PNCK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)5.74814861
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.60965333
3neuron cell-cell adhesion (GO:0007158)5.42839950
4synaptic vesicle exocytosis (GO:0016079)5.39878405
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.11500858
6cellular potassium ion homeostasis (GO:0030007)5.01406532
7regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.94349280
8regulation of glutamate receptor signaling pathway (GO:1900449)4.87576788
9protein localization to synapse (GO:0035418)4.76834153
10sodium ion export (GO:0071436)4.70026730
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.67021499
12regulation of synaptic vesicle exocytosis (GO:2000300)4.60006369
13glutamate secretion (GO:0014047)4.55506967
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.52650039
15synaptic vesicle maturation (GO:0016188)4.44453940
16neurotransmitter secretion (GO:0007269)4.37246666
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.30602263
18L-amino acid import (GO:0043092)4.29721502
19gamma-aminobutyric acid signaling pathway (GO:0007214)4.19116862
20postsynaptic membrane organization (GO:0001941)4.18708899
21synaptic vesicle docking involved in exocytosis (GO:0016081)4.12648535
22neurotransmitter-gated ion channel clustering (GO:0072578)4.12425005
23presynaptic membrane assembly (GO:0097105)4.12343339
24glutamate receptor signaling pathway (GO:0007215)4.12211108
25axon ensheathment in central nervous system (GO:0032291)4.10630279
26central nervous system myelination (GO:0022010)4.10630279
27neuron-neuron synaptic transmission (GO:0007270)4.10112793
28synaptic transmission, glutamatergic (GO:0035249)4.09972179
29locomotory exploration behavior (GO:0035641)4.08044988
30response to histamine (GO:0034776)4.06883942
31regulation of synaptic vesicle transport (GO:1902803)4.06707734
32neuronal ion channel clustering (GO:0045161)3.96825249
33positive regulation of dendritic spine development (GO:0060999)3.95918935
34neuronal action potential propagation (GO:0019227)3.94159520
35neuron recognition (GO:0008038)3.91226248
36cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.90694630
37positive regulation of synaptic transmission, GABAergic (GO:0032230)3.89664772
38positive regulation of synapse assembly (GO:0051965)3.87537932
39amino acid import (GO:0043090)3.87075249
40exploration behavior (GO:0035640)3.79277179
41regulation of synapse maturation (GO:0090128)3.79027774
42regulation of voltage-gated calcium channel activity (GO:1901385)3.77881589
43presynaptic membrane organization (GO:0097090)3.75709382
44neurotransmitter transport (GO:0006836)3.74521161
45negative regulation of synaptic transmission, GABAergic (GO:0032229)3.74334375
46regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.71147998
47regulation of glutamate secretion (GO:0014048)3.71076534
48cell migration in hindbrain (GO:0021535)3.59590658
49neuromuscular process controlling balance (GO:0050885)3.59313529
50potassium ion homeostasis (GO:0055075)3.58547095
51long-term memory (GO:0007616)3.58222702
52regulation of neuronal synaptic plasticity (GO:0048168)3.54806465
53negative regulation of dendrite morphogenesis (GO:0050774)3.53546992
54gamma-aminobutyric acid transport (GO:0015812)3.53519235
55cell communication by electrical coupling (GO:0010644)3.52690155
56cerebellar Purkinje cell differentiation (GO:0021702)3.51144944
57energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.49437536
58ATP hydrolysis coupled proton transport (GO:0015991)3.49437536
59regulation of long-term neuronal synaptic plasticity (GO:0048169)3.46687668
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.46321686
61startle response (GO:0001964)3.45370244
62proline transport (GO:0015824)3.43709798
63positive regulation of neurotransmitter secretion (GO:0001956)3.42653165
64long-term synaptic potentiation (GO:0060291)3.41855131
65regulation of neurotransmitter levels (GO:0001505)3.39214540
66female mating behavior (GO:0060180)3.36819932
67regulation of postsynaptic membrane potential (GO:0060078)3.36544188
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.35546979
69positive regulation of synapse maturation (GO:0090129)3.34959187
70positive regulation of membrane potential (GO:0045838)3.33782627
71transmission of nerve impulse (GO:0019226)3.32888614
72dendritic spine organization (GO:0097061)3.32709317
73regulation of synaptic transmission, glutamatergic (GO:0051966)3.32581751
74G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.32344798
75transferrin transport (GO:0033572)3.31009460
76negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.30236697
77neuromuscular process controlling posture (GO:0050884)3.29821664
78regulation of dendritic spine development (GO:0060998)3.29776921
79potassium ion import (GO:0010107)3.27831991
80regulation of ARF protein signal transduction (GO:0032012)3.27642217
81cellular sodium ion homeostasis (GO:0006883)3.26692311
82regulation of synapse structural plasticity (GO:0051823)3.26441361
83regulation of female receptivity (GO:0045924)3.22753356
84positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.22502269
85synaptic vesicle endocytosis (GO:0048488)3.22179541
86regulation of protein kinase A signaling (GO:0010738)3.20952306
87G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.18905593
88axonal fasciculation (GO:0007413)3.17828592
89regulation of vesicle fusion (GO:0031338)3.17003815
90synapse assembly (GO:0007416)3.15959031
91dendritic spine morphogenesis (GO:0060997)3.15308126
92behavioral fear response (GO:0001662)3.13904340
93behavioral defense response (GO:0002209)3.13904340
94opioid receptor signaling pathway (GO:0038003)3.10095997
95regulation of neurotransmitter secretion (GO:0046928)3.09622343
96neuromuscular synaptic transmission (GO:0007274)3.09346106
97trivalent inorganic cation transport (GO:0072512)3.06723850
98ferric iron transport (GO:0015682)3.06723850
99positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.06704490
100regulation of synaptic transmission, GABAergic (GO:0032228)3.05917306
101membrane depolarization during action potential (GO:0086010)3.05370136
102membrane hyperpolarization (GO:0060081)3.03794087
103layer formation in cerebral cortex (GO:0021819)3.03280312
104positive regulation of dendrite development (GO:1900006)3.03177884
105regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.02610041
106regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.02239762
107synaptic transmission (GO:0007268)3.01418182
108acidic amino acid transport (GO:0015800)3.00336655
109regulation of synaptic transmission (GO:0050804)2.99374646
110regulation of synapse assembly (GO:0051963)2.99009077
111regulation of synaptic plasticity (GO:0048167)2.98226004
112activation of protein kinase A activity (GO:0034199)2.98086288
113learning (GO:0007612)2.97951658
114regulation of dendritic spine morphogenesis (GO:0061001)2.97868092
115cerebellar granule cell differentiation (GO:0021707)2.96108687
116regulation of dendrite morphogenesis (GO:0048814)2.95680932
117fear response (GO:0042596)2.95534379
118auditory behavior (GO:0031223)2.95085141
119positive regulation of synaptic transmission (GO:0050806)2.94524085
120positive regulation of dendritic spine morphogenesis (GO:0061003)2.92752599
121regulation of neurotransmitter transport (GO:0051588)2.92495259
122membrane depolarization (GO:0051899)2.92272962
123cytoskeletal anchoring at plasma membrane (GO:0007016)2.92136032
124positive regulation of neurotransmitter transport (GO:0051590)2.91727052
125synaptic vesicle transport (GO:0048489)2.91690920
126establishment of synaptic vesicle localization (GO:0097480)2.91690920
127establishment of mitochondrion localization (GO:0051654)2.90580543
128positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.90557957
129chemosensory behavior (GO:0007635)2.89221306
130dicarboxylic acid transport (GO:0006835)2.88741520
131adult walking behavior (GO:0007628)2.88079281
132mating behavior (GO:0007617)2.88017977
133striatum development (GO:0021756)2.87765824
134cerebellar Purkinje cell layer development (GO:0021680)2.86891872
135intraspecies interaction between organisms (GO:0051703)2.86686689
136cell communication involved in cardiac conduction (GO:0086065)2.86586196

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.90377156
2GBX2_23144817_ChIP-Seq_PC3_Human4.03774084
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.14711664
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.12109147
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.00563265
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.86570473
7TAF15_26573619_Chip-Seq_HEK293_Human2.77994386
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.71753585
9REST_21632747_ChIP-Seq_MESCs_Mouse2.67928995
10CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.67004798
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.63623936
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.63284215
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.54990535
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.53522039
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.53522039
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51780691
17IKZF1_21737484_ChIP-ChIP_HCT116_Human2.51273604
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.49586390
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.41824985
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.41458462
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.38646440
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.35798769
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.31254499
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.28151682
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.24885970
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23383519
27CTBP1_25329375_ChIP-Seq_LNCAP_Human2.11216657
28RNF2_27304074_Chip-Seq_ESCs_Mouse2.09991602
29RARB_27405468_Chip-Seq_BRAIN_Mouse2.08850725
30* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.97064432
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.96743854
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.95957271
33DROSHA_22980978_ChIP-Seq_HELA_Human1.92291173
34SMAD4_21799915_ChIP-Seq_A2780_Human1.82336822
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.79722913
36KDM2B_26808549_Chip-Seq_K562_Human1.76033194
37P300_19829295_ChIP-Seq_ESCs_Human1.72727653
38VDR_22108803_ChIP-Seq_LS180_Human1.72696680
39IGF1R_20145208_ChIP-Seq_DFB_Human1.71602697
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66847784
41AR_21572438_ChIP-Seq_LNCaP_Human1.63492858
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62854345
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56242264
44RNF2_27304074_Chip-Seq_NSC_Mouse1.53102156
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.52692299
46CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.51554283
47* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.51054315
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50309290
49ZNF274_21170338_ChIP-Seq_K562_Hela1.46213179
50POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45622280
51CTCF_27219007_Chip-Seq_Bcells_Human1.44809097
52WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43403282
53AR_25329375_ChIP-Seq_VCAP_Human1.43304649
54SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41297996
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40183807
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40119270
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.39993762
58ZFP281_27345836_Chip-Seq_ESCs_Mouse1.34905030
59ERG_21242973_ChIP-ChIP_JURKAT_Human1.34339323
60OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29935641
61ER_23166858_ChIP-Seq_MCF-7_Human1.29203854
62MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.29092279
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.29040254
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.28341896
65RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27865310
66FUS_26573619_Chip-Seq_HEK293_Human1.27434196
67TET1_21490601_ChIP-Seq_MESCs_Mouse1.27200307
68ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.23963072
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23259691
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21526982
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21445666
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20879888
73SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.20383710
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20188245
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.19913754
76* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.19708835
77LXR_22292898_ChIP-Seq_THP-1_Human1.18157830
78NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17457239
79MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13012570
80SMAD_19615063_ChIP-ChIP_OVARY_Human1.12967515
81GATA1_26923725_Chip-Seq_HPCs_Mouse1.11755258
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.09089800
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07523668
84STAT3_23295773_ChIP-Seq_U87_Human1.07410115
85AR_19668381_ChIP-Seq_PC3_Human1.07381813
86RUNX2_22187159_ChIP-Seq_PCA_Human1.06559019
87TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05399746
88* JUN_21703547_ChIP-Seq_K562_Human1.04132667
89TCF4_23295773_ChIP-Seq_U87_Human1.02636667
90BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02398187
91DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02203073
92MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00506749
93CDX2_19796622_ChIP-Seq_MESCs_Mouse1.00023089
94P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99665639
95OCT4_19829295_ChIP-Seq_ESCs_Human0.99100394
96PRDM14_20953172_ChIP-Seq_ESCs_Human0.98934608
97EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.97577716
98SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96180806
99SMC4_20622854_ChIP-Seq_HELA_Human0.94565194
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94260636
101FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94068440
102NANOG_18555785_Chip-Seq_ESCs_Mouse0.93957957
103TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93232187
104CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93154115
105TP53_20018659_ChIP-ChIP_R1E_Mouse0.92408017
106SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.92344735
107ARNT_22903824_ChIP-Seq_MCF-7_Human0.92305800
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91900272
109AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91548419
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91408322
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89827853
112RING1B_27294783_Chip-Seq_NPCs_Mouse0.89383443
113TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89196362
114KDM2B_26808549_Chip-Seq_REH_Human0.88955335
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88886556
116NR3C1_21868756_ChIP-Seq_MCF10A_Human0.88792757
117CBP_20019798_ChIP-Seq_JUKART_Human0.87088532
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87088532
119* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.87035600
120CREB1_26743006_Chip-Seq_LNCaP_Human0.86760638
121DPY_21335234_ChIP-Seq_ESCs_Mouse0.86019392
122EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.85984361
123KLF4_19829295_ChIP-Seq_ESCs_Human0.85138694
124TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84788536
125KDM2B_26808549_Chip-Seq_SUP-B15_Human0.84364292
126FLI1_21867929_ChIP-Seq_TH2_Mouse0.83920688
127SMAD3_21741376_ChIP-Seq_ESCs_Human0.83592894
128TP53_18474530_ChIP-ChIP_U2OS_Human0.83409311
129SRY_22984422_ChIP-ChIP_TESTIS_Rat0.83034600
130ESR2_21235772_ChIP-Seq_MCF-7_Human0.82807429
131TAL1_26923725_Chip-Seq_HPCs_Mouse0.81339092
132WT1_25993318_ChIP-Seq_PODOCYTE_Human0.81307534
133RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.80506415
134DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.79858560
135SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.79571069
136RUNX1_26923725_Chip-Seq_HPCs_Mouse0.78394912
137* P68_20966046_ChIP-Seq_HELA_Human0.78063158
138UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.74083909
139ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.73011970
140GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.72984133
141NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.72591025
142EGR1_19032775_ChIP-ChIP_M12_Human0.72309240
143SMAD4_21741376_ChIP-Seq_ESCs_Human0.71624582
144TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.71189567
145POU5F1_16518401_ChIP-PET_MESCs_Mouse0.70410207
146TRIM28_21343339_ChIP-Seq_HEK293_Human0.69008859

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.71829208
2MP0004859_abnormal_synaptic_plasticity4.69907881
3MP0003635_abnormal_synaptic_transmissio3.71839015
4MP0009745_abnormal_behavioral_response3.26144447
5MP0001968_abnormal_touch/_nociception3.18011454
6MP0002063_abnormal_learning/memory/cond3.15900941
7MP0002064_seizures3.06995134
8MP0009046_muscle_twitch3.03950679
9MP0002572_abnormal_emotion/affect_behav2.95228183
10MP0006276_abnormal_autonomic_nervous2.93674274
11MP0003122_maternal_imprinting2.70521551
12MP0000013_abnormal_adipose_tissue2.70373816
13MP0002736_abnormal_nociception_after2.70005330
14MP0004270_analgesia2.62572865
15MP0005423_abnormal_somatic_nervous2.59703929
16MP0002272_abnormal_nervous_system2.54176651
17MP0002822_catalepsy2.39710953
18MP0001440_abnormal_grooming_behavior2.38051409
19MP0001486_abnormal_startle_reflex2.36005137
20MP0002734_abnormal_mechanical_nocicepti2.33128326
21MP0001501_abnormal_sleep_pattern2.32642437
22MP0002735_abnormal_chemical_nociception2.28431630
23MP0001529_abnormal_vocalization2.23308259
24MP0002067_abnormal_sensory_capabilities2.13898135
25MP0005645_abnormal_hypothalamus_physiol2.13109611
26MP0005646_abnormal_pituitary_gland2.05345079
27MP0003283_abnormal_digestive_organ2.01425750
28MP0003787_abnormal_imprinting1.97754835
29MP0002733_abnormal_thermal_nociception1.88210631
30MP0004142_abnormal_muscle_tone1.86961553
31MP0001970_abnormal_pain_threshold1.84396310
32MP0004924_abnormal_behavior1.79903557
33MP0005386_behavior/neurological_phenoty1.79903557
34MP0002557_abnormal_social/conspecific_i1.76155442
35MP0002184_abnormal_innervation1.73783217
36MP0001984_abnormal_olfaction1.71921299
37MP0003879_abnormal_hair_cell1.69042351
38MP0000778_abnormal_nervous_system1.61378334
39MP0001905_abnormal_dopamine_level1.57542391
40MP0002102_abnormal_ear_morphology1.57050876
41MP0002837_dystrophic_cardiac_calcinosis1.56905274
42MP0001502_abnormal_circadian_rhythm1.49441005
43MP0003329_amyloid_beta_deposits1.45262577
44MP0000751_myopathy1.43888941
45MP0000920_abnormal_myelination1.37698932
46MP0003690_abnormal_glial_cell1.37009436
47MP0002876_abnormal_thyroid_physiology1.33541839
48MP0004811_abnormal_neuron_physiology1.33243547
49MP0005551_abnormal_eye_electrophysiolog1.32673007
50MP0002066_abnormal_motor_capabilities/c1.32227636
51MP0008569_lethality_at_weaning1.28203476
52MP0002882_abnormal_neuron_morphology1.27907954
53MP0000955_abnormal_spinal_cord1.27274585
54MP0009780_abnormal_chondrocyte_physiolo1.26107442
55MP0001188_hyperpigmentation1.22708597
56MP0004742_abnormal_vestibular_system1.18209191
57MP0003121_genomic_imprinting1.15814612
58MP0003632_abnormal_nervous_system1.13463204
59MP0002909_abnormal_adrenal_gland1.12700559
60MP0005167_abnormal_blood-brain_barrier1.08954306
61MP0004858_abnormal_nervous_system1.07026375
62MP0000566_synostosis1.06750474
63MP0010386_abnormal_urinary_bladder1.03732383
64MP0000631_abnormal_neuroendocrine_gland1.01407682
65MP0003123_paternal_imprinting0.98645866
66MP0002152_abnormal_brain_morphology0.98285041
67MP0002229_neurodegeneration0.96172222
68MP0003633_abnormal_nervous_system0.95477129
69MP0002938_white_spotting0.93414627
70MP0002638_abnormal_pupillary_reflex0.92266764
71MP0002069_abnormal_eating/drinking_beha0.90518499
72MP0001963_abnormal_hearing_physiology0.88979141
73MP0004145_abnormal_muscle_electrophysio0.87225377
74MP0006292_abnormal_olfactory_placode0.85549420
75MP0004147_increased_porphyrin_level0.85013382
76MP0003631_nervous_system_phenotype0.82023963
77MP0006072_abnormal_retinal_apoptosis0.80504071
78MP0005535_abnormal_body_temperature0.80416516
79MP0008872_abnormal_physiological_respon0.79889589
80MP0005377_hearing/vestibular/ear_phenot0.79061468
81MP0003878_abnormal_ear_physiology0.79061468
82MP0002752_abnormal_somatic_nervous0.79029973
83MP0000639_abnormal_adrenal_gland0.78100709
84MP0001664_abnormal_digestion0.77641008
85MP0002089_abnormal_postnatal_growth/wei0.76645565
86MP0004885_abnormal_endolymph0.75579764
87MP0004085_abnormal_heartbeat0.75310905
88MP0004215_abnormal_myocardial_fiber0.74864868
89MP0003938_abnormal_ear_development0.73161922
90MP0005394_taste/olfaction_phenotype0.72393077
91MP0005499_abnormal_olfactory_system0.72393077
92MP0001485_abnormal_pinna_reflex0.72059935
93MP0003861_abnormal_nervous_system0.71355328
94MP0001346_abnormal_lacrimal_gland0.71117276
95MP0008877_abnormal_DNA_methylation0.64882851
96MP0000003_abnormal_adipose_tissue0.64416907
97MP0005379_endocrine/exocrine_gland_phen0.63544296
98MP0005253_abnormal_eye_physiology0.63123200
99MP0003646_muscle_fatigue0.62741560
100MP0008874_decreased_physiological_sensi0.62741473
101MP0006035_abnormal_mitochondrial_morpho0.61906601
102MP0004133_heterotaxia0.61737536
103MP0002249_abnormal_larynx_morphology0.61044157
104MP0001943_abnormal_respiration0.60711168
105MP0010769_abnormal_survival0.60577712
106MP0000026_abnormal_inner_ear0.57699847
107MP0002090_abnormal_vision0.57660464
108MP0003634_abnormal_glial_cell0.57553684
109MP0002751_abnormal_autonomic_nervous0.56994670
110MP0010768_mortality/aging0.56472991
111MP0002332_abnormal_exercise_endurance0.55470477
112MP0003137_abnormal_impulse_conducting0.54153482
113MP0004130_abnormal_muscle_cell0.53797592
114MP0001177_atelectasis0.53753893
115MP0000604_amyloidosis0.53712888
116MP0003075_altered_response_to0.53712599
117MP0010770_preweaning_lethality0.53025032
118MP0002082_postnatal_lethality0.53025032
119MP0002653_abnormal_ependyma_morphology0.51124439
120MP0001299_abnormal_eye_distance/0.50260643
121MP0003956_abnormal_body_size0.48924000
122MP0005409_darkened_coat_color0.48652681

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.15267928
2Myokymia (HP:0002411)5.01793721
3Focal seizures (HP:0007359)4.87372084
4Febrile seizures (HP:0002373)4.82746863
5Atonic seizures (HP:0010819)4.81518229
6Visual hallucinations (HP:0002367)4.71637572
7Epileptic encephalopathy (HP:0200134)4.66899172
8Absence seizures (HP:0002121)4.07760550
9Hyperventilation (HP:0002883)3.96236997
10Polyphagia (HP:0002591)3.87499511
11Failure to thrive in infancy (HP:0001531)3.74522761
12Progressive cerebellar ataxia (HP:0002073)3.74449146
13Dialeptic seizures (HP:0011146)3.68124638
14Neurofibrillary tangles (HP:0002185)3.64641525
15Broad-based gait (HP:0002136)3.51415056
16Generalized tonic-clonic seizures (HP:0002069)3.42398062
17Spastic gait (HP:0002064)3.42300630
18Abnormal hair whorl (HP:0010721)3.40212479
19Poor eye contact (HP:0000817)3.31909195
20Abnormal eating behavior (HP:0100738)3.26749605
21Papilledema (HP:0001085)3.07734438
22Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.07288306
23Pheochromocytoma (HP:0002666)3.03436641
24Progressive inability to walk (HP:0002505)3.02082750
25Impaired social interactions (HP:0000735)3.02054692
26Abnormal social behavior (HP:0012433)3.02054692
27Progressive macrocephaly (HP:0004481)2.97726600
28Limb dystonia (HP:0002451)2.97675081
29Status epilepticus (HP:0002133)2.93085540
30Anxiety (HP:0000739)2.91493086
31Acute necrotizing encephalopathy (HP:0006965)2.86528402
32Delusions (HP:0000746)2.85696577
33Gait imbalance (HP:0002141)2.85162119
34Poor suck (HP:0002033)2.83580940
35Urinary urgency (HP:0000012)2.77637903
36Abnormal mitochondria in muscle tissue (HP:0008316)2.77126921
37Neuroendocrine neoplasm (HP:0100634)2.75290801
38Annular pancreas (HP:0001734)2.75126106
39Cerebral hypomyelination (HP:0006808)2.74248511
40Epileptiform EEG discharges (HP:0011182)2.71108469
41Craniofacial dystonia (HP:0012179)2.60128783
42EEG with generalized epileptiform discharges (HP:0011198)2.59392120
43Hemiplegia (HP:0002301)2.57936696
44Inability to walk (HP:0002540)2.57925589
45Intention tremor (HP:0002080)2.57048262
46Peripheral hypomyelination (HP:0007182)2.53878933
47Excessive salivation (HP:0003781)2.52189081
48Drooling (HP:0002307)2.52189081
49Akinesia (HP:0002304)2.50447927
50Gaze-evoked nystagmus (HP:0000640)2.49717760
51Oligomenorrhea (HP:0000876)2.49096243
52Congenital primary aphakia (HP:0007707)2.48544420
53Truncal ataxia (HP:0002078)2.48517827
54Esotropia (HP:0000565)2.48346238
55Neuronal loss in central nervous system (HP:0002529)2.48213778
56Hypsarrhythmia (HP:0002521)2.48153465
57Fetal akinesia sequence (HP:0001989)2.48049891
58Impaired vibration sensation in the lower limbs (HP:0002166)2.47900416
59Insomnia (HP:0100785)2.45944796
60Mitochondrial inheritance (HP:0001427)2.45219112
61Narrow nasal bridge (HP:0000446)2.44552077
62Dysdiadochokinesis (HP:0002075)2.43224106
63Medial flaring of the eyebrow (HP:0010747)2.43045739
64Obstructive sleep apnea (HP:0002870)2.42771154
65Amblyopia (HP:0000646)2.42671348
66Lower limb muscle weakness (HP:0007340)2.39382756
67Depression (HP:0000716)2.39270215
68Split foot (HP:0001839)2.39106956
69Abnormality of the corticospinal tract (HP:0002492)2.35467533
70Tetraplegia (HP:0002445)2.35222757
71Clonus (HP:0002169)2.34085871
72Nephrogenic diabetes insipidus (HP:0009806)2.33778004
73Aplasia involving bones of the upper limbs (HP:0009823)2.32405741
74Aplasia of the phalanges of the hand (HP:0009802)2.32405741
75Aplasia involving bones of the extremities (HP:0009825)2.32405741
76Supranuclear gaze palsy (HP:0000605)2.29725668
77Mutism (HP:0002300)2.24164311
78Dysmetria (HP:0001310)2.21889578
79Abnormality of the lower motor neuron (HP:0002366)2.20369170
80Hyperthyroidism (HP:0000836)2.18405279
81Ankle clonus (HP:0011448)2.18139991
82Renal Fanconi syndrome (HP:0001994)2.16574596
83Ventricular fibrillation (HP:0001663)2.16383471
84Specific learning disability (HP:0001328)2.14389518
85Protruding tongue (HP:0010808)2.12924349
86Fragile nails (HP:0001808)2.11042027
87Broad palm (HP:0001169)2.10807630
88Abnormality of the labia minora (HP:0012880)2.08067089
89Agitation (HP:0000713)2.07454886
90Hypoventilation (HP:0002791)2.07141872
91Abnormality of binocular vision (HP:0011514)2.05145632
92Diplopia (HP:0000651)2.05145632
93Bronchomalacia (HP:0002780)2.05054584
94Apathy (HP:0000741)2.04576164
95Entropion (HP:0000621)2.03155005
96Acute encephalopathy (HP:0006846)2.02695662
97Incomplete penetrance (HP:0003829)2.01744814
98Dynein arm defect of respiratory motile cilia (HP:0012255)2.01127810
99Absent/shortened dynein arms (HP:0200106)2.01127810
100Bradykinesia (HP:0002067)2.00651992
101Psychosis (HP:0000709)2.00328514
102Increased CSF lactate (HP:0002490)2.00278930
103Poikiloderma (HP:0001029)2.00006504
104Vaginal atresia (HP:0000148)1.97600395
105Scanning speech (HP:0002168)1.96656821
106Genital tract atresia (HP:0001827)1.95653004
107Stereotypic behavior (HP:0000733)1.93964217
108Megalencephaly (HP:0001355)1.93565406
109Impaired vibratory sensation (HP:0002495)1.93286305
110Relative macrocephaly (HP:0004482)1.91963033
111Action tremor (HP:0002345)1.91958814
112Hemiparesis (HP:0001269)1.91162011
113Morphological abnormality of the pyramidal tract (HP:0002062)1.91050277
114Postural instability (HP:0002172)1.90811221
115Blue irides (HP:0000635)1.89979508
116Spastic tetraparesis (HP:0001285)1.89678319
117Pointed chin (HP:0000307)1.89275568
118Abnormal ciliary motility (HP:0012262)1.88892997
119Hepatocellular necrosis (HP:0001404)1.87022374
120Brittle hair (HP:0002299)1.86409352
121Rigidity (HP:0002063)1.86115220
122Absent speech (HP:0001344)1.85516617
123Spinal canal stenosis (HP:0003416)1.85282744
124Optic disc pallor (HP:0000543)1.84370963
125CNS hypomyelination (HP:0003429)1.84174935
126Urinary bladder sphincter dysfunction (HP:0002839)1.82452629
127Torticollis (HP:0000473)1.82440156
128Generalized hypotonia (HP:0001290)1.81162590
129Fair hair (HP:0002286)1.80905456
130Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80334524
131Degeneration of the lateral corticospinal tracts (HP:0002314)1.80334524
132Thickened helices (HP:0000391)1.80108188
133Diminished motivation (HP:0000745)1.78750308
134Generalized myoclonic seizures (HP:0002123)1.78598148
135Impaired smooth pursuit (HP:0007772)1.77182994
136Poor coordination (HP:0002370)1.76279741
137Decreased subcutaneous fat (HP:0001002)1.76005535
138Scrotal hypoplasia (HP:0000046)1.75614506
139Exotropia (HP:0000577)1.75099619
140Focal dystonia (HP:0004373)1.74961289
141Thyroid-stimulating hormone excess (HP:0002925)1.72651259
142Sleep apnea (HP:0010535)1.72642465
143Cerebral inclusion bodies (HP:0100314)1.72371356
144Choreoathetosis (HP:0001266)1.71318151
145Hypoplasia of the corpus callosum (HP:0002079)1.70791155
146Hand muscle atrophy (HP:0009130)1.65468986
147Abnormality of ocular smooth pursuit (HP:0000617)1.61792328
148Prolonged QT interval (HP:0001657)1.60424678
149Lower limb asymmetry (HP:0100559)1.60073407
150Spastic tetraplegia (HP:0002510)1.58181824
151Alacrima (HP:0000522)1.57693780
152Hammertoe (HP:0001765)1.56356187

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.49359926
2CASK4.35922810
3MAP3K123.82099926
4MAP3K43.14945893
5EPHA43.13142997
6MAP3K93.07824845
7MAP2K73.00498126
8MARK12.94511371
9MINK12.42650228
10NTRK22.07496651
11MAP2K42.06336446
12TNIK1.87406088
13ARAF1.82651579
14CDK191.76656871
15PLK21.70895604
16DAPK21.68599077
17BRAF1.68332838
18MAPK131.64929758
19PNCK1.61871182
20GRK51.59353869
21PINK11.55492692
22DAPK11.54746166
23FES1.44404149
24PRPF4B1.43777842
25RIPK11.37512484
26NME11.36085457
27CDK51.32813863
28PRKCG1.28586421
29TNK21.27628567
30KSR11.26933109
31IRAK21.26456749
32SIK31.22623406
33GRK71.20905905
34CAMK2A1.17308087
35MARK21.12216536
36OXSR11.12120517
37RIPK41.11643367
38UHMK11.10507911
39PAK61.08771999
40TSSK61.05581568
41AKT31.03710187
42CAMK2B1.03488485
43ADRBK20.98214016
44SIK20.96857659
45PHKG20.92750970
46PHKG10.92750970
47KSR20.92044904
48SGK2230.89787762
49SGK4940.89787762
50ALK0.85361039
51MYLK0.84110253
52SGK20.83978744
53MAP3K130.83368415
54MAPK120.83214450
55PRKCE0.81793338
56FGFR20.79807012
57PKN10.78321614
58NEK60.77904934
59CAMK40.77482568
60CDK180.76704477
61CDK140.76702294
62DYRK1A0.76011604
63ICK0.75307502
64NTRK10.75238258
65CAMK2D0.73365129
66TAOK10.73100212
67BCR0.71410803
68CAMKK10.71108775
69CDK150.69566595
70CAMKK20.69420269
71CAMK10.69110770
72PTK2B0.66360387
73CAMK2G0.66169273
74MAPK100.66017891
75PDK10.63354845
76WNK30.62653838
77DMPK0.62096724
78FER0.61910762
79CSNK1G20.61652361
80CCNB10.60895626
81BMPR20.60429945
82WNK40.60216274
83PAK30.59557335
84ADRBK10.59061182
85PDPK10.58880709
86CDK11A0.57573713
87MUSK0.57146290
88BRSK10.56896409
89RAF10.56510541
90ERBB20.56381657
91SGK10.56246853
92EEF2K0.54846795
93PRKCH0.54774675
94STK110.54724706
95FGR0.53736821
96RET0.53712301
97TYRO30.52812377
98STK160.52173090
99STK380.49336371
100MAP3K60.47135329
101RPS6KA20.47071326
102ROCK20.44804452
103BMPR1B0.44409171
104MAP3K20.42525354
105CSNK1G30.42333646
106PRKACA0.42060621
107SGK30.39914447
108PDK30.39763080
109PDK40.39763080
110MAP3K110.39627959
111INSRR0.39477455
112FGFR40.39016611
113MAP2K60.38850667
114PRKD30.38743375
115PRKG10.38347236
116DYRK20.38175919
117PRKCZ0.37147564
118PRKG20.36195481
119DAPK30.35395435
120FYN0.34923466
121RPS6KA30.34907969
122MAPK80.34516891
123LATS20.33824029
124FGFR30.32800965
125CSNK1E0.32303198
126PRKCA0.31780323
127MAPKAPK50.31733177
128LIMK10.30613495
129GSK3B0.30424830
130WNK10.30415625
131ROCK10.29871429
132CAMK1D0.29707022

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.63693221
2Synaptic vesicle cycle_Homo sapiens_hsa047213.80823042
3Collecting duct acid secretion_Homo sapiens_hsa049663.07152774
4GABAergic synapse_Homo sapiens_hsa047272.93244634
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.86735573
6Oxidative phosphorylation_Homo sapiens_hsa001902.59703794
7Morphine addiction_Homo sapiens_hsa050322.59403311
8Olfactory transduction_Homo sapiens_hsa047402.51032179
9Circadian entrainment_Homo sapiens_hsa047132.40330442
10Long-term potentiation_Homo sapiens_hsa047202.33307100
11Amphetamine addiction_Homo sapiens_hsa050312.30207393
12Glutamatergic synapse_Homo sapiens_hsa047242.27375447
13Taste transduction_Homo sapiens_hsa047422.05860733
14Dopaminergic synapse_Homo sapiens_hsa047282.04965270
15Vibrio cholerae infection_Homo sapiens_hsa051101.92026724
16Parkinsons disease_Homo sapiens_hsa050121.91532628
17Serotonergic synapse_Homo sapiens_hsa047261.86250383
18Long-term depression_Homo sapiens_hsa047301.76132317
19Salivary secretion_Homo sapiens_hsa049701.73243925
20Insulin secretion_Homo sapiens_hsa049111.72182636
21Cocaine addiction_Homo sapiens_hsa050301.71580694
22Alzheimers disease_Homo sapiens_hsa050101.69283736
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.66972841
24Vitamin B6 metabolism_Homo sapiens_hsa007501.64960146
25Cholinergic synapse_Homo sapiens_hsa047251.62789661
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62066648
27Renin secretion_Homo sapiens_hsa049241.59449481
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.59037285
29Cardiac muscle contraction_Homo sapiens_hsa042601.56710031
30Calcium signaling pathway_Homo sapiens_hsa040201.49305162
31Oxytocin signaling pathway_Homo sapiens_hsa049211.48814043
32Gastric acid secretion_Homo sapiens_hsa049711.44050274
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.41704968
34Huntingtons disease_Homo sapiens_hsa050161.37555964
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.35412221
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34724282
37Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.29624473
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21213338
39Gap junction_Homo sapiens_hsa045401.18780230
40GnRH signaling pathway_Homo sapiens_hsa049121.16483953
41cAMP signaling pathway_Homo sapiens_hsa040241.03011022
42Axon guidance_Homo sapiens_hsa043601.00738746
43Phototransduction_Homo sapiens_hsa047441.00275178
44Bile secretion_Homo sapiens_hsa049760.98209927
45SNARE interactions in vesicular transport_Homo sapiens_hsa041300.93984238
46Estrogen signaling pathway_Homo sapiens_hsa049150.91464010
47Rheumatoid arthritis_Homo sapiens_hsa053230.89699328
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.89346418
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.86185354
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83101990
51Melanogenesis_Homo sapiens_hsa049160.80455034
52ErbB signaling pathway_Homo sapiens_hsa040120.79850088
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.78500179
54cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77915189
55Arginine biosynthesis_Homo sapiens_hsa002200.77887265
56Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.77702631
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.77380706
58Type II diabetes mellitus_Homo sapiens_hsa049300.76994505
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76777845
60Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.75714349
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74977863
62Arginine and proline metabolism_Homo sapiens_hsa003300.72718377
63Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69609139
64Glioma_Homo sapiens_hsa052140.67327328
65Type I diabetes mellitus_Homo sapiens_hsa049400.64176147
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63466001
67Dilated cardiomyopathy_Homo sapiens_hsa054140.60921799
68Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60222827
69Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59232999
70Oocyte meiosis_Homo sapiens_hsa041140.58978093
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56853635
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.56527457
73Prion diseases_Homo sapiens_hsa050200.53737708
74Fatty acid biosynthesis_Homo sapiens_hsa000610.53503564
75Phagosome_Homo sapiens_hsa041450.52541197
76MAPK signaling pathway_Homo sapiens_hsa040100.49375476
77Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48952059
78Thyroid hormone synthesis_Homo sapiens_hsa049180.48530963
79Pancreatic secretion_Homo sapiens_hsa049720.45794848
80Alcoholism_Homo sapiens_hsa050340.45103886
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44856605
82Choline metabolism in cancer_Homo sapiens_hsa052310.43523866
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.43495258
84Histidine metabolism_Homo sapiens_hsa003400.42827705
85Glucagon signaling pathway_Homo sapiens_hsa049220.42706796
86Inositol phosphate metabolism_Homo sapiens_hsa005620.42548163
87Ras signaling pathway_Homo sapiens_hsa040140.39635350
88AMPK signaling pathway_Homo sapiens_hsa041520.39493198
89Mineral absorption_Homo sapiens_hsa049780.39059625
90Circadian rhythm_Homo sapiens_hsa047100.38140400
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37900735
92Endocytosis_Homo sapiens_hsa041440.37717982
93mTOR signaling pathway_Homo sapiens_hsa041500.37608816
94Butanoate metabolism_Homo sapiens_hsa006500.36592414
95HIF-1 signaling pathway_Homo sapiens_hsa040660.35930761
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35433508
97Hippo signaling pathway_Homo sapiens_hsa043900.34440169
98Renal cell carcinoma_Homo sapiens_hsa052110.33861260
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33528743
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33313276
101Hedgehog signaling pathway_Homo sapiens_hsa043400.32896968
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32822885
103Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29458669
104Ovarian steroidogenesis_Homo sapiens_hsa049130.28738395
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.27645132
106Tight junction_Homo sapiens_hsa045300.25590153
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.25348485
108VEGF signaling pathway_Homo sapiens_hsa043700.24972021
109Rap1 signaling pathway_Homo sapiens_hsa040150.24465779
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.23105510
111Cyanoamino acid metabolism_Homo sapiens_hsa004600.22865394
112Insulin signaling pathway_Homo sapiens_hsa049100.22555813
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.21560396
114Steroid biosynthesis_Homo sapiens_hsa001000.21335670
115Melanoma_Homo sapiens_hsa052180.20903989
116Pyruvate metabolism_Homo sapiens_hsa006200.20479082
117Wnt signaling pathway_Homo sapiens_hsa043100.19608644
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.16141154
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.15763200
120Fructose and mannose metabolism_Homo sapiens_hsa000510.15684690

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