Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.89092421 |
2 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.89092421 |
3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.54108308 |
4 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.40409845 |
5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.09643581 |
6 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 4.67885736 |
7 | response to peptidoglycan (GO:0032494) | 4.54837575 |
8 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.30310546 |
9 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.23391430 |
10 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.23391430 |
11 | modulation by symbiont of host immune response (GO:0052553) | 4.23391430 |
12 | positive regulation by symbiont of host defense response (GO:0052509) | 4.23391430 |
13 | modulation by symbiont of host defense response (GO:0052031) | 4.23391430 |
14 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.23391430 |
15 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.22277956 |
16 | tolerance induction (GO:0002507) | 4.16156668 |
17 | macrophage activation involved in immune response (GO:0002281) | 4.13709722 |
18 | NIK/NF-kappaB signaling (GO:0038061) | 4.12640654 |
19 | negative regulation of interleukin-12 production (GO:0032695) | 4.12572566 |
20 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.09023353 |
21 | regulation of gamma-delta T cell activation (GO:0046643) | 4.05578634 |
22 | response to muramyl dipeptide (GO:0032495) | 4.00496497 |
23 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.83720971 |
24 | interferon-gamma production (GO:0032609) | 3.76907062 |
25 | detection of other organism (GO:0098543) | 3.74561207 |
26 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.70301353 |
27 | detection of bacterium (GO:0016045) | 3.55079228 |
28 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.53173541 |
29 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.53146170 |
30 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.51032948 |
31 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.50155760 |
32 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.49459120 |
33 | germinal center formation (GO:0002467) | 3.48292838 |
34 | positive regulation of B cell differentiation (GO:0045579) | 3.46355507 |
35 | negative T cell selection (GO:0043383) | 3.37017439 |
36 | response to type I interferon (GO:0034340) | 3.33759906 |
37 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.33501681 |
38 | positive thymic T cell selection (GO:0045059) | 3.32708475 |
39 | regulation of B cell differentiation (GO:0045577) | 3.32527248 |
40 | type I interferon signaling pathway (GO:0060337) | 3.31389190 |
41 | cellular response to type I interferon (GO:0071357) | 3.31389190 |
42 | microglial cell activation (GO:0001774) | 3.30242201 |
43 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.27425297 |
44 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.27063769 |
45 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.26829166 |
46 | detection of molecule of bacterial origin (GO:0032490) | 3.26023658 |
47 | detection of external biotic stimulus (GO:0098581) | 3.25257800 |
48 | negative thymic T cell selection (GO:0045060) | 3.22034038 |
49 | response to host immune response (GO:0052572) | 3.21439162 |
50 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.21439162 |
51 | immunoglobulin mediated immune response (GO:0016064) | 3.21251185 |
52 | myeloid dendritic cell activation (GO:0001773) | 3.17905901 |
53 | macrophage activation (GO:0042116) | 3.17632424 |
54 | leukocyte aggregation (GO:0070486) | 3.14660204 |
55 | myeloid dendritic cell differentiation (GO:0043011) | 3.13245080 |
56 | regulation of interferon-alpha production (GO:0032647) | 3.13086588 |
57 | response to interleukin-15 (GO:0070672) | 3.11658618 |
58 | T cell migration (GO:0072678) | 3.11554530 |
59 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.08276878 |
60 | T-helper cell differentiation (GO:0042093) | 3.08276878 |
61 | negative regulation of T cell mediated immunity (GO:0002710) | 3.07606376 |
62 | T-helper 1 type immune response (GO:0042088) | 3.04979098 |
63 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.03303620 |
64 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.02186076 |
65 | B cell receptor signaling pathway (GO:0050853) | 3.01144514 |
66 | positive regulation of interferon-alpha production (GO:0032727) | 2.98505270 |
67 | regulation of natural killer cell differentiation (GO:0032823) | 2.97486644 |
68 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.96894132 |
69 | response to host (GO:0075136) | 2.96894132 |
70 | response to host defenses (GO:0052200) | 2.96894132 |
71 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.96709283 |
72 | thymic T cell selection (GO:0045061) | 2.95256194 |
73 | regulation of antigen processing and presentation (GO:0002577) | 2.94972001 |
74 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.93985753 |
75 | myeloid cell activation involved in immune response (GO:0002275) | 2.93933957 |
76 | detection of biotic stimulus (GO:0009595) | 2.91989395 |
77 | regulation of tolerance induction (GO:0002643) | 2.91645196 |
78 | positive regulation of type 2 immune response (GO:0002830) | 2.89309646 |
79 | neutrophil mediated immunity (GO:0002446) | 2.88076964 |
80 | granulocyte activation (GO:0036230) | 2.87802789 |
81 | regulation of response to interferon-gamma (GO:0060330) | 2.86209842 |
82 | T cell selection (GO:0045058) | 2.86057858 |
83 | hepatocyte apoptotic process (GO:0097284) | 2.84950912 |
84 | lymph node development (GO:0048535) | 2.84634228 |
85 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.83809929 |
86 | regulation of germinal center formation (GO:0002634) | 2.83412223 |
87 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.82923450 |
88 | negative regulation of cell killing (GO:0031342) | 2.82923450 |
89 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.81442892 |
90 | regulation of mast cell degranulation (GO:0043304) | 2.81112186 |
91 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.80307511 |
92 | neutrophil activation involved in immune response (GO:0002283) | 2.77715278 |
93 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.77340276 |
94 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.77298655 |
95 | positive regulation of interleukin-2 production (GO:0032743) | 2.76102157 |
96 | positive regulation of tolerance induction (GO:0002645) | 2.74879267 |
97 | response to protozoan (GO:0001562) | 2.74712516 |
98 | negative regulation of interleukin-6 production (GO:0032715) | 2.74549642 |
99 | positive T cell selection (GO:0043368) | 2.73968659 |
100 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.73879145 |
101 | positive regulation of isotype switching (GO:0045830) | 2.73585743 |
102 | regulation of T cell tolerance induction (GO:0002664) | 2.73419064 |
103 | regulation of necroptotic process (GO:0060544) | 2.72681361 |
104 | JAK-STAT cascade (GO:0007259) | 2.71372922 |
105 | definitive hemopoiesis (GO:0060216) | 2.70476903 |
106 | cellular response to interleukin-15 (GO:0071350) | 2.70092328 |
107 | regulation of RIG-I signaling pathway (GO:0039535) | 2.69338769 |
108 | regulation of interleukin-12 production (GO:0032655) | 2.68504521 |
109 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.68326247 |
110 | negative regulation of innate immune response (GO:0045824) | 2.67953050 |
111 | T cell differentiation involved in immune response (GO:0002292) | 2.67604283 |
112 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.67604283 |
113 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.67604283 |
114 | alpha-beta T cell activation (GO:0046631) | 2.67540770 |
115 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.67470213 |
116 | natural killer cell differentiation (GO:0001779) | 2.66627640 |
117 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.66599000 |
118 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.65946924 |
119 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.65808638 |
120 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.65580046 |
121 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.65051638 |
122 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.64651850 |
123 | mature B cell differentiation (GO:0002335) | 2.64452944 |
124 | cellular extravasation (GO:0045123) | 2.62796652 |
125 | lymphocyte homeostasis (GO:0002260) | 2.62217208 |
126 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 2.62150253 |
127 | embryonic process involved in female pregnancy (GO:0060136) | 2.61511327 |
128 | positive regulation of interferon-beta production (GO:0032728) | 2.61336580 |
129 | leukocyte homeostasis (GO:0001776) | 2.60308918 |
130 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.60248567 |
131 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.60210286 |
132 | regulation of type 2 immune response (GO:0002828) | 2.60205331 |
133 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.58610347 |
134 | dendritic cell differentiation (GO:0097028) | 2.58084164 |
135 | cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) | 2.56376233 |
136 | T cell activation involved in immune response (GO:0002286) | 2.55297785 |
137 | T cell homeostasis (GO:0043029) | 2.54710084 |
138 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.53810987 |
139 | alpha-beta T cell differentiation (GO:0046632) | 2.53370458 |
140 | natural killer cell activation (GO:0030101) | 2.53146697 |
141 | defense response to protozoan (GO:0042832) | 2.53033012 |
142 | T cell lineage commitment (GO:0002360) | 2.52877356 |
143 | T cell differentiation (GO:0030217) | 2.52339262 |
144 | leukocyte cell-cell adhesion (GO:0007159) | 2.52106561 |
145 | positive regulation of DNA recombination (GO:0045911) | 2.51713352 |
146 | mature B cell differentiation involved in immune response (GO:0002313) | 2.50831038 |
147 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.50676957 |
148 | B cell homeostasis (GO:0001782) | 2.50408060 |
149 | positive regulation of macrophage differentiation (GO:0045651) | 2.50373936 |
150 | positive regulation of B cell mediated immunity (GO:0002714) | 2.49300671 |
151 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.49300671 |
152 | neutrophil activation (GO:0042119) | 2.49079491 |
153 | regulation of chronic inflammatory response (GO:0002676) | 2.48949637 |
154 | megakaryocyte development (GO:0035855) | 2.47704093 |
155 | positive regulation of humoral immune response (GO:0002922) | 2.45829480 |
156 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.43855011 |
157 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.42883773 |
158 | positive regulation of antigen processing and presentation (GO:0002579) | 2.42564365 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.15344894 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.03847571 |
3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.38002777 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.56505026 |
5 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.28871626 |
6 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.19957384 |
7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.15171093 |
8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.13515666 |
9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.04630721 |
10 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.96453094 |
11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.92941291 |
12 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.75141589 |
13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.72095945 |
14 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.70667864 |
15 | * IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.70330330 |
16 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.60597333 |
17 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.58712512 |
18 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.54113369 |
19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.52762955 |
20 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.50253640 |
21 | MYB_26560356_Chip-Seq_TH2_Human | 2.49721045 |
22 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.42703868 |
23 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.40664025 |
24 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.33250684 |
25 | MAF_26560356_Chip-Seq_TH1_Human | 2.31039188 |
26 | MYC_22102868_ChIP-Seq_BL_Human | 2.27576943 |
27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.26876039 |
28 | MYB_26560356_Chip-Seq_TH1_Human | 2.17195087 |
29 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 2.04474252 |
30 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.02107090 |
31 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.93440364 |
32 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.89504003 |
33 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.86654878 |
34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.84763652 |
35 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.84100063 |
36 | GATA1_22025678_ChIP-Seq_K562_Human | 1.83426073 |
37 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.79683804 |
38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.73914807 |
39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.73362134 |
40 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.69152844 |
41 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.68004630 |
42 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63840323 |
43 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.61348958 |
44 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.57514867 |
45 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.57224195 |
46 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.55701361 |
47 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55173593 |
48 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.52015598 |
49 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.44245459 |
50 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.43182381 |
51 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41293671 |
52 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.41196478 |
53 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.40052872 |
54 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.40024898 |
55 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.38552774 |
56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37597025 |
57 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.37253315 |
58 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.36606401 |
59 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36430645 |
60 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.34657943 |
61 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.33209162 |
62 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.31804654 |
63 | MAF_26560356_Chip-Seq_TH2_Human | 1.31124751 |
64 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.25111945 |
65 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.24920183 |
66 | SPI1_23127762_ChIP-Seq_K562_Human | 1.24687836 |
67 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.21541978 |
68 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.20201218 |
69 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17425484 |
70 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.15158414 |
71 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.14332266 |
72 | GATA1_19941826_ChIP-Seq_K562_Human | 1.13717659 |
73 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.12291121 |
74 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.10885560 |
75 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10052903 |
76 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.09369889 |
77 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09155748 |
78 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08183803 |
79 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07238378 |
80 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.06589061 |
81 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04595965 |
82 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04468950 |
83 | GATA2_19941826_ChIP-Seq_K562_Human | 1.04163931 |
84 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03302615 |
85 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.02462593 |
86 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.02165252 |
87 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.02062311 |
88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00769658 |
89 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98139624 |
90 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.96568632 |
91 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.96498283 |
92 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96398092 |
93 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.95797304 |
94 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.92815984 |
95 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92761867 |
96 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91739290 |
97 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.90694101 |
98 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.90336832 |
99 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.88888939 |
100 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88188077 |
101 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.87998572 |
102 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.86841486 |
103 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.85449263 |
104 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.85030187 |
105 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.84382148 |
106 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.84286798 |
107 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.84002271 |
108 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.84002271 |
109 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.84002271 |
110 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.83259507 |
111 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.81775908 |
112 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.81721785 |
113 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.81250146 |
114 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.80606757 |
115 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.80386068 |
116 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.79678316 |
117 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.75041704 |
118 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.72461513 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.45423186 |
2 | MP0000685_abnormal_immune_system | 3.20581345 |
3 | MP0003724_increased_susceptibility_to | 2.99012006 |
4 | MP0005671_abnormal_response_to | 2.91500572 |
5 | MP0003763_abnormal_thymus_physiology | 2.89771272 |
6 | MP0009785_altered_susceptibility_to | 2.85621273 |
7 | MP0003436_decreased_susceptibility_to | 2.79964763 |
8 | MP0002166_altered_tumor_susceptibility | 2.73913402 |
9 | MP0005000_abnormal_immune_tolerance | 2.55714169 |
10 | MP0001800_abnormal_humoral_immune | 2.50483966 |
11 | MP0005387_immune_system_phenotype | 2.47650693 |
12 | MP0001790_abnormal_immune_system | 2.47650693 |
13 | MP0002006_tumorigenesis | 2.31523768 |
14 | MP0005025_abnormal_response_to | 2.29692907 |
15 | MP0002723_abnormal_immune_serum | 2.29632671 |
16 | MP0002452_abnormal_antigen_presenting | 2.26011391 |
17 | MP0002148_abnormal_hypersensitivity_rea | 2.23862367 |
18 | MP0001873_stomach_inflammation | 2.22199237 |
19 | MP0010155_abnormal_intestine_physiology | 2.14168630 |
20 | MP0002420_abnormal_adaptive_immunity | 2.13282763 |
21 | MP0001819_abnormal_immune_cell | 2.12210818 |
22 | MP0004947_skin_inflammation | 2.11744561 |
23 | MP0002419_abnormal_innate_immunity | 2.08188873 |
24 | MP0002405_respiratory_system_inflammati | 2.07164455 |
25 | MP0002138_abnormal_hepatobiliary_system | 2.05830400 |
26 | MP0003300_gastrointestinal_ulcer | 1.98624803 |
27 | MP0004510_myositis | 1.94841500 |
28 | MP0002009_preneoplasia | 1.91157346 |
29 | MP0008004_abnormal_stomach_pH | 1.88762538 |
30 | MP0002398_abnormal_bone_marrow | 1.87902556 |
31 | MP0006082_CNS_inflammation | 1.86576907 |
32 | MP0003303_peritoneal_inflammation | 1.81591481 |
33 | MP0009333_abnormal_splenocyte_physiolog | 1.80665119 |
34 | MP0005464_abnormal_platelet_physiology | 1.76905188 |
35 | MP0000716_abnormal_immune_system | 1.76661737 |
36 | MP0001845_abnormal_inflammatory_respons | 1.72652389 |
37 | MP0001853_heart_inflammation | 1.65638065 |
38 | MP0005451_abnormal_body_composition | 1.64853048 |
39 | MP0001545_abnormal_hematopoietic_system | 1.63174378 |
40 | MP0005397_hematopoietic_system_phenotyp | 1.63174378 |
41 | MP0002254_reproductive_system_inflammat | 1.61288385 |
42 | MP0002396_abnormal_hematopoietic_system | 1.59775694 |
43 | MP0004808_abnormal_hematopoietic_stem | 1.57279441 |
44 | MP0000689_abnormal_spleen_morphology | 1.55028101 |
45 | MP0009278_abnormal_bone_marrow | 1.54084036 |
46 | MP0002722_abnormal_immune_system | 1.51145310 |
47 | MP0001533_abnormal_skeleton_physiology | 1.48721129 |
48 | MP0002429_abnormal_blood_cell | 1.47035187 |
49 | MP0003866_abnormal_defecation | 1.46850956 |
50 | MP0005310_abnormal_salivary_gland | 1.44180021 |
51 | MP0002933_joint_inflammation | 1.40996097 |
52 | MP0003172_abnormal_lysosome_physiology | 1.40729470 |
53 | MP0000858_altered_metastatic_potential | 1.37118669 |
54 | MP0008469_abnormal_protein_level | 1.36093998 |
55 | MP0001851_eye_inflammation | 1.34267621 |
56 | MP0002877_abnormal_melanocyte_morpholog | 1.33912407 |
57 | MP0000703_abnormal_thymus_morphology | 1.32347286 |
58 | MP0009764_decreased_sensitivity_to | 1.30470076 |
59 | MP0000490_abnormal_crypts_of | 1.29677864 |
60 | MP0003828_pulmonary_edema | 1.29589920 |
61 | MP0000465_gastrointestinal_hemorrhage | 1.28960858 |
62 | MP0010352_gastrointestinal_tract_polyps | 1.27619165 |
63 | MP0003656_abnormal_erythrocyte_physiolo | 1.27287319 |
64 | MP0003453_abnormal_keratinocyte_physiol | 1.25826341 |
65 | MP0002332_abnormal_exercise_endurance | 1.25756367 |
66 | MP0000343_altered_response_to | 1.20779841 |
67 | MP0003191_abnormal_cellular_cholesterol | 1.16103597 |
68 | MP0005164_abnormal_response_to | 1.11321969 |
69 | MP0003448_altered_tumor_morphology | 1.06723950 |
70 | MP0003690_abnormal_glial_cell | 1.04912904 |
71 | MP0008260_abnormal_autophagy | 1.03161742 |
72 | MP0004883_abnormal_blood_vessel | 1.03116848 |
73 | MP0002998_abnormal_bone_remodeling | 1.01662244 |
74 | MP0005174_abnormal_tail_pigmentation | 0.97347243 |
75 | MP0002132_abnormal_respiratory_system | 0.92801161 |
76 | MP0005167_abnormal_blood-brain_barrier | 0.92594874 |
77 | MP0010368_abnormal_lymphatic_system | 0.91544125 |
78 | MP0000609_abnormal_liver_physiology | 0.90314808 |
79 | MP0000604_amyloidosis | 0.88301735 |
80 | MP0009763_increased_sensitivity_to | 0.88185328 |
81 | MP0003183_abnormal_peptide_metabolism | 0.87295405 |
82 | MP0009840_abnormal_foam_cell | 0.86081449 |
83 | MP0008007_abnormal_cellular_replicative | 0.85563317 |
84 | MP0005076_abnormal_cell_differentiation | 0.85014886 |
85 | MP0005365_abnormal_bile_salt | 0.83916911 |
86 | MP0001216_abnormal_epidermal_layer | 0.83868961 |
87 | MP0004130_abnormal_muscle_cell | 0.81551023 |
88 | MP0003075_altered_response_to | 0.81079420 |
89 | MP0002928_abnormal_bile_duct | 0.79779458 |
90 | MP0005390_skeleton_phenotype | 0.78469079 |
91 | MP0000249_abnormal_blood_vessel | 0.77925290 |
92 | MP0003943_abnormal_hepatobiliary_system | 0.77323092 |
93 | MP0005058_abnormal_lysosome_morphology | 0.76043059 |
94 | MP0002060_abnormal_skin_morphology | 0.75122296 |
95 | MP0002019_abnormal_tumor_incidence | 0.74795828 |
96 | MP0010234_abnormal_vibrissa_follicle | 0.74746130 |
97 | MP0005023_abnormal_wound_healing | 0.74415234 |
98 | MP0005535_abnormal_body_temperature | 0.72768955 |
99 | MP0004782_abnormal_surfactant_physiolog | 0.72075175 |
100 | MP0001879_abnormal_lymphatic_vessel | 0.71891935 |
101 | MP0005075_abnormal_melanosome_morpholog | 0.71828003 |
102 | MP0003795_abnormal_bone_structure | 0.71673447 |
103 | MP0002136_abnormal_kidney_physiology | 0.71645513 |
104 | MP0002277_abnormal_respiratory_mucosa | 0.70827365 |
105 | MP0003091_abnormal_cell_migration | 0.70676404 |
106 | MP0002693_abnormal_pancreas_physiology | 0.69862508 |
107 | MP0003045_fibrosis | 0.69847750 |
108 | MP0001191_abnormal_skin_condition | 0.69711520 |
109 | MP0004381_abnormal_hair_follicle | 0.69276454 |
110 | MP0003195_calcinosis | 0.69192617 |
111 | MP0005166_decreased_susceptibility_to | 0.69136518 |
112 | MP0002139_abnormal_hepatobiliary_system | 0.67997075 |
113 | MP0006054_spinal_hemorrhage | 0.66737656 |
114 | MP0009765_abnormal_xenobiotic_induced | 0.64513259 |
115 | MP0008961_abnormal_basal_metabolism | 0.63810341 |
116 | MP0001501_abnormal_sleep_pattern | 0.63478496 |
117 | MP0008874_decreased_physiological_sensi | 0.62890469 |
118 | MP0001663_abnormal_digestive_system | 0.62159952 |
119 | MP0004484_altered_response_of | 0.61838713 |
120 | MP0005666_abnormal_adipose_tissue | 0.58760923 |
121 | MP0003646_muscle_fatigue | 0.55875837 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myositis (HP:0100614) | 4.93754946 |
2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.92931817 |
3 | Eczematoid dermatitis (HP:0000976) | 4.33264287 |
4 | Orchitis (HP:0100796) | 4.13635811 |
5 | Recurrent abscess formation (HP:0002722) | 4.07144239 |
6 | Chronic otitis media (HP:0000389) | 3.89179417 |
7 | Optic neuritis (HP:0100653) | 3.85037817 |
8 | Retrobulbar optic neuritis (HP:0100654) | 3.85037817 |
9 | Recurrent bacterial skin infections (HP:0005406) | 3.77805917 |
10 | IgM deficiency (HP:0002850) | 3.77315314 |
11 | Stomatitis (HP:0010280) | 3.75441990 |
12 | Recurrent fungal infections (HP:0002841) | 3.67163275 |
13 | Recurrent bronchitis (HP:0002837) | 3.58534122 |
14 | Nasal polyposis (HP:0100582) | 3.41058011 |
15 | Abnormality of the nasal mucosa (HP:0000433) | 3.32980695 |
16 | Interstitial pulmonary disease (HP:0006530) | 3.27940861 |
17 | T lymphocytopenia (HP:0005403) | 3.24003422 |
18 | Thrombocytosis (HP:0001894) | 3.21772380 |
19 | Recurrent viral infections (HP:0004429) | 3.20718870 |
20 | Inflammation of the large intestine (HP:0002037) | 3.20469236 |
21 | Abnormality of T cell number (HP:0011839) | 3.20096701 |
22 | Colitis (HP:0002583) | 3.19901997 |
23 | Arterial thrombosis (HP:0004420) | 3.17852284 |
24 | Abnormality of T cells (HP:0002843) | 3.17399129 |
25 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.12417055 |
26 | Gastrointestinal inflammation (HP:0004386) | 3.08858909 |
27 | Pustule (HP:0200039) | 3.07431705 |
28 | Recurrent skin infections (HP:0001581) | 3.06825546 |
29 | Vasculitis (HP:0002633) | 3.00601373 |
30 | Recurrent cutaneous fungal infections (HP:0011370) | 3.00063465 |
31 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.00063465 |
32 | Spontaneous hematomas (HP:0007420) | 2.97893664 |
33 | Abnormality of T cell physiology (HP:0011840) | 2.95793754 |
34 | Mediastinal lymphadenopathy (HP:0100721) | 2.93981668 |
35 | Abnormality of glycolipid metabolism (HP:0010969) | 2.89951208 |
36 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.89951208 |
37 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.89951208 |
38 | Meningitis (HP:0001287) | 2.88527928 |
39 | Increased IgE level (HP:0003212) | 2.84898651 |
40 | Hematochezia (HP:0002573) | 2.82516546 |
41 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.79354873 |
42 | Gingival bleeding (HP:0000225) | 2.79086563 |
43 | Autoimmune thrombocytopenia (HP:0001973) | 2.75272651 |
44 | Abnormality of the fingertips (HP:0001211) | 2.73731403 |
45 | Epistaxis (HP:0000421) | 2.73627970 |
46 | Chronic diarrhea (HP:0002028) | 2.73181830 |
47 | Hemoptysis (HP:0002105) | 2.72713905 |
48 | Episodic fever (HP:0001954) | 2.69190368 |
49 | Panhypogammaglobulinemia (HP:0003139) | 2.68418926 |
50 | Systemic lupus erythematosus (HP:0002725) | 2.67932702 |
51 | Pulmonary infiltrates (HP:0002113) | 2.67155103 |
52 | Abnormality of macrophages (HP:0004311) | 2.65538009 |
53 | Keratoconjunctivitis sicca (HP:0001097) | 2.63729364 |
54 | Amyloidosis (HP:0011034) | 2.57267430 |
55 | Thyroiditis (HP:0100646) | 2.55719030 |
56 | Dysostosis multiplex (HP:0000943) | 2.52506117 |
57 | Keratoconjunctivitis (HP:0001096) | 2.51256995 |
58 | Prolonged bleeding time (HP:0003010) | 2.48465489 |
59 | Agammaglobulinemia (HP:0004432) | 2.48429057 |
60 | Autoimmune hemolytic anemia (HP:0001890) | 2.48051467 |
61 | Cellulitis (HP:0100658) | 2.47884657 |
62 | Increased serum ferritin (HP:0003281) | 2.47041400 |
63 | Lymphopenia (HP:0001888) | 2.46963420 |
64 | Abnormality of the pleura (HP:0002103) | 2.45034468 |
65 | Gastrointestinal infarctions (HP:0005244) | 2.43241124 |
66 | Leukocytosis (HP:0001974) | 2.42039206 |
67 | Impaired platelet aggregation (HP:0003540) | 2.38490648 |
68 | Abnormal platelet function (HP:0011869) | 2.38490648 |
69 | Gastrointestinal stroma tumor (HP:0100723) | 2.34778269 |
70 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.34372670 |
71 | IgG deficiency (HP:0004315) | 2.31330133 |
72 | Fatigue (HP:0012378) | 2.31040609 |
73 | Gingivitis (HP:0000230) | 2.30597320 |
74 | Abnormality of iron homeostasis (HP:0011031) | 2.30530681 |
75 | Pulmonary embolism (HP:0002204) | 2.30059824 |
76 | Abnormality of eosinophils (HP:0001879) | 2.29252614 |
77 | Vacuolated lymphocytes (HP:0001922) | 2.27374229 |
78 | Periodontitis (HP:0000704) | 2.27046810 |
79 | Petechiae (HP:0000967) | 2.26782389 |
80 | Encephalitis (HP:0002383) | 2.25252618 |
81 | Severe combined immunodeficiency (HP:0004430) | 2.24819253 |
82 | Bronchitis (HP:0012387) | 2.24522532 |
83 | Chest pain (HP:0100749) | 2.23989604 |
84 | Myocardial infarction (HP:0001658) | 2.22580743 |
85 | Sepsis (HP:0100806) | 2.21612314 |
86 | Abnormality of B cell number (HP:0010975) | 2.20994179 |
87 | B lymphocytopenia (HP:0010976) | 2.20994179 |
88 | Spondylolisthesis (HP:0003302) | 2.20572307 |
89 | Emphysema (HP:0002097) | 2.20546931 |
90 | Joint swelling (HP:0001386) | 2.20254267 |
91 | Alveolar cell carcinoma (HP:0006519) | 2.14884758 |
92 | Hypergammaglobulinemia (HP:0010702) | 2.14507328 |
93 | Vertigo (HP:0002321) | 2.12059051 |
94 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.11644626 |
95 | Acute myeloid leukemia (HP:0004808) | 2.11241262 |
96 | Polycythemia (HP:0001901) | 2.10838071 |
97 | Increased cerebral lipofuscin (HP:0011813) | 2.10758296 |
98 | Purpura (HP:0000979) | 2.08672663 |
99 | Combined immunodeficiency (HP:0005387) | 2.07438109 |
100 | Chronic obstructive pulmonary disease (HP:0006510) | 2.07049557 |
101 | Obstructive lung disease (HP:0006536) | 2.07049557 |
102 | Recurrent pneumonia (HP:0006532) | 2.07041848 |
103 | Thrombophlebitis (HP:0004418) | 2.06671243 |
104 | Abnormality of the peritoneum (HP:0002585) | 2.06325118 |
105 | Eosinophilia (HP:0001880) | 2.05288848 |
106 | Abnormality of the prostate (HP:0008775) | 2.04961823 |
107 | Abnormality of the endocardium (HP:0004306) | 2.04618519 |
108 | Acne (HP:0001061) | 2.03885502 |
109 | Loss of speech (HP:0002371) | 2.03682631 |
110 | Hypochromic anemia (HP:0001931) | 2.00079238 |
111 | Restrictive lung disease (HP:0002091) | 1.99000384 |
112 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.97555170 |
113 | Arthralgia (HP:0002829) | 1.97478584 |
114 | Depressed nasal tip (HP:0000437) | 1.96633097 |
115 | Recurrent sinusitis (HP:0011108) | 1.96418503 |
116 | Slow saccadic eye movements (HP:0000514) | 1.95837841 |
117 | Microcytic anemia (HP:0001935) | 1.95652427 |
118 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.94215304 |
119 | Stomach cancer (HP:0012126) | 1.93452271 |
120 | Urticaria (HP:0001025) | 1.92527381 |
121 | Hypoplasia of the thymus (HP:0000778) | 1.92175485 |
122 | Granulocytopenia (HP:0001913) | 1.91706945 |
123 | Polyneuropathy (HP:0001271) | 1.91241254 |
124 | Increased IgM level (HP:0003496) | 1.86843648 |
125 | Gangrene (HP:0100758) | 1.83761773 |
126 | Anorexia (HP:0002039) | 1.83703554 |
127 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.83025233 |
128 | Osteomyelitis (HP:0002754) | 1.81812149 |
129 | Esophageal varix (HP:0002040) | 1.80428410 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 3.40070348 |
2 | TYK2 | 2.83821587 |
3 | MAP3K14 | 2.80113084 |
4 | IKBKE | 2.70040971 |
5 | JAK3 | 2.67960656 |
6 | TBK1 | 2.67057776 |
7 | MAPK15 | 2.56061333 |
8 | TXK | 2.55927485 |
9 | TGFBR2 | 2.29488330 |
10 | NLK | 2.24538084 |
11 | PRPF4B | 2.17412634 |
12 | TEC | 2.10584035 |
13 | IKBKB | 2.06206421 |
14 | FLT3 | 2.04745745 |
15 | FGFR4 | 2.02661992 |
16 | ERN1 | 2.01925711 |
17 | KIT | 1.98784154 |
18 | STK10 | 1.88960041 |
19 | ITK | 1.88458795 |
20 | ZAP70 | 1.85460574 |
21 | JAK1 | 1.79286710 |
22 | CHUK | 1.72836190 |
23 | TAOK3 | 1.72671134 |
24 | FES | 1.72548066 |
25 | BTK | 1.65733635 |
26 | IRAK4 | 1.65393122 |
27 | MAP3K13 | 1.63210886 |
28 | IRAK3 | 1.59121237 |
29 | EPHA3 | 1.56484322 |
30 | EPHB1 | 1.53449753 |
31 | BMPR2 | 1.49708691 |
32 | TAOK1 | 1.49134102 |
33 | MAP3K10 | 1.48991764 |
34 | TAOK2 | 1.48714827 |
35 | TNK2 | 1.41255600 |
36 | RPS6KA4 | 1.34799683 |
37 | NME2 | 1.34171776 |
38 | CSK | 1.31789553 |
39 | PIM1 | 1.29910381 |
40 | CSF1R | 1.28578474 |
41 | MAPKAPK3 | 1.27263005 |
42 | FGFR3 | 1.26300834 |
43 | MST4 | 1.23111016 |
44 | LCK | 1.19787126 |
45 | MAP2K3 | 1.15975092 |
46 | HIPK2 | 1.10755254 |
47 | FGR | 1.09350824 |
48 | BLK | 1.09173583 |
49 | JAK2 | 1.09081628 |
50 | IRAK2 | 1.07547108 |
51 | IRAK1 | 1.05190086 |
52 | KDR | 1.03743790 |
53 | EEF2K | 1.01436555 |
54 | LRRK2 | 0.98636722 |
55 | PTK6 | 0.98222709 |
56 | PIM2 | 0.98029261 |
57 | HCK | 0.96380536 |
58 | SYK | 0.96314622 |
59 | CDK9 | 0.95273210 |
60 | TGFBR1 | 0.94915640 |
61 | GRK6 | 0.93225731 |
62 | DYRK3 | 0.91442962 |
63 | ACVR1B | 0.88971495 |
64 | PIK3CG | 0.84001584 |
65 | MARK2 | 0.83957274 |
66 | MAPK7 | 0.83580282 |
67 | MAP3K3 | 0.82605662 |
68 | MATK | 0.80500643 |
69 | MARK3 | 0.79038041 |
70 | CDC42BPA | 0.76688628 |
71 | MAP2K2 | 0.75931677 |
72 | MAPK12 | 0.74473531 |
73 | MOS | 0.74152209 |
74 | RPS6KB2 | 0.72388027 |
75 | SGK2 | 0.70370354 |
76 | RPS6KA5 | 0.69709528 |
77 | RIPK1 | 0.69634582 |
78 | PDK1 | 0.68903899 |
79 | CLK1 | 0.68371420 |
80 | RPS6KL1 | 0.66930023 |
81 | RPS6KC1 | 0.66930023 |
82 | SIK3 | 0.65808899 |
83 | MAPKAPK5 | 0.64288094 |
84 | DYRK1B | 0.63822298 |
85 | SGK3 | 0.63585056 |
86 | LYN | 0.63204103 |
87 | MAP3K5 | 0.63053773 |
88 | FRK | 0.61722168 |
89 | MAPK11 | 0.61571857 |
90 | TIE1 | 0.60322407 |
91 | RIPK4 | 0.59834535 |
92 | MAP3K12 | 0.58000483 |
93 | MAP3K1 | 0.57255989 |
94 | PKN2 | 0.56257725 |
95 | TRIB3 | 0.54424235 |
96 | MAP3K7 | 0.54282008 |
97 | SIK1 | 0.52928937 |
98 | TRPM7 | 0.50908432 |
99 | PRKCQ | 0.50438983 |
100 | STK4 | 0.50335143 |
101 | MAPKAPK2 | 0.50091644 |
102 | CDK6 | 0.48744107 |
103 | PRKAA2 | 0.48297492 |
104 | BMPR1B | 0.47586185 |
105 | FYN | 0.46521612 |
106 | PDPK1 | 0.43188540 |
107 | VRK1 | 0.40944467 |
108 | RPS6KA6 | 0.40246851 |
109 | KSR2 | 0.40101769 |
110 | YES1 | 0.39619189 |
111 | DMPK | 0.39057749 |
112 | CDK12 | 0.39014660 |
113 | NEK9 | 0.37984733 |
114 | ABL1 | 0.37961051 |
115 | MAP3K6 | 0.37716554 |
116 | AKT3 | 0.37358869 |
117 | MAP3K11 | 0.36990210 |
118 | MAP2K6 | 0.36684515 |
119 | MAPK4 | 0.36490646 |
120 | PRKG2 | 0.35325224 |
121 | PRKD2 | 0.35108139 |
122 | CAMKK2 | 0.34717433 |
123 | INSRR | 0.33356550 |
124 | OBSCN | 0.32807914 |
125 | SGK494 | 0.32805983 |
126 | SGK223 | 0.32805983 |
127 | MUSK | 0.32584136 |
128 | DDR2 | 0.32445824 |
129 | MAPK3 | 0.32040472 |
130 | STK11 | 0.31566884 |
131 | MELK | 0.31529341 |
132 | STK38 | 0.31391118 |
133 | GRK7 | 0.30365819 |
134 | IGF1R | 0.30252203 |
135 | CDK8 | 0.29861950 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.00342128 |
2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.00077894 |
3 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.82995001 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.81394422 |
5 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.52063648 |
6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.36760982 |
7 | Measles_Homo sapiens_hsa05162 | 2.36605755 |
8 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.08733185 |
9 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.03817235 |
10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.02788688 |
11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.01918647 |
12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.00160538 |
13 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.97549544 |
14 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.89863822 |
15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.88655195 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.88532359 |
17 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.88240226 |
18 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.81905354 |
19 | Legionellosis_Homo sapiens_hsa05134 | 1.81073465 |
20 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.78241951 |
21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.77709191 |
22 | Allograft rejection_Homo sapiens_hsa05330 | 1.70663969 |
23 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.61941950 |
24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.58572429 |
25 | Influenza A_Homo sapiens_hsa05164 | 1.54100334 |
26 | Malaria_Homo sapiens_hsa05144 | 1.53346049 |
27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.46041386 |
28 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.45130279 |
29 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.41239374 |
30 | Pertussis_Homo sapiens_hsa05133 | 1.40845180 |
31 | Hepatitis B_Homo sapiens_hsa05161 | 1.39561114 |
32 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.34032694 |
33 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.33110229 |
34 | Apoptosis_Homo sapiens_hsa04210 | 1.27825872 |
35 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.25267538 |
36 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.17069843 |
37 | Shigellosis_Homo sapiens_hsa05131 | 1.16825104 |
38 | Tuberculosis_Homo sapiens_hsa05152 | 1.14471826 |
39 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.12978321 |
40 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.10179086 |
41 | Other glycan degradation_Homo sapiens_hsa00511 | 1.08529531 |
42 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.07447354 |
43 | Hepatitis C_Homo sapiens_hsa05160 | 1.06876793 |
44 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.05241411 |
45 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.04137578 |
46 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03647337 |
47 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.94412419 |
48 | Salmonella infection_Homo sapiens_hsa05132 | 0.93848065 |
49 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.92568225 |
50 | Asthma_Homo sapiens_hsa05310 | 0.91997204 |
51 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.90064703 |
52 | Platelet activation_Homo sapiens_hsa04611 | 0.87450383 |
53 | Viral myocarditis_Homo sapiens_hsa05416 | 0.86269943 |
54 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.84276922 |
55 | Insulin resistance_Homo sapiens_hsa04931 | 0.81667937 |
56 | Phagosome_Homo sapiens_hsa04145 | 0.79491652 |
57 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.78905682 |
58 | Ribosome_Homo sapiens_hsa03010 | 0.77478392 |
59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.73979044 |
60 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73218684 |
61 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.73131711 |
62 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.72539012 |
63 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.72079695 |
64 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.70748393 |
65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.68586174 |
66 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.67153776 |
67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66899675 |
68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66882504 |
69 | ABC transporters_Homo sapiens_hsa02010 | 0.66427323 |
70 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.66017500 |
71 | Thyroid cancer_Homo sapiens_hsa05216 | 0.65654794 |
72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.64316165 |
73 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.63381231 |
74 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.61755988 |
75 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.61349638 |
76 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58146982 |
77 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57591765 |
78 | Colorectal cancer_Homo sapiens_hsa05210 | 0.57560035 |
79 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.57402918 |
80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.57278291 |
81 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.56201887 |
82 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.55873749 |
83 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.51556192 |
84 | Amoebiasis_Homo sapiens_hsa05146 | 0.50485492 |
85 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.50343525 |
86 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.50157195 |
87 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.49198967 |
88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48630225 |
89 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47549743 |
90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.47500430 |
91 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.46807141 |
92 | Prostate cancer_Homo sapiens_hsa05215 | 0.46303469 |
93 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46245411 |
94 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.46149360 |
95 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.45252451 |
96 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.45238105 |
97 | Lysosome_Homo sapiens_hsa04142 | 0.44620805 |
98 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.43118449 |
99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.43045312 |
100 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.42428785 |
101 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.40938639 |
102 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.38776692 |
103 | Prion diseases_Homo sapiens_hsa05020 | 0.38465109 |
104 | Protein export_Homo sapiens_hsa03060 | 0.37877506 |
105 | Pathways in cancer_Homo sapiens_hsa05200 | 0.37792273 |
106 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.36798555 |
107 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36750543 |
108 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36595875 |
109 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35702509 |
110 | Adherens junction_Homo sapiens_hsa04520 | 0.34668564 |
111 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34286604 |
112 | Endocytosis_Homo sapiens_hsa04144 | 0.33885687 |
113 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.33218086 |
114 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33103540 |
115 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32907422 |
116 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.32329418 |
117 | Endometrial cancer_Homo sapiens_hsa05213 | 0.31865856 |
118 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.30729393 |
119 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.29907201 |
120 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.29450175 |
121 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.28610561 |
122 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28461929 |
123 | Sulfur relay system_Homo sapiens_hsa04122 | 0.28307629 |
124 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.26607066 |
125 | Histidine metabolism_Homo sapiens_hsa00340 | 0.23568694 |
126 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.22703290 |
127 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.22617276 |
128 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.21942108 |