PLXND1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vascular endothelial growth factor signaling pathway (GO:0038084)4.42778316
2plasma membrane repair (GO:0001778)4.40515725
3negative regulation of erythrocyte differentiation (GO:0045647)3.98427034
4barbed-end actin filament capping (GO:0051016)3.86328721
5cardiac myofibril assembly (GO:0055003)3.85143946
6basement membrane organization (GO:0071711)3.80353822
7cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.75175212
8negative regulation of blood vessel endothelial cell migration (GO:0043537)3.68317234
9pinocytosis (GO:0006907)3.65033758
10retina vasculature morphogenesis in camera-type eye (GO:0061299)3.54707113
11mannose metabolic process (GO:0006013)3.51394394
12lymph vessel development (GO:0001945)3.50969361
13low-density lipoprotein particle clearance (GO:0034383)3.28813127
14positive regulation of receptor recycling (GO:0001921)3.26147526
15myofibril assembly (GO:0030239)3.21895524
16positive regulation by symbiont of host defense response (GO:0052509)3.20685319
17modulation by symbiont of host defense response (GO:0052031)3.20685319
18modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.20685319
19modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.20685319
20positive regulation by organism of defense response of other organism involved in symbiotic interact3.20685319
21modulation by symbiont of host immune response (GO:0052553)3.20685319
22cellular response to thyroid hormone stimulus (GO:0097067)3.17933131
23regulation of cholesterol storage (GO:0010885)3.15459307
24blood vessel maturation (GO:0001955)3.09357797
25wound healing, spreading of epidermal cells (GO:0035313)3.07956049
26positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.03209158
27regulation of cell migration involved in sprouting angiogenesis (GO:0090049)3.03075343
28morphogenesis of an endothelium (GO:0003159)3.03063932
29endothelial tube morphogenesis (GO:0061154)3.03063932
30sarcomere organization (GO:0045214)3.02607993
31protein localization to endosome (GO:0036010)3.02421176
32endodermal cell differentiation (GO:0035987)3.02096961
33heart trabecula formation (GO:0060347)3.01845083
34negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.97549268
35substrate-dependent cell migration (GO:0006929)2.96278872
36endothelial cell morphogenesis (GO:0001886)2.95928845
37negative regulation of focal adhesion assembly (GO:0051895)2.92186962
38negative regulation of cell junction assembly (GO:1901889)2.92186962
39negative regulation of adherens junction organization (GO:1903392)2.92186962
40growth hormone receptor signaling pathway (GO:0060396)2.89380010
41glycosphingolipid catabolic process (GO:0046479)2.89172148
42cell adhesion mediated by integrin (GO:0033627)2.87695678
43axon extension involved in axon guidance (GO:0048846)2.85779509
44neuron projection extension involved in neuron projection guidance (GO:1902284)2.85779509
45endothelium development (GO:0003158)2.85085907
46response to peptidoglycan (GO:0032494)2.84964571
47cell migration involved in heart development (GO:0060973)2.80649852
48cell migration involved in sprouting angiogenesis (GO:0002042)2.79908726
49cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.77771981
50blood vessel endothelial cell migration (GO:0043534)2.77096378
51vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.75595165
52negative regulation of potassium ion transmembrane transport (GO:1901380)2.75286693
53response to laminar fluid shear stress (GO:0034616)2.72586106
54surfactant homeostasis (GO:0043129)2.69546476
55bundle of His cell to Purkinje myocyte communication (GO:0086069)2.68982472
56regulation of early endosome to late endosome transport (GO:2000641)2.67971896
57cellular response to growth hormone stimulus (GO:0071378)2.67561941
58regulation of macrophage chemotaxis (GO:0010758)2.67373626
59regulation of blood vessel endothelial cell migration (GO:0043535)2.65161028
60apoptotic cell clearance (GO:0043277)2.64605558
61positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.63726296
62negative regulation of endothelial cell migration (GO:0010596)2.63714435
63virion attachment to host cell (GO:0019062)2.63325415
64adhesion of symbiont to host cell (GO:0044650)2.63325415
65ovulation from ovarian follicle (GO:0001542)2.63200761
66* patterning of blood vessels (GO:0001569)2.61966164
67positive regulation of glycogen biosynthetic process (GO:0045725)2.61761197
68endothelial cell chemotaxis (GO:0035767)2.61603886
69lymphangiogenesis (GO:0001946)2.61325312
70negative regulation of granulocyte differentiation (GO:0030853)2.60068044
71regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.59705173
72positive regulation of endothelial cell apoptotic process (GO:2000353)2.59276818
73adhesion of symbiont to host (GO:0044406)2.59065210
74positive regulation of vasculogenesis (GO:2001214)2.58597700
75stress fiber assembly (GO:0043149)2.58264952
76positive regulation of macrophage cytokine production (GO:0060907)2.58155849
77peptide catabolic process (GO:0043171)2.57702025
78adherens junction assembly (GO:0034333)2.57094667
79negative regulation of interleukin-12 production (GO:0032695)2.56942498
80response to thyroid hormone (GO:0097066)2.56740137
81regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.56435776
82amino sugar catabolic process (GO:0046348)2.56230368
83response to muramyl dipeptide (GO:0032495)2.55145891
84glomerular filtration (GO:0003094)2.55113930
85positive regulation of blood vessel endothelial cell migration (GO:0043536)2.54613189
86regulation of interferon-beta biosynthetic process (GO:0045357)2.54526039
87positive regulation of odontogenesis (GO:0042482)2.53588710
88glycolipid catabolic process (GO:0019377)2.53539580
89response to fluid shear stress (GO:0034405)2.52112982
90* semaphorin-plexin signaling pathway (GO:0071526)2.51605383
91regulation of p38MAPK cascade (GO:1900744)2.51342665
92lipopolysaccharide-mediated signaling pathway (GO:0031663)2.50801689
93keratan sulfate catabolic process (GO:0042340)2.50224376
94angiogenesis involved in wound healing (GO:0060055)2.50165835
95regulation of mononuclear cell migration (GO:0071675)2.49235397
96positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.46920690
97negative regulation of nitric oxide biosynthetic process (GO:0045019)2.45962723
98epithelial cell differentiation involved in prostate gland development (GO:0060742)2.45916064
99macrophage activation involved in immune response (GO:0002281)2.45792095
100cortical actin cytoskeleton organization (GO:0030866)2.45418825
101regulation of endothelial cell differentiation (GO:0045601)2.44998981
102cell communication by electrical coupling (GO:0010644)2.44770454
103regulation of leukocyte degranulation (GO:0043300)2.43335530
104positive regulation of lipid kinase activity (GO:0090218)2.42459925
105G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.42184264
106positive regulation of extracellular matrix organization (GO:1903055)2.42118081
107sprouting angiogenesis (GO:0002040)2.41876858
108negative regulation of platelet activation (GO:0010544)2.40402029
109positive regulation of p38MAPK cascade (GO:1900745)2.39451459
110negative regulation of vascular permeability (GO:0043116)2.38489771
111regulation of membrane protein ectodomain proteolysis (GO:0051043)2.37525935
112positive regulation of lipid storage (GO:0010884)2.37476047
113regulation of ARF GTPase activity (GO:0032312)2.36831165
114endocytic recycling (GO:0032456)2.36491873
115insulin-like growth factor receptor signaling pathway (GO:0048009)2.36031508
116Notch signaling involved in heart development (GO:0061314)2.35997763
117negative regulation of heart growth (GO:0061117)2.34927089
118negative regulation of cardiac muscle tissue growth (GO:0055022)2.34927089
119renal filtration (GO:0097205)2.34872819
120regulation of sequestering of triglyceride (GO:0010889)2.34610823
121coronary vasculature morphogenesis (GO:0060977)2.34534046
122regulation of extracellular matrix disassembly (GO:0010715)2.34133091
123fatty acid transmembrane transport (GO:1902001)2.34087003
124mRNA transcription (GO:0009299)2.33799004
125collagen metabolic process (GO:0032963)2.33077822
126cytoskeletal anchoring at plasma membrane (GO:0007016)2.32886558
127positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.32707982
128cardiac muscle hypertrophy (GO:0003300)2.32100625
129oligosaccharide catabolic process (GO:0009313)2.32053050
130mRNA transcription from RNA polymerase II promoter (GO:0042789)2.31741164
131adenosine receptor signaling pathway (GO:0001973)2.31508613
132negative regulation of cell size (GO:0045792)2.31467127
133cell-substrate junction assembly (GO:0007044)2.31321033
134positive regulation of histone deacetylation (GO:0031065)2.31303628
135detection of molecule of bacterial origin (GO:0032490)2.30903895
136cell communication involved in cardiac conduction (GO:0086065)2.29980055
137focal adhesion assembly (GO:0048041)2.29089502
138cell-substrate adherens junction assembly (GO:0007045)2.29089502
139negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.29046511
140actomyosin structure organization (GO:0031032)2.28921905
141regulation of integrin activation (GO:0033623)2.28585710
142cardiac muscle contraction (GO:0060048)2.28515317
143collagen catabolic process (GO:0030574)2.28170358
144positive regulation of cholesterol efflux (GO:0010875)2.27498582
145fibril organization (GO:0097435)2.27009462
146venous blood vessel morphogenesis (GO:0048845)2.26916131
147positive regulation of gamma-delta T cell activation (GO:0046645)2.26305726
148phagocytosis (GO:0006909)2.24865890
149I-kappaB phosphorylation (GO:0007252)2.24276429
150regulation of T-helper 2 cell differentiation (GO:0045628)2.24201587
151hyaluronan catabolic process (GO:0030214)2.23242016
152establishment of endothelial barrier (GO:0061028)2.22676336
153regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.22258746
154vasculogenesis (GO:0001570)2.22181170
155regulation of vasculogenesis (GO:2001212)2.21244015
156regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.20269080
157regulation of sarcomere organization (GO:0060297)2.19738359
158positive regulation of glycogen metabolic process (GO:0070875)2.18954697
159cAMP biosynthetic process (GO:0006171)2.18875247
160muscle hypertrophy (GO:0014896)2.18759471
161striated muscle hypertrophy (GO:0014897)2.18641071
162regulation of actin filament-based movement (GO:1903115)2.18245681
163antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.17764576
164protein kinase C signaling (GO:0070528)2.17425393
165cardiac muscle cell development (GO:0055013)2.17128597

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.39841402
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.34683949
3BP1_19119308_ChIP-ChIP_Hs578T_Human2.81663477
4* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.46430013
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.37052136
6STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31362921
7* ELK3_25401928_ChIP-Seq_HUVEC_Human2.27454804
8GATA2_21666600_ChIP-Seq_HMVEC_Human2.20641093
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.19662117
10THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.09747161
11CLOCK_20551151_ChIP-Seq_293T_Human2.08412439
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.05548177
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.03979848
14* KDM2B_26808549_Chip-Seq_DND41_Human2.00642223
15TRIM28_21343339_ChIP-Seq_HEK293_Human1.99538094
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.95763740
17IRF8_21731497_ChIP-ChIP_J774_Mouse1.95175750
18* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.86249772
19* IRF8_27001747_Chip-Seq_BMDM_Mouse1.84609928
20* TBX20_22080862_ChIP-Seq_HEART_Mouse1.79699183
21* TBX20_22328084_ChIP-Seq_HEART_Mouse1.79699183
22EP300_21415370_ChIP-Seq_HL-1_Mouse1.75381259
23* TCF7_22412390_ChIP-Seq_EML_Mouse1.74709544
24* SPI1_23127762_ChIP-Seq_K562_Human1.74429075
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.73587006
26TP63_17297297_ChIP-ChIP_HaCaT_Human1.71344737
27* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.71256833
28ZNF263_19887448_ChIP-Seq_K562_Human1.69431932
29* LXR_22292898_ChIP-Seq_THP-1_Human1.67334128
30* KDM2B_26808549_Chip-Seq_K562_Human1.67276885
31* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.63953167
32NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61524148
33Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.60820061
34ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.55550749
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.52950243
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.49432611
37TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.48890186
38CDX2_19796622_ChIP-Seq_MESCs_Mouse1.48392809
39IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.47929195
40PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.46131718
41GATA1_19941826_ChIP-Seq_K562_Human1.45961679
42VDR_21846776_ChIP-Seq_THP-1_Human1.45810301
43ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.45463684
44DROSHA_22980978_ChIP-Seq_HELA_Human1.44127535
45RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.43669196
46ESR1_20079471_ChIP-ChIP_T-47D_Human1.42673285
47SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.42465483
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.42303509
49WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.41602084
50FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.39990401
51NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.39647648
52KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38477519
53* KDM2B_26808549_Chip-Seq_JURKAT_Human1.37394600
54VDR_24787735_ChIP-Seq_THP-1_Human1.35692687
55P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35367418
56MYB_21317192_ChIP-Seq_ERMYB_Mouse1.35361704
57VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.35107144
58TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34992808
59TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33039727
60BRD4_27068464_Chip-Seq_AML-cells_Mouse1.31896468
61* LXR_22158963_ChIP-Seq_LIVER_Mouse1.31325597
62* MAF_26560356_Chip-Seq_TH1_Human1.31298753
63VDR_24763502_ChIP-Seq_THP-1_Human1.30687993
64* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.30305660
65GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30113608
66EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29750159
67* RUNX1_22412390_ChIP-Seq_EML_Mouse1.27819351
68STAT6_21828071_ChIP-Seq_BEAS2B_Human1.25411742
69MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.25229498
70TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.23787915
71* RACK7_27058665_Chip-Seq_MCF-7_Human1.22951006
72MYC_22102868_ChIP-Seq_BL_Human1.20860512
73SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.20517432
74ERG_21242973_ChIP-ChIP_JURKAT_Human1.20238651
75CTCF_27219007_Chip-Seq_ERYTHROID_Human1.19143491
76ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18774613
77DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18017834
78* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16516584
79SMC1_22415368_ChIP-Seq_MEFs_Mouse1.16191065
80SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14769323
81MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14337101
82PPAR_26484153_Chip-Seq_NCI-H1993_Human1.13385692
83ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12353114
84FOXO3_23340844_ChIP-Seq_DLD1_Human1.11902193
85* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10728349
86PPARA_22158963_ChIP-Seq_LIVER_Mouse1.10673759
87RXR_22158963_ChIP-Seq_LIVER_Mouse1.09956474
88CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08513381
89* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08432390
90TP53_22127205_ChIP-Seq_IMR90_Human1.08205097
91BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07146716
92GATA2_19941826_ChIP-Seq_K562_Human1.05739171
93SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05315049
94WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05149115
95ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04587879
96* RUNX_20019798_ChIP-Seq_JUKART_Human1.04585427
97MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04455023
98GATA1_19941827_ChIP-Seq_MEL_Mouse1.04372779
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04217678
100* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.03509423
101TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.03154529
102SOX9_24532713_ChIP-Seq_HFSC_Mouse1.02955025
103UBF1/2_26484160_Chip-Seq_HMECs_Human1.01815000
104FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.01404563
105* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01004537
106PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00867294
107ESR1_21235772_ChIP-Seq_MCF-7_Human0.98551226
108NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.98231983
109SMC4_20622854_ChIP-Seq_HELA_Human0.98098099
110SMC3_22415368_ChIP-Seq_MEFs_Mouse0.98062749
111NCOR1_26117541_ChIP-Seq_K562_Human0.97831355
112* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.96418172
113UTX_26944678_Chip-Seq_JUKART_Human0.95790662
114SCL_19346495_ChIP-Seq_HPC-7_Human0.95478793
115FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95116302
116STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.94687549
117ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.94399364
118CJUN_26792858_Chip-Seq_BT549_Human0.94260671
119GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93520296
120KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93136707
121UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.92761947
122DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92035174
123RUNX1_27514584_Chip-Seq_MCF-7_Human0.91184121
124ZNF217_24962896_ChIP-Seq_MCF-7_Human0.89598465

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010368_abnormal_lymphatic_system5.36219659
2MP0004272_abnormal_basement_membrane3.83786996
3MP0001879_abnormal_lymphatic_vessel3.68954506
4MP0003705_abnormal_hypodermis_morpholog3.53836394
5MP0004084_abnormal_cardiac_muscle3.45554109
6MP0003303_peritoneal_inflammation3.33974610
7MP0005167_abnormal_blood-brain_barrier3.15304017
8MP0004510_myositis3.10683998
9MP0000751_myopathy2.78597917
10MP0003828_pulmonary_edema2.62287577
11MP0008438_abnormal_cutaneous_collagen2.62181492
12MP0002837_dystrophic_cardiac_calcinosis2.36688317
13MP0004130_abnormal_muscle_cell2.28760105
14MP0003279_aneurysm2.24597503
15MP0004036_abnormal_muscle_relaxation2.10624402
16MP0004215_abnormal_myocardial_fiber1.96501708
17MP0003566_abnormal_cell_adhesion1.96395710
18MP0003300_gastrointestinal_ulcer1.92083589
19MP0009278_abnormal_bone_marrow1.90768214
20MP0006054_spinal_hemorrhage1.83465292
21MP0010630_abnormal_cardiac_muscle1.82418480
22MP0005330_cardiomyopathy1.81970295
23MP0004087_abnormal_muscle_fiber1.81328521
24MP0008775_abnormal_heart_ventricle1.78930973
25MP0002877_abnormal_melanocyte_morpholog1.78243122
26MP0001544_abnormal_cardiovascular_syste1.76969723
27MP0005385_cardiovascular_system_phenoty1.76969723
28MP0005409_darkened_coat_color1.74720724
29MP0006138_congestive_heart_failure1.73828823
30MP0006082_CNS_inflammation1.69900331
31MP0002972_abnormal_cardiac_muscle1.69797274
32MP0005257_abnormal_intraocular_pressure1.63528295
33MP0000465_gastrointestinal_hemorrhage1.57389031
34MP0000569_abnormal_digit_pigmentation1.56029998
35MP0002933_joint_inflammation1.55593810
36MP0005623_abnormal_meninges_morphology1.55438799
37MP0005451_abnormal_body_composition1.49610325
38MP0000750_abnormal_muscle_regeneration1.47547602
39MP0001958_emphysema1.46105577
40* MP0000767_abnormal_smooth_muscle1.36370009
41MP0008260_abnormal_autophagy1.36359427
42MP0000343_altered_response_to1.36271858
43MP0000749_muscle_degeneration1.34784715
44MP0005023_abnormal_wound_healing1.32178402
45MP0005058_abnormal_lysosome_morphology1.24190867
46MP0005620_abnormal_muscle_contractility1.24062220
47MP0005076_abnormal_cell_differentiation1.23547296
48MP0002106_abnormal_muscle_physiology1.23065215
49MP0005275_abnormal_skin_tensile1.22787351
50MP0003091_abnormal_cell_migration1.22343608
51MP0003191_abnormal_cellular_cholesterol1.21814545
52MP0004185_abnormal_adipocyte_glucose1.21372201
53MP0004858_abnormal_nervous_system1.21151784
54MP0003646_muscle_fatigue1.20763023
55MP0004085_abnormal_heartbeat1.20504442
56MP0000858_altered_metastatic_potential1.19584225
57MP0009840_abnormal_foam_cell1.16977360
58MP0003172_abnormal_lysosome_physiology1.14839273
59MP0002148_abnormal_hypersensitivity_rea1.14465257
60MP0003329_amyloid_beta_deposits1.13285631
61MP0000733_abnormal_muscle_development1.12984066
62* MP0002128_abnormal_blood_circulation1.11511872
63MP0001835_abnormal_antigen_presentation1.10707784
64MP0002332_abnormal_exercise_endurance1.09662232
65MP0005390_skeleton_phenotype1.08302916
66MP0000249_abnormal_blood_vessel1.06257411
67MP0004484_altered_response_of1.05616585
68MP0002896_abnormal_bone_mineralization1.05205983
69MP0004145_abnormal_muscle_electrophysio1.04515332
70MP0003453_abnormal_keratinocyte_physiol1.02093248
71MP0002166_altered_tumor_susceptibility1.01934028
72* MP0001915_intracranial_hemorrhage1.01747808
73MP0003436_decreased_susceptibility_to1.01042137
74MP0005165_increased_susceptibility_to1.00236511
75MP0005164_abnormal_response_to0.99523701
76MP0002419_abnormal_innate_immunity0.98520177
77* MP0000266_abnormal_heart_morphology0.97249792
78MP0005666_abnormal_adipose_tissue0.97214385
79MP0001853_heart_inflammation0.97041080
80MP0005503_abnormal_tendon_morphology0.96835545
81MP0008961_abnormal_basal_metabolism0.96627941
82* MP0001614_abnormal_blood_vessel0.96382790
83* MP0002925_abnormal_cardiovascular_devel0.96236521
84MP0008004_abnormal_stomach_pH0.94388653
85MP0000759_abnormal_skeletal_muscle0.93420712
86MP0003075_altered_response_to0.91513551
87MP0000685_abnormal_immune_system0.90995375
88MP0003724_increased_susceptibility_to0.90335755
89MP0005369_muscle_phenotype0.90108627
90MP0001542_abnormal_bone_strength0.89710069
91MP0002998_abnormal_bone_remodeling0.89178876
92MP0004233_abnormal_muscle_weight0.88439362
93MP0002138_abnormal_hepatobiliary_system0.88331896
94MP0009785_altered_susceptibility_to0.88257165
95MP0003448_altered_tumor_morphology0.87608437
96MP0002295_abnormal_pulmonary_circulatio0.86664716
97MP0005375_adipose_tissue_phenotype0.86431756
98MP0004883_abnormal_blood_vessel0.86304445
99MP0005508_abnormal_skeleton_morphology0.85573687
100MP0003567_abnormal_fetal_cardiomyocyte0.84960428
101MP0009780_abnormal_chondrocyte_physiolo0.83800435
102MP0009764_decreased_sensitivity_to0.82607110
103MP0005387_immune_system_phenotype0.81972569
104MP0001790_abnormal_immune_system0.81972569
105MP0005464_abnormal_platelet_physiology0.81616831
106MP0003795_abnormal_bone_structure0.81416149
107MP0003221_abnormal_cardiomyocyte_apopto0.81220316
108MP0000604_amyloidosis0.81016942
109MP0002254_reproductive_system_inflammat0.80017282
110MP0002452_abnormal_antigen_presenting0.79660065
111MP0002405_respiratory_system_inflammati0.79381524
112MP0005166_decreased_susceptibility_to0.79266310
113MP0004947_skin_inflammation0.79099630
114MP0003045_fibrosis0.77853802
115MP0005397_hematopoietic_system_phenotyp0.77760645
116MP0001545_abnormal_hematopoietic_system0.77760645
117MP0000013_abnormal_adipose_tissue0.77566761
118MP0003137_abnormal_impulse_conducting0.77298746
119MP0003690_abnormal_glial_cell0.76733464
120MP0010155_abnormal_intestine_physiology0.76732155
121MP0004808_abnormal_hematopoietic_stem0.76059882
122MP0004782_abnormal_surfactant_physiolog0.74877492
123MP0002127_abnormal_cardiovascular_syste0.73812099
124MP0001849_ear_inflammation0.73645306
125MP0005670_abnormal_white_adipose0.73321938
126MP0005595_abnormal_vascular_smooth0.72763553
127MP0000003_abnormal_adipose_tissue0.72111107
128MP0001851_eye_inflammation0.71791430
129MP0001533_abnormal_skeleton_physiology0.71707017
130MP0010352_gastrointestinal_tract_polyps0.71395993
131MP0003634_abnormal_glial_cell0.71128442
132MP0002269_muscular_atrophy0.70179483
133MP0000747_muscle_weakness0.70003787
134MP0005388_respiratory_system_phenotype0.69964292
135MP0002133_abnormal_respiratory_system0.69964292
136MP0005000_abnormal_immune_tolerance0.68688654
137MP0005025_abnormal_response_to0.68173618

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.50157344
2Abnormality of liposaccharide metabolism (HP:0010968)4.50157344
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.50157344
4Cerebral aneurysm (HP:0004944)4.32732797
5Sudden death (HP:0001699)3.93460741
6Protrusio acetabuli (HP:0003179)3.80928105
7Dysostosis multiplex (HP:0000943)3.74570637
8Increased connective tissue (HP:0009025)3.63191653
9Lymphangioma (HP:0100764)3.48557588
10Hematochezia (HP:0002573)3.38056404
11Systemic lupus erythematosus (HP:0002725)3.36407290
12Muscle fiber splitting (HP:0003555)3.29222689
13Abnormality of polysaccharide metabolism (HP:0011012)3.18735320
14Abnormality of glycosaminoglycan metabolism (HP:0004371)3.18735320
15Abnormality of mucopolysaccharide metabolism (HP:0011020)3.18735320
16Ventricular tachycardia (HP:0004756)3.16755433
17Mucopolysacchariduria (HP:0008155)3.16631852
18Urinary glycosaminoglycan excretion (HP:0003541)3.16631852
19Polycythemia (HP:0001901)3.08095957
20Hyporeflexia of lower limbs (HP:0002600)3.06108634
21Asymmetry of the thorax (HP:0001555)3.02831462
22Spontaneous hematomas (HP:0007420)3.02715394
23Difficulty running (HP:0009046)2.98271662
24Asymmetric septal hypertrophy (HP:0001670)2.92895742
25Atrial fibrillation (HP:0005110)2.89103890
26Broad metatarsal (HP:0001783)2.87614616
27Vertebral compression fractures (HP:0002953)2.86729239
28Vacuolated lymphocytes (HP:0001922)2.80488758
29Supraventricular arrhythmia (HP:0005115)2.77788753
30Primary atrial arrhythmia (HP:0001692)2.73054591
31Esophageal varix (HP:0002040)2.71454762
32Abnormality of the left ventricular outflow tract (HP:0011103)2.66964727
33Subaortic stenosis (HP:0001682)2.66964727
34Cervical subluxation (HP:0003308)2.66189907
35Atrioventricular block (HP:0001678)2.65470254
36Aneurysm (HP:0002617)2.63807220
37Nuclear cataract (HP:0100018)2.62927350
38Increased neuronal autofluorescent lipopigment (HP:0002074)2.61421072
39Loss of speech (HP:0002371)2.55421103
40Lipoatrophy (HP:0100578)2.55309469
41Supraventricular tachycardia (HP:0004755)2.54471729
42Wrist flexion contracture (HP:0001239)2.53226425
43Vascular tortuosity (HP:0004948)2.50075267
44Abnormality of the vasculature of the conjunctiva (HP:0008054)2.49628217
45Neurofibrillary tangles (HP:0002185)2.48804504
46Abnormality of macrophages (HP:0004311)2.46352075
47Arterial tortuosity (HP:0005116)2.44774613
48Increased variability in muscle fiber diameter (HP:0003557)2.44516043
49Exercise-induced muscle cramps (HP:0003710)2.43862493
50Myotonia (HP:0002486)2.40277164
51Shallow orbits (HP:0000586)2.40007259
52Difficulty climbing stairs (HP:0003551)2.36963063
53Ankle contracture (HP:0006466)2.36055177
54Eczematoid dermatitis (HP:0000976)2.35087229
55Spondylolisthesis (HP:0003302)2.33404506
56Joint stiffness (HP:0001387)2.32632999
57Increased cerebral lipofuscin (HP:0011813)2.32346774
58Neonatal death (HP:0003811)2.31512807
59Skull defect (HP:0001362)2.28837736
60Subacute progressive viral hepatitis (HP:0006572)2.27041445
61Mitral valve prolapse (HP:0001634)2.22997262
62Heart block (HP:0012722)2.22418175
63Bundle branch block (HP:0011710)2.22116611
64Hemorrhage of the eye (HP:0011885)2.21886398
65J-shaped sella turcica (HP:0002680)2.21102659
66Porencephaly (HP:0002132)2.20414077
67Blue sclerae (HP:0000592)2.20119628
68Abnormality of skeletal muscle fiber size (HP:0012084)2.18992377
69Complement deficiency (HP:0004431)2.18563519
70Overgrowth (HP:0001548)2.18100148
71Myocardial infarction (HP:0001658)2.17549490
72Distal lower limb muscle weakness (HP:0009053)2.17204872
73Spinal rigidity (HP:0003306)2.16007439
74Hemiplegia (HP:0002301)2.15935468
75Abnormality of complement system (HP:0005339)2.15124788
76Amyloidosis (HP:0011034)2.14897876
77Glomerulonephritis (HP:0000099)2.14850351
78Abnormal atrioventricular conduction (HP:0005150)2.14037881
79Wormian bones (HP:0002645)2.13704808
80Right ventricular cardiomyopathy (HP:0011663)2.13245913
81Aortic aneurysm (HP:0004942)2.12383472
82EMG: myopathic abnormalities (HP:0003458)2.11293617
83Type 1 muscle fiber predominance (HP:0003803)2.10781515
84Visceral angiomatosis (HP:0100761)2.07576220
85Syncope (HP:0001279)2.07162437
86Premature rupture of membranes (HP:0001788)2.06804966
87Prolonged QT interval (HP:0001657)2.06254012
88Enlarged penis (HP:0000040)2.04181228
89Abnormality of the calf musculature (HP:0001430)2.03652707
90Cerebral inclusion bodies (HP:0100314)2.03507190
91Tetraparesis (HP:0002273)2.01958999
92Striae distensae (HP:0001065)2.01662861
93Axonal loss (HP:0003447)2.00466295
94Interstitial pulmonary disease (HP:0006530)2.00418468
95Hyperacusis (HP:0010780)2.00401180
96Bladder diverticulum (HP:0000015)2.00174469
97High pitched voice (HP:0001620)2.00133248
98Hemangiomatosis (HP:0007461)1.99650779
99Exercise-induced myalgia (HP:0003738)1.99529364
100Broad face (HP:0000283)1.99416623
101Purpura (HP:0000979)1.97756843
102Lower limb amyotrophy (HP:0007210)1.96645677
103Cerebral hemorrhage (HP:0001342)1.95228333
104Polygenic inheritance (HP:0010982)1.95189714
105Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.94903974
106Short 4th metacarpal (HP:0010044)1.94903974
107Apathy (HP:0000741)1.94430156
108Recurrent abscess formation (HP:0002722)1.93747658
109Genu recurvatum (HP:0002816)1.93630920
110Frequent falls (HP:0002359)1.92998686
111Peritonitis (HP:0002586)1.92693013
112Dilatation of the ascending aorta (HP:0005111)1.91620999
113Thoracic kyphosis (HP:0002942)1.90904485
114Disproportionate tall stature (HP:0001519)1.90468258
115Recurrent gram-negative bacterial infections (HP:0005420)1.90355310
116Thin bony cortex (HP:0002753)1.90306740
117Abnormality of the nasal mucosa (HP:0000433)1.88671217
118Diminished motivation (HP:0000745)1.85887023
119Pulmonary hypertension (HP:0002092)1.84765472
120Autoimmune thrombocytopenia (HP:0001973)1.83029723
121Aortic dissection (HP:0002647)1.82283267
122Long toe (HP:0010511)1.81727531
123Distal lower limb amyotrophy (HP:0008944)1.80959684
124Calf muscle hypertrophy (HP:0008981)1.80459290
125Osteolytic defects of the phalanges of the hand (HP:0009771)1.80362981
126Osteolytic defects of the hand bones (HP:0009699)1.80362981
127Ventricular fibrillation (HP:0001663)1.80317509
128Obstructive sleep apnea (HP:0002870)1.79984046
129Centrally nucleated skeletal muscle fibers (HP:0003687)1.78670546
130Dilated cardiomyopathy (HP:0001644)1.77969731
131Abnormality of the 4th metacarpal (HP:0010012)1.77437152
132Upper motor neuron abnormality (HP:0002127)1.76910373
133Fragile skin (HP:0001030)1.75557702
134Conjunctival telangiectasia (HP:0000524)1.75416374
135Ovoid vertebral bodies (HP:0003300)1.75321061
136Cellulitis (HP:0100658)1.75289569
137Upper limb amyotrophy (HP:0009129)1.74748033
138Distal upper limb amyotrophy (HP:0007149)1.74748033
139Nonimmune hydrops fetalis (HP:0001790)1.74277168
140Arterial thrombosis (HP:0004420)1.73274732
141Mildly elevated creatine phosphokinase (HP:0008180)1.72987412
142Ventricular arrhythmia (HP:0004308)1.72572506
143Venous abnormality (HP:0002624)1.70201848
144Cortical dysplasia (HP:0002539)1.69261125
145Abnormality of the thoracic spine (HP:0100711)1.69108087
146Mitral stenosis (HP:0001718)1.68273629
147Stroke (HP:0001297)1.67925085
148Ectopia lentis (HP:0001083)1.67675851
149Recurrent bacterial skin infections (HP:0005406)1.67639520
150Joint laxity (HP:0001388)1.66940078
151Flexion contracture of toe (HP:0005830)1.66842962
152Joint contractures involving the joints of the feet (HP:0100492)1.66842962
153Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.66750039
154Epistaxis (HP:0000421)1.66198441

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE16.51206006
2TRIB34.17683631
3PKN23.65924585
4KDR3.52935304
5TTN2.94727923
6RIPK12.70953017
7PRPF4B2.42937187
8ERN12.23257099
9IRAK32.18070845
10TGFBR22.14416005
11SCYL22.09494680
12PTK61.95079509
13SIK21.76846277
14DMPK1.75329958
15PTK2B1.68175141
16DDR21.63138802
17EPHB11.59011526
18MAP3K101.53762496
19CDC42BPA1.42704588
20PDGFRA1.39607464
21SMG11.37793226
22MAP4K11.36587358
23TBK11.28021328
24TYK21.27232176
25LMTK21.23199012
26NME21.19958046
27TESK11.19428564
28PHKG21.16801397
29PHKG11.16801397
30FGFR41.16521278
31CAMK1D1.14551004
32RIPK41.13323880
33DAPK21.11849486
34JAK11.10737959
35KSR21.09632609
36CAMK1G1.09211084
37EPHB21.08919831
38BMX1.08831212
39RET1.05488241
40SIK11.00276409
41TAOK20.98608398
42PRKD20.98129951
43PDGFRB0.98110384
44TGFBR10.97534157
45FGFR30.95969959
46CAMKK10.95678378
47MAP3K60.94065924
48MOS0.93633199
49MAP2K30.93387529
50MAP3K140.91152340
51PRKD30.88523423
52PRKCH0.88223589
53LRRK20.87547022
54PRKD10.82406132
55MAPK120.81967422
56MAPK70.81724049
57MAP3K70.81468234
58JAK30.78729719
59TYRO30.78217453
60PAK40.76960968
61FGR0.76832004
62KIT0.75002064
63JAK20.72935837
64CSK0.71950115
65FES0.70141170
66HCK0.69466627
67RPS6KL10.69053193
68RPS6KC10.69053193
69ABL20.68822194
70MYLK0.68741894
71TRPM70.68294643
72PRKG20.67938848
73ILK0.67093031
74PTK20.66427397
75MAP3K10.64595896
76PAK60.64491832
77TESK20.62171808
78RPS6KA20.61567735
79ZAP700.60878105
80MATK0.60594338
81LATS20.57913108
82PDPK10.57662382
83MTOR0.57395616
84ALK0.57103324
85ICK0.57063610
86MARK10.55288301
87MAPKAPK30.54254456
88NTRK10.54127552
89LATS10.53914041
90MAP3K130.53557437
91EGFR0.53276367
92BLK0.52840515
93STK240.51689398
94PRKAA20.51310575
95MAP3K110.50518722
96NEK90.50122343
97MAP3K90.50045183
98DAPK30.49943373
99SRC0.49210301
100TAOK10.49156781
101RPS6KA60.48222538
102ARAF0.47584639
103EEF2K0.46891205
104FLT30.46294714
105MARK20.45919696
106PDK10.45913096
107MARK30.45857418
108MAPK40.45580687
109CDK120.44548509
110HIPK20.43695509
111FYN0.43159374
112EPHA30.42958582
113SGK30.42523543
114CDK60.42001667
115BTK0.41431322
116PIM20.40834567
117PAK20.39716300
118NEK10.39472361
119LCK0.38776235
120GRK70.38748284
121CSF1R0.38288010
122IKBKE0.37996166
123CHUK0.37715891
124IRAK40.37226382
125ROCK10.35810680
126MAP3K30.33618461
127CAMK40.33152639
128ROCK20.33088440
129GSK3A0.33082305
130FER0.32703056
131SYK0.32010889
132PRKAA10.31762867

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.74889381
2Dilated cardiomyopathy_Homo sapiens_hsa054141.92523283
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.83392371
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.78519741
5Viral myocarditis_Homo sapiens_hsa054161.75692501
6ECM-receptor interaction_Homo sapiens_hsa045121.65189725
7Amoebiasis_Homo sapiens_hsa051461.60576784
8Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.60044860
9Focal adhesion_Homo sapiens_hsa045101.59681495
10Osteoclast differentiation_Homo sapiens_hsa043801.55150262
11Leishmaniasis_Homo sapiens_hsa051401.52560368
12AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.49820281
13Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.49489504
14Toxoplasmosis_Homo sapiens_hsa051451.45901909
15Dorso-ventral axis formation_Homo sapiens_hsa043201.37045184
16Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.34768762
17Bladder cancer_Homo sapiens_hsa052191.34571178
18Insulin resistance_Homo sapiens_hsa049311.32350756
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.28922058
20Leukocyte transendothelial migration_Homo sapiens_hsa046701.27698388
21Small cell lung cancer_Homo sapiens_hsa052221.26199353
22Staphylococcus aureus infection_Homo sapiens_hsa051501.25242789
23VEGF signaling pathway_Homo sapiens_hsa043701.22915363
24Chronic myeloid leukemia_Homo sapiens_hsa052201.22657892
25Adipocytokine signaling pathway_Homo sapiens_hsa049201.22368401
26Platelet activation_Homo sapiens_hsa046111.21637001
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21602809
28Phagosome_Homo sapiens_hsa041451.20686503
29Rheumatoid arthritis_Homo sapiens_hsa053231.18587440
30B cell receptor signaling pathway_Homo sapiens_hsa046621.17370910
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17329711
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16409592
33Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.16170812
34Type II diabetes mellitus_Homo sapiens_hsa049301.14642395
35Proteoglycans in cancer_Homo sapiens_hsa052051.14178429
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.10375015
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.06688031
38Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.06403495
39Tuberculosis_Homo sapiens_hsa051521.06399446
40Adherens junction_Homo sapiens_hsa045201.05157563
41Pertussis_Homo sapiens_hsa051331.03688352
42Neurotrophin signaling pathway_Homo sapiens_hsa047221.03115752
43TNF signaling pathway_Homo sapiens_hsa046680.97104606
44Glycosaminoglycan degradation_Homo sapiens_hsa005310.97058693
45Chemokine signaling pathway_Homo sapiens_hsa040620.96867161
46Renin secretion_Homo sapiens_hsa049240.94269127
47Salmonella infection_Homo sapiens_hsa051320.93857384
48Lysosome_Homo sapiens_hsa041420.93616243
49Arginine biosynthesis_Homo sapiens_hsa002200.93382206
50PPAR signaling pathway_Homo sapiens_hsa033200.92518433
51Glioma_Homo sapiens_hsa052140.92454423
52Aldosterone synthesis and secretion_Homo sapiens_hsa049250.92135758
53HIF-1 signaling pathway_Homo sapiens_hsa040660.90376877
54Estrogen signaling pathway_Homo sapiens_hsa049150.89111119
55Malaria_Homo sapiens_hsa051440.88381449
56Renal cell carcinoma_Homo sapiens_hsa052110.87546558
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87251078
58Notch signaling pathway_Homo sapiens_hsa043300.86867705
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86336510
60Fatty acid degradation_Homo sapiens_hsa000710.86173970
61Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84588515
62Rap1 signaling pathway_Homo sapiens_hsa040150.84585370
63Insulin signaling pathway_Homo sapiens_hsa049100.83957014
64Lysine degradation_Homo sapiens_hsa003100.83148867
65mTOR signaling pathway_Homo sapiens_hsa041500.82172863
66Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81943021
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80762644
68Acute myeloid leukemia_Homo sapiens_hsa052210.79950761
69Pancreatic cancer_Homo sapiens_hsa052120.79641222
70African trypanosomiasis_Homo sapiens_hsa051430.78551226
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77180045
72Hematopoietic cell lineage_Homo sapiens_hsa046400.76760102
73Regulation of actin cytoskeleton_Homo sapiens_hsa048100.76664354
74Hepatitis C_Homo sapiens_hsa051600.76590813
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.74934457
76Galactose metabolism_Homo sapiens_hsa000520.74924988
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.74889995
78Oxytocin signaling pathway_Homo sapiens_hsa049210.73909639
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73096674
80Endometrial cancer_Homo sapiens_hsa052130.72370563
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72315299
82Vibrio cholerae infection_Homo sapiens_hsa051100.71833005
83Influenza A_Homo sapiens_hsa051640.71104546
84Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68776496
85Non-small cell lung cancer_Homo sapiens_hsa052230.68575089
86Endocytosis_Homo sapiens_hsa041440.68506052
87Apoptosis_Homo sapiens_hsa042100.68073945
88Central carbon metabolism in cancer_Homo sapiens_hsa052300.67653395
89Protein digestion and absorption_Homo sapiens_hsa049740.66710664
90Shigellosis_Homo sapiens_hsa051310.65919603
91Prolactin signaling pathway_Homo sapiens_hsa049170.65684651
92Nitrogen metabolism_Homo sapiens_hsa009100.64655328
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.64396756
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64347052
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64314100
96Axon guidance_Homo sapiens_hsa043600.63345886
97Pentose phosphate pathway_Homo sapiens_hsa000300.63021303
98Measles_Homo sapiens_hsa051620.62759518
99PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62735746
100Fatty acid metabolism_Homo sapiens_hsa012120.61364550
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60529124
102Complement and coagulation cascades_Homo sapiens_hsa046100.60494226
103Gastric acid secretion_Homo sapiens_hsa049710.59788796
104Legionellosis_Homo sapiens_hsa051340.59741589
105Bile secretion_Homo sapiens_hsa049760.59588694
106Hepatitis B_Homo sapiens_hsa051610.59194429
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58218908
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.57808826
109AMPK signaling pathway_Homo sapiens_hsa041520.57289457
110GnRH signaling pathway_Homo sapiens_hsa049120.56712435
111Gap junction_Homo sapiens_hsa045400.56436648
112cAMP signaling pathway_Homo sapiens_hsa040240.56221286
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56169611
114Vascular smooth muscle contraction_Homo sapiens_hsa042700.55395862
115Pathways in cancer_Homo sapiens_hsa052000.54894479
116Choline metabolism in cancer_Homo sapiens_hsa052310.54744214
117Cholinergic synapse_Homo sapiens_hsa047250.54272798
118MicroRNAs in cancer_Homo sapiens_hsa052060.54069308
119Prion diseases_Homo sapiens_hsa050200.53489828
120Asthma_Homo sapiens_hsa053100.53472636
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.53372979
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.51299864
123Ras signaling pathway_Homo sapiens_hsa040140.51061508
124Allograft rejection_Homo sapiens_hsa053300.50685469
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48900445
126Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47838279
127Sphingolipid metabolism_Homo sapiens_hsa006000.47768399

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