
11 | MP0003195_calcinosis | 2.85666740 |
12 | MP0005332_abnormal_amino_acid | 2.75112651 |
13 | MP0001666_abnormal_nutrient_absorption | 2.60124463 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.39072518 |
15 | * MP0000609_abnormal_liver_physiology | 2.15576368 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.12328265 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.11710910 |
18 | MP0002138_abnormal_hepatobiliary_system | 1.96885314 |
19 | MP0003868_abnormal_feces_composition | 1.91422372 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.83482445 |
21 | MP0001764_abnormal_homeostasis | 1.68122553 |
22 | MP0009697_abnormal_copulation | 1.65310022 |
23 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.57703978 |
24 | MP0005451_abnormal_body_composition | 1.42943891 |
25 | MP0003011_delayed_dark_adaptation | 1.42460706 |
26 | MP0003656_abnormal_erythrocyte_physiolo | 1.32104630 |
27 | MP0003186_abnormal_redox_activity | 1.26105463 |
28 | MP0009643_abnormal_urine_homeostasis | 1.22897598 |
29 | * MP0000598_abnormal_liver_morphology | 1.16633696 |
30 | MP0003705_abnormal_hypodermis_morpholog | 1.16309141 |
31 | MP0005647_abnormal_sex_gland | 1.15388412 |
32 | MP0000604_amyloidosis | 1.13048267 |
33 | MP0002254_reproductive_system_inflammat | 1.05322961 |
34 | MP0010368_abnormal_lymphatic_system | 1.01043316 |
35 | * MP0009763_increased_sensitivity_to | 0.99398906 |
36 | MP0005636_abnormal_mineral_homeostasis | 0.94419323 |
37 | * MP0008469_abnormal_protein_level | 0.87668207 |
38 | * MP0009642_abnormal_blood_homeostasis | 0.87558108 |
39 | * MP0009764_decreased_sensitivity_to | 0.86114137 |
40 | MP0005408_hypopigmentation | 0.85428886 |
41 | MP0001915_intracranial_hemorrhage | 0.84774860 |
42 | MP0006036_abnormal_mitochondrial_physio | 0.82338068 |
43 | MP0005187_abnormal_penis_morphology | 0.82240450 |
44 | MP0005376_homeostasis/metabolism_phenot | 0.81138725 |
45 | MP0009765_abnormal_xenobiotic_induced | 0.79436006 |
46 | MP0005084_abnormal_gallbladder_morpholo | 0.78773001 |
47 | MP0002078_abnormal_glucose_homeostasis | 0.78705271 |
48 | MP0005670_abnormal_white_adipose | 0.76377473 |
49 | MP0002876_abnormal_thyroid_physiology | 0.76215871 |
50 | MP0005220_abnormal_exocrine_pancreas | 0.73532047 |
51 | MP0002971_abnormal_brown_adipose | 0.72890241 |
52 | MP0003879_abnormal_hair_cell | 0.70871625 |
53 | MP0001661_extended_life_span | 0.70025334 |
54 | MP0005334_abnormal_fat_pad | 0.69864916 |
55 | MP0004130_abnormal_muscle_cell | 0.69143047 |
56 | MP0005535_abnormal_body_temperature | 0.66886105 |
57 | MP0003329_amyloid_beta_deposits | 0.66011433 |
58 | MP0005266_abnormal_metabolism | 0.64620818 |
59 | MP0000639_abnormal_adrenal_gland | 0.63294541 |
60 | MP0001756_abnormal_urination | 0.58705552 |
61 | MP0005464_abnormal_platelet_physiology | 0.58155032 |
62 | MP0006035_abnormal_mitochondrial_morpho | 0.57401894 |
63 | MP0005448_abnormal_energy_balance | 0.57038468 |
64 | MP0009785_altered_susceptibility_to | 0.50800831 |
65 | MP0002822_catalepsy | 0.50629221 |
66 | MP0005395_other_phenotype | 0.50209438 |
67 | MP0003718_maternal_effect | 0.47066644 |
68 | MP0003638_abnormal_response/metabolism_ | 0.46910624 |
69 | MP0002928_abnormal_bile_duct | 0.45802936 |
70 | MP0008873_increased_physiological_sensi | 0.45318420 |
71 | MP0002136_abnormal_kidney_physiology | 0.45148467 |
72 | MP0003436_decreased_susceptibility_to | 0.44485964 |
73 | MP0003724_increased_susceptibility_to | 0.43461361 |
74 | MP0004782_abnormal_surfactant_physiolog | 0.42659302 |
75 | MP0003075_altered_response_to | 0.42421437 |
76 | MP0003953_abnormal_hormone_level | 0.41473150 |
77 | MP0002837_dystrophic_cardiac_calcinosis | 0.41024757 |
78 | MP0005248_abnormal_Harderian_gland | 0.40609565 |
79 | MP0005166_decreased_susceptibility_to | 0.38989269 |
80 | MP0004381_abnormal_hair_follicle | 0.38147186 |
81 | MP0008872_abnormal_physiological_respon | 0.38040199 |
82 | MP0009672_abnormal_birth_weight | 0.37727351 |
83 | MP0005666_abnormal_adipose_tissue | 0.36378547 |
84 | * MP0008874_decreased_physiological_sensi | 0.35506712 |
85 | * MP0003690_abnormal_glial_cell | 0.35454742 |
86 | MP0000579_abnormal_nail_morphology | 0.35417474 |
87 | MP0004883_abnormal_blood_vessel | 0.35367988 |
88 | MP0005058_abnormal_lysosome_morphology | 0.34000001 |
89 | MP0000566_synostosis | 0.33980803 |
90 | MP0009115_abnormal_fat_cell | 0.33819481 |
91 | MP0001243_abnormal_dermal_layer | 0.33413714 |
92 | MP0006082_CNS_inflammation | 0.33359448 |
93 | MP0002796_impaired_skin_barrier | 0.32803305 |
94 | MP0001853_heart_inflammation | 0.32062430 |
95 | MP0002168_other_aberrant_phenotype | 0.31964859 |
96 | MP0002970_abnormal_white_adipose | 0.31261884 |
97 | MP0000230_abnormal_systemic_arterial | 0.31080819 |
98 | MP0009384_cardiac_valve_regurgitation | 0.30263366 |
99 | MP0005164_abnormal_response_to | 0.27878681 |
100 | * MP0000249_abnormal_blood_vessel | 0.27521753 |
101 | MP0002132_abnormal_respiratory_system | 0.27175975 |
102 | MP0003632_abnormal_nervous_system | 0.26682817 |
103 | * MP0001845_abnormal_inflammatory_respons | 0.26415509 |
104 | MP0003959_abnormal_lean_body | 0.24832568 |
105 | MP0002090_abnormal_vision | 0.24200382 |
106 | MP0002060_abnormal_skin_morphology | 0.23722161 |
107 | MP0001986_abnormal_taste_sensitivity | 0.23700002 |
108 | MP0005167_abnormal_blood-brain_barrier | 0.23060964 |
109 | MP0000427_abnormal_hair_cycle | 0.22680565 |
110 | MP0000920_abnormal_myelination | 0.21371824 |
111 | MP0001545_abnormal_hematopoietic_system | 0.19575673 |
112 | MP0005397_hematopoietic_system_phenotyp | 0.19575673 |
113 | MP0001944_abnormal_pancreas_morphology | 0.19483005 |
114 | MP0004142_abnormal_muscle_tone | 0.19161036 |
115 | MP0002332_abnormal_exercise_endurance | 0.18638285 |
116 | MP0002089_abnormal_postnatal_growth/wei | 0.17302601 |
117 | MP0003878_abnormal_ear_physiology | 0.17179262 |
118 | MP0005377_hearing/vestibular/ear_phenot | 0.17179262 |
119 | * MP0005023_abnormal_wound_healing | 0.16900525 |
120 | MP0004043_abnormal_pH_regulation | 0.16887582 |
121 | MP0004272_abnormal_basement_membrane | 0.15136799 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 7.55357379 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.37012806 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.32653677 |
4 | Prolonged partial thromboplastin time (HP:0003645) | 6.70782355 |
5 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.66753715 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.48207165 |
7 | Xanthomatosis (HP:0000991) | 6.29894771 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.58096846 |
9 | Complement deficiency (HP:0004431) | 5.42700137 |
10 | Joint hemorrhage (HP:0005261) | 4.92600581 |
11 | Hypolipoproteinemia (HP:0010981) | 4.86904677 |
12 | Hyperammonemia (HP:0001987) | 4.59515091 |
13 | Abnormality of the common coagulation pathway (HP:0010990) | 4.58478437 |
14 | Epidermoid cyst (HP:0200040) | 4.48732141 |
15 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.44577138 |
16 | Hyperglycinemia (HP:0002154) | 4.42454465 |
17 | Hypoalphalipoproteinemia (HP:0003233) | 4.25898618 |
18 | Abnormality of methionine metabolism (HP:0010901) | 4.25868946 |
19 | Ketosis (HP:0001946) | 4.23189113 |
20 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.21984154 |
21 | Fat malabsorption (HP:0002630) | 4.14374484 |
22 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.08761762 |
23 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.07982370 |
24 | Abnormality of complement system (HP:0005339) | 3.96151336 |
25 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.88923529 |
26 | Abnormality of glycine metabolism (HP:0010895) | 3.88923529 |
27 | Hypoglycemic coma (HP:0001325) | 3.88701217 |
28 | Hyperglycinuria (HP:0003108) | 3.88347140 |
29 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.83376052 |
30 | Abnormality of the intrinsic pathway (HP:0010989) | 3.82727940 |
31 | Conjugated hyperbilirubinemia (HP:0002908) | 3.74826821 |
32 | Hypercholesterolemia (HP:0003124) | 3.67045931 |
33 | Hyperbilirubinemia (HP:0002904) | 3.38337678 |
34 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.32894358 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.29626040 |
36 | Spontaneous abortion (HP:0005268) | 3.17093350 |
37 | * Nephritis (HP:0000123) | 3.15706229 |
38 | Steatorrhea (HP:0002570) | 3.10947215 |
39 | Delayed CNS myelination (HP:0002188) | 3.09103453 |
40 | Hypochromic microcytic anemia (HP:0004840) | 3.06202435 |
41 | Abnormality of serum amino acid levels (HP:0003112) | 3.04778179 |
42 | Abnormality of nucleobase metabolism (HP:0010932) | 3.03445355 |
43 | Hepatocellular carcinoma (HP:0001402) | 2.99212627 |
44 | Ketoacidosis (HP:0001993) | 2.98922445 |
45 | Myocardial infarction (HP:0001658) | 2.95791580 |
46 | Osteomalacia (HP:0002749) | 2.84752277 |
47 | Skin nodule (HP:0200036) | 2.76907090 |
48 | Metabolic acidosis (HP:0001942) | 2.74165676 |
49 | Systemic lupus erythematosus (HP:0002725) | 2.73891229 |
50 | Acanthocytosis (HP:0001927) | 2.66620183 |
51 | Abnormality of purine metabolism (HP:0004352) | 2.63480007 |
52 | Vascular calcification (HP:0004934) | 2.59526540 |
53 | Lethargy (HP:0001254) | 2.58118649 |
54 | Purpura (HP:0000979) | 2.55831559 |
55 | Glomerulonephritis (HP:0000099) | 2.54713962 |
56 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.54370235 |
57 | Dicarboxylic aciduria (HP:0003215) | 2.54370235 |
58 | Hypoglycemic seizures (HP:0002173) | 2.52290832 |
59 | Fair hair (HP:0002286) | 2.50878742 |
60 | Abnormal gallbladder morphology (HP:0012437) | 2.50378090 |
61 | Cholelithiasis (HP:0001081) | 2.44434175 |
62 | Pulmonary embolism (HP:0002204) | 2.44134816 |
63 | Spastic diplegia (HP:0001264) | 2.44129767 |
64 | Mitral stenosis (HP:0001718) | 2.43570561 |
65 | Cerebral edema (HP:0002181) | 2.40335556 |
66 | Amyloidosis (HP:0011034) | 2.38141678 |
67 | Cholecystitis (HP:0001082) | 2.37946900 |
68 | Abnormal gallbladder physiology (HP:0012438) | 2.37946900 |
69 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.36994922 |
70 | Gout (HP:0001997) | 2.36268237 |
71 | Irritability (HP:0000737) | 2.33895120 |
72 | Neonatal onset (HP:0003623) | 2.33245663 |
73 | Gingival bleeding (HP:0000225) | 2.31835063 |
74 | Cardiovascular calcification (HP:0011915) | 2.30116088 |
75 | Neonatal hypoglycemia (HP:0001998) | 2.27393640 |
76 | Malnutrition (HP:0004395) | 2.24474836 |
77 | Esophageal varix (HP:0002040) | 2.22395761 |
78 | Menorrhagia (HP:0000132) | 2.21439704 |
79 | Hyperphosphaturia (HP:0003109) | 2.20146784 |
80 | Reduced antithrombin III activity (HP:0001976) | 2.19459148 |
81 | Thrombophlebitis (HP:0004418) | 2.15058121 |
82 | Late onset (HP:0003584) | 2.13598072 |
83 | Pancreatitis (HP:0001733) | 2.12969888 |
84 | Poikilocytosis (HP:0004447) | 2.12384503 |
85 | Sensorimotor neuropathy (HP:0007141) | 2.11701907 |
86 | Brushfield spots (HP:0001088) | 2.10701350 |
87 | Enlarged kidneys (HP:0000105) | 2.08687703 |
88 | Vomiting (HP:0002013) | 2.04878894 |
89 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.04737109 |
90 | Abnormality of urine glucose concentration (HP:0011016) | 2.03913005 |
91 | Glycosuria (HP:0003076) | 2.03913005 |
92 | Hemorrhage of the eye (HP:0011885) | 2.02770061 |
93 | Abnormality of the gallbladder (HP:0005264) | 2.02452666 |
94 | Opisthotonus (HP:0002179) | 2.01874076 |
95 | Joint swelling (HP:0001386) | 2.01001827 |
96 | Generalized aminoaciduria (HP:0002909) | 1.99346250 |
97 | Elevated alkaline phosphatase (HP:0003155) | 1.97856347 |
98 | Abnormality of iron homeostasis (HP:0011031) | 1.96206192 |
99 | Arthropathy (HP:0003040) | 1.93105208 |
100 | Rickets (HP:0002748) | 1.93076400 |
101 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.92494454 |
102 | Increased serum ferritin (HP:0003281) | 1.89936064 |
103 | Abnormality of the Achilles tendon (HP:0005109) | 1.87057518 |
104 | Hypophosphatemic rickets (HP:0004912) | 1.85684395 |
105 | Abnormal cartilage morphology (HP:0002763) | 1.85290725 |
106 | Renal cortical cysts (HP:0000803) | 1.83252279 |
107 | Bifid scrotum (HP:0000048) | 1.82945844 |
108 | Epistaxis (HP:0000421) | 1.82844279 |
109 | Hydroxyprolinuria (HP:0003080) | 1.80373929 |
110 | Abnormality of proline metabolism (HP:0010907) | 1.80373929 |
111 | Elevated hepatic transaminases (HP:0002910) | 1.80277851 |
112 | Gangrene (HP:0100758) | 1.79856896 |
113 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.79529894 |
114 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.79199343 |
115 | Status epilepticus (HP:0002133) | 1.77887738 |
116 | Alkalosis (HP:0001948) | 1.77705154 |
117 | Increased mean platelet volume (HP:0011877) | 1.75881895 |
118 | Reticulocytosis (HP:0001923) | 1.75069490 |
119 | Abnormal urine phosphate concentration (HP:0012599) | 1.75001100 |
120 | Hyperglycemia (HP:0003074) | 1.74079395 |
121 | Generalized hypopigmentation of hair (HP:0011358) | 1.72404680 |
122 | Abnormality of vitamin metabolism (HP:0100508) | 1.71642113 |
123 | Cerebral palsy (HP:0100021) | 1.64983535 |
124 | Abnormal biliary tract physiology (HP:0012439) | 1.62080034 |
125 | Bile duct proliferation (HP:0001408) | 1.62080034 |
126 | Abnormal platelet volume (HP:0011876) | 1.58158621 |
127 | Abnormal platelet function (HP:0011869) | 1.57287994 |
128 | Impaired platelet aggregation (HP:0003540) | 1.57287994 |
129 | Abnormal delivery (HP:0001787) | 1.56778781 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.15509662 |
2 | FGFR4 | 4.69024813 |
3 | SIK1 | 4.63502889 |
4 | ERN1 | 4.39707537 |
5 | TAOK3 | 3.20680754 |
6 | INSRR | 2.98842442 |
7 | ERBB4 | 2.87310828 |
8 | MAP2K4 | 2.34487648 |
9 | PKN2 | 2.23997301 |
10 | WNK3 | 2.20826137 |
11 | MST1R | 2.11075258 |
12 | NTRK3 | 1.98266862 |
13 | FLT3 | 1.92793593 |
14 | PIK3CG | 1.91564716 |
15 | MAPK11 | 1.89910724 |
16 | TRIB3 | 1.79539420 |
17 | TYK2 | 1.73648738 |
18 | DAPK2 | 1.67435373 |
19 | LATS1 | 1.61462282 |
20 | PTK6 | 1.48370334 |
21 | ABL2 | 1.47268572 |
22 | PRPF4B | 1.43844865 |
23 | CAMKK2 | 1.40399667 |
24 | NEK9 | 1.39622371 |
25 | NLK | 1.36239626 |
26 | FGFR2 | 1.36131230 |
27 | KDR | 1.34920799 |
28 | FRK | 1.32331495 |
29 | PDK2 | 1.24344694 |
30 | JAK2 | 1.24249056 |
31 | FER | 1.23836250 |
32 | MAP3K2 | 1.23010864 |
33 | MAP3K7 | 1.17641512 |
34 | TNK2 | 1.14740868 |
35 | PRKAA2 | 1.11410776 |
36 | PINK1 | 1.08944240 |
37 | GRK6 | 1.07650875 |
38 | MAP2K3 | 1.06840979 |
39 | TBK1 | 1.04477974 |
40 | JAK1 | 1.03712714 |
41 | ERBB2 | 1.03424880 |
42 | MAP3K10 | 1.01073563 |
43 | MAPK4 | 0.98160584 |
44 | PRKG1 | 0.95413391 |
45 | MAP3K14 | 0.93866863 |
46 | PRKCZ | 0.91360962 |
47 | PRKACA | 0.90893590 |
48 | EPHB1 | 0.89011907 |
49 | BRSK2 | 0.86910044 |
50 | MET | 0.86045523 |
51 | MAP3K3 | 0.82265945 |
52 | MAPK12 | 0.82112421 |
53 | CDK6 | 0.81502199 |
54 | EPHA3 | 0.81185041 |
55 | MAP3K11 | 0.81120795 |
56 | STK38L | 0.80400644 |
57 | TIE1 | 0.78479424 |
58 | MAPK15 | 0.78369616 |
59 | PRKACG | 0.77312718 |
60 | AKT3 | 0.77233664 |
61 | MYLK | 0.76405222 |
62 | DYRK1B | 0.72696591 |
63 | CAMK1D | 0.72535947 |
64 | CAMK2G | 0.70329054 |
65 | CSK | 0.70135223 |
66 | ACVR1B | 0.68655735 |
67 | CSNK1D | 0.68428638 |
68 | MAP3K12 | 0.66989039 |
69 | GSK3A | 0.66410484 |
70 | MAP2K6 | 0.64990344 |
71 | PRKAA1 | 0.64857595 |
72 | PRKCB | 0.63114312 |
73 | RIPK1 | 0.61687336 |
74 | SGK3 | 0.61582792 |
75 | CSNK1E | 0.60304434 |
76 | TGFBR2 | 0.58456719 |
77 | RPS6KA3 | 0.57472585 |
78 | CSF1R | 0.57470700 |
79 | FGFR3 | 0.57429534 |
80 | MAPK7 | 0.57089710 |
81 | IRAK3 | 0.56916328 |
82 | OXSR1 | 0.55678912 |
83 | PTK2 | 0.55566828 |
84 | IKBKE | 0.53896867 |
85 | ZAP70 | 0.53614020 |
86 | PRKCQ | 0.50576789 |
87 | PDPK1 | 0.50398111 |
88 | SGK1 | 0.49989239 |
89 | EPHA4 | 0.49973190 |
90 | CSNK1G1 | 0.47585066 |
91 | TAOK2 | 0.46730419 |
92 | BLK | 0.46563260 |
93 | SGK2 | 0.44542888 |
94 | GRK1 | 0.43972754 |
95 | IGF1R | 0.43788199 |
96 | CSNK2A1 | 0.43526474 |
97 | MAP3K5 | 0.43443815 |
98 | CAMKK1 | 0.43409181 |
99 | RET | 0.42709500 |
100 | MAP2K1 | 0.42638152 |
101 | CDK4 | 0.42554032 |
102 | SRC | 0.42414826 |
103 | BCR | 0.42197863 |
104 | PRKCG | 0.41388243 |
105 | MAP3K13 | 0.40956806 |
106 | KSR2 | 0.40416202 |
107 | ICK | 0.39868570 |
108 | PKN1 | 0.38699171 |
109 | CSNK2A2 | 0.38630444 |
110 | MAPKAPK3 | 0.36603090 |
111 | MTOR | 0.36351705 |
112 | MAP3K6 | 0.35958618 |
113 | CSNK1A1 | 0.34733407 |
114 | PBK | 0.33938077 |
115 | EGFR | 0.33904224 |
116 | CAMK4 | 0.32901102 |
117 | PDK1 | 0.31421846 |
118 | SGK494 | 0.31106746 |
119 | SGK223 | 0.31106746 |
120 | MAP3K1 | 0.29560678 |
121 | CSNK1G2 | 0.27391066 |
122 | PRKCA | 0.25714816 |
123 | PIK3CA | 0.25519281 |
124 | LATS2 | 0.25168689 |
125 | CAMK1G | 0.24709738 |
126 | CSNK1G3 | 0.24299271 |
127 | IRAK1 | 0.23672735 |
128 | PAK3 | 0.21354872 |
129 | ABL1 | 0.20496788 |
130 | IRAK2 | 0.20078790 |
131 | BMX | 0.19108496 |
132 | PRKACB | 0.18423744 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.53591091 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.65505826 |
3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.38523659 |
4 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.35732371 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.08005745 |
6 | * Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.77252573 |
7 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.71226204 |
8 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.68110468 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.64473086 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.55729124 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.48361426 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.37886989 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.24232690 |
14 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.15625237 |
15 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.15412582 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.06573570 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.96536198 |
18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.93947004 |
19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.92283890 |
20 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.92053657 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.91089433 |
22 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.86644871 |
23 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.81105186 |
24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.76999252 |
25 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.74845284 |
26 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.71119345 |
27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.70224840 |
28 | Retinol metabolism_Homo sapiens_hsa00830 | 1.69720393 |
29 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.65408294 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.62617871 |
31 | * Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.62415950 |
32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.58054127 |
33 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.55897341 |
34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50366664 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.50336998 |
36 | Bile secretion_Homo sapiens_hsa04976 | 1.49537524 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.44430403 |
38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.35730429 |
39 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.33932914 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.33508313 |
41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.31376760 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.27593526 |
43 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.22046009 |
44 | ABC transporters_Homo sapiens_hsa02010 | 1.21936216 |
45 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.20672348 |
46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.20084967 |
47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.19001462 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.12474031 |
49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02126185 |
50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01517016 |
51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.00719231 |
52 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.99212712 |
53 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.98654899 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96251058 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.94533175 |
56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.86870637 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.86839101 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82749944 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.81222541 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.77363397 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70069296 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.66936714 |
63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65601340 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.57084858 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.53968829 |
66 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.46160518 |
67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45540778 |
68 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43552610 |
69 | Prion diseases_Homo sapiens_hsa05020 | 0.36041575 |
70 | Pertussis_Homo sapiens_hsa05133 | 0.34819506 |
71 | Galactose metabolism_Homo sapiens_hsa00052 | 0.25906230 |
72 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.25696855 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.23045422 |
74 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.22856483 |
75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.21985291 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.21730600 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.20268633 |
78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.15226847 |
79 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.09831858 |
80 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01731460 |
81 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2416264 |
82 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2416206 |
83 | Bladder cancer_Homo sapiens_hsa05219 | -0.2410724 |
84 | Amoebiasis_Homo sapiens_hsa05146 | -0.2404462 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2345157 |
86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2314000 |
87 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | -0.2261114 |
88 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.2211004 |
89 | Type II diabetes mellitus_Homo sapiens_hsa04930 | -0.2131705 |
90 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.2076504 |
91 | Circadian rhythm_Homo sapiens_hsa04710 | -0.1971460 |
92 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1934319 |
93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1908405 |
94 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1868136 |
95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1827486 |
96 | Hepatitis C_Homo sapiens_hsa05160 | -0.1764065 |
97 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1697560 |
98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1633223 |
99 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1549882 |
100 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1451445 |
101 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1307747 |
102 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1232046 |
103 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.0993413 |
104 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0835597 |
105 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0761651 |
106 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0715830 |
107 | Mineral absorption_Homo sapiens_hsa04978 | -0.0669678 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0464620 |
109 | Other glycan degradation_Homo sapiens_hsa00511 | -0.0351506 |
110 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0223595 |