PLXNA4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1postsynaptic membrane organization (GO:0001941)6.01775075
2presynaptic membrane assembly (GO:0097105)5.89910963
3presynaptic membrane organization (GO:0097090)5.58819597
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.41508132
5neuron cell-cell adhesion (GO:0007158)5.19933564
6protein localization to synapse (GO:0035418)5.14524657
7neuronal action potential propagation (GO:0019227)5.12357070
8vocalization behavior (GO:0071625)5.11171234
9ionotropic glutamate receptor signaling pathway (GO:0035235)5.10804739
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.09199918
11pyrimidine nucleobase catabolic process (GO:0006208)5.03866844
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.69573699
13glutamate receptor signaling pathway (GO:0007215)4.54039704
14regulation of glutamate receptor signaling pathway (GO:1900449)4.50625310
15synaptic transmission, glutamatergic (GO:0035249)4.28146101
16regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.12627779
17nucleobase catabolic process (GO:0046113)3.99608209
18positive regulation of dendritic spine development (GO:0060999)3.98870951
19positive regulation of membrane potential (GO:0045838)3.97305707
20exploration behavior (GO:0035640)3.96579118
21neurotransmitter-gated ion channel clustering (GO:0072578)3.94937793
22synaptic vesicle exocytosis (GO:0016079)3.93531070
23locomotory exploration behavior (GO:0035641)3.92867411
24synaptic vesicle maturation (GO:0016188)3.88112735
25cardiac ventricle formation (GO:0003211)3.79856661
26positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.78859217
27regulation of excitatory postsynaptic membrane potential (GO:0060079)3.74514276
28cardiac chamber formation (GO:0003207)3.73861456
29neuron-neuron synaptic transmission (GO:0007270)3.70577901
30regulation of synapse structural plasticity (GO:0051823)3.60909878
31dendritic spine morphogenesis (GO:0060997)3.60016561
32long-term memory (GO:0007616)3.57984242
33regulation of synaptic vesicle exocytosis (GO:2000300)3.57590121
34positive regulation of dendritic spine morphogenesis (GO:0061003)3.54977081
35regulation of long-term neuronal synaptic plasticity (GO:0048169)3.52548780
36positive regulation of neurotransmitter secretion (GO:0001956)3.52546991
37glutamate secretion (GO:0014047)3.50858076
38regulation of pigment cell differentiation (GO:0050932)3.50098831
39regulation of neuronal synaptic plasticity (GO:0048168)3.50001783
40regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.49912196
41regulation of postsynaptic membrane potential (GO:0060078)3.49785477
42positive regulation of synaptic transmission, GABAergic (GO:0032230)3.47378795
43regulation of synaptic vesicle transport (GO:1902803)3.45006247
44neuron recognition (GO:0008038)3.43172183
45peptidyl-threonine dephosphorylation (GO:0035970)3.36419756
46G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.34516080
47cerebellar granule cell differentiation (GO:0021707)3.32729702
48positive regulation of synapse assembly (GO:0051965)3.30627794
49cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.27631586
50behavioral fear response (GO:0001662)3.23570433
51behavioral defense response (GO:0002209)3.23570433
52regulation of respiratory system process (GO:0044065)3.22193238
53cerebral cortex radially oriented cell migration (GO:0021799)3.20613813
54regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.20401547
55synaptic vesicle docking involved in exocytosis (GO:0016081)3.18977301
56membrane assembly (GO:0071709)3.15126048
57generation of neurons (GO:0048699)3.13951799
58righting reflex (GO:0060013)3.12501014
59fear response (GO:0042596)3.11018056
60establishment of mitochondrion localization (GO:0051654)3.07609144
61positive regulation of neurotransmitter transport (GO:0051590)3.06631017
62cell communication by electrical coupling (GO:0010644)3.06504782
63membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.05939869
64membrane depolarization (GO:0051899)3.03919745
65regulation of synapse assembly (GO:0051963)3.03284880
66negative regulation of synaptic transmission, GABAergic (GO:0032229)3.02308291
67regulation of respiratory gaseous exchange (GO:0043576)3.02243242
68transmission of nerve impulse (GO:0019226)3.01444329
69positive regulation of dendrite morphogenesis (GO:0050775)2.98327851
70positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.98254629
71auditory behavior (GO:0031223)2.97991611
72axonal fasciculation (GO:0007413)2.96177340
73protein localization to cilium (GO:0061512)2.95907426
74gamma-aminobutyric acid signaling pathway (GO:0007214)2.95598506
75axon extension (GO:0048675)2.95257515
76regulation of synapse maturation (GO:0090128)2.94484053
77learning (GO:0007612)2.93477812
78startle response (GO:0001964)2.93467402
79response to auditory stimulus (GO:0010996)2.92636342
80regulation of dendritic spine development (GO:0060998)2.91974474
81regulation of synaptic transmission, glutamatergic (GO:0051966)2.90053548
82G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.88495680
83neurotransmitter secretion (GO:0007269)2.87807898
84phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.87198169
85synapse assembly (GO:0007416)2.86029666
86cell communication involved in cardiac conduction (GO:0086065)2.86000500
87neuronal ion channel clustering (GO:0045161)2.84344651
88positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.84301688
89regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.83995802
90activation of protein kinase A activity (GO:0034199)2.83992662
91regulation of synapse organization (GO:0050807)2.83906809
92dendrite morphogenesis (GO:0048813)2.83080622
93regulation of neurotransmitter secretion (GO:0046928)2.82293199
94membrane depolarization during action potential (GO:0086010)2.81677270
95mannosylation (GO:0097502)2.81504119
96* central nervous system projection neuron axonogenesis (GO:0021952)2.81455951
97* central nervous system neuron axonogenesis (GO:0021955)2.80809367
98mechanosensory behavior (GO:0007638)2.80512575
99gamma-aminobutyric acid transport (GO:0015812)2.79652909
100lymphoid progenitor cell differentiation (GO:0002320)2.76428501
101mitochondrion transport along microtubule (GO:0047497)2.76002426
102establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.76002426
103positive regulation of synapse maturation (GO:0090129)2.75457335
104positive regulation of dendrite development (GO:1900006)2.73243087
105respiratory chain complex IV assembly (GO:0008535)2.72702101
106regulation of dendritic spine morphogenesis (GO:0061001)2.72356659
107negative regulation of dendrite development (GO:2000171)2.71763440
108regulation of vesicle fusion (GO:0031338)2.71626516
109regulation of synaptic plasticity (GO:0048167)2.69425759
110regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68502136
111regulation of dendrite morphogenesis (GO:0048814)2.67658224
112memory (GO:0007613)2.67481207
113regulation of cardiac muscle cell contraction (GO:0086004)2.66060337
114peripheral nervous system axon ensheathment (GO:0032292)2.65652000
115myelination in peripheral nervous system (GO:0022011)2.65652000
116layer formation in cerebral cortex (GO:0021819)2.65633375
117nerve growth factor signaling pathway (GO:0038180)2.64762240
118sodium ion export (GO:0071436)2.64163892
119response to histamine (GO:0034776)2.62718252
120regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.62540068
121dendritic spine organization (GO:0097061)2.62340889
122cell migration in hindbrain (GO:0021535)2.61957262
123associative learning (GO:0008306)2.61385227
124proline transport (GO:0015824)2.61114250
125neurotransmitter transport (GO:0006836)2.60788511
126regulation of cAMP-dependent protein kinase activity (GO:2000479)2.60553886
127regulation of neurotransmitter transport (GO:0051588)2.59686636
128dendrite development (GO:0016358)2.58612374
129regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.58162127
130neuron projection extension (GO:1990138)2.58136598
131neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.57700789
132regulation of dendrite development (GO:0050773)2.55231879
133atrial cardiac muscle cell action potential (GO:0086014)2.52003911

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* EZH2_22144423_ChIP-Seq_EOC_Human7.29402995
2* GBX2_23144817_ChIP-Seq_PC3_Human3.91727728
3* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.49834716
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.07101370
5* EZH2_27304074_Chip-Seq_ESCs_Mouse2.83246069
6* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.76979028
7* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.74867520
8* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64211856
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64211856
10* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58993313
11* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58671098
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.47568504
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.39535237
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.34089256
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.33165484
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.32683316
17* EED_16625203_ChIP-ChIP_MESCs_Mouse2.29783724
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29434850
19IGF1R_20145208_ChIP-Seq_DFB_Human2.29231916
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.25139444
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.19449839
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.03757970
23TAF15_26573619_Chip-Seq_HEK293_Human2.00740589
24IKZF1_21737484_ChIP-ChIP_HCT116_Human1.94024665
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.90956467
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.87853754
27* REST_18959480_ChIP-ChIP_MESCs_Mouse1.81599436
28* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.81201403
29* DROSHA_22980978_ChIP-Seq_HELA_Human1.79742905
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79615065
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.74878522
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.72451731
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71984420
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.71764900
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.70480260
36RBPJ_22232070_ChIP-Seq_NCS_Mouse1.68630560
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64438487
38P300_19829295_ChIP-Seq_ESCs_Human1.60875003
39* SMAD4_21799915_ChIP-Seq_A2780_Human1.59885546
40SMAD_19615063_ChIP-ChIP_OVARY_Human1.59380880
41ZNF274_21170338_ChIP-Seq_K562_Hela1.58573176
42RARB_27405468_Chip-Seq_BRAIN_Mouse1.54742376
43* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51775660
44RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.49542265
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.49268565
46AR_21572438_ChIP-Seq_LNCaP_Human1.48592478
47RNF2_27304074_Chip-Seq_NSC_Mouse1.46419535
48EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42553081
49FUS_26573619_Chip-Seq_HEK293_Human1.39851024
50EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.39154985
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38255859
52* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36272602
53* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.30772655
54EP300_21415370_ChIP-Seq_HL-1_Mouse1.29574757
55CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27665979
56AR_25329375_ChIP-Seq_VCAP_Human1.27343471
57* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25396723
58ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.24481709
59* SMAD3_21741376_ChIP-Seq_EPCs_Human1.23377965
60AR_19668381_ChIP-Seq_PC3_Human1.19553927
61* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17616733
62* RING1B_27294783_Chip-Seq_ESCs_Mouse1.16606497
63LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.15909372
64GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15410137
65SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14752675
66* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13532736
67TRIM28_21343339_ChIP-Seq_HEK293_Human1.12408452
68NANOG_18555785_Chip-Seq_ESCs_Mouse1.11895919
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11599567
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10819063
71RUNX2_22187159_ChIP-Seq_PCA_Human1.10808545
72* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10465649
73TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09895415
74* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.09764098
75* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08061559
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.08014081
77KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.07333263
78LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06457587
79EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06356455
80AHR_22903824_ChIP-Seq_MCF-7_Human1.05953117
81* PRDM14_20953172_ChIP-Seq_ESCs_Human1.05349538
82FLI1_27457419_Chip-Seq_LIVER_Mouse1.04028818
83ARNT_22903824_ChIP-Seq_MCF-7_Human1.03481502
84TP53_16413492_ChIP-PET_HCT116_Human1.03181000
85ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.02444420
86* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01900683
87* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01871172
88HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01824746
89ISL1_27105846_Chip-Seq_CPCs_Mouse1.01118563
90SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.00144399
91* RING1B_27294783_Chip-Seq_NPCs_Mouse0.99421805
92ERG_21242973_ChIP-ChIP_JURKAT_Human0.99096055
93P53_22387025_ChIP-Seq_ESCs_Mouse0.98805003
94SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98557315
95* SMAD4_21741376_ChIP-Seq_HESCs_Human0.98417685
96E2F1_18555785_Chip-Seq_ESCs_Mouse0.98119603
97* STAT3_23295773_ChIP-Seq_U87_Human0.97967898
98NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96831567
99SOX9_26525672_Chip-Seq_HEART_Mouse0.96760514
100* KDM2B_26808549_Chip-Seq_REH_Human0.96529663
101TP53_18474530_ChIP-ChIP_U2OS_Human0.96184055
102* TCF4_23295773_ChIP-Seq_U87_Human0.95473340
103CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94766186
104* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94130240
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91946777
106JUN_21703547_ChIP-Seq_K562_Human0.91592467
107SOX2_21211035_ChIP-Seq_LN229_Gbm0.91561956
108CMYC_18555785_Chip-Seq_ESCs_Mouse0.91508166
109YAP1_20516196_ChIP-Seq_MESCs_Mouse0.91434923
110NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90885183
111CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.90765481
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90433936
113TAL1_26923725_Chip-Seq_HPCs_Mouse0.89543906
114ER_23166858_ChIP-Seq_MCF-7_Human0.89497749
115UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89283784
116SUZ12_18555785_Chip-Seq_ESCs_Mouse0.88954758
117EWS_26573619_Chip-Seq_HEK293_Human0.88878194
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87157787
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87157787
120EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.87070899
121SCL_19346495_ChIP-Seq_HPC-7_Human0.85972489
122BCAT_22108803_ChIP-Seq_LS180_Human0.85944919
123RUNX1_27457419_Chip-Seq_LIVER_Mouse0.85824753
124* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.85785721
125SUZ12_27294783_Chip-Seq_NPCs_Mouse0.85626764

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.17213404
2MP0003880_abnormal_central_pattern5.01403797
3MP0003635_abnormal_synaptic_transmissio3.48259165
4MP0009379_abnormal_foot_pigmentation3.44645042
5MP0001188_hyperpigmentation3.40650637
6MP0004270_analgesia3.23811897
7MP0009745_abnormal_behavioral_response2.94250233
8MP0005409_darkened_coat_color2.86451293
9MP0005423_abnormal_somatic_nervous2.85481824
10MP0001968_abnormal_touch/_nociception2.83987130
11MP0002735_abnormal_chemical_nociception2.66664024
12MP0002063_abnormal_learning/memory/cond2.52682894
13MP0002734_abnormal_mechanical_nocicepti2.44404096
14MP0002064_seizures2.41533409
15MP0006292_abnormal_olfactory_placode2.37891693
16MP0002272_abnormal_nervous_system2.31750360
17MP0002572_abnormal_emotion/affect_behav2.30900384
18MP0005174_abnormal_tail_pigmentation2.21533632
19MP0000015_abnormal_ear_pigmentation2.19827617
20MP0006276_abnormal_autonomic_nervous2.18627419
21MP0001486_abnormal_startle_reflex2.10198471
22MP0009046_muscle_twitch2.09637567
23MP0003879_abnormal_hair_cell2.08532997
24MP0002736_abnormal_nociception_after2.01232747
25MP0001970_abnormal_pain_threshold1.99286993
26MP0002733_abnormal_thermal_nociception1.94079109
27MP0002067_abnormal_sensory_capabilities1.90335208
28MP0000569_abnormal_digit_pigmentation1.86862323
29MP0004130_abnormal_muscle_cell1.84603478
30MP0001501_abnormal_sleep_pattern1.83386575
31MP0008569_lethality_at_weaning1.81210397
32* MP0002184_abnormal_innervation1.72542646
33MP0002822_catalepsy1.71617697
34MP0002557_abnormal_social/conspecific_i1.66221956
35MP0001905_abnormal_dopamine_level1.63801187
36MP0001440_abnormal_grooming_behavior1.61714787
37MP0001984_abnormal_olfaction1.61593826
38MP0003646_muscle_fatigue1.53344847
39MP0005670_abnormal_white_adipose1.52977147
40MP0002638_abnormal_pupillary_reflex1.51191042
41* MP0000778_abnormal_nervous_system1.45688274
42MP0002876_abnormal_thyroid_physiology1.44988140
43MP0001986_abnormal_taste_sensitivity1.41891054
44MP0004142_abnormal_muscle_tone1.40843725
45MP0000534_abnormal_ureter_morphology1.39123330
46MP0005646_abnormal_pituitary_gland1.38496998
47MP0000372_irregular_coat_pigmentation1.37796467
48MP0002102_abnormal_ear_morphology1.35554878
49MP0003136_yellow_coat_color1.34986330
50MP0005645_abnormal_hypothalamus_physiol1.33480028
51MP0004811_abnormal_neuron_physiology1.31260527
52MP0005503_abnormal_tendon_morphology1.30405535
53MP0004084_abnormal_cardiac_muscle1.28650525
54MP0000631_abnormal_neuroendocrine_gland1.27907831
55MP0000681_abnormal_thyroid_gland1.25882264
56MP0000955_abnormal_spinal_cord1.25558414
57MP0005386_behavior/neurological_phenoty1.25235856
58MP0004924_abnormal_behavior1.25235856
59MP0001502_abnormal_circadian_rhythm1.25213526
60MP0002095_abnormal_skin_pigmentation1.24321039
61MP0003137_abnormal_impulse_conducting1.23087782
62* MP0002882_abnormal_neuron_morphology1.19243325
63MP0004858_abnormal_nervous_system1.18401504
64MP0003122_maternal_imprinting1.17528794
65MP0004145_abnormal_muscle_electrophysio1.16380238
66MP0001299_abnormal_eye_distance/1.11381755
67MP0003690_abnormal_glial_cell1.08536799
68MP0004085_abnormal_heartbeat1.08458252
69MP0002066_abnormal_motor_capabilities/c1.07613749
70MP0001177_atelectasis1.06310990
71MP0001963_abnormal_hearing_physiology1.05554467
72MP0005171_absent_coat_pigmentation1.05191779
73MP0000751_myopathy1.04835520
74MP0006138_congestive_heart_failure1.04004301
75MP0004885_abnormal_endolymph0.98864545
76MP0001529_abnormal_vocalization0.98486957
77MP0010386_abnormal_urinary_bladder0.98035562
78MP0003633_abnormal_nervous_system0.97904910
79MP0009384_cardiac_valve_regurgitation0.96628210
80MP0005187_abnormal_penis_morphology0.96207213
81MP0005075_abnormal_melanosome_morpholog0.94551599
82MP0004147_increased_porphyrin_level0.93395721
83MP0003283_abnormal_digestive_organ0.91549697
84MP0005620_abnormal_muscle_contractility0.89966652
85MP0003938_abnormal_ear_development0.88046369
86MP0005666_abnormal_adipose_tissue0.86580935
87MP0002177_abnormal_outer_ear0.86463121
88* MP0002752_abnormal_somatic_nervous0.86283207
89MP0000026_abnormal_inner_ear0.86221384
90MP0003787_abnormal_imprinting0.85944684
91* MP0002152_abnormal_brain_morphology0.84624374
92MP0003634_abnormal_glial_cell0.84359415
93* MP0002751_abnormal_autonomic_nervous0.83709816
94MP0004742_abnormal_vestibular_system0.83639910
95MP0000049_abnormal_middle_ear0.83569784
96MP0008438_abnormal_cutaneous_collagen0.82233827
97MP0001879_abnormal_lymphatic_vessel0.81659685
98MP0002909_abnormal_adrenal_gland0.81597177
99MP0002229_neurodegeneration0.81481452
100MP0001485_abnormal_pinna_reflex0.80897548
101MP0005394_taste/olfaction_phenotype0.79802090
102MP0005499_abnormal_olfactory_system0.79802090
103* MP0003861_abnormal_nervous_system0.79642976
104MP0003942_abnormal_urinary_system0.78958198
105MP0000920_abnormal_myelination0.78259835
106MP0009780_abnormal_chondrocyte_physiolo0.77724123
107MP0004036_abnormal_muscle_relaxation0.76806544
108MP0001664_abnormal_digestion0.76141501
109MP0002972_abnormal_cardiac_muscle0.75781091
110MP0003632_abnormal_nervous_system0.75676868
111MP0008260_abnormal_autophagy0.73704683
112MP0003329_amyloid_beta_deposits0.71919019
113MP0010368_abnormal_lymphatic_system0.71647909
114MP0003385_abnormal_body_wall0.71453170
115MP0008874_decreased_physiological_sensi0.71353852
116MP0003631_nervous_system_phenotype0.70363147
117MP0002108_abnormal_muscle_morphology0.66179972
118MP0002082_postnatal_lethality0.66005091
119MP0010770_preweaning_lethality0.66005091
120MP0002081_perinatal_lethality0.65982797
121MP0002971_abnormal_brown_adipose0.65870976
122MP0005551_abnormal_eye_electrophysiolog0.65574225
123MP0010769_abnormal_survival0.65482292
124MP0008775_abnormal_heart_ventricle0.65262081
125MP0002837_dystrophic_cardiac_calcinosis0.65136316
126MP0001348_abnormal_lacrimal_gland0.64472690
127MP0008872_abnormal_physiological_respon0.63899945
128MP0003303_peritoneal_inflammation0.60925562
129MP0003868_abnormal_feces_composition0.59788336
130MP0004484_altered_response_of0.59378805
131MP0004510_myositis0.58240830
132MP0005595_abnormal_vascular_smooth0.56997147
133MP0004381_abnormal_hair_follicle0.55956477
134MP0002069_abnormal_eating/drinking_beha0.54483446
135MP0004215_abnormal_myocardial_fiber0.53278910
136MP0008995_early_reproductive_senescence0.52986126
137MP0000678_abnormal_parathyroid_gland0.50825657
138MP0008789_abnormal_olfactory_epithelium0.50015066

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.42554459
2Hypothermia (HP:0002045)5.38588655
3Myokymia (HP:0002411)5.17705009
4Type I transferrin isoform profile (HP:0003642)4.32248288
5Reduced antithrombin III activity (HP:0001976)4.23324358
6Febrile seizures (HP:0002373)4.19202132
7Focal seizures (HP:0007359)4.18917574
8Thyroid-stimulating hormone excess (HP:0002925)4.14352231
9Progressive cerebellar ataxia (HP:0002073)3.80253940
10Epileptic encephalopathy (HP:0200134)3.57128909
11Nonprogressive disorder (HP:0003680)3.53064782
12Visual hallucinations (HP:0002367)3.48610135
13Gaze-evoked nystagmus (HP:0000640)3.43511425
14Broad-based gait (HP:0002136)3.40407368
15Atonic seizures (HP:0010819)3.36653486
16Severe visual impairment (HP:0001141)3.23495056
17Action tremor (HP:0002345)3.15098186
18Retinal dysplasia (HP:0007973)3.13427053
19Mutism (HP:0002300)2.88270833
20Obstructive sleep apnea (HP:0002870)2.86531346
21Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.80490841
22Abnormal protein N-linked glycosylation (HP:0012347)2.80490841
23Abnormal protein glycosylation (HP:0012346)2.80490841
24Abnormal glycosylation (HP:0012345)2.80490841
25Absent rod-and cone-mediated responses on ERG (HP:0007688)2.77803320
26Absence seizures (HP:0002121)2.75509648
27Dialeptic seizures (HP:0011146)2.75084646
28Progressive inability to walk (HP:0002505)2.73643622
29Inability to walk (HP:0002540)2.71502659
30Prolonged QT interval (HP:0001657)2.71387441
31Polyphagia (HP:0002591)2.69781013
32Type II lissencephaly (HP:0007260)2.58665371
33Cortical visual impairment (HP:0100704)2.58245014
34Hyperventilation (HP:0002883)2.56488602
35Limb dystonia (HP:0002451)2.50081722
36Scanning speech (HP:0002168)2.49242964
37Syncope (HP:0001279)2.48689017
38Generalized tonic-clonic seizures (HP:0002069)2.44714038
39Epileptiform EEG discharges (HP:0011182)2.44614288
40Bradycardia (HP:0001662)2.42428428
41Amblyopia (HP:0000646)2.41984469
42Absent speech (HP:0001344)2.37932241
43Atrial fibrillation (HP:0005110)2.37918343
44Failure to thrive in infancy (HP:0001531)2.37603149
45Agitation (HP:0000713)2.36438747
46Urinary bladder sphincter dysfunction (HP:0002839)2.36231659
47Primary atrial arrhythmia (HP:0001692)2.35779303
48Hemiparesis (HP:0001269)2.35334831
49Impaired social interactions (HP:0000735)2.34843624
50Abnormal social behavior (HP:0012433)2.34843624
51Anxiety (HP:0000739)2.34701442
52Ankle clonus (HP:0011448)2.32778871
53Depression (HP:0000716)2.32082319
54Megalencephaly (HP:0001355)2.31650783
55Hypoventilation (HP:0002791)2.30614361
56Lower limb amyotrophy (HP:0007210)2.30108734
57Impaired vibration sensation in the lower limbs (HP:0002166)2.29692565
58Stereotypic behavior (HP:0000733)2.27867953
59EEG with generalized epileptiform discharges (HP:0011198)2.26809141
60Pheochromocytoma (HP:0002666)2.25214287
61Truncal ataxia (HP:0002078)2.24365103
62Increased hepatocellular lipid droplets (HP:0006565)2.24323555
63Supraventricular tachycardia (HP:0004755)2.23495119
64Spastic gait (HP:0002064)2.22320318
65Supraventricular arrhythmia (HP:0005115)2.21362835
66Abnormal eating behavior (HP:0100738)2.21195190
67Hypsarrhythmia (HP:0002521)2.20718778
68Neurofibrillary tangles (HP:0002185)2.20426492
69Macroglossia (HP:0000158)2.19177648
70Exotropia (HP:0000577)2.17532638
71Urinary urgency (HP:0000012)2.16830156
72Abnormality of the lower motor neuron (HP:0002366)2.15915163
73Abnormal EKG (HP:0003115)2.13315640
74Supranuclear gaze palsy (HP:0000605)2.12546181
75Lower limb muscle weakness (HP:0007340)2.11851608
76Poor eye contact (HP:0000817)2.11388697
77Bundle branch block (HP:0011710)2.10293499
78Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.08401999
79Genetic anticipation (HP:0003743)2.07399004
80Papilledema (HP:0001085)2.06902610
81Horizontal nystagmus (HP:0000666)2.05850783
82Overgrowth (HP:0001548)2.04601735
83Pachygyria (HP:0001302)2.04519899
84Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.03967228
85Renal Fanconi syndrome (HP:0001994)2.03966512
86Dysmetria (HP:0001310)2.02694489
87Fetal akinesia sequence (HP:0001989)2.02388145
88True hermaphroditism (HP:0010459)2.02137855
89Spinal canal stenosis (HP:0003416)2.01350791
90Sleep apnea (HP:0010535)2.00861049
91Abnormal rod and cone electroretinograms (HP:0008323)2.00270741
92Shawl scrotum (HP:0000049)1.99314650
93Pancreatic fibrosis (HP:0100732)1.98863416
94Abnormality of the corticospinal tract (HP:0002492)1.98722563
95Abnormality of magnesium homeostasis (HP:0004921)1.97698294
96Abnormality of the columella (HP:0009929)1.96042382
97Bowel diverticulosis (HP:0005222)1.94991828
98Intellectual disability, severe (HP:0010864)1.94731382
99Hepatocellular necrosis (HP:0001404)1.94047227
100Shallow orbits (HP:0000586)1.93729555
101Excessive salivation (HP:0003781)1.93615015
102Drooling (HP:0002307)1.93615015
103Cutaneous finger syndactyly (HP:0010554)1.92974677
104Abnormal number of erythroid precursors (HP:0012131)1.92727559
105Torticollis (HP:0000473)1.91879387
106Esotropia (HP:0000565)1.90421606
107Protruding tongue (HP:0010808)1.90090644
108Short 4th metacarpal (HP:0010044)1.89508325
109Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.89508325
110Turricephaly (HP:0000262)1.88873700
111Lymphangioma (HP:0100764)1.88581601
112Cerebral inclusion bodies (HP:0100314)1.88554179
113Type 2 muscle fiber atrophy (HP:0003554)1.87441007
114Annular pancreas (HP:0001734)1.86238101
115Decreased circulating renin level (HP:0003351)1.86127887
116Sudden death (HP:0001699)1.84796293
117Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.84081213
118Iris hypopigmentation (HP:0007730)1.83953945
119Lissencephaly (HP:0001339)1.83446428
120Split foot (HP:0001839)1.83093740
121Abnormality of secondary sexual hair (HP:0009888)1.83028661
122Abnormality of the axillary hair (HP:0100134)1.83028661
123Flat occiput (HP:0005469)1.82589619
124Ocular albinism (HP:0001107)1.81261725
125Absent/shortened dynein arms (HP:0200106)1.80788747
126Dynein arm defect of respiratory motile cilia (HP:0012255)1.80788747
127Abnormal ciliary motility (HP:0012262)1.80620735
128Abnormality of cells of the erythroid lineage (HP:0012130)1.80245245
129Renovascular hypertension (HP:0100817)1.77861450
130Aplasia involving bones of the upper limbs (HP:0009823)1.77591262
131Aplasia of the phalanges of the hand (HP:0009802)1.77591262
132Aplasia involving bones of the extremities (HP:0009825)1.77591262
133Open mouth (HP:0000194)1.76791546
134Hip contracture (HP:0003273)1.76533327
135Tented upper lip vermilion (HP:0010804)1.76209720
136Dysdiadochokinesis (HP:0002075)1.75601239
137Hypoplasia of the corpus callosum (HP:0002079)1.75244994
138Impaired smooth pursuit (HP:0007772)1.74903393
139Neuroendocrine neoplasm (HP:0100634)1.74161975
140Megalocornea (HP:0000485)1.72914999
141Aplastic anemia (HP:0001915)1.72494793
142Attenuation of retinal blood vessels (HP:0007843)1.72318380
143Abnormality of binocular vision (HP:0011514)1.70103378
144Diplopia (HP:0000651)1.70103378
145Limited hip movement (HP:0008800)1.67982610
146Amyotrophic lateral sclerosis (HP:0007354)1.66288273
147Thoracic kyphosis (HP:0002942)1.65879893
148Hemiplegia (HP:0002301)1.65852182
149Aplasia/Hypoplasia of the brainstem (HP:0007362)1.65824911
150Hypoplasia of the brainstem (HP:0002365)1.65824911
151Bradykinesia (HP:0002067)1.65824204
152Abnormality of salivation (HP:0100755)1.64371228
153Abnormality of the heme biosynthetic pathway (HP:0010472)1.64155773
154Generalized hypopigmentation of hair (HP:0011358)1.63472564
155Abnormal respiratory motile cilium morphology (HP:0005938)1.63261340
156Abnormal respiratory epithelium morphology (HP:0012253)1.63261340
157Cutaneous syndactyly (HP:0012725)1.60811822
158Difficulty running (HP:0009046)1.60513579
159Ulnar claw (HP:0001178)1.59378938

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK7.41995892
2NTRK33.98926861
3MUSK3.51035665
4CASK3.21971024
5MARK13.12084598
6MAP2K73.07078215
7EPHA42.54362843
8CAMKK22.40989390
9MAPK132.26836387
10FES2.21524401
11MAP3K122.05815372
12STK161.84990716
13EIF2AK31.80904560
14CAMK11.79989512
15CDK191.78408629
16NLK1.73940018
17MINK11.70831197
18MKNK21.66100555
19MAP3K91.66077155
20PRPF4B1.60323988
21MAP3K41.60031130
22RIPK41.56641017
23EPHA31.50716328
24LATS21.46418769
25NTRK21.38755735
26CAMKK11.35739361
27TYRO31.34234114
28DAPK11.21076402
29PDGFRA1.18469189
30SGK2231.17930082
31SGK4941.17930082
32PRKD31.14344096
33SIK21.12060856
34GRK71.11065389
35CSNK1G21.06502369
36DAPK21.06061496
37PHKG21.05059440
38PHKG11.05059440
39ARAF1.04690920
40PKN11.00814743
41PAK30.98046977
42NTRK10.97948978
43DMPK0.95846120
44GRK50.95832577
45AKT30.92650651
46CDK50.92493530
47EPHB20.91933156
48MARK20.91698191
49MAP2K40.90265139
50KIT0.89906451
51CAMK2B0.87023670
52RET0.86150903
53RAF10.85347104
54FRK0.85089719
55CAMK1G0.84657064
56CAMK2A0.84254398
57SGK30.82797312
58EIF2AK20.80856486
59ADRBK20.78918624
60MAP3K60.78787494
61PTK20.77759261
62PRKCG0.77195782
63MATK0.76523443
64WNK30.76109626
65CSNK1G30.74786161
66CSNK1G10.72950179
67CAMK40.72463806
68TEC0.72434743
69MKNK10.71848431
70KSR10.69846873
71DYRK1A0.69201856
72UHMK10.68598236
73DDR20.67130150
74TAOK20.65971166
75ROCK10.65566490
76RIPK10.65534712
77DYRK20.65431671
78MAPKAPK50.64937945
79PINK10.63045623
80KSR20.62650573
81BCR0.62589676
82PAK60.62046959
83PRKCZ0.61246027
84PDGFRB0.60629400
85LATS10.60587525
86MAPK70.59201038
87STK380.58585714
88SGK10.54701083
89CSNK1A1L0.52928509
90WNK10.52837974
91YES10.52716245
92MAP3K10.51615282
93BMPR20.51532662
94SYK0.51500799
95NME20.51000537
96OBSCN0.50671785
97CAMK1D0.49847831
98CDK150.48460315
99MAP3K70.48353828
100RPS6KA30.48062230
101PRKCH0.47891781
102MAP3K130.47464438
103PNCK0.47006221
104VRK10.46645928
105CAMK2D0.46253639
106ERBB20.46031899
107MAPK120.44955210
108CSNK1D0.44269777
109PLK20.43750067
110INSRR0.43724360
111PRKD20.43579703
112SGK20.43257061
113MAPK40.42469734
114MAP2K60.42156064
115ROCK20.41357513
116TRIB30.41330007
117CDK30.41160855
118TAOK10.41102312
119MAPK100.39774172
120CCNB10.39359526
121STK110.38370872
122PTK2B0.37191384
123PRKCE0.36927150
124FGFR20.36746316
125PRKG10.36449072
126PRKACA0.35858278
127PIM20.34963906
128BMPR1B0.33817187
129TIE10.33236216
130NME10.32523247
131CAMK2G0.31091093
132BRAF0.29785917
133IRAK20.28077683
134CDK11A0.27999974
135RPS6KA20.27207549
136MAP3K20.27146026
137TLK10.26605390
138CDK140.26274384
139CLK10.25805668
140ADRBK10.25090599
141CDK180.25068616
142HIPK20.25064550

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.98914957
2Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.94845642
3Circadian entrainment_Homo sapiens_hsa047132.75324074
4Glutamatergic synapse_Homo sapiens_hsa047242.70971282
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.64193162
6Olfactory transduction_Homo sapiens_hsa047402.60794751
7Long-term potentiation_Homo sapiens_hsa047202.41372540
8Morphine addiction_Homo sapiens_hsa050322.30408623
9Amphetamine addiction_Homo sapiens_hsa050312.26618051
10Synaptic vesicle cycle_Homo sapiens_hsa047212.21208197
11GABAergic synapse_Homo sapiens_hsa047272.19600639
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.11475561
13Taste transduction_Homo sapiens_hsa047422.02614509
14Aldosterone synthesis and secretion_Homo sapiens_hsa049251.95146960
15Cholinergic synapse_Homo sapiens_hsa047251.93530424
16Dopaminergic synapse_Homo sapiens_hsa047281.92856532
17Salivary secretion_Homo sapiens_hsa049701.92565693
18Serotonergic synapse_Homo sapiens_hsa047261.91350534
19Long-term depression_Homo sapiens_hsa047301.86288130
20Calcium signaling pathway_Homo sapiens_hsa040201.77577632
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.65419319
22Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.62532585
23Insulin secretion_Homo sapiens_hsa049111.60492047
24Cocaine addiction_Homo sapiens_hsa050301.52509895
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.43483853
26Renin secretion_Homo sapiens_hsa049241.41127978
27Oxytocin signaling pathway_Homo sapiens_hsa049211.38750832
28Gastric acid secretion_Homo sapiens_hsa049711.37090086
29GnRH signaling pathway_Homo sapiens_hsa049121.37062740
30cAMP signaling pathway_Homo sapiens_hsa040241.33759068
31Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.22949444
32Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.21351099
33Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.17600712
34N-Glycan biosynthesis_Homo sapiens_hsa005101.16727945
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.16625941
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.15021732
37Gap junction_Homo sapiens_hsa045401.14657323
38Axon guidance_Homo sapiens_hsa043601.11998198
39Dorso-ventral axis formation_Homo sapiens_hsa043201.10679711
40Phototransduction_Homo sapiens_hsa047441.09976459
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09778447
42Melanogenesis_Homo sapiens_hsa049160.99803111
43Thyroid cancer_Homo sapiens_hsa052160.99632882
44Ribosome_Homo sapiens_hsa030100.94322865
45Cardiac muscle contraction_Homo sapiens_hsa042600.93844064
46ECM-receptor interaction_Homo sapiens_hsa045120.93060783
47Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92628850
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83936965
49Alzheimers disease_Homo sapiens_hsa050100.83119482
50Focal adhesion_Homo sapiens_hsa045100.82182492
51SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81959027
52Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80500870
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79187896
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.78586946
55AMPK signaling pathway_Homo sapiens_hsa041520.78388268
56Longevity regulating pathway - mammal_Homo sapiens_hsa042110.78011245
57Oxidative phosphorylation_Homo sapiens_hsa001900.77447296
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75786063
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75595445
60Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73982731
61ErbB signaling pathway_Homo sapiens_hsa040120.72261767
62Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.71869745
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71225850
64African trypanosomiasis_Homo sapiens_hsa051430.71086686
65Circadian rhythm_Homo sapiens_hsa047100.69450686
66Fatty acid biosynthesis_Homo sapiens_hsa000610.68947586
67Estrogen signaling pathway_Homo sapiens_hsa049150.68872582
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.68723687
69PPAR signaling pathway_Homo sapiens_hsa033200.68471140
70Wnt signaling pathway_Homo sapiens_hsa043100.68085341
71Collecting duct acid secretion_Homo sapiens_hsa049660.68028612
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67059129
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.66904761
74Hippo signaling pathway_Homo sapiens_hsa043900.65832714
75Pancreatic secretion_Homo sapiens_hsa049720.64991135
76Alcoholism_Homo sapiens_hsa050340.64405134
77Bile secretion_Homo sapiens_hsa049760.61937540
78Insulin signaling pathway_Homo sapiens_hsa049100.60041737
79Glioma_Homo sapiens_hsa052140.59534899
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.57800845
81AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57501772
82Glucagon signaling pathway_Homo sapiens_hsa049220.57274853
83Prolactin signaling pathway_Homo sapiens_hsa049170.56886430
84Thyroid hormone synthesis_Homo sapiens_hsa049180.56789608
85Parkinsons disease_Homo sapiens_hsa050120.56566974
86Tight junction_Homo sapiens_hsa045300.55948460
87MAPK signaling pathway_Homo sapiens_hsa040100.55382434
88Colorectal cancer_Homo sapiens_hsa052100.55174177
89mTOR signaling pathway_Homo sapiens_hsa041500.55098046
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55027704
91Ras signaling pathway_Homo sapiens_hsa040140.54712208
92Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.53141945
93Renal cell carcinoma_Homo sapiens_hsa052110.52774763
94Choline metabolism in cancer_Homo sapiens_hsa052310.52725666
95Vibrio cholerae infection_Homo sapiens_hsa051100.52723886
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51894109
97Inositol phosphate metabolism_Homo sapiens_hsa005620.51831132
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.51662695
99Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50698328
100Huntingtons disease_Homo sapiens_hsa050160.50266578
101Glycerolipid metabolism_Homo sapiens_hsa005610.50128091
102Ovarian steroidogenesis_Homo sapiens_hsa049130.47959591
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.46050743
104Type II diabetes mellitus_Homo sapiens_hsa049300.44501036
105Endometrial cancer_Homo sapiens_hsa052130.44008545
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43790500
107Sphingolipid metabolism_Homo sapiens_hsa006000.43647999
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42576959
109VEGF signaling pathway_Homo sapiens_hsa043700.42398575
110B cell receptor signaling pathway_Homo sapiens_hsa046620.42121455
111Purine metabolism_Homo sapiens_hsa002300.41818601
112Adherens junction_Homo sapiens_hsa045200.41263947
113Melanoma_Homo sapiens_hsa052180.41255420
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40848496
115Platelet activation_Homo sapiens_hsa046110.40651347
116Oocyte meiosis_Homo sapiens_hsa041140.40066899
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.39667237
118Dilated cardiomyopathy_Homo sapiens_hsa054140.39097571
119Protein digestion and absorption_Homo sapiens_hsa049740.38008791
120Protein export_Homo sapiens_hsa030600.37324717
121Hedgehog signaling pathway_Homo sapiens_hsa043400.36006357
122Rap1 signaling pathway_Homo sapiens_hsa040150.35753637
123Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35542862
124Regulation of autophagy_Homo sapiens_hsa041400.33705648
125Chemokine signaling pathway_Homo sapiens_hsa040620.32652587
126Acute myeloid leukemia_Homo sapiens_hsa052210.31335647
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.28947223
128Other glycan degradation_Homo sapiens_hsa005110.27859643
129Type I diabetes mellitus_Homo sapiens_hsa049400.27600182
130Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.27332018
131Salmonella infection_Homo sapiens_hsa051320.27215606

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