Rank | Gene Set | Z-score |
---|---|---|
1 | Golgi transport vesicle coating (GO:0048200) | 5.33724887 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 5.33724887 |
3 | protein retention in ER lumen (GO:0006621) | 5.13233756 |
4 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 5.11451137 |
5 | peptidyl-proline hydroxylation (GO:0019511) | 4.49869819 |
6 | chondrocyte proliferation (GO:0035988) | 3.99822474 |
7 | protein hydroxylation (GO:0018126) | 3.99191285 |
8 | axon ensheathment in central nervous system (GO:0032291) | 3.97198920 |
9 | central nervous system myelination (GO:0022010) | 3.97198920 |
10 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.96690842 |
11 | hemidesmosome assembly (GO:0031581) | 3.74023761 |
12 | wound healing, spreading of epidermal cells (GO:0035313) | 3.66123636 |
13 | regulation of plasminogen activation (GO:0010755) | 3.65105496 |
14 | basement membrane organization (GO:0071711) | 3.58985505 |
15 | cell-substrate junction assembly (GO:0007044) | 3.56388599 |
16 | collagen fibril organization (GO:0030199) | 3.55163570 |
17 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.42765165 |
18 | extracellular fibril organization (GO:0043206) | 3.38182780 |
19 | barbed-end actin filament capping (GO:0051016) | 3.37273605 |
20 | protein maturation by protein folding (GO:0022417) | 3.36989313 |
21 | substrate-dependent cell migration (GO:0006929) | 3.36956189 |
22 | adhesion of symbiont to host cell (GO:0044650) | 3.35340839 |
23 | virion attachment to host cell (GO:0019062) | 3.35340839 |
24 | negative regulation of fibrinolysis (GO:0051918) | 3.34323379 |
25 | apoptotic cell clearance (GO:0043277) | 3.33997287 |
26 | axon ensheathment (GO:0008366) | 3.32996923 |
27 | ensheathment of neurons (GO:0007272) | 3.32996923 |
28 | import into cell (GO:0098657) | 3.31282828 |
29 | hyaluronan catabolic process (GO:0030214) | 3.30900758 |
30 | protein heterotrimerization (GO:0070208) | 3.30271641 |
31 | keratan sulfate catabolic process (GO:0042340) | 3.28627584 |
32 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.28501491 |
33 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.26937304 |
34 | adhesion of symbiont to host (GO:0044406) | 3.26934572 |
35 | low-density lipoprotein particle clearance (GO:0034383) | 3.26884066 |
36 | response to lipoprotein particle (GO:0055094) | 3.24527046 |
37 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.24017481 |
38 | myelination (GO:0042552) | 3.23772927 |
39 | glomerular filtration (GO:0003094) | 3.20160702 |
40 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 3.17730281 |
41 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.16401973 |
42 | endothelial cell morphogenesis (GO:0001886) | 3.16363764 |
43 | collagen metabolic process (GO:0032963) | 3.16123620 |
44 | collagen catabolic process (GO:0030574) | 3.14755705 |
45 | fatty acid elongation (GO:0030497) | 3.14238488 |
46 | creatine metabolic process (GO:0006600) | 3.11436592 |
47 | regulation of early endosome to late endosome transport (GO:2000641) | 3.10456236 |
48 | type B pancreatic cell proliferation (GO:0044342) | 3.04491711 |
49 | regulation of extracellular matrix disassembly (GO:0010715) | 3.03182159 |
50 | cell migration involved in heart development (GO:0060973) | 3.00627974 |
51 | skin morphogenesis (GO:0043589) | 3.00524314 |
52 | regulation of sequestering of triglyceride (GO:0010889) | 2.99471753 |
53 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.96850527 |
54 | proline biosynthetic process (GO:0006561) | 2.93993971 |
55 | positive regulation of extracellular matrix organization (GO:1903055) | 2.93355551 |
56 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.92833695 |
57 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.91385650 |
58 | adherens junction assembly (GO:0034333) | 2.90847001 |
59 | mesodermal cell differentiation (GO:0048333) | 2.90794957 |
60 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.90227104 |
61 | endodermal cell differentiation (GO:0035987) | 2.89829545 |
62 | endocardial cushion development (GO:0003197) | 2.89084116 |
63 | multicellular organismal catabolic process (GO:0044243) | 2.88858882 |
64 | venous blood vessel morphogenesis (GO:0048845) | 2.88221861 |
65 | fibril organization (GO:0097435) | 2.88141210 |
66 | negative regulation of fatty acid transport (GO:2000192) | 2.86493816 |
67 | COPII vesicle coating (GO:0048208) | 2.86298489 |
68 | pinocytosis (GO:0006907) | 2.86140166 |
69 | plasma lipoprotein particle clearance (GO:0034381) | 2.85741170 |
70 | wound healing, spreading of cells (GO:0044319) | 2.85707968 |
71 | myelination in peripheral nervous system (GO:0022011) | 2.85304171 |
72 | peripheral nervous system axon ensheathment (GO:0032292) | 2.85304171 |
73 | positive regulation of osteoblast proliferation (GO:0033690) | 2.83869544 |
74 | stress fiber assembly (GO:0043149) | 2.83488130 |
75 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.82496177 |
76 | glomerular basement membrane development (GO:0032836) | 2.82048314 |
77 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.81631219 |
78 | multicellular organismal metabolic process (GO:0044236) | 2.80103364 |
79 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.79904052 |
80 | cell-substrate adherens junction assembly (GO:0007045) | 2.79324822 |
81 | focal adhesion assembly (GO:0048041) | 2.79324822 |
82 | renal filtration (GO:0097205) | 2.77885694 |
83 | vesicle coating (GO:0006901) | 2.76955388 |
84 | positive regulation of nuclease activity (GO:0032075) | 2.75984421 |
85 | cell adhesion mediated by integrin (GO:0033627) | 2.75381949 |
86 | embryo implantation (GO:0007566) | 2.74008598 |
87 | blood vessel maturation (GO:0001955) | 2.73642770 |
88 | regulation of lipoprotein metabolic process (GO:0050746) | 2.72740705 |
89 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.71487854 |
90 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.71080717 |
91 | extracellular matrix disassembly (GO:0022617) | 2.69285993 |
92 | platelet degranulation (GO:0002576) | 2.68567017 |
93 | positive regulation of p38MAPK cascade (GO:1900745) | 2.68004778 |
94 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.67544561 |
95 | protein carboxylation (GO:0018214) | 2.67544561 |
96 | regulation of fibrinolysis (GO:0051917) | 2.65710949 |
97 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.65504919 |
98 | negative regulation of protein localization to cell surface (GO:2000009) | 2.65438031 |
99 | complement activation, alternative pathway (GO:0006957) | 2.65343774 |
100 | membrane raft organization (GO:0031579) | 2.65094751 |
101 | positive regulation of collagen biosynthetic process (GO:0032967) | 2.63641812 |
102 | protein localization to endosome (GO:0036010) | 2.62713254 |
103 | bone trabecula formation (GO:0060346) | 2.62212539 |
104 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.61922232 |
105 | cochlea morphogenesis (GO:0090103) | 2.61587808 |
106 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.61504381 |
107 | myelin maintenance (GO:0043217) | 2.61492343 |
108 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.60819811 |
109 | epithelial cell-cell adhesion (GO:0090136) | 2.60669557 |
110 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.60661162 |
111 | tooth mineralization (GO:0034505) | 2.57978371 |
112 | craniofacial suture morphogenesis (GO:0097094) | 2.57624202 |
113 | regulation of cholesterol storage (GO:0010885) | 2.55480510 |
114 | hypotonic response (GO:0006971) | 2.55435435 |
115 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.55346787 |
116 | alpha-linolenic acid metabolic process (GO:0036109) | 2.54617097 |
117 | cardiac myofibril assembly (GO:0055003) | 2.54066053 |
118 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.53680246 |
119 | endothelial cell chemotaxis (GO:0035767) | 2.52533995 |
120 | muscle cell migration (GO:0014812) | 2.52108755 |
121 | blood vessel endothelial cell migration (GO:0043534) | 2.51742124 |
122 | positive regulation by symbiont of host defense response (GO:0052509) | 2.51381376 |
123 | modulation by symbiont of host defense response (GO:0052031) | 2.51381376 |
124 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.51381376 |
125 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.51381376 |
126 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.51381376 |
127 | modulation by symbiont of host immune response (GO:0052553) | 2.51381376 |
128 | iron ion import (GO:0097286) | 2.50040576 |
129 | extracellular matrix assembly (GO:0085029) | 2.49161901 |
130 | kidney mesenchyme development (GO:0072074) | 2.49056284 |
131 | positive regulation of receptor recycling (GO:0001921) | 2.48765100 |
132 | positive regulation of endothelial cell migration (GO:0010595) | 2.48689953 |
133 | actin filament depolymerization (GO:0030042) | 2.46864551 |
134 | regulation of p38MAPK cascade (GO:1900744) | 2.44832031 |
135 | L-phenylalanine catabolic process (GO:0006559) | 2.44180142 |
136 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.44180142 |
137 | regulation of complement activation (GO:0030449) | 2.43854787 |
138 | lymphangiogenesis (GO:0001946) | 2.42423303 |
139 | trabecula formation (GO:0060343) | 2.41788091 |
140 | mannose metabolic process (GO:0006013) | 2.40480808 |
141 | response to methylmercury (GO:0051597) | 2.40420067 |
142 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.40361985 |
143 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.40179845 |
144 | semaphorin-plexin signaling pathway (GO:0071526) | 2.39268561 |
145 | 4-hydroxyproline metabolic process (GO:0019471) | 2.38120701 |
146 | regulation of protein activation cascade (GO:2000257) | 2.38089902 |
147 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.35799542 |
148 | myofibril assembly (GO:0030239) | 2.35705216 |
149 | heart trabecula formation (GO:0060347) | 2.34365794 |
150 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.34283005 |
151 | fibrinolysis (GO:0042730) | 2.34215824 |
152 | cortical actin cytoskeleton organization (GO:0030866) | 2.33136132 |
153 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.32321686 |
154 | amyloid precursor protein catabolic process (GO:0042987) | 2.32220952 |
155 | astrocyte development (GO:0014002) | 2.32168613 |
156 | lymph vessel development (GO:0001945) | 2.31193471 |
157 | cholesterol biosynthetic process (GO:0006695) | 2.31134824 |
158 | amyloid precursor protein metabolic process (GO:0042982) | 2.30876882 |
159 | heme transport (GO:0015886) | 2.29861905 |
160 | dermatan sulfate biosynthetic process (GO:0030208) | 2.28603152 |
161 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.27701311 |
162 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 2.27254017 |
163 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.25688563 |
164 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.25386249 |
165 | response to laminar fluid shear stress (GO:0034616) | 2.24664832 |
166 | fatty acid beta-oxidation (GO:0006635) | 2.24313574 |
167 | * extracellular matrix organization (GO:0030198) | 2.23736472 |
168 | * extracellular structure organization (GO:0043062) | 2.22728708 |
169 | opsonization (GO:0008228) | 2.22598239 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.56537922 |
2 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.78602695 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.65292354 |
4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.97423455 |
5 | * PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.80442231 |
6 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.74222332 |
7 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.72277024 |
8 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.55433028 |
9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.51566807 |
10 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.50202826 |
11 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.44215890 |
12 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.32168779 |
13 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.30499810 |
14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.29394084 |
15 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.17480017 |
16 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.00933062 |
17 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.96913951 |
18 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.94389464 |
19 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.87937067 |
20 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.87687368 |
21 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.84539940 |
22 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.84539940 |
23 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.84076079 |
24 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.83385337 |
25 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.81110084 |
26 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.79937989 |
27 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.79812156 |
28 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.78577526 |
29 | CJUN_26792858_Chip-Seq_BT549_Human | 1.77799150 |
30 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.71233073 |
31 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.70506712 |
32 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.70506712 |
33 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.70398287 |
34 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.69654568 |
35 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.68519760 |
36 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.67833690 |
37 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.62355351 |
38 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.59281124 |
39 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.58604243 |
40 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.55544560 |
41 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.55045455 |
42 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.53642818 |
43 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.52542708 |
44 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.52524723 |
45 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51486465 |
46 | ATF3_27146783_Chip-Seq_COLON_Human | 1.51296186 |
47 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.49540474 |
48 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.48539375 |
49 | KDM2B_26808549_Chip-Seq_K562_Human | 1.47670019 |
50 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.41273123 |
51 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.41206304 |
52 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.40689011 |
53 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.38494294 |
54 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.35693573 |
55 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.35319471 |
56 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.33288377 |
57 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.32794030 |
58 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.32673679 |
59 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.32387741 |
60 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.32362652 |
61 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.30959782 |
62 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.30221543 |
63 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.29738881 |
64 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.27886893 |
65 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.27886893 |
66 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.27849927 |
67 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.27131491 |
68 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.25305594 |
69 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.24527293 |
70 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.24433420 |
71 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.24311091 |
72 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.24305361 |
73 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.24132275 |
74 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.23864117 |
75 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.23519768 |
76 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.23352275 |
77 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.22663027 |
78 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.20830018 |
79 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.19542884 |
80 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.18512275 |
81 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.18195127 |
82 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.17802870 |
83 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17337609 |
84 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.16293198 |
85 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.15780194 |
86 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.15240277 |
87 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.14534917 |
88 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.14060982 |
89 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.13413931 |
90 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.13381632 |
91 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.13371130 |
92 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.13247806 |
93 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.12220657 |
94 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.10654774 |
95 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.10062739 |
96 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.09068746 |
97 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.07480877 |
98 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.05734444 |
99 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05450470 |
100 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.04827670 |
101 | GATA1_19941826_ChIP-Seq_K562_Human | 1.03821371 |
102 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.03700284 |
103 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.03494054 |
104 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.03401582 |
105 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.02410969 |
106 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.02347548 |
107 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.01535509 |
108 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.01208252 |
109 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.98612949 |
110 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97908597 |
111 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.96719236 |
112 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.96667022 |
113 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.96187874 |
114 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96001406 |
115 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.94649112 |
116 | * EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.93795301 |
117 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 0.93435804 |
118 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.92832840 |
119 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.92716648 |
120 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.92520121 |
121 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.92036558 |
122 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 0.92003787 |
123 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.91103316 |
124 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.90728288 |
125 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.90364548 |
126 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.89978442 |
127 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.89429533 |
128 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.88886061 |
129 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.88726003 |
130 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.85487318 |
131 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.84489277 |
132 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.84489277 |
133 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.84009768 |
134 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.82967446 |
135 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.82827055 |
136 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.82629577 |
137 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.81678240 |
138 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.81558592 |
139 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.81503586 |
140 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.81242445 |
141 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.79633010 |
142 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.79408214 |
143 | TP53_16413492_ChIP-PET_HCT116_Human | 0.79306064 |
144 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.79129476 |
145 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.78115416 |
146 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.77897255 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0008438_abnormal_cutaneous_collagen | 6.17150429 |
2 | MP0005503_abnormal_tendon_morphology | 3.40956414 |
3 | MP0004272_abnormal_basement_membrane | 3.25378053 |
4 | MP0005275_abnormal_skin_tensile | 3.18888524 |
5 | MP0005058_abnormal_lysosome_morphology | 2.66459534 |
6 | MP0003950_abnormal_plasma_membrane | 2.58637404 |
7 | MP0003279_aneurysm | 2.54421070 |
8 | MP0001958_emphysema | 2.41238722 |
9 | MP0009840_abnormal_foam_cell | 2.41173291 |
10 | MP0003705_abnormal_hypodermis_morpholog | 2.35266445 |
11 | MP0010368_abnormal_lymphatic_system | 2.29758761 |
12 | MP0005171_absent_coat_pigmentation | 2.29009180 |
13 | MP0000920_abnormal_myelination | 2.28365919 |
14 | MP0010030_abnormal_orbit_morphology | 2.26989810 |
15 | MP0000751_myopathy | 2.09644308 |
16 | MP0003690_abnormal_glial_cell | 2.05811416 |
17 | MP0005670_abnormal_white_adipose | 2.03416513 |
18 | MP0002877_abnormal_melanocyte_morpholog | 2.01758853 |
19 | MP0004084_abnormal_cardiac_muscle | 1.94781957 |
20 | MP0004858_abnormal_nervous_system | 1.90853445 |
21 | MP0006054_spinal_hemorrhage | 1.88261717 |
22 | MP0003191_abnormal_cellular_cholesterol | 1.77642007 |
23 | MP0002837_dystrophic_cardiac_calcinosis | 1.67817705 |
24 | MP0005623_abnormal_meninges_morphology | 1.67310444 |
25 | MP0003566_abnormal_cell_adhesion | 1.65844399 |
26 | MP0001849_ear_inflammation | 1.64334200 |
27 | MP0002295_abnormal_pulmonary_circulatio | 1.63780250 |
28 | MP0009384_cardiac_valve_regurgitation | 1.60924997 |
29 | MP0001879_abnormal_lymphatic_vessel | 1.58255571 |
30 | MP0000749_muscle_degeneration | 1.56853307 |
31 | MP0004036_abnormal_muscle_relaxation | 1.53825174 |
32 | MP0002933_joint_inflammation | 1.53803951 |
33 | MP0005508_abnormal_skeleton_morphology | 1.53415987 |
34 | MP0004185_abnormal_adipocyte_glucose | 1.52598662 |
35 | MP0005257_abnormal_intraocular_pressure | 1.52200809 |
36 | MP0009780_abnormal_chondrocyte_physiolo | 1.46944831 |
37 | MP0002108_abnormal_muscle_morphology | 1.46455164 |
38 | MP0004233_abnormal_muscle_weight | 1.43820960 |
39 | MP0003172_abnormal_lysosome_physiology | 1.42531029 |
40 | MP0000343_altered_response_to | 1.39829435 |
41 | MP0005666_abnormal_adipose_tissue | 1.39485202 |
42 | MP0003724_increased_susceptibility_to | 1.39205188 |
43 | MP0005330_cardiomyopathy | 1.38663534 |
44 | MP0004130_abnormal_muscle_cell | 1.33353738 |
45 | MP0009053_abnormal_anal_canal | 1.28789724 |
46 | MP0000534_abnormal_ureter_morphology | 1.28471244 |
47 | MP0003385_abnormal_body_wall | 1.27894202 |
48 | MP0000750_abnormal_muscle_regeneration | 1.24037816 |
49 | MP0005375_adipose_tissue_phenotype | 1.23073000 |
50 | MP0005409_darkened_coat_color | 1.22321072 |
51 | MP0006082_CNS_inflammation | 1.22190701 |
52 | MP0005451_abnormal_body_composition | 1.20830878 |
53 | MP0004134_abnormal_chest_morphology | 1.18114690 |
54 | MP0005023_abnormal_wound_healing | 1.18044932 |
55 | MP0002139_abnormal_hepatobiliary_system | 1.17642668 |
56 | MP0001533_abnormal_skeleton_physiology | 1.17294014 |
57 | MP0004087_abnormal_muscle_fiber | 1.16184101 |
58 | * MP0000767_abnormal_smooth_muscle | 1.15037088 |
59 | MP0000762_abnormal_tongue_morphology | 1.14599258 |
60 | MP0000733_abnormal_muscle_development | 1.14149220 |
61 | MP0000003_abnormal_adipose_tissue | 1.13013659 |
62 | MP0003942_abnormal_urinary_system | 1.12770483 |
63 | MP0003091_abnormal_cell_migration | 1.11896690 |
64 | MP0005360_urolithiasis | 1.11648391 |
65 | MP0003634_abnormal_glial_cell | 1.10611543 |
66 | MP0003941_abnormal_skin_development | 1.09815226 |
67 | MP0006138_congestive_heart_failure | 1.08889707 |
68 | MP0005390_skeleton_phenotype | 1.07251429 |
69 | MP0001542_abnormal_bone_strength | 1.07155173 |
70 | MP0000013_abnormal_adipose_tissue | 1.06744584 |
71 | MP0008775_abnormal_heart_ventricle | 1.06375018 |
72 | MP0005164_abnormal_response_to | 1.05635717 |
73 | MP0003828_pulmonary_edema | 1.05619407 |
74 | * MP0002060_abnormal_skin_morphology | 1.04456825 |
75 | MP0008260_abnormal_autophagy | 1.04421375 |
76 | MP0001348_abnormal_lacrimal_gland | 1.04153208 |
77 | MP0003300_gastrointestinal_ulcer | 1.03974222 |
78 | MP0000747_muscle_weakness | 1.03577406 |
79 | MP0002089_abnormal_postnatal_growth/wei | 1.02839504 |
80 | MP0002972_abnormal_cardiac_muscle | 1.02636816 |
81 | MP0003195_calcinosis | 1.01900698 |
82 | MP0001661_extended_life_span | 1.00133549 |
83 | MP0002998_abnormal_bone_remodeling | 0.99718069 |
84 | MP0000604_amyloidosis | 0.99544443 |
85 | MP0003252_abnormal_bile_duct | 0.97847318 |
86 | MP0010352_gastrointestinal_tract_polyps | 0.97701500 |
87 | MP0003136_yellow_coat_color | 0.97168402 |
88 | MP0010630_abnormal_cardiac_muscle | 0.96549550 |
89 | MP0005165_increased_susceptibility_to | 0.96057619 |
90 | MP0000858_altered_metastatic_potential | 0.95722874 |
91 | MP0005595_abnormal_vascular_smooth | 0.93395343 |
92 | MP0001544_abnormal_cardiovascular_syste | 0.91917719 |
93 | MP0005385_cardiovascular_system_phenoty | 0.91917719 |
94 | MP0005076_abnormal_cell_differentiation | 0.91286461 |
95 | MP0003075_altered_response_to | 0.91204112 |
96 | MP0001243_abnormal_dermal_layer | 0.91023914 |
97 | * MP0002128_abnormal_blood_circulation | 0.90162561 |
98 | MP0003806_abnormal_nucleotide_metabolis | 0.90051997 |
99 | MP0003045_fibrosis | 0.89386042 |
100 | MP0002118_abnormal_lipid_homeostasis | 0.88951387 |
101 | MP0001851_eye_inflammation | 0.87451817 |
102 | MP0004215_abnormal_myocardial_fiber | 0.85781717 |
103 | MP0002896_abnormal_bone_mineralization | 0.85762640 |
104 | MP0001299_abnormal_eye_distance/ | 0.85626452 |
105 | * MP0001614_abnormal_blood_vessel | 0.85440179 |
106 | MP0010329_abnormal_lipoprotein_level | 0.84100916 |
107 | MP0000249_abnormal_blood_vessel | 0.83492968 |
108 | MP0005369_muscle_phenotype | 0.80136749 |
109 | MP0002932_abnormal_joint_morphology | 0.79597991 |
110 | MP0000163_abnormal_cartilage_morphology | 0.78961116 |
111 | MP0005620_abnormal_muscle_contractility | 0.78577662 |
112 | MP0001915_intracranial_hemorrhage | 0.78538664 |
113 | MP0000759_abnormal_skeletal_muscle | 0.78493401 |
114 | MP0000678_abnormal_parathyroid_gland | 0.78489787 |
115 | MP0000428_abnormal_craniofacial_morphol | 0.78162517 |
116 | MP0002113_abnormal_skeleton_development | 0.77845099 |
117 | MP0000537_abnormal_urethra_morphology | 0.77539923 |
118 | MP0009250_abnormal_appendicular_skeleto | 0.77446700 |
119 | MP0005167_abnormal_blood-brain_barrier | 0.77373865 |
120 | MP0002115_abnormal_skeleton_extremities | 0.76074371 |
121 | MP0005193_abnormal_anterior_eye | 0.75047343 |
122 | MP0000467_abnormal_esophagus_morphology | 0.74393155 |
123 | MP0002282_abnormal_trachea_morphology | 0.74046362 |
124 | MP0005365_abnormal_bile_salt | 0.73185471 |
125 | MP0003448_altered_tumor_morphology | 0.72191364 |
126 | MP0005197_abnormal_uvea_morphology | 0.72068280 |
127 | MP0003303_peritoneal_inflammation | 0.71483884 |
128 | MP0003329_amyloid_beta_deposits | 0.70480842 |
129 | MP0002106_abnormal_muscle_physiology | 0.70426409 |
130 | MP0005408_hypopigmentation | 0.70269988 |
131 | MP0002925_abnormal_cardiovascular_devel | 0.69817976 |
132 | MP0003115_abnormal_respiratory_system | 0.69574801 |
133 | MP0003453_abnormal_keratinocyte_physiol | 0.65147303 |
134 | MP0000432_abnormal_head_morphology | 0.63294715 |
135 | MP0003755_abnormal_palate_morphology | 0.61321144 |
136 | MP0002697_abnormal_eye_size | 0.60256372 |
137 | MP0002092_abnormal_eye_morphology | 0.60045595 |
138 | MP0001175_abnormal_lung_morphology | 0.59231049 |
139 | MP0000462_abnormal_digestive_system | 0.59201109 |
140 | MP0005621_abnormal_cell_physiology | 0.58984800 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Premature rupture of membranes (HP:0001788) | 5.17950566 |
2 | Protrusio acetabuli (HP:0003179) | 5.09104302 |
3 | Broad metatarsal (HP:0001783) | 4.44563545 |
4 | Systemic lupus erythematosus (HP:0002725) | 3.65496050 |
5 | Ankle contracture (HP:0006466) | 3.51945325 |
6 | Cerebral aneurysm (HP:0004944) | 3.37491554 |
7 | Muscle fiber splitting (HP:0003555) | 3.31721667 |
8 | Shallow orbits (HP:0000586) | 3.28083793 |
9 | Complement deficiency (HP:0004431) | 3.16237027 |
10 | Axonal loss (HP:0003447) | 3.06034808 |
11 | Peritonitis (HP:0002586) | 3.00896224 |
12 | Biconcave vertebral bodies (HP:0004586) | 2.97818827 |
13 | Hypoplastic ischia (HP:0003175) | 2.97197542 |
14 | Follicular hyperkeratosis (HP:0007502) | 2.90308664 |
15 | Cervical subluxation (HP:0003308) | 2.90201494 |
16 | Genu recurvatum (HP:0002816) | 2.86871106 |
17 | Increased cerebral lipofuscin (HP:0011813) | 2.85599983 |
18 | * Aortic dissection (HP:0002647) | 2.77673635 |
19 | Increased connective tissue (HP:0009025) | 2.76490905 |
20 | Hyporeflexia of lower limbs (HP:0002600) | 2.75906527 |
21 | Dilatation of the ascending aorta (HP:0005111) | 2.70452548 |
22 | Type 1 muscle fiber predominance (HP:0003803) | 2.70218742 |
23 | Neurofibrillary tangles (HP:0002185) | 2.70059418 |
24 | Abnormality of the ischium (HP:0003174) | 2.69464680 |
25 | Elbow flexion contracture (HP:0002987) | 2.68780136 |
26 | Nonimmune hydrops fetalis (HP:0001790) | 2.67432625 |
27 | Dysostosis multiplex (HP:0000943) | 2.67319693 |
28 | Glomerulonephritis (HP:0000099) | 2.62991578 |
29 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.60756124 |
30 | Deep venous thrombosis (HP:0002625) | 2.59251848 |
31 | Vertebral compression fractures (HP:0002953) | 2.59102917 |
32 | Asymmetric septal hypertrophy (HP:0001670) | 2.58871289 |
33 | Atrophic scars (HP:0001075) | 2.57084971 |
34 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.54534049 |
35 | * Soft skin (HP:0000977) | 2.54029551 |
36 | Xanthomatosis (HP:0000991) | 2.53569934 |
37 | Achilles tendon contracture (HP:0001771) | 2.52241087 |
38 | Spinal rigidity (HP:0003306) | 2.48802377 |
39 | Abnormality of complement system (HP:0005339) | 2.48120912 |
40 | Upper limb amyotrophy (HP:0009129) | 2.46498976 |
41 | Distal upper limb amyotrophy (HP:0007149) | 2.46498976 |
42 | Abnormality of the Achilles tendon (HP:0005109) | 2.42471057 |
43 | Vascular tortuosity (HP:0004948) | 2.42299516 |
44 | Aortic aneurysm (HP:0004942) | 2.40746405 |
45 | * Blue sclerae (HP:0000592) | 2.40000371 |
46 | Wormian bones (HP:0002645) | 2.39436438 |
47 | Mitral stenosis (HP:0001718) | 2.39066978 |
48 | Arterial tortuosity (HP:0005116) | 2.37548062 |
49 | Hyperlipoproteinemia (HP:0010980) | 2.35972498 |
50 | Osteolytic defects of the hand bones (HP:0009699) | 2.35464105 |
51 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.35464105 |
52 | Mitral regurgitation (HP:0001653) | 2.35236274 |
53 | Increased variability in muscle fiber diameter (HP:0003557) | 2.35227802 |
54 | Myocardial infarction (HP:0001658) | 2.34138421 |
55 | * Abnormal delivery (HP:0001787) | 2.33632912 |
56 | * Joint laxity (HP:0001388) | 2.33197291 |
57 | Mitral valve prolapse (HP:0001634) | 2.31429775 |
58 | Short nail (HP:0001799) | 2.30384972 |
59 | Ovoid vertebral bodies (HP:0003300) | 2.28302662 |
60 | * Hyperextensible skin (HP:0000974) | 2.26703056 |
61 | Hypoplasia of the iris (HP:0007676) | 2.25920005 |
62 | Bowel diverticulosis (HP:0005222) | 2.23330376 |
63 | Neonatal short-limb short stature (HP:0008921) | 2.21689088 |
64 | Fragile skin (HP:0001030) | 2.21511560 |
65 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.20677724 |
66 | Exercise-induced muscle cramps (HP:0003710) | 2.20428855 |
67 | Amyloidosis (HP:0011034) | 2.19895961 |
68 | Abnormality of dentin (HP:0010299) | 2.19657548 |
69 | Epiphyseal dysplasia (HP:0002656) | 2.19148481 |
70 | Vacuolated lymphocytes (HP:0001922) | 2.17917788 |
71 | Coxa vara (HP:0002812) | 2.17773167 |
72 | Mucopolysacchariduria (HP:0008155) | 2.15744534 |
73 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.15744534 |
74 | Renal duplication (HP:0000075) | 2.15234760 |
75 | Skin nodule (HP:0200036) | 2.14668793 |
76 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.14302066 |
77 | Slender build (HP:0001533) | 2.13359717 |
78 | Hand muscle atrophy (HP:0009130) | 2.08750639 |
79 | Natal tooth (HP:0000695) | 2.07298181 |
80 | Abnormality of carpal bone ossification (HP:0006257) | 2.06775437 |
81 | Abnormality of glycolipid metabolism (HP:0010969) | 2.06553553 |
82 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.06553553 |
83 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.06553553 |
84 | Breech presentation (HP:0001623) | 2.05675937 |
85 | Short hallux (HP:0010109) | 2.04651727 |
86 | Protuberant abdomen (HP:0001538) | 2.04233009 |
87 | Ventricular tachycardia (HP:0004756) | 2.03587877 |
88 | Hyperacusis (HP:0010780) | 2.02624044 |
89 | Osteoarthritis (HP:0002758) | 2.02230394 |
90 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.01438900 |
91 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.01438900 |
92 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.01438900 |
93 | Joint stiffness (HP:0001387) | 2.00757867 |
94 | Bell-shaped thorax (HP:0001591) | 2.00273147 |
95 | Coronal craniosynostosis (HP:0004440) | 1.99455265 |
96 | Peripheral demyelination (HP:0011096) | 1.98560684 |
97 | Sudden death (HP:0001699) | 1.98334838 |
98 | Difficulty running (HP:0009046) | 1.97963076 |
99 | Intrahepatic cholestasis (HP:0001406) | 1.97923984 |
100 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.97059150 |
101 | Hypoalphalipoproteinemia (HP:0003233) | 1.96845043 |
102 | Lipoatrophy (HP:0100578) | 1.96009725 |
103 | Onion bulb formation (HP:0003383) | 1.95730967 |
104 | Ectopia lentis (HP:0001083) | 1.94185431 |
105 | Cholecystitis (HP:0001082) | 1.92922762 |
106 | Abnormal gallbladder physiology (HP:0012438) | 1.92922762 |
107 | Cerebral inclusion bodies (HP:0100314) | 1.92753011 |
108 | Wrist flexion contracture (HP:0001239) | 1.92100170 |
109 | Abnormal ossification of hand bones (HP:0005921) | 1.91895727 |
110 | Aortic regurgitation (HP:0001659) | 1.91253511 |
111 | Aneurysm (HP:0002617) | 1.91019142 |
112 | Venous abnormality (HP:0002624) | 1.90807409 |
113 | Protruding ear (HP:0000411) | 1.90411475 |
114 | Cardiovascular calcification (HP:0011915) | 1.89334949 |
115 | Turricephaly (HP:0000262) | 1.88748878 |
116 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.88522061 |
117 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.88522061 |
118 | * Disproportionate tall stature (HP:0001519) | 1.88341767 |
119 | Ulnar bowing (HP:0003031) | 1.88147599 |
120 | Generalized amyotrophy (HP:0003700) | 1.87387043 |
121 | Hypoventilation (HP:0002791) | 1.87223424 |
122 | Infantile muscular hypotonia (HP:0008947) | 1.86436385 |
123 | * Bladder diverticulum (HP:0000015) | 1.86188378 |
124 | Scapular winging (HP:0003691) | 1.85784978 |
125 | Pterygium (HP:0001059) | 1.84766577 |
126 | Round ear (HP:0100830) | 1.84184145 |
127 | Cupped ribs (HP:0000887) | 1.84158499 |
128 | Pulmonary artery stenosis (HP:0004415) | 1.84117969 |
129 | Thin bony cortex (HP:0002753) | 1.83444915 |
130 | Wide anterior fontanel (HP:0000260) | 1.83401745 |
131 | Nuclear cataract (HP:0100018) | 1.82431733 |
132 | Spondylolisthesis (HP:0003302) | 1.81083174 |
133 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.80608379 |
134 | Loss of speech (HP:0002371) | 1.80378942 |
135 | Abnormality of the acetabulum (HP:0003170) | 1.80113342 |
136 | Platyspondyly (HP:0000926) | 1.79676366 |
137 | * Inguinal hernia (HP:0000023) | 1.77774642 |
138 | Back pain (HP:0003418) | 1.76932650 |
139 | Flat acetabular roof (HP:0003180) | 1.76866727 |
140 | Venous insufficiency (HP:0005293) | 1.76823914 |
141 | Osteopenia (HP:0000938) | 1.75692871 |
142 | Trismus (HP:0000211) | 1.75169506 |
143 | Bowing of the arm (HP:0006488) | 1.74568499 |
144 | Bowed forearm bones (HP:0003956) | 1.74568499 |
145 | Camptodactyly of toe (HP:0001836) | 1.73811395 |
146 | Overgrowth (HP:0001548) | 1.72161285 |
147 | Long toe (HP:0010511) | 1.71719556 |
148 | Congenital glaucoma (HP:0001087) | 1.70279186 |
149 | Femoral bowing (HP:0002980) | 1.69903882 |
150 | J-shaped sella turcica (HP:0002680) | 1.67891949 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHB1 | 3.89013006 |
2 | TTN | 3.18598162 |
3 | TGFBR2 | 3.14799245 |
4 | STK39 | 2.78897641 |
5 | KDR | 2.75706743 |
6 | DDR2 | 2.71505397 |
7 | ERN1 | 2.71412117 |
8 | TRIB3 | 2.59509753 |
9 | TIE1 | 2.56339777 |
10 | EPHA2 | 2.53215874 |
11 | TESK1 | 2.32519972 |
12 | MET | 2.31993949 |
13 | IRAK3 | 2.18063287 |
14 | SIK1 | 2.01558645 |
15 | PDGFRA | 1.99439333 |
16 | LATS2 | 1.94151053 |
17 | PKN2 | 1.88026189 |
18 | DMPK | 1.71701256 |
19 | SMG1 | 1.71120058 |
20 | CAMK1D | 1.68446735 |
21 | PKN1 | 1.67907035 |
22 | ICK | 1.65191626 |
23 | PBK | 1.60555721 |
24 | EEF2K | 1.58089789 |
25 | NME2 | 1.56106980 |
26 | CAMK1G | 1.55341103 |
27 | FGFR2 | 1.45390576 |
28 | BCKDK | 1.40873679 |
29 | TRPM7 | 1.34475517 |
30 | BMX | 1.31571181 |
31 | ARAF | 1.29044127 |
32 | PHKG2 | 1.29016783 |
33 | PHKG1 | 1.29016783 |
34 | OXSR1 | 1.27880575 |
35 | PRKD1 | 1.27481421 |
36 | WNK4 | 1.19175375 |
37 | WNK1 | 1.18193124 |
38 | FGFR4 | 1.15366439 |
39 | CDC42BPA | 1.14759428 |
40 | PTK6 | 1.14174134 |
41 | CDK12 | 1.14125658 |
42 | PAK2 | 1.12133186 |
43 | PIM2 | 1.10979978 |
44 | LATS1 | 1.10026942 |
45 | KSR2 | 1.09166875 |
46 | CSK | 1.08123779 |
47 | KIT | 1.05629765 |
48 | TAOK2 | 1.05005547 |
49 | EPHA3 | 1.04835663 |
50 | LMTK2 | 1.04730371 |
51 | ROCK2 | 1.04199469 |
52 | MYLK | 1.00859912 |
53 | INSRR | 0.98611532 |
54 | MAPK15 | 0.98208842 |
55 | STK38 | 0.97596048 |
56 | NEK9 | 0.96827999 |
57 | PDGFRB | 0.94773418 |
58 | TBK1 | 0.94078326 |
59 | JAK1 | 0.93333429 |
60 | RIPK1 | 0.92883952 |
61 | FGR | 0.91744701 |
62 | MAPKAPK5 | 0.90733112 |
63 | OBSCN | 0.89765615 |
64 | PAK4 | 0.88692094 |
65 | EPHB2 | 0.87390541 |
66 | PTK2B | 0.85846974 |
67 | PAK3 | 0.84652427 |
68 | CLK1 | 0.82212433 |
69 | GSK3A | 0.82068424 |
70 | MAP3K3 | 0.81136808 |
71 | MAP3K6 | 0.79826721 |
72 | MAPKAPK3 | 0.77646432 |
73 | RPS6KA2 | 0.77406945 |
74 | MAP3K8 | 0.76886742 |
75 | MST1R | 0.75060918 |
76 | CSF1R | 0.74685102 |
77 | PRPF4B | 0.74292255 |
78 | CDK8 | 0.74049136 |
79 | ILK | 0.73240432 |
80 | ROCK1 | 0.73004492 |
81 | TYK2 | 0.72260875 |
82 | DAPK3 | 0.69998713 |
83 | MAP2K3 | 0.69770211 |
84 | PIK3CA | 0.69546141 |
85 | TESK2 | 0.69145515 |
86 | PRKAA2 | 0.68818708 |
87 | PTK2 | 0.67239515 |
88 | PRKCH | 0.66897988 |
89 | PRKD2 | 0.66287902 |
90 | MAPK12 | 0.65618111 |
91 | CAMK2D | 0.65170502 |
92 | NTRK1 | 0.64510059 |
93 | LIMK1 | 0.63099661 |
94 | PRKD3 | 0.62347725 |
95 | FER | 0.61322723 |
96 | MAPK7 | 0.59557596 |
97 | STK3 | 0.59451063 |
98 | MTOR | 0.58258936 |
99 | ERBB4 | 0.58118209 |
100 | PDPK1 | 0.56383658 |
101 | PDK2 | 0.56148110 |
102 | MAP3K2 | 0.54568103 |
103 | FLT3 | 0.54264347 |
104 | RET | 0.51920013 |
105 | CDK7 | 0.50955892 |
106 | BLK | 0.50944881 |
107 | PRKCE | 0.50518202 |
108 | MAPK11 | 0.50508090 |
109 | INSR | 0.48912623 |
110 | TYRO3 | 0.48321186 |
111 | PAK1 | 0.48058653 |
112 | MOS | 0.46228634 |
113 | BRAF | 0.44752731 |
114 | IGF1R | 0.44738481 |
115 | BRSK1 | 0.43962878 |
116 | SCYL2 | 0.43809392 |
117 | FGFR3 | 0.42441571 |
118 | ABL1 | 0.42289475 |
119 | PIK3CG | 0.42252428 |
120 | ABL2 | 0.42135524 |
121 | LRRK2 | 0.41958922 |
122 | SRC | 0.41914851 |
123 | FGFR1 | 0.41347613 |
124 | EIF2AK1 | 0.40809773 |
125 | STK10 | 0.39423820 |
126 | HCK | 0.39297768 |
127 | NEK2 | 0.37949021 |
128 | JAK2 | 0.37026194 |
129 | MAP3K13 | 0.37002121 |
130 | CDK15 | 0.36657056 |
131 | PAK6 | 0.36563267 |
132 | PRKG2 | 0.36001369 |
133 | GRK7 | 0.35913819 |
134 | MAP2K2 | 0.35665038 |
135 | MAP2K1 | 0.35323233 |
136 | CDK11A | 0.35241603 |
137 | MAP3K1 | 0.34488344 |
138 | MELK | 0.33128824 |
139 | CDK18 | 0.31963103 |
140 | MAPKAPK2 | 0.31360019 |
141 | AKT2 | 0.30590592 |
142 | NEK1 | 0.30170027 |
143 | CDK9 | 0.29108349 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.84505993 |
2 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.67597775 |
3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.53149185 |
4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.45031048 |
5 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.40656590 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.32459667 |
7 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.23987070 |
8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.15657730 |
9 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.15188140 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.13334269 |
11 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.09774908 |
12 | Lysosome_Homo sapiens_hsa04142 | 2.05481214 |
13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.03812383 |
14 | Galactose metabolism_Homo sapiens_hsa00052 | 2.01939429 |
15 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.97275191 |
16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.96361799 |
17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.94354427 |
18 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.90234065 |
19 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.87801221 |
20 | Other glycan degradation_Homo sapiens_hsa00511 | 1.85789677 |
21 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.82824482 |
22 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.75699011 |
23 | Malaria_Homo sapiens_hsa05144 | 1.70467835 |
24 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.61574634 |
25 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.61473838 |
26 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.61471044 |
27 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.53155445 |
28 | Focal adhesion_Homo sapiens_hsa04510 | 1.50097180 |
29 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.47625772 |
30 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.40040174 |
31 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.39024763 |
32 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.32293758 |
33 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.30129662 |
34 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.29701324 |
35 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.29123354 |
36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.27620858 |
37 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.22409838 |
38 | Histidine metabolism_Homo sapiens_hsa00340 | 1.22029267 |
39 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.20037591 |
40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.19737843 |
41 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.19002935 |
42 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.18618430 |
43 | Peroxisome_Homo sapiens_hsa04146 | 1.16803401 |
44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.13953884 |
45 | Amoebiasis_Homo sapiens_hsa05146 | 1.11720862 |
46 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.06339728 |
47 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.05968565 |
48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.04335448 |
49 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.03995575 |
50 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.96817407 |
51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.95448166 |
52 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.94164464 |
53 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.93770149 |
54 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.93325654 |
55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.92890185 |
56 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.92378351 |
57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.91448987 |
58 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.88328542 |
59 | Thyroid cancer_Homo sapiens_hsa05216 | 0.87973799 |
60 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.87559734 |
61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85921855 |
62 | Phagosome_Homo sapiens_hsa04145 | 0.85901999 |
63 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.84673962 |
64 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.84105326 |
65 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.83980788 |
66 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.82051470 |
67 | Carbon metabolism_Homo sapiens_hsa01200 | 0.81395986 |
68 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.81043363 |
69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.80678867 |
70 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.79762756 |
71 | Prion diseases_Homo sapiens_hsa05020 | 0.78791661 |
72 | Glioma_Homo sapiens_hsa05214 | 0.77997307 |
73 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.76053877 |
74 | Pathways in cancer_Homo sapiens_hsa05200 | 0.75963349 |
75 | ABC transporters_Homo sapiens_hsa02010 | 0.75877793 |
76 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.75190506 |
77 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.75113953 |
78 | Bile secretion_Homo sapiens_hsa04976 | 0.74603033 |
79 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.74231019 |
80 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.73812636 |
81 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.72446897 |
82 | Melanoma_Homo sapiens_hsa05218 | 0.72398238 |
83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71826373 |
84 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71645551 |
85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.70586003 |
86 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.69991468 |
87 | Shigellosis_Homo sapiens_hsa05131 | 0.68252474 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.67390258 |
89 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.67013012 |
90 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.66283696 |
91 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.65930329 |
92 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.65184170 |
93 | * Lysine degradation_Homo sapiens_hsa00310 | 0.64759298 |
94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64399575 |
95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.63830440 |
96 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.62781227 |
97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.62693117 |
98 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.60651679 |
99 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.60595072 |
100 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.60346050 |
101 | Pertussis_Homo sapiens_hsa05133 | 0.57860693 |
102 | Melanogenesis_Homo sapiens_hsa04916 | 0.57331675 |
103 | Prostate cancer_Homo sapiens_hsa05215 | 0.57123169 |
104 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.56900153 |
105 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.56559574 |
106 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.56270084 |
107 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55065075 |
108 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.54159185 |
109 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53657263 |
110 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.53282259 |
111 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.53152162 |
112 | Endometrial cancer_Homo sapiens_hsa05213 | 0.53070845 |
113 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.52872114 |
114 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.52782353 |
115 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.52285103 |
116 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.51583237 |
117 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.51505743 |
118 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.51264757 |
119 | Viral myocarditis_Homo sapiens_hsa05416 | 0.51106623 |
120 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.51028533 |
121 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.50741742 |
122 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.50373868 |
123 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47200891 |
124 | Adherens junction_Homo sapiens_hsa04520 | 0.47140640 |
125 | Insulin resistance_Homo sapiens_hsa04931 | 0.47123437 |
126 | Axon guidance_Homo sapiens_hsa04360 | 0.46815335 |
127 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.46308455 |
128 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45647579 |
129 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.45615292 |
130 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.45592681 |
131 | Salmonella infection_Homo sapiens_hsa05132 | 0.45289781 |
132 | Gap junction_Homo sapiens_hsa04540 | 0.44470636 |
133 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.43558709 |
134 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.41748311 |
135 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.41401138 |
136 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.40843377 |
137 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.40687628 |
138 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.40597156 |
139 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.40266714 |
140 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.40220737 |
141 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.40042520 |
142 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.39999159 |
143 | Tight junction_Homo sapiens_hsa04530 | 0.38439309 |
144 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.38322944 |
145 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.37893353 |
146 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.37561080 |
147 | Endocytosis_Homo sapiens_hsa04144 | 0.37524967 |
148 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.36862146 |
149 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35103808 |
150 | Bladder cancer_Homo sapiens_hsa05219 | 0.34530817 |