POLR2J

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)5.79371177
2viral transcription (GO:0019083)5.62853424
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.53965610
4ribosomal small subunit assembly (GO:0000028)5.46977623
5translational termination (GO:0006415)5.46890841
6ATP synthesis coupled proton transport (GO:0015986)5.21865285
7energy coupled proton transport, down electrochemical gradient (GO:0015985)5.21865285
8proteasome assembly (GO:0043248)5.09759206
9maturation of SSU-rRNA (GO:0030490)4.99349966
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.89201756
11cotranslational protein targeting to membrane (GO:0006613)4.87644239
12protein targeting to ER (GO:0045047)4.81243979
13termination of RNA polymerase III transcription (GO:0006386)4.74709233
14transcription elongation from RNA polymerase III promoter (GO:0006385)4.74709233
15translational elongation (GO:0006414)4.71322812
16DNA deamination (GO:0045006)4.63157838
17establishment of protein localization to endoplasmic reticulum (GO:0072599)4.58229412
18protein localization to endoplasmic reticulum (GO:0070972)4.58121739
19chaperone-mediated protein transport (GO:0072321)4.43429905
20translational initiation (GO:0006413)4.42381463
21ribosomal large subunit biogenesis (GO:0042273)4.42248016
22cellular protein complex disassembly (GO:0043624)4.38921186
23viral life cycle (GO:0019058)4.33376417
24mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.32331457
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.22881376
26cytochrome complex assembly (GO:0017004)4.15098935
27establishment of protein localization to mitochondrial membrane (GO:0090151)4.07557484
28pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.07470867
29translation (GO:0006412)4.06301065
30negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.05782085
31establishment of integrated proviral latency (GO:0075713)4.05757090
32rRNA modification (GO:0000154)3.99579299
33protein neddylation (GO:0045116)3.98646871
34ribonucleoprotein complex biogenesis (GO:0022613)3.97366336
35* 7-methylguanosine mRNA capping (GO:0006370)3.95478908
36protein localization to mitochondrion (GO:0070585)3.94167383
37* RNA capping (GO:0036260)3.92928968
38* 7-methylguanosine RNA capping (GO:0009452)3.92928968
39respiratory electron transport chain (GO:0022904)3.85502162
40positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.83690929
41spliceosomal snRNP assembly (GO:0000387)3.81137745
42protein complex disassembly (GO:0043241)3.78964974
43anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.78089894
44regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.77211742
45negative regulation of ligase activity (GO:0051352)3.76613100
46negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.76613100
47electron transport chain (GO:0022900)3.74854855
48rRNA processing (GO:0006364)3.74098822
49tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.73637328
50RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.73637328
51ATP biosynthetic process (GO:0006754)3.72078291
52telomere maintenance via semi-conservative replication (GO:0032201)3.69874525
53CENP-A containing nucleosome assembly (GO:0034080)3.69711357
54base-excision repair, AP site formation (GO:0006285)3.68693468
55purine nucleoside triphosphate biosynthetic process (GO:0009145)3.67193969
56purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.66141173
57oxidative phosphorylation (GO:0006119)3.64623313
58transcription elongation from RNA polymerase I promoter (GO:0006362)3.61851136
59macromolecular complex disassembly (GO:0032984)3.61278191
60cellular component biogenesis (GO:0044085)3.60921613
61regulation of cellular amino acid metabolic process (GO:0006521)3.60747370
62spliceosomal complex assembly (GO:0000245)3.60256659
63rRNA metabolic process (GO:0016072)3.59655850
64DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.59629882
65DNA strand elongation involved in DNA replication (GO:0006271)3.59610881
66mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.59087294
67mitochondrial respiratory chain complex I assembly (GO:0032981)3.59087294
68NADH dehydrogenase complex assembly (GO:0010257)3.59087294
69GTP biosynthetic process (GO:0006183)3.56163345
70chromatin remodeling at centromere (GO:0031055)3.55315607
71deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.54735606
72signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.54218941
73intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.54218941
74pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.53812824
75signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.53542690
76signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.53542690
77signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.53542690
78nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.49783621
79exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.49346574
80protein complex biogenesis (GO:0070271)3.47639057
81protein deneddylation (GO:0000338)3.46425557
82signal transduction involved in DNA damage checkpoint (GO:0072422)3.45649041
83signal transduction involved in DNA integrity checkpoint (GO:0072401)3.45649041
84termination of RNA polymerase I transcription (GO:0006363)3.45241770
85L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.44631480
86transcription from RNA polymerase I promoter (GO:0006360)3.44431029
87cullin deneddylation (GO:0010388)3.44357255
88protein targeting to mitochondrion (GO:0006626)3.44260866
89hydrogen ion transmembrane transport (GO:1902600)3.43817004
90deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.43793478
91DNA replication initiation (GO:0006270)3.43181741
92signal transduction involved in cell cycle checkpoint (GO:0072395)3.42549986
93formation of translation preinitiation complex (GO:0001731)3.41519931
94DNA strand elongation (GO:0022616)3.40972912
95* transcription-coupled nucleotide-excision repair (GO:0006283)3.38549102
96mitochondrial transport (GO:0006839)3.37539207
97ribonucleoside triphosphate biosynthetic process (GO:0009201)3.37452256
98establishment of protein localization to mitochondrion (GO:0072655)3.37393415
99regulation of mitochondrial translation (GO:0070129)3.36924412
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.34773056
101establishment of viral latency (GO:0019043)3.34123035
102telomere maintenance via recombination (GO:0000722)3.33770177
103DNA replication checkpoint (GO:0000076)3.31227658
104guanosine-containing compound biosynthetic process (GO:1901070)3.31032598
105deoxyribonucleotide catabolic process (GO:0009264)3.30179162
106antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.27899448
107nuclear-transcribed mRNA catabolic process (GO:0000956)3.27882511
108pseudouridine synthesis (GO:0001522)3.26640552
109metallo-sulfur cluster assembly (GO:0031163)3.24080718
110iron-sulfur cluster assembly (GO:0016226)3.24080718
111positive regulation of ligase activity (GO:0051351)3.23933975
112mitochondrial respiratory chain complex assembly (GO:0033108)3.23681180
113UTP biosynthetic process (GO:0006228)3.23344837
114purine nucleobase biosynthetic process (GO:0009113)3.21478374
115kinetochore assembly (GO:0051382)3.19835580
116pyrimidine nucleotide catabolic process (GO:0006244)3.19431495
117rRNA methylation (GO:0031167)3.17193495
118inner mitochondrial membrane organization (GO:0007007)3.16285479
119protein-cofactor linkage (GO:0018065)3.15963843
120mitotic metaphase plate congression (GO:0007080)3.15526049
121respiratory chain complex IV assembly (GO:0008535)3.15395262
122regulation of ubiquitin-protein transferase activity (GO:0051438)3.14766984
123deoxyribose phosphate catabolic process (GO:0046386)3.13044872
124nucleoside triphosphate biosynthetic process (GO:0009142)3.12407978
125protein targeting to membrane (GO:0006612)3.11990421
126pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.08100706
127pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.08081608
128deoxyribose phosphate biosynthetic process (GO:0046385)3.07462160

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.79816975
2* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.77528610
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.46322277
4MYC_18555785_ChIP-Seq_MESCs_Mouse4.34335923
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.23016344
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.21284010
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.99327613
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.79300606
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.69317101
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.57090055
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.51843295
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.36810313
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.33740049
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.17839345
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.17021813
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.08266484
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.06561376
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.91815947
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.82101010
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.81141405
21* VDR_23849224_ChIP-Seq_CD4+_Human2.73586172
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.60587437
23XRN2_22483619_ChIP-Seq_HELA_Human2.53639152
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.45698668
25DCP1A_22483619_ChIP-Seq_HELA_Human2.35306666
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.30227081
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.24507256
28SRF_21415370_ChIP-Seq_HL-1_Mouse2.24263745
29FOXP3_21729870_ChIP-Seq_TREG_Human2.19420891
30ELK1_19687146_ChIP-ChIP_HELA_Human2.18650644
31TTF2_22483619_ChIP-Seq_HELA_Human2.16545684
32YY1_21170310_ChIP-Seq_MESCs_Mouse2.16164135
33* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13752610
34GABP_19822575_ChIP-Seq_HepG2_Human2.07285893
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.05227975
36* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.91223143
37FOXM1_23109430_ChIP-Seq_U2OS_Human1.90703103
38CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.86340101
39* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82526147
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.75348498
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.72739785
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.71948837
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.70736618
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.69583156
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.65415155
46CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.65197053
47ELK1_22589737_ChIP-Seq_MCF10A_Human1.61051824
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59946070
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57146708
50CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.56953127
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53381513
52* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49252743
53HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49140866
54MYC_18940864_ChIP-ChIP_HL60_Human1.45634539
55FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43638534
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38840577
57POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.36549408
58AR_21909140_ChIP-Seq_LNCAP_Human1.36193429
59PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.33270465
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.31692552
61* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29957708
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.26827298
63ZFX_18555785_ChIP-Seq_MESCs_Mouse1.25686162
64* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.24756647
65CIITA_25753668_ChIP-Seq_RAJI_Human1.22537774
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19168614
67E2F1_21310950_ChIP-Seq_MCF-7_Human1.18059223
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16888392
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.15783690
70KDM5A_27292631_Chip-Seq_BREAST_Human1.13073322
71CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11957557
72* FOXP1_21924763_ChIP-Seq_HESCs_Human1.11067868
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09219555
74IRF1_19129219_ChIP-ChIP_H3396_Human1.09150556
75HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.00950013
76TET1_21451524_ChIP-Seq_MESCs_Mouse0.99766232
77CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96330227
78CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96218685
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.94725998
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92608927
81* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90331539
82CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.89778096
83* CTCF_26484167_Chip-Seq_Bcells_Mouse0.89333213
84* SOX2_18555785_ChIP-Seq_MESCs_Mouse0.89141784
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87161726
86SOX17_20123909_ChIP-Seq_XEN_Mouse0.87143523
87BCL6_27268052_Chip-Seq_Bcells_Human0.84397451
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83740997
89* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.83571932
90ELF1_20517297_ChIP-Seq_JURKAT_Human0.83168140
91KAP1_22055183_ChIP-Seq_ESCs_Mouse0.82405405
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81888138
93NOTCH1_21737748_ChIP-Seq_TLL_Human0.81365411
94RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.80974957
95STAT3_1855785_ChIP-Seq_MESCs_Mouse0.80757046
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.79849055
97PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.78485656
98POU5F1_16153702_ChIP-ChIP_HESCs_Human0.76227373
99SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.76010161
100ZNF263_19887448_ChIP-Seq_K562_Human0.74600537
101* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.73766091
102TP63_19390658_ChIP-ChIP_HaCaT_Human0.73517848
103KLF4_18555785_ChIP-Seq_MESCs_Mouse0.73212802
104DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.71902582
105SOX2_16153702_ChIP-ChIP_HESCs_Human0.71665909
106BP1_19119308_ChIP-ChIP_Hs578T_Human0.71514613
107SPI1_23547873_ChIP-Seq_NB4_Human0.71450709
108YY1_22570637_ChIP-Seq_MALME-3M_Human0.70153766
109* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.68854954
110* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.67785888
111EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.66926898
112* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.66154658
113TFEB_21752829_ChIP-Seq_HELA_Human0.66133100
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.64642361
115STAT1_20625510_ChIP-Seq_HELA_Human0.63374489
116NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.62201624
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.61055137
118RBPJ_22232070_ChIP-Seq_NCS_Mouse0.60979739

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.89689696
2MP0004957_abnormal_blastocyst_morpholog3.92603563
3MP0009379_abnormal_foot_pigmentation3.49971195
4MP0010094_abnormal_chromosome_stability3.48953955
5MP0003111_abnormal_nucleus_morphology3.29815981
6MP0003718_maternal_effect3.26836305
7MP0003077_abnormal_cell_cycle3.25978723
8MP0008057_abnormal_DNA_replication3.06120610
9MP0001529_abnormal_vocalization3.01737031
10MP0008058_abnormal_DNA_repair2.94277412
11MP0008932_abnormal_embryonic_tissue2.89417390
12MP0008877_abnormal_DNA_methylation2.47109549
13MP0003786_premature_aging2.44186915
14MP0003136_yellow_coat_color2.33886959
15MP0008007_abnormal_cellular_replicative2.27311691
16MP0002102_abnormal_ear_morphology2.13654861
17MP0002837_dystrophic_cardiac_calcinosis2.13354796
18MP0001905_abnormal_dopamine_level2.04610676
19MP0006292_abnormal_olfactory_placode2.02767450
20MP0003315_abnormal_perineum_morphology1.95860034
21MP0005451_abnormal_body_composition1.94026126
22MP0002163_abnormal_gland_morphology1.85919538
23MP0001764_abnormal_homeostasis1.83092818
24MP0002653_abnormal_ependyma_morphology1.82711451
25MP0006036_abnormal_mitochondrial_physio1.75567463
26MP0003011_delayed_dark_adaptation1.72813166
27MP0005408_hypopigmentation1.64328912
28MP0009333_abnormal_splenocyte_physiolog1.63486980
29MP0002132_abnormal_respiratory_system1.61486838
30MP0003186_abnormal_redox_activity1.59335608
31MP0006035_abnormal_mitochondrial_morpho1.57063260
32MP0008875_abnormal_xenobiotic_pharmacok1.54781621
33MP0005084_abnormal_gallbladder_morpholo1.52763053
34MP0001986_abnormal_taste_sensitivity1.47216635
35MP0000566_synostosis1.46421374
36MP0003880_abnormal_central_pattern1.45934421
37MP0003123_paternal_imprinting1.45878346
38MP0004147_increased_porphyrin_level1.45767724
39MP0001730_embryonic_growth_arrest1.43294311
40MP0000372_irregular_coat_pigmentation1.35746319
41MP0008260_abnormal_autophagy1.34812096
42MP0003195_calcinosis1.33839045
43MP0008995_early_reproductive_senescence1.31657257
44MP0002638_abnormal_pupillary_reflex1.29232576
45MP0000490_abnormal_crypts_of1.29088583
46MP0000350_abnormal_cell_proliferation1.27892643
47MP0001485_abnormal_pinna_reflex1.23347016
48MP0002938_white_spotting1.22750600
49MP0002210_abnormal_sex_determination1.22686804
50MP0001727_abnormal_embryo_implantation1.22677152
51MP0008789_abnormal_olfactory_epithelium1.22589994
52MP0001293_anophthalmia1.21908322
53MP0004381_abnormal_hair_follicle1.21598118
54MP0004142_abnormal_muscle_tone1.13984351
55MP0003950_abnormal_plasma_membrane1.12368241
56MP0005636_abnormal_mineral_homeostasis1.09378771
57MP0002277_abnormal_respiratory_mucosa1.08877775
58MP0000313_abnormal_cell_death1.08406749
59MP0002396_abnormal_hematopoietic_system1.08060697
60MP0005646_abnormal_pituitary_gland1.07451280
61MP0003938_abnormal_ear_development1.07389803
62MP0001968_abnormal_touch/_nociception1.06709986
63MP0000749_muscle_degeneration1.06389679
64MP0005379_endocrine/exocrine_gland_phen1.06202714
65MP0001929_abnormal_gametogenesis1.02813010
66MP0005410_abnormal_fertilization1.00225242
67MP0003806_abnormal_nucleotide_metabolis0.99641190
68MP0000653_abnormal_sex_gland0.98501754
69MP0002160_abnormal_reproductive_system0.98432720
70MP0001145_abnormal_male_reproductive0.96966733
71MP0000631_abnormal_neuroendocrine_gland0.96119740
72MP0003763_abnormal_thymus_physiology0.92287322
73MP0004145_abnormal_muscle_electrophysio0.91497721
74MP0001853_heart_inflammation0.90085662
75MP0003646_muscle_fatigue0.87815706
76MP0001697_abnormal_embryo_size0.87285825
77MP0005075_abnormal_melanosome_morpholog0.87158179
78MP0002019_abnormal_tumor_incidence0.87018999
79MP0005389_reproductive_system_phenotype0.86937141
80MP0005332_abnormal_amino_acid0.86679990
81MP0008872_abnormal_physiological_respon0.86111979
82MP0002095_abnormal_skin_pigmentation0.85915819
83MP0002234_abnormal_pharynx_morphology0.85842749
84MP0002751_abnormal_autonomic_nervous0.85659739
85MP0004019_abnormal_vitamin_homeostasis0.85003827
86MP0004133_heterotaxia0.84357983
87MP0000358_abnormal_cell_content/0.81315654
88MP0006276_abnormal_autonomic_nervous0.80547843
89MP0001881_abnormal_mammary_gland0.80178995
90MP0005551_abnormal_eye_electrophysiolog0.79892938
91MP0002080_prenatal_lethality0.79891206
92MP0000750_abnormal_muscle_regeneration0.79654555
93MP0003567_abnormal_fetal_cardiomyocyte0.78104950
94MP0003121_genomic_imprinting0.77971170
95MP0003656_abnormal_erythrocyte_physiolo0.77290890
96MP0005395_other_phenotype0.76739008
97MP0001119_abnormal_female_reproductive0.75777666
98MP0006072_abnormal_retinal_apoptosis0.75741841
99MP0003937_abnormal_limbs/digits/tail_de0.75192583
100MP0005319_abnormal_enzyme/_coenzyme0.74096944
101MP0002085_abnormal_embryonic_tissue0.72629701
102MP0003137_abnormal_impulse_conducting0.72622760
103MP0005253_abnormal_eye_physiology0.72451961
104MP0005409_darkened_coat_color0.71211470
105MP0003941_abnormal_skin_development0.68327714
106MP0001542_abnormal_bone_strength0.67770885
107MP0000015_abnormal_ear_pigmentation0.65535499
108MP0002139_abnormal_hepatobiliary_system0.65104883
109MP0002138_abnormal_hepatobiliary_system0.64805766
110MP0005083_abnormal_biliary_tract0.64728942
111MP0005670_abnormal_white_adipose0.64418047
112MP0002090_abnormal_vision0.64233908
113MP0001188_hyperpigmentation0.63763191
114MP0001672_abnormal_embryogenesis/_devel0.62673979
115MP0005380_embryogenesis_phenotype0.62673979
116MP0002876_abnormal_thyroid_physiology0.62103209
117MP0005499_abnormal_olfactory_system0.62093124
118MP0005394_taste/olfaction_phenotype0.62093124
119MP0000703_abnormal_thymus_morphology0.61954248
120MP0009046_muscle_twitch0.61546856
121MP0003221_abnormal_cardiomyocyte_apopto0.60896280
122MP0000462_abnormal_digestive_system0.60558901
123MP0005330_cardiomyopathy0.60501329
124MP0008873_increased_physiological_sensi0.60257172
125MP0000678_abnormal_parathyroid_gland0.59613226
126MP0000049_abnormal_middle_ear0.59548083
127MP0003698_abnormal_male_reproductive0.59334882
128MP0002722_abnormal_immune_system0.58983024
129MP0002398_abnormal_bone_marrow0.58640395
130MP0000343_altered_response_to0.58635660
131MP0000689_abnormal_spleen_morphology0.58592898
132MP0001919_abnormal_reproductive_system0.57564377
133MP0005423_abnormal_somatic_nervous0.57330772
134MP0005171_absent_coat_pigmentation0.55986744
135MP0009697_abnormal_copulation0.55389609
136MP0010030_abnormal_orbit_morphology0.52834088
137MP0002736_abnormal_nociception_after0.51963349

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.66931175
2Acute necrotizing encephalopathy (HP:0006965)5.45276021
3Abnormal number of erythroid precursors (HP:0012131)5.25240396
4Mitochondrial inheritance (HP:0001427)4.94020601
5Abnormal mitochondria in muscle tissue (HP:0008316)4.83240200
6Reticulocytopenia (HP:0001896)4.78607055
7Hepatocellular necrosis (HP:0001404)4.42059402
8Progressive macrocephaly (HP:0004481)4.39594481
9Acute encephalopathy (HP:0006846)4.30965658
10Increased hepatocellular lipid droplets (HP:0006565)4.27243837
11Increased CSF lactate (HP:0002490)4.24911722
12Cerebral hypomyelination (HP:0006808)3.93212028
13Macrocytic anemia (HP:0001972)3.88569417
143-Methylglutaconic aciduria (HP:0003535)3.88300789
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.86349231
16Birth length less than 3rd percentile (HP:0003561)3.84367502
17Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.80536827
18Decreased activity of mitochondrial respiratory chain (HP:0008972)3.80536827
19Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.75166723
20Hepatic necrosis (HP:0002605)3.73267686
21Breast hypoplasia (HP:0003187)3.68349027
22Lipid accumulation in hepatocytes (HP:0006561)3.67180576
23Renal Fanconi syndrome (HP:0001994)3.63516855
24Pallor (HP:0000980)3.40958387
25Abnormality of glycolysis (HP:0004366)3.34647875
26Increased serum pyruvate (HP:0003542)3.34647875
27Increased serum lactate (HP:0002151)3.24609242
28Exertional dyspnea (HP:0002875)3.23667557
29Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.20035239
30Respiratory failure (HP:0002878)2.98772244
31Aplastic anemia (HP:0001915)2.96419110
32Methylmalonic aciduria (HP:0012120)2.94938452
33Exercise intolerance (HP:0003546)2.94645195
34Increased intramyocellular lipid droplets (HP:0012240)2.92480243
35Leukodystrophy (HP:0002415)2.91639432
36Oral leukoplakia (HP:0002745)2.90463966
37Rough bone trabeculation (HP:0100670)2.88873113
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.78900579
39Lactic acidosis (HP:0003128)2.76155539
40Carpal bone hypoplasia (HP:0001498)2.73215377
41Cerebral edema (HP:0002181)2.71363113
42Respiratory difficulties (HP:0002880)2.70977516
43Parakeratosis (HP:0001036)2.65972220
44Lethargy (HP:0001254)2.64995065
45Optic disc pallor (HP:0000543)2.61878126
46Methylmalonic acidemia (HP:0002912)2.55311845
47Patellar aplasia (HP:0006443)2.46813316
48CNS hypomyelination (HP:0003429)2.42395144
49Secondary amenorrhea (HP:0000869)2.38806066
50Aplasia/Hypoplasia of the patella (HP:0006498)2.35207606
51Chromsome breakage (HP:0040012)2.32670047
52Aplasia/hypoplasia of the uterus (HP:0008684)2.32620216
53Dicarboxylic aciduria (HP:0003215)2.32427517
54Abnormality of dicarboxylic acid metabolism (HP:0010995)2.32427517
55Abnormality of the preputium (HP:0100587)2.30457233
56Increased muscle lipid content (HP:0009058)2.29622358
57Abnormal protein glycosylation (HP:0012346)2.27438409
58Abnormal glycosylation (HP:0012345)2.27438409
59Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27438409
60Abnormal protein N-linked glycosylation (HP:0012347)2.27438409
61Abnormal trabecular bone morphology (HP:0100671)2.25298634
62CNS demyelination (HP:0007305)2.22879454
63Congenital ichthyosiform erythroderma (HP:0007431)2.19820963
64X-linked dominant inheritance (HP:0001423)2.19191213
65Type I transferrin isoform profile (HP:0003642)2.19024336
66Abnormality of the heme biosynthetic pathway (HP:0010472)2.17691834
67Chromosomal breakage induced by crosslinking agents (HP:0003221)2.17511223
68Abnormality of renal resorption (HP:0011038)2.16669950
69Amniotic constriction ring (HP:0009775)2.14098739
70Abnormality of placental membranes (HP:0011409)2.14098739
71Generalized aminoaciduria (HP:0002909)2.13511258
72Abnormality of the anterior horn cell (HP:0006802)2.12697789
73Degeneration of anterior horn cells (HP:0002398)2.12697789
74Meckel diverticulum (HP:0002245)2.10751749
75Hyperphosphaturia (HP:0003109)2.08405506
76Hyperglycinemia (HP:0002154)2.08016464
77Microvesicular hepatic steatosis (HP:0001414)2.07288474
78Triphalangeal thumb (HP:0001199)2.06685596
79Severe visual impairment (HP:0001141)2.06292442
80Duplicated collecting system (HP:0000081)2.06151933
81Microretrognathia (HP:0000308)2.04108473
82Absent radius (HP:0003974)2.03716307
83Multiple enchondromatosis (HP:0005701)2.03567938
84Absent thumb (HP:0009777)2.02713824
85Emotional lability (HP:0000712)2.00509438
86Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.00138689
87Premature graying of hair (HP:0002216)1.99960971
88Abnormality of the ileum (HP:0001549)1.99637461
89Reduced antithrombin III activity (HP:0001976)1.96588681
90Delusions (HP:0000746)1.95524661
91Abnormality of alanine metabolism (HP:0010916)1.94865646
92Hyperalaninemia (HP:0003348)1.94865646
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.94865646
94Adrenal hypoplasia (HP:0000835)1.93829490
95Pancreatic cysts (HP:0001737)1.93302072
96Abnormality of midbrain morphology (HP:0002418)1.92565613
97Molar tooth sign on MRI (HP:0002419)1.92565613
98Congenital, generalized hypertrichosis (HP:0004540)1.92333266
99Horseshoe kidney (HP:0000085)1.91905082
100Aplasia involving forearm bones (HP:0009822)1.90250576
101Absent forearm bone (HP:0003953)1.90250576
102Stenosis of the external auditory canal (HP:0000402)1.90248515
103Cleft eyelid (HP:0000625)1.87802514
104Absent rod-and cone-mediated responses on ERG (HP:0007688)1.87411723
105Pancytopenia (HP:0001876)1.85628055
106Sclerocornea (HP:0000647)1.83055445
107Aplasia/Hypoplasia involving the musculature (HP:0001460)1.82203055
108Premature ovarian failure (HP:0008209)1.81286331
109Bone marrow hypocellularity (HP:0005528)1.80986582
110Abnormality of aromatic amino acid family metabolism (HP:0004338)1.80601382
111True hermaphroditism (HP:0010459)1.80531959
112Progressive microcephaly (HP:0000253)1.80400211
113Abnormality of chromosome stability (HP:0003220)1.80245507
114Testicular atrophy (HP:0000029)1.80212446
115Type 2 muscle fiber atrophy (HP:0003554)1.79538399
116Muscle fiber atrophy (HP:0100295)1.79289782
117Trismus (HP:0000211)1.78856490
118Abnormality of the renal collecting system (HP:0004742)1.78379744
119Sparse eyelashes (HP:0000653)1.76670368
120Hypoplasia of the uterus (HP:0000013)1.75485179
121Cellular immunodeficiency (HP:0005374)1.73993924
122Abnormality of magnesium homeostasis (HP:0004921)1.73179145
123Pancreatic fibrosis (HP:0100732)1.69745672
124Abnormal lung lobation (HP:0002101)1.68207339
125Unsteady gait (HP:0002317)1.67811607
126Medial flaring of the eyebrow (HP:0010747)1.67683144
127Cholecystitis (HP:0001082)1.67509779
128Abnormal gallbladder physiology (HP:0012438)1.67509779
129Abnormality of urine glucose concentration (HP:0011016)1.67344906
130Glycosuria (HP:0003076)1.67344906
131Hypoplasia of the capital femoral epiphysis (HP:0003090)1.66018739
132Blindness (HP:0000618)1.65681542
133Nausea (HP:0002018)1.64136072
134Abnormal rod and cone electroretinograms (HP:0008323)1.63448523
135Vomiting (HP:0002013)1.62462262
136Opisthotonus (HP:0002179)1.62347778
137Poor suck (HP:0002033)1.60728683
138Abnormality of the labia minora (HP:0012880)1.59564473
139Abnormal urine phosphate concentration (HP:0012599)1.58558445
140Progressive muscle weakness (HP:0003323)1.58237015

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.26734020
2BUB14.75511333
3STK163.82729561
4NME23.65290577
5WEE13.33290706
6EIF2AK13.23449937
7SRPK12.78003191
8VRK12.77473867
9NME12.67248104
10PLK42.49634829
11CDC72.18581866
12TESK22.14195224
13EIF2AK32.03816965
14TLK11.86014453
15DYRK21.78608422
16DYRK31.74419046
17NEK11.67410108
18PBK1.66559131
19ACVR1B1.61092074
20MKNK11.59270617
21PIM21.58020457
22MST41.53392571
23PNCK1.47693703
24PLK11.47027573
25PDK21.46153798
26ARAF1.44401591
27NUAK11.34581777
28TSSK61.31609969
29AURKA1.31480374
30BRAF1.30915993
31BRSK21.30583407
32MAP4K21.30096979
33TTK1.28260009
34TRIM281.28029377
35CDK191.27476703
36BCR1.26262325
37AURKB1.24112317
38LIMK11.23147185
39BMPR1B1.21784352
40PLK31.21624403
41ZAK1.20852884
42CDK81.20138863
43STK391.17754488
44MAP3K121.11807492
45LRRK21.11120526
46CDK71.08418317
47ABL21.07421709
48CCNB11.04379161
49BMPR21.00749066
50MKNK20.99769763
51WNK30.95893506
52OXSR10.95350118
53MUSK0.95203122
54CHEK20.94307834
55EIF2AK20.93622997
56RPS6KA50.87685802
57CSNK1G30.85331241
58PHKG10.85307620
59PHKG20.85307620
60MAPKAPK50.84129025
61CLK10.82728328
62DAPK10.82286519
63TAOK20.80862077
64NEK20.79361048
65CSNK2A10.78610157
66MAPKAPK30.76992630
67IRAK30.76557093
68PAK10.76209630
69CSNK1G20.76163307
70ATR0.75595261
71MAP3K110.74307141
72RPS6KB20.72533764
73ILK0.72071925
74IRAK40.71568389
75CSNK2A20.71397705
76MYLK0.69866993
77BRSK10.68172305
78DAPK30.67086714
79MAP2K70.66045593
80PRKCI0.63284851
81KDR0.62059573
82GRK10.58756273
83CASK0.58752760
84CSNK1G10.56033737
85CHEK10.53791434
86STK40.52869103
87PASK0.51762978
88TNIK0.51715553
89INSRR0.51138732
90ADRBK20.48968218
91CDK30.48946461
92GRK70.47365555
93MAPK130.46752456
94PKN10.45510342
95UHMK10.43911893
96CAMK2G0.43887521
97MARK30.43817048
98MAP3K80.43698349
99CAMK2B0.43607010
100AKT20.43427951
101TNK20.43333501
102BCKDK0.40269971
103PINK10.40256889
104CDK11A0.37311858
105STK38L0.37090209
106RPS6KA40.36780507
107CAMK2D0.36618660
108TAF10.35822673
109TESK10.35578560
110MARK10.35521996
111TEC0.34994435
112NEK60.34692751
113ATM0.34611883
114TXK0.34307923
115OBSCN0.33731419
116CDK180.33083195
117CDK10.32802564
118CDK150.32456710
119CDK20.32274827
120PAK40.32006438
121RAF10.30601414
122GRK60.29959964
123PIM10.29557946
124CDK140.29009363
125CSNK1A1L0.28539512
126CSNK1A10.27780426
127IKBKB0.27176330
128LYN0.27159126
129PLK20.24353964
130PRKCG0.23391382
131MAP2K60.23010645
132PRKACA0.22800768

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.21398757
2Proteasome_Homo sapiens_hsa030504.41922191
3* RNA polymerase_Homo sapiens_hsa030204.22352951
4Oxidative phosphorylation_Homo sapiens_hsa001903.73165537
5DNA replication_Homo sapiens_hsa030303.42474638
6Parkinsons disease_Homo sapiens_hsa050123.25988148
7Mismatch repair_Homo sapiens_hsa034302.86272866
8Spliceosome_Homo sapiens_hsa030402.83058078
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.81607367
10* Pyrimidine metabolism_Homo sapiens_hsa002402.66691817
11Homologous recombination_Homo sapiens_hsa034402.58556821
12Huntingtons disease_Homo sapiens_hsa050162.54516717
13Protein export_Homo sapiens_hsa030602.50324569
14Nucleotide excision repair_Homo sapiens_hsa034202.44803751
15Alzheimers disease_Homo sapiens_hsa050102.25682597
16Basal transcription factors_Homo sapiens_hsa030222.18987939
17RNA transport_Homo sapiens_hsa030132.09243141
18Base excision repair_Homo sapiens_hsa034102.02402954
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.94586607
20Fanconi anemia pathway_Homo sapiens_hsa034601.75055784
21Non-homologous end-joining_Homo sapiens_hsa034501.69155658
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.66925624
23Cell cycle_Homo sapiens_hsa041101.66706034
24RNA degradation_Homo sapiens_hsa030181.65669128
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.56724039
26* Purine metabolism_Homo sapiens_hsa002301.55812306
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.42737820
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.40314132
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39793447
30Propanoate metabolism_Homo sapiens_hsa006401.19164476
31Vitamin B6 metabolism_Homo sapiens_hsa007501.16212368
32One carbon pool by folate_Homo sapiens_hsa006701.15482837
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.08289480
34Cardiac muscle contraction_Homo sapiens_hsa042601.08182201
35Folate biosynthesis_Homo sapiens_hsa007901.07563726
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.03896375
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.95427810
38Glutathione metabolism_Homo sapiens_hsa004800.88834300
39p53 signaling pathway_Homo sapiens_hsa041150.88307889
40mRNA surveillance pathway_Homo sapiens_hsa030150.88016420
41* Epstein-Barr virus infection_Homo sapiens_hsa051690.86854405
42Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84823199
43Peroxisome_Homo sapiens_hsa041460.83911606
44Arachidonic acid metabolism_Homo sapiens_hsa005900.81391501
45Linoleic acid metabolism_Homo sapiens_hsa005910.78072474
46Sulfur relay system_Homo sapiens_hsa041220.76576206
47Systemic lupus erythematosus_Homo sapiens_hsa053220.75963427
48Fatty acid elongation_Homo sapiens_hsa000620.73368449
49Ether lipid metabolism_Homo sapiens_hsa005650.68214019
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66365597
51* Metabolic pathways_Homo sapiens_hsa011000.66312178
52Butanoate metabolism_Homo sapiens_hsa006500.59359745
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.58943000
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58580766
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56022205
56Steroid biosynthesis_Homo sapiens_hsa001000.53669589
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52789879
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.52275728
59Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51042224
60Pentose phosphate pathway_Homo sapiens_hsa000300.48604895
61beta-Alanine metabolism_Homo sapiens_hsa004100.48364630
62Regulation of autophagy_Homo sapiens_hsa041400.48067254
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47472903
64Oocyte meiosis_Homo sapiens_hsa041140.46405639
65Collecting duct acid secretion_Homo sapiens_hsa049660.45088746
66Galactose metabolism_Homo sapiens_hsa000520.44118806
67Fatty acid metabolism_Homo sapiens_hsa012120.43533738
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41399301
69Fructose and mannose metabolism_Homo sapiens_hsa000510.38554381
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.37550610
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.37406903
72Asthma_Homo sapiens_hsa053100.37354196
73Sphingolipid metabolism_Homo sapiens_hsa006000.36877022
74Tryptophan metabolism_Homo sapiens_hsa003800.36818622
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.36667488
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36644928
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35264418
78Maturity onset diabetes of the young_Homo sapiens_hsa049500.34084435
79Chemical carcinogenesis_Homo sapiens_hsa052040.33458229
80Cyanoamino acid metabolism_Homo sapiens_hsa004600.32612918
81Herpes simplex infection_Homo sapiens_hsa051680.32144501
82Arginine and proline metabolism_Homo sapiens_hsa003300.31250255
83Alcoholism_Homo sapiens_hsa050340.31006626
84Vibrio cholerae infection_Homo sapiens_hsa051100.28719327
85Fatty acid degradation_Homo sapiens_hsa000710.28627160
86Autoimmune thyroid disease_Homo sapiens_hsa053200.28485254
87Phototransduction_Homo sapiens_hsa047440.27721839
88Allograft rejection_Homo sapiens_hsa053300.26575550
89Primary immunodeficiency_Homo sapiens_hsa053400.26256229
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25454650
91Viral carcinogenesis_Homo sapiens_hsa052030.25419254
92Nitrogen metabolism_Homo sapiens_hsa009100.23698467
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.22628385
94Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.22594409
95Caffeine metabolism_Homo sapiens_hsa002320.21888345
96Rheumatoid arthritis_Homo sapiens_hsa053230.21035036
97Primary bile acid biosynthesis_Homo sapiens_hsa001200.17028100
98Synaptic vesicle cycle_Homo sapiens_hsa047210.14930182
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.14485263
100Sulfur metabolism_Homo sapiens_hsa009200.13647157
101Biosynthesis of amino acids_Homo sapiens_hsa012300.13590279
102Graft-versus-host disease_Homo sapiens_hsa053320.13226840
103Retinol metabolism_Homo sapiens_hsa008300.12731871
104Selenocompound metabolism_Homo sapiens_hsa004500.12624668
105Hematopoietic cell lineage_Homo sapiens_hsa046400.11669358
106Fat digestion and absorption_Homo sapiens_hsa049750.11631171
107Tyrosine metabolism_Homo sapiens_hsa003500.09849768
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.09616003
109N-Glycan biosynthesis_Homo sapiens_hsa005100.08336363
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.08277871
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.07688191
112Other glycan degradation_Homo sapiens_hsa005110.07303663
113Shigellosis_Homo sapiens_hsa051310.07166245
114Legionellosis_Homo sapiens_hsa051340.07119541
115Antigen processing and presentation_Homo sapiens_hsa046120.06330676
116Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.05038235
117Phenylalanine metabolism_Homo sapiens_hsa003600.04777213
118Phagosome_Homo sapiens_hsa041450.04750270
119Pyruvate metabolism_Homo sapiens_hsa006200.04319676
120HTLV-I infection_Homo sapiens_hsa051660.03867416
121NOD-like receptor signaling pathway_Homo sapiens_hsa046210.03060536
122Carbon metabolism_Homo sapiens_hsa012000.01718270
123Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.00845167
124Drug metabolism - cytochrome P450_Homo sapiens_hsa00982-0.0088132
125Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630-0.0056322
126Apoptosis_Homo sapiens_hsa04210-0.0020927

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