Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 9.28173407 |
2 | Golgi transport vesicle coating (GO:0048200) | 9.28173407 |
3 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 6.86563427 |
4 | protein retention in ER lumen (GO:0006621) | 6.29659718 |
5 | COPII vesicle coating (GO:0048208) | 5.38197824 |
6 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 5.12294099 |
7 | protein maturation by protein folding (GO:0022417) | 5.07142900 |
8 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 5.04117524 |
9 | positive regulation of nuclease activity (GO:0032075) | 4.90929992 |
10 | collagen fibril organization (GO:0030199) | 4.45860986 |
11 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 4.45329672 |
12 | regulation of nuclease activity (GO:0032069) | 4.43372905 |
13 | exocrine pancreas development (GO:0031017) | 4.35999380 |
14 | endoplasmic reticulum unfolded protein response (GO:0030968) | 4.32079872 |
15 | cellular response to vitamin D (GO:0071305) | 4.27873054 |
16 | cellular response to unfolded protein (GO:0034620) | 4.21591527 |
17 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 4.12751693 |
18 | cellular response to topologically incorrect protein (GO:0035967) | 4.11006604 |
19 | protein heterotrimerization (GO:0070208) | 4.09374278 |
20 | vesicle coating (GO:0006901) | 4.06289599 |
21 | keratan sulfate catabolic process (GO:0042340) | 4.04328121 |
22 | type B pancreatic cell development (GO:0003323) | 3.96934347 |
23 | glandular epithelial cell development (GO:0002068) | 3.96730640 |
24 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.96071970 |
25 | ER-nucleus signaling pathway (GO:0006984) | 3.91877392 |
26 | sequestering of metal ion (GO:0051238) | 3.90608483 |
27 | cellular response to vitamin (GO:0071295) | 3.79534628 |
28 | peptidyl-proline hydroxylation (GO:0019511) | 3.75765516 |
29 | endocrine pancreas development (GO:0031018) | 3.72911191 |
30 | skin morphogenesis (GO:0043589) | 3.70376181 |
31 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 3.69134724 |
32 | signal peptide processing (GO:0006465) | 3.56952267 |
33 | peptide hormone processing (GO:0016486) | 3.56898186 |
34 | adherens junction assembly (GO:0034333) | 3.49821326 |
35 | response to unfolded protein (GO:0006986) | 3.48076469 |
36 | protein hydroxylation (GO:0018126) | 3.44262327 |
37 | protein localization to endosome (GO:0036010) | 3.42631225 |
38 | cell-substrate junction assembly (GO:0007044) | 3.41539346 |
39 | response to endoplasmic reticulum stress (GO:0034976) | 3.41113927 |
40 | response to topologically incorrect protein (GO:0035966) | 3.38525253 |
41 | negative regulation of fatty acid transport (GO:2000192) | 3.33076793 |
42 | endodermal cell differentiation (GO:0035987) | 3.32026694 |
43 | cell-substrate adherens junction assembly (GO:0007045) | 3.31529901 |
44 | focal adhesion assembly (GO:0048041) | 3.31529901 |
45 | mannose metabolic process (GO:0006013) | 3.28687760 |
46 | 4-hydroxyproline metabolic process (GO:0019471) | 3.27758794 |
47 | cellular response to nutrient (GO:0031670) | 3.24550867 |
48 | regulation of extracellular matrix disassembly (GO:0010715) | 3.23877038 |
49 | apoptotic cell clearance (GO:0043277) | 3.23203439 |
50 | substrate-dependent cell migration (GO:0006929) | 3.21758210 |
51 | semaphorin-plexin signaling pathway (GO:0071526) | 3.20968870 |
52 | chondrocyte proliferation (GO:0035988) | 3.17668389 |
53 | basement membrane organization (GO:0071711) | 3.16732549 |
54 | regulation of early endosome to late endosome transport (GO:2000641) | 3.14170720 |
55 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 3.12662363 |
56 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 3.12360846 |
57 | positive regulation of extracellular matrix organization (GO:1903055) | 3.11119289 |
58 | glandular epithelial cell differentiation (GO:0002067) | 3.08542039 |
59 | bone trabecula formation (GO:0060346) | 3.07998725 |
60 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 3.07903208 |
61 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.07486965 |
62 | kidney mesenchyme development (GO:0072074) | 3.04945055 |
63 | polarized epithelial cell differentiation (GO:0030859) | 3.01797475 |
64 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.99817715 |
65 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.99337918 |
66 | peptidyl-asparagine modification (GO:0018196) | 2.98852935 |
67 | regulation of establishment of planar polarity (GO:0090175) | 2.98600433 |
68 | cell migration involved in heart development (GO:0060973) | 2.94798221 |
69 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.94131215 |
70 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.93327657 |
71 | atrioventricular valve morphogenesis (GO:0003181) | 2.93032724 |
72 | collagen metabolic process (GO:0032963) | 2.91500722 |
73 | epithelial cell-cell adhesion (GO:0090136) | 2.91285430 |
74 | establishment of apical/basal cell polarity (GO:0035089) | 2.90602972 |
75 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.88547408 |
76 | endothelial cell morphogenesis (GO:0001886) | 2.87496632 |
77 | extracellular matrix assembly (GO:0085029) | 2.86915428 |
78 | barbed-end actin filament capping (GO:0051016) | 2.85723855 |
79 | columnar/cuboidal epithelial cell development (GO:0002066) | 2.85243672 |
80 | hypotonic response (GO:0006971) | 2.84220052 |
81 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.84050578 |
82 | collagen catabolic process (GO:0030574) | 2.83619749 |
83 | wound healing, spreading of epidermal cells (GO:0035313) | 2.81387497 |
84 | convergent extension (GO:0060026) | 2.80706726 |
85 | wound healing, spreading of cells (GO:0044319) | 2.79057906 |
86 | mesodermal cell differentiation (GO:0048333) | 2.77855841 |
87 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 2.77542633 |
88 | response to laminar fluid shear stress (GO:0034616) | 2.76734498 |
89 | negative regulation of cartilage development (GO:0061037) | 2.73817350 |
90 | positive regulation of hormone biosynthetic process (GO:0046886) | 2.73594344 |
91 | type B pancreatic cell proliferation (GO:0044342) | 2.73009863 |
92 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.72751771 |
93 | positive regulation of osteoblast proliferation (GO:0033690) | 2.72523803 |
94 | venous blood vessel morphogenesis (GO:0048845) | 2.72320539 |
95 | protein N-linked glycosylation (GO:0006487) | 2.71220637 |
96 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.71217844 |
97 | cochlea morphogenesis (GO:0090103) | 2.70763948 |
98 | epithelial cell fate commitment (GO:0072148) | 2.70416093 |
99 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.66921772 |
100 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.66348796 |
101 | fibril organization (GO:0097435) | 2.65182620 |
102 | extracellular matrix disassembly (GO:0022617) | 2.64289963 |
103 | multicellular organismal catabolic process (GO:0044243) | 2.64247077 |
104 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.63022079 |
105 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.62823027 |
106 | maintenance of protein localization in organelle (GO:0072595) | 2.62690042 |
107 | endothelial cell chemotaxis (GO:0035767) | 2.62475828 |
108 | embryo implantation (GO:0007566) | 2.61629571 |
109 | multicellular organismal metabolic process (GO:0044236) | 2.61083365 |
110 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.61057691 |
111 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.60889737 |
112 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.60707557 |
113 | hemidesmosome assembly (GO:0031581) | 2.60533224 |
114 | chondroitin sulfate biosynthetic process (GO:0030206) | 2.59844622 |
115 | toxin metabolic process (GO:0009404) | 2.59757966 |
116 | nitric oxide mediated signal transduction (GO:0007263) | 2.58302369 |
117 | gland morphogenesis (GO:0022612) | 2.58038697 |
118 | positive regulation of receptor recycling (GO:0001921) | 2.57965622 |
119 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.57814248 |
120 | metanephric mesenchyme development (GO:0072075) | 2.56522058 |
121 | endocardial cushion development (GO:0003197) | 2.56433671 |
122 | extracellular fibril organization (GO:0043206) | 2.56237797 |
123 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.55840190 |
124 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.55155142 |
125 | adhesion of symbiont to host (GO:0044406) | 2.54120608 |
126 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.53490840 |
127 | regulation of plasminogen activation (GO:0010755) | 2.53192399 |
128 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.52799113 |
129 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.51495893 |
130 | positive regulation of p38MAPK cascade (GO:1900745) | 2.50674505 |
131 | paraxial mesoderm development (GO:0048339) | 2.50643202 |
132 | stress fiber assembly (GO:0043149) | 2.50069820 |
133 | regulation of extracellular matrix organization (GO:1903053) | 2.49479800 |
134 | maternal placenta development (GO:0001893) | 2.46761498 |
135 | cardiac myofibril assembly (GO:0055003) | 2.46718052 |
136 | membrane protein ectodomain proteolysis (GO:0006509) | 2.46360823 |
137 | blood vessel endothelial cell migration (GO:0043534) | 2.45672563 |
138 | hyaluronan catabolic process (GO:0030214) | 2.44709098 |
139 | extracellular matrix organization (GO:0030198) | 2.44113240 |
140 | Golgi organization (GO:0007030) | 2.43944667 |
141 | tooth mineralization (GO:0034505) | 2.43735173 |
142 | chondrocyte development (GO:0002063) | 2.42944480 |
143 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.39576211 |
144 | astrocyte differentiation (GO:0048708) | 2.38824959 |
145 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 2.38205480 |
146 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.37664838 |
147 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.37542715 |
148 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.35327169 |
149 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.33873283 |
150 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.33445511 |
151 | decidualization (GO:0046697) | 2.33435502 |
152 | cell adhesion mediated by integrin (GO:0033627) | 2.33254396 |
153 | positive regulation of insulin secretion (GO:0032024) | 2.33184320 |
154 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.33144104 |
155 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.33107727 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.23493623 |
2 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.75817923 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.43447244 |
4 | CLOCK_20551151_ChIP-Seq_293T_Human | 3.12391910 |
5 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.93132540 |
6 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.83710885 |
7 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.81968954 |
8 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.80220689 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.52445809 |
10 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.37222206 |
11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.36700593 |
12 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.14185177 |
13 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.13238937 |
14 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.06110689 |
15 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.00446273 |
16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99201858 |
17 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.93063811 |
18 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.92305729 |
19 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.86135326 |
20 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.84320926 |
21 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.83746557 |
22 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.82896382 |
23 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.79145035 |
24 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.76717549 |
25 | ATF3_27146783_Chip-Seq_COLON_Human | 1.76155870 |
26 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.70183587 |
27 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.69441738 |
28 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.69309884 |
29 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.65996475 |
30 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.64868168 |
31 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.64596306 |
32 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.63906948 |
33 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.63067449 |
34 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.61940711 |
35 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.61870613 |
36 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.57980546 |
37 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.56035329 |
38 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.55276848 |
39 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.55276848 |
40 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.55023950 |
41 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.54818755 |
42 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.52231024 |
43 | MYC_22102868_ChIP-Seq_BL_Human | 1.51092291 |
44 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.50448851 |
45 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.48382596 |
46 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.48362721 |
47 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.47947021 |
48 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.47675386 |
49 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.46223081 |
50 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.44719526 |
51 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.41913671 |
52 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.40429785 |
53 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.39953911 |
54 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.39949563 |
55 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.39394636 |
56 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.35809545 |
57 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.34280892 |
58 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.32851614 |
59 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.31518476 |
60 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.31105390 |
61 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.29593322 |
62 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.28479910 |
63 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.26549905 |
64 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.25947821 |
65 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.24931664 |
66 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.23961442 |
67 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.23835005 |
68 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.22984432 |
69 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.22336379 |
70 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.20788497 |
71 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.20749931 |
72 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.20622619 |
73 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.20263976 |
74 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.19673797 |
75 | CJUN_26792858_Chip-Seq_BT549_Human | 1.19473547 |
76 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.18623704 |
77 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.18225626 |
78 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.16956698 |
79 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.16432298 |
80 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.14979555 |
81 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.13131941 |
82 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.13117152 |
83 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.12767198 |
84 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.12555604 |
85 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10860066 |
86 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.10329581 |
87 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.09766340 |
88 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.09195793 |
89 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 1.08847444 |
90 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.07759493 |
91 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.07220178 |
92 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.06357961 |
93 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.06059893 |
94 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.05595386 |
95 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.05528603 |
96 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.04478163 |
97 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.04034146 |
98 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.03191370 |
99 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.03130101 |
100 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.03107302 |
101 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.02721724 |
102 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.02649067 |
103 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.02522900 |
104 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.02303531 |
105 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.01746998 |
106 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.01152076 |
107 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.00396595 |
108 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.00337149 |
109 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.98997644 |
110 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97713594 |
111 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.97526131 |
112 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.97202358 |
113 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.96676041 |
114 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96052946 |
115 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.95988409 |
116 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.93848917 |
117 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.93691744 |
118 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.93678784 |
119 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.93636019 |
120 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.93561529 |
121 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.93033744 |
122 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.92643957 |
123 | * P68_20966046_ChIP-Seq_HELA_Human | 0.92539370 |
124 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.91532962 |
125 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.91254079 |
126 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.91193894 |
127 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91120225 |
128 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.89866811 |
129 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.89671324 |
130 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.89331558 |
131 | * KDM2B_26808549_Chip-Seq_K562_Human | 0.89021999 |
132 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.88358445 |
133 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.87273768 |
134 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.87273768 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 5.55770941 |
2 | MP0002877_abnormal_melanocyte_morpholog | 3.62986898 |
3 | MP0003283_abnormal_digestive_organ | 3.40928511 |
4 | MP0005503_abnormal_tendon_morphology | 3.32568572 |
5 | MP0003705_abnormal_hypodermis_morpholog | 3.06201466 |
6 | MP0005275_abnormal_skin_tensile | 3.04746000 |
7 | MP0003279_aneurysm | 2.82188248 |
8 | MP0000013_abnormal_adipose_tissue | 2.78112796 |
9 | MP0004272_abnormal_basement_membrane | 2.55987145 |
10 | MP0005257_abnormal_intraocular_pressure | 2.47825171 |
11 | MP0006054_spinal_hemorrhage | 2.34914650 |
12 | MP0000678_abnormal_parathyroid_gland | 2.05420784 |
13 | MP0003566_abnormal_cell_adhesion | 2.02730945 |
14 | MP0002896_abnormal_bone_mineralization | 1.89351935 |
15 | MP0002837_dystrophic_cardiac_calcinosis | 1.88483576 |
16 | MP0005508_abnormal_skeleton_morphology | 1.86473563 |
17 | MP0000003_abnormal_adipose_tissue | 1.84772706 |
18 | MP0003122_maternal_imprinting | 1.80472646 |
19 | MP0001944_abnormal_pancreas_morphology | 1.79302746 |
20 | MP0005220_abnormal_exocrine_pancreas | 1.75071312 |
21 | MP0009384_cardiac_valve_regurgitation | 1.71998605 |
22 | MP0009840_abnormal_foam_cell | 1.67078508 |
23 | MP0010368_abnormal_lymphatic_system | 1.59688222 |
24 | MP0001958_emphysema | 1.58818113 |
25 | MP0002693_abnormal_pancreas_physiology | 1.54551400 |
26 | MP0010030_abnormal_orbit_morphology | 1.53240747 |
27 | MP0009780_abnormal_chondrocyte_physiolo | 1.52902238 |
28 | MP0003123_paternal_imprinting | 1.50645711 |
29 | MP0005623_abnormal_meninges_morphology | 1.49328469 |
30 | MP0005023_abnormal_wound_healing | 1.47241351 |
31 | MP0002909_abnormal_adrenal_gland | 1.46275211 |
32 | MP0003300_gastrointestinal_ulcer | 1.41650963 |
33 | MP0004084_abnormal_cardiac_muscle | 1.40258589 |
34 | MP0010352_gastrointestinal_tract_polyps | 1.38060441 |
35 | MP0005409_darkened_coat_color | 1.36125752 |
36 | MP0005451_abnormal_body_composition | 1.33293567 |
37 | MP0000163_abnormal_cartilage_morphology | 1.30816519 |
38 | MP0001348_abnormal_lacrimal_gland | 1.30532656 |
39 | MP0002295_abnormal_pulmonary_circulatio | 1.28960622 |
40 | MP0003942_abnormal_urinary_system | 1.25645178 |
41 | MP0000428_abnormal_craniofacial_morphol | 1.24167583 |
42 | MP0003950_abnormal_plasma_membrane | 1.21979995 |
43 | MP0001915_intracranial_hemorrhage | 1.21815455 |
44 | MP0001270_distended_abdomen | 1.21758921 |
45 | MP0005076_abnormal_cell_differentiation | 1.21606804 |
46 | MP0001542_abnormal_bone_strength | 1.21479430 |
47 | MP0010386_abnormal_urinary_bladder | 1.20429942 |
48 | MP0002060_abnormal_skin_morphology | 1.19700637 |
49 | MP0002249_abnormal_larynx_morphology | 1.18536208 |
50 | MP0003091_abnormal_cell_migration | 1.17996289 |
51 | MP0002933_joint_inflammation | 1.16972732 |
52 | MP0000750_abnormal_muscle_regeneration | 1.14977803 |
53 | MP0000858_altered_metastatic_potential | 1.14588870 |
54 | MP0005390_skeleton_phenotype | 1.13416171 |
55 | MP0003195_calcinosis | 1.12870100 |
56 | MP0000767_abnormal_smooth_muscle | 1.09894057 |
57 | MP0009053_abnormal_anal_canal | 1.07119061 |
58 | MP0002234_abnormal_pharynx_morphology | 1.06308099 |
59 | MP0002254_reproductive_system_inflammat | 1.05849049 |
60 | MP0003795_abnormal_bone_structure | 1.05403241 |
61 | MP0004233_abnormal_muscle_weight | 1.05319330 |
62 | MP0004043_abnormal_pH_regulation | 1.04010063 |
63 | MP0000537_abnormal_urethra_morphology | 1.03964440 |
64 | MP0002115_abnormal_skeleton_extremities | 1.03963593 |
65 | MP0002108_abnormal_muscle_morphology | 1.03561238 |
66 | MP0000749_muscle_degeneration | 1.03067793 |
67 | MP0009250_abnormal_appendicular_skeleto | 1.02185863 |
68 | MP0003191_abnormal_cellular_cholesterol | 1.01551401 |
69 | MP0000462_abnormal_digestive_system | 1.00640163 |
70 | MP0008260_abnormal_autophagy | 1.00512363 |
71 | MP0003385_abnormal_body_wall | 0.98869477 |
72 | MP0001299_abnormal_eye_distance/ | 0.98700062 |
73 | MP0001614_abnormal_blood_vessel | 0.97671851 |
74 | MP0001243_abnormal_dermal_layer | 0.97458754 |
75 | MP0005058_abnormal_lysosome_morphology | 0.96716076 |
76 | MP0002113_abnormal_skeleton_development | 0.96669174 |
77 | MP0000534_abnormal_ureter_morphology | 0.94506945 |
78 | MP0005375_adipose_tissue_phenotype | 0.93157231 |
79 | MP0003119_abnormal_digestive_system | 0.93014298 |
80 | MP0002928_abnormal_bile_duct | 0.92694975 |
81 | MP0000733_abnormal_muscle_development | 0.91720074 |
82 | MP0003453_abnormal_keratinocyte_physiol | 0.88618601 |
83 | MP0002932_abnormal_joint_morphology | 0.87067016 |
84 | MP0001849_ear_inflammation | 0.87062419 |
85 | MP0002269_muscular_atrophy | 0.87020579 |
86 | MP0000049_abnormal_middle_ear | 0.86333238 |
87 | MP0000762_abnormal_tongue_morphology | 0.86218190 |
88 | MP0004185_abnormal_adipocyte_glucose | 0.86079307 |
89 | MP0001879_abnormal_lymphatic_vessel | 0.85943974 |
90 | MP0005164_abnormal_response_to | 0.85647152 |
91 | MP0000432_abnormal_head_morphology | 0.85279395 |
92 | MP0003935_abnormal_craniofacial_develop | 0.82774773 |
93 | MP0003329_amyloid_beta_deposits | 0.82458217 |
94 | MP0002168_other_aberrant_phenotype | 0.81806260 |
95 | MP0005595_abnormal_vascular_smooth | 0.79581671 |
96 | MP0002116_abnormal_craniofacial_bone | 0.79526584 |
97 | MP0003941_abnormal_skin_development | 0.79209623 |
98 | MP0004264_abnormal_extraembryonic_tissu | 0.78870695 |
99 | MP0003115_abnormal_respiratory_system | 0.78833700 |
100 | MP0002282_abnormal_trachea_morphology | 0.78773476 |
101 | MP0003045_fibrosis | 0.78092026 |
102 | MP0004036_abnormal_muscle_relaxation | 0.77693136 |
103 | MP0002653_abnormal_ependyma_morphology | 0.77504408 |
104 | MP0002078_abnormal_glucose_homeostasis | 0.77503709 |
105 | MP0005197_abnormal_uvea_morphology | 0.77480401 |
106 | MP0002925_abnormal_cardiovascular_devel | 0.76719542 |
107 | MP0004134_abnormal_chest_morphology | 0.76451535 |
108 | MP0006138_congestive_heart_failure | 0.76178313 |
109 | MP0000751_myopathy | 0.75673048 |
110 | MP0001533_abnormal_skeleton_physiology | 0.74952506 |
111 | MP0005621_abnormal_cell_physiology | 0.74548430 |
112 | MP0002998_abnormal_bone_remodeling | 0.74466009 |
113 | MP0000266_abnormal_heart_morphology | 0.73456870 |
114 | MP0003436_decreased_susceptibility_to | 0.72380652 |
115 | MP0002089_abnormal_postnatal_growth/wei | 0.71834675 |
116 | MP0009278_abnormal_bone_marrow | 0.71248178 |
117 | MP0005379_endocrine/exocrine_gland_phen | 0.71226646 |
118 | MP0004087_abnormal_muscle_fiber | 0.71185551 |
119 | MP0002092_abnormal_eye_morphology | 0.71134075 |
120 | MP0002128_abnormal_blood_circulation | 0.70784489 |
121 | MP0001175_abnormal_lung_morphology | 0.70618031 |
122 | MP0003448_altered_tumor_morphology | 0.69055186 |
123 | MP0002109_abnormal_limb_morphology | 0.68985384 |
124 | MP0000759_abnormal_skeletal_muscle | 0.68913217 |
125 | MP0003755_abnormal_palate_morphology | 0.68776261 |
126 | MP0002111_abnormal_tail_morphology | 0.68066312 |
127 | MP0003121_genomic_imprinting | 0.67512329 |
128 | MP0010630_abnormal_cardiac_muscle | 0.67506961 |
129 | MP0003172_abnormal_lysosome_physiology | 0.66708815 |
130 | MP0004858_abnormal_nervous_system | 0.66626593 |
131 | MP0004510_myositis | 0.63499780 |
132 | MP0002114_abnormal_axial_skeleton | 0.63481575 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 6.59146145 |
2 | Premature rupture of membranes (HP:0001788) | 5.95583791 |
3 | Cervical subluxation (HP:0003308) | 4.06371018 |
4 | Cerebral aneurysm (HP:0004944) | 3.89206439 |
5 | Hyperinsulinemic hypoglycemia (HP:0000825) | 3.78877216 |
6 | Aortic dissection (HP:0002647) | 3.61785765 |
7 | Soft skin (HP:0000977) | 3.61678668 |
8 | Ankle contracture (HP:0006466) | 3.58131284 |
9 | Abnormality of dentin (HP:0010299) | 3.51633627 |
10 | Vertebral compression fractures (HP:0002953) | 3.31273943 |
11 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 3.28408253 |
12 | Hypoglycemic seizures (HP:0002173) | 3.24428274 |
13 | Bladder diverticulum (HP:0000015) | 3.15814553 |
14 | Shallow orbits (HP:0000586) | 3.14169071 |
15 | Peritonitis (HP:0002586) | 3.14078410 |
16 | Aortic aneurysm (HP:0004942) | 3.09360570 |
17 | Hypoglycemic coma (HP:0001325) | 3.07866988 |
18 | Abnormal pancreas size (HP:0012094) | 3.03742867 |
19 | Atrophic scars (HP:0001075) | 2.91413436 |
20 | Ulnar bowing (HP:0003031) | 2.87929408 |
21 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.87403623 |
22 | Symptomatic seizures (HP:0011145) | 2.83936599 |
23 | Disproportionate tall stature (HP:0001519) | 2.79572209 |
24 | Hyperglycemia (HP:0003074) | 2.77075748 |
25 | Blue sclerae (HP:0000592) | 2.75588465 |
26 | Mitral regurgitation (HP:0001653) | 2.75200007 |
27 | Large for gestational age (HP:0001520) | 2.71727029 |
28 | Thoracolumbar scoliosis (HP:0002944) | 2.69719151 |
29 | Dilatation of the ascending aorta (HP:0005111) | 2.67075269 |
30 | Hepatoblastoma (HP:0002884) | 2.66140836 |
31 | Wormian bones (HP:0002645) | 2.64217088 |
32 | Fragile skin (HP:0001030) | 2.63781935 |
33 | Aneurysm (HP:0002617) | 2.60917766 |
34 | Neonatal short-limb short stature (HP:0008921) | 2.60265373 |
35 | Abnormality of the acetabulum (HP:0003170) | 2.59961043 |
36 | Broad face (HP:0000283) | 2.51775005 |
37 | Spinal rigidity (HP:0003306) | 2.51432558 |
38 | Broad metatarsal (HP:0001783) | 2.45211503 |
39 | Genu recurvatum (HP:0002816) | 2.44893683 |
40 | Slender build (HP:0001533) | 2.41640083 |
41 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.41334746 |
42 | Mucopolysacchariduria (HP:0008155) | 2.41334746 |
43 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.39869706 |
44 | Hyperacusis (HP:0010780) | 2.39504090 |
45 | Hand muscle atrophy (HP:0009130) | 2.39273447 |
46 | Aortic regurgitation (HP:0001659) | 2.38693951 |
47 | Short nail (HP:0001799) | 2.38661478 |
48 | Platyspondyly (HP:0000926) | 2.38104341 |
49 | Biconcave vertebral bodies (HP:0004586) | 2.37348751 |
50 | Type 1 muscle fiber predominance (HP:0003803) | 2.37022919 |
51 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.36981114 |
52 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.36981114 |
53 | Obstructive sleep apnea (HP:0002870) | 2.36357204 |
54 | Vascular tortuosity (HP:0004948) | 2.34585629 |
55 | Spondylolisthesis (HP:0003302) | 2.33649739 |
56 | Thin bony cortex (HP:0002753) | 2.32581894 |
57 | Mitral valve prolapse (HP:0001634) | 2.29656897 |
58 | Overgrowth (HP:0001548) | 2.29516222 |
59 | Achilles tendon contracture (HP:0001771) | 2.27925229 |
60 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.23209882 |
61 | Elbow flexion contracture (HP:0002987) | 2.22431676 |
62 | Hyperextensible skin (HP:0000974) | 2.22004046 |
63 | Arterial tortuosity (HP:0005116) | 2.19232674 |
64 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.19061090 |
65 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.19061090 |
66 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.19061090 |
67 | Upper limb amyotrophy (HP:0009129) | 2.16321005 |
68 | Distal upper limb amyotrophy (HP:0007149) | 2.16321005 |
69 | Dysostosis multiplex (HP:0000943) | 2.13524448 |
70 | Osteoarthritis (HP:0002758) | 2.11628446 |
71 | Follicular hyperkeratosis (HP:0007502) | 2.11015367 |
72 | Beaking of vertebral bodies (HP:0004568) | 2.10624947 |
73 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.10154852 |
74 | Joint laxity (HP:0001388) | 2.09229664 |
75 | Insulin resistance (HP:0000855) | 2.09122994 |
76 | Increased connective tissue (HP:0009025) | 2.09121521 |
77 | Ketoacidosis (HP:0001993) | 2.07549965 |
78 | Long toe (HP:0010511) | 2.07345411 |
79 | Abnormal delivery (HP:0001787) | 2.07078863 |
80 | Abnormality of the Achilles tendon (HP:0005109) | 2.06657283 |
81 | Distal lower limb amyotrophy (HP:0008944) | 2.06164797 |
82 | Congenital glaucoma (HP:0001087) | 2.05235774 |
83 | Wide anterior fontanel (HP:0000260) | 2.05041790 |
84 | Metaphyseal cupping (HP:0003021) | 2.04739120 |
85 | Hypoplastic ischia (HP:0003175) | 2.04583036 |
86 | Hypoventilation (HP:0002791) | 2.04228292 |
87 | Joint stiffness (HP:0001387) | 2.03651401 |
88 | Epiphyseal dysplasia (HP:0002656) | 2.03220027 |
89 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.01164131 |
90 | Coxa vara (HP:0002812) | 1.99326222 |
91 | Turricephaly (HP:0000262) | 1.98973166 |
92 | Exostoses (HP:0100777) | 1.98924530 |
93 | Atelectasis (HP:0100750) | 1.97713892 |
94 | Flat acetabular roof (HP:0003180) | 1.97294239 |
95 | Slender long bone (HP:0003100) | 1.96149938 |
96 | Ectopia lentis (HP:0001083) | 1.95873668 |
97 | Syringomyelia (HP:0003396) | 1.94303187 |
98 | Spinal cord lesions (HP:0100561) | 1.94303187 |
99 | Bowel diverticulosis (HP:0005222) | 1.94247176 |
100 | Premature skin wrinkling (HP:0100678) | 1.93600316 |
101 | Inguinal hernia (HP:0000023) | 1.92176228 |
102 | Missing ribs (HP:0000921) | 1.91856864 |
103 | Late onset (HP:0003584) | 1.91686882 |
104 | Camptodactyly of toe (HP:0001836) | 1.91357131 |
105 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.87913914 |
106 | Striae distensae (HP:0001065) | 1.87063040 |
107 | Mitral stenosis (HP:0001718) | 1.86994707 |
108 | Broad long bones (HP:0005622) | 1.86384376 |
109 | Nonimmune hydrops fetalis (HP:0001790) | 1.86315441 |
110 | Flat capital femoral epiphysis (HP:0003370) | 1.85803162 |
111 | Natal tooth (HP:0000695) | 1.85077355 |
112 | Breech presentation (HP:0001623) | 1.84045619 |
113 | Renal duplication (HP:0000075) | 1.83488400 |
114 | Thin ribs (HP:0000883) | 1.83007927 |
115 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.82777279 |
116 | Osteolytic defects of the hand bones (HP:0009699) | 1.82777279 |
117 | Ovoid vertebral bodies (HP:0003300) | 1.82602917 |
118 | Long palpebral fissure (HP:0000637) | 1.82038478 |
119 | Generalized amyotrophy (HP:0003700) | 1.81125320 |
120 | Asymmetric septal hypertrophy (HP:0001670) | 1.79660052 |
121 | Absent frontal sinuses (HP:0002688) | 1.78723471 |
122 | Osteopenia (HP:0000938) | 1.78595914 |
123 | Spinal cord compression (HP:0002176) | 1.77840576 |
124 | Mesomelia (HP:0003027) | 1.77436974 |
125 | Wrist flexion contracture (HP:0001239) | 1.76912203 |
126 | Hypoplasia of the odontoid process (HP:0003311) | 1.76745884 |
127 | Difficulty climbing stairs (HP:0003551) | 1.76485473 |
128 | Abnormality of the ischium (HP:0003174) | 1.76451014 |
129 | Coronal craniosynostosis (HP:0004440) | 1.76355104 |
130 | Arnold-Chiari malformation (HP:0002308) | 1.76346979 |
131 | Bowing of the arm (HP:0006488) | 1.75990841 |
132 | Bowed forearm bones (HP:0003956) | 1.75990841 |
133 | Hyperparathyroidism (HP:0000843) | 1.74532420 |
134 | Hypercortisolism (HP:0001578) | 1.74027476 |
135 | Radial bowing (HP:0002986) | 1.73056315 |
136 | Dislocated radial head (HP:0003083) | 1.73027427 |
137 | Cupped ribs (HP:0000887) | 1.72581989 |
138 | Increased variability in muscle fiber diameter (HP:0003557) | 1.72158698 |
139 | Arachnodactyly (HP:0001166) | 1.71489385 |
140 | Stridor (HP:0010307) | 1.71335379 |
141 | Abnormal ossification of hand bones (HP:0005921) | 1.71047034 |
142 | Aortic valve stenosis (HP:0001650) | 1.70458348 |
143 | Round ear (HP:0100830) | 1.69398743 |
144 | Venous abnormality (HP:0002624) | 1.69247541 |
145 | Mild short stature (HP:0003502) | 1.64982302 |
146 | Abnormality of skull ossification (HP:0002703) | 1.64340328 |
147 | Vertebral arch anomaly (HP:0008438) | 1.63941236 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.14845999 |
2 | ERN1 | 4.03779912 |
3 | PASK | 3.93974978 |
4 | INSRR | 3.21289378 |
5 | PKN2 | 2.96205858 |
6 | PDGFRA | 2.88669260 |
7 | MAPK15 | 2.74750565 |
8 | FLT3 | 2.55132836 |
9 | ICK | 2.52325129 |
10 | SMG1 | 2.32181633 |
11 | DDR2 | 2.31772601 |
12 | LATS1 | 2.25044271 |
13 | PRPF4B | 2.22994647 |
14 | PRKD3 | 2.20512256 |
15 | TTN | 2.15728857 |
16 | RIPK1 | 2.02884890 |
17 | PTK2 | 1.80802538 |
18 | EPHA3 | 1.74013017 |
19 | LATS2 | 1.71826740 |
20 | HIPK2 | 1.70568315 |
21 | SIK1 | 1.70061543 |
22 | PTK6 | 1.67097225 |
23 | BRSK2 | 1.61779206 |
24 | TESK1 | 1.58565039 |
25 | STK3 | 1.52492111 |
26 | MAP2K3 | 1.47567276 |
27 | PAK4 | 1.33306835 |
28 | MAP3K3 | 1.32996125 |
29 | STK38L | 1.28230089 |
30 | TAOK3 | 1.28056142 |
31 | EPHA2 | 1.27775179 |
32 | MET | 1.25186541 |
33 | MARK2 | 1.23020493 |
34 | STK38 | 1.20489811 |
35 | MAP3K10 | 1.16596449 |
36 | PAK3 | 1.14153233 |
37 | NTRK1 | 1.10888867 |
38 | RPS6KA4 | 1.10704857 |
39 | KSR2 | 1.10431099 |
40 | SCYL2 | 1.09657688 |
41 | PIM2 | 1.06360576 |
42 | PAK2 | 1.05757097 |
43 | TYRO3 | 1.03834562 |
44 | MAP3K6 | 1.03371205 |
45 | MAP3K7 | 1.02723481 |
46 | CDC42BPA | 1.02352957 |
47 | MAP3K13 | 1.02164104 |
48 | DYRK1B | 1.01102008 |
49 | TAOK2 | 0.99694564 |
50 | MTOR | 0.99474088 |
51 | PRKG2 | 0.99291947 |
52 | DMPK | 0.97370860 |
53 | FER | 0.94994187 |
54 | LRRK2 | 0.94491508 |
55 | JAK3 | 0.91735908 |
56 | NEK9 | 0.91094752 |
57 | ILK | 0.89138379 |
58 | TGFBR2 | 0.89031670 |
59 | ARAF | 0.87876533 |
60 | MST1R | 0.87578060 |
61 | MYLK | 0.86526778 |
62 | CDK8 | 0.81793125 |
63 | LMTK2 | 0.78998066 |
64 | WNK4 | 0.76569460 |
65 | EPHB2 | 0.76189704 |
66 | MAP2K2 | 0.75198109 |
67 | MAPKAPK3 | 0.74222591 |
68 | PDPK1 | 0.71281431 |
69 | WNK1 | 0.69340733 |
70 | PDGFRB | 0.69156573 |
71 | PIK3CG | 0.66525546 |
72 | CAMKK2 | 0.65796435 |
73 | CDK12 | 0.65379655 |
74 | MAP3K1 | 0.65113712 |
75 | TRPM7 | 0.64888403 |
76 | ROCK2 | 0.63781207 |
77 | FGFR3 | 0.63211584 |
78 | KDR | 0.62654290 |
79 | DYRK3 | 0.61256820 |
80 | STK10 | 0.61178281 |
81 | PRKD2 | 0.60593753 |
82 | LIMK1 | 0.60592958 |
83 | BCKDK | 0.60472492 |
84 | BRSK1 | 0.59938028 |
85 | RPS6KC1 | 0.58287377 |
86 | RPS6KL1 | 0.58287377 |
87 | ERBB4 | 0.57828890 |
88 | ZAP70 | 0.57427979 |
89 | CHUK | 0.57231141 |
90 | NLK | 0.56670263 |
91 | TIE1 | 0.55497676 |
92 | MOS | 0.54880985 |
93 | EIF2AK3 | 0.54505809 |
94 | EPHB1 | 0.53959953 |
95 | TYK2 | 0.53504977 |
96 | BRD4 | 0.53465499 |
97 | MAPK7 | 0.53133540 |
98 | ERBB3 | 0.51681351 |
99 | PRKCI | 0.51641066 |
100 | TGFBR1 | 0.51351992 |
101 | CLK1 | 0.51131421 |
102 | TBK1 | 0.48666940 |
103 | MELK | 0.48641591 |
104 | SIK2 | 0.48620656 |
105 | PRKCH | 0.47471027 |
106 | AKT3 | 0.45643547 |
107 | CDK9 | 0.44900177 |
108 | ROCK1 | 0.44869203 |
109 | MAP2K1 | 0.44163620 |
110 | IRAK1 | 0.43249097 |
111 | FGFR1 | 0.42584508 |
112 | MAPKAPK2 | 0.41347430 |
113 | MAP3K8 | 0.41194904 |
114 | PAK1 | 0.41168555 |
115 | EEF2K | 0.41025414 |
116 | PRKD1 | 0.40566325 |
117 | IRAK3 | 0.40521175 |
118 | TAOK1 | 0.39769799 |
119 | FGFR4 | 0.39461212 |
120 | BRAF | 0.39280222 |
121 | BMX | 0.39153791 |
122 | STK24 | 0.38931447 |
123 | PTK2B | 0.38914518 |
124 | FRK | 0.38845794 |
125 | KSR1 | 0.37815503 |
126 | RPS6KA2 | 0.36949034 |
127 | RET | 0.36450035 |
128 | CDK7 | 0.35078867 |
129 | CAMK1G | 0.33883263 |
130 | MAPK11 | 0.33566699 |
131 | RPS6KA6 | 0.33325374 |
132 | MAP3K11 | 0.33307940 |
133 | GSK3A | 0.33135273 |
134 | MAP3K2 | 0.32904448 |
135 | WNK3 | 0.32692383 |
136 | JAK1 | 0.32677253 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 5.75591615 |
2 | Protein export_Homo sapiens_hsa03060 | 4.19487228 |
3 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 3.62123123 |
4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.41328612 |
5 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.29077953 |
6 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 2.09334659 |
7 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.05770716 |
8 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.99204076 |
9 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.85214591 |
10 | Focal adhesion_Homo sapiens_hsa04510 | 1.85147435 |
11 | Other glycan degradation_Homo sapiens_hsa00511 | 1.83722635 |
12 | Lysosome_Homo sapiens_hsa04142 | 1.74691905 |
13 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.69951294 |
14 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.57948545 |
15 | Bladder cancer_Homo sapiens_hsa05219 | 1.55716312 |
16 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.46943673 |
17 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.46688584 |
18 | Galactose metabolism_Homo sapiens_hsa00052 | 1.41062549 |
19 | Insulin secretion_Homo sapiens_hsa04911 | 1.40512015 |
20 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.37499728 |
21 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.35775822 |
22 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.35155514 |
23 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.32970837 |
24 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.27445863 |
25 | Amoebiasis_Homo sapiens_hsa05146 | 1.26207513 |
26 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.22909259 |
27 | Adherens junction_Homo sapiens_hsa04520 | 1.22417303 |
28 | Insulin resistance_Homo sapiens_hsa04931 | 1.19139796 |
29 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.17553476 |
30 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.16779410 |
31 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.16607926 |
32 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.14950548 |
33 | Glioma_Homo sapiens_hsa05214 | 1.13636799 |
34 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.11417036 |
35 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.10203334 |
36 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.06461737 |
37 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.05436553 |
38 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.05156701 |
39 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.03988917 |
40 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.03164121 |
41 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.01168954 |
42 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.96128501 |
43 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.92818799 |
44 | Thyroid cancer_Homo sapiens_hsa05216 | 0.92234548 |
45 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.91403161 |
46 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.91218639 |
47 | Axon guidance_Homo sapiens_hsa04360 | 0.90844959 |
48 | Legionellosis_Homo sapiens_hsa05134 | 0.90438252 |
49 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.88806588 |
50 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.88585783 |
51 | * Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.86721387 |
52 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.85665469 |
53 | Melanogenesis_Homo sapiens_hsa04916 | 0.85620080 |
54 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.84815567 |
55 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.84742815 |
56 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.84369277 |
57 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.84145679 |
58 | Malaria_Homo sapiens_hsa05144 | 0.83999250 |
59 | Endocytosis_Homo sapiens_hsa04144 | 0.83805519 |
60 | Cell cycle_Homo sapiens_hsa04110 | 0.83710564 |
61 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.83526637 |
62 | Prostate cancer_Homo sapiens_hsa05215 | 0.83447746 |
63 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.83414881 |
64 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.82927085 |
65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.82176672 |
66 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.80772505 |
67 | HTLV-I infection_Homo sapiens_hsa05166 | 0.80643699 |
68 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.79424743 |
69 | Hepatitis C_Homo sapiens_hsa05160 | 0.79354832 |
70 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.78734119 |
71 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.78712674 |
72 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77074502 |
73 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.76795919 |
74 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.76447333 |
75 | Tight junction_Homo sapiens_hsa04530 | 0.75653495 |
76 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75351324 |
77 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.72403317 |
78 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.71721907 |
79 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.70525191 |
80 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.70512140 |
81 | Salmonella infection_Homo sapiens_hsa05132 | 0.69351476 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.67574209 |
83 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.66706557 |
84 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66582200 |
85 | Phagosome_Homo sapiens_hsa04145 | 0.66025440 |
86 | Lysine degradation_Homo sapiens_hsa00310 | 0.65859445 |
87 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.65580732 |
88 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.65168174 |
89 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.62798746 |
90 | Gap junction_Homo sapiens_hsa04540 | 0.61695729 |
91 | Apoptosis_Homo sapiens_hsa04210 | 0.59923321 |
92 | Pathways in cancer_Homo sapiens_hsa05200 | 0.59717086 |
93 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.59334875 |
94 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.57741596 |
95 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.56915154 |
96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.56852507 |
97 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56565340 |
98 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.56557893 |
99 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.56380374 |
100 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.55884999 |
101 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.55363579 |
102 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.54447079 |
103 | Melanoma_Homo sapiens_hsa05218 | 0.54208529 |
104 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.53198804 |
105 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.53122764 |
106 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.51775785 |
107 | Platelet activation_Homo sapiens_hsa04611 | 0.51568257 |
108 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.49537748 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.49234378 |
110 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.48647158 |
111 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.48577706 |
112 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.48548304 |
113 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.48519322 |
114 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48114979 |
115 | Colorectal cancer_Homo sapiens_hsa05210 | 0.48012512 |
116 | Prion diseases_Homo sapiens_hsa05020 | 0.47789000 |
117 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.47771707 |
118 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.47473251 |
119 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.47342897 |
120 | Hepatitis B_Homo sapiens_hsa05161 | 0.46831522 |
121 | Cocaine addiction_Homo sapiens_hsa05030 | 0.46183075 |
122 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46121571 |
123 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.45910321 |
124 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.45571848 |
125 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.45376649 |
126 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.42187672 |
127 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.41448865 |
128 | Viral myocarditis_Homo sapiens_hsa05416 | 0.41233596 |
129 | Shigellosis_Homo sapiens_hsa05131 | 0.39297106 |
130 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.38814145 |