PNLIPRP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)8.99034313
2transcytosis (GO:0045056)8.61862251
3cobalamin metabolic process (GO:0009235)8.06213332
4daunorubicin metabolic process (GO:0044597)7.49190881
5polyketide metabolic process (GO:0030638)7.49190881
6doxorubicin metabolic process (GO:0044598)7.49190881
7peptidyl-proline hydroxylation (GO:0019511)7.46011260
8cholesterol catabolic process (GO:0006707)7.41665590
9sterol catabolic process (GO:0016127)7.41665590
10regulation of phospholipase A2 activity (GO:0032429)7.11674683
11negative regulation of digestive system process (GO:0060457)6.91079893
12aminoglycoside antibiotic metabolic process (GO:0030647)6.74254921
13negative regulation of epidermis development (GO:0045683)6.40028275
14cysteine metabolic process (GO:0006534)6.16436360
15Golgi transport vesicle coating (GO:0048200)5.79000021
16COPI coating of Golgi vesicle (GO:0048205)5.79000021
17protein hydroxylation (GO:0018126)5.75076944
18proline biosynthetic process (GO:0006561)5.59479036
19branched-chain amino acid catabolic process (GO:0009083)5.46040486
20ceramide catabolic process (GO:0046514)5.43394359
21regulation of triglyceride catabolic process (GO:0010896)5.33934555
22valine metabolic process (GO:0006573)5.23112183
23tetrapyrrole metabolic process (GO:0033013)5.14723273
24intestinal epithelial cell development (GO:0060576)4.87324926
25regulation of keratinocyte differentiation (GO:0045616)4.86351585
26activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.83321703
27branched-chain amino acid metabolic process (GO:0009081)4.78250814
28cellular modified amino acid catabolic process (GO:0042219)4.74062851
29leukotriene biosynthetic process (GO:0019370)4.68759457
30zinc ion transport (GO:0006829)4.67333462
31glycoside metabolic process (GO:0016137)4.62024440
32positive regulation of nuclease activity (GO:0032075)4.61729406
33regulation of keratinocyte proliferation (GO:0010837)4.60587377
34protein maturation by protein folding (GO:0022417)4.51691205
35mitochondrial calcium ion transport (GO:0006851)4.51668396
36response to endoplasmic reticulum stress (GO:0034976)4.46132185
37angiotensin maturation (GO:0002003)4.45924305
38homocysteine metabolic process (GO:0050667)4.37250334
39endoplasmic reticulum unfolded protein response (GO:0030968)4.34413378
40serine family amino acid biosynthetic process (GO:0009070)4.32875825
41antibacterial humoral response (GO:0019731)4.30721812
42cellular response to unfolded protein (GO:0034620)4.22416256
43regulation of nuclease activity (GO:0032069)4.20138243
44maintenance of protein localization in organelle (GO:0072595)4.19631437
45signal peptide processing (GO:0006465)4.15295417
464-hydroxyproline metabolic process (GO:0019471)4.09742715
47neutrophil mediated immunity (GO:0002446)4.09459726
48GDP-mannose metabolic process (GO:0019673)4.05076787
49regulation of guanylate cyclase activity (GO:0031282)4.04074621
50antimicrobial humoral response (GO:0019730)4.03441422
51primary alcohol catabolic process (GO:0034310)4.01683592
52cellular response to topologically incorrect protein (GO:0035967)4.01330382
53positive regulation of heat generation (GO:0031652)4.00612269
54ER-nucleus signaling pathway (GO:0006984)4.00327733
55aspartate family amino acid catabolic process (GO:0009068)3.94832442
56COPII vesicle coating (GO:0048208)3.94349622
57water-soluble vitamin metabolic process (GO:0006767)3.91727245
58phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.84062391
59glutamine metabolic process (GO:0006541)3.81838792
60regulation of bile acid biosynthetic process (GO:0070857)3.80514774
61regulation of fever generation (GO:0031620)3.79561317
62steroid catabolic process (GO:0006706)3.76754544
63progesterone metabolic process (GO:0042448)3.74698914
64proline metabolic process (GO:0006560)3.73352648
65mucosal immune response (GO:0002385)3.72381691
66endocrine pancreas development (GO:0031018)3.71658149
67cellular glucuronidation (GO:0052695)3.70136098
68phosphatidylserine metabolic process (GO:0006658)3.66351764
69glucuronate metabolic process (GO:0019585)3.64520407
70uronic acid metabolic process (GO:0006063)3.64520407
71digestive system process (GO:0022600)3.63204110
72icosanoid secretion (GO:0032309)3.61096826
73arachidonic acid secretion (GO:0050482)3.61096826
74ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.60144227
75phosphatidylcholine acyl-chain remodeling (GO:0036151)3.59686378
76cellular protein catabolic process (GO:0044257)3.55901003
77sphingolipid catabolic process (GO:0030149)3.55276495
78negative regulation of epidermal cell differentiation (GO:0045605)3.54362653
79creatine metabolic process (GO:0006600)3.54055014
80ER overload response (GO:0006983)3.53813080
81positive regulation of guanylate cyclase activity (GO:0031284)3.51001359
82coenzyme catabolic process (GO:0009109)3.50529058
83regulation of cholesterol homeostasis (GO:2000188)3.49958831
84response to unfolded protein (GO:0006986)3.47894416
85cyclooxygenase pathway (GO:0019371)3.47521345
86retinoid metabolic process (GO:0001523)3.46144632
87retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.42257937
88regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.41381042
89L-serine metabolic process (GO:0006563)3.39385072
90phosphatidic acid biosynthetic process (GO:0006654)3.38549175
91phosphatidic acid metabolic process (GO:0046473)3.38549175
92organ or tissue specific immune response (GO:0002251)3.37922101
93cholesterol transport (GO:0030301)3.36494403
94sterol transport (GO:0015918)3.36494403
95* membrane lipid catabolic process (GO:0046466)3.35855365
96response to topologically incorrect protein (GO:0035966)3.34901583
97protein N-linked glycosylation via asparagine (GO:0018279)3.34790911
98peptidyl-asparagine modification (GO:0018196)3.32660050
99serine family amino acid metabolic process (GO:0009069)3.31371349
100regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.31368631
101vitamin metabolic process (GO:0006766)3.31323372
102diterpenoid metabolic process (GO:0016101)3.28075872
103alditol phosphate metabolic process (GO:0052646)3.23695311
104erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.22502257
105L-phenylalanine catabolic process (GO:0006559)3.22502257
106innate immune response in mucosa (GO:0002227)3.20804053
107macroautophagy (GO:0016236)3.18613225
108mitochondrion distribution (GO:0048311)3.17864904
109phosphatidylinositol acyl-chain remodeling (GO:0036149)3.17252672
110negative regulation of hormone metabolic process (GO:0032351)3.12123193
111cell redox homeostasis (GO:0045454)3.10277173
112myeloid leukocyte mediated immunity (GO:0002444)3.08409821
113L-alpha-amino acid transmembrane transport (GO:1902475)3.07646880
114erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.07565475
115L-phenylalanine metabolic process (GO:0006558)3.07565475
116regulation of digestive system process (GO:0044058)3.07016254
117regulation of vitamin metabolic process (GO:0030656)3.06828048
118regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902175)3.06439482
119calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.05648447
120acute-phase response (GO:0006953)3.05511979
121protein N-linked glycosylation (GO:0006487)3.05184402
122positive regulation of triglyceride metabolic process (GO:0090208)3.05069850
123quinone metabolic process (GO:1901661)3.02736765
124positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.01506569
125regulation of epidermal cell differentiation (GO:0045604)3.00876362
126biotin metabolic process (GO:0006768)3.00828339
127sulfur amino acid biosynthetic process (GO:0000097)3.00739814
128phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.99185434
129regulation of heat generation (GO:0031650)2.98173477
130fatty acid derivative transport (GO:1901571)2.97045502
131icosanoid transport (GO:0071715)2.97045502
132peptide catabolic process (GO:0043171)2.96416948
133terpenoid metabolic process (GO:0006721)2.93443341
134multicellular organismal catabolic process (GO:0044243)2.93343161
135glycine transport (GO:0015816)2.92355967
136phosphatidylserine acyl-chain remodeling (GO:0036150)2.90496727
137defense response to Gram-positive bacterium (GO:0050830)2.89126665
138leukotriene metabolic process (GO:0006691)2.87785589
139renal absorption (GO:0070293)2.87534291
140endothelial cell migration (GO:0043542)2.84130469
141regulation of oxidative stress-induced cell death (GO:1903201)2.83009318
142nucleotide-sugar biosynthetic process (GO:0009226)2.81974876
143NADH metabolic process (GO:0006734)2.81947755
144multicellular organismal metabolic process (GO:0044236)2.81451013
145UDP-N-acetylglucosamine metabolic process (GO:0006047)2.79825660
146negative regulation of cell fate commitment (GO:0010454)2.78076117
147positive regulation of lipid catabolic process (GO:0050996)2.75103585
148phototransduction, visible light (GO:0007603)2.71411592
149epoxygenase P450 pathway (GO:0019373)2.70543830
150L-ascorbic acid metabolic process (GO:0019852)2.70163739
151negative regulation of epithelial cell differentiation (GO:0030857)2.67367342
152retinal metabolic process (GO:0042574)2.62862098
153regulation of systemic arterial blood pressure by hormone (GO:0001990)2.61720305
154regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.61720305
155endocrine process (GO:0050886)2.61720305
156phosphatidylglycerol metabolic process (GO:0046471)2.60505752
157fat-soluble vitamin biosynthetic process (GO:0042362)2.58999934
158intestinal cholesterol absorption (GO:0030299)18.9064831
159exocrine pancreas development (GO:0031017)15.7186113
160* digestion (GO:0007586)13.4351324
161protein retention in ER lumen (GO:0006621)12.3379279
162maintenance of protein localization in endoplasmic reticulum (GO:0035437)11.5239104

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.96455102
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.08073483
3STAT6_21828071_ChIP-Seq_BEAS2B_Human3.95810114
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.57765595
5SOX2_27498859_Chip-Seq_STOMACH_Mouse3.05480287
6GATA4_25053715_ChIP-Seq_YYC3_Human2.94787860
7ERG_21242973_ChIP-ChIP_JURKAT_Human2.86736628
8FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.83288521
9PPARA_22158963_ChIP-Seq_LIVER_Mouse2.81043167
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.75438304
11RXR_22158963_ChIP-Seq_LIVER_Mouse2.69271578
12GATA6_25053715_ChIP-Seq_YYC3_Human2.44966067
13CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.38000533
14LXR_22158963_ChIP-Seq_LIVER_Mouse2.36018033
15ESR1_21235772_ChIP-Seq_MCF-7_Human2.25090425
16ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.24286918
17STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.20742305
18GATA1_22025678_ChIP-Seq_K562_Human2.16421954
19ESR2_21235772_ChIP-Seq_MCF-7_Human2.15980475
20KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.12535273
21KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.12535273
22KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.12535273
23HTT_18923047_ChIP-ChIP_STHdh_Human2.00944620
24PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.85663452
25TCF4_18268006_ChIP-ChIP_LS174T_Human1.82572934
26TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71273447
27CDX2_20551321_ChIP-Seq_CACO-2_Human1.68662639
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.67313409
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.64840850
30PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.64143080
31EGR1_23403033_ChIP-Seq_LIVER_Mouse1.61279842
32CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.60461569
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.60296564
34HNFA_21074721_ChIP-Seq_CACO-2_Human1.58071984
35FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.55068297
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.53989798
37NFYA_21822215_ChIP-Seq_K562_Human1.53094073
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.52410201
39EGR1_19032775_ChIP-ChIP_M12_Human1.50332255
40ETV1_20927104_ChIP-Seq_GIST48_Human1.49460865
41RARG_19884340_ChIP-ChIP_MEFs_Mouse1.48954876
42CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.44731166
43GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.44728816
44CREB1_26743006_Chip-Seq_LNCaP_Human1.44212277
45SOX2_20726797_ChIP-Seq_SW620_Human1.43907064
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.43738065
47FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.42593704
48PHF8_20622853_ChIP-Seq_HELA_Human1.42215928
49TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.42209114
50PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.41914343
51GATA6_21074721_ChIP-Seq_CACO-2_Human1.40069866
52* HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.39994133
53TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39303806
54CHD1_26751641_Chip-Seq_LNCaP_Human1.37411423
55RBPJ_21746931_ChIP-Seq_IB4_Human1.35711569
56TRIM28_21343339_ChIP-Seq_HEK293_Human1.34577359
57P63_26484246_Chip-Seq_KERATINOCYTES_Human1.33147058
58LXR_22292898_ChIP-Seq_THP-1_Human1.30799270
59P68_20966046_ChIP-Seq_HELA_Human1.29753675
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28145946
61CBX2_22325352_ChIP-Seq_293T-Rex_Human1.28127312
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.26391638
63FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.25583128
64RUNX1_27514584_Chip-Seq_MCF-7_Human1.24354785
65CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22482105
66SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.21687035
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.21467285
68FOXO3_23340844_ChIP-Seq_DLD1_Human1.20960879
69SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.20468590
70* ATF3_27146783_Chip-Seq_COLON_Human1.19072029
71NFYB_21822215_ChIP-Seq_K562_Human1.18235883
72FOXA2_19822575_ChIP-Seq_HepG2_Human1.15270723
73NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.15095303
74CEBPB_22108803_ChIP-Seq_LS180_Human1.14419678
75TP63_22573176_ChIP-Seq_HFKS_Human1.14191058
76CLOCK_20551151_ChIP-Seq_293T_Human1.11802180
77RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11211036
78ESET_19884257_ChIP-Seq_ESCs_Mouse1.10889491
79BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.10822455
80AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.09980693
81JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09757283
82FOXA1_25552417_ChIP-Seq_VCAP_Human1.09291032
83PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.08222240
84CDX2_22108803_ChIP-Seq_LS180_Human1.08027450
85AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07441843
86FOXH1_21741376_ChIP-Seq_ESCs_Human1.07386280
87PPAR_26484153_Chip-Seq_NCI-H1993_Human1.07225712
88BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.07172647
89PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.06593419
90ERA_21632823_ChIP-Seq_H3396_Human1.06584175
91KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06296942
92RACK7_27058665_Chip-Seq_MCF-7_Human1.06228178
93ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.05184023
94SMAD_19615063_ChIP-ChIP_OVARY_Human1.03962788
95JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02091322
96SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.01974871
97HNF4A_19822575_ChIP-Seq_HepG2_Human1.01036520
98BCOR_27268052_Chip-Seq_Bcells_Human1.01017822
99ERG_20517297_ChIP-Seq_VCAP_Human1.00887014
100SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00839484
101GATA3_24758297_ChIP-Seq_MCF-7_Human1.00465458
102SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99921455
103NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98540268
104SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97467519
105ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97220815
106KLF5_25053715_ChIP-Seq_YYC3_Human0.96932110
107FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.94783891
108ZNF217_24962896_ChIP-Seq_MCF-7_Human0.94252623
109FOXA1_21572438_ChIP-Seq_LNCaP_Human0.94000049
110P53_21459846_ChIP-Seq_SAOS-2_Human0.93498974
111NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.93378235
112OCT4_20526341_ChIP-Seq_ESCs_Human0.93060658
113TBL1_22424771_ChIP-Seq_293T_Human0.92217042
114TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91819784
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90716321
116GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.90511772
117GATA3_21867929_ChIP-Seq_CD8_Mouse0.89067184
118GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.88850417
119ELK4_26923725_Chip-Seq_MESODERM_Mouse0.88291526
120PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.87628425
121EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.87415812
122FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.86000106
123CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85405930
124CTCF_20526341_ChIP-Seq_ESCs_Human0.85297259
125KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.85165687
126* CBP_21632823_ChIP-Seq_H3396_Human0.84679238
127CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84652330
128NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83012131
129SA1_27219007_Chip-Seq_Bcells_Human0.82993367
130FOXP1_21924763_ChIP-Seq_HESCs_Human0.82893512
131TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.82101277
132IRF1_19129219_ChIP-ChIP_H3396_Human0.82058763
133PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.81650079
134FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.81580668
135TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81415642
136SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.80774764
137* ETS1_21867929_ChIP-Seq_TH2_Mouse0.80713243
138CJUN_26792858_Chip-Seq_BT549_Human0.80211355
139SOX2_21211035_ChIP-Seq_LN229_Human0.79347797
140* TAF2_19829295_ChIP-Seq_ESCs_Human0.79232132
141RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.79188960
142AR_20517297_ChIP-Seq_VCAP_Human0.78675954
143SALL4_18804426_ChIP-ChIP_XEN_Mouse0.78421994
144Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.77847898
145KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.77121931
146FLI1_21867929_ChIP-Seq_CD8_Mouse0.77043447
147P300_27268052_Chip-Seq_Bcells_Human0.76805839
148JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.76662428
149ETV2_25802403_ChIP-Seq_MESCs_Mouse0.76451487
150LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.76199020
151TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.74700190

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005083_abnormal_biliary_tract9.32213740
2* MP0001666_abnormal_nutrient_absorption8.41194906
3MP0005365_abnormal_bile_salt6.62489344
4MP0005220_abnormal_exocrine_pancreas6.29415171
5MP0003868_abnormal_feces_composition5.07838354
6MP0005084_abnormal_gallbladder_morpholo5.03490021
7MP0005085_abnormal_gallbladder_physiolo3.65147262
8MP0001664_abnormal_digestion2.85978259
9MP0002693_abnormal_pancreas_physiology2.66246465
10MP0008004_abnormal_stomach_pH2.62236330
11MP0003959_abnormal_lean_body2.49992515
12MP0002139_abnormal_hepatobiliary_system2.40790481
13MP0004264_abnormal_extraembryonic_tissu2.13217554
14MP0009840_abnormal_foam_cell2.08155874
15MP0002138_abnormal_hepatobiliary_system2.06484443
16MP0004019_abnormal_vitamin_homeostasis2.03398553
17MP0010234_abnormal_vibrissa_follicle1.97838864
18MP0003705_abnormal_hypodermis_morpholog1.94260376
19MP0001944_abnormal_pancreas_morphology1.79867279
20MP0005448_abnormal_energy_balance1.73249449
21MP0010386_abnormal_urinary_bladder1.66898146
22MP0003252_abnormal_bile_duct1.56162392
23MP0003638_abnormal_response/metabolism_1.42947880
24MP0004233_abnormal_muscle_weight1.40481663
25MP0004147_increased_porphyrin_level1.33923778
26MP0002277_abnormal_respiratory_mucosa1.33258192
27MP0000470_abnormal_stomach_morphology1.31880401
28MP0005165_increased_susceptibility_to1.29542729
29MP0005332_abnormal_amino_acid1.28177140
30MP0001873_stomach_inflammation1.23916003
31* MP0002118_abnormal_lipid_homeostasis1.23401544
32MP0005451_abnormal_body_composition1.16788310
33MP0005360_urolithiasis1.11799300
34MP0003866_abnormal_defecation1.11088639
35MP0002928_abnormal_bile_duct1.09461922
36MP0002078_abnormal_glucose_homeostasis1.02785832
37MP0000490_abnormal_crypts_of0.96759277
38MP0010352_gastrointestinal_tract_polyps0.95199097
39MP0000538_abnormal_urinary_bladder0.93031426
40MP0005408_hypopigmentation0.90040984
41MP0003806_abnormal_nucleotide_metabolis0.89916549
42MP0009643_abnormal_urine_homeostasis0.89600846
43MP0003879_abnormal_hair_cell0.89312212
44MP0002132_abnormal_respiratory_system0.88312120
45MP0000003_abnormal_adipose_tissue0.87723046
46MP0001501_abnormal_sleep_pattern0.86487753
47MP0006054_spinal_hemorrhage0.84937891
48MP0003195_calcinosis0.84619801
49MP0001663_abnormal_digestive_system0.84110345
50MP0009384_cardiac_valve_regurgitation0.82863618
51MP0010329_abnormal_lipoprotein_level0.81728751
52MP0005166_decreased_susceptibility_to0.80808624
53MP0003953_abnormal_hormone_level0.79491385
54MP0005670_abnormal_white_adipose0.77961240
55MP0002163_abnormal_gland_morphology0.76762835
56MP0005535_abnormal_body_temperature0.76581967
57MP0009379_abnormal_foot_pigmentation0.74278635
58MP0008789_abnormal_olfactory_epithelium0.73264611
59MP0002822_catalepsy0.72010551
60MP0005381_digestive/alimentary_phenotyp0.71508045
61MP0000613_abnormal_salivary_gland0.68896742
62MP0008961_abnormal_basal_metabolism0.67812515
63MP0005058_abnormal_lysosome_morphology0.66570407
64MP0003045_fibrosis0.64983263
65MP0003300_gastrointestinal_ulcer0.64748215
66MP0002136_abnormal_kidney_physiology0.64607801
67MP0000477_abnormal_intestine_morphology0.63812143
68MP0005452_abnormal_adipose_tissue0.62338709
69MP0001764_abnormal_homeostasis0.61212412
70MP0000598_abnormal_liver_morphology0.60075254
71MP0003183_abnormal_peptide_metabolism0.56630747
72MP0002098_abnormal_vibrissa_morphology0.55659179
73MP0000609_abnormal_liver_physiology0.55419963
74MP0002909_abnormal_adrenal_gland0.55346386
75MP0002796_impaired_skin_barrier0.55181546
76MP0008438_abnormal_cutaneous_collagen0.55118002
77MP0003283_abnormal_digestive_organ0.55081529
78MP0006036_abnormal_mitochondrial_physio0.54655389
79MP0003186_abnormal_redox_activity0.54569178
80MP0005394_taste/olfaction_phenotype0.53532423
81MP0005499_abnormal_olfactory_system0.53532423
82MP0002876_abnormal_thyroid_physiology0.53165285
83MP0009780_abnormal_chondrocyte_physiolo0.52328371
84MP0005409_darkened_coat_color0.51739642
85MP0008260_abnormal_autophagy0.51008241
86MP0009765_abnormal_xenobiotic_induced0.50937728
87MP0002089_abnormal_postnatal_growth/wei0.50022535
88MP0008469_abnormal_protein_level0.48207627
89MP0002970_abnormal_white_adipose0.47528373
90MP0005319_abnormal_enzyme/_coenzyme0.47004677
91MP0002060_abnormal_skin_morphology0.44178890
92MP0001845_abnormal_inflammatory_respons0.43259083
93MP0005375_adipose_tissue_phenotype0.42593278
94MP0009764_decreased_sensitivity_to0.42014602
95MP0003943_abnormal_hepatobiliary_system0.40825582
96MP0004043_abnormal_pH_regulation0.40553611
97MP0005334_abnormal_fat_pad0.38634523
98MP0000377_abnormal_hair_follicle0.38579217
99MP0004185_abnormal_adipocyte_glucose0.38216629
100MP0010678_abnormal_skin_adnexa0.37325667
101MP0003656_abnormal_erythrocyte_physiolo0.36160127
102MP0000750_abnormal_muscle_regeneration0.35931080
103MP0000367_abnormal_coat/_hair0.35616616
104MP0001502_abnormal_circadian_rhythm0.34557197
105MP0003795_abnormal_bone_structure0.34552318
106MP0003011_delayed_dark_adaptation0.34385158
107MP0000462_abnormal_digestive_system0.34335301
108MP0009642_abnormal_blood_homeostasis0.34253078
109MP0004858_abnormal_nervous_system0.33810680
110MP0003718_maternal_effect0.33593043
111MP0005379_endocrine/exocrine_gland_phen0.33489612
112* MP0001731_abnormal_postnatal_growth0.33409439
113MP0001485_abnormal_pinna_reflex0.32849156
114MP0005187_abnormal_penis_morphology0.32737899
115MP0000371_diluted_coat_color0.32199953
116MP0003436_decreased_susceptibility_to0.31816511
117MP0003329_amyloid_beta_deposits0.31674494
118MP0000537_abnormal_urethra_morphology0.31526710
119MP0005501_abnormal_skin_physiology0.31026231
120MP0005584_abnormal_enzyme/coenzyme_acti0.30220441
121MP0000858_altered_metastatic_potential0.29738389
122MP0002896_abnormal_bone_mineralization0.29182347
123MP0002069_abnormal_eating/drinking_beha0.29166671
124MP0008872_abnormal_physiological_respon0.28823930
125MP0004484_altered_response_of0.28365333
126MP0000647_abnormal_sebaceous_gland0.27701946
127MP0005636_abnormal_mineral_homeostasis0.25523686
128MP0001756_abnormal_urination0.24992733
129MP0000566_synostosis0.24980160
130MP0001849_ear_inflammation0.24751607
131MP0009333_abnormal_splenocyte_physiolog0.23752598
132MP0003453_abnormal_keratinocyte_physiol0.23120160
133MP0010155_abnormal_intestine_physiology0.22761584
134MP0000579_abnormal_nail_morphology0.22564289
135MP0008875_abnormal_xenobiotic_pharmacok0.22179463
136MP0001765_abnormal_ion_homeostasis0.21890732

Predicted human phenotypes

RankGene SetZ-score
1Steatorrhea (HP:0002570)8.43674076
2Fat malabsorption (HP:0002630)7.32474911
3Abnormality of glutamine family amino acid metabolism (HP:0010902)7.06535470
4Gout (HP:0001997)6.80014489
5Hydroxyprolinuria (HP:0003080)6.38845491
6Abnormality of proline metabolism (HP:0010907)6.38845491
7Short chin (HP:0000331)5.49591232
8Decreased subcutaneous fat (HP:0001002)5.32632191
9Exocrine pancreatic insufficiency (HP:0001738)5.19333124
10Abnormality of subcutaneous fat tissue (HP:0001001)4.86424646
11Type I diabetes mellitus (HP:0100651)4.77166435
12Abnormal pancreas size (HP:0012094)4.69282228
13Tetraparesis (HP:0002273)4.60235562
14Ileus (HP:0002595)4.59734214
15Abnormality of the intrinsic pathway (HP:0010989)4.39753264
16Malnutrition (HP:0004395)4.35394830
17Hypoplasia of the pons (HP:0012110)4.18209400
18Maternal diabetes (HP:0009800)4.13699451
19Abnormality of the pons (HP:0007361)3.90856743
20Pancreatitis (HP:0001733)3.82428499
21Premature skin wrinkling (HP:0100678)3.65434055
22Abnormality of aromatic amino acid family metabolism (HP:0004338)3.58138919
23Ketosis (HP:0001946)3.57686209
24Ketoacidosis (HP:0001993)3.53700935
25Tubulointerstitial fibrosis (HP:0005576)3.49319584
26Tubulointerstitial nephritis (HP:0001970)3.44606816
27Cortical dysplasia (HP:0002539)3.41652896
28Carpal bone hypoplasia (HP:0001498)3.38961716
29Joint stiffness (HP:0001387)3.28752224
30Hypoproteinemia (HP:0003075)3.28320661
31Increased purine levels (HP:0004368)3.22058577
32Hyperuricemia (HP:0002149)3.22058577
33Abnormality of endocrine pancreas physiology (HP:0012093)3.14646908
34Abnormality of the pancreatic islet cells (HP:0006476)3.14646908
35Hyperglycinemia (HP:0002154)3.08152056
36Hypoglycemic coma (HP:0001325)3.02048127
37Abnormality of the pleura (HP:0002103)3.00289495
38Hyperglycinuria (HP:0003108)2.98068255
39Ventricular fibrillation (HP:0001663)2.97546876
40Long foot (HP:0001833)2.94458952
41Abnormality of sulfur amino acid metabolism (HP:0004339)2.90036260
42Abnormal tarsal ossification (HP:0008369)2.82412196
43Abnormality of vitamin B metabolism (HP:0004340)2.78810588
44Right ventricular cardiomyopathy (HP:0011663)2.76468469
45Vascular calcification (HP:0004934)2.74819335
46Hypobetalipoproteinemia (HP:0003563)2.72063913
47Late onset (HP:0003584)2.71259231
48Abnormality of glycine metabolism (HP:0010895)2.71051036
49Abnormality of serine family amino acid metabolism (HP:0010894)2.71051036
50Abnormality of the common coagulation pathway (HP:0010990)2.70647879
51Hypoglycemic seizures (HP:0002173)2.60670969
52Villous atrophy (HP:0011473)2.59807245
53Abnormality of small intestinal villus morphology (HP:0011472)2.59807245
54Abnormal protein glycosylation (HP:0012346)2.56215590
55Abnormal glycosylation (HP:0012345)2.56215590
56Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.56215590
57Abnormal protein N-linked glycosylation (HP:0012347)2.56215590
58Abnormality of urine glucose concentration (HP:0011016)2.53363678
59Glycosuria (HP:0003076)2.53363678
60Rectal prolapse (HP:0002035)2.50185185
61Abnormality of vitamin metabolism (HP:0100508)2.48111056
62Fatigue (HP:0012378)2.47624214
63Abnormal biliary tract morphology (HP:0012440)2.47458130
64Progressive muscle weakness (HP:0003323)2.45394870
65Conjugated hyperbilirubinemia (HP:0002908)2.42352699
66Cardiovascular calcification (HP:0011915)2.37725473
67Prenatal maternal abnormality (HP:0002686)2.35936123
68Paraparesis (HP:0002385)2.34050021
69Hypoplasia of the uterus (HP:0000013)2.33369817
70Hyperinsulinemic hypoglycemia (HP:0000825)2.32103786
71Optic nerve hypoplasia (HP:0000609)2.31811278
72Megaloblastic anemia (HP:0001889)2.31324607
73Small epiphyses (HP:0010585)2.29820426
74Esophageal varix (HP:0002040)2.29467171
75Abnormality of purine metabolism (HP:0004352)2.25470990
76Acute hepatic failure (HP:0006554)2.25196449
77Proximal tubulopathy (HP:0000114)2.24788775
78Hypoplasia of the odontoid process (HP:0003311)2.20352497
79Vacuolated lymphocytes (HP:0001922)2.19465728
80Pectus carinatum (HP:0000768)2.19129243
81Male infertility (HP:0003251)2.18717057
82Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.17306646
83Chronic diarrhea (HP:0002028)2.17000781
84Abnormal number of erythroid precursors (HP:0012131)2.16232711
85Congenital glaucoma (HP:0001087)2.15792529
86Congenital malformation of the right heart (HP:0011723)2.15565982
87Double outlet right ventricle (HP:0001719)2.15565982
88Widely patent fontanelles and sutures (HP:0004492)2.12980020
89Abnormality of the renal cortex (HP:0011035)2.12964763
90Abnormality of cells of the erythroid lineage (HP:0012130)2.12043968
91Xanthomatosis (HP:0000991)2.11099411
92Hyperglycemia (HP:0003074)2.10190894
93Hyperphosphatemia (HP:0002905)2.09756355
94Barrel-shaped chest (HP:0001552)2.08886782
95Prolonged QT interval (HP:0001657)2.08617795
96Sex reversal (HP:0012245)2.07115856
97Abnormal sex determination (HP:0012244)2.07115856
98Abnormal foot bone ossification (HP:0010675)2.06524902
99Reduced antithrombin III activity (HP:0001976)2.06253262
100Ankyloglossia (HP:0010296)2.04400714
101Dysostosis multiplex (HP:0000943)2.04253636
102Tubular atrophy (HP:0000092)2.02695419
103Abnormality of monocarboxylic acid metabolism (HP:0010996)2.02179195
104Systemic lupus erythematosus (HP:0002725)2.01107843
105Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.00917507
106Pigmentary retinal degeneration (HP:0001146)2.00162850
107Myocardial infarction (HP:0001658)2.00086558
108Congenital sensorineural hearing impairment (HP:0008527)1.99847628
109Methylmalonic aciduria (HP:0012120)1.98031550
110Type I transferrin isoform profile (HP:0003642)1.95760855
111Abnormality of aspartate family amino acid metabolism (HP:0010899)1.95117748
112Abnormality of methionine metabolism (HP:0010901)1.94653304
113Anal atresia (HP:0002023)1.93831917
114Tubulointerstitial abnormality (HP:0001969)1.93516471
115Cortical visual impairment (HP:0100704)1.92628446
116Flat acetabular roof (HP:0003180)1.89139978
117Abnormality of homocysteine metabolism (HP:0010919)1.89064127
118Homocystinuria (HP:0002156)1.89064127
119Severe short stature (HP:0003510)1.86142580
120Vertebral compression fractures (HP:0002953)1.85577776
121Popliteal pterygium (HP:0009756)1.83437431
122Syncope (HP:0001279)1.83275861
123Lower limb hyperreflexia (HP:0002395)1.82937307
124Flattened epiphyses (HP:0003071)1.82842785
125Symptomatic seizures (HP:0011145)1.82453007
126Intrahepatic cholestasis (HP:0001406)1.81781695
127Renal salt wasting (HP:0000127)1.81702460
128Opisthotonus (HP:0002179)1.81071382
129Type II lissencephaly (HP:0007260)1.80241703
130Abdominal distention (HP:0003270)1.80087798
131Potter facies (HP:0002009)1.79448304
132Facial shape deformation (HP:0011334)1.79448304
133Acanthocytosis (HP:0001927)1.78402738
134Nausea (HP:0002018)1.77951893
135Progressive sensorineural hearing impairment (HP:0000408)1.77824757
136Limb hypertonia (HP:0002509)1.77583821
137Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.77352818
138Hyperammonemia (HP:0001987)1.76547343
139Glomerulosclerosis (HP:0000096)1.76494857
140Abnormality of the vitamin B12 metabolism (HP:0004341)1.76403743
141Atrophic scars (HP:0001075)1.75824357
142Abnormality of alkaline phosphatase activity (HP:0004379)1.73586971
143Dehydration (HP:0001944)1.69868166
144Abnormal enzyme/coenzyme activity (HP:0012379)1.68893114
145Nephrolithiasis (HP:0000787)1.68349205
146Insulin-resistant diabetes mellitus (HP:0000831)1.66653577
147Confusion (HP:0001289)1.66177027
148Wide cranial sutures (HP:0010537)1.63963040
149Large for gestational age (HP:0001520)1.63088954
150Subcapsular cataract (HP:0000523)1.62339763
151Metabolic acidosis (HP:0001942)1.62274751
152Abdominal pain (HP:0002027)1.62065757
153Renal tubular acidosis (HP:0001947)1.61751738
154Glomerulonephritis (HP:0000099)1.57953525
155Gastrointestinal dysmotility (HP:0002579)1.57720432
156Decreased circulating renin level (HP:0003351)1.57382784
157Increased CSF protein (HP:0002922)1.56858774
158Elevated alkaline phosphatase (HP:0003155)1.56447896
159Hypercalciuria (HP:0002150)1.51439464
160Hypophosphatemia (HP:0002148)1.47108339
161Abnormality of chloride homeostasis (HP:0011422)1.46690127
162Hypolipoproteinemia (HP:0010981)1.46096257
163Abnormality of fatty-acid metabolism (HP:0004359)1.45859099

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK9.40604721
2ERN15.23489687
3EIF2AK34.63139473
4MAP2K24.29313630
5ACVR1B3.39959942
6TRIB33.17142157
7FRK2.99830029
8PKN22.80327371
9PRKG22.67530672
10INSRR2.64326268
11MAP3K122.15196202
12MAPKAPK32.01968325
13TAOK31.92490996
14IRAK31.90293675
15ZAP701.88108503
16NME11.82872825
17MAPK151.76502963
18MAP2K11.73787251
19GRK11.67900101
20EIF2AK11.63379806
21PAK21.53828042
22SCYL21.51412707
23WNK41.35537810
24NME21.34450858
25PTK61.29391378
26CDK191.24911501
27RPS6KB21.22936117
28DYRK1A1.15606000
29MAP3K21.13181036
30NLK1.11590522
31PDGFRB1.10251439
32EEF2K1.05466660
33TESK11.05188274
34PIK3CG1.03054939
35PIK3CA1.02619551
36ERBB40.98744938
37LATS10.97186275
38PDK20.94570501
39FLT30.94311862
40MST1R0.93764996
41OXSR10.93336820
42EPHA20.91147674
43NTRK30.83857457
44CAMKK10.81522118
45MAP2K60.81012413
46PRKCI0.78466969
47SIK10.77400155
48MYLK0.76756596
49TAOK10.72322513
50BMPR1B0.69068030
51DYRK1B0.67685303
52MTOR0.67625029
53STK390.64587931
54IRAK20.64236843
55RIPK10.63861023
56STK240.60000112
57CAMKK20.59316150
58LMTK20.58510734
59STK160.58246909
60FER0.57446011
61FGFR30.57308768
62LRRK20.57079824
63DAPK20.57071860
64PDPK10.54460567
65TAOK20.53815999
66RET0.52885246
67MET0.51589375
68MAP3K50.51051400
69KSR20.49439899
70MAP3K110.49138202
71PRKCZ0.46934679
72EPHB10.46215528
73MAP3K100.45786869
74MAP3K10.45452718
75RPS6KB10.45338675
76TSSK60.43041599
77MAP3K90.42766932
78JAK10.41585403
79PINK10.41377684
80DAPK10.40742948
81IRAK40.40638752
82PRKCE0.40367446
83PTK20.39642101
84TRPM70.39346540
85PDK10.39127723
86PDK30.39100259
87PDK40.39100259
88BCR0.35255221
89FGFR40.35250272
90MAP3K30.34235506
91PRKCA0.33974935
92PRKCH0.33035534
93ERBB30.32778276
94PRKACG0.32537061
95NTRK10.31873274
96MAP3K70.31136137
97MAPK120.30691015
98MAP3K140.30085440
99ROCK10.29305872
100MAPK30.28947239
101PRKACB0.28166086
102NEK60.27975323
103IRAK10.27889048
104RPS6KA10.27051101
105DDR20.26973263
106MAPK70.26643527
107PRKD30.26393475
108MAP3K80.25159935
109EPHA30.24959882
110PDGFRA0.24875042
111NUAK10.24819820
112JAK20.24409830
113PRKAA20.24245507
114MELK0.22235394
115TIE10.21937361
116GRK60.21489988
117ABL10.20905279
118TBK10.20893066
119NEK10.20516626
120PRKD10.20338415
121BMPR20.20058947
122YES10.18138704
123ILK0.16996089
124PIM10.16094201
125STK380.15782528
126CAMK40.14583394
127CSNK1E0.14464040
128IGF1R0.13983693
129DAPK30.13913916
130MAPK10.13905504
131IKBKE0.13528038
132TYK20.13347088
133CSNK1A10.13308524
134PRKACA0.13220839
135CAMK2G0.13053528
136GSK3A0.12441271
137AKT30.12364161
138PIM20.12025566
139MAPK110.11684617
140SRC0.11244029
141MATK0.11206656
142PRKAA10.11047907
143PAK40.10836779
144ERBB20.10691624
145PRKCD0.10287988
146DYRK20.09467545
147HIPK20.09020798
148MST40.08147165
149PASK0.07668186
150EGFR0.07419402
151CAMK1D0.07188254

Predicted pathways (KEGG)

RankGene SetZ-score
1* Pancreatic secretion_Homo sapiens_hsa049728.04891133
2Protein digestion and absorption_Homo sapiens_hsa049745.75351229
3* Fat digestion and absorption_Homo sapiens_hsa049755.48583959
4Maturity onset diabetes of the young_Homo sapiens_hsa049503.50080225
5Protein export_Homo sapiens_hsa030603.28618520
6Folate biosynthesis_Homo sapiens_hsa007903.09762804
7Vitamin digestion and absorption_Homo sapiens_hsa049772.64727614
8Cyanoamino acid metabolism_Homo sapiens_hsa004602.61352230
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.36620520
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.27803411
11* Glycerolipid metabolism_Homo sapiens_hsa005612.13490057
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.12486506
13Renin-angiotensin system_Homo sapiens_hsa046141.94502200
14Steroid biosynthesis_Homo sapiens_hsa001001.88803349
15Propanoate metabolism_Homo sapiens_hsa006401.72151192
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.50003833
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.44425043
18Linoleic acid metabolism_Homo sapiens_hsa005911.43716356
19Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.18768273
20Arginine and proline metabolism_Homo sapiens_hsa003301.16200540
212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.14868888
22Carbohydrate digestion and absorption_Homo sapiens_hsa049731.10117450
23Starch and sucrose metabolism_Homo sapiens_hsa005001.10101390
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00879817
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96341417
26Biosynthesis of amino acids_Homo sapiens_hsa012300.95629627
27N-Glycan biosynthesis_Homo sapiens_hsa005100.94273316
28Steroid hormone biosynthesis_Homo sapiens_hsa001400.89511483
29Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86432561
30Other glycan degradation_Homo sapiens_hsa005110.84217705
31Sulfur metabolism_Homo sapiens_hsa009200.82875169
32Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78374063
33Selenocompound metabolism_Homo sapiens_hsa004500.78155084
34Cysteine and methionine metabolism_Homo sapiens_hsa002700.75342797
35Influenza A_Homo sapiens_hsa051640.73260202
36Retinol metabolism_Homo sapiens_hsa008300.73220027
37Insulin secretion_Homo sapiens_hsa049110.71407583
38Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69922766
39Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.69536582
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.69277809
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68142104
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63262103
43Vibrio cholerae infection_Homo sapiens_hsa051100.63156977
44beta-Alanine metabolism_Homo sapiens_hsa004100.62356664
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61339601
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59766909
47Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.59542963
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57924359
49Fructose and mannose metabolism_Homo sapiens_hsa000510.57848284
50One carbon pool by folate_Homo sapiens_hsa006700.57792947
51Notch signaling pathway_Homo sapiens_hsa043300.57688002
52Glutathione metabolism_Homo sapiens_hsa004800.56562025
53Fatty acid degradation_Homo sapiens_hsa000710.55212421
54Arachidonic acid metabolism_Homo sapiens_hsa005900.55194766
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52367983
56Caffeine metabolism_Homo sapiens_hsa002320.51279572
57Pyruvate metabolism_Homo sapiens_hsa006200.51115133
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49337104
59Ether lipid metabolism_Homo sapiens_hsa005650.46296730
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.45913396
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.43269133
62Tryptophan metabolism_Homo sapiens_hsa003800.40719516
63Arginine biosynthesis_Homo sapiens_hsa002200.39612950
64Legionellosis_Homo sapiens_hsa051340.38511518
65Sphingolipid metabolism_Homo sapiens_hsa006000.38475800
66Vitamin B6 metabolism_Homo sapiens_hsa007500.36078811
67PPAR signaling pathway_Homo sapiens_hsa033200.35073518
68Carbon metabolism_Homo sapiens_hsa012000.34088103
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33408350
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33056984
71Regulation of autophagy_Homo sapiens_hsa041400.32733329
72Glycerophospholipid metabolism_Homo sapiens_hsa005640.30595969
73* Metabolic pathways_Homo sapiens_hsa011000.29172672
74Galactose metabolism_Homo sapiens_hsa000520.28882508
75Gastric acid secretion_Homo sapiens_hsa049710.27441683
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26202393
77Lysosome_Homo sapiens_hsa041420.26136779
78Endometrial cancer_Homo sapiens_hsa052130.26131390
79Mineral absorption_Homo sapiens_hsa049780.25204235
80Bile secretion_Homo sapiens_hsa049760.24252951
81Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.23435806
82Sulfur relay system_Homo sapiens_hsa041220.21608438
83Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.20025502
84Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19485412
85Nitrogen metabolism_Homo sapiens_hsa009100.19141942
86Histidine metabolism_Homo sapiens_hsa003400.18420920
87Circadian rhythm_Homo sapiens_hsa047100.17773415
88Alzheimers disease_Homo sapiens_hsa050100.17562137
89Hepatitis C_Homo sapiens_hsa051600.17438866
90Thyroid hormone synthesis_Homo sapiens_hsa049180.17165929
91VEGF signaling pathway_Homo sapiens_hsa043700.16832894
92Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.16500226
93Pentose phosphate pathway_Homo sapiens_hsa000300.16387453
94Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.15111412
95ABC transporters_Homo sapiens_hsa020100.14993064
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.14931961
97Chemical carcinogenesis_Homo sapiens_hsa052040.13947569
98Fatty acid metabolism_Homo sapiens_hsa012120.13002394
99Parkinsons disease_Homo sapiens_hsa050120.10846722
100Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.10470540
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.08495410
102Insulin resistance_Homo sapiens_hsa049310.08258770
103Tyrosine metabolism_Homo sapiens_hsa003500.06594357
104Phenylalanine metabolism_Homo sapiens_hsa003600.06216017
105Calcium signaling pathway_Homo sapiens_hsa040200.06019895
106Prostate cancer_Homo sapiens_hsa052150.06017887
107mTOR signaling pathway_Homo sapiens_hsa041500.05859006
108Tight junction_Homo sapiens_hsa045300.05429555
109Vascular smooth muscle contraction_Homo sapiens_hsa042700.05210507
110Ovarian steroidogenesis_Homo sapiens_hsa049130.04001114
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.03875920
112Peroxisome_Homo sapiens_hsa041460.03267603
113Toxoplasmosis_Homo sapiens_hsa051450.03261285
114Bladder cancer_Homo sapiens_hsa052190.03007791
115Complement and coagulation cascades_Homo sapiens_hsa046100.01889021
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.01667055
117Butanoate metabolism_Homo sapiens_hsa006500.00893727
118Fatty acid elongation_Homo sapiens_hsa00062-0.1114321
119Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960-0.1089181
120TNF signaling pathway_Homo sapiens_hsa04668-0.0917275
121Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060-0.0773354
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514-0.0703555
123Asthma_Homo sapiens_hsa05310-0.0598595
124Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.0532934
125Leukocyte transendothelial migration_Homo sapiens_hsa04670-0.0372040
126Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760-0.0349706
127Cocaine addiction_Homo sapiens_hsa05030-0.0145558
128Type I diabetes mellitus_Homo sapiens_hsa04940-0.0051985
129Oxidative phosphorylation_Homo sapiens_hsa00190-0.0030292

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