Rank | Gene Set | Z-score |
---|---|---|
1 | postsynaptic membrane organization (GO:0001941) | 6.01775075 |
2 | presynaptic membrane assembly (GO:0097105) | 5.89910963 |
3 | presynaptic membrane organization (GO:0097090) | 5.58819597 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.41508132 |
5 | neuron cell-cell adhesion (GO:0007158) | 5.19933564 |
6 | protein localization to synapse (GO:0035418) | 5.14524657 |
7 | neuronal action potential propagation (GO:0019227) | 5.12357070 |
8 | vocalization behavior (GO:0071625) | 5.11171234 |
9 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 5.10804739 |
10 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.09199918 |
11 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.03866844 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.69573699 |
13 | glutamate receptor signaling pathway (GO:0007215) | 4.54039704 |
14 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.50625310 |
15 | synaptic transmission, glutamatergic (GO:0035249) | 4.28146101 |
16 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.12627779 |
17 | nucleobase catabolic process (GO:0046113) | 3.99608209 |
18 | positive regulation of dendritic spine development (GO:0060999) | 3.98870951 |
19 | positive regulation of membrane potential (GO:0045838) | 3.97305707 |
20 | exploration behavior (GO:0035640) | 3.96579118 |
21 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.94937793 |
22 | synaptic vesicle exocytosis (GO:0016079) | 3.93531070 |
23 | locomotory exploration behavior (GO:0035641) | 3.92867411 |
24 | synaptic vesicle maturation (GO:0016188) | 3.88112735 |
25 | cardiac ventricle formation (GO:0003211) | 3.79856661 |
26 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.78859217 |
27 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.74514276 |
28 | cardiac chamber formation (GO:0003207) | 3.73861456 |
29 | neuron-neuron synaptic transmission (GO:0007270) | 3.70577901 |
30 | regulation of synapse structural plasticity (GO:0051823) | 3.60909878 |
31 | dendritic spine morphogenesis (GO:0060997) | 3.60016561 |
32 | long-term memory (GO:0007616) | 3.57984242 |
33 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.57590121 |
34 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.54977081 |
35 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.52548780 |
36 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.52546991 |
37 | glutamate secretion (GO:0014047) | 3.50858076 |
38 | regulation of pigment cell differentiation (GO:0050932) | 3.50098831 |
39 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.50001783 |
40 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.49912196 |
41 | regulation of postsynaptic membrane potential (GO:0060078) | 3.49785477 |
42 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.47378795 |
43 | regulation of synaptic vesicle transport (GO:1902803) | 3.45006247 |
44 | neuron recognition (GO:0008038) | 3.43172183 |
45 | peptidyl-threonine dephosphorylation (GO:0035970) | 3.36419756 |
46 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.34516080 |
47 | cerebellar granule cell differentiation (GO:0021707) | 3.32729702 |
48 | positive regulation of synapse assembly (GO:0051965) | 3.30627794 |
49 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.27631586 |
50 | behavioral fear response (GO:0001662) | 3.23570433 |
51 | behavioral defense response (GO:0002209) | 3.23570433 |
52 | regulation of respiratory system process (GO:0044065) | 3.22193238 |
53 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.20613813 |
54 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.20401547 |
55 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.18977301 |
56 | membrane assembly (GO:0071709) | 3.15126048 |
57 | generation of neurons (GO:0048699) | 3.13951799 |
58 | righting reflex (GO:0060013) | 3.12501014 |
59 | fear response (GO:0042596) | 3.11018056 |
60 | establishment of mitochondrion localization (GO:0051654) | 3.07609144 |
61 | positive regulation of neurotransmitter transport (GO:0051590) | 3.06631017 |
62 | cell communication by electrical coupling (GO:0010644) | 3.06504782 |
63 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.05939869 |
64 | membrane depolarization (GO:0051899) | 3.03919745 |
65 | regulation of synapse assembly (GO:0051963) | 3.03284880 |
66 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.02308291 |
67 | regulation of respiratory gaseous exchange (GO:0043576) | 3.02243242 |
68 | transmission of nerve impulse (GO:0019226) | 3.01444329 |
69 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.98327851 |
70 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.98254629 |
71 | auditory behavior (GO:0031223) | 2.97991611 |
72 | axonal fasciculation (GO:0007413) | 2.96177340 |
73 | protein localization to cilium (GO:0061512) | 2.95907426 |
74 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.95598506 |
75 | axon extension (GO:0048675) | 2.95257515 |
76 | regulation of synapse maturation (GO:0090128) | 2.94484053 |
77 | learning (GO:0007612) | 2.93477812 |
78 | startle response (GO:0001964) | 2.93467402 |
79 | response to auditory stimulus (GO:0010996) | 2.92636342 |
80 | regulation of dendritic spine development (GO:0060998) | 2.91974474 |
81 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.90053548 |
82 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.88495680 |
83 | neurotransmitter secretion (GO:0007269) | 2.87807898 |
84 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.87198169 |
85 | synapse assembly (GO:0007416) | 2.86029666 |
86 | cell communication involved in cardiac conduction (GO:0086065) | 2.86000500 |
87 | neuronal ion channel clustering (GO:0045161) | 2.84344651 |
88 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.84301688 |
89 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 2.83995802 |
90 | activation of protein kinase A activity (GO:0034199) | 2.83992662 |
91 | regulation of synapse organization (GO:0050807) | 2.83906809 |
92 | dendrite morphogenesis (GO:0048813) | 2.83080622 |
93 | regulation of neurotransmitter secretion (GO:0046928) | 2.82293199 |
94 | membrane depolarization during action potential (GO:0086010) | 2.81677270 |
95 | mannosylation (GO:0097502) | 2.81504119 |
96 | * central nervous system projection neuron axonogenesis (GO:0021952) | 2.81455951 |
97 | * central nervous system neuron axonogenesis (GO:0021955) | 2.80809367 |
98 | mechanosensory behavior (GO:0007638) | 2.80512575 |
99 | gamma-aminobutyric acid transport (GO:0015812) | 2.79652909 |
100 | lymphoid progenitor cell differentiation (GO:0002320) | 2.76428501 |
101 | mitochondrion transport along microtubule (GO:0047497) | 2.76002426 |
102 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.76002426 |
103 | positive regulation of synapse maturation (GO:0090129) | 2.75457335 |
104 | positive regulation of dendrite development (GO:1900006) | 2.73243087 |
105 | respiratory chain complex IV assembly (GO:0008535) | 2.72702101 |
106 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.72356659 |
107 | negative regulation of dendrite development (GO:2000171) | 2.71763440 |
108 | regulation of vesicle fusion (GO:0031338) | 2.71626516 |
109 | regulation of synaptic plasticity (GO:0048167) | 2.69425759 |
110 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.68502136 |
111 | regulation of dendrite morphogenesis (GO:0048814) | 2.67658224 |
112 | memory (GO:0007613) | 2.67481207 |
113 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.66060337 |
114 | peripheral nervous system axon ensheathment (GO:0032292) | 2.65652000 |
115 | myelination in peripheral nervous system (GO:0022011) | 2.65652000 |
116 | layer formation in cerebral cortex (GO:0021819) | 2.65633375 |
117 | nerve growth factor signaling pathway (GO:0038180) | 2.64762240 |
118 | sodium ion export (GO:0071436) | 2.64163892 |
119 | response to histamine (GO:0034776) | 2.62718252 |
120 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.62540068 |
121 | dendritic spine organization (GO:0097061) | 2.62340889 |
122 | cell migration in hindbrain (GO:0021535) | 2.61957262 |
123 | associative learning (GO:0008306) | 2.61385227 |
124 | proline transport (GO:0015824) | 2.61114250 |
125 | neurotransmitter transport (GO:0006836) | 2.60788511 |
126 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.60553886 |
127 | regulation of neurotransmitter transport (GO:0051588) | 2.59686636 |
128 | dendrite development (GO:0016358) | 2.58612374 |
129 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.58162127 |
130 | neuron projection extension (GO:1990138) | 2.58136598 |
131 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.57700789 |
132 | regulation of dendrite development (GO:0050773) | 2.55231879 |
133 | atrial cardiac muscle cell action potential (GO:0086014) | 2.52003911 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * EZH2_22144423_ChIP-Seq_EOC_Human | 7.29402995 |
2 | * GBX2_23144817_ChIP-Seq_PC3_Human | 3.91727728 |
3 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.49834716 |
4 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.07101370 |
5 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.83246069 |
6 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.76979028 |
7 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.74867520 |
8 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.64211856 |
9 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.64211856 |
10 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.58993313 |
11 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.58671098 |
12 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.47568504 |
13 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.39535237 |
14 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.34089256 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.33165484 |
16 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.32683316 |
17 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.29783724 |
18 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.29434850 |
19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.29231916 |
20 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.25139444 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.19449839 |
22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.03757970 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.00740589 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.94024665 |
25 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.90956467 |
26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.87853754 |
27 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.81599436 |
28 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.81201403 |
29 | * DROSHA_22980978_ChIP-Seq_HELA_Human | 1.79742905 |
30 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.79615065 |
31 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.74878522 |
32 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.72451731 |
33 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71984420 |
34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.71764900 |
35 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.70480260 |
36 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.68630560 |
37 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.64438487 |
38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.60875003 |
39 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.59885546 |
40 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.59380880 |
41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58573176 |
42 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.54742376 |
43 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.51775660 |
44 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.49542265 |
45 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.49268565 |
46 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.48592478 |
47 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.46419535 |
48 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.42553081 |
49 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39851024 |
50 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.39154985 |
51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38255859 |
52 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.36272602 |
53 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.30772655 |
54 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.29574757 |
55 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27665979 |
56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.27343471 |
57 | * TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25396723 |
58 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.24481709 |
59 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.23377965 |
60 | AR_19668381_ChIP-Seq_PC3_Human | 1.19553927 |
61 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.17616733 |
62 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.16606497 |
63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15909372 |
64 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.15410137 |
65 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.14752675 |
66 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13532736 |
67 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.12408452 |
68 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.11895919 |
69 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.11599567 |
70 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.10819063 |
71 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.10808545 |
72 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.10465649 |
73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.09895415 |
74 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.09764098 |
75 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.08061559 |
76 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.08014081 |
77 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.07333263 |
78 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06457587 |
79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.06356455 |
80 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.05953117 |
81 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05349538 |
82 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.04028818 |
83 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.03481502 |
84 | TP53_16413492_ChIP-PET_HCT116_Human | 1.03181000 |
85 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.02444420 |
86 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.01900683 |
87 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.01871172 |
88 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.01824746 |
89 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.01118563 |
90 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.00144399 |
91 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.99421805 |
92 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.99096055 |
93 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98805003 |
94 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.98557315 |
95 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.98417685 |
96 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.98119603 |
97 | * STAT3_23295773_ChIP-Seq_U87_Human | 0.97967898 |
98 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.96831567 |
99 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.96760514 |
100 | * KDM2B_26808549_Chip-Seq_REH_Human | 0.96529663 |
101 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.96184055 |
102 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.95473340 |
103 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.94766186 |
104 | * MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.94130240 |
105 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91946777 |
106 | JUN_21703547_ChIP-Seq_K562_Human | 0.91592467 |
107 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.91561956 |
108 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.91508166 |
109 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.91434923 |
110 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.90885183 |
111 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.90765481 |
112 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.90433936 |
113 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.89543906 |
114 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.89497749 |
115 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.89283784 |
116 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.88954758 |
117 | EWS_26573619_Chip-Seq_HEK293_Human | 0.88878194 |
118 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87157787 |
119 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.87157787 |
120 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.87070899 |
121 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.85972489 |
122 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85944919 |
123 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.85824753 |
124 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.85785721 |
125 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85626764 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.17213404 |
2 | MP0003880_abnormal_central_pattern | 5.01403797 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.48259165 |
4 | MP0009379_abnormal_foot_pigmentation | 3.44645042 |
5 | MP0001188_hyperpigmentation | 3.40650637 |
6 | MP0004270_analgesia | 3.23811897 |
7 | MP0009745_abnormal_behavioral_response | 2.94250233 |
8 | MP0005409_darkened_coat_color | 2.86451293 |
9 | MP0005423_abnormal_somatic_nervous | 2.85481824 |
10 | MP0001968_abnormal_touch/_nociception | 2.83987130 |
11 | MP0002735_abnormal_chemical_nociception | 2.66664024 |
12 | MP0002063_abnormal_learning/memory/cond | 2.52682894 |
13 | MP0002734_abnormal_mechanical_nocicepti | 2.44404096 |
14 | MP0002064_seizures | 2.41533409 |
15 | MP0006292_abnormal_olfactory_placode | 2.37891693 |
16 | MP0002272_abnormal_nervous_system | 2.31750360 |
17 | MP0002572_abnormal_emotion/affect_behav | 2.30900384 |
18 | MP0005174_abnormal_tail_pigmentation | 2.21533632 |
19 | MP0000015_abnormal_ear_pigmentation | 2.19827617 |
20 | MP0006276_abnormal_autonomic_nervous | 2.18627419 |
21 | MP0001486_abnormal_startle_reflex | 2.10198471 |
22 | MP0009046_muscle_twitch | 2.09637567 |
23 | MP0003879_abnormal_hair_cell | 2.08532997 |
24 | MP0002736_abnormal_nociception_after | 2.01232747 |
25 | MP0001970_abnormal_pain_threshold | 1.99286993 |
26 | MP0002733_abnormal_thermal_nociception | 1.94079109 |
27 | MP0002067_abnormal_sensory_capabilities | 1.90335208 |
28 | MP0000569_abnormal_digit_pigmentation | 1.86862323 |
29 | MP0004130_abnormal_muscle_cell | 1.84603478 |
30 | MP0001501_abnormal_sleep_pattern | 1.83386575 |
31 | MP0008569_lethality_at_weaning | 1.81210397 |
32 | * MP0002184_abnormal_innervation | 1.72542646 |
33 | MP0002822_catalepsy | 1.71617697 |
34 | MP0002557_abnormal_social/conspecific_i | 1.66221956 |
35 | MP0001905_abnormal_dopamine_level | 1.63801187 |
36 | MP0001440_abnormal_grooming_behavior | 1.61714787 |
37 | MP0001984_abnormal_olfaction | 1.61593826 |
38 | MP0003646_muscle_fatigue | 1.53344847 |
39 | MP0005670_abnormal_white_adipose | 1.52977147 |
40 | MP0002638_abnormal_pupillary_reflex | 1.51191042 |
41 | * MP0000778_abnormal_nervous_system | 1.45688274 |
42 | MP0002876_abnormal_thyroid_physiology | 1.44988140 |
43 | MP0001986_abnormal_taste_sensitivity | 1.41891054 |
44 | MP0004142_abnormal_muscle_tone | 1.40843725 |
45 | MP0000534_abnormal_ureter_morphology | 1.39123330 |
46 | MP0005646_abnormal_pituitary_gland | 1.38496998 |
47 | MP0000372_irregular_coat_pigmentation | 1.37796467 |
48 | MP0002102_abnormal_ear_morphology | 1.35554878 |
49 | MP0003136_yellow_coat_color | 1.34986330 |
50 | MP0005645_abnormal_hypothalamus_physiol | 1.33480028 |
51 | MP0004811_abnormal_neuron_physiology | 1.31260527 |
52 | MP0005503_abnormal_tendon_morphology | 1.30405535 |
53 | MP0004084_abnormal_cardiac_muscle | 1.28650525 |
54 | MP0000631_abnormal_neuroendocrine_gland | 1.27907831 |
55 | MP0000681_abnormal_thyroid_gland | 1.25882264 |
56 | MP0000955_abnormal_spinal_cord | 1.25558414 |
57 | MP0005386_behavior/neurological_phenoty | 1.25235856 |
58 | MP0004924_abnormal_behavior | 1.25235856 |
59 | MP0001502_abnormal_circadian_rhythm | 1.25213526 |
60 | MP0002095_abnormal_skin_pigmentation | 1.24321039 |
61 | MP0003137_abnormal_impulse_conducting | 1.23087782 |
62 | * MP0002882_abnormal_neuron_morphology | 1.19243325 |
63 | MP0004858_abnormal_nervous_system | 1.18401504 |
64 | MP0003122_maternal_imprinting | 1.17528794 |
65 | MP0004145_abnormal_muscle_electrophysio | 1.16380238 |
66 | MP0001299_abnormal_eye_distance/ | 1.11381755 |
67 | MP0003690_abnormal_glial_cell | 1.08536799 |
68 | MP0004085_abnormal_heartbeat | 1.08458252 |
69 | MP0002066_abnormal_motor_capabilities/c | 1.07613749 |
70 | MP0001177_atelectasis | 1.06310990 |
71 | MP0001963_abnormal_hearing_physiology | 1.05554467 |
72 | MP0005171_absent_coat_pigmentation | 1.05191779 |
73 | MP0000751_myopathy | 1.04835520 |
74 | MP0006138_congestive_heart_failure | 1.04004301 |
75 | MP0004885_abnormal_endolymph | 0.98864545 |
76 | MP0001529_abnormal_vocalization | 0.98486957 |
77 | MP0010386_abnormal_urinary_bladder | 0.98035562 |
78 | MP0003633_abnormal_nervous_system | 0.97904910 |
79 | MP0009384_cardiac_valve_regurgitation | 0.96628210 |
80 | MP0005187_abnormal_penis_morphology | 0.96207213 |
81 | MP0005075_abnormal_melanosome_morpholog | 0.94551599 |
82 | MP0004147_increased_porphyrin_level | 0.93395721 |
83 | MP0003283_abnormal_digestive_organ | 0.91549697 |
84 | MP0005620_abnormal_muscle_contractility | 0.89966652 |
85 | MP0003938_abnormal_ear_development | 0.88046369 |
86 | MP0005666_abnormal_adipose_tissue | 0.86580935 |
87 | MP0002177_abnormal_outer_ear | 0.86463121 |
88 | * MP0002752_abnormal_somatic_nervous | 0.86283207 |
89 | MP0000026_abnormal_inner_ear | 0.86221384 |
90 | MP0003787_abnormal_imprinting | 0.85944684 |
91 | * MP0002152_abnormal_brain_morphology | 0.84624374 |
92 | MP0003634_abnormal_glial_cell | 0.84359415 |
93 | * MP0002751_abnormal_autonomic_nervous | 0.83709816 |
94 | MP0004742_abnormal_vestibular_system | 0.83639910 |
95 | MP0000049_abnormal_middle_ear | 0.83569784 |
96 | MP0008438_abnormal_cutaneous_collagen | 0.82233827 |
97 | MP0001879_abnormal_lymphatic_vessel | 0.81659685 |
98 | MP0002909_abnormal_adrenal_gland | 0.81597177 |
99 | MP0002229_neurodegeneration | 0.81481452 |
100 | MP0001485_abnormal_pinna_reflex | 0.80897548 |
101 | MP0005394_taste/olfaction_phenotype | 0.79802090 |
102 | MP0005499_abnormal_olfactory_system | 0.79802090 |
103 | * MP0003861_abnormal_nervous_system | 0.79642976 |
104 | MP0003942_abnormal_urinary_system | 0.78958198 |
105 | MP0000920_abnormal_myelination | 0.78259835 |
106 | MP0009780_abnormal_chondrocyte_physiolo | 0.77724123 |
107 | MP0004036_abnormal_muscle_relaxation | 0.76806544 |
108 | MP0001664_abnormal_digestion | 0.76141501 |
109 | MP0002972_abnormal_cardiac_muscle | 0.75781091 |
110 | MP0003632_abnormal_nervous_system | 0.75676868 |
111 | MP0008260_abnormal_autophagy | 0.73704683 |
112 | MP0003329_amyloid_beta_deposits | 0.71919019 |
113 | MP0010368_abnormal_lymphatic_system | 0.71647909 |
114 | MP0003385_abnormal_body_wall | 0.71453170 |
115 | MP0008874_decreased_physiological_sensi | 0.71353852 |
116 | MP0003631_nervous_system_phenotype | 0.70363147 |
117 | MP0002108_abnormal_muscle_morphology | 0.66179972 |
118 | MP0002082_postnatal_lethality | 0.66005091 |
119 | MP0010770_preweaning_lethality | 0.66005091 |
120 | MP0002081_perinatal_lethality | 0.65982797 |
121 | MP0002971_abnormal_brown_adipose | 0.65870976 |
122 | MP0005551_abnormal_eye_electrophysiolog | 0.65574225 |
123 | MP0010769_abnormal_survival | 0.65482292 |
124 | MP0008775_abnormal_heart_ventricle | 0.65262081 |
125 | MP0002837_dystrophic_cardiac_calcinosis | 0.65136316 |
126 | MP0001348_abnormal_lacrimal_gland | 0.64472690 |
127 | MP0008872_abnormal_physiological_respon | 0.63899945 |
128 | MP0003303_peritoneal_inflammation | 0.60925562 |
129 | MP0003868_abnormal_feces_composition | 0.59788336 |
130 | MP0004484_altered_response_of | 0.59378805 |
131 | MP0004510_myositis | 0.58240830 |
132 | MP0005595_abnormal_vascular_smooth | 0.56997147 |
133 | MP0004381_abnormal_hair_follicle | 0.55956477 |
134 | MP0002069_abnormal_eating/drinking_beha | 0.54483446 |
135 | MP0004215_abnormal_myocardial_fiber | 0.53278910 |
136 | MP0008995_early_reproductive_senescence | 0.52986126 |
137 | MP0000678_abnormal_parathyroid_gland | 0.50825657 |
138 | MP0008789_abnormal_olfactory_epithelium | 0.50015066 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.42554459 |
2 | Hypothermia (HP:0002045) | 5.38588655 |
3 | Myokymia (HP:0002411) | 5.17705009 |
4 | Type I transferrin isoform profile (HP:0003642) | 4.32248288 |
5 | Reduced antithrombin III activity (HP:0001976) | 4.23324358 |
6 | Febrile seizures (HP:0002373) | 4.19202132 |
7 | Focal seizures (HP:0007359) | 4.18917574 |
8 | Thyroid-stimulating hormone excess (HP:0002925) | 4.14352231 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.80253940 |
10 | Epileptic encephalopathy (HP:0200134) | 3.57128909 |
11 | Nonprogressive disorder (HP:0003680) | 3.53064782 |
12 | Visual hallucinations (HP:0002367) | 3.48610135 |
13 | Gaze-evoked nystagmus (HP:0000640) | 3.43511425 |
14 | Broad-based gait (HP:0002136) | 3.40407368 |
15 | Atonic seizures (HP:0010819) | 3.36653486 |
16 | Severe visual impairment (HP:0001141) | 3.23495056 |
17 | Action tremor (HP:0002345) | 3.15098186 |
18 | Retinal dysplasia (HP:0007973) | 3.13427053 |
19 | Mutism (HP:0002300) | 2.88270833 |
20 | Obstructive sleep apnea (HP:0002870) | 2.86531346 |
21 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.80490841 |
22 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.80490841 |
23 | Abnormal protein glycosylation (HP:0012346) | 2.80490841 |
24 | Abnormal glycosylation (HP:0012345) | 2.80490841 |
25 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.77803320 |
26 | Absence seizures (HP:0002121) | 2.75509648 |
27 | Dialeptic seizures (HP:0011146) | 2.75084646 |
28 | Progressive inability to walk (HP:0002505) | 2.73643622 |
29 | Inability to walk (HP:0002540) | 2.71502659 |
30 | Prolonged QT interval (HP:0001657) | 2.71387441 |
31 | Polyphagia (HP:0002591) | 2.69781013 |
32 | Type II lissencephaly (HP:0007260) | 2.58665371 |
33 | Cortical visual impairment (HP:0100704) | 2.58245014 |
34 | Hyperventilation (HP:0002883) | 2.56488602 |
35 | Limb dystonia (HP:0002451) | 2.50081722 |
36 | Scanning speech (HP:0002168) | 2.49242964 |
37 | Syncope (HP:0001279) | 2.48689017 |
38 | Generalized tonic-clonic seizures (HP:0002069) | 2.44714038 |
39 | Epileptiform EEG discharges (HP:0011182) | 2.44614288 |
40 | Bradycardia (HP:0001662) | 2.42428428 |
41 | Amblyopia (HP:0000646) | 2.41984469 |
42 | Absent speech (HP:0001344) | 2.37932241 |
43 | Atrial fibrillation (HP:0005110) | 2.37918343 |
44 | Failure to thrive in infancy (HP:0001531) | 2.37603149 |
45 | Agitation (HP:0000713) | 2.36438747 |
46 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.36231659 |
47 | Primary atrial arrhythmia (HP:0001692) | 2.35779303 |
48 | Hemiparesis (HP:0001269) | 2.35334831 |
49 | Impaired social interactions (HP:0000735) | 2.34843624 |
50 | Abnormal social behavior (HP:0012433) | 2.34843624 |
51 | Anxiety (HP:0000739) | 2.34701442 |
52 | Ankle clonus (HP:0011448) | 2.32778871 |
53 | Depression (HP:0000716) | 2.32082319 |
54 | Megalencephaly (HP:0001355) | 2.31650783 |
55 | Hypoventilation (HP:0002791) | 2.30614361 |
56 | Lower limb amyotrophy (HP:0007210) | 2.30108734 |
57 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.29692565 |
58 | Stereotypic behavior (HP:0000733) | 2.27867953 |
59 | EEG with generalized epileptiform discharges (HP:0011198) | 2.26809141 |
60 | Pheochromocytoma (HP:0002666) | 2.25214287 |
61 | Truncal ataxia (HP:0002078) | 2.24365103 |
62 | Increased hepatocellular lipid droplets (HP:0006565) | 2.24323555 |
63 | Supraventricular tachycardia (HP:0004755) | 2.23495119 |
64 | Spastic gait (HP:0002064) | 2.22320318 |
65 | Supraventricular arrhythmia (HP:0005115) | 2.21362835 |
66 | Abnormal eating behavior (HP:0100738) | 2.21195190 |
67 | Hypsarrhythmia (HP:0002521) | 2.20718778 |
68 | Neurofibrillary tangles (HP:0002185) | 2.20426492 |
69 | Macroglossia (HP:0000158) | 2.19177648 |
70 | Exotropia (HP:0000577) | 2.17532638 |
71 | Urinary urgency (HP:0000012) | 2.16830156 |
72 | Abnormality of the lower motor neuron (HP:0002366) | 2.15915163 |
73 | Abnormal EKG (HP:0003115) | 2.13315640 |
74 | Supranuclear gaze palsy (HP:0000605) | 2.12546181 |
75 | Lower limb muscle weakness (HP:0007340) | 2.11851608 |
76 | Poor eye contact (HP:0000817) | 2.11388697 |
77 | Bundle branch block (HP:0011710) | 2.10293499 |
78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.08401999 |
79 | Genetic anticipation (HP:0003743) | 2.07399004 |
80 | Papilledema (HP:0001085) | 2.06902610 |
81 | Horizontal nystagmus (HP:0000666) | 2.05850783 |
82 | Overgrowth (HP:0001548) | 2.04601735 |
83 | Pachygyria (HP:0001302) | 2.04519899 |
84 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.03967228 |
85 | Renal Fanconi syndrome (HP:0001994) | 2.03966512 |
86 | Dysmetria (HP:0001310) | 2.02694489 |
87 | Fetal akinesia sequence (HP:0001989) | 2.02388145 |
88 | True hermaphroditism (HP:0010459) | 2.02137855 |
89 | Spinal canal stenosis (HP:0003416) | 2.01350791 |
90 | Sleep apnea (HP:0010535) | 2.00861049 |
91 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.00270741 |
92 | Shawl scrotum (HP:0000049) | 1.99314650 |
93 | Pancreatic fibrosis (HP:0100732) | 1.98863416 |
94 | Abnormality of the corticospinal tract (HP:0002492) | 1.98722563 |
95 | Abnormality of magnesium homeostasis (HP:0004921) | 1.97698294 |
96 | Abnormality of the columella (HP:0009929) | 1.96042382 |
97 | Bowel diverticulosis (HP:0005222) | 1.94991828 |
98 | Intellectual disability, severe (HP:0010864) | 1.94731382 |
99 | Hepatocellular necrosis (HP:0001404) | 1.94047227 |
100 | Shallow orbits (HP:0000586) | 1.93729555 |
101 | Excessive salivation (HP:0003781) | 1.93615015 |
102 | Drooling (HP:0002307) | 1.93615015 |
103 | Cutaneous finger syndactyly (HP:0010554) | 1.92974677 |
104 | Abnormal number of erythroid precursors (HP:0012131) | 1.92727559 |
105 | Torticollis (HP:0000473) | 1.91879387 |
106 | Esotropia (HP:0000565) | 1.90421606 |
107 | Protruding tongue (HP:0010808) | 1.90090644 |
108 | Short 4th metacarpal (HP:0010044) | 1.89508325 |
109 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.89508325 |
110 | Turricephaly (HP:0000262) | 1.88873700 |
111 | Lymphangioma (HP:0100764) | 1.88581601 |
112 | Cerebral inclusion bodies (HP:0100314) | 1.88554179 |
113 | Type 2 muscle fiber atrophy (HP:0003554) | 1.87441007 |
114 | Annular pancreas (HP:0001734) | 1.86238101 |
115 | Decreased circulating renin level (HP:0003351) | 1.86127887 |
116 | Sudden death (HP:0001699) | 1.84796293 |
117 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.84081213 |
118 | Iris hypopigmentation (HP:0007730) | 1.83953945 |
119 | Lissencephaly (HP:0001339) | 1.83446428 |
120 | Split foot (HP:0001839) | 1.83093740 |
121 | Abnormality of secondary sexual hair (HP:0009888) | 1.83028661 |
122 | Abnormality of the axillary hair (HP:0100134) | 1.83028661 |
123 | Flat occiput (HP:0005469) | 1.82589619 |
124 | Ocular albinism (HP:0001107) | 1.81261725 |
125 | Absent/shortened dynein arms (HP:0200106) | 1.80788747 |
126 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.80788747 |
127 | Abnormal ciliary motility (HP:0012262) | 1.80620735 |
128 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.80245245 |
129 | Renovascular hypertension (HP:0100817) | 1.77861450 |
130 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.77591262 |
131 | Aplasia of the phalanges of the hand (HP:0009802) | 1.77591262 |
132 | Aplasia involving bones of the extremities (HP:0009825) | 1.77591262 |
133 | Open mouth (HP:0000194) | 1.76791546 |
134 | Hip contracture (HP:0003273) | 1.76533327 |
135 | Tented upper lip vermilion (HP:0010804) | 1.76209720 |
136 | Dysdiadochokinesis (HP:0002075) | 1.75601239 |
137 | Hypoplasia of the corpus callosum (HP:0002079) | 1.75244994 |
138 | Impaired smooth pursuit (HP:0007772) | 1.74903393 |
139 | Neuroendocrine neoplasm (HP:0100634) | 1.74161975 |
140 | Megalocornea (HP:0000485) | 1.72914999 |
141 | Aplastic anemia (HP:0001915) | 1.72494793 |
142 | Attenuation of retinal blood vessels (HP:0007843) | 1.72318380 |
143 | Abnormality of binocular vision (HP:0011514) | 1.70103378 |
144 | Diplopia (HP:0000651) | 1.70103378 |
145 | Limited hip movement (HP:0008800) | 1.67982610 |
146 | Amyotrophic lateral sclerosis (HP:0007354) | 1.66288273 |
147 | Thoracic kyphosis (HP:0002942) | 1.65879893 |
148 | Hemiplegia (HP:0002301) | 1.65852182 |
149 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.65824911 |
150 | Hypoplasia of the brainstem (HP:0002365) | 1.65824911 |
151 | Bradykinesia (HP:0002067) | 1.65824204 |
152 | Abnormality of salivation (HP:0100755) | 1.64371228 |
153 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.64155773 |
154 | Generalized hypopigmentation of hair (HP:0011358) | 1.63472564 |
155 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.63261340 |
156 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.63261340 |
157 | Cutaneous syndactyly (HP:0012725) | 1.60811822 |
158 | Difficulty running (HP:0009046) | 1.60513579 |
159 | Ulnar claw (HP:0001178) | 1.59378938 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TNIK | 7.41995892 |
2 | NTRK3 | 3.98926861 |
3 | MUSK | 3.51035665 |
4 | CASK | 3.21971024 |
5 | MARK1 | 3.12084598 |
6 | MAP2K7 | 3.07078215 |
7 | EPHA4 | 2.54362843 |
8 | CAMKK2 | 2.40989390 |
9 | MAPK13 | 2.26836387 |
10 | FES | 2.21524401 |
11 | MAP3K12 | 2.05815372 |
12 | STK16 | 1.84990716 |
13 | EIF2AK3 | 1.80904560 |
14 | CAMK1 | 1.79989512 |
15 | CDK19 | 1.78408629 |
16 | NLK | 1.73940018 |
17 | MINK1 | 1.70831197 |
18 | MKNK2 | 1.66100555 |
19 | MAP3K9 | 1.66077155 |
20 | PRPF4B | 1.60323988 |
21 | MAP3K4 | 1.60031130 |
22 | RIPK4 | 1.56641017 |
23 | EPHA3 | 1.50716328 |
24 | LATS2 | 1.46418769 |
25 | NTRK2 | 1.38755735 |
26 | CAMKK1 | 1.35739361 |
27 | TYRO3 | 1.34234114 |
28 | DAPK1 | 1.21076402 |
29 | PDGFRA | 1.18469189 |
30 | SGK223 | 1.17930082 |
31 | SGK494 | 1.17930082 |
32 | PRKD3 | 1.14344096 |
33 | SIK2 | 1.12060856 |
34 | GRK7 | 1.11065389 |
35 | CSNK1G2 | 1.06502369 |
36 | DAPK2 | 1.06061496 |
37 | PHKG2 | 1.05059440 |
38 | PHKG1 | 1.05059440 |
39 | ARAF | 1.04690920 |
40 | PKN1 | 1.00814743 |
41 | PAK3 | 0.98046977 |
42 | NTRK1 | 0.97948978 |
43 | DMPK | 0.95846120 |
44 | GRK5 | 0.95832577 |
45 | AKT3 | 0.92650651 |
46 | CDK5 | 0.92493530 |
47 | EPHB2 | 0.91933156 |
48 | MARK2 | 0.91698191 |
49 | MAP2K4 | 0.90265139 |
50 | KIT | 0.89906451 |
51 | CAMK2B | 0.87023670 |
52 | RET | 0.86150903 |
53 | RAF1 | 0.85347104 |
54 | FRK | 0.85089719 |
55 | CAMK1G | 0.84657064 |
56 | CAMK2A | 0.84254398 |
57 | SGK3 | 0.82797312 |
58 | EIF2AK2 | 0.80856486 |
59 | ADRBK2 | 0.78918624 |
60 | MAP3K6 | 0.78787494 |
61 | PTK2 | 0.77759261 |
62 | PRKCG | 0.77195782 |
63 | MATK | 0.76523443 |
64 | WNK3 | 0.76109626 |
65 | CSNK1G3 | 0.74786161 |
66 | CSNK1G1 | 0.72950179 |
67 | CAMK4 | 0.72463806 |
68 | TEC | 0.72434743 |
69 | MKNK1 | 0.71848431 |
70 | KSR1 | 0.69846873 |
71 | DYRK1A | 0.69201856 |
72 | UHMK1 | 0.68598236 |
73 | DDR2 | 0.67130150 |
74 | TAOK2 | 0.65971166 |
75 | ROCK1 | 0.65566490 |
76 | RIPK1 | 0.65534712 |
77 | DYRK2 | 0.65431671 |
78 | MAPKAPK5 | 0.64937945 |
79 | PINK1 | 0.63045623 |
80 | KSR2 | 0.62650573 |
81 | BCR | 0.62589676 |
82 | PAK6 | 0.62046959 |
83 | PRKCZ | 0.61246027 |
84 | PDGFRB | 0.60629400 |
85 | LATS1 | 0.60587525 |
86 | MAPK7 | 0.59201038 |
87 | STK38 | 0.58585714 |
88 | SGK1 | 0.54701083 |
89 | CSNK1A1L | 0.52928509 |
90 | WNK1 | 0.52837974 |
91 | YES1 | 0.52716245 |
92 | MAP3K1 | 0.51615282 |
93 | BMPR2 | 0.51532662 |
94 | SYK | 0.51500799 |
95 | NME2 | 0.51000537 |
96 | OBSCN | 0.50671785 |
97 | CAMK1D | 0.49847831 |
98 | CDK15 | 0.48460315 |
99 | MAP3K7 | 0.48353828 |
100 | RPS6KA3 | 0.48062230 |
101 | PRKCH | 0.47891781 |
102 | MAP3K13 | 0.47464438 |
103 | PNCK | 0.47006221 |
104 | VRK1 | 0.46645928 |
105 | CAMK2D | 0.46253639 |
106 | ERBB2 | 0.46031899 |
107 | MAPK12 | 0.44955210 |
108 | CSNK1D | 0.44269777 |
109 | PLK2 | 0.43750067 |
110 | INSRR | 0.43724360 |
111 | PRKD2 | 0.43579703 |
112 | SGK2 | 0.43257061 |
113 | MAPK4 | 0.42469734 |
114 | MAP2K6 | 0.42156064 |
115 | ROCK2 | 0.41357513 |
116 | TRIB3 | 0.41330007 |
117 | CDK3 | 0.41160855 |
118 | TAOK1 | 0.41102312 |
119 | MAPK10 | 0.39774172 |
120 | CCNB1 | 0.39359526 |
121 | STK11 | 0.38370872 |
122 | PTK2B | 0.37191384 |
123 | PRKCE | 0.36927150 |
124 | FGFR2 | 0.36746316 |
125 | PRKG1 | 0.36449072 |
126 | PRKACA | 0.35858278 |
127 | PIM2 | 0.34963906 |
128 | BMPR1B | 0.33817187 |
129 | TIE1 | 0.33236216 |
130 | NME1 | 0.32523247 |
131 | CAMK2G | 0.31091093 |
132 | BRAF | 0.29785917 |
133 | IRAK2 | 0.28077683 |
134 | CDK11A | 0.27999974 |
135 | RPS6KA2 | 0.27207549 |
136 | MAP3K2 | 0.27146026 |
137 | TLK1 | 0.26605390 |
138 | CDK14 | 0.26274384 |
139 | CLK1 | 0.25805668 |
140 | ADRBK1 | 0.25090599 |
141 | CDK18 | 0.25068616 |
142 | HIPK2 | 0.25064550 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.98914957 |
2 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.94845642 |
3 | Circadian entrainment_Homo sapiens_hsa04713 | 2.75324074 |
4 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.70971282 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.64193162 |
6 | Olfactory transduction_Homo sapiens_hsa04740 | 2.60794751 |
7 | Long-term potentiation_Homo sapiens_hsa04720 | 2.41372540 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 2.30408623 |
9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.26618051 |
10 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.21208197 |
11 | GABAergic synapse_Homo sapiens_hsa04727 | 2.19600639 |
12 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.11475561 |
13 | Taste transduction_Homo sapiens_hsa04742 | 2.02614509 |
14 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.95146960 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.93530424 |
16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.92856532 |
17 | Salivary secretion_Homo sapiens_hsa04970 | 1.92565693 |
18 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.91350534 |
19 | Long-term depression_Homo sapiens_hsa04730 | 1.86288130 |
20 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.77577632 |
21 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.65419319 |
22 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.62532585 |
23 | Insulin secretion_Homo sapiens_hsa04911 | 1.60492047 |
24 | Cocaine addiction_Homo sapiens_hsa05030 | 1.52509895 |
25 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.43483853 |
26 | Renin secretion_Homo sapiens_hsa04924 | 1.41127978 |
27 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.38750832 |
28 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.37090086 |
29 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.37062740 |
30 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.33759068 |
31 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.22949444 |
32 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.21351099 |
33 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.17600712 |
34 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.16727945 |
35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.16625941 |
36 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.15021732 |
37 | Gap junction_Homo sapiens_hsa04540 | 1.14657323 |
38 | Axon guidance_Homo sapiens_hsa04360 | 1.11998198 |
39 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.10679711 |
40 | Phototransduction_Homo sapiens_hsa04744 | 1.09976459 |
41 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.09778447 |
42 | Melanogenesis_Homo sapiens_hsa04916 | 0.99803111 |
43 | Thyroid cancer_Homo sapiens_hsa05216 | 0.99632882 |
44 | Ribosome_Homo sapiens_hsa03010 | 0.94322865 |
45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.93844064 |
46 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.93060783 |
47 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.92628850 |
48 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.83936965 |
49 | Alzheimers disease_Homo sapiens_hsa05010 | 0.83119482 |
50 | Focal adhesion_Homo sapiens_hsa04510 | 0.82182492 |
51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.81959027 |
52 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.80500870 |
53 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.79187896 |
54 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.78586946 |
55 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.78388268 |
56 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.78011245 |
57 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.77447296 |
58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.75786063 |
59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.75595445 |
60 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.73982731 |
61 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.72261767 |
62 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.71869745 |
63 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.71225850 |
64 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.71086686 |
65 | Circadian rhythm_Homo sapiens_hsa04710 | 0.69450686 |
66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68947586 |
67 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.68872582 |
68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.68723687 |
69 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.68471140 |
70 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.68085341 |
71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68028612 |
72 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.67059129 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.66904761 |
74 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.65832714 |
75 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.64991135 |
76 | Alcoholism_Homo sapiens_hsa05034 | 0.64405134 |
77 | Bile secretion_Homo sapiens_hsa04976 | 0.61937540 |
78 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.60041737 |
79 | Glioma_Homo sapiens_hsa05214 | 0.59534899 |
80 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.57800845 |
81 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.57501772 |
82 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.57274853 |
83 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.56886430 |
84 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.56789608 |
85 | Parkinsons disease_Homo sapiens_hsa05012 | 0.56566974 |
86 | Tight junction_Homo sapiens_hsa04530 | 0.55948460 |
87 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55382434 |
88 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55174177 |
89 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.55098046 |
90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.55027704 |
91 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.54712208 |
92 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.53141945 |
93 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52774763 |
94 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.52725666 |
95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.52723886 |
96 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.51894109 |
97 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.51831132 |
98 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51662695 |
99 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.50698328 |
100 | Huntingtons disease_Homo sapiens_hsa05016 | 0.50266578 |
101 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.50128091 |
102 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.47959591 |
103 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46050743 |
104 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.44501036 |
105 | Endometrial cancer_Homo sapiens_hsa05213 | 0.44008545 |
106 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.43790500 |
107 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.43647999 |
108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42576959 |
109 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.42398575 |
110 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.42121455 |
111 | Purine metabolism_Homo sapiens_hsa00230 | 0.41818601 |
112 | Adherens junction_Homo sapiens_hsa04520 | 0.41263947 |
113 | Melanoma_Homo sapiens_hsa05218 | 0.41255420 |
114 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40848496 |
115 | Platelet activation_Homo sapiens_hsa04611 | 0.40651347 |
116 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40066899 |
117 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.39667237 |
118 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.39097571 |
119 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.38008791 |
120 | Protein export_Homo sapiens_hsa03060 | 0.37324717 |
121 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.36006357 |
122 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.35753637 |
123 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.35542862 |
124 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.33705648 |
125 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.32652587 |
126 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.31335647 |
127 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.28947223 |
128 | Other glycan degradation_Homo sapiens_hsa00511 | 0.27859643 |
129 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.27600182 |
130 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.27332018 |
131 | Salmonella infection_Homo sapiens_hsa05132 | 0.27215606 |