

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein complex biogenesis (GO:0070271) | 5.02384545 |
| 2 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.71330035 |
| 3 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.71330035 |
| 4 | NADH dehydrogenase complex assembly (GO:0010257) | 4.71330035 |
| 5 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.70247264 |
| 6 | DNA deamination (GO:0045006) | 4.63257061 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.53282875 |
| 8 | respiratory chain complex IV assembly (GO:0008535) | 4.45811499 |
| 9 | rRNA modification (GO:0000154) | 4.27577159 |
| 10 | mismatch repair (GO:0006298) | 4.24926123 |
| 11 | cytochrome complex assembly (GO:0017004) | 4.16158126 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.07244658 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.07093621 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 4.07093621 |
| 15 | protein deneddylation (GO:0000338) | 4.05663136 |
| 16 | cullin deneddylation (GO:0010388) | 3.98842813 |
| 17 | rRNA methylation (GO:0031167) | 3.84513856 |
| 18 | mannosylation (GO:0097502) | 3.81251179 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.70615164 |
| 20 | regulation of mitochondrial translation (GO:0070129) | 3.69620555 |
| 21 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.64941294 |
| 22 | chaperone-mediated protein transport (GO:0072321) | 3.63141219 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.55614743 |
| 24 | respiratory electron transport chain (GO:0022904) | 3.53341622 |
| 25 | maturation of 5.8S rRNA (GO:0000460) | 3.50265179 |
| 26 | electron transport chain (GO:0022900) | 3.50155410 |
| 27 | DNA double-strand break processing (GO:0000729) | 3.49044490 |
| 28 | protein localization to kinetochore (GO:0034501) | 3.47158177 |
| 29 | pseudouridine synthesis (GO:0001522) | 3.38068393 |
| 30 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.36006745 |
| 31 | adenosine metabolic process (GO:0046085) | 3.34544366 |
| 32 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.32563575 |
| 33 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.29384525 |
| 34 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.25984594 |
| 35 | base-excision repair, AP site formation (GO:0006285) | 3.21047615 |
| 36 | DNA ligation (GO:0006266) | 3.19068325 |
| 37 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.17017879 |
| 38 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.16711832 |
| 39 | platelet dense granule organization (GO:0060155) | 3.15691413 |
| 40 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.14310187 |
| 41 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.14310187 |
| 42 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.14310187 |
| 43 | peptidyl-histidine modification (GO:0018202) | 3.12611911 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.12428709 |
| 45 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.12428709 |
| 46 | negative regulation of telomere maintenance (GO:0032205) | 3.08861313 |
| 47 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.08563360 |
| 48 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.07659841 |
| 49 | protein-cofactor linkage (GO:0018065) | 3.07324965 |
| 50 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.06567585 |
| 51 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.06567585 |
| 52 | GPI anchor biosynthetic process (GO:0006506) | 3.03996761 |
| 53 | inner mitochondrial membrane organization (GO:0007007) | 3.01060163 |
| 54 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.00126285 |
| 55 | GPI anchor metabolic process (GO:0006505) | 2.97046939 |
| 56 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.97044527 |
| 57 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.97044527 |
| 58 | tRNA processing (GO:0008033) | 2.96890072 |
| 59 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.96810467 |
| 60 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.96810467 |
| 61 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.96296787 |
| 62 | tRNA modification (GO:0006400) | 2.93969267 |
| 63 | negative regulation of ligase activity (GO:0051352) | 2.92076799 |
| 64 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.92076799 |
| 65 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.91509549 |
| 66 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.91509549 |
| 67 | behavioral response to nicotine (GO:0035095) | 2.91099382 |
| 68 | ubiquinone biosynthetic process (GO:0006744) | 2.88263914 |
| 69 | sequestering of actin monomers (GO:0042989) | 2.88151457 |
| 70 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.87518235 |
| 71 | L-fucose catabolic process (GO:0042355) | 2.86895862 |
| 72 | fucose catabolic process (GO:0019317) | 2.86895862 |
| 73 | L-fucose metabolic process (GO:0042354) | 2.86895862 |
| 74 | proteasome assembly (GO:0043248) | 2.86690604 |
| 75 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.86378355 |
| 76 | ribosomal small subunit assembly (GO:0000028) | 2.86103235 |
| 77 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.83085272 |
| 78 | positive regulation of prostaglandin secretion (GO:0032308) | 2.81724635 |
| 79 | C-terminal protein lipidation (GO:0006501) | 2.80944987 |
| 80 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.80090655 |
| 81 | termination of RNA polymerase III transcription (GO:0006386) | 2.80090655 |
| 82 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.77666546 |
| 83 | GTP biosynthetic process (GO:0006183) | 2.75624095 |
| 84 | mitochondrial RNA metabolic process (GO:0000959) | 2.75196682 |
| 85 | histone H2A acetylation (GO:0043968) | 2.75005114 |
| 86 | protein prenylation (GO:0018342) | 2.72487017 |
| 87 | prenylation (GO:0097354) | 2.72487017 |
| 88 | ribosomal large subunit biogenesis (GO:0042273) | 2.70448709 |
| 89 | replication fork processing (GO:0031297) | 2.69522532 |
| 90 | regulation of helicase activity (GO:0051095) | 2.66879780 |
| 91 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.66426921 |
| 92 | ubiquinone metabolic process (GO:0006743) | 2.65300229 |
| 93 | tRNA metabolic process (GO:0006399) | 2.64898034 |
| 94 | spliceosomal snRNP assembly (GO:0000387) | 2.64316690 |
| 95 | DNA damage response, detection of DNA damage (GO:0042769) | 2.64055229 |
| 96 | amino acid salvage (GO:0043102) | 2.63507110 |
| 97 | L-methionine salvage (GO:0071267) | 2.63507110 |
| 98 | L-methionine biosynthetic process (GO:0071265) | 2.63507110 |
| 99 | positive regulation of ligase activity (GO:0051351) | 2.62708484 |
| 100 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.60789815 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.12698705 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.54403020 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.18526206 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.92190699 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.63268064 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.40638839 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.34914706 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.24793378 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.12930969 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.94260132 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.90570445 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.78395965 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.60064311 |
| 14 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.58463753 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.55011528 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.47474143 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.43478257 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.26621468 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.08673075 |
| 20 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.07691173 |
| 21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.06403502 |
| 22 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.98643490 |
| 23 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.94343648 |
| 24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.83382530 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81435710 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.81391264 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.78157544 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.77668594 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.74722991 |
| 30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.73739269 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65943296 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.64320447 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.63616974 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.62289591 |
| 35 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.61282217 |
| 36 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.60055896 |
| 37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.57478868 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.56300090 |
| 39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.55797206 |
| 40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.52231650 |
| 41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51878461 |
| 42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.49589674 |
| 43 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.49283065 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.46640594 |
| 45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.42812234 |
| 46 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.42524715 |
| 47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.42380317 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.39128735 |
| 49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.34966050 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.32445751 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32278528 |
| 52 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.32025993 |
| 53 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.31919051 |
| 54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31790460 |
| 55 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26741517 |
| 56 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.20315605 |
| 57 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19701099 |
| 58 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17786509 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17220749 |
| 60 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.16760942 |
| 61 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.12570864 |
| 62 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.11924064 |
| 63 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11458454 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10427434 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10043106 |
| 66 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10043106 |
| 67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.08065346 |
| 68 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.07942501 |
| 69 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.07454242 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06575985 |
| 71 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.05708434 |
| 72 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.05239475 |
| 73 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04901700 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03363963 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.02802967 |
| 76 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.01928524 |
| 77 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.01068544 |
| 78 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.00372045 |
| 79 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.94898287 |
| 80 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.94769266 |
| 81 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.93168085 |
| 82 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92164515 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91650227 |
| 84 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91650227 |
| 85 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.90712269 |
| 86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89531721 |
| 87 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.88942297 |
| 88 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.87464741 |
| 89 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.86756742 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86756742 |
| 91 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86378160 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86065681 |
| 93 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.85970905 |
| 94 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84485054 |
| 95 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.84063068 |
| 96 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.81279802 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.80850760 |
| 98 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.80644159 |
| 99 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.79882015 |
| 100 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.79164939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.52108420 |
| 2 | MP0001529_abnormal_vocalization | 2.81929846 |
| 3 | MP0002736_abnormal_nociception_after | 2.74947568 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.70000919 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.68394460 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.47025110 |
| 7 | MP0004147_increased_porphyrin_level | 2.34228101 |
| 8 | MP0003786_premature_aging | 2.27686393 |
| 9 | MP0005075_abnormal_melanosome_morpholog | 2.23001298 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.21172186 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.16702869 |
| 12 | MP0010094_abnormal_chromosome_stability | 2.15010383 |
| 13 | MP0003718_maternal_effect | 2.08584538 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 2.08018831 |
| 15 | MP0002938_white_spotting | 2.00062558 |
| 16 | MP0003011_delayed_dark_adaptation | 1.99595892 |
| 17 | MP0008995_early_reproductive_senescence | 1.95407190 |
| 18 | MP0003195_calcinosis | 1.94043107 |
| 19 | MP0005646_abnormal_pituitary_gland | 1.88752123 |
| 20 | MP0009697_abnormal_copulation | 1.87536319 |
| 21 | MP0006036_abnormal_mitochondrial_physio | 1.84308335 |
| 22 | MP0003787_abnormal_imprinting | 1.82732927 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.80649590 |
| 24 | MP0003880_abnormal_central_pattern | 1.76913773 |
| 25 | MP0005253_abnormal_eye_physiology | 1.76619705 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.74723382 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.72688859 |
| 28 | MP0003693_abnormal_embryo_hatching | 1.70598718 |
| 29 | MP0002653_abnormal_ependyma_morphology | 1.69081973 |
| 30 | MP0001905_abnormal_dopamine_level | 1.66042168 |
| 31 | MP0002102_abnormal_ear_morphology | 1.58332585 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.54464322 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.54320633 |
| 34 | MP0008872_abnormal_physiological_respon | 1.53654039 |
| 35 | MP0006292_abnormal_olfactory_placode | 1.51061624 |
| 36 | MP0004142_abnormal_muscle_tone | 1.43966915 |
| 37 | MP0003186_abnormal_redox_activity | 1.42139262 |
| 38 | MP0001764_abnormal_homeostasis | 1.41657578 |
| 39 | MP0001501_abnormal_sleep_pattern | 1.41390856 |
| 40 | MP0003111_abnormal_nucleus_morphology | 1.41324337 |
| 41 | MP0002876_abnormal_thyroid_physiology | 1.37936178 |
| 42 | MP0003806_abnormal_nucleotide_metabolis | 1.30366169 |
| 43 | MP0003121_genomic_imprinting | 1.29375686 |
| 44 | MP0000569_abnormal_digit_pigmentation | 1.25789903 |
| 45 | MP0002837_dystrophic_cardiac_calcinosis | 1.23772881 |
| 46 | MP0004133_heterotaxia | 1.23723054 |
| 47 | MP0004145_abnormal_muscle_electrophysio | 1.21982899 |
| 48 | MP0001984_abnormal_olfaction | 1.19845106 |
| 49 | MP0008789_abnormal_olfactory_epithelium | 1.18353049 |
| 50 | MP0002822_catalepsy | 1.14197465 |
| 51 | MP0009046_muscle_twitch | 1.12089660 |
| 52 | MP0002272_abnormal_nervous_system | 1.10128309 |
| 53 | MP0000631_abnormal_neuroendocrine_gland | 1.09981318 |
| 54 | MP0004957_abnormal_blastocyst_morpholog | 1.06700498 |
| 55 | MP0002735_abnormal_chemical_nociception | 1.05765087 |
| 56 | MP0003077_abnormal_cell_cycle | 1.05080042 |
| 57 | MP0002234_abnormal_pharynx_morphology | 1.05048583 |
| 58 | MP0009745_abnormal_behavioral_response | 1.04652878 |
| 59 | MP0010386_abnormal_urinary_bladder | 0.98627043 |
| 60 | MP0008775_abnormal_heart_ventricle | 0.95094798 |
| 61 | MP0001486_abnormal_startle_reflex | 0.94633145 |
| 62 | MP0005174_abnormal_tail_pigmentation | 0.94567827 |
| 63 | MP0002751_abnormal_autonomic_nervous | 0.94173094 |
| 64 | MP0002095_abnormal_skin_pigmentation | 0.93432376 |
| 65 | MP0002148_abnormal_hypersensitivity_rea | 0.90869580 |
| 66 | MP0001929_abnormal_gametogenesis | 0.90448780 |
| 67 | MP0002557_abnormal_social/conspecific_i | 0.89927430 |
| 68 | MP0005499_abnormal_olfactory_system | 0.89562433 |
| 69 | MP0005394_taste/olfaction_phenotype | 0.89562433 |
| 70 | MP0008007_abnormal_cellular_replicative | 0.88885776 |
| 71 | MP0005671_abnormal_response_to | 0.88605648 |
| 72 | MP0004885_abnormal_endolymph | 0.88337524 |
| 73 | MP0008932_abnormal_embryonic_tissue | 0.87791331 |
| 74 | MP0002733_abnormal_thermal_nociception | 0.86983861 |
| 75 | MP0002928_abnormal_bile_duct | 0.81417750 |
| 76 | MP0000358_abnormal_cell_content/ | 0.80678418 |
| 77 | MP0000689_abnormal_spleen_morphology | 0.77314041 |
| 78 | MP0004742_abnormal_vestibular_system | 0.77219040 |
| 79 | MP0002572_abnormal_emotion/affect_behav | 0.76444787 |
| 80 | MP0001919_abnormal_reproductive_system | 0.76108108 |
| 81 | MP0001119_abnormal_female_reproductive | 0.74862513 |
| 82 | MP0000516_abnormal_urinary_system | 0.74052126 |
| 83 | MP0005367_renal/urinary_system_phenotyp | 0.74052126 |
| 84 | MP0000465_gastrointestinal_hemorrhage | 0.73231956 |
| 85 | MP0002277_abnormal_respiratory_mucosa | 0.72930552 |
| 86 | MP0002019_abnormal_tumor_incidence | 0.72709205 |
| 87 | MP0002210_abnormal_sex_determination | 0.71480221 |
| 88 | MP0005423_abnormal_somatic_nervous | 0.71299470 |
| 89 | MP0005389_reproductive_system_phenotype | 0.70353409 |
| 90 | MP0005395_other_phenotype | 0.70154009 |
| 91 | MP0003698_abnormal_male_reproductive | 0.70151646 |
| 92 | MP0001293_anophthalmia | 0.69265217 |
| 93 | MP0000653_abnormal_sex_gland | 0.68617791 |
| 94 | MP0003136_yellow_coat_color | 0.67815940 |
| 95 | MP0005266_abnormal_metabolism | 0.67639229 |
| 96 | MP0001145_abnormal_male_reproductive | 0.67481013 |
| 97 | MP0005332_abnormal_amino_acid | 0.66554365 |
| 98 | MP0002282_abnormal_trachea_morphology | 0.66232204 |
| 99 | MP0005410_abnormal_fertilization | 0.64993631 |
| 100 | MP0006054_spinal_hemorrhage | 0.64140233 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.71352669 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.59391038 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.33277166 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.19821552 |
| 5 | Acute encephalopathy (HP:0006846) | 4.14963209 |
| 6 | Increased CSF lactate (HP:0002490) | 4.14418201 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 4.02492983 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.99927453 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.91647172 |
| 10 | Hepatic necrosis (HP:0002605) | 3.82825038 |
| 11 | Renal Fanconi syndrome (HP:0001994) | 3.66242033 |
| 12 | Pancreatic cysts (HP:0001737) | 3.21022948 |
| 13 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.17497799 |
| 14 | Pancreatic fibrosis (HP:0100732) | 3.16199134 |
| 15 | Cerebral edema (HP:0002181) | 3.10404775 |
| 16 | Type I transferrin isoform profile (HP:0003642) | 3.09941229 |
| 17 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.04381015 |
| 18 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.04381015 |
| 19 | Abnormal protein glycosylation (HP:0012346) | 3.04381015 |
| 20 | Abnormal glycosylation (HP:0012345) | 3.04381015 |
| 21 | Microvesicular hepatic steatosis (HP:0001414) | 2.98946623 |
| 22 | Increased intramyocellular lipid droplets (HP:0012240) | 2.88695206 |
| 23 | Renal cortical cysts (HP:0000803) | 2.85580903 |
| 24 | Degeneration of anterior horn cells (HP:0002398) | 2.80978446 |
| 25 | Abnormality of the anterior horn cell (HP:0006802) | 2.80978446 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.79980719 |
| 27 | Increased serum lactate (HP:0002151) | 2.77557183 |
| 28 | True hermaphroditism (HP:0010459) | 2.74583455 |
| 29 | Medial flaring of the eyebrow (HP:0010747) | 2.73403425 |
| 30 | Lactic acidosis (HP:0003128) | 2.69635302 |
| 31 | Nephronophthisis (HP:0000090) | 2.64312311 |
| 32 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.62938205 |
| 33 | Methylmalonic acidemia (HP:0002912) | 2.61687653 |
| 34 | Abnormal number of erythroid precursors (HP:0012131) | 2.61094302 |
| 35 | Colon cancer (HP:0003003) | 2.59645585 |
| 36 | Exercise intolerance (HP:0003546) | 2.56721397 |
| 37 | Optic disc pallor (HP:0000543) | 2.54385412 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.52685784 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 2.52685784 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.48834269 |
| 41 | Exertional dyspnea (HP:0002875) | 2.47212079 |
| 42 | Abnormality of the renal cortex (HP:0011035) | 2.46319865 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.45612264 |
| 44 | Severe combined immunodeficiency (HP:0004430) | 2.38793530 |
| 45 | Respiratory failure (HP:0002878) | 2.34779375 |
| 46 | Methylmalonic aciduria (HP:0012120) | 2.30157287 |
| 47 | Type II lissencephaly (HP:0007260) | 2.29242813 |
| 48 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.29087985 |
| 49 | Decreased central vision (HP:0007663) | 2.28413324 |
| 50 | Abnormality of renal resorption (HP:0011038) | 2.28399343 |
| 51 | Bile duct proliferation (HP:0001408) | 2.24509237 |
| 52 | Abnormal biliary tract physiology (HP:0012439) | 2.24509237 |
| 53 | Congenital, generalized hypertrichosis (HP:0004540) | 2.23934815 |
| 54 | Attenuation of retinal blood vessels (HP:0007843) | 2.22475474 |
| 55 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.21619547 |
| 56 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.21619547 |
| 57 | Dicarboxylic aciduria (HP:0003215) | 2.18121990 |
| 58 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.18121990 |
| 59 | Aplastic anemia (HP:0001915) | 2.15114947 |
| 60 | Lethargy (HP:0001254) | 2.13419518 |
| 61 | Abnormality of the renal medulla (HP:0100957) | 2.13414652 |
| 62 | Cerebellar dysplasia (HP:0007033) | 2.10545112 |
| 63 | Abnormality of methionine metabolism (HP:0010901) | 2.08609639 |
| 64 | Congenital primary aphakia (HP:0007707) | 2.05382173 |
| 65 | Gait imbalance (HP:0002141) | 2.05073068 |
| 66 | Retinal dysplasia (HP:0007973) | 2.04493758 |
| 67 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.03143475 |
| 68 | Abnormality of lateral ventricle (HP:0030047) | 2.02724507 |
| 69 | Pancytopenia (HP:0001876) | 1.99762608 |
| 70 | Glycosuria (HP:0003076) | 1.99360244 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.99360244 |
| 72 | Oral leukoplakia (HP:0002745) | 1.96920856 |
| 73 | Abnormality of the pons (HP:0007361) | 1.94679679 |
| 74 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.94231368 |
| 75 | Panhypogammaglobulinemia (HP:0003139) | 1.93920837 |
| 76 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.92933875 |
| 77 | Hypoplasia of the pons (HP:0012110) | 1.92616189 |
| 78 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91557600 |
| 79 | IgG deficiency (HP:0004315) | 1.90935137 |
| 80 | Pendular nystagmus (HP:0012043) | 1.90903999 |
| 81 | Congenital stationary night blindness (HP:0007642) | 1.90676446 |
| 82 | Hypothermia (HP:0002045) | 1.89958757 |
| 83 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88398949 |
| 84 | Progressive microcephaly (HP:0000253) | 1.87605340 |
| 85 | Leukodystrophy (HP:0002415) | 1.86691771 |
| 86 | CNS demyelination (HP:0007305) | 1.85991293 |
| 87 | Abnormality of the prostate (HP:0008775) | 1.85947864 |
| 88 | Generalized aminoaciduria (HP:0002909) | 1.82734593 |
| 89 | Combined immunodeficiency (HP:0005387) | 1.82243440 |
| 90 | Sclerocornea (HP:0000647) | 1.81442463 |
| 91 | Stomach cancer (HP:0012126) | 1.81310511 |
| 92 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.76686560 |
| 93 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.75066058 |
| 94 | Male pseudohermaphroditism (HP:0000037) | 1.75042933 |
| 95 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.71254803 |
| 96 | Prostate neoplasm (HP:0100787) | 1.70708739 |
| 97 | Respiratory difficulties (HP:0002880) | 1.70384912 |
| 98 | Emotional lability (HP:0000712) | 1.70276946 |
| 99 | Cystic liver disease (HP:0006706) | 1.69755435 |
| 100 | Hyperglycinuria (HP:0003108) | 1.69429163 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.79623094 |
| 2 | NUAK1 | 3.58527611 |
| 3 | TAOK3 | 3.25341244 |
| 4 | ZAK | 3.22211277 |
| 5 | MAP4K2 | 3.16475406 |
| 6 | STK16 | 2.62993502 |
| 7 | WNK3 | 2.56673282 |
| 8 | VRK1 | 2.28700546 |
| 9 | TAF1 | 2.13988346 |
| 10 | BUB1 | 1.97142882 |
| 11 | MST4 | 1.93247003 |
| 12 | CDC7 | 1.81751928 |
| 13 | CCNB1 | 1.70760091 |
| 14 | FRK | 1.69071170 |
| 15 | TLK1 | 1.69051904 |
| 16 | EIF2AK3 | 1.68675496 |
| 17 | SRPK1 | 1.65022308 |
| 18 | BCKDK | 1.56959507 |
| 19 | BMPR1B | 1.56571304 |
| 20 | PBK | 1.51979027 |
| 21 | TNIK | 1.45715813 |
| 22 | INSRR | 1.39112920 |
| 23 | PLK3 | 1.32498066 |
| 24 | TESK2 | 1.32355540 |
| 25 | MAP3K4 | 1.28027500 |
| 26 | NME1 | 1.25780095 |
| 27 | MAP3K12 | 1.24085642 |
| 28 | GRK1 | 1.20732419 |
| 29 | EIF2AK2 | 1.18399206 |
| 30 | TRIM28 | 1.18324515 |
| 31 | MAPK13 | 1.16987992 |
| 32 | ADRBK2 | 1.14964670 |
| 33 | CSNK1G3 | 1.14025942 |
| 34 | DYRK2 | 1.13404052 |
| 35 | BRSK2 | 1.10199496 |
| 36 | TXK | 1.02418375 |
| 37 | KIT | 0.98327964 |
| 38 | MAP2K7 | 0.96626626 |
| 39 | IKBKB | 0.96449582 |
| 40 | MKNK1 | 0.96012315 |
| 41 | CSNK1G1 | 0.93566295 |
| 42 | CSNK1G2 | 0.92740027 |
| 43 | FLT3 | 0.91151595 |
| 44 | TEC | 0.90774965 |
| 45 | DAPK1 | 0.87966222 |
| 46 | ATR | 0.87691784 |
| 47 | ERBB3 | 0.85753243 |
| 48 | MKNK2 | 0.85716194 |
| 49 | NEK1 | 0.83779009 |
| 50 | TTK | 0.82344659 |
| 51 | PDK2 | 0.80659855 |
| 52 | PINK1 | 0.78091421 |
| 53 | CSNK1A1L | 0.76297997 |
| 54 | PLK4 | 0.76284809 |
| 55 | WEE1 | 0.74204485 |
| 56 | TIE1 | 0.74171630 |
| 57 | EIF2AK1 | 0.74043755 |
| 58 | PLK2 | 0.73552798 |
| 59 | GRK6 | 0.67024598 |
| 60 | PLK1 | 0.66305281 |
| 61 | IRAK1 | 0.64986302 |
| 62 | PHKG2 | 0.64682685 |
| 63 | PHKG1 | 0.64682685 |
| 64 | DYRK3 | 0.61036179 |
| 65 | BCR | 0.60959043 |
| 66 | KDR | 0.60778243 |
| 67 | TSSK6 | 0.60307572 |
| 68 | MAP2K2 | 0.59798632 |
| 69 | CHEK2 | 0.58927614 |
| 70 | SYK | 0.58782658 |
| 71 | RPS6KA5 | 0.57555446 |
| 72 | CSF1R | 0.56898910 |
| 73 | CDK8 | 0.56830266 |
| 74 | MAPKAPK3 | 0.56327626 |
| 75 | CASK | 0.54190287 |
| 76 | PRKCQ | 0.52755278 |
| 77 | MAPKAPK5 | 0.51667780 |
| 78 | PAK3 | 0.51326535 |
| 79 | MAP4K1 | 0.50425453 |
| 80 | AURKB | 0.50409484 |
| 81 | PIM2 | 0.50323152 |
| 82 | IKBKE | 0.47447610 |
| 83 | PRKCG | 0.45517980 |
| 84 | MUSK | 0.44881857 |
| 85 | PKN1 | 0.44596533 |
| 86 | LIMK1 | 0.44095521 |
| 87 | LYN | 0.43987739 |
| 88 | PRKCE | 0.43287026 |
| 89 | MAP3K14 | 0.41729039 |
| 90 | FES | 0.41724393 |
| 91 | ITK | 0.40359020 |
| 92 | MARK1 | 0.40045556 |
| 93 | TBK1 | 0.39666160 |
| 94 | OXSR1 | 0.39367689 |
| 95 | CSNK2A1 | 0.38654376 |
| 96 | CSNK2A2 | 0.36601577 |
| 97 | ATM | 0.35383484 |
| 98 | AURKA | 0.34783569 |
| 99 | RPS6KA4 | 0.34685892 |
| 100 | MAP3K5 | 0.32981771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.96104800 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.52341086 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.50034097 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.07068436 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.71573312 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.33416085 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.30657720 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.26936209 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.15565581 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.11779636 |
| 11 | Base excision repair_Homo sapiens_hsa03410 | 2.10845581 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.04373123 |
| 13 | DNA replication_Homo sapiens_hsa03030 | 2.00807140 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.99132951 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.96002698 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.87902509 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.85422506 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82724378 |
| 19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.81177043 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.76067686 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.74119233 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.70128424 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.68679183 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.60324537 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.57740638 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55869145 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.54265172 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.47301617 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.40872781 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.36397342 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.35295543 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.31788184 |
| 33 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.30888002 |
| 34 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29137790 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.29073253 |
| 36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.28011160 |
| 37 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.19464549 |
| 38 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.17749399 |
| 39 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.17362478 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.16219416 |
| 41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.14374726 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10788691 |
| 43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.09668753 |
| 44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.09522534 |
| 45 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.05760513 |
| 46 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.03973218 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.03191180 |
| 48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99172417 |
| 49 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97587992 |
| 50 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.83840864 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83606478 |
| 52 | Metabolic pathways_Homo sapiens_hsa01100 | 0.83135053 |
| 53 | Nicotine addiction_Homo sapiens_hsa05033 | 0.80426015 |
| 54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.80421945 |
| 55 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.79481236 |
| 56 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.79425602 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.78456730 |
| 58 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.75088031 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74671962 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74412822 |
| 61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.74370307 |
| 62 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.71127882 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70956320 |
| 64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65669546 |
| 65 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.63728546 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.63516364 |
| 67 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.62417406 |
| 68 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.61861166 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.61015765 |
| 70 | Taste transduction_Homo sapiens_hsa04742 | 0.60406844 |
| 71 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55633524 |
| 72 | Asthma_Homo sapiens_hsa05310 | 0.53249520 |
| 73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.52960257 |
| 74 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.51678049 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51478270 |
| 76 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.50953482 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49811476 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49700139 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.49433819 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46138158 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45624144 |
| 82 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43097325 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42866345 |
| 84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.40184908 |
| 85 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38608341 |
| 86 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.38474725 |
| 87 | Cell cycle_Homo sapiens_hsa04110 | 0.37046905 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35891717 |
| 89 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.31256006 |
| 90 | Allograft rejection_Homo sapiens_hsa05330 | 0.31060617 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.31011229 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.30603935 |
| 93 | Carbon metabolism_Homo sapiens_hsa01200 | 0.27527762 |
| 94 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.27155557 |
| 95 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.27047489 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.26275423 |
| 97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.25021977 |
| 98 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.24248716 |
| 99 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.23506012 |
| 100 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.22077268 |

