Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic metaphase plate congression (GO:0007080) | 4.48932741 |
2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.38738831 |
3 | DNA replication checkpoint (GO:0000076) | 4.33531328 |
4 | CENP-A containing nucleosome assembly (GO:0034080) | 4.26535786 |
5 | proteasome assembly (GO:0043248) | 4.24042785 |
6 | DNA strand elongation (GO:0022616) | 4.19128096 |
7 | mitotic sister chromatid segregation (GO:0000070) | 4.18056449 |
8 | DNA replication initiation (GO:0006270) | 4.16116426 |
9 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.08082639 |
10 | chromatin remodeling at centromere (GO:0031055) | 4.08068422 |
11 | ribosomal small subunit assembly (GO:0000028) | 4.03294538 |
12 | purine nucleobase biosynthetic process (GO:0009113) | 3.95672318 |
13 | sister chromatid segregation (GO:0000819) | 3.95472873 |
14 | nucleobase biosynthetic process (GO:0046112) | 3.93300163 |
15 | metaphase plate congression (GO:0051310) | 3.89041172 |
16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.88690594 |
17 | maturation of SSU-rRNA (GO:0030490) | 3.88650311 |
18 | formation of translation preinitiation complex (GO:0001731) | 3.88146935 |
19 | kinetochore assembly (GO:0051382) | 3.87008650 |
20 | DNA deamination (GO:0045006) | 3.86471620 |
21 | termination of RNA polymerase III transcription (GO:0006386) | 3.83312264 |
22 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.83312264 |
23 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.82912413 |
24 | nuclear pore organization (GO:0006999) | 3.81593303 |
25 | nuclear pore complex assembly (GO:0051292) | 3.80088238 |
26 | DNA replication-independent nucleosome organization (GO:0034724) | 3.80056302 |
27 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.80056302 |
28 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.78825138 |
29 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.78825138 |
30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.77062445 |
31 | ribosome biogenesis (GO:0042254) | 3.76979773 |
32 | kinetochore organization (GO:0051383) | 3.76685062 |
33 | telomere maintenance via recombination (GO:0000722) | 3.75117447 |
34 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.72721176 |
35 | * 7-methylguanosine mRNA capping (GO:0006370) | 3.72249547 |
36 | protein localization to kinetochore (GO:0034501) | 3.69555497 |
37 | protein K6-linked ubiquitination (GO:0085020) | 3.69145570 |
38 | spliceosomal snRNP assembly (GO:0000387) | 3.69082738 |
39 | * 7-methylguanosine RNA capping (GO:0009452) | 3.66140557 |
40 | * RNA capping (GO:0036260) | 3.66140557 |
41 | establishment of chromosome localization (GO:0051303) | 3.63494109 |
42 | ribosome assembly (GO:0042255) | 3.58325135 |
43 | rRNA modification (GO:0000154) | 3.57975527 |
44 | mitotic recombination (GO:0006312) | 3.55755908 |
45 | protein deneddylation (GO:0000338) | 3.55453872 |
46 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.54234489 |
47 | negative regulation of ligase activity (GO:0051352) | 3.54234489 |
48 | * transcription-coupled nucleotide-excision repair (GO:0006283) | 3.53223010 |
49 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.51340348 |
50 | histone exchange (GO:0043486) | 3.51101890 |
51 | viral mRNA export from host cell nucleus (GO:0046784) | 3.50920535 |
52 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.50282437 |
53 | mitotic sister chromatid cohesion (GO:0007064) | 3.48659091 |
54 | cullin deneddylation (GO:0010388) | 3.47471149 |
55 | IMP biosynthetic process (GO:0006188) | 3.46946099 |
56 | termination of RNA polymerase I transcription (GO:0006363) | 3.43339494 |
57 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.41587119 |
58 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.41587119 |
59 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.40943596 |
60 | non-recombinational repair (GO:0000726) | 3.40943596 |
61 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.39734977 |
62 | ribosomal large subunit biogenesis (GO:0042273) | 3.39073005 |
63 | mitotic chromosome condensation (GO:0007076) | 3.38374861 |
64 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.35680085 |
65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.35677039 |
66 | maturation of 5.8S rRNA (GO:0000460) | 3.35556566 |
67 | transcription from RNA polymerase I promoter (GO:0006360) | 3.32291426 |
68 | establishment of integrated proviral latency (GO:0075713) | 3.32223426 |
69 | mitotic nuclear envelope disassembly (GO:0007077) | 3.31430993 |
70 | rRNA processing (GO:0006364) | 3.31349724 |
71 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.31316999 |
72 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.31316999 |
73 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.31316999 |
74 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.30887818 |
75 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.29991453 |
76 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.29991453 |
77 | DNA unwinding involved in DNA replication (GO:0006268) | 3.28062295 |
78 | telomere maintenance via telomere lengthening (GO:0010833) | 3.25054364 |
79 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.24297701 |
80 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.24297701 |
81 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.23106819 |
82 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.22593186 |
83 | spliceosomal complex assembly (GO:0000245) | 3.22243414 |
84 | DNA ligation (GO:0006266) | 3.22235112 |
85 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.21778477 |
86 | regulation of centriole replication (GO:0046599) | 3.21708320 |
87 | protein localization to chromosome, centromeric region (GO:0071459) | 3.21276801 |
88 | histone H2A acetylation (GO:0043968) | 3.20450612 |
89 | rRNA metabolic process (GO:0016072) | 3.19714139 |
90 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.17370233 |
91 | cell cycle G1/S phase transition (GO:0044843) | 3.17370233 |
92 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.17110909 |
93 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.17110909 |
94 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.16970885 |
95 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.16540924 |
96 | regulation of mitochondrial translation (GO:0070129) | 3.16387271 |
97 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.15245810 |
98 | positive regulation of ligase activity (GO:0051351) | 3.14787644 |
99 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.14539449 |
100 | * transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.12397153 |
101 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.11620122 |
102 | ribosomal small subunit biogenesis (GO:0042274) | 3.11012266 |
103 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.09270051 |
104 | mitotic spindle checkpoint (GO:0071174) | 3.08401383 |
105 | regulation of centrosome cycle (GO:0046605) | 3.07293792 |
106 | pseudouridine synthesis (GO:0001522) | 3.06409865 |
107 | spindle checkpoint (GO:0031577) | 3.05958754 |
108 | regulation of chromosome segregation (GO:0051983) | 3.05346385 |
109 | DNA double-strand break processing (GO:0000729) | 3.03833953 |
110 | mitochondrial RNA metabolic process (GO:0000959) | 3.03728891 |
111 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.03728374 |
112 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.02856829 |
113 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.02632998 |
114 | replication fork processing (GO:0031297) | 3.02632379 |
115 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.01990985 |
116 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.01694352 |
117 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.01374701 |
118 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.01143266 |
119 | nuclear envelope disassembly (GO:0051081) | 3.00693748 |
120 | membrane disassembly (GO:0030397) | 3.00693748 |
121 | tRNA aminoacylation (GO:0043039) | 3.00654540 |
122 | amino acid activation (GO:0043038) | 3.00654540 |
123 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.00397577 |
124 | negative regulation of sister chromatid segregation (GO:0033046) | 3.00397577 |
125 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.00397577 |
126 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.00397577 |
127 | regulation of DNA endoreduplication (GO:0032875) | 2.99361719 |
128 | DNA-templated transcription, termination (GO:0006353) | 2.99298401 |
129 | IMP metabolic process (GO:0046040) | 2.98887494 |
130 | negative regulation of chromosome segregation (GO:0051985) | 2.98079088 |
131 | * DNA-templated transcription, elongation (GO:0006354) | 2.97809331 |
132 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.97787439 |
133 | tRNA aminoacylation for protein translation (GO:0006418) | 2.97181950 |
134 | establishment of viral latency (GO:0019043) | 2.97030013 |
135 | meiotic chromosome segregation (GO:0045132) | 2.94906607 |
136 | regulation of translational fidelity (GO:0006450) | 2.93669257 |
137 | positive regulation of chromosome segregation (GO:0051984) | 2.90115451 |
138 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.89707836 |
139 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.89707836 |
140 | isotype switching (GO:0045190) | 2.89707836 |
141 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.88295737 |
142 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.88295737 |
143 | DNA topological change (GO:0006265) | 2.87551088 |
144 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.87306680 |
145 | mitotic spindle assembly checkpoint (GO:0007094) | 2.87181749 |
146 | L-serine metabolic process (GO:0006563) | 2.87050140 |
147 | chromosome segregation (GO:0007059) | 2.85566911 |
148 | spindle assembly checkpoint (GO:0071173) | 2.84273011 |
149 | regulation of sister chromatid segregation (GO:0033045) | 2.83470264 |
150 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.83470264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.09078787 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.43077963 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.20769278 |
4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.72090764 |
5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.69752094 |
6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.54583551 |
7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.49116606 |
8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.46748093 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.34510913 |
10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.20471468 |
11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.20280555 |
12 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.16543156 |
13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.94874578 |
14 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.93957591 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.91889684 |
16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.88509017 |
17 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.84229775 |
18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.83356305 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.79199738 |
20 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.61155618 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50077238 |
22 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.44522309 |
23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.38541174 |
24 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.38531936 |
25 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.37349990 |
26 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.20903269 |
27 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.18763176 |
28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.16583023 |
29 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.16307964 |
30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.10886493 |
31 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.10466052 |
32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.10172070 |
33 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.08586947 |
34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.04565038 |
35 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.04390656 |
36 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.98325572 |
37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.94788703 |
38 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.94305122 |
39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.91297271 |
40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.87974214 |
41 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.86457141 |
42 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.84798005 |
43 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.79333714 |
44 | * POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74817337 |
45 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.74391210 |
46 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.74296450 |
47 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.71423180 |
48 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.68121318 |
49 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.67549305 |
50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.67107004 |
51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63901170 |
52 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.62937652 |
53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.60929388 |
54 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.58195199 |
55 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53917551 |
56 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.51106315 |
57 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.50736615 |
58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.49397604 |
59 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.40572125 |
60 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.38624843 |
61 | EWS_26573619_Chip-Seq_HEK293_Human | 1.37431638 |
62 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35213339 |
63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.30720071 |
64 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29369179 |
65 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28103492 |
66 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.24897900 |
67 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.24256819 |
68 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.23564479 |
69 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.22776115 |
70 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22118761 |
71 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.19120067 |
72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18443047 |
73 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.18114973 |
74 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.16935708 |
75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.15780105 |
76 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.12494307 |
77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.11912215 |
78 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.11070896 |
79 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.09910520 |
80 | VDR_22108803_ChIP-Seq_LS180_Human | 1.09593354 |
81 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.09354693 |
82 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.08784582 |
83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.06693657 |
84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.05115955 |
85 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.03466192 |
86 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.01272861 |
87 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99493541 |
88 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.99339414 |
89 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.99258600 |
90 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.97607227 |
91 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.93632558 |
92 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.91326953 |
93 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90728656 |
94 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.90171447 |
95 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.89775911 |
96 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.88263583 |
97 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.87079576 |
98 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.86074772 |
99 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.84518566 |
100 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.83795404 |
101 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.83529254 |
102 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.82839864 |
103 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.79960618 |
104 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79946741 |
105 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.79355098 |
106 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.79038345 |
107 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.77838163 |
108 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.77435711 |
109 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.76568815 |
110 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.76206020 |
111 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75387324 |
112 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.74267794 |
113 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.72115438 |
114 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.71741405 |
115 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.68441939 |
116 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.67320673 |
117 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.62062498 |
118 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.61706434 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.18275065 |
2 | MP0010094_abnormal_chromosome_stability | 4.35632260 |
3 | MP0004957_abnormal_blastocyst_morpholog | 4.23489470 |
4 | MP0003077_abnormal_cell_cycle | 3.89922812 |
5 | MP0003111_abnormal_nucleus_morphology | 3.89366023 |
6 | MP0008058_abnormal_DNA_repair | 3.67235485 |
7 | MP0008057_abnormal_DNA_replication | 3.61718938 |
8 | MP0003718_maternal_effect | 2.84975313 |
9 | MP0008932_abnormal_embryonic_tissue | 2.84563159 |
10 | MP0008007_abnormal_cellular_replicative | 2.84205769 |
11 | MP0008877_abnormal_DNA_methylation | 2.50470472 |
12 | MP0003123_paternal_imprinting | 2.44591992 |
13 | MP0006292_abnormal_olfactory_placode | 2.39192994 |
14 | MP0000350_abnormal_cell_proliferation | 1.92927488 |
15 | MP0003786_premature_aging | 1.88757538 |
16 | MP0002132_abnormal_respiratory_system | 1.88596820 |
17 | MP0001730_embryonic_growth_arrest | 1.87289076 |
18 | MP0004133_heterotaxia | 1.83530487 |
19 | MP0003121_genomic_imprinting | 1.79790870 |
20 | MP0002396_abnormal_hematopoietic_system | 1.78085107 |
21 | MP0008789_abnormal_olfactory_epithelium | 1.75953889 |
22 | MP0003315_abnormal_perineum_morphology | 1.75348005 |
23 | MP0010030_abnormal_orbit_morphology | 1.54799196 |
24 | MP0002210_abnormal_sex_determination | 1.47344091 |
25 | MP0001697_abnormal_embryo_size | 1.44703685 |
26 | MP0005380_embryogenesis_phenotype | 1.42275164 |
27 | MP0001672_abnormal_embryogenesis/_devel | 1.42275164 |
28 | MP0000490_abnormal_crypts_of | 1.37988967 |
29 | MP0002102_abnormal_ear_morphology | 1.35851236 |
30 | MP0002938_white_spotting | 1.33840502 |
31 | MP0002085_abnormal_embryonic_tissue | 1.33152278 |
32 | MP0006072_abnormal_retinal_apoptosis | 1.27580233 |
33 | MP0002080_prenatal_lethality | 1.26799715 |
34 | MP0005394_taste/olfaction_phenotype | 1.26345790 |
35 | MP0005499_abnormal_olfactory_system | 1.26345790 |
36 | MP0000313_abnormal_cell_death | 1.22836586 |
37 | MP0001293_anophthalmia | 1.21419680 |
38 | MP0001529_abnormal_vocalization | 1.20928601 |
39 | MP0003806_abnormal_nucleotide_metabolis | 1.20837015 |
40 | MP0002084_abnormal_developmental_patter | 1.19813521 |
41 | MP0003890_abnormal_embryonic-extraembry | 1.19702822 |
42 | MP0003984_embryonic_growth_retardation | 1.19450454 |
43 | MP0001145_abnormal_male_reproductive | 1.18240584 |
44 | MP0003937_abnormal_limbs/digits/tail_de | 1.17184404 |
45 | MP0000653_abnormal_sex_gland | 1.15419351 |
46 | MP0001119_abnormal_female_reproductive | 1.14985769 |
47 | MP0002088_abnormal_embryonic_growth/wei | 1.14866961 |
48 | MP0002277_abnormal_respiratory_mucosa | 1.13858030 |
49 | MP0002019_abnormal_tumor_incidence | 1.13423748 |
50 | MP0003186_abnormal_redox_activity | 1.13421342 |
51 | MP0001929_abnormal_gametogenesis | 1.12791894 |
52 | MP0004808_abnormal_hematopoietic_stem | 1.10704504 |
53 | MP0000049_abnormal_middle_ear | 1.07463399 |
54 | MP0009333_abnormal_splenocyte_physiolog | 1.06615222 |
55 | MP0009672_abnormal_birth_weight | 1.06390320 |
56 | MP0002653_abnormal_ependyma_morphology | 1.02339556 |
57 | MP0009697_abnormal_copulation | 1.01285883 |
58 | MP0004233_abnormal_muscle_weight | 1.00394658 |
59 | MP0001188_hyperpigmentation | 0.99309184 |
60 | MP0003119_abnormal_digestive_system | 0.98899837 |
61 | MP0002160_abnormal_reproductive_system | 0.94950779 |
62 | MP0005253_abnormal_eye_physiology | 0.94560932 |
63 | MP0002697_abnormal_eye_size | 0.92689802 |
64 | MP0001346_abnormal_lacrimal_gland | 0.92136248 |
65 | MP0002111_abnormal_tail_morphology | 0.91276430 |
66 | MP0003698_abnormal_male_reproductive | 0.91180585 |
67 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89698973 |
68 | MP0005408_hypopigmentation | 0.89061720 |
69 | MP0004197_abnormal_fetal_growth/weight/ | 0.88936972 |
70 | MP0003941_abnormal_skin_development | 0.88682433 |
71 | MP0005389_reproductive_system_phenotype | 0.88468746 |
72 | MP0003763_abnormal_thymus_physiology | 0.87859388 |
73 | MP0005084_abnormal_gallbladder_morpholo | 0.87102102 |
74 | MP0010307_abnormal_tumor_latency | 0.83537187 |
75 | MP0008260_abnormal_autophagy | 0.82369929 |
76 | MP0005379_endocrine/exocrine_gland_phen | 0.82333858 |
77 | MP0005187_abnormal_penis_morphology | 0.82238982 |
78 | MP0002086_abnormal_extraembryonic_tissu | 0.81696313 |
79 | MP0005377_hearing/vestibular/ear_phenot | 0.80903997 |
80 | MP0003878_abnormal_ear_physiology | 0.80903997 |
81 | MP0000647_abnormal_sebaceous_gland | 0.80810917 |
82 | MP0000358_abnormal_cell_content/ | 0.79902472 |
83 | MP0001286_abnormal_eye_development | 0.79536484 |
84 | MP0003861_abnormal_nervous_system | 0.78695584 |
85 | MP0002638_abnormal_pupillary_reflex | 0.78307957 |
86 | MP0002233_abnormal_nose_morphology | 0.77733769 |
87 | MP0003943_abnormal_hepatobiliary_system | 0.77598028 |
88 | MP0009703_decreased_birth_body | 0.76459230 |
89 | MP0005391_vision/eye_phenotype | 0.76425304 |
90 | MP0001324_abnormal_eye_pigmentation | 0.76136083 |
91 | MP0008995_early_reproductive_senescence | 0.75689455 |
92 | MP0005395_other_phenotype | 0.75563759 |
93 | MP0009250_abnormal_appendicular_skeleto | 0.75042573 |
94 | MP0005220_abnormal_exocrine_pancreas | 0.73512855 |
95 | MP0001905_abnormal_dopamine_level | 0.73246948 |
96 | MP0000703_abnormal_thymus_morphology | 0.73172470 |
97 | MP0003122_maternal_imprinting | 0.72601452 |
98 | MP0003136_yellow_coat_color | 0.72543405 |
99 | MP0005367_renal/urinary_system_phenotyp | 0.72287952 |
100 | MP0000516_abnormal_urinary_system | 0.72287952 |
101 | MP0003938_abnormal_ear_development | 0.71014494 |
102 | MP0001727_abnormal_embryo_implantation | 0.69857068 |
103 | MP0006035_abnormal_mitochondrial_morpho | 0.69830284 |
104 | MP0003221_abnormal_cardiomyocyte_apopto | 0.69699537 |
105 | MP0002398_abnormal_bone_marrow | 0.69281281 |
106 | MP0003755_abnormal_palate_morphology | 0.68921659 |
107 | MP0002234_abnormal_pharynx_morphology | 0.68720180 |
108 | MP0002009_preneoplasia | 0.68367072 |
109 | MP0002161_abnormal_fertility/fecundity | 0.67573423 |
110 | MP0003646_muscle_fatigue | 0.67519245 |
111 | MP0003942_abnormal_urinary_system | 0.67131329 |
112 | MP0000689_abnormal_spleen_morphology | 0.66630903 |
113 | MP0000566_synostosis | 0.66618425 |
114 | MP0003787_abnormal_imprinting | 0.66575353 |
115 | MP0006036_abnormal_mitochondrial_physio | 0.65883641 |
116 | MP0000631_abnormal_neuroendocrine_gland | 0.65865405 |
117 | MP0001919_abnormal_reproductive_system | 0.65823434 |
118 | MP0002722_abnormal_immune_system | 0.65710569 |
119 | MP0002095_abnormal_skin_pigmentation | 0.65590407 |
120 | MP0005384_cellular_phenotype | 0.65167451 |
121 | MP0009379_abnormal_foot_pigmentation | 0.64595801 |
122 | MP0003699_abnormal_female_reproductive | 0.64280352 |
123 | MP0002751_abnormal_autonomic_nervous | 0.63236674 |
124 | MP0001299_abnormal_eye_distance/ | 0.62282209 |
125 | MP0001485_abnormal_pinna_reflex | 0.62281513 |
126 | MP0001661_extended_life_span | 0.62270358 |
127 | MP0000372_irregular_coat_pigmentation | 0.61888089 |
128 | MP0002163_abnormal_gland_morphology | 0.61239355 |
129 | MP0000678_abnormal_parathyroid_gland | 0.60877379 |
130 | MP0010352_gastrointestinal_tract_polyps | 0.60740994 |
131 | MP0000858_altered_metastatic_potential | 0.58967144 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.25916780 |
2 | Breast hypoplasia (HP:0003187) | 4.10635895 |
3 | Degeneration of anterior horn cells (HP:0002398) | 3.57121751 |
4 | Abnormality of the anterior horn cell (HP:0006802) | 3.57121751 |
5 | Patellar aplasia (HP:0006443) | 3.48236586 |
6 | Carpal bone hypoplasia (HP:0001498) | 3.31444642 |
7 | Cerebral hypomyelination (HP:0006808) | 3.31206255 |
8 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.30568788 |
9 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.14817808 |
10 | Rough bone trabeculation (HP:0100670) | 3.14678960 |
11 | Stenosis of the external auditory canal (HP:0000402) | 3.14611174 |
12 | Abnormal number of erythroid precursors (HP:0012131) | 3.13778656 |
13 | Oral leukoplakia (HP:0002745) | 3.07047345 |
14 | Abnormal lung lobation (HP:0002101) | 2.95707827 |
15 | Aplastic anemia (HP:0001915) | 2.94717425 |
16 | Microretrognathia (HP:0000308) | 2.88755837 |
17 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.83339793 |
18 | Chromsome breakage (HP:0040012) | 2.83195718 |
19 | Reticulocytopenia (HP:0001896) | 2.82016073 |
20 | Abnormality of the labia minora (HP:0012880) | 2.78981852 |
21 | Colon cancer (HP:0003003) | 2.75215043 |
22 | Abnormality of glycolysis (HP:0004366) | 2.69331855 |
23 | Increased serum pyruvate (HP:0003542) | 2.69331855 |
24 | Meckel diverticulum (HP:0002245) | 2.66759426 |
25 | Microvesicular hepatic steatosis (HP:0001414) | 2.64782794 |
26 | Glossoptosis (HP:0000162) | 2.64694418 |
27 | Irregular epiphyses (HP:0010582) | 2.62783632 |
28 | Abnormality of the preputium (HP:0100587) | 2.62413190 |
29 | Abnormality of the ileum (HP:0001549) | 2.53636156 |
30 | Facial hemangioma (HP:0000329) | 2.53590869 |
31 | Abnormality of the carotid arteries (HP:0005344) | 2.53205630 |
32 | Ependymoma (HP:0002888) | 2.46493396 |
33 | Ectopic kidney (HP:0000086) | 2.42529218 |
34 | Abnormal trabecular bone morphology (HP:0100671) | 2.40933171 |
35 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.39762145 |
36 | Absent radius (HP:0003974) | 2.39029210 |
37 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.38455132 |
38 | Acute encephalopathy (HP:0006846) | 2.37219312 |
39 | Type I transferrin isoform profile (HP:0003642) | 2.34135443 |
40 | Pancreatic cysts (HP:0001737) | 2.33579397 |
41 | Clubbing of toes (HP:0100760) | 2.32614704 |
42 | Small intestinal stenosis (HP:0012848) | 2.32082370 |
43 | Duodenal stenosis (HP:0100867) | 2.32082370 |
44 | Premature graying of hair (HP:0002216) | 2.27810828 |
45 | Multiple enchondromatosis (HP:0005701) | 2.26230840 |
46 | Selective tooth agenesis (HP:0001592) | 2.25580239 |
47 | Long clavicles (HP:0000890) | 2.25116178 |
48 | Volvulus (HP:0002580) | 2.24070516 |
49 | Abnormality of chromosome stability (HP:0003220) | 2.23800010 |
50 | Aplasia involving forearm bones (HP:0009822) | 2.23786334 |
51 | Absent forearm bone (HP:0003953) | 2.23786334 |
52 | Supernumerary spleens (HP:0009799) | 2.22518860 |
53 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.20935135 |
54 | Increased hepatocellular lipid droplets (HP:0006565) | 2.18369448 |
55 | Myelodysplasia (HP:0002863) | 2.17663245 |
56 | Increased nuchal translucency (HP:0010880) | 2.13053101 |
57 | Bone marrow hypocellularity (HP:0005528) | 2.11786261 |
58 | Type 2 muscle fiber atrophy (HP:0003554) | 2.11582422 |
59 | Lipid accumulation in hepatocytes (HP:0006561) | 2.10735381 |
60 | Sloping forehead (HP:0000340) | 2.10696008 |
61 | Secondary amenorrhea (HP:0000869) | 2.09453401 |
62 | Muscle fiber atrophy (HP:0100295) | 2.08543139 |
63 | Pendular nystagmus (HP:0012043) | 2.08219231 |
64 | Trismus (HP:0000211) | 2.07613544 |
65 | Medulloblastoma (HP:0002885) | 2.07224163 |
66 | Hyperglycinemia (HP:0002154) | 2.04283202 |
67 | Hypoplasia of the pons (HP:0012110) | 2.04002327 |
68 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.01187481 |
69 | Horseshoe kidney (HP:0000085) | 2.00453609 |
70 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.00329586 |
71 | 11 pairs of ribs (HP:0000878) | 1.99440292 |
72 | Absent thumb (HP:0009777) | 1.98482342 |
73 | Atresia of the external auditory canal (HP:0000413) | 1.97905750 |
74 | Bifid tongue (HP:0010297) | 1.97417227 |
75 | Abnormality of the pons (HP:0007361) | 1.97414639 |
76 | Acute necrotizing encephalopathy (HP:0006965) | 1.97355158 |
77 | Macrocytic anemia (HP:0001972) | 1.97180777 |
78 | Cortical dysplasia (HP:0002539) | 1.96974356 |
79 | Premature ovarian failure (HP:0008209) | 1.96604263 |
80 | Cleft eyelid (HP:0000625) | 1.94994476 |
81 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.94661178 |
82 | Neoplasm of the adrenal cortex (HP:0100641) | 1.94500090 |
83 | Fibular aplasia (HP:0002990) | 1.93256589 |
84 | Increased serum lactate (HP:0002151) | 1.92486969 |
85 | Abnormality of alanine metabolism (HP:0010916) | 1.92466725 |
86 | Hyperalaninemia (HP:0003348) | 1.92466725 |
87 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.92466725 |
88 | Cellular immunodeficiency (HP:0005374) | 1.92300678 |
89 | Hepatocellular necrosis (HP:0001404) | 1.92186069 |
90 | Embryonal renal neoplasm (HP:0011794) | 1.91571382 |
91 | Short thumb (HP:0009778) | 1.90685011 |
92 | Optic nerve coloboma (HP:0000588) | 1.90099061 |
93 | Mitochondrial inheritance (HP:0001427) | 1.89949316 |
94 | Impulsivity (HP:0100710) | 1.89385613 |
95 | CNS hypomyelination (HP:0003429) | 1.89330253 |
96 | Glioma (HP:0009733) | 1.87611984 |
97 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.87456164 |
98 | Tracheoesophageal fistula (HP:0002575) | 1.86991752 |
99 | Abnormality of the duodenum (HP:0002246) | 1.86680251 |
100 | Pallor (HP:0000980) | 1.86636647 |
101 | Duplicated collecting system (HP:0000081) | 1.85797188 |
102 | Abnormality of DNA repair (HP:0003254) | 1.85751533 |
103 | Triphalangeal thumb (HP:0001199) | 1.85648696 |
104 | Spinal muscular atrophy (HP:0007269) | 1.84955157 |
105 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.83811580 |
106 | Poor head control (HP:0002421) | 1.83643538 |
107 | Progressive macrocephaly (HP:0004481) | 1.83159248 |
108 | Abnormal number of incisors (HP:0011064) | 1.83101887 |
109 | Abnormal protein glycosylation (HP:0012346) | 1.83077253 |
110 | Abnormal glycosylation (HP:0012345) | 1.83077253 |
111 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.83077253 |
112 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.83077253 |
113 | Microtia (HP:0008551) | 1.81857205 |
114 | Increased CSF lactate (HP:0002490) | 1.81680602 |
115 | Dandy-Walker malformation (HP:0001305) | 1.80667379 |
116 | Facial cleft (HP:0002006) | 1.80352590 |
117 | Neoplasm of the pancreas (HP:0002894) | 1.79944578 |
118 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.79760491 |
119 | Short 1st metacarpal (HP:0010034) | 1.79281306 |
120 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.79281306 |
121 | Breast aplasia (HP:0100783) | 1.78808502 |
122 | Adrenal hypoplasia (HP:0000835) | 1.78181629 |
123 | Pancreatic fibrosis (HP:0100732) | 1.77998075 |
124 | Capillary hemangiomas (HP:0005306) | 1.77746654 |
125 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.77491728 |
126 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.76808389 |
127 | Neoplasm of the adrenal gland (HP:0100631) | 1.76440458 |
128 | Prominent metopic ridge (HP:0005487) | 1.73928448 |
129 | Reduced antithrombin III activity (HP:0001976) | 1.73807605 |
130 | Lissencephaly (HP:0001339) | 1.72909451 |
131 | Absent epiphyses (HP:0010577) | 1.72809093 |
132 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.72809093 |
133 | Cerebral edema (HP:0002181) | 1.72164534 |
134 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.72073231 |
135 | Postnatal microcephaly (HP:0005484) | 1.71806203 |
136 | Agnosia (HP:0010524) | 1.71062414 |
137 | Neoplasm of the colon (HP:0100273) | 1.70143340 |
138 | Abnormality of the metopic suture (HP:0005556) | 1.70121780 |
139 | Progressive muscle weakness (HP:0003323) | 1.69307475 |
140 | Hepatic necrosis (HP:0002605) | 1.67338323 |
141 | Abnormality of serum amino acid levels (HP:0003112) | 1.65689254 |
142 | Lactic acidosis (HP:0003128) | 1.64233166 |
143 | Preaxial hand polydactyly (HP:0001177) | 1.63719074 |
144 | Astrocytoma (HP:0009592) | 1.63389540 |
145 | Abnormality of the astrocytes (HP:0100707) | 1.63389540 |
146 | Rhabdomyosarcoma (HP:0002859) | 1.62012481 |
147 | Hyperglycinuria (HP:0003108) | 1.60926773 |
148 | Cafe-au-lait spot (HP:0000957) | 1.60786518 |
149 | Molar tooth sign on MRI (HP:0002419) | 1.59358219 |
150 | Abnormality of midbrain morphology (HP:0002418) | 1.59358219 |
151 | Abnormality of the renal collecting system (HP:0004742) | 1.59301811 |
152 | Intestinal atresia (HP:0011100) | 1.58497388 |
153 | Abnormality of methionine metabolism (HP:0010901) | 1.58372025 |
154 | Pancytopenia (HP:0001876) | 1.58338289 |
155 | Abnormality of glycine metabolism (HP:0010895) | 1.57663772 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.02898606 |
2 | WEE1 | 3.67900882 |
3 | CDC7 | 3.20324203 |
4 | EIF2AK1 | 3.17267145 |
5 | PLK4 | 3.03703512 |
6 | SRPK1 | 2.95044139 |
7 | TRIM28 | 2.93407350 |
8 | STK16 | 2.87591656 |
9 | VRK1 | 2.76654918 |
10 | VRK2 | 2.66518787 |
11 | TTK | 2.25079016 |
12 | TSSK6 | 2.20101374 |
13 | MKNK1 | 2.16020798 |
14 | EIF2AK3 | 2.15877059 |
15 | ACVR1B | 2.11889812 |
16 | BRSK2 | 2.09983272 |
17 | PLK3 | 2.09527433 |
18 | PLK1 | 1.99727049 |
19 | NME2 | 1.72489715 |
20 | TAF1 | 1.71868034 |
21 | ZAK | 1.65313238 |
22 | TESK2 | 1.64900583 |
23 | NEK2 | 1.64639296 |
24 | DYRK2 | 1.59084398 |
25 | PIM2 | 1.57874929 |
26 | AURKB | 1.54759628 |
27 | DYRK3 | 1.54591467 |
28 | CDK7 | 1.50254900 |
29 | MKNK2 | 1.45007839 |
30 | CHEK2 | 1.43175209 |
31 | STK38L | 1.42995899 |
32 | CDK8 | 1.42748468 |
33 | PBK | 1.42465775 |
34 | ATR | 1.41342319 |
35 | CCNB1 | 1.40883158 |
36 | WNK3 | 1.39050368 |
37 | PASK | 1.33961438 |
38 | AURKA | 1.29429325 |
39 | NEK1 | 1.28965097 |
40 | BRSK1 | 1.26831908 |
41 | BCKDK | 1.13475361 |
42 | EPHA2 | 1.11684833 |
43 | EIF2AK2 | 1.10147708 |
44 | RPS6KB2 | 1.07113724 |
45 | STK10 | 1.06664953 |
46 | CHEK1 | 1.03307522 |
47 | NME1 | 1.02217626 |
48 | FRK | 1.01220011 |
49 | MST4 | 1.01046772 |
50 | STK4 | 0.98856223 |
51 | BRAF | 0.98622950 |
52 | TLK1 | 0.97194034 |
53 | RPS6KA4 | 0.93721030 |
54 | TNIK | 0.93334024 |
55 | TGFBR1 | 0.91560604 |
56 | LATS2 | 0.87623376 |
57 | MAP3K8 | 0.87619127 |
58 | MAP4K2 | 0.78765278 |
59 | MAP3K4 | 0.78554041 |
60 | CSNK1G2 | 0.77809385 |
61 | BMPR2 | 0.77700451 |
62 | IRAK4 | 0.77250165 |
63 | PAK4 | 0.77052830 |
64 | CSNK2A1 | 0.76953778 |
65 | CSNK1A1L | 0.76516135 |
66 | LIMK1 | 0.70860336 |
67 | ARAF | 0.70550489 |
68 | PIM1 | 0.69152604 |
69 | ATM | 0.68412178 |
70 | PINK1 | 0.68017588 |
71 | TXK | 0.66329650 |
72 | BCR | 0.66070295 |
73 | CDK2 | 0.65550100 |
74 | NEK6 | 0.65160581 |
75 | MELK | 0.64696242 |
76 | TESK1 | 0.64292724 |
77 | STK24 | 0.64015088 |
78 | CSNK2A2 | 0.63863123 |
79 | CLK1 | 0.62123760 |
80 | ALK | 0.61886187 |
81 | PRKCI | 0.61209217 |
82 | CDK4 | 0.60973398 |
83 | PAK1 | 0.60710365 |
84 | ERBB3 | 0.60657111 |
85 | MAP2K7 | 0.59213202 |
86 | ERBB4 | 0.57313377 |
87 | RPS6KA5 | 0.57029772 |
88 | MAP3K10 | 0.54002687 |
89 | CDK1 | 0.53595419 |
90 | KDR | 0.50052542 |
91 | INSRR | 0.46187818 |
92 | ABL2 | 0.46128843 |
93 | MAPK13 | 0.45636864 |
94 | STK3 | 0.44910569 |
95 | STK39 | 0.44253339 |
96 | ILK | 0.44200273 |
97 | MAP3K11 | 0.44171946 |
98 | CSNK1G3 | 0.43835984 |
99 | SIK3 | 0.43180408 |
100 | MOS | 0.43053569 |
101 | CDK12 | 0.41159737 |
102 | PRKDC | 0.40316685 |
103 | DAPK1 | 0.40270431 |
104 | GRK1 | 0.40001891 |
105 | BRD4 | 0.39071121 |
106 | FGFR1 | 0.38506676 |
107 | MAP4K1 | 0.36939851 |
108 | WNK4 | 0.34822907 |
109 | AKT2 | 0.34561826 |
110 | YES1 | 0.34167763 |
111 | CDK6 | 0.34131718 |
112 | TAOK2 | 0.34075493 |
113 | SMG1 | 0.33936492 |
114 | SCYL2 | 0.33343454 |
115 | MAP3K6 | 0.33037349 |
116 | PNCK | 0.32075352 |
117 | CHUK | 0.31389861 |
118 | CSNK1D | 0.30196029 |
119 | RAF1 | 0.29676191 |
120 | CDK9 | 0.29563849 |
121 | CDK18 | 0.29035341 |
122 | CDK14 | 0.28715837 |
123 | CSNK1G1 | 0.27623493 |
124 | BMPR1B | 0.27620321 |
125 | NUAK1 | 0.25328583 |
126 | KSR1 | 0.24354361 |
127 | MINK1 | 0.24326300 |
128 | MAPKAPK5 | 0.24306226 |
129 | PLK2 | 0.23003936 |
130 | CDK3 | 0.22030823 |
131 | RPS6KB1 | 0.21445776 |
132 | CSNK1E | 0.21034453 |
133 | LATS1 | 0.19218154 |
134 | MAPKAPK2 | 0.17128907 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.44607936 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.16937324 |
3 | * RNA polymerase_Homo sapiens_hsa03020 | 4.02455451 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 3.78173219 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.66292314 |
6 | Spliceosome_Homo sapiens_hsa03040 | 3.40702058 |
7 | Ribosome_Homo sapiens_hsa03010 | 3.40059042 |
8 | RNA transport_Homo sapiens_hsa03013 | 2.99954835 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.97178726 |
10 | Base excision repair_Homo sapiens_hsa03410 | 2.96801348 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.84130279 |
12 | * Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.69337978 |
13 | Cell cycle_Homo sapiens_hsa04110 | 2.66647444 |
14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.59920757 |
15 | RNA degradation_Homo sapiens_hsa03018 | 2.24692888 |
16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.23399136 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.16505398 |
18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.84356071 |
19 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.63372481 |
20 | * Purine metabolism_Homo sapiens_hsa00230 | 1.63132464 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.60885638 |
22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.58821208 |
23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.47997037 |
24 | Protein export_Homo sapiens_hsa03060 | 1.45603944 |
25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41675407 |
26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.36289576 |
27 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.34835594 |
28 | Parkinsons disease_Homo sapiens_hsa05012 | 1.31711416 |
29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.31697695 |
30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.30708704 |
31 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.30526045 |
32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.27870046 |
33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.25664105 |
34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.19590094 |
35 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.17523615 |
36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14908328 |
37 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.00805435 |
38 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.00128229 |
39 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.98801186 |
40 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.91321288 |
41 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.87943518 |
42 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75342065 |
43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.74894236 |
44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.73517726 |
45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.73034882 |
46 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.71934268 |
47 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.70130185 |
48 | Lysine degradation_Homo sapiens_hsa00310 | 0.69850866 |
49 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.68786890 |
50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65838785 |
51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65542279 |
52 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.65530378 |
53 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.61727759 |
54 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.61657775 |
55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61147988 |
56 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.57228910 |
57 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.56532975 |
58 | HTLV-I infection_Homo sapiens_hsa05166 | 0.55813013 |
59 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.54220219 |
60 | Alzheimers disease_Homo sapiens_hsa05010 | 0.53811592 |
61 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51388524 |
62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50930716 |
63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48860789 |
64 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.48087167 |
65 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.46159419 |
66 | Phototransduction_Homo sapiens_hsa04744 | 0.45638169 |
67 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.45180855 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.44145507 |
69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43205895 |
70 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.40929197 |
71 | Legionellosis_Homo sapiens_hsa05134 | 0.39522705 |
72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.39130067 |
73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38536736 |
74 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38066166 |
75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37843842 |
76 | Thyroid cancer_Homo sapiens_hsa05216 | 0.36853852 |
77 | Peroxisome_Homo sapiens_hsa04146 | 0.36041856 |
78 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.34461310 |
79 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.34120824 |
80 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.33899947 |
81 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.33637594 |
82 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.33556703 |
83 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.32910138 |
84 | Shigellosis_Homo sapiens_hsa05131 | 0.32311432 |
85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.31160973 |
86 | Sulfur relay system_Homo sapiens_hsa04122 | 0.30777746 |
87 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30578184 |
88 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.29518500 |
89 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.29334542 |
90 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.28121661 |
91 | Other glycan degradation_Homo sapiens_hsa00511 | 0.27920397 |
92 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.26699031 |
93 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.24904205 |
94 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.24899702 |
95 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24431666 |
96 | Colorectal cancer_Homo sapiens_hsa05210 | 0.24129559 |
97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.23688952 |
98 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.22570288 |
99 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.22183499 |
100 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.21955560 |
101 | Asthma_Homo sapiens_hsa05310 | 0.21554023 |
102 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.21262474 |
103 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20658801 |
104 | Apoptosis_Homo sapiens_hsa04210 | 0.19484334 |
105 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.19290602 |
106 | Carbon metabolism_Homo sapiens_hsa01200 | 0.19069864 |
107 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.18789555 |
108 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.18649819 |
109 | Measles_Homo sapiens_hsa05162 | 0.18444505 |
110 | Alcoholism_Homo sapiens_hsa05034 | 0.16607622 |
111 | Galactose metabolism_Homo sapiens_hsa00052 | 0.16304083 |
112 | Allograft rejection_Homo sapiens_hsa05330 | 0.16283358 |
113 | Tight junction_Homo sapiens_hsa04530 | 0.14740546 |
114 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.14574130 |
115 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.14439570 |
116 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.13811816 |
117 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.13533092 |
118 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.13274548 |
119 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.12933250 |
120 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.12916972 |
121 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.12093461 |
122 | Pathways in cancer_Homo sapiens_hsa05200 | 0.11773696 |
123 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.11507354 |
124 | Melanoma_Homo sapiens_hsa05218 | 0.11079471 |
125 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.10150234 |
126 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.10086720 |
127 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.09913115 |
128 | Influenza A_Homo sapiens_hsa05164 | 0.09315749 |
129 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.08626807 |
130 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.08426473 |
131 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.08413097 |