PLIN4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003 [PubMed 12840023]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1low-density lipoprotein particle clearance (GO:0034383)9.13186100
2regulation of sequestering of triglyceride (GO:0010889)8.00015689
3triglyceride catabolic process (GO:0019433)7.36630781
4acylglycerol catabolic process (GO:0046464)6.61951553
5neutral lipid catabolic process (GO:0046461)6.61951553
6white fat cell differentiation (GO:0050872)6.59523701
7brown fat cell differentiation (GO:0050873)6.55141019
8fatty acid transmembrane transport (GO:1902001)6.32609880
9valine metabolic process (GO:0006573)6.25055690
10biotin metabolic process (GO:0006768)6.17796596
11positive regulation of fatty acid beta-oxidation (GO:0032000)5.98828765
12lipid particle organization (GO:0034389)5.89557818
13carnitine shuttle (GO:0006853)5.87101754
14positive regulation of fatty acid oxidation (GO:0046321)5.75188911
15response to dietary excess (GO:0002021)5.31094875
16regulation of cholesterol storage (GO:0010885)5.19024024
17transcytosis (GO:0045056)5.18310799
18triglyceride biosynthetic process (GO:0019432)5.13207835
19fatty acid beta-oxidation (GO:0006635)5.11111499
20negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)4.95840434
21acylglycerol biosynthetic process (GO:0046463)4.94091141
22neutral lipid biosynthetic process (GO:0046460)4.94091141
23negative regulation of macrophage derived foam cell differentiation (GO:0010745)4.92970095
24glycerolipid catabolic process (GO:0046503)4.89159508
25carnitine transmembrane transport (GO:1902603)4.70310327
26lipid storage (GO:0019915)4.67667808
27regulation of fatty acid oxidation (GO:0046320)4.58396676
28regulation of fatty acid beta-oxidation (GO:0031998)4.52627510
29positive regulation of cellular response to insulin stimulus (GO:1900078)4.52340786
30polyol transport (GO:0015791)4.49044440
31fatty acid homeostasis (GO:0055089)4.48058745
32regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)4.46951929
33fatty acid oxidation (GO:0019395)4.44357176
34ovulation from ovarian follicle (GO:0001542)4.36911181
35lipid oxidation (GO:0034440)4.35803298
36fatty acid catabolic process (GO:0009062)4.35017510
37amino-acid betaine transport (GO:0015838)4.31153678
38carnitine transport (GO:0015879)4.31153678
39branched-chain amino acid metabolic process (GO:0009081)4.25120594
40triglyceride metabolic process (GO:0006641)4.17155326
41acyl-CoA biosynthetic process (GO:0071616)4.13628516
42thioester biosynthetic process (GO:0035384)4.13628516
43coenzyme A biosynthetic process (GO:0015937)4.09402343
44fatty-acyl-CoA metabolic process (GO:0035337)4.05895986
45branched-chain amino acid catabolic process (GO:0009083)4.05091727
46fatty-acyl-CoA biosynthetic process (GO:0046949)4.04542458
47protein heterotrimerization (GO:0070208)4.03798914
48ethanol oxidation (GO:0006069)4.03273400
49oxaloacetate metabolic process (GO:0006107)4.00277583
50positive regulation of fatty acid metabolic process (GO:0045923)3.99920445
51positive regulation of insulin receptor signaling pathway (GO:0046628)3.99170432
52negative regulation of smooth muscle cell migration (GO:0014912)3.97671308
53acylglycerol metabolic process (GO:0006639)3.95519830
54acetyl-CoA metabolic process (GO:0006084)3.92717430
55positive regulation of lipid catabolic process (GO:0050996)3.92502310
56plasma lipoprotein particle clearance (GO:0034381)3.91692853
57neutral lipid metabolic process (GO:0006638)3.89856715
58long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.89130816
59positive regulation of glucose import (GO:0046326)3.82872388
60response to phenylpropanoid (GO:0080184)3.80108943
61negative regulation of protein autophosphorylation (GO:0031953)3.76058278
62long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.76037748
63alpha-linolenic acid metabolic process (GO:0036109)3.74348929
64regulation of gonadotropin secretion (GO:0032276)3.73990850
65positive regulation of lipid storage (GO:0010884)3.73287455
66tricarboxylic acid metabolic process (GO:0072350)3.72440418
67cellular response to epinephrine stimulus (GO:0071872)3.71291060
68regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.70940086
69negative regulation of amino acid transport (GO:0051956)3.70232688
70intracellular lipid transport (GO:0032365)3.70039890
71negative regulation of gluconeogenesis (GO:0045721)3.66386436
72glycerol metabolic process (GO:0006071)3.64038055
73negative regulation of metanephros development (GO:0072217)3.63271139
74regulation of cAMP-dependent protein kinase activity (GO:2000479)3.62776709
75NADH metabolic process (GO:0006734)3.60803494
76cGMP-mediated signaling (GO:0019934)3.60553394
77regulation of macrophage derived foam cell differentiation (GO:0010743)3.59469859
78negative regulation of granulocyte differentiation (GO:0030853)3.59233543
79regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640)3.56715738
802-oxoglutarate metabolic process (GO:0006103)3.56538447
81retina vasculature morphogenesis in camera-type eye (GO:0061299)3.53398107
82tricarboxylic acid cycle (GO:0006099)3.51772019
83CDP-diacylglycerol metabolic process (GO:0046341)3.51415689
84regulation of receptor binding (GO:1900120)3.49479227
85positive regulation of glycolytic process (GO:0045821)3.48364964
86negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.44808074
87growth hormone receptor signaling pathway (GO:0060396)3.40928376
88regulation of lipoprotein metabolic process (GO:0050746)3.39030146
89positive regulation of triglyceride lipase activity (GO:0061365)3.38992961
90positive regulation of lipoprotein lipase activity (GO:0051006)3.38992961
91negative regulation of lipid storage (GO:0010888)3.37297387
92negative regulation of phagocytosis (GO:0050765)3.37188703
93positive regulation of cholesterol efflux (GO:0010875)3.36562851
94CDP-diacylglycerol biosynthetic process (GO:0016024)3.35117530
95complement activation, alternative pathway (GO:0006957)3.34725053
96regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.32210150
97positive regulation of glomerulus development (GO:0090193)3.30835286
98monocarboxylic acid catabolic process (GO:0072329)3.30476036
99diacylglycerol metabolic process (GO:0046339)3.29151173
100positive regulation of macrophage derived foam cell differentiation (GO:0010744)3.29112490
101positive regulation of sterol transport (GO:0032373)3.27847082
102positive regulation of cholesterol transport (GO:0032376)3.27847082
103quaternary ammonium group transport (GO:0015697)3.27560659
104regulation of glycogen (starch) synthase activity (GO:2000465)3.27418522
105long-chain fatty acid transport (GO:0015909)3.27134915
106cellular response to lithium ion (GO:0071285)3.24471316
107positive regulation of glucose transport (GO:0010828)3.21762589
108alditol metabolic process (GO:0019400)3.21377482
109regulation of triglyceride catabolic process (GO:0010896)3.20911364
110succinate metabolic process (GO:0006105)3.20789267
111regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.19500454
112glomerular filtration (GO:0003094)3.19226871
113primary alcohol metabolic process (GO:0034308)3.18615257
114phosphatidic acid biosynthetic process (GO:0006654)3.18530918
115phosphatidic acid metabolic process (GO:0046473)3.18530918
116pentose-phosphate shunt (GO:0006098)3.16193952
117positive regulation of glycogen biosynthetic process (GO:0045725)3.16003394
118negative regulation of DNA biosynthetic process (GO:2000279)3.15225121
119coenzyme A metabolic process (GO:0015936)3.13079038
120L-serine transport (GO:0015825)3.11859512
121regulation of lipid storage (GO:0010883)3.11286451
122protein localization to cell surface (GO:0034394)3.10509954
123barbed-end actin filament capping (GO:0051016)3.10351288
124negative regulation of smooth muscle cell proliferation (GO:0048662)3.10175038
125NADPH regeneration (GO:0006740)3.09126536
126negative regulation of macrophage differentiation (GO:0045650)3.08478112
127positive regulation of metanephros development (GO:0072216)3.07820203
128regulation of triglyceride biosynthetic process (GO:0010866)3.06239199
129ethanol metabolic process (GO:0006067)3.06038091
130response to epinephrine (GO:0071871)3.04882288
131triglyceride homeostasis (GO:0070328)3.04521803
132acylglycerol homeostasis (GO:0055090)3.04521803
133phagocytosis, recognition (GO:0006910)3.02199639
134extracellular fibril organization (GO:0043206)3.01151160
135retinol metabolic process (GO:0042572)2.99947923
136cellular response to leptin stimulus (GO:0044320)2.99890038
137negative regulation of lipid catabolic process (GO:0050995)2.97112375
138response to vitamin E (GO:0033197)2.96723895

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse6.25099057
2CLOCK_20551151_ChIP-Seq_293T_Human4.45691146
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.89389930
4RXR_22158963_ChIP-Seq_LIVER_Mouse2.67814749
5LXR_22158963_ChIP-Seq_LIVER_Mouse2.59414946
6PPARG_20176806_ChIP-Seq_3T3-L1_Mouse2.39695308
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.30328942
8PPARA_22158963_ChIP-Seq_LIVER_Mouse2.29654822
9TP63_17297297_ChIP-ChIP_HaCaT_Human2.22889535
10GATA1_22025678_ChIP-Seq_K562_Human2.13745597
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.13634097
12NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.11084803
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.06219346
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse13.9379151
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.97171473
16PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.90802210
17ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.86388233
18CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.77344196
19ZNF263_19887448_ChIP-Seq_K562_Human1.76447338
20TBX20_22328084_ChIP-Seq_HEART_Mouse1.74747095
21TBX20_22080862_ChIP-Seq_HEART_Mouse1.74747095
22PPAR_26484153_Chip-Seq_NCI-H1993_Human1.70039568
23EP300_21415370_ChIP-Seq_HL-1_Mouse1.65699204
24TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.62270993
25BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.58551271
26ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.56206181
27ESR1_20079471_ChIP-ChIP_T-47D_Human1.43070947
28NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40847768
29NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.39145925
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.31816533
31FOXO3_23340844_ChIP-Seq_DLD1_Human1.29628319
32HIF1A_21447827_ChIP-Seq_MCF-7_Human1.28233726
33ESR2_21235772_ChIP-Seq_MCF-7_Human1.27142682
34ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25647436
35GATA2_21666600_ChIP-Seq_HMVEC_Human1.22927182
36MTF2_20144788_ChIP-Seq_MESCs_Mouse1.22113481
37CJUN_26792858_Chip-Seq_BT549_Human1.17817396
38TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17803290
39NFIB_24661679_ChIP-Seq_LUNG_Mouse1.15711122
40PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.14857874
41SOX9_24532713_ChIP-Seq_HFSC_Mouse1.12802315
42SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.12415800
43SA1_22415368_ChIP-Seq_MEFs_Mouse1.10092914
44EZH2_22144423_ChIP-Seq_EOC_Human1.09840243
45DNAJC2_21179169_ChIP-ChIP_NT2_Human1.09158068
46PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.07948656
47TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07119714
48SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.07015853
49EED_16625203_ChIP-ChIP_MESCs_Mouse1.06882441
50SMC3_22415368_ChIP-Seq_MEFs_Mouse1.05007155
51RAD21_21589869_ChIP-Seq_MESCs_Mouse1.04548175
52CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04492203
53KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04197772
54SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.04173612
55SMC1_22415368_ChIP-Seq_MEFs_Mouse1.04042221
56CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.02580743
57VDR_24787735_ChIP-Seq_THP-1_Human1.02292669
58RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99476957
59FOXA2_19822575_ChIP-Seq_HepG2_Human0.99437026
60GATA1_19941826_ChIP-Seq_K562_Human0.97214335
61ERG_21242973_ChIP-ChIP_JURKAT_Human0.95881313
62P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93955718
63TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.93105086
64SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.92822310
65JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92622823
66TET1_21490601_ChIP-Seq_MESCs_Mouse0.90898659
67EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90755566
68* CTCF_27219007_Chip-Seq_Bcells_Human0.90308731
69Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.87906062
70PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.87135586
71SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.85586128
72THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.84971135
73SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84586202
74RXR_22108803_ChIP-Seq_LS180_Human0.84580845
75STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83727698
76SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83721799
77TP53_20018659_ChIP-ChIP_R1E_Mouse0.83687891
78NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.82537860
79NRF2_20460467_ChIP-Seq_MEFs_Mouse0.82513090
80NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.82513090
81PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.81824637
82ESR1_21235772_ChIP-Seq_MCF-7_Human0.81271148
83ELK4_26923725_Chip-Seq_MESODERM_Mouse0.80884840
84WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.80682954
85EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.80549646
86EZH2_27304074_Chip-Seq_ESCs_Mouse0.79683578
87SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.79338670
88UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.78842248
89FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.78799156
90RNF2_18974828_ChIP-Seq_MESCs_Mouse0.78599049
91EZH2_18974828_ChIP-Seq_MESCs_Mouse0.78599049
92BCAT_22108803_ChIP-Seq_LS180_Human0.78435899
93DROSHA_22980978_ChIP-Seq_HELA_Human0.78418784
94TCF4_18268006_ChIP-ChIP_LS174T_Human0.78266601
95KDM2B_26808549_Chip-Seq_SUP-B15_Human0.78237239
96NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.78213059
97* SMC4_20622854_ChIP-Seq_HELA_Human0.76185764
98GATA2_19941826_ChIP-Seq_K562_Human0.75512991
99* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.75183074
100ELK3_25401928_ChIP-Seq_HUVEC_Human0.74625233
101SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73228031
102PIAS1_25552417_ChIP-Seq_VCAP_Human0.73016334
103KDM2B_26808549_Chip-Seq_K562_Human0.71955099
104BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.71889410
105RNF2_27304074_Chip-Seq_ESCs_Mouse0.71794489
106KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.71475697
107KLF4_19829295_ChIP-Seq_ESCs_Human0.69919535
108MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.69816007
109EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.69735901
110NR3C1_23031785_ChIP-Seq_PC12_Mouse0.69066190
111EZH2_27294783_Chip-Seq_ESCs_Mouse0.68917510
112CBP_21632823_ChIP-Seq_H3396_Human0.68809447
113RUNX1_27514584_Chip-Seq_MCF-7_Human0.68707073
114MYC_27129775_Chip-Seq_CORNEA_Mouse0.67837274
115TP53_23651856_ChIP-Seq_MEFs_Mouse0.67790016
116GATA3_24758297_ChIP-Seq_MCF-7_Human0.67605136
117WT1_25993318_ChIP-Seq_PODOCYTE_Human0.67206416
118SMAD_19615063_ChIP-ChIP_OVARY_Human0.66859217
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.66479858
120SOX2_20726797_ChIP-Seq_SW620_Human0.66197427
121ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.66123761
122RACK7_27058665_Chip-Seq_MCF-7_Human0.65642760
123AHR_22903824_ChIP-Seq_MCF-7_Human0.65297059
124PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.64415978
125* LXR_22292898_ChIP-Seq_THP-1_Human0.63629685
126ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.63547568
127SALL4_18804426_ChIP-ChIP_XEN_Mouse0.63091615
128SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.61271738
129GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.61179273
130CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.61128491
131* TP63_22573176_ChIP-Seq_HFKS_Human0.60621127
132ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.60016019
133ISL1_27105846_Chip-Seq_CPCs_Mouse0.59859594
134KDM2B_26808549_Chip-Seq_DND41_Human0.59637788

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005670_abnormal_white_adipose7.80175165
2MP0005666_abnormal_adipose_tissue5.24186982
3MP0004130_abnormal_muscle_cell4.89038340
4MP0002837_dystrophic_cardiac_calcinosis4.41709718
5MP0008438_abnormal_cutaneous_collagen4.33648023
6MP0004185_abnormal_adipocyte_glucose4.32651162
7MP0005375_adipose_tissue_phenotype3.95377707
8MP0000013_abnormal_adipose_tissue3.24793172
9MP0005275_abnormal_skin_tensile2.89120335
10MP0002971_abnormal_brown_adipose2.85058386
11MP0000003_abnormal_adipose_tissue2.77555376
12MP0002876_abnormal_thyroid_physiology2.70977693
13MP0009115_abnormal_fat_cell2.55702275
14MP0010329_abnormal_lipoprotein_level2.51096846
15MP0005334_abnormal_fat_pad2.29867250
16MP0003191_abnormal_cellular_cholesterol2.27109482
17MP0000751_myopathy2.22030454
18MP0005503_abnormal_tendon_morphology2.11092142
19MP0003646_muscle_fatigue2.04769246
20MP0003705_abnormal_hypodermis_morpholog2.00529178
21MP0002970_abnormal_white_adipose1.92984411
22MP0001661_extended_life_span1.79108064
23MP0003868_abnormal_feces_composition1.78511856
24MP0002118_abnormal_lipid_homeostasis1.78411109
25MP0004272_abnormal_basement_membrane1.70208742
26MP0003959_abnormal_lean_body1.69586295
27MP0003011_delayed_dark_adaptation1.66735019
28MP0005535_abnormal_body_temperature1.64437313
29MP0004215_abnormal_myocardial_fiber1.61610930
30MP0000750_abnormal_muscle_regeneration1.51533185
31MP0003690_abnormal_glial_cell1.48848243
32MP0004087_abnormal_muscle_fiber1.46736441
33MP0003828_pulmonary_edema1.45584423
34MP0006138_congestive_heart_failure1.45525525
35MP0005620_abnormal_muscle_contractility1.43617520
36MP0008775_abnormal_heart_ventricle1.39417124
37MP0000749_muscle_degeneration1.35596009
38MP0005448_abnormal_energy_balance1.32626537
39MP0000759_abnormal_skeletal_muscle1.29002929
40MP0005330_cardiomyopathy1.28465436
41MP0004036_abnormal_muscle_relaxation1.27528790
42MP0002909_abnormal_adrenal_gland1.26951363
43MP0005452_abnormal_adipose_tissue1.25105602
44MP0004084_abnormal_cardiac_muscle1.24272532
45MP0001544_abnormal_cardiovascular_syste1.24204269
46MP0005385_cardiovascular_system_phenoty1.24204269
47MP0003186_abnormal_redox_activity1.21884153
48MP0002078_abnormal_glucose_homeostasis1.16476284
49MP0003045_fibrosis1.16201835
50MP0005365_abnormal_bile_salt1.14013339
51MP0002972_abnormal_cardiac_muscle1.13615780
52MP0003724_increased_susceptibility_to1.12582315
53MP0009780_abnormal_chondrocyte_physiolo1.11442143
54MP0000609_abnormal_liver_physiology1.10486423
55MP0003950_abnormal_plasma_membrane1.06638000
56MP0000343_altered_response_to1.05923701
57MP0010368_abnormal_lymphatic_system1.05467900
58MP0002166_altered_tumor_susceptibility1.04233536
59MP0003566_abnormal_cell_adhesion1.00092856
60MP0006036_abnormal_mitochondrial_physio0.99845827
61MP0002933_joint_inflammation0.99636798
62MP0002060_abnormal_skin_morphology0.97260126
63MP0001501_abnormal_sleep_pattern0.96838437
64MP0000767_abnormal_smooth_muscle0.94848616
65MP0002106_abnormal_muscle_physiology0.94423975
66MP0002332_abnormal_exercise_endurance0.94238446
67MP0001727_abnormal_embryo_implantation0.94100941
68MP0002254_reproductive_system_inflammat0.93063060
69MP0005647_abnormal_sex_gland0.92797075
70MP0002108_abnormal_muscle_morphology0.88624048
71MP0004147_increased_porphyrin_level0.87750031
72MP0010630_abnormal_cardiac_muscle0.86556496
73MP0002269_muscular_atrophy0.86151786
74MP0005369_muscle_phenotype0.82614196
75MP0001881_abnormal_mammary_gland0.82076895
76MP0002796_impaired_skin_barrier0.81904527
77MP0003221_abnormal_cardiomyocyte_apopto0.81341904
78MP0008961_abnormal_basal_metabolism0.74594165
79MP0005319_abnormal_enzyme/_coenzyme0.73829711
80MP0000747_muscle_weakness0.73656556
81MP0003948_abnormal_gas_homeostasis0.73398154
82MP0000858_altered_metastatic_potential0.73119304
83MP0002006_tumorigenesis0.72583254
84MP0005584_abnormal_enzyme/coenzyme_acti0.72299860
85MP0005379_endocrine/exocrine_gland_phen0.71419163
86MP0002139_abnormal_hepatobiliary_system0.71137087
87MP0004484_altered_response_of0.71080892
88MP0004145_abnormal_muscle_electrophysio0.71061888
89MP0001756_abnormal_urination0.70909970
90MP0002168_other_aberrant_phenotype0.69235371
91MP0002638_abnormal_pupillary_reflex0.68640372
92MP0002295_abnormal_pulmonary_circulatio0.67209059
93MP0001879_abnormal_lymphatic_vessel0.66086720
94MP0006276_abnormal_autonomic_nervous0.63768123
95MP0003953_abnormal_hormone_level0.63763546
96MP0001764_abnormal_homeostasis0.62898782
97MP0003279_aneurysm0.62615344
98MP0001958_emphysema0.62401619
99MP0004858_abnormal_nervous_system0.62356424
100MP0000230_abnormal_systemic_arterial0.61626489
101MP0005266_abnormal_metabolism0.61131997
102MP0005164_abnormal_response_to0.60217935
103MP0003075_altered_response_to0.57219309
104MP0009643_abnormal_urine_homeostasis0.54713016
105MP0003091_abnormal_cell_migration0.53543863
106MP0005508_abnormal_skeleton_morphology0.53533025
107MP0002128_abnormal_blood_circulation0.53440959
108MP0005165_increased_susceptibility_to0.50961813
109MP0003879_abnormal_hair_cell0.50397175
110MP0005332_abnormal_amino_acid0.50045232
111MP0009672_abnormal_birth_weight0.49511722
112MP0000249_abnormal_blood_vessel0.49236049
113MP0005595_abnormal_vascular_smooth0.47260740
114MP0002133_abnormal_respiratory_system0.46280939
115MP0005388_respiratory_system_phenotype0.46280939
116MP0003137_abnormal_impulse_conducting0.46213103
117MP0005167_abnormal_blood-brain_barrier0.45625677

Predicted human phenotypes

RankGene SetZ-score
1Oligomenorrhea (HP:0000876)7.66792033
2Acanthosis nigricans (HP:0000956)6.37546053
3Hypertriglyceridemia (HP:0002155)5.40988975
4Difficulty running (HP:0009046)4.97918888
5Increased connective tissue (HP:0009025)4.90639603
6Myoglobinuria (HP:0002913)4.81559442
7Hyperglycinuria (HP:0003108)4.62630782
8Muscle fiber splitting (HP:0003555)4.48775587
9Insulin-resistant diabetes mellitus (HP:0000831)4.22807165
10Type 1 muscle fiber predominance (HP:0003803)3.90067898
11Abnormality of serine family amino acid metabolism (HP:0010894)3.76032993
12Abnormality of glycine metabolism (HP:0010895)3.76032993
13Rhabdomyolysis (HP:0003201)3.74820840
14Complement deficiency (HP:0004431)3.67575044
15Hyporeflexia of lower limbs (HP:0002600)3.59756098
16Exercise-induced myalgia (HP:0003738)3.54422967
17Lipoatrophy (HP:0100578)3.52111261
18Increased variability in muscle fiber diameter (HP:0003557)3.44544548
19Hypoalphalipoproteinemia (HP:0003233)3.27202688
20Abnormality of fatty-acid metabolism (HP:0004359)3.19740107
21Reduced subcutaneous adipose tissue (HP:0003758)3.19623486
22Broad metatarsal (HP:0001783)3.17731336
23Insulin resistance (HP:0000855)3.16995136
24Right ventricular cardiomyopathy (HP:0011663)3.16848278
25Long foot (HP:0001833)3.14440831
26Back pain (HP:0003418)3.14393604
27Pigmentary retinal degeneration (HP:0001146)3.13969190
28Hypoglycemic coma (HP:0001325)3.13687420
29Frequent falls (HP:0002359)3.13504877
30Ketoacidosis (HP:0001993)3.12701448
31Abnormality of skeletal muscle fiber size (HP:0012084)3.06637545
32Hypercortisolism (HP:0001578)2.99095744
33Bone cyst (HP:0012062)2.95059838
34Facial diplegia (HP:0001349)2.92936281
35Abnormal eating behavior (HP:0100738)2.90473515
36Vertebral compression fractures (HP:0002953)2.89063168
37Hemorrhage of the eye (HP:0011885)2.88185049
38Ketosis (HP:0001946)2.87779778
39Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.87374238
40Ectopia lentis (HP:0001083)2.85821939
41Cerebral aneurysm (HP:0004944)2.85364764
42Polycythemia (HP:0001901)2.82005386
43Increased muscle lipid content (HP:0009058)2.79487162
44Axonal loss (HP:0003447)2.76270146
45Sudden death (HP:0001699)2.76194063
46Striae distensae (HP:0001065)2.74388037
47Myotonia (HP:0002486)2.74066626
48Subcapsular cataract (HP:0000523)2.73643483
49Spinal rigidity (HP:0003306)2.73258772
50Multiple enchondromatosis (HP:0005701)2.70601503
51Ankle contracture (HP:0006466)2.70236258
52Growth hormone excess (HP:0000845)2.69704984
53Proximal amyotrophy (HP:0007126)2.69109766
54Calf muscle hypertrophy (HP:0008981)2.64352392
55Hydroxyprolinuria (HP:0003080)2.63852523
56Abnormality of proline metabolism (HP:0010907)2.63852523
57Large hands (HP:0001176)2.60405950
58Abnormality of complement system (HP:0005339)2.55686830
59Muscle stiffness (HP:0003552)2.55629196
60Ventricular tachycardia (HP:0004756)2.52819387
61Hyperthyroidism (HP:0000836)2.52234447
62Epidermoid cyst (HP:0200040)2.50235834
63Muscle hypertrophy of the lower extremities (HP:0008968)2.47848634
64Hypercholesterolemia (HP:0003124)2.47692020
65Myocardial infarction (HP:0001658)2.47194439
66Shallow orbits (HP:0000586)2.46282564
67Abnormality of dicarboxylic acid metabolism (HP:0010995)2.44494364
68Dicarboxylic aciduria (HP:0003215)2.44494364
69Testicular atrophy (HP:0000029)2.44377655
70Exercise-induced muscle cramps (HP:0003710)2.41548390
71Lymphangioma (HP:0100764)2.36545390
72Cervical subluxation (HP:0003308)2.36416661
73Gowers sign (HP:0003391)2.35670679
74Infantile muscular hypotonia (HP:0008947)2.35418154
75Skin nodule (HP:0200036)2.32986111
76Neck muscle weakness (HP:0000467)2.31825049
77Systemic lupus erythematosus (HP:0002725)2.31310162
78Easy fatigability (HP:0003388)2.27762221
79Hyperammonemia (HP:0001987)2.27567808
80Rimmed vacuoles (HP:0003805)2.26125930
81Prenatal maternal abnormality (HP:0002686)2.24966985
82Hyperglycemia (HP:0003074)2.24566916
83Colitis (HP:0002583)2.21757612
84Toxemia of pregnancy (HP:0100603)2.21332536
85Thyroid-stimulating hormone excess (HP:0002925)2.20552136
86Palpitations (HP:0001962)2.20512840
87Nausea (HP:0002018)2.20306259
88Hyperlipoproteinemia (HP:0010980)2.19506405
89Wormian bones (HP:0002645)2.18924516
90Mitral valve prolapse (HP:0001634)2.14190522
91Slender build (HP:0001533)2.13897314
92Hyperpituitarism (HP:0010514)2.13004544
93Hyperglycinemia (HP:0002154)2.12891948
94Abnormal cartilage morphology (HP:0002763)2.11618418
95Dilatation of the ascending aorta (HP:0005111)2.11156713
96Pulmonary artery stenosis (HP:0004415)2.10951686
97Ileus (HP:0002595)2.10924679
98Dilated cardiomyopathy (HP:0001644)2.10089709
99Atrioventricular block (HP:0001678)2.10029379
100Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.07827242
101Vascular tortuosity (HP:0004948)2.07242950
102Scapular winging (HP:0003691)2.07226277
103Premature rupture of membranes (HP:0001788)2.07210168
104Xanthomatosis (HP:0000991)2.05659529
105Foot dorsiflexor weakness (HP:0009027)2.05605210
106Accelerated skeletal maturation (HP:0005616)2.04111699
107Bulbar palsy (HP:0001283)1.99786692
108Abnormality of the calf musculature (HP:0001430)1.98862669
109Mildly elevated creatine phosphokinase (HP:0008180)1.98547181
110Decreased subcutaneous fat (HP:0001002)1.98411329
111Hypoplasia of the iris (HP:0007676)1.93909067
112Atrial fibrillation (HP:0005110)1.93408367
113Follicular hyperkeratosis (HP:0007502)1.93349082
114Esophageal varix (HP:0002040)1.92689055
115Joint hemorrhage (HP:0005261)1.92560948
116Muscle fiber inclusion bodies (HP:0100299)1.92243457
117Abnormal hemoglobin (HP:0011902)1.91854931
118Asymmetric septal hypertrophy (HP:0001670)1.91558549
119Venous abnormality (HP:0002624)1.91456688
120Pancreatitis (HP:0001733)1.91149611
121Abnormality of the foot musculature (HP:0001436)1.90774516
122Aortic aneurysm (HP:0004942)1.88332181
123Enlarged penis (HP:0000040)1.88059018
124Tetraparesis (HP:0002273)1.86769609
125Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.86118762
126Prominent supraorbital ridges (HP:0000336)1.86112079
127Rectal prolapse (HP:0002035)1.85266229
128Distal lower limb amyotrophy (HP:0008944)1.83517468
129Soft skin (HP:0000977)1.83512659
130Increased serum pyruvate (HP:0003542)1.83028097
131Conjunctival hamartoma (HP:0100780)1.82645697
132Aneurysm (HP:0002617)1.82573917
133Obstructive sleep apnea (HP:0002870)1.81545886
134Aortic dissection (HP:0002647)1.80935107
135Abnormal atrioventricular conduction (HP:0005150)1.80443347
136Polyphagia (HP:0002591)1.80423886
137Stridor (HP:0010307)1.78621443
138Nemaline bodies (HP:0003798)1.78550436
139EMG: myopathic abnormalities (HP:0003458)1.78272170
140Protrusio acetabuli (HP:0003179)1.78110232
141Amyloidosis (HP:0011034)1.77845541
142Polar cataract (HP:0010696)1.77349312

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CAMK1D5.80992586
2TRIB35.41938207
3CAMK1G4.30195576
4SIK14.02976666
5BCKDK3.74900337
6LMTK23.09832348
7PDK32.93125886
8PDK42.93125886
9TTN2.73354838
10RIPK12.58412249
11PHKG22.13678459
12PHKG12.13678459
13TESK12.10774104
14MST1R2.05938534
15OBSCN2.00614544
16INSRR1.92251880
17PRKAA21.86832218
18MAPK41.75424950
19PDK21.74346387
20PIK3CA1.61349227
21ERN11.54463855
22FGFR21.51459043
23PDGFRA1.45018711
24FGFR31.45008504
25MYLK1.36898150
26EPHA31.34829956
27MAP3K131.34225747
28FRK1.28457162
29TIE11.26079908
30GRK51.17043142
31PRKD31.16662390
32RIPK41.14112751
33PKN21.11595950
34MOS1.09955904
35CDK91.05959322
36PRKAA11.05795913
37LATS11.02000687
38DDR21.01033735
39JAK10.98483686
40TGFBR20.98366052
41PINK10.98015471
42NLK0.96957204
43KIT0.96649627
44EPHB20.95271473
45MAP3K60.94875278
46ARAF0.94045782
47MAPK70.92542856
48DMPK0.91927523
49PRPF4B0.91828553
50CDK60.87746551
51MET0.86531188
52MAP2K10.83459891
53PRKCH0.81964359
54FGFR40.81789217
55PDPK10.80846324
56KDR0.80778064
57NEK90.80243429
58TYK20.78810570
59FER0.76971461
60CDC42BPA0.75572245
61FES0.74785942
62ILK0.74294065
63PRKD10.73942504
64PRKG10.72316793
65MTOR0.70121706
66MAP2K30.69065592
67PTK20.67918606
68ADRBK10.67424024
69JAK20.65274920
70STK38L0.65090744
71PTK2B0.62618596
72PRKACG0.61797105
73MAPK120.61413906
74PDK10.61197798
75PDGFRB0.60990703
76CAMK10.59488731
77RET0.58438587
78PKN10.57935430
79KSR20.57855775
80MAPK30.55907134
81MARK10.53264715
82LATS20.52714197
83MAPK110.52439028
84PRKACB0.51206832
85TBK10.50376589
86IRAK30.48968392
87IGF1R0.48892913
88PIK3CG0.48208280
89MAPKAPK30.48087078
90GSK3A0.46813952
91CAMKK20.46642186
92MAP3K10.45977980
93MAP3K70.45716500
94ZAP700.45666014
95EEF2K0.45032592
96HIPK20.43192201
97PAK20.42640570
98MARK20.42086385
99CSK0.41344467
100PAK40.41148820
101TRPM70.40757270
102FGFR10.40578950
103EPHB10.38028081
104MAP2K40.36678912
105BLK0.36106702
106ABL10.35966832
107PRKD20.35965273
108ICK0.35682918
109INSR0.35341006
110SGK20.34183534
111RPS6KA20.34075018
112FLT30.34031687
113MAP3K30.33596849
114CDK40.32794500
115MAPK10.32189421
116DAPK20.31758546
117ROCK10.30776014
118STK110.30638408
119PRKG20.29858831
120BMX0.29811299
121CSF1R0.28890086
122PTK60.28866983
123SRC0.28787825
124EIF2AK20.27275404
125SGK30.24510602
126JAK30.24454417
127RPS6KB10.23849035
128PAK30.22777457
129STK380.21507147
130RPS6KA30.21315693
131ABL20.21161805
132PRKACA0.19727445
133LRRK20.19591312
134NEK10.15887125
135AKT20.15852535

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.52608839
2Propanoate metabolism_Homo sapiens_hsa006404.36309154
3Regulation of lipolysis in adipocytes_Homo sapiens_hsa049234.25703253
4PPAR signaling pathway_Homo sapiens_hsa033204.25410470
5Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.91984832
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.34743314
7Fatty acid metabolism_Homo sapiens_hsa012123.33967104
82-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.97105885
9Fatty acid degradation_Homo sapiens_hsa000712.92568588
10Glycerolipid metabolism_Homo sapiens_hsa005612.72980124
11Adipocytokine signaling pathway_Homo sapiens_hsa049202.31174818
12Pyruvate metabolism_Homo sapiens_hsa006202.23073937
13AMPK signaling pathway_Homo sapiens_hsa041522.09600875
14Histidine metabolism_Homo sapiens_hsa003401.95826919
15beta-Alanine metabolism_Homo sapiens_hsa004101.85334450
16Carbon metabolism_Homo sapiens_hsa012001.85114239
17Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.72117961
18Fat digestion and absorption_Homo sapiens_hsa049751.67756738
19Caffeine metabolism_Homo sapiens_hsa002321.61349473
20Nitrogen metabolism_Homo sapiens_hsa009101.55296086
21Insulin resistance_Homo sapiens_hsa049311.48587832
22Insulin signaling pathway_Homo sapiens_hsa049101.42092469
23Peroxisome_Homo sapiens_hsa041461.41246312
24Butanoate metabolism_Homo sapiens_hsa006501.32933066
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.28537902
26Phenylalanine metabolism_Homo sapiens_hsa003601.26723393
27Vitamin B6 metabolism_Homo sapiens_hsa007501.19915433
28Glucagon signaling pathway_Homo sapiens_hsa049221.15125541
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.10489445
30Tyrosine metabolism_Homo sapiens_hsa003501.08846431
31Fatty acid elongation_Homo sapiens_hsa000621.07262114
32Longevity regulating pathway - mammal_Homo sapiens_hsa042110.98896211
33ECM-receptor interaction_Homo sapiens_hsa045120.98352240
34Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97578496
35Staphylococcus aureus infection_Homo sapiens_hsa051500.96119250
36Malaria_Homo sapiens_hsa051440.95873166
37Renin secretion_Homo sapiens_hsa049240.94365078
38Tryptophan metabolism_Homo sapiens_hsa003800.88555710
39Type II diabetes mellitus_Homo sapiens_hsa049300.86462512
40Dilated cardiomyopathy_Homo sapiens_hsa054140.83443209
41Sulfur relay system_Homo sapiens_hsa041220.82284339
42Pentose phosphate pathway_Homo sapiens_hsa000300.77360413
43Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74442289
44Arginine biosynthesis_Homo sapiens_hsa002200.72585973
45Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72117675
46Glycerophospholipid metabolism_Homo sapiens_hsa005640.71941194
47Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71368255
48Starch and sucrose metabolism_Homo sapiens_hsa005000.70641844
49Focal adhesion_Homo sapiens_hsa045100.70098894
50Notch signaling pathway_Homo sapiens_hsa043300.68036333
51Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66276795
52ABC transporters_Homo sapiens_hsa020100.66276439
53Glycosaminoglycan degradation_Homo sapiens_hsa005310.64078791
54Protein digestion and absorption_Homo sapiens_hsa049740.63211433
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.62789762
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61924321
57Dorso-ventral axis formation_Homo sapiens_hsa043200.60339807
58Biosynthesis of amino acids_Homo sapiens_hsa012300.59423336
59Retinol metabolism_Homo sapiens_hsa008300.58710498
60Viral myocarditis_Homo sapiens_hsa054160.53157537
61Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.52247486
62Lysine degradation_Homo sapiens_hsa003100.51630205
63cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50835822
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49416446
65Complement and coagulation cascades_Homo sapiens_hsa046100.47658200
66Renin-angiotensin system_Homo sapiens_hsa046140.47356708
67Circadian rhythm_Homo sapiens_hsa047100.46286297
68mTOR signaling pathway_Homo sapiens_hsa041500.44569729
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44414682
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44034078
71HIF-1 signaling pathway_Homo sapiens_hsa040660.43714166
72Arginine and proline metabolism_Homo sapiens_hsa003300.43129666
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.43067717
74Fructose and mannose metabolism_Homo sapiens_hsa000510.42697248
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.39978040
76Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.39652977
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37633861
78Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.37486311
79cAMP signaling pathway_Homo sapiens_hsa040240.36453224
80Cardiac muscle contraction_Homo sapiens_hsa042600.34297663
81Acute myeloid leukemia_Homo sapiens_hsa052210.32669380
82Amoebiasis_Homo sapiens_hsa051460.32239789
83Jak-STAT signaling pathway_Homo sapiens_hsa046300.31264055
84Vitamin digestion and absorption_Homo sapiens_hsa049770.29832732
85Proteoglycans in cancer_Homo sapiens_hsa052050.28820268
86Glutathione metabolism_Homo sapiens_hsa004800.26538937
87GnRH signaling pathway_Homo sapiens_hsa049120.24967911
88Melanogenesis_Homo sapiens_hsa049160.24235997
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23928802
90Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.23908090
91Chemical carcinogenesis_Homo sapiens_hsa052040.22671715
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.22599568
93Autoimmune thyroid disease_Homo sapiens_hsa053200.21925483
94Rap1 signaling pathway_Homo sapiens_hsa040150.21246653
95Small cell lung cancer_Homo sapiens_hsa052220.20635011
96Morphine addiction_Homo sapiens_hsa050320.20214804
97Linoleic acid metabolism_Homo sapiens_hsa005910.19376169
98Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.19101482
99PI3K-Akt signaling pathway_Homo sapiens_hsa041510.18943642
100AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.18906248
101Platelet activation_Homo sapiens_hsa046110.18627974
102Estrogen signaling pathway_Homo sapiens_hsa049150.17801163
103Salivary secretion_Homo sapiens_hsa049700.17599790
104Gap junction_Homo sapiens_hsa045400.16991338
105Adherens junction_Homo sapiens_hsa045200.16982761
106Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.15904735
107Folate biosynthesis_Homo sapiens_hsa007900.15540310
108Ovarian steroidogenesis_Homo sapiens_hsa049130.14934859
109Pathways in cancer_Homo sapiens_hsa052000.14714243
110Sulfur metabolism_Homo sapiens_hsa009200.13694148
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.12940897
112Alzheimers disease_Homo sapiens_hsa050100.12771080
113Other glycan degradation_Homo sapiens_hsa005110.12732776
114Tight junction_Homo sapiens_hsa045300.12666011
115Leukocyte transendothelial migration_Homo sapiens_hsa046700.12061515
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.11877828
117Toxoplasmosis_Homo sapiens_hsa051450.11663089
118FoxO signaling pathway_Homo sapiens_hsa040680.11212628
119Metabolic pathways_Homo sapiens_hsa011000.11022850
120Oxytocin signaling pathway_Homo sapiens_hsa049210.10905094
121Arachidonic acid metabolism_Homo sapiens_hsa005900.09349474
122Bile secretion_Homo sapiens_hsa049760.09214372
123Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09059407
124Calcium signaling pathway_Homo sapiens_hsa040200.09040212
125Parkinsons disease_Homo sapiens_hsa050120.08855952
126Gastric acid secretion_Homo sapiens_hsa049710.07507184
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.07466287
128Thyroid hormone synthesis_Homo sapiens_hsa049180.07449150
129Pentose and glucuronate interconversions_Homo sapiens_hsa000400.06947359

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