

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.90982995 |
| 2 | viral transcription (GO:0019083) | 4.80793719 |
| 3 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.75426557 |
| 4 | translational termination (GO:0006415) | 4.69221770 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.66157840 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 4.58287733 |
| 7 | protein targeting to ER (GO:0045047) | 4.54497360 |
| 8 | protein localization to endoplasmic reticulum (GO:0070972) | 4.40858289 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.38873173 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.38873173 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.38873173 |
| 12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.36211250 |
| 13 | protein complex biogenesis (GO:0070271) | 4.27852804 |
| 14 | DNA deamination (GO:0045006) | 4.13225250 |
| 15 | translational elongation (GO:0006414) | 4.12664973 |
| 16 | ribosomal large subunit biogenesis (GO:0042273) | 4.07619580 |
| 17 | ribosomal small subunit biogenesis (GO:0042274) | 4.06062759 |
| 18 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.04807406 |
| 19 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.03026773 |
| 20 | deoxyribonucleotide catabolic process (GO:0009264) | 4.00351487 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.97824416 |
| 22 | maturation of SSU-rRNA (GO:0030490) | 3.93722753 |
| 23 | rRNA modification (GO:0000154) | 3.93584949 |
| 24 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.93170006 |
| 25 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.92600707 |
| 26 | microtubule severing (GO:0051013) | 3.89556249 |
| 27 | deoxyribose phosphate catabolic process (GO:0046386) | 3.87356810 |
| 28 | viral life cycle (GO:0019058) | 3.77058149 |
| 29 | translational initiation (GO:0006413) | 3.76085014 |
| 30 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.63477304 |
| 31 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.61846451 |
| 32 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.60494911 |
| 33 | protein neddylation (GO:0045116) | 3.56216592 |
| 34 | ATP synthesis coupled proton transport (GO:0015986) | 3.49998262 |
| 35 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.49998262 |
| 36 | cellular protein complex disassembly (GO:0043624) | 3.49501986 |
| 37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49448362 |
| 38 | translation (GO:0006412) | 3.47458850 |
| 39 | response to pheromone (GO:0019236) | 3.47314903 |
| 40 | mismatch repair (GO:0006298) | 3.45631486 |
| 41 | purine nucleotide salvage (GO:0032261) | 3.45458069 |
| 42 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.44229083 |
| 43 | termination of RNA polymerase III transcription (GO:0006386) | 3.44229083 |
| 44 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.43933060 |
| 45 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.43338082 |
| 46 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.43127880 |
| 47 | positive regulation of B cell differentiation (GO:0045579) | 3.41259578 |
| 48 | GTP biosynthetic process (GO:0006183) | 3.38762384 |
| 49 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.36954311 |
| 50 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.35142820 |
| 51 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.34919107 |
| 52 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.33643129 |
| 53 | organelle disassembly (GO:1903008) | 3.33528806 |
| 54 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.31033060 |
| 55 | deoxyribose phosphate metabolic process (GO:0019692) | 3.30085304 |
| 56 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.23944421 |
| 57 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.23944421 |
| 58 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.20287719 |
| 59 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.20287719 |
| 60 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.20287719 |
| 61 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.19203257 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.19203257 |
| 63 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.16385923 |
| 64 | base-excision repair, AP site formation (GO:0006285) | 3.15853304 |
| 65 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.15761561 |
| 66 | centriole replication (GO:0007099) | 3.14295252 |
| 67 | rRNA methylation (GO:0031167) | 3.13625809 |
| 68 | oxidative phosphorylation (GO:0006119) | 3.12199867 |
| 69 | purine-containing compound salvage (GO:0043101) | 3.07623438 |
| 70 | platelet dense granule organization (GO:0060155) | 3.07147851 |
| 71 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.06530372 |
| 72 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.06530372 |
| 73 | cellular component biogenesis (GO:0044085) | 3.04453749 |
| 74 | UTP metabolic process (GO:0046051) | 3.03890281 |
| 75 | protein targeting to membrane (GO:0006612) | 3.03743298 |
| 76 | negative regulation of ligase activity (GO:0051352) | 3.03556939 |
| 77 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.03556939 |
| 78 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.02028119 |
| 79 | aldehyde catabolic process (GO:0046185) | 3.01613844 |
| 80 | UTP biosynthetic process (GO:0006228) | 3.01389594 |
| 81 | grooming behavior (GO:0007625) | 3.01180314 |
| 82 | actin nucleation (GO:0045010) | 2.99858695 |
| 83 | protein complex disassembly (GO:0043241) | 2.99833976 |
| 84 | deoxyribonucleotide metabolic process (GO:0009262) | 2.99525462 |
| 85 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.97951596 |
| 86 | arginine catabolic process (GO:0006527) | 2.97165581 |
| 87 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.96356348 |
| 88 | macromolecular complex disassembly (GO:0032984) | 2.94709899 |
| 89 | purine deoxyribonucleotide metabolic process (GO:0009151) | 2.91741615 |
| 90 | purine nucleobase biosynthetic process (GO:0009113) | 2.91460094 |
| 91 | respiratory electron transport chain (GO:0022904) | 2.90457201 |
| 92 | electron transport chain (GO:0022900) | 2.89862796 |
| 93 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.89221312 |
| 94 | pseudouridine synthesis (GO:0001522) | 2.88303991 |
| 95 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.88197114 |
| 96 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.87845910 |
| 97 | heme biosynthetic process (GO:0006783) | 2.83755422 |
| 98 | protein maturation by protein folding (GO:0022417) | 2.82225288 |
| 99 | aggressive behavior (GO:0002118) | 2.81742072 |
| 100 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.79509856 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.51438639 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.05895829 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.04985086 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.75667981 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.65384487 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.63399078 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.57271679 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.42425601 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.12601198 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 3.04513487 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.04033678 |
| 12 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.92428803 |
| 13 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.90829997 |
| 14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.87029992 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.72012364 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.71227243 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.63906601 |
| 18 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.60573652 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.58927224 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.46101773 |
| 21 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.43475764 |
| 22 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.31435178 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.31053584 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.22222003 |
| 25 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.20852059 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.14003015 |
| 27 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.12311519 |
| 28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.09716946 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.07401485 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.05827216 |
| 31 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.03710699 |
| 32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.01823536 |
| 33 | GATA1_22025678_ChIP-Seq_K562_Human | 2.01749622 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.01190862 |
| 35 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.99664347 |
| 36 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.98087050 |
| 37 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.96115207 |
| 38 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.83721723 |
| 39 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.82670240 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.80701471 |
| 41 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.80462328 |
| 42 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.80286236 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.80005275 |
| 44 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76684788 |
| 45 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.72470066 |
| 46 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.69328518 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.64525988 |
| 48 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56644209 |
| 49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.53053110 |
| 50 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.50480345 |
| 51 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.46422403 |
| 52 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.44779201 |
| 53 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.41915385 |
| 54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41556122 |
| 55 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.40042327 |
| 56 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.39490810 |
| 57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37216048 |
| 58 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.36823907 |
| 59 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.33735952 |
| 60 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.30094231 |
| 61 | MYB_26560356_Chip-Seq_TH2_Human | 1.29197943 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.26605121 |
| 63 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.25301783 |
| 64 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.23257400 |
| 65 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.18234671 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.17066404 |
| 67 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13277308 |
| 68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.10799202 |
| 69 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.04644890 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.04619054 |
| 71 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03915858 |
| 72 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.03405477 |
| 73 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02684731 |
| 74 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00094901 |
| 75 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.98071908 |
| 76 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.97371180 |
| 77 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94908203 |
| 78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.94201101 |
| 79 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.93472465 |
| 80 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.93044312 |
| 81 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.92215632 |
| 82 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.92021655 |
| 83 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90805679 |
| 84 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.90184738 |
| 85 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.89495724 |
| 86 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.87676873 |
| 87 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85886858 |
| 88 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.85610544 |
| 89 | VDR_22108803_ChIP-Seq_LS180_Human | 0.85314545 |
| 90 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.83942931 |
| 91 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.82352409 |
| 92 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82194078 |
| 93 | EWS_26573619_Chip-Seq_HEK293_Human | 0.81548636 |
| 94 | MYC_22102868_ChIP-Seq_BL_Human | 0.81437787 |
| 95 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.80584850 |
| 96 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.80122414 |
| 97 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.79377309 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.79377309 |
| 99 | MYB_26560356_Chip-Seq_TH1_Human | 0.78756504 |
| 100 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.77695431 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009697_abnormal_copulation | 3.61716904 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.61520841 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 3.48188161 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 3.34095289 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 3.09423675 |
| 6 | MP0002132_abnormal_respiratory_system | 2.89683158 |
| 7 | MP0004147_increased_porphyrin_level | 2.86882820 |
| 8 | MP0008058_abnormal_DNA_repair | 2.81766855 |
| 9 | MP0006036_abnormal_mitochondrial_physio | 2.64777851 |
| 10 | MP0003186_abnormal_redox_activity | 2.45064244 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.43956385 |
| 12 | MP0000685_abnormal_immune_system | 2.21164111 |
| 13 | MP0003718_maternal_effect | 2.17058680 |
| 14 | MP0009379_abnormal_foot_pigmentation | 2.14089147 |
| 15 | MP0009785_altered_susceptibility_to | 2.11268314 |
| 16 | MP0001727_abnormal_embryo_implantation | 2.05470312 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.02401588 |
| 18 | MP0006035_abnormal_mitochondrial_morpho | 2.01179296 |
| 19 | MP0003787_abnormal_imprinting | 1.95237502 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.94381045 |
| 21 | MP0002736_abnormal_nociception_after | 1.88423860 |
| 22 | MP0005671_abnormal_response_to | 1.77000048 |
| 23 | MP0008789_abnormal_olfactory_epithelium | 1.75475876 |
| 24 | MP0000372_irregular_coat_pigmentation | 1.72851910 |
| 25 | MP0003763_abnormal_thymus_physiology | 1.72507346 |
| 26 | MP0002837_dystrophic_cardiac_calcinosis | 1.71973039 |
| 27 | MP0003693_abnormal_embryo_hatching | 1.55613406 |
| 28 | MP0002166_altered_tumor_susceptibility | 1.51002137 |
| 29 | MP0005000_abnormal_immune_tolerance | 1.46966673 |
| 30 | MP0006292_abnormal_olfactory_placode | 1.44282271 |
| 31 | MP0001800_abnormal_humoral_immune | 1.43013248 |
| 32 | MP0002138_abnormal_hepatobiliary_system | 1.41001385 |
| 33 | MP0000689_abnormal_spleen_morphology | 1.40037222 |
| 34 | MP0002653_abnormal_ependyma_morphology | 1.36338003 |
| 35 | MP0002398_abnormal_bone_marrow | 1.35215001 |
| 36 | MP0002148_abnormal_hypersensitivity_rea | 1.31682627 |
| 37 | MP0003786_premature_aging | 1.31252727 |
| 38 | MP0003252_abnormal_bile_duct | 1.30836163 |
| 39 | MP0001819_abnormal_immune_cell | 1.29800488 |
| 40 | MP0002452_abnormal_antigen_presenting | 1.29717374 |
| 41 | MP0001529_abnormal_vocalization | 1.29073731 |
| 42 | MP0002420_abnormal_adaptive_immunity | 1.27792292 |
| 43 | MP0001905_abnormal_dopamine_level | 1.27225466 |
| 44 | MP0002095_abnormal_skin_pigmentation | 1.25393596 |
| 45 | MP0002254_reproductive_system_inflammat | 1.21739660 |
| 46 | MP0008872_abnormal_physiological_respon | 1.19382123 |
| 47 | MP0003077_abnormal_cell_cycle | 1.18198550 |
| 48 | MP0005646_abnormal_pituitary_gland | 1.18072730 |
| 49 | MP0002396_abnormal_hematopoietic_system | 1.18057967 |
| 50 | MP0002160_abnormal_reproductive_system | 1.17672906 |
| 51 | MP0002006_tumorigenesis | 1.17529516 |
| 52 | MP0003283_abnormal_digestive_organ | 1.17310854 |
| 53 | MP0002723_abnormal_immune_serum | 1.16973159 |
| 54 | MP0001790_abnormal_immune_system | 1.16288992 |
| 55 | MP0005387_immune_system_phenotype | 1.16288992 |
| 56 | MP0005394_taste/olfaction_phenotype | 1.15292390 |
| 57 | MP0005499_abnormal_olfactory_system | 1.15292390 |
| 58 | MP0001873_stomach_inflammation | 1.14272628 |
| 59 | MP0005408_hypopigmentation | 1.14192375 |
| 60 | MP0002019_abnormal_tumor_incidence | 1.13954550 |
| 61 | MP0002722_abnormal_immune_system | 1.12917791 |
| 62 | MP0005025_abnormal_response_to | 1.11448707 |
| 63 | MP0005636_abnormal_mineral_homeostasis | 1.10140426 |
| 64 | MP0000716_abnormal_immune_system | 1.08990773 |
| 65 | MP0006082_CNS_inflammation | 1.07390413 |
| 66 | MP0000358_abnormal_cell_content/ | 1.07096381 |
| 67 | MP0002405_respiratory_system_inflammati | 1.06943780 |
| 68 | MP0002429_abnormal_blood_cell | 1.05900264 |
| 69 | MP0004142_abnormal_muscle_tone | 1.03009856 |
| 70 | MP0008875_abnormal_xenobiotic_pharmacok | 1.00597631 |
| 71 | MP0009333_abnormal_splenocyte_physiolog | 0.99213382 |
| 72 | MP0006072_abnormal_retinal_apoptosis | 0.95961810 |
| 73 | MP0003111_abnormal_nucleus_morphology | 0.91865124 |
| 74 | MP0009764_decreased_sensitivity_to | 0.91115891 |
| 75 | MP0002234_abnormal_pharynx_morphology | 0.90856301 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.90349531 |
| 77 | MP0005165_increased_susceptibility_to | 0.90214148 |
| 78 | MP0003121_genomic_imprinting | 0.88441721 |
| 79 | MP0008877_abnormal_DNA_methylation | 0.84062121 |
| 80 | MP0001968_abnormal_touch/_nociception | 0.83699080 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.81887624 |
| 82 | MP0008007_abnormal_cellular_replicative | 0.80544304 |
| 83 | MP0008932_abnormal_embryonic_tissue | 0.78626650 |
| 84 | MP0008469_abnormal_protein_level | 0.78606683 |
| 85 | MP0005389_reproductive_system_phenotype | 0.76565205 |
| 86 | MP0003866_abnormal_defecation | 0.75014791 |
| 87 | MP0005395_other_phenotype | 0.74748037 |
| 88 | MP0001845_abnormal_inflammatory_respons | 0.74745331 |
| 89 | MP0001542_abnormal_bone_strength | 0.73584940 |
| 90 | MP0002090_abnormal_vision | 0.71424409 |
| 91 | MP0009763_increased_sensitivity_to | 0.71264721 |
| 92 | MP0003656_abnormal_erythrocyte_physiolo | 0.70781350 |
| 93 | MP0002928_abnormal_bile_duct | 0.70618147 |
| 94 | MP0005220_abnormal_exocrine_pancreas | 0.70384211 |
| 95 | MP0005310_abnormal_salivary_gland | 0.70073513 |
| 96 | MP0000313_abnormal_cell_death | 0.69929551 |
| 97 | MP0005332_abnormal_amino_acid | 0.69777569 |
| 98 | MP0000490_abnormal_crypts_of | 0.69628743 |
| 99 | MP0009053_abnormal_anal_canal | 0.69600740 |
| 100 | MP0005330_cardiomyopathy | 0.67225512 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.26663971 |
| 2 | Panhypogammaglobulinemia (HP:0003139) | 4.52195159 |
| 3 | Acute encephalopathy (HP:0006846) | 4.37875479 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.31704543 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.25001732 |
| 6 | Mitochondrial inheritance (HP:0001427) | 4.19146772 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.17963164 |
| 8 | Renal Fanconi syndrome (HP:0001994) | 4.05933564 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 4.01664445 |
| 10 | Increased CSF lactate (HP:0002490) | 3.91326274 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.75363251 |
| 12 | Hepatic necrosis (HP:0002605) | 3.65148071 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.53877713 |
| 14 | Agammaglobulinemia (HP:0004432) | 3.41794069 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 3.31086337 |
| 16 | Reticulocytopenia (HP:0001896) | 3.26005998 |
| 17 | Increased intramyocellular lipid droplets (HP:0012240) | 3.25274265 |
| 18 | B lymphocytopenia (HP:0010976) | 3.24841573 |
| 19 | Microvesicular hepatic steatosis (HP:0001414) | 3.08214729 |
| 20 | Abnormality of B cell number (HP:0010975) | 2.97588552 |
| 21 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.96166114 |
| 22 | Increased serum lactate (HP:0002151) | 2.95495852 |
| 23 | Cerebral edema (HP:0002181) | 2.87986045 |
| 24 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.80086015 |
| 25 | Abnormality of the prostate (HP:0008775) | 2.76031489 |
| 26 | Increased muscle lipid content (HP:0009058) | 2.73212198 |
| 27 | Combined immunodeficiency (HP:0005387) | 2.71635929 |
| 28 | Lactic acidosis (HP:0003128) | 2.63440798 |
| 29 | Pancytopenia (HP:0001876) | 2.61650499 |
| 30 | Abnormal number of erythroid precursors (HP:0012131) | 2.61241121 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.59515708 |
| 32 | Hypoproteinemia (HP:0003075) | 2.54872907 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.53381403 |
| 34 | Cerebral palsy (HP:0100021) | 2.51869108 |
| 35 | Abnormality of renal resorption (HP:0011038) | 2.50709880 |
| 36 | Exertional dyspnea (HP:0002875) | 2.48371960 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.45932357 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.45932357 |
| 39 | Type I transferrin isoform profile (HP:0003642) | 2.43060603 |
| 40 | Hypoplasia of the thymus (HP:0000778) | 2.42847999 |
| 41 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.38299831 |
| 42 | Obstructive lung disease (HP:0006536) | 2.38087247 |
| 43 | Chronic obstructive pulmonary disease (HP:0006510) | 2.38087247 |
| 44 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.36660199 |
| 45 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.36660199 |
| 46 | Abnormality of lateral ventricle (HP:0030047) | 2.32515142 |
| 47 | Recurrent viral infections (HP:0004429) | 2.29746730 |
| 48 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.27368098 |
| 49 | Pancreatic fibrosis (HP:0100732) | 2.26509377 |
| 50 | Prolonged neonatal jaundice (HP:0006579) | 2.21696897 |
| 51 | Exercise intolerance (HP:0003546) | 2.21185321 |
| 52 | Microretrognathia (HP:0000308) | 2.19023688 |
| 53 | Emotional lability (HP:0000712) | 2.15312847 |
| 54 | Thrombocytosis (HP:0001894) | 2.14991733 |
| 55 | Pancreatic cysts (HP:0001737) | 2.12442089 |
| 56 | Leukodystrophy (HP:0002415) | 2.12278412 |
| 57 | Prolonged bleeding time (HP:0003010) | 2.09378551 |
| 58 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.08397333 |
| 59 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.08058820 |
| 60 | Absent/shortened dynein arms (HP:0200106) | 2.08058820 |
| 61 | Increased serum pyruvate (HP:0003542) | 2.07892730 |
| 62 | Respiratory failure (HP:0002878) | 2.06613441 |
| 63 | Medial flaring of the eyebrow (HP:0010747) | 2.06345456 |
| 64 | Thyroiditis (HP:0100646) | 2.03988116 |
| 65 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.02292582 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.01800491 |
| 67 | Abnormal protein glycosylation (HP:0012346) | 2.01800491 |
| 68 | Abnormal glycosylation (HP:0012345) | 2.01800491 |
| 69 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.01800491 |
| 70 | CNS hypomyelination (HP:0003429) | 2.01519316 |
| 71 | Meningitis (HP:0001287) | 1.98245183 |
| 72 | Neutropenia (HP:0001875) | 1.97630722 |
| 73 | CNS demyelination (HP:0007305) | 1.97568283 |
| 74 | Posterior subcapsular cataract (HP:0007787) | 1.96768898 |
| 75 | Chronic otitis media (HP:0000389) | 1.95898713 |
| 76 | Cerebral hypomyelination (HP:0006808) | 1.95546253 |
| 77 | Oral leukoplakia (HP:0002745) | 1.95058588 |
| 78 | Lethargy (HP:0001254) | 1.93108165 |
| 79 | Brushfield spots (HP:0001088) | 1.92519071 |
| 80 | Short tibia (HP:0005736) | 1.90215238 |
| 81 | Chromsome breakage (HP:0040012) | 1.87435889 |
| 82 | Pallor (HP:0000980) | 1.86284152 |
| 83 | Optic disc pallor (HP:0000543) | 1.84947090 |
| 84 | Abnormality of T cells (HP:0002843) | 1.82974888 |
| 85 | Median cleft lip (HP:0000161) | 1.82470407 |
| 86 | Macrocytic anemia (HP:0001972) | 1.81016105 |
| 87 | Abnormality of methionine metabolism (HP:0010901) | 1.78663153 |
| 88 | Type 2 muscle fiber atrophy (HP:0003554) | 1.76930739 |
| 89 | Progressive microcephaly (HP:0000253) | 1.76458269 |
| 90 | IgM deficiency (HP:0002850) | 1.76350907 |
| 91 | Stomatitis (HP:0010280) | 1.75674133 |
| 92 | Congenital primary aphakia (HP:0007707) | 1.74590622 |
| 93 | Abnormality of reticulocytes (HP:0004312) | 1.74331352 |
| 94 | Abnormality of glycolysis (HP:0004366) | 1.73168940 |
| 95 | Abnormality of T cell physiology (HP:0011840) | 1.72609840 |
| 96 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.72199555 |
| 97 | Hyperglycinemia (HP:0002154) | 1.70549296 |
| 98 | Poor suck (HP:0002033) | 1.69139756 |
| 99 | Lymphoma (HP:0002665) | 1.68878165 |
| 100 | Abnormality of male internal genitalia (HP:0000022) | 1.68876430 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.05153775 |
| 2 | STK16 | 3.64636216 |
| 3 | MST4 | 3.31930672 |
| 4 | CCNB1 | 3.24935564 |
| 5 | SCYL2 | 3.12200319 |
| 6 | NUAK1 | 3.11539298 |
| 7 | TESK2 | 3.04476869 |
| 8 | MAPKAPK3 | 2.84198726 |
| 9 | NME2 | 2.75591066 |
| 10 | PIM2 | 2.63621085 |
| 11 | KDR | 2.41789965 |
| 12 | BCKDK | 2.38650529 |
| 13 | EIF2AK1 | 2.37762773 |
| 14 | NME1 | 2.13362819 |
| 15 | MAP4K1 | 1.96856750 |
| 16 | VRK1 | 1.91553834 |
| 17 | EIF2AK3 | 1.84781920 |
| 18 | ZAK | 1.71138195 |
| 19 | TLK1 | 1.62255181 |
| 20 | MAP4K2 | 1.61518756 |
| 21 | BMPR1B | 1.56557777 |
| 22 | TAOK3 | 1.47919588 |
| 23 | DAPK1 | 1.40573182 |
| 24 | TEC | 1.38669489 |
| 25 | SRPK1 | 1.37484371 |
| 26 | ARAF | 1.36862314 |
| 27 | BUB1 | 1.34911708 |
| 28 | CDC7 | 1.34622365 |
| 29 | RPS6KB2 | 1.31430397 |
| 30 | BTK | 1.25197845 |
| 31 | PBK | 1.20076616 |
| 32 | TESK1 | 1.18524733 |
| 33 | CDK19 | 1.14695480 |
| 34 | KIT | 1.12551380 |
| 35 | ILK | 1.12437138 |
| 36 | LRRK2 | 1.10020133 |
| 37 | TBK1 | 1.06928200 |
| 38 | DAPK3 | 1.03149013 |
| 39 | PIK3CA | 0.96656257 |
| 40 | WEE1 | 0.96217100 |
| 41 | BMPR2 | 0.91510071 |
| 42 | PLK4 | 0.90811466 |
| 43 | CSNK1G3 | 0.88961004 |
| 44 | IKBKB | 0.88095297 |
| 45 | AURKA | 0.83269938 |
| 46 | EIF2AK2 | 0.82869935 |
| 47 | TAOK2 | 0.82609678 |
| 48 | ITK | 0.80852191 |
| 49 | DYRK2 | 0.75270494 |
| 50 | PRKCQ | 0.74348365 |
| 51 | SYK | 0.73561194 |
| 52 | TXK | 0.73413482 |
| 53 | LIMK1 | 0.73038805 |
| 54 | RAF1 | 0.71911711 |
| 55 | LYN | 0.71756358 |
| 56 | RPS6KA5 | 0.70894277 |
| 57 | CSF1R | 0.67831543 |
| 58 | CSNK1G2 | 0.63682599 |
| 59 | AURKB | 0.60479492 |
| 60 | FLT3 | 0.60264225 |
| 61 | ATR | 0.59258129 |
| 62 | STK4 | 0.58571825 |
| 63 | CDK9 | 0.58506305 |
| 64 | PLK1 | 0.58346042 |
| 65 | JAK3 | 0.57510366 |
| 66 | CDK7 | 0.56301082 |
| 67 | CSNK1G1 | 0.54041053 |
| 68 | PAK1 | 0.53713057 |
| 69 | PINK1 | 0.53436382 |
| 70 | CDK8 | 0.53195854 |
| 71 | LCK | 0.52110569 |
| 72 | TGFBR1 | 0.50957239 |
| 73 | LMTK2 | 0.50717306 |
| 74 | CSNK1A1L | 0.49587242 |
| 75 | TAF1 | 0.49182107 |
| 76 | MAPKAPK5 | 0.49175608 |
| 77 | CSNK2A1 | 0.48561663 |
| 78 | CSNK2A2 | 0.46637191 |
| 79 | ABL1 | 0.46360774 |
| 80 | HIPK2 | 0.45512010 |
| 81 | INSRR | 0.44994330 |
| 82 | PASK | 0.40962746 |
| 83 | BRAF | 0.40033878 |
| 84 | EPHB2 | 0.39873244 |
| 85 | MUSK | 0.38644666 |
| 86 | DMPK | 0.37710211 |
| 87 | MATK | 0.37364170 |
| 88 | BRSK2 | 0.35938549 |
| 89 | GRK1 | 0.35563943 |
| 90 | ADRBK2 | 0.35471065 |
| 91 | PRKG2 | 0.35020579 |
| 92 | GRK5 | 0.33770459 |
| 93 | MAP3K14 | 0.33724252 |
| 94 | INSR | 0.33541159 |
| 95 | NEK1 | 0.32312512 |
| 96 | FRK | 0.31473807 |
| 97 | IKBKE | 0.30733857 |
| 98 | CHEK2 | 0.30307911 |
| 99 | MAPK3 | 0.27114475 |
| 100 | MAP2K6 | 0.25993438 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.08362484 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.05820591 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.36057264 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.99634876 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.78917147 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.55188839 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.39819380 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.33091017 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.30768507 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.18135114 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13534446 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.11086994 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.01451259 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.00372135 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 2.00208780 |
| 16 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.95316241 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.94202920 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.93796922 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.82953436 |
| 20 | Base excision repair_Homo sapiens_hsa03410 | 1.76973744 |
| 21 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.63668871 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.59659950 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.59439425 |
| 24 | Homologous recombination_Homo sapiens_hsa03440 | 1.59301143 |
| 25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.56761775 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.56531911 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.54781675 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.45745934 |
| 29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.43085643 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41902380 |
| 31 | Spliceosome_Homo sapiens_hsa03040 | 1.35214154 |
| 32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.30912433 |
| 33 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.29132049 |
| 34 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.27558233 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.26856088 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.24044384 |
| 37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23627115 |
| 38 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.18832286 |
| 39 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.18625302 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.11717588 |
| 41 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.07211566 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.07176873 |
| 43 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.06396555 |
| 44 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.04259414 |
| 45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.03041772 |
| 46 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.02077993 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00707931 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.98601403 |
| 49 | Carbon metabolism_Homo sapiens_hsa01200 | 0.97767687 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.96030152 |
| 51 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.92797001 |
| 52 | Basal transcription factors_Homo sapiens_hsa03022 | 0.92751566 |
| 53 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.91667315 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88415122 |
| 55 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.86756109 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.86206260 |
| 57 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.81332312 |
| 58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.81129391 |
| 59 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.79258365 |
| 60 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.77859644 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.71837431 |
| 62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.70004234 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.69836577 |
| 64 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.68650766 |
| 65 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.67242057 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65779989 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65548185 |
| 68 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.64773022 |
| 69 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.62522263 |
| 70 | Leishmaniasis_Homo sapiens_hsa05140 | 0.61835780 |
| 71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.59061658 |
| 72 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.57278135 |
| 73 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.52870929 |
| 74 | Shigellosis_Homo sapiens_hsa05131 | 0.51914522 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51833796 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.51767915 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.47332530 |
| 78 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.46925045 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45639964 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.45608806 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.44687423 |
| 82 | Cell cycle_Homo sapiens_hsa04110 | 0.42585143 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40206018 |
| 84 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.39717855 |
| 85 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.39074590 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36722877 |
| 87 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.35830095 |
| 88 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34980146 |
| 89 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34957635 |
| 90 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.34073298 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33007702 |
| 92 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.32855456 |
| 93 | Alcoholism_Homo sapiens_hsa05034 | 0.31409676 |
| 94 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.29640971 |
| 95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28611437 |
| 96 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26540323 |
| 97 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26426139 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.25537164 |
| 99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.22707226 |
| 100 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.22533643 |

