PLXNC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1NIK/NF-kappaB signaling (GO:0038061)7.30739913
2detection of molecule of bacterial origin (GO:0032490)5.98865173
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.23551785
4microglial cell activation (GO:0001774)4.90754261
5detection of external biotic stimulus (GO:0098581)4.84828937
6detection of other organism (GO:0098543)4.83892108
7response to peptidoglycan (GO:0032494)4.76610624
8negative regulation of interleukin-12 production (GO:0032695)4.67078744
9antigen processing and presentation of endogenous antigen (GO:0019883)4.62814455
10positive regulation of gamma-delta T cell activation (GO:0046645)4.61582012
11cellular extravasation (GO:0045123)4.57320505
12response to host immune response (GO:0052572)4.36610671
13response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.36610671
14growth hormone receptor signaling pathway (GO:0060396)4.36404464
15antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.33944100
16antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.33944100
17macrophage activation (GO:0042116)4.33543420
18detection of biotic stimulus (GO:0009595)4.25031585
19natural killer cell mediated cytotoxicity (GO:0042267)4.18426624
20natural killer cell mediated immunity (GO:0002228)4.18426624
21detection of bacterium (GO:0016045)4.17942742
22negative regulation of cell killing (GO:0031342)4.13088277
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.13088277
24regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 4.08722695
25positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.07196453
26positive regulation of B cell differentiation (GO:0045579)4.05485081
27myeloid dendritic cell differentiation (GO:0043011)4.04818508
28neutrophil mediated immunity (GO:0002446)4.01527699
29positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr4.01047532
30response to host (GO:0075136)3.95831452
31response to host defenses (GO:0052200)3.95831452
32response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.95831452
33myeloid dendritic cell activation (GO:0001773)3.94061363
34necroptotic process (GO:0070266)3.93132919
35regulation of interleukin-12 biosynthetic process (GO:0045075)3.88707551
36negative regulation of lymphocyte mediated immunity (GO:0002707)3.87156996
37neutrophil activation involved in immune response (GO:0002283)3.85216935
38mature B cell differentiation (GO:0002335)3.82150789
39negative thymic T cell selection (GO:0045060)3.77515451
40cellular response to growth hormone stimulus (GO:0071378)3.75760127
41JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.63560437
42production of molecular mediator involved in inflammatory response (GO:0002532)3.62068529
43leukocyte aggregation (GO:0070486)3.61741427
44negative regulation of T cell mediated immunity (GO:0002710)3.59838090
45neutrophil activation (GO:0042119)3.59134022
46regulation of RIG-I signaling pathway (GO:0039535)3.54358434
47positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.50654335
48regulation of interferon-beta biosynthetic process (GO:0045357)3.49791028
49negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.49724829
50positive regulation of antigen processing and presentation (GO:0002579)3.49018402
51dendritic cell differentiation (GO:0097028)3.47791081
52myeloid leukocyte mediated immunity (GO:0002444)3.47217242
53leukocyte migration involved in inflammatory response (GO:0002523)3.46151914
54regulation of B cell differentiation (GO:0045577)3.46037911
55positive regulation of mast cell activation (GO:0033005)3.46023299
56regulation of mast cell degranulation (GO:0043304)3.44693414
57granulocyte activation (GO:0036230)3.44387374
58regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.43475564
59negative T cell selection (GO:0043383)3.42798768
60regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.41793454
61regulation of B cell receptor signaling pathway (GO:0050855)3.41175791
62response to muramyl dipeptide (GO:0032495)3.39163884
63positive regulation of natural killer cell differentiation (GO:0032825)3.38665249
64negative regulation of leukocyte mediated immunity (GO:0002704)3.37582108
65regulation of T-helper 1 cell differentiation (GO:0045625)3.37117360
66regulation of dendritic cell antigen processing and presentation (GO:0002604)3.33971967
67JAK-STAT cascade (GO:0007259)3.32046727
68T-helper 1 type immune response (GO:0042088)3.25664442
69regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.24363501
70regulation of mast cell activation involved in immune response (GO:0033006)3.21818209
71cellular response to interleukin-15 (GO:0071350)3.21625874
72antigen processing and presentation via MHC class Ib (GO:0002475)3.21221127
73interferon-gamma-mediated signaling pathway (GO:0060333)3.20647422
74regulation of necroptotic process (GO:0060544)3.20287554
75regulation of mast cell activation (GO:0033003)3.20211901
76lipopolysaccharide-mediated signaling pathway (GO:0031663)3.18583131
77regulation of myeloid leukocyte mediated immunity (GO:0002886)3.18227605
78regulation of hypersensitivity (GO:0002883)3.14938560
79definitive hemopoiesis (GO:0060216)3.11091498
80programmed necrotic cell death (GO:0097300)3.09313815
81necrotic cell death (GO:0070265)3.08922111
82B cell receptor signaling pathway (GO:0050853)3.08845858
83regulation of leukocyte degranulation (GO:0043300)3.08658039
84positive regulation by symbiont of host defense response (GO:0052509)3.05089718
85modulation by symbiont of host defense response (GO:0052031)3.05089718
86modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.05089718
87modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.05089718
88positive regulation by organism of defense response of other organism involved in symbiotic interact3.05089718
89modulation by symbiont of host immune response (GO:0052553)3.05089718
90positive regulation of mast cell activation involved in immune response (GO:0033008)3.01927831
91positive regulation of mast cell degranulation (GO:0043306)3.01927831
92regulation of gamma-delta T cell differentiation (GO:0045586)3.01802176
93dendritic cell migration (GO:0036336)3.01729693
94macrophage activation involved in immune response (GO:0002281)3.00993119
95leukocyte mediated cytotoxicity (GO:0001909)2.96755131
96positive regulation of toll-like receptor signaling pathway (GO:0034123)2.95970933
97regulation of gamma-delta T cell activation (GO:0046643)2.94121464
98negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.93798450
99mature B cell differentiation involved in immune response (GO:0002313)2.92446599
100positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.90231722
101positive regulation of interferon-alpha production (GO:0032727)2.90124194
102positive thymic T cell selection (GO:0045059)2.89403479
103regulation of tolerance induction (GO:0002643)2.87698538
104regulation of macrophage cytokine production (GO:0010935)2.87427690
105myeloid cell activation involved in immune response (GO:0002275)2.86851958
106positive regulation of macrophage cytokine production (GO:0060907)2.84285052
107cellular response to thyroid hormone stimulus (GO:0097067)2.83887116
108regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.83782340
109defense response to protozoan (GO:0042832)2.82835079
110T cell mediated immunity (GO:0002456)2.82800377
111positive regulation of interleukin-2 production (GO:0032743)2.82729454
112dendritic cell chemotaxis (GO:0002407)2.81926263
113neutrophil chemotaxis (GO:0030593)2.80274088
114negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.80231547
115regulation of interleukin-6 biosynthetic process (GO:0045408)2.79965791
116regulation of antigen processing and presentation (GO:0002577)2.79346584
117leukocyte degranulation (GO:0043299)2.79289137
118lymphocyte migration (GO:0072676)2.78688995
119positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.77024490
120positive regulation of humoral immune response (GO:0002922)2.76898494
121germinal center formation (GO:0002467)2.75375461
122response to interleukin-15 (GO:0070672)2.74975207
123positive regulation of cell size (GO:0045793)2.74687772
124positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.74243581
125regulation of regulated secretory pathway (GO:1903305)2.73004547
126neutrophil migration (GO:1990266)2.72974522
127regulation of interferon-alpha production (GO:0032647)2.72780263
128energy homeostasis (GO:0097009)2.72689713
129CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.72072990
130T-helper cell differentiation (GO:0042093)2.72072990
131negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.71509747
132negative regulation of T-helper cell differentiation (GO:0045623)2.71509747
133negative regulation of erythrocyte differentiation (GO:0045647)2.71434062
134lymphocyte mediated immunity (GO:0002449)2.71125413
135immunoglobulin mediated immune response (GO:0016064)2.68537834
136positive regulation of interleukin-12 production (GO:0032735)2.67282248
137positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.65576265
138T cell homeostasis (GO:0043029)2.65442715
139Arp2/3 complex-mediated actin nucleation (GO:0034314)2.62966273
140response to type I interferon (GO:0034340)2.61421170
141regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.61390185
142negative regulation of interleukin-17 production (GO:0032700)2.60899319
143type I interferon signaling pathway (GO:0060337)2.59838348
144cellular response to type I interferon (GO:0071357)2.59838348
145positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.58864038
146B cell homeostasis (GO:0001782)2.58831404
147respiratory burst (GO:0045730)2.56070526
148T cell migration (GO:0072678)2.56036581
149adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.54604184
150myeloid leukocyte activation (GO:0002274)2.53952447
151negative regulation of alpha-beta T cell activation (GO:0046636)2.53549264
152regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.51337556
153positive regulation of cellular amide metabolic process (GO:0034250)2.51203516
154megakaryocyte development (GO:0035855)2.49639587
155regulation of erythrocyte differentiation (GO:0045646)2.49209218
156positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.49193500

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.87112448
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.96380194
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.01161984
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.92432149
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.65192363
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.61762341
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.56382198
8SCL_19346495_ChIP-Seq_HPC-7_Human3.50875662
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.49025107
10GATA1_22025678_ChIP-Seq_K562_Human3.35156666
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.22360205
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.83171843
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.71964106
14* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.68449331
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.65197869
16Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.55045891
17IGF1R_20145208_ChIP-Seq_DFB_Human2.49458528
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.48998062
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.48389032
20RUNX_20019798_ChIP-Seq_JUKART_Human2.36767450
21STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.32390898
22FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.19800930
23SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.14849267
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.03346359
25* TCF7_22412390_ChIP-Seq_EML_Mouse2.01889919
26STAT4_19710469_ChIP-ChIP_TH1__Mouse1.96481019
27* GATA1_19941827_ChIP-Seq_MEL_Mouse1.89969117
28VDR_24787735_ChIP-Seq_THP-1_Human1.85637437
29SPI1_23127762_ChIP-Seq_K562_Human1.84110457
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.83050293
31MAF_26560356_Chip-Seq_TH1_Human1.81605769
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.80426562
33MYB_26560356_Chip-Seq_TH2_Human1.77803107
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74701399
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.74250305
36LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.70487652
37VDR_24763502_ChIP-Seq_THP-1_Human1.68114387
38* SPI1_23547873_ChIP-Seq_NB4_Human1.65357450
39GATA2_21666600_ChIP-Seq_HMVEC_Human1.63835033
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61598031
41MYB_26560356_Chip-Seq_TH1_Human1.61009799
42* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.58093243
43VDR_21846776_ChIP-Seq_THP-1_Human1.57602281
44MYC_22102868_ChIP-Seq_BL_Human1.54982923
45* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.51785773
46PU_27001747_Chip-Seq_BMDM_Mouse1.51445657
47* RUNX1_22412390_ChIP-Seq_EML_Mouse1.50295208
48GATA1_19941826_ChIP-Seq_K562_Human1.50198079
49PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.48826344
50IKZF1_21737484_ChIP-ChIP_HCT116_Human1.47763609
51NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.46898984
52* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.45543572
53* KDM2B_26808549_Chip-Seq_DND41_Human1.45435917
54* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.44416622
55LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.43706932
56SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.41503195
57* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40445977
58* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.37649821
59GATA3_26560356_Chip-Seq_TH2_Human1.35612298
60GATA3_27048872_Chip-Seq_THYMUS_Human1.32573580
61* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.30399938
62KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25842422
63GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19158228
64GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.17732779
65UTX_26944678_Chip-Seq_JUKART_Human1.16627943
66THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.16245136
67* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16217112
68GATA2_19941826_ChIP-Seq_K562_Human1.08872884
69PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08106285
70MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06894495
71CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06656937
72CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04791446
73* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.02210186
74SMRT_27268052_Chip-Seq_Bcells_Human0.99599519
75KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.96974334
76CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96410366
77* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.95385997
78* KDM2B_26808549_Chip-Seq_JURKAT_Human0.93476057
79EGR1_19032775_ChIP-ChIP_M12_Human0.93184487
80VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.91847312
81SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.91154674
82STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90527598
83SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.89669719
84* MAF_26560356_Chip-Seq_TH2_Human0.89307250
85PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88868768
86CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86742143
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.86129365
88* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.80825399
89RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.78743543
90GATA3_26560356_Chip-Seq_TH1_Human0.78096293
91DROSHA_22980978_ChIP-Seq_HELA_Human0.77481410
92* KDM2B_26808549_Chip-Seq_K562_Human0.75764860
93NR3C1_23031785_ChIP-Seq_PC12_Mouse0.74841860
94FOXO3_23340844_ChIP-Seq_DLD1_Human0.72577032
95SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.72113575
96ELK3_25401928_ChIP-Seq_HUVEC_Human0.70697376
97CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70099255
98PU.1_20513432_ChIP-Seq_Bcells_Mouse0.70047490
99SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.69489033
100* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.69332951
101CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.69278577
102FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.69156406
103RXR_22108803_ChIP-Seq_LS180_Human0.67900115
104STAT6_21828071_ChIP-Seq_BEAS2B_Human0.66801372
105TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.65420074
106LXR_22158963_ChIP-Seq_LIVER_Mouse0.61891221
107FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.61187118
108TFEB_21752829_ChIP-Seq_HELA_Human0.60610684
109FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.60380344
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.57323356
111AHR_22903824_ChIP-Seq_MCF-7_Human0.57180665
112NOTCH1_21737748_ChIP-Seq_TLL_Human0.56447757
113FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.54804122
114RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.54019046
115* AR_25329375_ChIP-Seq_VCAP_Human0.53346951
116BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.53344302

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002138_abnormal_hepatobiliary_system4.31376500
2MP0000569_abnormal_digit_pigmentation4.14357367
3MP0001835_abnormal_antigen_presentation4.01604049
4MP0004510_myositis3.95751899
5MP0002254_reproductive_system_inflammat3.18529171
6MP0000685_abnormal_immune_system2.74066438
7MP0005174_abnormal_tail_pigmentation2.66364342
8MP0002166_altered_tumor_susceptibility2.65676932
9MP0003436_decreased_susceptibility_to2.50276039
10MP0008260_abnormal_autophagy2.49383164
11MP0005387_immune_system_phenotype2.45668840
12MP0001790_abnormal_immune_system2.45668840
13MP0001800_abnormal_humoral_immune2.39655661
14MP0002148_abnormal_hypersensitivity_rea2.32974535
15MP0005397_hematopoietic_system_phenotyp2.26859977
16MP0001545_abnormal_hematopoietic_system2.26859977
17MP0002452_abnormal_antigen_presenting2.25282990
18MP0002419_abnormal_innate_immunity2.24824260
19MP0005000_abnormal_immune_tolerance2.22273947
20MP0002009_preneoplasia2.21638192
21MP0001348_abnormal_lacrimal_gland2.19054051
22MP0005464_abnormal_platelet_physiology2.16373056
23MP0003303_peritoneal_inflammation2.15278150
24MP0005671_abnormal_response_to2.15100001
25MP0004381_abnormal_hair_follicle2.14837214
26MP0002723_abnormal_immune_serum2.09057166
27MP0003828_pulmonary_edema2.05545642
28MP0001819_abnormal_immune_cell2.00008157
29MP0005025_abnormal_response_to1.99867442
30MP0002420_abnormal_adaptive_immunity1.99155609
31MP0002006_tumorigenesis1.97010765
32MP0001968_abnormal_touch/_nociception1.94555979
33MP0009785_altered_susceptibility_to1.93433719
34MP0002396_abnormal_hematopoietic_system1.90490459
35MP0005451_abnormal_body_composition1.88518437
36MP0005310_abnormal_salivary_gland1.85940952
37MP0002398_abnormal_bone_marrow1.79815815
38MP0009278_abnormal_bone_marrow1.77659713
39MP0000604_amyloidosis1.75014629
40MP0002736_abnormal_nociception_after1.67790232
41MP0004883_abnormal_blood_vessel1.67450868
42MP0004808_abnormal_hematopoietic_stem1.66342155
43MP0000716_abnormal_immune_system1.66027679
44MP0003172_abnormal_lysosome_physiology1.63828102
45MP0004859_abnormal_synaptic_plasticity1.60667121
46MP0002877_abnormal_melanocyte_morpholog1.58366516
47MP0003191_abnormal_cellular_cholesterol1.56986701
48MP0003690_abnormal_glial_cell1.55614725
49MP0003283_abnormal_digestive_organ1.53304251
50MP0005058_abnormal_lysosome_morphology1.47104806
51MP0000015_abnormal_ear_pigmentation1.44145970
52MP0001853_heart_inflammation1.43765929
53MP0002132_abnormal_respiratory_system1.43034398
54MP0002163_abnormal_gland_morphology1.40780199
55MP0002735_abnormal_chemical_nociception1.39756637
56MP0000689_abnormal_spleen_morphology1.39655426
57MP0003300_gastrointestinal_ulcer1.38552262
58MP0003656_abnormal_erythrocyte_physiolo1.33842234
59MP0002429_abnormal_blood_cell1.33646958
60MP0000858_altered_metastatic_potential1.31883399
61MP0001873_stomach_inflammation1.30529432
62MP0001986_abnormal_taste_sensitivity1.28642163
63MP0005164_abnormal_response_to1.24374034
64MP0009333_abnormal_splenocyte_physiolog1.21521596
65MP0002722_abnormal_immune_system1.20687790
66MP0004947_skin_inflammation1.19886591
67MP0001845_abnormal_inflammatory_respons1.19132284
68MP0002095_abnormal_skin_pigmentation1.17026917
69MP0009764_decreased_sensitivity_to1.15301928
70MP0002405_respiratory_system_inflammati1.14743481
71MP0008469_abnormal_protein_level1.07568393
72MP0005075_abnormal_melanosome_morpholog1.07066217
73MP0001851_eye_inflammation1.06511174
74MP0000371_diluted_coat_color1.05346735
75MP0003724_increased_susceptibility_to1.04066552
76MP0006082_CNS_inflammation1.02448475
77MP0003183_abnormal_peptide_metabolism1.02341757
78MP0010155_abnormal_intestine_physiology1.02043197
79MP0003221_abnormal_cardiomyocyte_apopto0.98133706
80MP0003252_abnormal_bile_duct0.95085457
81MP0005166_decreased_susceptibility_to0.92668444
82MP0000465_gastrointestinal_hemorrhage0.91297979
83MP0003943_abnormal_hepatobiliary_system0.91233948
84MP0000343_altered_response_to0.89131397
85MP0001533_abnormal_skeleton_physiology0.88475539
86MP0002277_abnormal_respiratory_mucosa0.88161895
87MP0003329_amyloid_beta_deposits0.87495569
88MP0003045_fibrosis0.86878632
89MP0003763_abnormal_thymus_physiology0.86324241
90MP0005408_hypopigmentation0.85117723
91MP0005379_endocrine/exocrine_gland_phen0.82613735
92MP0000703_abnormal_thymus_morphology0.82253190
93MP0008874_decreased_physiological_sensi0.80433326
94MP0002733_abnormal_thermal_nociception0.78526821
95MP0003787_abnormal_imprinting0.77489722
96MP0003635_abnormal_synaptic_transmissio0.77305206
97MP0003448_altered_tumor_morphology0.77218374
98MP0005423_abnormal_somatic_nervous0.76914654
99MP0004858_abnormal_nervous_system0.75524262
100MP0003091_abnormal_cell_migration0.73798908
101MP0006054_spinal_hemorrhage0.73318028
102MP0008872_abnormal_physiological_respon0.73070089
103MP0004130_abnormal_muscle_cell0.72458452
104MP0003880_abnormal_central_pattern0.69003153
105MP0002998_abnormal_bone_remodeling0.68372796
106MP0005390_skeleton_phenotype0.68230644
107MP0002332_abnormal_exercise_endurance0.68029504
108MP0008877_abnormal_DNA_methylation0.67104612
109MP0009840_abnormal_foam_cell0.66956931
110MP0009046_muscle_twitch0.66914877
111MP0000920_abnormal_myelination0.66662385
112MP0003075_altered_response_to0.66316510
113MP0005167_abnormal_blood-brain_barrier0.65476692
114MP0001663_abnormal_digestive_system0.65078505
115MP0004484_altered_response_of0.64961977
116MP0008004_abnormal_stomach_pH0.64893316
117MP0005409_darkened_coat_color0.64027779
118MP0003866_abnormal_defecation0.62743431
119MP0002933_joint_inflammation0.61860980
120MP0009745_abnormal_behavioral_response0.61576483
121MP0002064_seizures0.61479121
122MP0009765_abnormal_xenobiotic_induced0.61132860
123MP0001970_abnormal_pain_threshold0.60571781
124MP0000249_abnormal_blood_vessel0.59899133
125MP0000372_irregular_coat_pigmentation0.59097242
126MP0003795_abnormal_bone_structure0.58119619
127MP0002133_abnormal_respiratory_system0.58094923
128MP0005388_respiratory_system_phenotype0.58094923
129MP0010352_gastrointestinal_tract_polyps0.57158371
130MP0002928_abnormal_bile_duct0.53264050
131MP0009763_increased_sensitivity_to0.52311535
132MP0002063_abnormal_learning/memory/cond0.52106555

Predicted human phenotypes

RankGene SetZ-score
1Recurrent bacterial skin infections (HP:0005406)4.87111237
2Recurrent abscess formation (HP:0002722)4.72501260
3Eczematoid dermatitis (HP:0000976)4.40198674
4Stomatitis (HP:0010280)4.19383202
5Recurrent fungal infections (HP:0002841)4.13913059
6Keratoconjunctivitis sicca (HP:0001097)3.93988587
7Recurrent viral infections (HP:0004429)3.90625104
8Abnormal delayed hypersensitivity skin test (HP:0002963)3.72431297
9T lymphocytopenia (HP:0005403)3.68558886
10Recurrent gram-negative bacterial infections (HP:0005420)3.68553011
11Increased cerebral lipofuscin (HP:0011813)3.66870234
12Keratoconjunctivitis (HP:0001096)3.62579301
13Mediastinal lymphadenopathy (HP:0100721)3.57611291
14Gingival bleeding (HP:0000225)3.56968787
15Abnormality of T cell number (HP:0011839)3.47743388
16Abnormality of glycolipid metabolism (HP:0010969)3.42278019
17Abnormality of liposaccharide metabolism (HP:0010968)3.42278019
18Abnormality of glycosphingolipid metabolism (HP:0004343)3.42278019
19Thrombocytosis (HP:0001894)3.39904217
20Fatigue (HP:0012378)3.35987541
21Recurrent skin infections (HP:0001581)3.30920830
22Increased neuronal autofluorescent lipopigment (HP:0002074)3.23229767
23Prolonged bleeding time (HP:0003010)3.18142463
24Peritonitis (HP:0002586)3.15035273
25Myocardial infarction (HP:0001658)3.13668787
26Hemoptysis (HP:0002105)3.13272900
27Urticaria (HP:0001025)3.10069587
28Autoimmune thrombocytopenia (HP:0001973)3.00733154
29Periodontitis (HP:0000704)3.00276792
30Abnormality of macrophages (HP:0004311)2.98450602
31Recurrent cutaneous fungal infections (HP:0011370)2.91456040
32Chronic mucocutaneous candidiasis (HP:0002728)2.91456040
33Chronic otitis media (HP:0000389)2.89747838
34Vasculitis (HP:0002633)2.89537497
35Agammaglobulinemia (HP:0004432)2.87041981
36Visual hallucinations (HP:0002367)2.86755427
37Epistaxis (HP:0000421)2.84980779
38Arterial thrombosis (HP:0004420)2.83568259
39Cellulitis (HP:0100658)2.79183082
40Hematochezia (HP:0002573)2.78809053
41Myositis (HP:0100614)2.77256042
42Pulmonary embolism (HP:0002204)2.74903256
43Colitis (HP:0002583)2.73280535
44Gingivitis (HP:0000230)2.72557044
45Progressive inability to walk (HP:0002505)2.70167484
46Optic neuritis (HP:0100653)2.64929436
47Retrobulbar optic neuritis (HP:0100654)2.64929436
48Abnormality of the thoracic spine (HP:0100711)2.63500415
49Absent frontal sinuses (HP:0002688)2.62460783
50Panhypogammaglobulinemia (HP:0003139)2.62408783
51Petechiae (HP:0000967)2.59441732
52Episodic fever (HP:0001954)2.57648066
53Increased IgE level (HP:0003212)2.56924912
54Gastrointestinal infarctions (HP:0005244)2.52596368
55Acute myeloid leukemia (HP:0004808)2.51505811
56Anorexia (HP:0002039)2.50902318
57Gangrene (HP:0100758)2.49779336
58Meningitis (HP:0001287)2.49435542
59Elevated erythrocyte sedimentation rate (HP:0003565)2.47449716
60Abnormality of the peritoneum (HP:0002585)2.47305006
61Abnormality of T cells (HP:0002843)2.46118198
62Orchitis (HP:0100796)2.45225586
63Leukocytosis (HP:0001974)2.43626801
64Abnormality of the fingertips (HP:0001211)2.43280365
65Pulmonary infiltrates (HP:0002113)2.42711368
66Polycythemia (HP:0001901)2.40890878
67Hypochromic microcytic anemia (HP:0004840)2.38865337
68Prostate neoplasm (HP:0100787)2.37677064
69Inflammation of the large intestine (HP:0002037)2.37229007
70Subacute progressive viral hepatitis (HP:0006572)2.36633704
71Abnormal platelet function (HP:0011869)2.32006130
72Impaired platelet aggregation (HP:0003540)2.32006130
73Abnormality of the pleura (HP:0002103)2.28266820
74Nasal polyposis (HP:0100582)2.27043888
75Chronic obstructive pulmonary disease (HP:0006510)2.26656783
76Obstructive lung disease (HP:0006536)2.26656783
77Supranuclear gaze palsy (HP:0000605)2.24400951
78Abnormality of the columella (HP:0009929)2.23980013
79Anhidrosis (HP:0000970)2.23723502
80Slow saccadic eye movements (HP:0000514)2.23279886
81Osteomyelitis (HP:0002754)2.21833304
82Gastrointestinal stroma tumor (HP:0100723)2.21348222
83Spontaneous hematomas (HP:0007420)2.21282164
84Glomerulopathy (HP:0100820)2.20623358
85Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.20489265
86Dysostosis multiplex (HP:0000943)2.20234672
87Gastrointestinal inflammation (HP:0004386)2.19212709
88Abnormality of the periventricular white matter (HP:0002518)2.19012428
89Viral hepatitis (HP:0006562)2.16116442
90Chest pain (HP:0100749)2.15144437
91Cerebral hemorrhage (HP:0001342)2.14072061
92Tetraparesis (HP:0002273)2.13447668
93Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.12659194
94Abnormality of the endocardium (HP:0004306)2.10931278
95Abnormality of the nasal mucosa (HP:0000433)2.10821675
96Increased IgM level (HP:0003496)2.10397726
97Spontaneous abortion (HP:0005268)2.09639918
98Hypochromic anemia (HP:0001931)2.09009408
99Sepsis (HP:0100806)2.06884081
100Recurrent bronchitis (HP:0002837)2.06733693
101Loss of speech (HP:0002371)2.05712249
102Menorrhagia (HP:0000132)2.04246549
103Mucopolysacchariduria (HP:0008155)2.03358653
104Urinary glycosaminoglycan excretion (HP:0003541)2.03358653
105Cortical dysplasia (HP:0002539)2.03212105
106Urinary bladder sphincter dysfunction (HP:0002839)2.01447755
107Interstitial pulmonary disease (HP:0006530)2.00736441
108Vertigo (HP:0002321)2.00000501
109Granulocytopenia (HP:0001913)1.99570165
110Polyneuropathy (HP:0001271)1.99288446
111Vacuolated lymphocytes (HP:0001922)1.97355856
112Amyloidosis (HP:0011034)1.97140155
113Abnormality of mucopolysaccharide metabolism (HP:0011020)1.96420356
114Abnormality of polysaccharide metabolism (HP:0011012)1.96420356
115Abnormality of glycosaminoglycan metabolism (HP:0004371)1.96420356
116Papilledema (HP:0001085)1.96316544
117Disinhibition (HP:0000734)1.96113045
118Submucous cleft hard palate (HP:0000176)1.95433246
119Acne (HP:0001061)1.93244858
120Hypergammaglobulinemia (HP:0010702)1.91819066
121Ocular albinism (HP:0001107)1.91090717
122Eosinophilia (HP:0001880)1.90297619
123Pustule (HP:0200039)1.89767233
124Cheilitis (HP:0100825)1.89331790
125Focal motor seizures (HP:0011153)1.89151099
126Keratitis (HP:0000491)1.88352161
127Febrile seizures (HP:0002373)1.88347739
128Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.88254274
129Encephalitis (HP:0002383)1.87870341
130Abnormal platelet volume (HP:0011876)1.87790507
131Microcytic anemia (HP:0001935)1.86747007
132Abnormal hair whorl (HP:0010721)1.84586051
133Focal seizures (HP:0007359)1.84378760
134Iris hypopigmentation (HP:0007730)1.84226997
135Sensorimotor neuropathy (HP:0007141)1.83985213
136Thyroiditis (HP:0100646)1.83919527
137Thrombophlebitis (HP:0004418)1.83024398
138Recurrent pneumonia (HP:0006532)1.81916591
139Abnormality of the vasculature of the conjunctiva (HP:0008054)1.79380179
140Acute hepatic failure (HP:0006554)1.77919282
141Purpura (HP:0000979)1.76765209

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K143.82684469
2RIPK43.51584829
3MAP3K133.48872638
4TYK22.91559902
5JAK32.78835930
6KIT2.65888258
7NTRK32.65447888
8IKBKB2.57179038
9TBK12.28137173
10KSR22.27910853
11MAP4K12.27313761
12BRD42.17185376
13IKBKE2.16006101
14TAOK32.06635986
15JAK12.05202992
16IRAK41.98839465
17RET1.93927405
18PRPF4B1.88497911
19CHUK1.87110112
20ERN11.80433268
21TXK1.78709733
22SYK1.75255957
23MAP3K21.72521073
24MAP3K91.63570388
25CSF1R1.60259481
26FGFR31.51809223
27MAP3K31.45198730
28SIK21.44947054
29MATK1.43928347
30MAP3K61.37952205
31JAK21.36351060
32FES1.35907277
33IRAK21.35622165
34MAP3K121.32793153
35ZAP701.32620192
36TAOK11.32381652
37MAP2K31.29683973
38PRKCH1.25948516
39MAP3K111.21976273
40EPHA31.21912995
41FLT31.19468018
42BTK1.16652742
43MAP2K41.16238370
44BLK1.13638968
45MARK31.13450247
46PIK3CG1.09210043
47PRKD21.07779027
48ITK1.05520987
49RAF11.04812224
50TGFBR20.99721419
51FGFR40.99474884
52NEK90.99064006
53MAP2K60.98458166
54EPHB10.98106724
55LCK0.95831744
56MARK20.94603036
57HCK0.94235705
58MAP3K10.93907926
59SGK30.93321930
60PRKAA20.88865678
61DAPK20.87508620
62PIM10.86702745
63MINK10.86128316
64ACVR1B0.85516596
65WNK10.85146718
66MAP2K70.81214407
67SGK10.75182182
68SGK20.73910202
69MAP3K50.73775878
70TEC0.72440624
71HIPK20.72401398
72SIK30.71164806
73RPS6KA20.71114904
74CAMKK20.71106958
75BMX0.70302665
76PTK2B0.69509894
77PDK10.68562877
78NLK0.68160936
79CDK90.67887405
80GRK70.67082232
81CDK190.66945027
82SCYL20.66417388
83GRK60.66132463
84DAPK10.65229668
85LYN0.63235478
86YES10.61402801
87PKN10.60288810
88PTK60.59485767
89MAP3K40.59476297
90TAOK20.56527353
91SGK2230.54387096
92SGK4940.54387096
93MAPK70.53807398
94MAPK120.52282227
95STK100.51057781
96LRRK20.50993994
97BMPR20.50693985
98FRK0.50532971
99PRKCZ0.50469521
100KSR10.50453008
101CDC42BPA0.49894104
102TRIB30.49652176
103PRKCD0.48296199
104TNK20.48128304
105CAMKK10.46645614
106MARK10.45483550
107DYRK1B0.45227687
108NTRK10.44849680
109GRK50.44685457
110STK240.43695577
111STK110.43608946
112RPS6KL10.42108881
113RPS6KC10.42108881
114IRAK10.40118282
115CDK50.39656049
116PKN20.39159107
117MAP3K70.38851777
118ALK0.38632212
119EGFR0.38621440
120IRAK30.38458396
121CAMK40.37749891
122PRKCE0.37433878
123PDPK10.36492696
124TGFBR10.36205760
125GSK3A0.35657020
126PRKCQ0.35631025
127FYN0.34636425
128MUSK0.33647285
129STK40.33614360
130CSK0.33006094
131MAPK40.33005391
132CDK60.32852852
133RIPK10.32205865
134RPS6KA60.31767350
135FGR0.31616201
136RPS6KA10.30216587

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.75019888
2Osteoclast differentiation_Homo sapiens_hsa043802.34782828
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.33893586
4B cell receptor signaling pathway_Homo sapiens_hsa046622.30163175
5NOD-like receptor signaling pathway_Homo sapiens_hsa046212.03364314
6Toll-like receptor signaling pathway_Homo sapiens_hsa046201.96029877
7Autoimmune thyroid disease_Homo sapiens_hsa053201.78904349
8TNF signaling pathway_Homo sapiens_hsa046681.77801584
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.77645727
10Measles_Homo sapiens_hsa051621.76170282
11Toxoplasmosis_Homo sapiens_hsa051451.74920835
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.68632652
13Chemokine signaling pathway_Homo sapiens_hsa040621.65798074
14Dorso-ventral axis formation_Homo sapiens_hsa043201.58928630
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.56574237
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.56072217
17Prolactin signaling pathway_Homo sapiens_hsa049171.54278056
18Tuberculosis_Homo sapiens_hsa051521.52238688
19Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.50844900
20Allograft rejection_Homo sapiens_hsa053301.50711650
21Apoptosis_Homo sapiens_hsa042101.49450108
22Neurotrophin signaling pathway_Homo sapiens_hsa047221.42994934
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.42855508
24Other glycan degradation_Homo sapiens_hsa005111.42517436
25Acute myeloid leukemia_Homo sapiens_hsa052211.41043608
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.40018005
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.39228607
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.38935221
29Pertussis_Homo sapiens_hsa051331.38319000
30Primary immunodeficiency_Homo sapiens_hsa053401.37029836
31Platelet activation_Homo sapiens_hsa046111.32240833
32Influenza A_Homo sapiens_hsa051641.30967622
33Staphylococcus aureus infection_Homo sapiens_hsa051501.27502126
34Shigellosis_Homo sapiens_hsa051311.25981268
35Antigen processing and presentation_Homo sapiens_hsa046121.21203188
36Chronic myeloid leukemia_Homo sapiens_hsa052201.19757919
37Asthma_Homo sapiens_hsa053101.18729638
38Hematopoietic cell lineage_Homo sapiens_hsa046401.14790787
39T cell receptor signaling pathway_Homo sapiens_hsa046601.13843446
40Type II diabetes mellitus_Homo sapiens_hsa049301.11147744
41Glycosaminoglycan degradation_Homo sapiens_hsa005311.11128072
42Hepatitis B_Homo sapiens_hsa051611.06368303
43Leukocyte transendothelial migration_Homo sapiens_hsa046701.05562455
44Graft-versus-host disease_Homo sapiens_hsa053321.04731701
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04285161
46Morphine addiction_Homo sapiens_hsa050321.02621943
47Olfactory transduction_Homo sapiens_hsa047401.01593196
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00574561
49Salmonella infection_Homo sapiens_hsa051321.00237299
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.96181158
51Non-small cell lung cancer_Homo sapiens_hsa052230.93089429
52African trypanosomiasis_Homo sapiens_hsa051430.92378972
53Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.92366825
54Herpes simplex infection_Homo sapiens_hsa051680.91945002
55Renal cell carcinoma_Homo sapiens_hsa052110.91898297
56Circadian entrainment_Homo sapiens_hsa047130.87219730
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.85521692
58Glutamatergic synapse_Homo sapiens_hsa047240.84561025
59Glioma_Homo sapiens_hsa052140.83883342
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.83852012
61Hepatitis C_Homo sapiens_hsa051600.82769674
62Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82647590
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82178610
64Sphingolipid signaling pathway_Homo sapiens_hsa040710.82164927
65Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81842561
66Pancreatic cancer_Homo sapiens_hsa052120.81656859
67Renin secretion_Homo sapiens_hsa049240.81145768
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.80640959
69FoxO signaling pathway_Homo sapiens_hsa040680.76885179
70Cholinergic synapse_Homo sapiens_hsa047250.76434644
71Lysosome_Homo sapiens_hsa041420.76175201
72GnRH signaling pathway_Homo sapiens_hsa049120.76041623
73MAPK signaling pathway_Homo sapiens_hsa040100.75034173
74Nicotine addiction_Homo sapiens_hsa050330.73752144
75Synaptic vesicle cycle_Homo sapiens_hsa047210.73731876
76Phagosome_Homo sapiens_hsa041450.73638562
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.72001976
78VEGF signaling pathway_Homo sapiens_hsa043700.71076745
79Endometrial cancer_Homo sapiens_hsa052130.70876871
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.70462192
81Long-term potentiation_Homo sapiens_hsa047200.69790250
82Viral myocarditis_Homo sapiens_hsa054160.69332317
83Inositol phosphate metabolism_Homo sapiens_hsa005620.69132212
84Type I diabetes mellitus_Homo sapiens_hsa049400.69066592
85Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68157530
86Rheumatoid arthritis_Homo sapiens_hsa053230.66995005
87Estrogen signaling pathway_Homo sapiens_hsa049150.66702498
88Adipocytokine signaling pathway_Homo sapiens_hsa049200.65741156
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65436627
90mTOR signaling pathway_Homo sapiens_hsa041500.64962853
91Amoebiasis_Homo sapiens_hsa051460.64904368
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64481101
93Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62734037
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62528060
95Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62359931
96GABAergic synapse_Homo sapiens_hsa047270.61472412
97Legionellosis_Homo sapiens_hsa051340.61437583
98Endocytosis_Homo sapiens_hsa041440.61025996
99Oxytocin signaling pathway_Homo sapiens_hsa049210.60441698
100HIF-1 signaling pathway_Homo sapiens_hsa040660.59889707
101Insulin resistance_Homo sapiens_hsa049310.59801034
102Malaria_Homo sapiens_hsa051440.59756791
103Notch signaling pathway_Homo sapiens_hsa043300.58972687
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58855509
105Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.57799126
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57223725
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57131913
108Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56966600
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56947949
110Salivary secretion_Homo sapiens_hsa049700.55204113
111Long-term depression_Homo sapiens_hsa047300.55011620
112Epstein-Barr virus infection_Homo sapiens_hsa051690.54784707
113Choline metabolism in cancer_Homo sapiens_hsa052310.54011337
114ErbB signaling pathway_Homo sapiens_hsa040120.53100723
115Complement and coagulation cascades_Homo sapiens_hsa046100.52300604
116Small cell lung cancer_Homo sapiens_hsa052220.51651689
117Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50879888
118Viral carcinogenesis_Homo sapiens_hsa052030.49770821
119Prostate cancer_Homo sapiens_hsa052150.46884779
120Colorectal cancer_Homo sapiens_hsa052100.42810646
121Rap1 signaling pathway_Homo sapiens_hsa040150.38126662
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35179318

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