PLXNA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron projection extension involved in neuron projection guidance (GO:1902284)4.17870821
2axon extension involved in axon guidance (GO:0048846)4.17870821
3desmosome organization (GO:0002934)4.05316572
4gonadal mesoderm development (GO:0007506)3.98715190
5plasma membrane repair (GO:0001778)3.79669283
6apoptotic cell clearance (GO:0043277)3.63537215
7cytoskeletal anchoring at plasma membrane (GO:0007016)3.61910112
8protein retention in ER lumen (GO:0006621)3.59685709
9cell adhesion mediated by integrin (GO:0033627)3.56459463
10maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.50315359
11layer formation in cerebral cortex (GO:0021819)3.48817278
12Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.48138871
13polarized epithelial cell differentiation (GO:0030859)3.42186628
14protein heterotrimerization (GO:0070208)3.37943279
15regulation of hippo signaling (GO:0035330)3.36818103
16regulation of establishment of planar polarity (GO:0090175)3.30130898
17COPI coating of Golgi vesicle (GO:0048205)3.26842122
18Golgi transport vesicle coating (GO:0048200)3.26842122
19hippo signaling (GO:0035329)3.25839633
20convergent extension (GO:0060026)3.21622924
21negative regulation of fatty acid transport (GO:2000192)3.20479546
22regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.19872171
23pre-miRNA processing (GO:0031054)3.16076994
24* dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.11204742
25regulation of NFAT protein import into nucleus (GO:0051532)3.08773261
26basement membrane organization (GO:0071711)3.04677140
27stress fiber assembly (GO:0043149)3.04503713
28adherens junction assembly (GO:0034333)3.03706943
29endodermal cell differentiation (GO:0035987)3.03206245
30establishment of nucleus localization (GO:0040023)3.01083239
31regulation of axon extension involved in axon guidance (GO:0048841)3.00692125
32regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.99173579
33chondrocyte proliferation (GO:0035988)2.98635436
34anatomical structure regression (GO:0060033)2.98264806
35axon extension (GO:0048675)2.97862658
36NLS-bearing protein import into nucleus (GO:0006607)2.95330026
37establishment of apical/basal cell polarity (GO:0035089)2.93433408
38establishment of tissue polarity (GO:0007164)2.92645495
39establishment of planar polarity (GO:0001736)2.92645495
40wound healing, spreading of epidermal cells (GO:0035313)2.91414188
41cell-cell junction maintenance (GO:0045217)2.88268223
42planar cell polarity pathway involved in neural tube closure (GO:0090179)2.86214279
43establishment of monopolar cell polarity (GO:0061162)2.82723678
44establishment or maintenance of monopolar cell polarity (GO:0061339)2.82723678
45atrioventricular valve morphogenesis (GO:0003181)2.82497124
46regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.81915459
47branching involved in salivary gland morphogenesis (GO:0060445)2.81746135
48* semaphorin-plexin signaling pathway (GO:0071526)2.80334541
49glial cell proliferation (GO:0014009)2.80067491
50cochlea morphogenesis (GO:0090103)2.77881009
51cytoplasmic mRNA processing body assembly (GO:0033962)2.77262166
52non-canonical Wnt signaling pathway (GO:0035567)2.73844487
53insulin-like growth factor receptor signaling pathway (GO:0048009)2.72470443
54neural tube development (GO:0021915)2.70840649
55neuron projection extension (GO:1990138)2.69746655
56negative regulation of axon extension involved in axon guidance (GO:0048843)2.69608497
57camera-type eye morphogenesis (GO:0048593)2.69585686
58positive regulation of axon extension (GO:0045773)2.68963080
59regulation of early endosome to late endosome transport (GO:2000641)2.68491849
60cell-substrate junction assembly (GO:0007044)2.67655471
61negative regulation of cell size (GO:0045792)2.65938002
62endothelial cell morphogenesis (GO:0001886)2.65860866
63epithelial cell differentiation involved in prostate gland development (GO:0060742)2.65242414
64regulation of axon guidance (GO:1902667)2.64991991
65negative regulation of catenin import into nucleus (GO:0035414)2.63814094
66embryonic foregut morphogenesis (GO:0048617)2.63161349
67heterochromatin organization (GO:0070828)2.63137952
68establishment or maintenance of apical/basal cell polarity (GO:0035088)2.63086076
69establishment or maintenance of bipolar cell polarity (GO:0061245)2.63086076
70regulation of integrin activation (GO:0033623)2.62706526
71barbed-end actin filament capping (GO:0051016)2.61208966
72regulation of glucose import in response to insulin stimulus (GO:2001273)2.58997331
73endothelial cell chemotaxis (GO:0035767)2.58081461
74positive regulation of SMAD protein import into nucleus (GO:0060391)2.58074415
75retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.56164862
76positive regulation of fibroblast migration (GO:0010763)2.55876947
77collagen fibril organization (GO:0030199)2.55359272
78paraxial mesoderm development (GO:0048339)2.55097432
79regulation of SMAD protein import into nucleus (GO:0060390)2.54845643
80protein localization to endosome (GO:0036010)2.54177074
81cellular response to interferon-alpha (GO:0035457)2.53478581
82fibroblast migration (GO:0010761)2.53082406
83germ cell migration (GO:0008354)2.52008669
84extracellular matrix disassembly (GO:0022617)2.51757890
85epithelial cell-cell adhesion (GO:0090136)2.50306406
86positive regulation of male gonad development (GO:2000020)2.49472776
87synaptic vesicle docking involved in exocytosis (GO:0016081)2.49462508
88heparan sulfate proteoglycan metabolic process (GO:0030201)2.48584485
89negative regulation of cartilage development (GO:0061037)2.47299247
90activation of Rac GTPase activity (GO:0032863)2.46111659
91apoptotic process involved in morphogenesis (GO:0060561)2.44872246
92vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.44553187
93positive regulation of endothelial cell apoptotic process (GO:2000353)2.44417638
94cell junction assembly (GO:0034329)2.43526721
95facial nerve structural organization (GO:0021612)2.42708615
96endocytic recycling (GO:0032456)2.42673262
97gastrulation with mouth forming second (GO:0001702)2.42440711
98cell migration in hindbrain (GO:0021535)2.42398614
99mesodermal cell differentiation (GO:0048333)2.41779476
100peptidyl-lysine dimethylation (GO:0018027)2.40798539
101clathrin coat assembly (GO:0048268)2.40370510
102apical protein localization (GO:0045176)2.40066746
103G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.38963297
104negative regulation of chondrocyte differentiation (GO:0032331)2.38177046
105regulation of cardioblast differentiation (GO:0051890)2.38004843
106developmental cell growth (GO:0048588)2.37946985
107regulation of mammary gland epithelial cell proliferation (GO:0033599)2.37859349
108hemidesmosome assembly (GO:0031581)2.37833874
109regulation of clathrin-mediated endocytosis (GO:2000369)2.37460686
110ovulation cycle (GO:0042698)2.37191417
111glial cell migration (GO:0008347)2.36075591
112eye morphogenesis (GO:0048592)2.35874464
113cell-substrate adherens junction assembly (GO:0007045)2.35230377
114focal adhesion assembly (GO:0048041)2.35230377
115cell migration involved in heart development (GO:0060973)2.33945908
116glomerular basement membrane development (GO:0032836)2.33839181
117muscle cell migration (GO:0014812)2.33781456
118glucocorticoid receptor signaling pathway (GO:0042921)2.32703047
119vascular endothelial growth factor signaling pathway (GO:0038084)2.32553790
120macroautophagy (GO:0016236)2.32333768
121cell junction organization (GO:0034330)2.31683512
122dendrite morphogenesis (GO:0048813)2.31359399
123establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.29730909
124endocardial cushion development (GO:0003197)2.29621707
125bone trabecula formation (GO:0060346)2.29244367
126adherens junction organization (GO:0034332)2.28864399
127regulation of tight junction assembly (GO:2000810)2.26764474
128positive regulation of p38MAPK cascade (GO:1900745)2.25432311
129craniofacial suture morphogenesis (GO:0097094)2.24888921
130sodium ion export (GO:0071436)2.24827064
131positive regulation of dendrite morphogenesis (GO:0050775)2.24572282
132heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.23389708
133collagen metabolic process (GO:0032963)2.22482476
134actin filament bundle organization (GO:0061572)2.22275644
135actin filament bundle assembly (GO:0051017)2.22275644
136collagen catabolic process (GO:0030574)2.22256248
137positive regulation of macrophage cytokine production (GO:0060907)2.21252437
138substrate adhesion-dependent cell spreading (GO:0034446)2.21169579
139regulation of gene silencing by RNA (GO:0060966)2.19590453
140regulation of posttranscriptional gene silencing (GO:0060147)2.19590453
141regulation of gene silencing by miRNA (GO:0060964)2.19590453
142skin morphogenesis (GO:0043589)2.19094845
143cortical actin cytoskeleton organization (GO:0030866)2.18990219
144regulation of p38MAPK cascade (GO:1900744)2.16623726
145vagina development (GO:0060068)2.15966068
146multicellular organismal macromolecule metabolic process (GO:0044259)2.15361091
147substrate-dependent cell migration (GO:0006929)2.15302778

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human3.82816320
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.62640262
3STAT6_21828071_ChIP-Seq_BEAS2B_Human2.93750890
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.89128017
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.61729466
6ZFP281_18757296_ChIP-ChIP_E14_Mouse2.49600595
7WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.45320741
8SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.37807697
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.36961431
10* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.32960252
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.20112408
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.17449718
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.16558677
14KDM2B_26808549_Chip-Seq_K562_Human2.14439495
15ZFP281_27345836_Chip-Seq_ESCs_Mouse2.11651107
16* TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.08573410
17* KDM2B_26808549_Chip-Seq_DND41_Human2.07548166
18EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.01093764
19* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.97302588
20P300_27058665_Chip-Seq_ZR-75-30cells_Human1.95932613
21DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.91868413
22SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.89365213
23* ELK3_25401928_ChIP-Seq_HUVEC_Human1.83903609
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.83731329
25* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.70092530
26ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.68218586
27CLOCK_20551151_ChIP-Seq_293T_Human1.67577857
28TCF7_22412390_ChIP-Seq_EML_Mouse1.64493545
29FOXM1_23109430_ChIP-Seq_U2OS_Human1.61690630
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.61639774
31HIF1A_21447827_ChIP-Seq_MCF-7_Human1.60347213
32TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.60092005
33* KDM2B_26808549_Chip-Seq_JURKAT_Human1.59722472
34* LXR_22292898_ChIP-Seq_THP-1_Human1.58309123
35* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52713985
36TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.52439078
37* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.52363302
38KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52289565
39ESR2_21235772_ChIP-Seq_MCF-7_Human1.50219461
40ZNF263_19887448_ChIP-Seq_K562_Human1.49839949
41RACK7_27058665_Chip-Seq_MCF-7_Human1.48455130
42TP53_22127205_ChIP-Seq_IMR90_Human1.44367879
43NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.37822361
44UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.35040659
45MYC_22102868_ChIP-Seq_BL_Human1.34591826
46TET1_21490601_ChIP-Seq_MESCs_Mouse1.33677539
47DROSHA_22980978_ChIP-Seq_HELA_Human1.33413176
48ATF3_27146783_Chip-Seq_COLON_Human1.33349977
49CTCF_27219007_Chip-Seq_Bcells_Human1.30845815
50KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.30075408
51TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30067552
52TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29424753
53OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29033105
54ESR1_21235772_ChIP-Seq_MCF-7_Human1.28457425
55ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28136681
56KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27524948
57ERG_21242973_ChIP-ChIP_JURKAT_Human1.26255726
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.25356802
59SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23667986
60* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.22331780
61* BRD4_25478319_ChIP-Seq_HGPS_Human1.22228960
62FOXO3_23340844_ChIP-Seq_DLD1_Human1.21999297
63ISL1_27105846_Chip-Seq_CPCs_Mouse1.21921648
64TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.20773079
65ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20416261
66FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.19777994
67CREB1_26743006_Chip-Seq_LNCaP_Human1.19768715
68SOX9_24532713_ChIP-Seq_HFSC_Mouse1.19553061
69DNAJC2_21179169_ChIP-ChIP_NT2_Human1.19406913
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.19034539
71JARID2_20075857_ChIP-Seq_MESCs_Mouse1.19034250
72SMC4_20622854_ChIP-Seq_HELA_Human1.18557589
73* TP53_23651856_ChIP-Seq_MEFs_Mouse1.17701842
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.17334883
75EED_16625203_ChIP-ChIP_MESCs_Mouse1.17187087
76SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16287706
77NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.16020978
78TET1_21451524_ChIP-Seq_MESCs_Mouse1.14556409
79TP53_16413492_ChIP-PET_HCT116_Human1.14077764
80DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13604165
81ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13477768
82* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12889457
83NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11764571
84PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11342314
85SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.10105255
86P63_26484246_Chip-Seq_KERATINOCYTES_Human1.09758090
87SA1_27219007_Chip-Seq_ERYTHROID_Human1.09631071
88RNF2_18974828_ChIP-Seq_MESCs_Mouse1.08657880
89EZH2_18974828_ChIP-Seq_MESCs_Mouse1.08657880
90* RUNX1_27514584_Chip-Seq_MCF-7_Human1.08554150
91SUZ12_27294783_Chip-Seq_ESCs_Mouse1.08452281
92SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.07185431
93KLF5_25053715_ChIP-Seq_YYC3_Human1.06860555
94EZH2_27294783_Chip-Seq_ESCs_Mouse1.06780861
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06593917
96UBF1/2_26484160_Chip-Seq_HMECs_Human1.06356481
97SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.06115874
98SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.06115874
99FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.05229707
100SALL1_21062744_ChIP-ChIP_HESCs_Human1.05195504
101CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05023877
102* TP53_20018659_ChIP-ChIP_R1E_Mouse1.04869799
103PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.04703186
104* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.04459478
105SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04363025
106MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04268765
107EZH2_27304074_Chip-Seq_ESCs_Mouse1.04036269
108THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03951825
109MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.03580744
110ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.01751247
111AHR_22903824_ChIP-Seq_MCF-7_Human1.01326285
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01113000
113EP300_21415370_ChIP-Seq_HL-1_Mouse1.00184638
114CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.99870696
115TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.99753884
116P68_20966046_ChIP-Seq_HELA_Human0.99669464
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99572294
118KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.99262849
119KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.99262849
120KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.99262849
121CJUN_26792858_Chip-Seq_BT549_Human0.98511870
122TP63_22573176_ChIP-Seq_HFKS_Human0.98409596
123CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98305938
124IKZF1_21737484_ChIP-ChIP_HCT116_Human0.97885991
125RNF2_27304074_Chip-Seq_ESCs_Mouse0.97793233
126RING1B_27294783_Chip-Seq_NPCs_Mouse0.97629144
127PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.97493050
128VDR_21846776_ChIP-Seq_THP-1_Human0.97096637
129ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96822415
130NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.96643408
131TBX20_22328084_ChIP-Seq_HEART_Mouse0.96188345
132TBX20_22080862_ChIP-Seq_HEART_Mouse0.96188345
133VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.95981120
134SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.95403835
135RARB_27405468_Chip-Seq_BRAIN_Mouse0.95401125

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.44211961
2MP0000569_abnormal_digit_pigmentation4.23056249
3MP0008438_abnormal_cutaneous_collagen4.02788243
4MP0005623_abnormal_meninges_morphology3.19018199
5MP0005257_abnormal_intraocular_pressure3.10849149
6MP0000579_abnormal_nail_morphology2.93547598
7MP0005076_abnormal_cell_differentiation2.69008388
8MP0001958_emphysema2.59897355
9MP0010352_gastrointestinal_tract_polyps2.49056526
10MP0004858_abnormal_nervous_system2.47407715
11MP0005409_darkened_coat_color2.39819872
12MP0005275_abnormal_skin_tensile2.37899385
13MP0003566_abnormal_cell_adhesion2.20666861
14MP0004272_abnormal_basement_membrane2.11167528
15MP0009780_abnormal_chondrocyte_physiolo2.08242009
16MP0000733_abnormal_muscle_development2.06473821
17MP0003091_abnormal_cell_migration2.01651623
18MP0003283_abnormal_digestive_organ1.94241883
19MP0004859_abnormal_synaptic_plasticity1.91086495
20MP0000566_synostosis1.88054437
21MP0000537_abnormal_urethra_morphology1.75995159
22MP0010030_abnormal_orbit_morphology1.74436427
23MP0005503_abnormal_tendon_morphology1.72206943
24MP0000762_abnormal_tongue_morphology1.72055976
25MP0001849_ear_inflammation1.68230844
26MP0009278_abnormal_bone_marrow1.66696534
27MP0003453_abnormal_keratinocyte_physiol1.61651257
28MP0003279_aneurysm1.59371300
29MP0004233_abnormal_muscle_weight1.54688991
30MP0003303_peritoneal_inflammation1.49632904
31MP0010234_abnormal_vibrissa_follicle1.49453319
32MP0003115_abnormal_respiratory_system1.46634865
33MP0010307_abnormal_tumor_latency1.44792740
34MP0003385_abnormal_body_wall1.44406149
35MP0000428_abnormal_craniofacial_morphol1.42768765
36MP0003045_fibrosis1.41453057
37MP0003172_abnormal_lysosome_physiology1.39289802
38MP0001299_abnormal_eye_distance/1.38711004
39MP0002249_abnormal_larynx_morphology1.35825892
40MP0000467_abnormal_esophagus_morphology1.35660605
41MP0000751_myopathy1.33148268
42MP0001348_abnormal_lacrimal_gland1.32055770
43MP0005248_abnormal_Harderian_gland1.27511441
44MP0000534_abnormal_ureter_morphology1.25494313
45MP0009053_abnormal_anal_canal1.22176502
46MP0002877_abnormal_melanocyte_morpholog1.21361358
47MP0005023_abnormal_wound_healing1.21082162
48MP0002796_impaired_skin_barrier1.20174005
49MP0005058_abnormal_lysosome_morphology1.18977278
50MP0004197_abnormal_fetal_growth/weight/1.16179421
51MP0005508_abnormal_skeleton_morphology1.15273494
52MP0003119_abnormal_digestive_system1.14475144
53MP0003300_gastrointestinal_ulcer1.14154668
54MP0002089_abnormal_postnatal_growth/wei1.13678763
55MP0000678_abnormal_parathyroid_gland1.12975147
56MP0000371_diluted_coat_color1.08893731
57MP0003878_abnormal_ear_physiology1.08017384
58MP0005377_hearing/vestibular/ear_phenot1.08017384
59MP0002896_abnormal_bone_mineralization1.06589569
60MP0000462_abnormal_digestive_system1.03938574
61MP0002084_abnormal_developmental_patter1.03805487
62MP0003942_abnormal_urinary_system1.02950545
63MP0002098_abnormal_vibrissa_morphology1.01944874
64MP0003941_abnormal_skin_development1.00095977
65MP0003123_paternal_imprinting1.00076006
66MP0010368_abnormal_lymphatic_system1.00040923
67MP0003935_abnormal_craniofacial_develop0.98745524
68MP0003755_abnormal_palate_morphology0.97114962
69MP0005171_absent_coat_pigmentation0.95698083
70MP0004185_abnormal_adipocyte_glucose0.94283482
71MP0005501_abnormal_skin_physiology0.93930225
72MP0002697_abnormal_eye_size0.93315509
73MP0001216_abnormal_epidermal_layer0.93182589
74MP0000759_abnormal_skeletal_muscle0.92619133
75MP0000767_abnormal_smooth_muscle0.90886122
76MP0001915_intracranial_hemorrhage0.90843015
77MP0002925_abnormal_cardiovascular_devel0.90670760
78MP0002092_abnormal_eye_morphology0.90606210
79MP0009384_cardiac_valve_regurgitation0.90412055
80MP0002168_other_aberrant_phenotype0.89501048
81MP0000778_abnormal_nervous_system0.89412867
82MP0004087_abnormal_muscle_fiber0.89168677
83MP0000432_abnormal_head_morphology0.88043275
84* MP0003634_abnormal_glial_cell0.87679532
85MP0002295_abnormal_pulmonary_circulatio0.86689032
86MP0000516_abnormal_urinary_system0.86659190
87MP0005367_renal/urinary_system_phenotyp0.86659190
88MP0003448_altered_tumor_morphology0.85369238
89MP0009250_abnormal_appendicular_skeleto0.84990219
90MP0005451_abnormal_body_composition0.84685608
91MP0009840_abnormal_foam_cell0.84180459
92MP0000013_abnormal_adipose_tissue0.83429693
93MP0000377_abnormal_hair_follicle0.82274359
94MP0002085_abnormal_embryonic_tissue0.81937153
95MP0000750_abnormal_muscle_regeneration0.81897813
96MP0002653_abnormal_ependyma_morphology0.81356611
97MP0002254_reproductive_system_inflammat0.81314259
98MP0008961_abnormal_basal_metabolism0.80539029
99MP0002116_abnormal_craniofacial_bone0.79894801
100MP0004270_analgesia0.79630768
101MP0000049_abnormal_middle_ear0.79478331
102MP0005197_abnormal_uvea_morphology0.79429291
103MP0002060_abnormal_skin_morphology0.78837588
104MP0010771_integument_phenotype0.78761888
105MP0003861_abnormal_nervous_system0.78379473
106MP0004510_myositis0.78222637
107MP0010630_abnormal_cardiac_muscle0.77480245
108MP0002234_abnormal_pharynx_morphology0.77156507
109MP0001243_abnormal_dermal_layer0.76595989
110MP0001542_abnormal_bone_strength0.76498278
111MP0002086_abnormal_extraembryonic_tissu0.76402762
112MP0006054_spinal_hemorrhage0.75268826
113MP0002108_abnormal_muscle_morphology0.73826196
114MP0002233_abnormal_nose_morphology0.71976065
115MP0000003_abnormal_adipose_tissue0.71205910
116MP0000749_muscle_degeneration0.71163793
117MP0002177_abnormal_outer_ear0.71127686
118MP0006138_congestive_heart_failure0.70849529
119MP0008770_decreased_survivor_rate0.69830560
120MP0002114_abnormal_axial_skeleton0.69707253
121MP0003937_abnormal_limbs/digits/tail_de0.69664756
122MP0001730_embryonic_growth_arrest0.69479143
123MP0002282_abnormal_trachea_morphology0.69236458
124MP0000747_muscle_weakness0.69001804
125MP0002932_abnormal_joint_morphology0.68700938
126MP0001293_anophthalmia0.68385091
127MP0009672_abnormal_birth_weight0.68099363
128MP0001614_abnormal_blood_vessel0.66297292
129MP0003329_amyloid_beta_deposits0.66226505
130MP0004084_abnormal_cardiac_muscle0.65787014
131MP0004811_abnormal_neuron_physiology0.65449477
132MP0002128_abnormal_blood_circulation0.65241143
133MP0001340_abnormal_eyelid_morphology0.64798088
134MP0002111_abnormal_tail_morphology0.64337375
135MP0005193_abnormal_anterior_eye0.64292329
136MP0002088_abnormal_embryonic_growth/wei0.64227053

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.32360560
2Shallow orbits (HP:0000586)3.88691874
3Premature rupture of membranes (HP:0001788)3.75863583
4Ankle contracture (HP:0006466)3.62376287
5Cerebral aneurysm (HP:0004944)3.53220905
6Bladder diverticulum (HP:0000015)3.05075081
7Distal upper limb amyotrophy (HP:0007149)2.97218485
8Upper limb amyotrophy (HP:0009129)2.97218485
9Hand muscle atrophy (HP:0009130)2.86560800
10Hyperacusis (HP:0010780)2.72324830
11Short 4th metacarpal (HP:0010044)2.72075492
12Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.72075492
13Milia (HP:0001056)2.69992612
14Broad face (HP:0000283)2.69389670
15Genu recurvatum (HP:0002816)2.69226125
16Natal tooth (HP:0000695)2.60974382
17Atrophic scars (HP:0001075)2.56824133
18Subacute progressive viral hepatitis (HP:0006572)2.55429753
19Mitral valve prolapse (HP:0001634)2.47068951
20Fragile nails (HP:0001808)2.45577482
21Bowel diverticulosis (HP:0005222)2.44079233
22Dilatation of the ascending aorta (HP:0005111)2.41678827
23Wrist flexion contracture (HP:0001239)2.34027040
24Short nail (HP:0001799)2.33687873
25Broad metatarsal (HP:0001783)2.30740122
26Aortic dissection (HP:0002647)2.28550355
27Renal duplication (HP:0000075)2.27122030
28Disproportionate tall stature (HP:0001519)2.27044225
29Pterygium (HP:0001059)2.26966539
30Obstructive sleep apnea (HP:0002870)2.26320836
31Increased connective tissue (HP:0009025)2.22323797
32Vertebral compression fractures (HP:0002953)2.21991710
33Increased cerebral lipofuscin (HP:0011813)2.19720377
34Turricephaly (HP:0000262)2.19566348
35Neurofibrillary tangles (HP:0002185)2.17297056
36Aortic aneurysm (HP:0004942)2.15129229
37Advanced eruption of teeth (HP:0006288)2.13707900
38Deviation of the hallux (HP:0010051)2.13442236
39Hallux valgus (HP:0001822)2.11426414
40Astrocytoma (HP:0009592)2.10213224
41Abnormality of the astrocytes (HP:0100707)2.10213224
42Cervical subluxation (HP:0003308)2.09160349
43Fragile skin (HP:0001030)2.09137787
44Renovascular hypertension (HP:0100817)2.07118738
45Peritonitis (HP:0002586)2.06612415
46Abnormality of the 4th metacarpal (HP:0010012)2.06521351
47Macroorchidism (HP:0000053)2.05824210
48Lower limb amyotrophy (HP:0007210)2.03268125
49Neonatal short-limb short stature (HP:0008921)2.03035304
50Abnormality of the lower motor neuron (HP:0002366)2.00773296
51Lymphangioma (HP:0100764)2.00554080
52Ulnar bowing (HP:0003031)2.00519327
53Aplasia involving bones of the extremities (HP:0009825)2.00448726
54Aplasia involving bones of the upper limbs (HP:0009823)2.00448726
55Aplasia of the phalanges of the hand (HP:0009802)2.00448726
56Biconcave vertebral bodies (HP:0004586)1.96220881
57Aneurysm (HP:0002617)1.94599520
58Thick nail (HP:0001805)1.93392851
59Pointed chin (HP:0000307)1.92866865
60Disinhibition (HP:0000734)1.92856050
61Elfin facies (HP:0004428)1.92330142
62Elbow flexion contracture (HP:0002987)1.88075049
63Abnormality of the Achilles tendon (HP:0005109)1.87248057
64Thin ribs (HP:0000883)1.87030893
65Apathy (HP:0000741)1.86509753
66Wormian bones (HP:0002645)1.84638856
67Buphthalmos (HP:0000557)1.84259467
68Insomnia (HP:0100785)1.84180607
69Heterotopia (HP:0002282)1.84094792
70Difficulty climbing stairs (HP:0003551)1.84025648
71Distal lower limb muscle weakness (HP:0009053)1.83591556
72Abnormality of the distal phalanx of the thumb (HP:0009617)1.83425020
73Absent frontal sinuses (HP:0002688)1.82768524
74Supranuclear gaze palsy (HP:0000605)1.81315272
75Long toe (HP:0010511)1.80389148
76Long palpebral fissure (HP:0000637)1.80364501
77Increased density of long bones (HP:0006392)1.79860492
78Soft skin (HP:0000977)1.79824336
79Flat cornea (HP:0007720)1.79728213
80Flat acetabular roof (HP:0003180)1.79634558
81Hyperextensible skin (HP:0000974)1.79085971
82Spinal rigidity (HP:0003306)1.77628583
83Abnormality of dentin (HP:0010299)1.75863076
84Abnormality of the distal phalanges of the toes (HP:0010182)1.75751167
85Diminished motivation (HP:0000745)1.75362850
86Vertebral arch anomaly (HP:0008438)1.74573076
87Thin bony cortex (HP:0002753)1.74560523
88Blue sclerae (HP:0000592)1.74261493
89Mildly elevated creatine phosphokinase (HP:0008180)1.74148515
90Enlarged penis (HP:0000040)1.74143187
91Overriding aorta (HP:0002623)1.73191794
92Alopecia of scalp (HP:0002293)1.73015683
93Type 1 muscle fiber predominance (HP:0003803)1.72447252
94Difficulty running (HP:0009046)1.72426085
95Bowing of the arm (HP:0006488)1.70725966
96Bowed forearm bones (HP:0003956)1.70725966
97Increased variability in muscle fiber diameter (HP:0003557)1.70482891
98Ankyloglossia (HP:0010296)1.70068690
99Nail dystrophy (HP:0008404)1.69791868
100Joint laxity (HP:0001388)1.69753037
101Abnormality of nail color (HP:0100643)1.69254712
102Patellar dislocation (HP:0002999)1.68781377
103Scapular winging (HP:0003691)1.68213166
104Bronchomalacia (HP:0002780)1.67614517
105Germ cell neoplasia (HP:0100728)1.66763066
106Osteolytic defects of the hand bones (HP:0009699)1.65546056
107Osteolytic defects of the phalanges of the hand (HP:0009771)1.65546056
108Wide anterior fontanel (HP:0000260)1.64835992
109Striae distensae (HP:0001065)1.64557759
110Coronal craniosynostosis (HP:0004440)1.64264140
111Fibroma (HP:0010614)1.64237172
112Onycholysis (HP:0001806)1.64109235
113Distal lower limb amyotrophy (HP:0008944)1.63709717
114Overgrowth (HP:0001548)1.62596124
115Follicular hyperkeratosis (HP:0007502)1.62427418
116Camptodactyly of toe (HP:0001836)1.62104650
117Cerebral inclusion bodies (HP:0100314)1.61848404
118Stridor (HP:0010307)1.61582669
119Radial bowing (HP:0002986)1.61450013
120Leiomyosarcoma (HP:0100243)1.60793116
121Uterine leiomyosarcoma (HP:0002891)1.60793116
122Narrow palate (HP:0000189)1.60419182
123Achilles tendon contracture (HP:0001771)1.60174424
124Right ventricular cardiomyopathy (HP:0011663)1.59713905
125Abnormality of skeletal muscle fiber size (HP:0012084)1.59236574
126Broad thumb (HP:0011304)1.58882691
127Arnold-Chiari malformation (HP:0002308)1.58009035
128Fibrous tissue neoplasm (HP:0012316)1.56094704
129Vascular tortuosity (HP:0004948)1.55551611
130Abnormality of the peritoneum (HP:0002585)1.54729975
131Frequent falls (HP:0002359)1.53202305
132Male infertility (HP:0003251)1.52969040
133Selective tooth agenesis (HP:0001592)1.52187030
134Hypoventilation (HP:0002791)1.52154477
135Arterial tortuosity (HP:0005116)1.50408945
136Mitral regurgitation (HP:0001653)1.49934382
137Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.49372861
138Inappropriate behavior (HP:0000719)1.49201619
139Rectal prolapse (HP:0002035)1.48246713

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.10234183
2CDK123.21982286
3PKN23.17956988
4RIPK12.99524677
5TTN2.91049952
6LATS22.85637663
7DDR22.47380639
8PDGFRA2.39714951
9MARK12.22260481
10LATS12.20062369
11ICK2.10988151
12SMG12.10711121
13MAP3K92.09955790
14BMX2.06791929
15TYRO32.02931990
16EEF2K1.93529751
17MAP3K101.91358500
18IRAK31.85053657
19PTK61.83883304
20PRKD31.71856688
21PAK61.70557527
22CAMK1D1.65051898
23SCYL21.64161050
24CAMK1G1.62731782
25EPHB21.49739820
26MTOR1.48417113
27FGFR41.37281755
28PTK21.37088922
29PAK41.36929416
30SIK21.36210579
31ERN11.32931574
32PAK21.28017548
33KSR21.27478197
34DAPK21.27190049
35ALK1.20489773
36EPHB11.19205743
37PRPF4B1.15391513
38DMPK1.12172228
39CAMKK11.08640756
40MAP3K61.08085893
41ARAF1.07664802
42PDGFRB1.04625532
43FGFR11.02399243
44RET1.01283269
45KSR10.98417391
46PRKD20.98410571
47CDK60.94669847
48NTRK10.94611706
49BRD40.93619095
50PAK30.93043574
51SIK10.91796079
52MET0.91131195
53TAOK10.90662389
54FER0.89897815
55MST1R0.87842792
56MINK10.87738450
57EPHA20.86394803
58STK380.84167429
59MAP3K40.82871004
60NME20.82345888
61NEK10.80488541
62ERBB30.78025916
63PHKG10.74428968
64PHKG20.74428968
65ERBB40.74406310
66STK30.72491217
67RPS6KA20.67757869
68PTK2B0.66602410
69NEK20.65522203
70CDC42BPA0.64200092
71PIM20.62625871
72MAP3K20.62493268
73PRKCH0.62021692
74NTRK20.61495490
75LRRK20.61003191
76ROCK20.60072864
77FGR0.60024990
78ERBB20.59007995
79RPS6KC10.57802926
80RPS6KL10.57802926
81LMTK20.57611526
82TESK10.57352687
83DAPK30.56829867
84EPHA40.56699406
85ROCK10.56508748
86MARK20.55308540
87ILK0.53240151
88BRAF0.53237792
89MYLK0.51926391
90MAP3K30.51333293
91EGFR0.49682346
92FGFR30.49140384
93PLK20.48817007
94NTRK30.47623078
95MOS0.47386956
96SRC0.46159030
97CDK150.44397690
98CSNK1A1L0.43727190
99TGFBR20.43553052
100CDK140.41496381
101MAP2K10.40579495
102TAOK20.39858037
103MAP3K70.39744903
104FYN0.39061847
105CDK180.39036836
106CDK50.38868702
107CSNK1D0.38317900
108ABL20.37423035
109LIMK10.37113779
110RPS6KA60.36604513
111MAP3K80.36483488
112SGK30.35409449
113PRKG20.35206763
114CDK40.34979423
115CDK11A0.34857493
116CDK90.34580746
117INSR0.34209444
118MAPK100.33729731
119CASK0.33702585
120PRKD10.33644785
121CAMK2G0.33436354
122MAPK80.33382159
123STK110.33380379
124PDPK10.33307244
125CSNK1G20.33204836
126AKT20.32992976
127FGFR20.32872832
128DAPK10.32830290
129CDK70.32591227
130MUSK0.30376213
131FLT30.28550214
132NEK90.27939111
133CLK10.27762846
134CAMK2B0.27659706

Predicted pathways (KEGG)

RankGene SetZ-score
1Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.82446726
2ECM-receptor interaction_Homo sapiens_hsa045121.82215812
3Focal adhesion_Homo sapiens_hsa045101.81269396
4Proteoglycans in cancer_Homo sapiens_hsa052051.70817097
5Adherens junction_Homo sapiens_hsa045201.62471085
6Glioma_Homo sapiens_hsa052141.59162224
7Chronic myeloid leukemia_Homo sapiens_hsa052201.57255752
8Amoebiasis_Homo sapiens_hsa051461.55221130
9Hippo signaling pathway_Homo sapiens_hsa043901.53432303
10mTOR signaling pathway_Homo sapiens_hsa041501.50891689
11Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.48801405
12Basal cell carcinoma_Homo sapiens_hsa052171.47926821
13Prion diseases_Homo sapiens_hsa050201.46208483
14MicroRNAs in cancer_Homo sapiens_hsa052061.44538253
15Endometrial cancer_Homo sapiens_hsa052131.42502248
16Small cell lung cancer_Homo sapiens_hsa052221.39217366
17AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.34856957
18Viral myocarditis_Homo sapiens_hsa054161.31938202
19* Axon guidance_Homo sapiens_hsa043601.31934102
20Colorectal cancer_Homo sapiens_hsa052101.31481164
21Notch signaling pathway_Homo sapiens_hsa043301.30710283
22Dorso-ventral axis formation_Homo sapiens_hsa043201.30434883
23Bladder cancer_Homo sapiens_hsa052191.29776911
24Neurotrophin signaling pathway_Homo sapiens_hsa047221.29590116
25Hedgehog signaling pathway_Homo sapiens_hsa043401.26674971
26Central carbon metabolism in cancer_Homo sapiens_hsa052301.25414431
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.24351222
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.21749258
29Thyroid cancer_Homo sapiens_hsa052161.21564804
30Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.19950496
31Thyroid hormone signaling pathway_Homo sapiens_hsa049191.19243232
32Estrogen signaling pathway_Homo sapiens_hsa049151.18939815
33Renal cell carcinoma_Homo sapiens_hsa052111.18702674
34Other glycan degradation_Homo sapiens_hsa005111.18406379
35Regulation of actin cytoskeleton_Homo sapiens_hsa048101.16169334
36Dilated cardiomyopathy_Homo sapiens_hsa054141.15821097
37VEGF signaling pathway_Homo sapiens_hsa043701.14260360
38Melanogenesis_Homo sapiens_hsa049161.12516883
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.12246141
40Pancreatic cancer_Homo sapiens_hsa052121.12165724
41Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.12031863
42Type II diabetes mellitus_Homo sapiens_hsa049301.10092820
43TGF-beta signaling pathway_Homo sapiens_hsa043501.08251406
44Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.06933756
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.04733532
46ErbB signaling pathway_Homo sapiens_hsa040121.03482478
47Glycosaminoglycan degradation_Homo sapiens_hsa005311.01899868
48Tight junction_Homo sapiens_hsa045301.00448199
49Gap junction_Homo sapiens_hsa045400.99386902
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.98791517
51Lysosome_Homo sapiens_hsa041420.97970242
52Melanoma_Homo sapiens_hsa052180.97941771
53GnRH signaling pathway_Homo sapiens_hsa049120.96710311
54Non-small cell lung cancer_Homo sapiens_hsa052230.96568734
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96141121
56Rap1 signaling pathway_Homo sapiens_hsa040150.96042209
57Vibrio cholerae infection_Homo sapiens_hsa051100.94971415
58Synaptic vesicle cycle_Homo sapiens_hsa047210.94005257
59Toxoplasmosis_Homo sapiens_hsa051450.93928980
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.93755580
61Longevity regulating pathway - mammal_Homo sapiens_hsa042110.92581676
62Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.91579165
63Salmonella infection_Homo sapiens_hsa051320.89843982
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.89223440
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87988687
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.87197701
67Endocytosis_Homo sapiens_hsa041440.86408962
68Pathways in cancer_Homo sapiens_hsa052000.85555677
69Wnt signaling pathway_Homo sapiens_hsa043100.82971518
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.81955579
71Insulin signaling pathway_Homo sapiens_hsa049100.81801950
72Shigellosis_Homo sapiens_hsa051310.81363232
73Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81244653
74Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80575579
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.80099036
76Oxytocin signaling pathway_Homo sapiens_hsa049210.78590969
77Prostate cancer_Homo sapiens_hsa052150.78451416
78HIF-1 signaling pathway_Homo sapiens_hsa040660.77725449
79Protein digestion and absorption_Homo sapiens_hsa049740.76824286
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76297633
81Osteoclast differentiation_Homo sapiens_hsa043800.75858474
82Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.75670834
83Platelet activation_Homo sapiens_hsa046110.75166124
84Gastric acid secretion_Homo sapiens_hsa049710.74565547
85Long-term potentiation_Homo sapiens_hsa047200.74433242
86HTLV-I infection_Homo sapiens_hsa051660.74293602
87PI3K-Akt signaling pathway_Homo sapiens_hsa041510.73626375
88Tuberculosis_Homo sapiens_hsa051520.73475814
89Galactose metabolism_Homo sapiens_hsa000520.72790952
90Insulin resistance_Homo sapiens_hsa049310.71752038
91Phagosome_Homo sapiens_hsa041450.71619336
92Apoptosis_Homo sapiens_hsa042100.71268946
93TNF signaling pathway_Homo sapiens_hsa046680.70458907
94Lysine degradation_Homo sapiens_hsa003100.70403009
95Prolactin signaling pathway_Homo sapiens_hsa049170.70135450
96Acute myeloid leukemia_Homo sapiens_hsa052210.70135049
97Choline metabolism in cancer_Homo sapiens_hsa052310.67885941
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.67014337
99Inositol phosphate metabolism_Homo sapiens_hsa005620.65802329
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.65727470
101AMPK signaling pathway_Homo sapiens_hsa041520.65307395
102Cocaine addiction_Homo sapiens_hsa050300.65217139
103MAPK signaling pathway_Homo sapiens_hsa040100.64961639
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63253830
105Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63242364
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63074625
107Oocyte meiosis_Homo sapiens_hsa041140.62841531
108Cholinergic synapse_Homo sapiens_hsa047250.61279684
109Salivary secretion_Homo sapiens_hsa049700.61030229
110N-Glycan biosynthesis_Homo sapiens_hsa005100.59081300
111Ras signaling pathway_Homo sapiens_hsa040140.57018284
112Thyroid hormone synthesis_Homo sapiens_hsa049180.57003453
113Fructose and mannose metabolism_Homo sapiens_hsa000510.50403698
114Glucagon signaling pathway_Homo sapiens_hsa049220.48246555
115Adipocytokine signaling pathway_Homo sapiens_hsa049200.47211040
116Biosynthesis of amino acids_Homo sapiens_hsa012300.46309447
117Pentose phosphate pathway_Homo sapiens_hsa000300.45947333

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