PLSCR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of interleukin-12 production (GO:0032695)4.44266235
2macrophage activation involved in immune response (GO:0002281)4.40095206
3detection of molecule of bacterial origin (GO:0032490)4.35129396
4interferon-gamma-mediated signaling pathway (GO:0060333)4.18154427
5hepatocyte apoptotic process (GO:0097284)4.15955725
6response to peptidoglycan (GO:0032494)3.90978108
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.80859362
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.80859362
9regulation of interferon-beta biosynthetic process (GO:0045357)3.69129878
10positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.67335627
11regulation of dendritic cell antigen processing and presentation (GO:0002604)3.59792433
12cellular response to interferon-alpha (GO:0035457)3.57191779
13positive regulation of toll-like receptor signaling pathway (GO:0034123)3.55864338
14antigen processing and presentation of endogenous antigen (GO:0019883)3.50956480
15cellular response to interferon-gamma (GO:0071346)3.41123529
16detection of biotic stimulus (GO:0009595)3.39913001
17response to interferon-gamma (GO:0034341)3.36869941
18response to host immune response (GO:0052572)3.33591983
19response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.33591983
20* response to interferon-beta (GO:0035456)3.31419159
21response to nitrosative stress (GO:0051409)3.28000932
22myeloid cell activation involved in immune response (GO:0002275)3.26121407
23microglial cell activation (GO:0001774)3.23382187
24negative regulation of cell killing (GO:0031342)3.22242918
25negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.22242918
26regulation of vitamin D biosynthetic process (GO:0060556)3.19134943
27regulation of antigen processing and presentation (GO:0002577)3.18966389
28positive regulation of antigen processing and presentation (GO:0002579)3.16130949
29macrophage activation (GO:0042116)3.13670453
30* defense response to virus (GO:0051607)3.12209576
31neutrophil activation involved in immune response (GO:0002283)3.10206797
32response to host (GO:0075136)3.07845731
33response to host defenses (GO:0052200)3.07845731
34response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.07845731
35regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.07332780
36* regulation of viral genome replication (GO:0045069)3.05210988
37regulation of RIG-I signaling pathway (GO:0039535)3.04789790
38regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.03795682
39positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.01566362
40negative regulation of cytokine production involved in immune response (GO:0002719)2.99822107
41detection of other organism (GO:0098543)2.98748134
42cellular response to interferon-beta (GO:0035458)2.98088030
43negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.97851915
44positive regulation of cellular amide metabolic process (GO:0034250)2.94898909
45lymphocyte chemotaxis (GO:0048247)2.94501208
46positive regulation of interferon-alpha production (GO:0032727)2.93951568
47regulation of type 2 immune response (GO:0002828)2.90721713
48NIK/NF-kappaB signaling (GO:0038061)2.90655629
49ribosomal small subunit assembly (GO:0000028)2.87407345
50regulation of T cell tolerance induction (GO:0002664)2.87124955
51positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.87108807
52cellular extravasation (GO:0045123)2.87042316
53regulation of tolerance induction (GO:0002643)2.85892613
54regulation of interferon-beta production (GO:0032648)2.84975040
55xenobiotic catabolic process (GO:0042178)2.84614938
56regulation of interleukin-12 biosynthetic process (GO:0045075)2.83708989
57positive regulation of T-helper cell differentiation (GO:0045624)2.82522028
58regulation of immunoglobulin secretion (GO:0051023)2.80893825
59regulation of interleukin-8 biosynthetic process (GO:0045414)2.80779480
60regulation of vitamin metabolic process (GO:0030656)2.80205011
61regulation of T-helper 1 cell differentiation (GO:0045625)2.78420663
62antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.77799082
63positive regulation of chemokine biosynthetic process (GO:0045080)2.76721270
64regulation of type I interferon-mediated signaling pathway (GO:0060338)2.76715243
65regulation of interferon-alpha production (GO:0032647)2.76493575
66production of molecular mediator involved in inflammatory response (GO:0002532)2.76441940
67* negative regulation of viral process (GO:0048525)2.76292125
68regulation of cytokine secretion involved in immune response (GO:0002739)2.75354259
69regulation of activation of Janus kinase activity (GO:0010533)2.74979144
70positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.74672169
71regulation of interleukin-12 production (GO:0032655)2.74500203
72regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.73539698
73response to type I interferon (GO:0034340)2.73252113
74response to protozoan (GO:0001562)2.71726620
75positive regulation of interleukin-6 production (GO:0032755)2.70969192
76cellular response to type I interferon (GO:0071357)2.70762904
77type I interferon signaling pathway (GO:0060337)2.70762904
78positive regulation of acute inflammatory response (GO:0002675)2.70469176
79T cell migration (GO:0072678)2.70286689
80germinal center formation (GO:0002467)2.70061086
81positive regulation of chemokine production (GO:0032722)2.69441926
82thrombin receptor signaling pathway (GO:0070493)2.68986952
83modulation of growth of symbiont involved in interaction with host (GO:0044144)2.68982001
84regulation of growth of symbiont in host (GO:0044126)2.68982001
85negative regulation of growth of symbiont in host (GO:0044130)2.68982001
86negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.68982001
87antigen processing and presentation via MHC class Ib (GO:0002475)2.68737246
88regulation of inflammatory response to antigenic stimulus (GO:0002861)2.67346553
89production of molecular mediator of immune response (GO:0002440)2.65369407
90detection of bacterium (GO:0016045)2.64748113
91regulation of chemokine biosynthetic process (GO:0045073)2.63557480
92positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.59369646
93regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)2.58562466
94positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)2.58562466
95CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.58439365
96positive regulation of protein import into nucleus, translocation (GO:0033160)2.56039106
97regulation of podosome assembly (GO:0071801)2.53343099
98positive regulation of T cell mediated cytotoxicity (GO:0001916)2.53305933
99natural killer cell mediated immunity (GO:0002228)2.51966843
100natural killer cell mediated cytotoxicity (GO:0042267)2.51966843
101positive regulation of gamma-delta T cell activation (GO:0046645)2.51669775
102response to interferon-alpha (GO:0035455)2.50500774
103negative regulation of lipid storage (GO:0010888)2.50172817
104regulation of natural killer cell differentiation (GO:0032823)2.49256785
105positive regulation of natural killer cell differentiation (GO:0032825)2.49010291
106positive regulation of interleukin-12 production (GO:0032735)2.48798346
107* negative regulation of viral genome replication (GO:0045071)2.48530156
108positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.48376858
109regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.46622948
110myeloid dendritic cell differentiation (GO:0043011)2.46505379
111regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.45150325
112natural killer cell activation involved in immune response (GO:0002323)2.45028426
113Arp2/3 complex-mediated actin nucleation (GO:0034314)2.44520264
114defense response to protozoan (GO:0042832)2.43596106
115cellular response to exogenous dsRNA (GO:0071360)2.42449387
116regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510)2.41402088
117positive regulation of humoral immune response (GO:0002922)2.40512608
118immunoglobulin mediated immune response (GO:0016064)2.39789837
119interferon-gamma secretion (GO:0072643)2.39195270
120regulation of T-helper cell differentiation (GO:0045622)2.37927888
121positive regulation of interferon-beta production (GO:0032728)2.37225070
122positive regulation of interleukin-17 production (GO:0032740)2.35983537
123myeloid dendritic cell activation (GO:0001773)2.35614543
124positive regulation of alpha-beta T cell proliferation (GO:0046641)2.30335382
125regulation of alpha-beta T cell proliferation (GO:0046640)2.27509203
126response to muramyl dipeptide (GO:0032495)2.26812697
127leukocyte apoptotic process (GO:0071887)2.26734436
128positive regulation of type 2 immune response (GO:0002830)2.26268439
129folic acid-containing compound biosynthetic process (GO:0009396)2.25958084
130positive regulation of B cell mediated immunity (GO:0002714)2.24558371
131positive regulation of immunoglobulin mediated immune response (GO:0002891)2.24558371
132hydrogen peroxide biosynthetic process (GO:0050665)2.23797406
133positive regulation of defense response to virus by host (GO:0002230)2.23261045
134granulocyte activation (GO:0036230)2.22653719
135positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.22532034
136positive regulation of NF-kappaB import into nucleus (GO:0042346)2.22531565
137T cell apoptotic process (GO:0070231)2.21296978
138neutrophil activation (GO:0042119)2.20937116
139B cell mediated immunity (GO:0019724)2.20822651
140lipopolysaccharide-mediated signaling pathway (GO:0031663)2.17918160
141regulation of memory T cell differentiation (GO:0043380)2.17634646
142positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.16746880
143cell adhesion mediated by integrin (GO:0033627)2.16670291
144modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.16226121
145positive regulation by organism of defense response of other organism involved in symbiotic interact2.16226121
146modulation by symbiont of host immune response (GO:0052553)2.16226121
147positive regulation by symbiont of host defense response (GO:0052509)2.16226121
148modulation by symbiont of host defense response (GO:0052031)2.16226121
149modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.16226121
150T-helper 1 type immune response (GO:0042088)2.15552842
151detection of external biotic stimulus (GO:0098581)2.14924214
152regulation of heterotypic cell-cell adhesion (GO:0034114)2.14769077
153monocyte chemotaxis (GO:0002548)2.14537817
154regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.14156800
155pentose-phosphate shunt (GO:0006098)2.14076682
156positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.13053073
157positive regulation of transcription factor import into nucleus (GO:0042993)2.13016088
158positive regulation of tumor necrosis factor production (GO:0032760)2.12593063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.88174630
2E2F7_22180533_ChIP-Seq_HELA_Human3.80795490
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.71661811
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.52867761
5SMAD_19615063_ChIP-ChIP_OVARY_Human3.08693356
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.64780842
7RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.63513265
8IRF8_21731497_ChIP-ChIP_J774_Mouse2.56172213
9* EGR1_19374776_ChIP-ChIP_THP-1_Human2.55643965
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.55093056
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.53258374
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.39253495
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.31960982
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.24523642
15* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.20244191
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.18777376
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.15678691
18* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.14156266
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.02388183
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.96202806
21STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.91857147
22* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.90923877
23MYC_18555785_ChIP-Seq_MESCs_Mouse1.89416307
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88834895
25* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.77938912
26SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.77171964
27* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.76065544
28IRF8_27001747_Chip-Seq_BMDM_Mouse1.70698360
29VDR_24787735_ChIP-Seq_THP-1_Human1.67863089
30PPARA_22158963_ChIP-Seq_LIVER_Mouse1.65697367
31SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.65551780
32EGR1_23403033_ChIP-Seq_LIVER_Mouse1.64922621
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.63548338
34PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.63301060
35RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62046941
36CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.58253745
37SPI1_23127762_ChIP-Seq_K562_Human1.56121493
38RUNX_20019798_ChIP-Seq_JUKART_Human1.55140518
39TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.54270760
40PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.54266212
41* RXR_22158963_ChIP-Seq_LIVER_Mouse1.52138130
42GATA3_26560356_Chip-Seq_TH2_Human1.51123965
43* SPI1_23547873_ChIP-Seq_NB4_Human1.49766333
44NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.44964627
45MYB_26560356_Chip-Seq_TH2_Human1.44707869
46* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.44150291
47* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.42196888
48* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41701422
49SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.39860860
50SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.39860860
51GATA1_22025678_ChIP-Seq_K562_Human1.38053530
52CLOCK_20551151_ChIP-Seq_293T_Human1.37384766
53AR_21909140_ChIP-Seq_LNCAP_Human1.36726609
54BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35216687
55* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34624658
56PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.33098814
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32537232
58Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.31862297
59RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.30680025
60FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.29870012
61SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.28286375
62MYB_26560356_Chip-Seq_TH1_Human1.27284051
63GATA3_27048872_Chip-Seq_THYMUS_Human1.26096875
64ESR1_21235772_ChIP-Seq_MCF-7_Human1.25672958
65* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25576048
66MAF_26560356_Chip-Seq_TH1_Human1.24628205
67RUNX1_22412390_ChIP-Seq_EML_Mouse1.24544136
68FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.24216883
69* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.24116481
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.22306253
71HIF1A_21447827_ChIP-Seq_MCF-7_Human1.21082350
72SCL_19346495_ChIP-Seq_HPC-7_Human1.21080635
73HOXB4_20404135_ChIP-ChIP_EML_Mouse1.20264493
74NELFA_20434984_ChIP-Seq_ESCs_Mouse1.19783220
75TRIM28_21343339_ChIP-Seq_HEK293_Human1.19010529
76GATA2_21666600_ChIP-Seq_HMVEC_Human1.18439407
77GATA4_25053715_ChIP-Seq_YYC3_Human1.18400230
78* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.18051076
79ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.15662230
80FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.13436372
81LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.12197234
82ELK1_19687146_ChIP-ChIP_HELA_Human1.11596582
83LXR_22158963_ChIP-Seq_LIVER_Mouse1.11257272
84MYC_22102868_ChIP-Seq_BL_Human1.11109026
85KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10157660
86CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10044047
87* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.09605753
88CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09138439
89NOTCH1_21737748_ChIP-Seq_TLL_Human1.09051389
90VDR_24763502_ChIP-Seq_THP-1_Human1.07778004
91E2F1_18555785_ChIP-Seq_MESCs_Mouse1.07718783
92GATA6_25053715_ChIP-Seq_YYC3_Human1.07385599
93GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07140155
94* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.06125158
95GABP_17652178_ChIP-ChIP_JURKAT_Human1.05834542
96VDR_21846776_ChIP-Seq_THP-1_Human1.05605586
97* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05058920
98MYC_19030024_ChIP-ChIP_MESCs_Mouse1.04303702
99CDX2_20551321_ChIP-Seq_CACO-2_Human1.04055207
100MYC_18358816_ChIP-ChIP_MESCs_Mouse1.02657179
101* SOX2_20726797_ChIP-Seq_SW620_Human1.02281853
102E2F4_17652178_ChIP-ChIP_JURKAT_Human1.01724510
103ELK3_25401928_ChIP-Seq_HUVEC_Human1.00767861
104CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99051750
105* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98694714
106SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98480626
107ATF3_27146783_Chip-Seq_COLON_Human0.96063678
108PU_27001747_Chip-Seq_BMDM_Mouse0.95988990
109CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95862331
110CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95443076
111UTX_26944678_Chip-Seq_JUKART_Human0.95175197
112TFEB_21752829_ChIP-Seq_HELA_Human0.93120633
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.91627232
114* SALL4_18804426_ChIP-ChIP_XEN_Mouse0.91311693
115MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.91044192
116POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.89426767
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88521935
118TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.88491957
119PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88418742
120E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.87284702
121ELK1_22589737_ChIP-Seq_MCF10A_Human0.87065515
122TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87037882
123FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.82222703
124FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.81753686
125NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.80099027
126PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79984673
127* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.79638583
128EGR1_19032775_ChIP-ChIP_M12_Human0.79581626
129* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78865867
130PPAR_26484153_Chip-Seq_NCI-H1993_Human0.78586601
131STAT1_20625510_ChIP-Seq_HELA_Human0.78194802
132* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.77405234
133GATA1_19941826_ChIP-Seq_K562_Human0.71071476
134ELF5_23300383_ChIP-Seq_T47D_Human0.69930327
135STAT6_21828071_ChIP-Seq_BEAS2B_Human0.69705361

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009785_altered_susceptibility_to3.18169019
2MP0003724_increased_susceptibility_to2.78595377
3MP0001835_abnormal_antigen_presentation2.66558936
4MP0003436_decreased_susceptibility_to2.50034044
5MP0006082_CNS_inflammation2.27021791
6MP0003300_gastrointestinal_ulcer2.24077794
7MP0002148_abnormal_hypersensitivity_rea2.14957542
8MP0008004_abnormal_stomach_pH2.14264247
9MP0010155_abnormal_intestine_physiology2.12425872
10MP0000685_abnormal_immune_system2.12306875
11MP0005025_abnormal_response_to2.05288946
12MP0010352_gastrointestinal_tract_polyps2.03200940
13MP0002877_abnormal_melanocyte_morpholog2.02426973
14MP0002138_abnormal_hepatobiliary_system2.00534246
15MP0003186_abnormal_redox_activity1.95003293
16MP0001853_heart_inflammation1.90612511
17MP0005000_abnormal_immune_tolerance1.88949608
18MP0005397_hematopoietic_system_phenotyp1.83267383
19MP0001545_abnormal_hematopoietic_system1.83267383
20MP0002419_abnormal_innate_immunity1.81609638
21MP0005387_immune_system_phenotype1.79196176
22MP0001790_abnormal_immune_system1.79196176
23MP0003195_calcinosis1.78941512
24MP0005671_abnormal_response_to1.76287789
25MP0006054_spinal_hemorrhage1.69794570
26MP0002006_tumorigenesis1.69179809
27MP0004947_skin_inflammation1.67981766
28MP0003075_altered_response_to1.65736892
29MP0000490_abnormal_crypts_of1.65457990
30MP0009278_abnormal_bone_marrow1.61731705
31MP0001800_abnormal_humoral_immune1.60185956
32MP0002452_abnormal_antigen_presenting1.60183535
33MP0002723_abnormal_immune_serum1.58403824
34MP0005464_abnormal_platelet_physiology1.58220230
35MP0001845_abnormal_inflammatory_respons1.56357624
36MP0003806_abnormal_nucleotide_metabolis1.56262036
37MP0009764_decreased_sensitivity_to1.56183003
38MP0002405_respiratory_system_inflammati1.55325393
39MP0000858_altered_metastatic_potential1.54465762
40MP0005058_abnormal_lysosome_morphology1.50697047
41MP0004808_abnormal_hematopoietic_stem1.48836923
42MP0003191_abnormal_cellular_cholesterol1.48647657
43MP0001873_stomach_inflammation1.46436238
44MP0002166_altered_tumor_susceptibility1.43856347
45MP0002132_abnormal_respiratory_system1.43822531
46MP0003566_abnormal_cell_adhesion1.43699244
47MP0004264_abnormal_extraembryonic_tissu1.42122618
48MP0003866_abnormal_defecation1.41861142
49MP0001819_abnormal_immune_cell1.41711465
50MP0002420_abnormal_adaptive_immunity1.39830549
51MP0009333_abnormal_splenocyte_physiolog1.39002075
52MP0008469_abnormal_protein_level1.38037777
53MP0004510_myositis1.37697028
54MP0010234_abnormal_vibrissa_follicle1.35787334
55MP0003453_abnormal_keratinocyte_physiol1.30227045
56MP0008875_abnormal_xenobiotic_pharmacok1.28817862
57MP0001533_abnormal_skeleton_physiology1.27176084
58MP0000343_altered_response_to1.24916499
59MP0002139_abnormal_hepatobiliary_system1.21998479
60MP0005023_abnormal_wound_healing1.20851516
61MP0000465_gastrointestinal_hemorrhage1.20259631
62MP0002998_abnormal_bone_remodeling1.16634847
63MP0003763_abnormal_thymus_physiology1.15836553
64MP0003693_abnormal_embryo_hatching1.15766967
65* MP0002398_abnormal_bone_marrow1.15239626
66MP0008260_abnormal_autophagy1.12460727
67MP0005085_abnormal_gallbladder_physiolo1.10314296
68MP0002396_abnormal_hematopoietic_system1.10155822
69MP0003303_peritoneal_inflammation1.09761201
70MP0005360_urolithiasis1.09022020
71* MP0000716_abnormal_immune_system1.08993553
72MP0003828_pulmonary_edema1.05737734
73MP0000689_abnormal_spleen_morphology1.04181484
74MP0009840_abnormal_foam_cell1.03872919
75MP0002254_reproductive_system_inflammat1.03024448
76MP0001881_abnormal_mammary_gland1.01926600
77* MP0002429_abnormal_blood_cell1.01484882
78MP0009643_abnormal_urine_homeostasis1.01384591
79MP0003448_altered_tumor_morphology1.00907223
80MP0002722_abnormal_immune_system0.99513328
81MP0009763_increased_sensitivity_to0.98170915
82MP0005408_hypopigmentation0.97166624
83MP0005365_abnormal_bile_salt0.96383197
84MP0004782_abnormal_surfactant_physiolog0.95999254
85MP0005390_skeleton_phenotype0.95741814
86MP0003172_abnormal_lysosome_physiology0.94966234
87MP0004883_abnormal_blood_vessel0.93681607
88MP0002332_abnormal_exercise_endurance0.92314227
89MP0000477_abnormal_intestine_morphology0.92313506
90MP0005166_decreased_susceptibility_to0.92096569
91MP0005310_abnormal_salivary_gland0.90429081
92MP0002277_abnormal_respiratory_mucosa0.90352837
93MP0003252_abnormal_bile_duct0.89125661
94MP0010307_abnormal_tumor_latency0.87614958
95MP0002136_abnormal_kidney_physiology0.87509788
96MP0000609_abnormal_liver_physiology0.87148503
97MP0003950_abnormal_plasma_membrane0.85819747
98MP0005165_increased_susceptibility_to0.84873768
99MP0003943_abnormal_hepatobiliary_system0.84266499
100MP0002019_abnormal_tumor_incidence0.83541868
101MP0005164_abnormal_response_to0.83474173
102MP0000604_amyloidosis0.82109488
103MP0009765_abnormal_xenobiotic_induced0.81630550
104MP0005076_abnormal_cell_differentiation0.81589196
105MP0003656_abnormal_erythrocyte_physiolo0.81583345
106MP0001666_abnormal_nutrient_absorption0.81095116
107MP0004957_abnormal_blastocyst_morpholog0.80985811
108MP0000627_abnormal_mammary_gland0.78026512
109MP0010368_abnormal_lymphatic_system0.77983199
110MP0004019_abnormal_vitamin_homeostasis0.77882905
111MP0003690_abnormal_glial_cell0.77769479
112MP0001851_eye_inflammation0.77762416
113MP0005319_abnormal_enzyme/_coenzyme0.76460780
114MP0008007_abnormal_cellular_replicative0.76117641
115MP0000598_abnormal_liver_morphology0.75297841
116MP0005451_abnormal_body_composition0.74650821
117MP0005167_abnormal_blood-brain_barrier0.74274981
118MP0001663_abnormal_digestive_system0.73276608
119MP0000249_abnormal_blood_vessel0.73161327
120MP0001542_abnormal_bone_strength0.72722586
121MP0002933_joint_inflammation0.70503821
122MP0003795_abnormal_bone_structure0.68846186
123MP0003091_abnormal_cell_migration0.63260525
124MP0000703_abnormal_thymus_morphology0.60494708
125MP0003045_fibrosis0.59255088
126MP0003183_abnormal_peptide_metabolism0.59028473

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)4.06074783
2Eczematoid dermatitis (HP:0000976)3.90209568
3Myositis (HP:0100614)3.79016424
4Orchitis (HP:0100796)3.72127293
5Interstitial pulmonary disease (HP:0006530)3.70562879
6Abnormality of glycolipid metabolism (HP:0010969)3.65124136
7Abnormality of liposaccharide metabolism (HP:0010968)3.65124136
8Abnormality of glycosphingolipid metabolism (HP:0004343)3.65124136
9Recurrent abscess formation (HP:0002722)3.49326240
10Optic neuritis (HP:0100653)3.42453427
11Retrobulbar optic neuritis (HP:0100654)3.42453427
12Pustule (HP:0200039)3.38630329
13Micronodular cirrhosis (HP:0001413)3.38377064
14Esophageal varix (HP:0002040)3.33890737
15Petechiae (HP:0000967)3.29278625
16Elevated erythrocyte sedimentation rate (HP:0003565)3.25247737
17Thrombocytosis (HP:0001894)3.20712109
18Recurrent cutaneous fungal infections (HP:0011370)3.18362071
19Chronic mucocutaneous candidiasis (HP:0002728)3.18362071
20Mediastinal lymphadenopathy (HP:0100721)3.16633166
21Loss of speech (HP:0002371)3.00852049
22Recurrent bacterial skin infections (HP:0005406)3.00151823
23Meningitis (HP:0001287)2.93940794
24Abnormality of T cell number (HP:0011839)2.92570176
25Recurrent gram-negative bacterial infections (HP:0005420)2.87833991
26Gangrene (HP:0100758)2.83700697
27T lymphocytopenia (HP:0005403)2.78083870
28Gastrointestinal infarctions (HP:0005244)2.76168081
29Recurrent fungal infections (HP:0002841)2.74269123
30Chronic obstructive pulmonary disease (HP:0006510)2.71527305
31Obstructive lung disease (HP:0006536)2.71527305
32Hematochezia (HP:0002573)2.67943099
33Autoimmune thrombocytopenia (HP:0001973)2.67701585
34Amyloidosis (HP:0011034)2.57676965
35Abnormality of macrophages (HP:0004311)2.56336580
36Abnormality of T cell physiology (HP:0011840)2.51298330
37Gingival bleeding (HP:0000225)2.49415030
38Glomerulonephritis (HP:0000099)2.47700795
39IgA deficiency (HP:0002720)2.46340070
40Increased serum ferritin (HP:0003281)2.43677296
41IgM deficiency (HP:0002850)2.43254768
42Abnormality of monocarboxylic acid metabolism (HP:0010996)2.42639820
43Hypergammaglobulinemia (HP:0010702)2.42048934
44Anorexia (HP:0002039)2.40647609
45Vasculitis (HP:0002633)2.40588685
46Periodontitis (HP:0000704)2.40141006
47Joint swelling (HP:0001386)2.38914297
48Leukocytosis (HP:0001974)2.36816334
49Basal ganglia calcification (HP:0002135)2.34411003
50Abnormality of B cell number (HP:0010975)2.33682704
51Abnormal platelet volume (HP:0011876)2.32289437
52Pulmonary embolism (HP:0002204)2.32272517
53Prolonged bleeding time (HP:0003010)2.31323556
54Increased cerebral lipofuscin (HP:0011813)2.30485478
55Polyneuropathy (HP:0001271)2.30444516
56Episodic fever (HP:0001954)2.29937124
57Hepatosplenomegaly (HP:0001433)2.28779871
58Abnormality of transition element cation homeostasis (HP:0011030)2.27103888
59Abnormality of iron homeostasis (HP:0011031)2.27036861
60Arterial thrombosis (HP:0004420)2.26246496
61Increased mean platelet volume (HP:0011877)2.25501302
62Keratoconjunctivitis sicca (HP:0001097)2.24918189
63Vacuolated lymphocytes (HP:0001922)2.23436873
64Abnormality of the nasal mucosa (HP:0000433)2.23341422
65Progressive neurologic deterioration (HP:0002344)2.22995302
66Abnormal number of erythroid precursors (HP:0012131)2.22981578
67Recurrent viral infections (HP:0004429)2.22508227
68Abnormality of cells of the erythroid lineage (HP:0012130)2.21595928
69Eosinophilia (HP:0001880)2.21064596
70Disinhibition (HP:0000734)2.21005002
71Epistaxis (HP:0000421)2.20000216
72Dysostosis multiplex (HP:0000943)2.19493892
73Tetraparesis (HP:0002273)2.17827593
74Nasal polyposis (HP:0100582)2.16240390
75Keratoconjunctivitis (HP:0001096)2.16113210
76Parakeratosis (HP:0001036)2.13650698
77Premature loss of primary teeth (HP:0006323)2.12026344
78Onycholysis (HP:0001806)2.11993710
79Osteolytic defects of the phalanges of the hand (HP:0009771)2.10932247
80Osteolytic defects of the hand bones (HP:0009699)2.10932247
81Peritonitis (HP:0002586)2.09315337
82Chronic otitis media (HP:0000389)2.07287465
83Malnutrition (HP:0004395)2.05627757
84Reduced antithrombin III activity (HP:0001976)2.04722461
85Vertigo (HP:0002321)2.03753481
86Abnormality of the pericardium (HP:0001697)2.03385968
87Abnormality of T cells (HP:0002843)2.02780767
88Cheilitis (HP:0100825)2.02666795
89Glomerulopathy (HP:0100820)2.02582471
90Recurrent skin infections (HP:0001581)2.01709160
91Abnormal hemoglobin (HP:0011902)1.99659393
92Chest pain (HP:0100749)1.98689794
93Panhypogammaglobulinemia (HP:0003139)1.98231710
94Complement deficiency (HP:0004431)1.97956302
95Nausea (HP:0002018)1.97114995
96Stomatitis (HP:0010280)1.96791105
97Menorrhagia (HP:0000132)1.96091485
98Reticulocytopenia (HP:0001896)1.96011158
99Pulmonary infiltrates (HP:0002113)1.95711111
100Aplastic anemia (HP:0001915)1.94710990
101Gingivitis (HP:0000230)1.94471280
102Increased IgE level (HP:0003212)1.94176189
103B lymphocytopenia (HP:0010976)1.93842590
104Chronic diarrhea (HP:0002028)1.92374628
105Abnormality of glutamine family amino acid metabolism (HP:0010902)1.91610756
106Colitis (HP:0002583)1.90621099
107Xerostomia (HP:0000217)1.89310815
108Thrombophlebitis (HP:0004418)1.89300130
109Recurrent bronchitis (HP:0002837)1.89241988
110Osteomyelitis (HP:0002754)1.88891975
111Prostate neoplasm (HP:0100787)1.88779702
112Abnormality of the distal phalanges of the toes (HP:0010182)1.87057987
113Skin ulcer (HP:0200042)1.86908912
114Abnormality of the intrinsic pathway (HP:0010989)1.86506859
115Increased neuronal autofluorescent lipopigment (HP:0002074)1.85610259
116Increased IgM level (HP:0003496)1.84987469
117Keratitis (HP:0000491)1.83164333
118Polycythemia (HP:0001901)1.82725424
119Hemoptysis (HP:0002105)1.82343257
120Abnormal platelet function (HP:0011869)1.82150148
121Impaired platelet aggregation (HP:0003540)1.82150148
122Purpura (HP:0000979)1.79158826
123Multiple enchondromatosis (HP:0005701)1.78972191
124Abnormality of proline metabolism (HP:0010907)1.78282890
125Hydroxyprolinuria (HP:0003080)1.78282890
126Cellulitis (HP:0100658)1.78038541
127Hypoglycemic coma (HP:0001325)1.77100408
12811 pairs of ribs (HP:0000878)1.76119875
129Encephalitis (HP:0002383)1.75746809
130Abnormality of the common coagulation pathway (HP:0010990)1.75551106
131Inflammation of the large intestine (HP:0002037)1.73796153
132Abnormality of the pleura (HP:0002103)1.72222753
133Abnormality of aromatic amino acid family metabolism (HP:0004338)1.71492171
134Urticaria (HP:0001025)1.70843204
135Spontaneous hematomas (HP:0007420)1.69627145
136Abnormality of the prostate (HP:0008775)1.69451094
137Myocardial infarction (HP:0001658)1.68653651
138Gastrointestinal inflammation (HP:0004386)1.67141704
139Abnormal delayed hypersensitivity skin test (HP:0002963)1.66780998
140Autoimmune hemolytic anemia (HP:0001890)1.66071985
141Alveolar cell carcinoma (HP:0006519)1.64607363
142Abnormal foot bone ossification (HP:0010675)1.64176494
143Focal segmental glomerulosclerosis (HP:0000097)1.63832129
144Granulocytopenia (HP:0001913)1.63301207
145Intrahepatic cholestasis (HP:0001406)1.62045045

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA23.94973139
2MAP3K142.89497844
3RIPK42.81665707
4MST42.59925426
5PIM22.51640414
6BMPR22.45108321
7IRAK32.27160756
8TBK12.23047886
9BMPR1B2.19083240
10JAK32.18135673
11MAP4K12.16071439
12RPS6KB22.11796983
13FRK2.09007692
14NME21.89927712
15GRK71.88993008
16MAP3K31.88720749
17TYK21.83554015
18TXK1.76101420
19ERN11.75687000
20IRAK41.72375651
21STK101.68647343
22IKBKE1.65913764
23IKBKB1.64927875
24TGFBR11.62731226
25TESK11.58384041
26LRRK21.54853694
27NEK91.52112857
28RPS6KA41.52016063
29FGR1.49481085
30MAP2K31.46391061
31FGFR41.45606431
32CHUK1.44738488
33SIK31.40258179
34KDR1.38128162
35EIF2AK31.37871819
36PAK41.35715767
37MST1R1.35558742
38IRAK11.33640099
39ZAP701.31687017
40TEC1.30437822
41TGFBR21.29766240
42PTK61.28564655
43PIM11.26247009
44LMTK21.25176906
45JAK11.17747554
46MAP2K21.17164398
47BTK1.13812164
48TAOK21.12486758
49FES1.07821526
50NUAK11.07003751
51EPHB11.05415517
52BLK1.01948718
53PBK1.01581846
54TAOK30.99072428
55MAP3K110.98760853
56ACVR1B0.97228087
57EPHA30.96347284
58FLT30.95043990
59PRKG20.94474487
60KIT0.93117450
61CSK0.92171979
62MATK0.91684036
63PDK20.91088966
64NLK0.90864448
65DDR20.89590965
66GRK60.89071858
67HCK0.88189737
68PASK0.87561573
69ADRBK20.85208276
70CDK60.85195337
71CDK80.84940733
72ZAK0.80085251
73MAP3K80.79825258
74IRAK20.79502310
75RIPK10.79018382
76MAP3K120.78739724
77PRPF4B0.77039981
78STK240.73185433
79JAK20.70997483
80TRPM70.70545657
81ERBB30.69364990
82TIE10.69142575
83CLK10.68861368
84SCYL20.68668106
85MAP3K10.65682689
86MYLK0.65024606
87EEF2K0.64692110
88STK30.63894971
89EIF2AK20.63411351
90STK40.62265068
91AURKB0.60772311
92BCKDK0.60160205
93BRSK20.59451731
94FGFR30.59174913
95PKN20.58448634
96MAPKAPK20.58103089
97ITK0.57930427
98DYRK1B0.57160182
99MAP3K130.56322497
100OXSR10.55194567
101PTK20.54930177
102EIF2AK10.54357583
103MOS0.53412328
104WEE10.52532763
105ERBB40.51191247
106PIK3CG0.51165966
107HIPK20.50652663
108CSF1R0.49711561
109FER0.49396555
110BMX0.49087552
111CDK40.48012436
112YES10.46884460
113LCK0.46749149
114MAP3K20.45963824
115MARK30.45917400
116LYN0.45471025
117CDC42BPA0.45243612
118TAOK10.44758185
119MAP2K60.44479768
120MAP3K50.44468214
121VRK10.44331324
122CDK70.43582873
123MAPKAPK30.42595155
124LATS10.42421098
125TESK20.42261544
126DYRK30.41396220
127ABL20.41058349
128SYK0.39225202
129TRIB30.37886848
130ATR0.37699375
131TNK20.36812910
132TRIM280.36670320
133EGFR0.35099520
134MAPK110.35095548
135* ABL10.33420836
136PRKCQ0.32935773

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.05591628
2Legionellosis_Homo sapiens_hsa051342.35389318
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.28451976
4Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.18934359
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.17041704
6Leishmaniasis_Homo sapiens_hsa051402.12954285
7Allograft rejection_Homo sapiens_hsa053302.07257845
8Intestinal immune network for IgA production_Homo sapiens_hsa046721.88797790
9NOD-like receptor signaling pathway_Homo sapiens_hsa046211.81182329
10Hematopoietic cell lineage_Homo sapiens_hsa046401.79885325
11Toll-like receptor signaling pathway_Homo sapiens_hsa046201.79599888
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.74329801
13Measles_Homo sapiens_hsa051621.73899958
14Pertussis_Homo sapiens_hsa051331.73434572
15TNF signaling pathway_Homo sapiens_hsa046681.67455760
16Malaria_Homo sapiens_hsa051441.59070948
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.54772198
18Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.54237566
19DNA replication_Homo sapiens_hsa030301.53295857
20Type I diabetes mellitus_Homo sapiens_hsa049401.45885226
21Folate biosynthesis_Homo sapiens_hsa007901.45511866
22Glutathione metabolism_Homo sapiens_hsa004801.40892209
23Caffeine metabolism_Homo sapiens_hsa002321.38916981
24Herpes simplex infection_Homo sapiens_hsa051681.36845128
25Asthma_Homo sapiens_hsa053101.33287916
26Ribosome_Homo sapiens_hsa030101.31393754
27Influenza A_Homo sapiens_hsa051641.31336748
28Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.30448705
29Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.28764433
30Antigen processing and presentation_Homo sapiens_hsa046121.27637652
31Rheumatoid arthritis_Homo sapiens_hsa053231.25660508
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.25499505
33Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.24602030
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.24489535
35Phagosome_Homo sapiens_hsa041451.23648903
36Toxoplasmosis_Homo sapiens_hsa051451.23570677
37Salmonella infection_Homo sapiens_hsa051321.22887680
38Chemical carcinogenesis_Homo sapiens_hsa052041.22212194
39Lysosome_Homo sapiens_hsa041421.21212223
40Pentose phosphate pathway_Homo sapiens_hsa000301.19793686
41Proteasome_Homo sapiens_hsa030501.19400630
42Apoptosis_Homo sapiens_hsa042101.17854327
43Staphylococcus aureus infection_Homo sapiens_hsa051501.17247927
44Sulfur metabolism_Homo sapiens_hsa009201.17155923
45One carbon pool by folate_Homo sapiens_hsa006701.14668028
46Small cell lung cancer_Homo sapiens_hsa052221.13788064
47Autoimmune thyroid disease_Homo sapiens_hsa053201.10909257
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.09445142
49Shigellosis_Homo sapiens_hsa051311.09306464
50Osteoclast differentiation_Homo sapiens_hsa043801.06880122
51Tuberculosis_Homo sapiens_hsa051521.05294516
52Selenocompound metabolism_Homo sapiens_hsa004501.04439088
53African trypanosomiasis_Homo sapiens_hsa051431.03902008
54B cell receptor signaling pathway_Homo sapiens_hsa046621.03611754
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01601625
56p53 signaling pathway_Homo sapiens_hsa041151.01268732
57Mismatch repair_Homo sapiens_hsa034301.00838736
58Chemokine signaling pathway_Homo sapiens_hsa040620.99495683
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.98180454
60Leukocyte transendothelial migration_Homo sapiens_hsa046700.97074437
61Hepatitis B_Homo sapiens_hsa051610.96965501
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.95548043
63Galactose metabolism_Homo sapiens_hsa000520.92873480
64Hepatitis C_Homo sapiens_hsa051600.92731262
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92586922
66Sulfur relay system_Homo sapiens_hsa041220.82236246
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82067840
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80935021
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80512153
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79601654
71Viral myocarditis_Homo sapiens_hsa054160.75509522
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75488656
73Amoebiasis_Homo sapiens_hsa051460.74932446
74Fructose and mannose metabolism_Homo sapiens_hsa000510.74476719
75Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.72804517
76Complement and coagulation cascades_Homo sapiens_hsa046100.72196500
77Pyrimidine metabolism_Homo sapiens_hsa002400.70560668
78Primary immunodeficiency_Homo sapiens_hsa053400.69079965
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68083391
80Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65092025
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64947761
82Base excision repair_Homo sapiens_hsa034100.63451729
83Systemic lupus erythematosus_Homo sapiens_hsa053220.61337550
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60892747
85Viral carcinogenesis_Homo sapiens_hsa052030.59935854
86Other glycan degradation_Homo sapiens_hsa005110.57726699
87Chronic myeloid leukemia_Homo sapiens_hsa052200.56803269
88Epstein-Barr virus infection_Homo sapiens_hsa051690.56593672
89Retinol metabolism_Homo sapiens_hsa008300.56447222
90Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56037109
91T cell receptor signaling pathway_Homo sapiens_hsa046600.53969087
92Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53925721
93Collecting duct acid secretion_Homo sapiens_hsa049660.53039380
94Starch and sucrose metabolism_Homo sapiens_hsa005000.52481543
95Vitamin digestion and absorption_Homo sapiens_hsa049770.51426151
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51130916
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.50527884
98Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.50398281
99Bladder cancer_Homo sapiens_hsa052190.49899970
100HTLV-I infection_Homo sapiens_hsa051660.49607254
101Protein export_Homo sapiens_hsa030600.47206972
102Acute myeloid leukemia_Homo sapiens_hsa052210.47187131
103Histidine metabolism_Homo sapiens_hsa003400.45362385
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44964393
105Mineral absorption_Homo sapiens_hsa049780.41422253
106Thyroid cancer_Homo sapiens_hsa052160.40662863
107Homologous recombination_Homo sapiens_hsa034400.39963861
108Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39470105
109Glycosaminoglycan degradation_Homo sapiens_hsa005310.38879160
110HIF-1 signaling pathway_Homo sapiens_hsa040660.38310317
111Adherens junction_Homo sapiens_hsa045200.37007429
112Renin-angiotensin system_Homo sapiens_hsa046140.36788152
113Cysteine and methionine metabolism_Homo sapiens_hsa002700.36715329
114ABC transporters_Homo sapiens_hsa020100.36217197
115Platelet activation_Homo sapiens_hsa046110.35990768
116Phenylalanine metabolism_Homo sapiens_hsa003600.34849105
117Tryptophan metabolism_Homo sapiens_hsa003800.33593001
118Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33214281
119Arachidonic acid metabolism_Homo sapiens_hsa005900.32930939
120Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30314824
121Prolactin signaling pathway_Homo sapiens_hsa049170.30213395
122Sphingolipid metabolism_Homo sapiens_hsa006000.28714873
123Pancreatic cancer_Homo sapiens_hsa052120.21961207
124Adipocytokine signaling pathway_Homo sapiens_hsa049200.19742178
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.19339021
126Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.18567527
127Dorso-ventral axis formation_Homo sapiens_hsa043200.15903830
128Endocytosis_Homo sapiens_hsa041440.14860187
129Primary bile acid biosynthesis_Homo sapiens_hsa001200.13748563
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.11920286
131Sphingolipid signaling pathway_Homo sapiens_hsa040710.07580780
132Prion diseases_Homo sapiens_hsa050200.07012333
133PPAR signaling pathway_Homo sapiens_hsa033200.05628958

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »