

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | urate metabolic process (GO:0046415) | 8.64317139 |
| 2 | phosphate ion transmembrane transport (GO:0035435) | 8.10849460 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 7.23111225 |
| 4 | aminoglycoside antibiotic metabolic process (GO:0030647) | 6.65838685 |
| 5 | response to parathyroid hormone (GO:0071107) | 6.41132895 |
| 6 | negative regulation of cAMP-mediated signaling (GO:0043951) | 6.17526107 |
| 7 | regulation of RNA export from nucleus (GO:0046831) | 5.67520541 |
| 8 | energy homeostasis (GO:0097009) | 5.56518184 |
| 9 | tachykinin receptor signaling pathway (GO:0007217) | 5.49371716 |
| 10 | transmission of nerve impulse (GO:0019226) | 5.37969936 |
| 11 | response to mercury ion (GO:0046689) | 5.36968206 |
| 12 | hyperosmotic salinity response (GO:0042538) | 5.33299872 |
| 13 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 5.32409166 |
| 14 | regulation of natural killer cell differentiation (GO:0032823) | 5.18485471 |
| 15 | regulation of hippo signaling (GO:0035330) | 5.18376151 |
| 16 | peristalsis (GO:0030432) | 5.03145445 |
| 17 | response to lead ion (GO:0010288) | 4.99379099 |
| 18 | detection of bacterium (GO:0016045) | 4.93478215 |
| 19 | phosphate ion homeostasis (GO:0055062) | 4.88064957 |
| 20 | trivalent inorganic anion homeostasis (GO:0072506) | 4.88064957 |
| 21 | regulation of catecholamine metabolic process (GO:0042069) | 4.57909108 |
| 22 | regulation of dopamine metabolic process (GO:0042053) | 4.57909108 |
| 23 | sensory perception of taste (GO:0050909) | 4.57827193 |
| 24 | positive regulation of action potential (GO:0045760) | 4.57097649 |
| 25 | histone H4-K12 acetylation (GO:0043983) | 4.50577404 |
| 26 | detection of other organism (GO:0098543) | 4.40647533 |
| 27 | regulation of nucleobase-containing compound transport (GO:0032239) | 4.38619016 |
| 28 | negative regulation of protein localization to cell surface (GO:2000009) | 4.34799391 |
| 29 | pentose metabolic process (GO:0019321) | 4.23920540 |
| 30 | negative regulation of heart rate (GO:0010459) | 4.22309381 |
| 31 | maternal behavior (GO:0042711) | 4.14695468 |
| 32 | regulation of uterine smooth muscle contraction (GO:0070472) | 4.14112679 |
| 33 | positive regulation of calcium ion import (GO:0090280) | 4.11078703 |
| 34 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 4.05966474 |
| 35 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 4.05966474 |
| 36 | behavioral response to nicotine (GO:0035095) | 3.95698891 |
| 37 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 3.83691399 |
| 38 | response to magnesium ion (GO:0032026) | 3.79024906 |
| 39 | head development (GO:0060322) | 3.75257023 |
| 40 | positive regulation of heart rate (GO:0010460) | 3.71968874 |
| 41 | parental behavior (GO:0060746) | 3.65727233 |
| 42 | regulation of G0 to G1 transition (GO:0070316) | 3.64664333 |
| 43 | opioid receptor signaling pathway (GO:0038003) | 3.62981064 |
| 44 | folic acid metabolic process (GO:0046655) | 3.62357708 |
| 45 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.53492741 |
| 46 | response to vitamin A (GO:0033189) | 3.44785243 |
| 47 | epoxygenase P450 pathway (GO:0019373) | 3.40911192 |
| 48 | glycoside metabolic process (GO:0016137) | 3.40809371 |
| 49 | indole-containing compound metabolic process (GO:0042430) | 3.40505453 |
| 50 | nephron tubule morphogenesis (GO:0072078) | 3.39598441 |
| 51 | nephron epithelium morphogenesis (GO:0072088) | 3.39598441 |
| 52 | synapsis (GO:0007129) | 3.39386364 |
| 53 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.37222952 |
| 54 | tricarboxylic acid metabolic process (GO:0072350) | 3.34102161 |
| 55 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 3.31359387 |
| 56 | sleep (GO:0030431) | 3.29949620 |
| 57 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.21764932 |
| 58 | response to growth hormone (GO:0060416) | 3.19837849 |
| 59 | histone H4 acetylation (GO:0043967) | 3.19533331 |
| 60 | CTP biosynthetic process (GO:0006241) | 3.19479669 |
| 61 | CTP metabolic process (GO:0046036) | 3.19479669 |
| 62 | negative regulation of Rho protein signal transduction (GO:0035024) | 3.17499232 |
| 63 | chromatin silencing (GO:0006342) | 3.14135689 |
| 64 | embryonic digestive tract development (GO:0048566) | 3.13693021 |
| 65 | DNA methylation involved in gamete generation (GO:0043046) | 3.13205077 |
| 66 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.12362310 |
| 67 | regulation of feeding behavior (GO:0060259) | 3.11850800 |
| 68 | pyrimidine dimer repair (GO:0006290) | 3.11159722 |
| 69 | positive regulation of protein kinase C signaling (GO:0090037) | 3.11130491 |
| 70 | detection of light stimulus involved in visual perception (GO:0050908) | 3.08119152 |
| 71 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.08119152 |
| 72 | dopamine transport (GO:0015872) | 3.03748975 |
| 73 | spermatid development (GO:0007286) | 3.02998094 |
| 74 | positive regulation of mitochondrial fission (GO:0090141) | 3.02758060 |
| 75 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.00031678 |
| 76 | otic vesicle formation (GO:0030916) | 2.95316855 |
| 77 | renal tubule morphogenesis (GO:0061333) | 2.93520628 |
| 78 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.90906335 |
| 79 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.90874921 |
| 80 | photoreceptor cell maintenance (GO:0045494) | 2.90488806 |
| 81 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.86662096 |
| 82 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.86221373 |
| 83 | grooming behavior (GO:0007625) | 2.85630797 |
| 84 | sensory perception of sound (GO:0007605) | 2.85259326 |
| 85 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.82698443 |
| 86 | response to thyroid hormone (GO:0097066) | 2.82602931 |
| 87 | positive regulation of protein export from nucleus (GO:0046827) | 2.81187079 |
| 88 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.78828269 |
| 89 | synaptic transmission, cholinergic (GO:0007271) | 2.78338581 |
| 90 | positive regulation of amino acid transport (GO:0051957) | 2.77059286 |
| 91 | cell redox homeostasis (GO:0045454) | 2.76938947 |
| 92 | maturation of 5.8S rRNA (GO:0000460) | 2.76128306 |
| 93 | rhodopsin mediated signaling pathway (GO:0016056) | 2.75851813 |
| 94 | sensory perception of mechanical stimulus (GO:0050954) | 2.75719520 |
| 95 | ribosomal large subunit biogenesis (GO:0042273) | 2.74166666 |
| 96 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.71497955 |
| 97 | methionine biosynthetic process (GO:0009086) | 2.71461219 |
| 98 | histone H2A acetylation (GO:0043968) | 12.6833282 |
| 99 | phosphate ion transport (GO:0006817) | 10.9839079 |
| 100 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 10.1315936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.43340701 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.07903532 |
| 3 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.94567329 |
| 4 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.83422402 |
| 5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.79287086 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.31257866 |
| 7 | FUS_26573619_Chip-Seq_HEK293_Human | 2.17421764 |
| 8 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.13835776 |
| 9 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.09381879 |
| 10 | GATA1_22025678_ChIP-Seq_K562_Human | 15.3410903 |
| 11 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.99466063 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.82717200 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.80418129 |
| 14 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.71696306 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.71068139 |
| 16 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.66122957 |
| 17 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.65844922 |
| 18 | RXR_22108803_ChIP-Seq_LS180_Human | 1.55731557 |
| 19 | VDR_22108803_ChIP-Seq_LS180_Human | 1.54004037 |
| 20 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.51962689 |
| 21 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.41552856 |
| 22 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.39601487 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.38812071 |
| 24 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.38254746 |
| 25 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.36959072 |
| 26 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.36472400 |
| 27 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.23647898 |
| 28 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.21732368 |
| 29 | STAT3_23295773_ChIP-Seq_U87_Human | 1.20773483 |
| 30 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.18783846 |
| 31 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.18103951 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.15282512 |
| 33 | AR_25329375_ChIP-Seq_VCAP_Human | 1.15014473 |
| 34 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.13917464 |
| 35 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.13772684 |
| 36 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.13323780 |
| 37 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.13123194 |
| 38 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12816605 |
| 39 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.12171059 |
| 40 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.10009026 |
| 41 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.09768035 |
| 42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.06815307 |
| 43 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.05706682 |
| 44 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.04291413 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.04277200 |
| 46 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.02173338 |
| 47 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.01014166 |
| 48 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.98746913 |
| 49 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.97377876 |
| 50 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97302738 |
| 51 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.97185870 |
| 52 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.95038729 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.91658213 |
| 54 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.89935702 |
| 55 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.89795408 |
| 56 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.89543470 |
| 57 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.88345485 |
| 58 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.86334173 |
| 59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.85390559 |
| 60 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.82831384 |
| 61 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.82142470 |
| 62 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.81396567 |
| 63 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81289457 |
| 64 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.80334958 |
| 65 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.80065670 |
| 66 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79182116 |
| 67 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.79155941 |
| 68 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.78629980 |
| 69 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.78376925 |
| 70 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.78091008 |
| 71 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.77721529 |
| 72 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.77721529 |
| 73 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.77233321 |
| 74 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.77187929 |
| 75 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.76005188 |
| 76 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.76003024 |
| 77 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.75841514 |
| 78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.75141375 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.75141375 |
| 80 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.74567474 |
| 81 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.74211264 |
| 82 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.72555506 |
| 83 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.72530860 |
| 84 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.72407776 |
| 85 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.72222030 |
| 86 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.71907387 |
| 87 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.71611740 |
| 88 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.70900596 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.70892458 |
| 90 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.70785951 |
| 91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.70576314 |
| 92 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.70242541 |
| 93 | * ERA_21632823_ChIP-Seq_H3396_Human | 0.69630358 |
| 94 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.69182586 |
| 95 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.68635861 |
| 96 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.68498997 |
| 97 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.68066570 |
| 98 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.68008047 |
| 99 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.67658100 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.67658100 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005377_hearing/vestibular/ear_phenot | 5.49809089 |
| 2 | MP0003878_abnormal_ear_physiology | 5.49809089 |
| 3 | MP0005397_hematopoietic_system_phenotyp | 4.42571999 |
| 4 | MP0001545_abnormal_hematopoietic_system | 4.42571999 |
| 5 | MP0005645_abnormal_hypothalamus_physiol | 3.48161641 |
| 6 | MP0004147_increased_porphyrin_level | 3.43310810 |
| 7 | MP0004510_myositis | 2.95346283 |
| 8 | MP0004808_abnormal_hematopoietic_stem | 2.55354899 |
| 9 | MP0002160_abnormal_reproductive_system | 2.52158004 |
| 10 | MP0002138_abnormal_hepatobiliary_system | 2.28413648 |
| 11 | MP0001485_abnormal_pinna_reflex | 2.22200318 |
| 12 | MP0004019_abnormal_vitamin_homeostasis | 2.22086991 |
| 13 | MP0005551_abnormal_eye_electrophysiolog | 2.14785098 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.09797271 |
| 15 | MP0002332_abnormal_exercise_endurance | 2.05208923 |
| 16 | MP0008775_abnormal_heart_ventricle | 1.99898361 |
| 17 | MP0001486_abnormal_startle_reflex | 1.99668160 |
| 18 | MP0002822_catalepsy | 1.95089192 |
| 19 | MP0003045_fibrosis | 1.93109973 |
| 20 | MP0010386_abnormal_urinary_bladder | 1.89565662 |
| 21 | MP0005367_renal/urinary_system_phenotyp | 1.83941289 |
| 22 | MP0000516_abnormal_urinary_system | 1.83941289 |
| 23 | MP0002102_abnormal_ear_morphology | 1.83634993 |
| 24 | MP0001764_abnormal_homeostasis | 1.78661374 |
| 25 | MP0005319_abnormal_enzyme/_coenzyme | 1.76313530 |
| 26 | MP0004215_abnormal_myocardial_fiber | 1.75748335 |
| 27 | MP0003136_yellow_coat_color | 1.73316011 |
| 28 | MP0002735_abnormal_chemical_nociception | 1.72345901 |
| 29 | MP0003763_abnormal_thymus_physiology | 1.68134451 |
| 30 | MP0000538_abnormal_urinary_bladder | 1.66559119 |
| 31 | MP0005410_abnormal_fertilization | 1.62493915 |
| 32 | MP0005389_reproductive_system_phenotype | 1.58573854 |
| 33 | MP0009333_abnormal_splenocyte_physiolog | 1.56956908 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.51914226 |
| 35 | MP0000427_abnormal_hair_cycle | 1.51658051 |
| 36 | MP0008877_abnormal_DNA_methylation | 1.49398096 |
| 37 | MP0009278_abnormal_bone_marrow | 1.43930128 |
| 38 | MP0003283_abnormal_digestive_organ | 1.42713099 |
| 39 | MP0000383_abnormal_hair_follicle | 1.42130450 |
| 40 | MP0004085_abnormal_heartbeat | 1.38053934 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.35123495 |
| 42 | MP0009765_abnormal_xenobiotic_induced | 1.31814732 |
| 43 | MP0005220_abnormal_exocrine_pancreas | 1.31233428 |
| 44 | MP0006035_abnormal_mitochondrial_morpho | 1.30506167 |
| 45 | MP0005647_abnormal_sex_gland | 1.30322470 |
| 46 | MP0002733_abnormal_thermal_nociception | 1.24576772 |
| 47 | MP0006292_abnormal_olfactory_placode | 1.23927471 |
| 48 | MP0009672_abnormal_birth_weight | 1.20503088 |
| 49 | MP0006138_congestive_heart_failure | 1.16441018 |
| 50 | MP0005253_abnormal_eye_physiology | 1.13762485 |
| 51 | MP0000678_abnormal_parathyroid_gland | 1.12933567 |
| 52 | MP0000749_muscle_degeneration | 1.10799535 |
| 53 | MP0004133_heterotaxia | 1.10778810 |
| 54 | MP0001348_abnormal_lacrimal_gland | 1.09165525 |
| 55 | MP0005195_abnormal_posterior_eye | 1.08762209 |
| 56 | MP0004782_abnormal_surfactant_physiolog | 1.06152411 |
| 57 | MP0010678_abnormal_skin_adnexa | 1.04624664 |
| 58 | MP0003880_abnormal_central_pattern | 0.93320572 |
| 59 | MP0001963_abnormal_hearing_physiology | 0.92941944 |
| 60 | MP0003698_abnormal_male_reproductive | 0.92669408 |
| 61 | MP0002184_abnormal_innervation | 0.90144285 |
| 62 | MP0010094_abnormal_chromosome_stability | 0.86376538 |
| 63 | MP0003252_abnormal_bile_duct | 0.85637495 |
| 64 | MP0002837_dystrophic_cardiac_calcinosis | 0.83728811 |
| 65 | MP0001970_abnormal_pain_threshold | 0.82748932 |
| 66 | MP0009046_muscle_twitch | 0.82337745 |
| 67 | MP0010368_abnormal_lymphatic_system | 0.81873336 |
| 68 | MP0003959_abnormal_lean_body | 0.81429493 |
| 69 | MP0004858_abnormal_nervous_system | 0.81212048 |
| 70 | MP0001929_abnormal_gametogenesis | 0.78588936 |
| 71 | MP0001765_abnormal_ion_homeostasis | 0.78020556 |
| 72 | MP0001905_abnormal_dopamine_level | 0.77024722 |
| 73 | MP0002168_other_aberrant_phenotype | 0.75648050 |
| 74 | MP0003635_abnormal_synaptic_transmissio | 0.74566767 |
| 75 | MP0000631_abnormal_neuroendocrine_gland | 0.72507856 |
| 76 | MP0000604_amyloidosis | 0.72343598 |
| 77 | MP0009745_abnormal_behavioral_response | 0.71544380 |
| 78 | MP0000230_abnormal_systemic_arterial | 0.71015382 |
| 79 | MP0005360_urolithiasis | 0.70820518 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.68895465 |
| 81 | MP0008058_abnormal_DNA_repair | 0.68118423 |
| 82 | MP0005636_abnormal_mineral_homeostasis | 0.68037107 |
| 83 | MP0001984_abnormal_olfaction | 0.67580669 |
| 84 | MP0000049_abnormal_middle_ear | 0.67436217 |
| 85 | MP0001919_abnormal_reproductive_system | 0.65841230 |
| 86 | MP0001986_abnormal_taste_sensitivity | 0.64492322 |
| 87 | MP0002229_neurodegeneration | 0.63883900 |
| 88 | MP0000026_abnormal_inner_ear | 0.62656823 |
| 89 | MP0002752_abnormal_somatic_nervous | 0.62642938 |
| 90 | MP0002063_abnormal_learning/memory/cond | 0.62481079 |
| 91 | MP0004145_abnormal_muscle_electrophysio | 0.62401216 |
| 92 | MP0003786_premature_aging | 0.60898984 |
| 93 | MP0000465_gastrointestinal_hemorrhage | 0.59524934 |
| 94 | MP0001756_abnormal_urination | 0.58960031 |
| 95 | MP0001664_abnormal_digestion | 0.58022892 |
| 96 | MP0002098_abnormal_vibrissa_morphology | 0.57964370 |
| 97 | MP0000751_myopathy | 0.57641330 |
| 98 | MP0000372_irregular_coat_pigmentation | 0.55708621 |
| 99 | MP0004885_abnormal_endolymph | 0.55638410 |
| 100 | MP0001145_abnormal_male_reproductive | 0.55634283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proximal tubulopathy (HP:0000114) | 7.85933412 |
| 2 | Severe visual impairment (HP:0001141) | 7.18201866 |
| 3 | Pendular nystagmus (HP:0012043) | 6.98271069 |
| 4 | Popliteal pterygium (HP:0009756) | 5.21406020 |
| 5 | Congenital stationary night blindness (HP:0007642) | 4.94752485 |
| 6 | True hermaphroditism (HP:0010459) | 4.84215300 |
| 7 | Pancreatic fibrosis (HP:0100732) | 4.61999044 |
| 8 | Pancreatic cysts (HP:0001737) | 4.17489898 |
| 9 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.16134047 |
| 10 | Abnormality of urine glucose concentration (HP:0011016) | 4.01084547 |
| 11 | Glycosuria (HP:0003076) | 4.01084547 |
| 12 | Myokymia (HP:0002411) | 3.99547122 |
| 13 | Abnormality of placental membranes (HP:0011409) | 3.75388106 |
| 14 | Amniotic constriction ring (HP:0009775) | 3.75388106 |
| 15 | Cystic liver disease (HP:0006706) | 3.64519000 |
| 16 | Parakeratosis (HP:0001036) | 3.61988090 |
| 17 | Attenuation of retinal blood vessels (HP:0007843) | 3.51654481 |
| 18 | Abolished electroretinogram (ERG) (HP:0000550) | 3.49677508 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.30473079 |
| 20 | Acute lymphatic leukemia (HP:0006721) | 3.26246446 |
| 21 | Keratoconus (HP:0000563) | 3.13817739 |
| 22 | Increased corneal curvature (HP:0100692) | 3.13817739 |
| 23 | Optic nerve hypoplasia (HP:0000609) | 3.06764449 |
| 24 | Genetic anticipation (HP:0003743) | 2.88593456 |
| 25 | Renal cortical cysts (HP:0000803) | 2.87051033 |
| 26 | Sclerocornea (HP:0000647) | 2.86912027 |
| 27 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.81039265 |
| 28 | Abnormality of macular pigmentation (HP:0008002) | 2.79143350 |
| 29 | Abnormality of the anterior horn cell (HP:0006802) | 2.77985175 |
| 30 | Degeneration of anterior horn cells (HP:0002398) | 2.77985175 |
| 31 | Hyperphosphaturia (HP:0003109) | 2.77094942 |
| 32 | Long clavicles (HP:0000890) | 2.76907387 |
| 33 | Fetal akinesia sequence (HP:0001989) | 2.74574225 |
| 34 | Bile duct proliferation (HP:0001408) | 2.74156740 |
| 35 | Abnormal biliary tract physiology (HP:0012439) | 2.74156740 |
| 36 | Hyperkalemia (HP:0002153) | 2.70711958 |
| 37 | Male pseudohermaphroditism (HP:0000037) | 2.68683059 |
| 38 | Hypoglycemic coma (HP:0001325) | 2.66163617 |
| 39 | Abnormality of DNA repair (HP:0003254) | 2.63808757 |
| 40 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.62713214 |
| 41 | Aplasia of the musculature (HP:0100854) | 2.62172621 |
| 42 | Poikiloderma (HP:0001029) | 2.60939049 |
| 43 | Congenital sensorineural hearing impairment (HP:0008527) | 2.55694067 |
| 44 | Furrowed tongue (HP:0000221) | 2.53579108 |
| 45 | Anencephaly (HP:0002323) | 2.50787085 |
| 46 | Decreased central vision (HP:0007663) | 2.48796811 |
| 47 | Postaxial foot polydactyly (HP:0001830) | 2.39800368 |
| 48 | Abnormal number of erythroid precursors (HP:0012131) | 2.39734536 |
| 49 | Malignant hyperthermia (HP:0002047) | 2.38506362 |
| 50 | Cystic hygroma (HP:0000476) | 2.38387207 |
| 51 | Neonatal respiratory distress (HP:0002643) | 2.38019493 |
| 52 | Diaphragmatic weakness (HP:0009113) | 2.30318475 |
| 53 | Abnormality of the labia majora (HP:0012881) | 2.29012299 |
| 54 | Congenital hepatic fibrosis (HP:0002612) | 2.28807351 |
| 55 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.22143504 |
| 56 | J-shaped sella turcica (HP:0002680) | 2.18969081 |
| 57 | Rib fusion (HP:0000902) | 2.17666442 |
| 58 | Abnormality of the renal collecting system (HP:0004742) | 2.17390151 |
| 59 | Chorioretinal atrophy (HP:0000533) | 2.15993959 |
| 60 | Abnormal urine phosphate concentration (HP:0012599) | 2.13965957 |
| 61 | Hypercalciuria (HP:0002150) | 2.12382940 |
| 62 | Progressive cerebellar ataxia (HP:0002073) | 2.08293694 |
| 63 | Nausea (HP:0002018) | 2.06286781 |
| 64 | Rickets (HP:0002748) | 2.05641354 |
| 65 | Type 2 muscle fiber atrophy (HP:0003554) | 2.04185388 |
| 66 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.03809690 |
| 67 | Stenosis of the external auditory canal (HP:0000402) | 2.03406639 |
| 68 | Nonprogressive disorder (HP:0003680) | 2.02597190 |
| 69 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.02131210 |
| 70 | Generalized aminoaciduria (HP:0002909) | 10.4528827 |
| 71 | Agnosia (HP:0010524) | 1.96826738 |
| 72 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.96422371 |
| 73 | Decreased circulating renin level (HP:0003351) | 1.94168453 |
| 74 | Abnormality of homocysteine metabolism (HP:0010919) | 1.94157598 |
| 75 | Homocystinuria (HP:0002156) | 1.94157598 |
| 76 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92588509 |
| 77 | Abnormality of the renal cortex (HP:0011035) | 1.89964551 |
| 78 | Nephronophthisis (HP:0000090) | 1.88015186 |
| 79 | Abnormality of chloride homeostasis (HP:0011422) | 1.86258344 |
| 80 | Preaxial hand polydactyly (HP:0001177) | 1.85097198 |
| 81 | Chronic bronchitis (HP:0004469) | 1.81976950 |
| 82 | Clumsiness (HP:0002312) | 1.77930058 |
| 83 | Resting tremor (HP:0002322) | 1.76391300 |
| 84 | Recurrent corneal erosions (HP:0000495) | 1.75997950 |
| 85 | Macular degeneration (HP:0000608) | 1.75316533 |
| 86 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.74252286 |
| 87 | Occipital encephalocele (HP:0002085) | 1.67768284 |
| 88 | Abnormality of the renal medulla (HP:0100957) | 1.67386272 |
| 89 | Squamous cell carcinoma (HP:0002860) | 1.65480824 |
| 90 | Neonatal death (HP:0003811) | 1.64958220 |
| 91 | Chronic hepatic failure (HP:0100626) | 1.64596338 |
| 92 | Facial diplegia (HP:0001349) | 1.64058770 |
| 93 | Abnormal auditory evoked potentials (HP:0006958) | 1.63586579 |
| 94 | Pterygium (HP:0001059) | 1.61577823 |
| 95 | Muscle fiber atrophy (HP:0100295) | 1.60144133 |
| 96 | Posterior subcapsular cataract (HP:0007787) | 1.58221976 |
| 97 | Sloping forehead (HP:0000340) | 1.55389918 |
| 98 | Hyperactive renin-angiotensin system (HP:0000841) | 1.55108145 |
| 99 | Deformed sella turcica (HP:0002681) | 1.51140438 |
| 100 | Postaxial hand polydactyly (HP:0001162) | 1.50973823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 6.12509165 |
| 2 | FRK | 5.67534738 |
| 3 | ADRBK2 | 3.89485629 |
| 4 | TXK | 3.76557026 |
| 5 | GRK7 | 2.64623159 |
| 6 | PINK1 | 2.62161380 |
| 7 | FGFR2 | 2.54529870 |
| 8 | AURKA | 2.36245402 |
| 9 | MAP4K1 | 2.30786518 |
| 10 | ZAK | 1.94597213 |
| 11 | MOS | 1.74013197 |
| 12 | TGFBR2 | 1.60424760 |
| 13 | TRIM28 | 1.59037089 |
| 14 | BMPR1B | 1.56010120 |
| 15 | TAOK3 | 1.46911399 |
| 16 | NTRK3 | 1.45032223 |
| 17 | BCKDK | 1.39027347 |
| 18 | JAK3 | 1.33615893 |
| 19 | TLK1 | 1.31517831 |
| 20 | GRK5 | 1.27885030 |
| 21 | WNK3 | 1.18496425 |
| 22 | CDK12 | 1.15559216 |
| 23 | CHEK2 | 1.12866753 |
| 24 | PLK4 | 1.10534308 |
| 25 | DAPK2 | 1.07239619 |
| 26 | TNK2 | 1.07054467 |
| 27 | RPS6KA4 | 1.04376401 |
| 28 | CSNK1G3 | 1.04090139 |
| 29 | BTK | 1.01332336 |
| 30 | VRK1 | 0.99398565 |
| 31 | INSRR | 0.95775100 |
| 32 | MAP4K2 | 0.93187707 |
| 33 | SYK | 0.91985959 |
| 34 | TYRO3 | 0.88556763 |
| 35 | TIE1 | 0.87082920 |
| 36 | CSNK1G1 | 0.85948925 |
| 37 | PRKACB | 0.85713679 |
| 38 | GRK1 | 0.85321973 |
| 39 | PRKG2 | 0.85291065 |
| 40 | MAP3K7 | 0.84629225 |
| 41 | PRKCD | 0.82664724 |
| 42 | MAP2K6 | 0.82088773 |
| 43 | MINK1 | 0.81724886 |
| 44 | RPS6KA5 | 0.81326570 |
| 45 | MAP2K7 | 0.80938055 |
| 46 | MAPK13 | 0.80902970 |
| 47 | CSNK1A1L | 0.80672254 |
| 48 | MYLK | 0.76838238 |
| 49 | CHEK1 | 0.76312624 |
| 50 | MAPK15 | 0.76096858 |
| 51 | PRKCG | 0.75056456 |
| 52 | OBSCN | 0.72495452 |
| 53 | PRKD3 | 0.72191563 |
| 54 | MARK3 | 0.69750511 |
| 55 | DYRK1B | 0.69595878 |
| 56 | KIT | 0.69117650 |
| 57 | CSNK1G2 | 0.67475273 |
| 58 | TESK1 | 0.63293378 |
| 59 | KDR | 0.62567437 |
| 60 | CDK8 | 0.62103737 |
| 61 | LYN | 0.61327459 |
| 62 | NTRK2 | 0.60614942 |
| 63 | CSNK1A1 | 0.59852606 |
| 64 | LCK | 0.55613637 |
| 65 | MATK | 0.54052415 |
| 66 | PRKACA | 0.53245313 |
| 67 | TGFBR1 | 0.52454340 |
| 68 | ACVR1B | 0.52399194 |
| 69 | DDR2 | 0.52019318 |
| 70 | PRKD2 | 0.51932597 |
| 71 | PRKCH | 0.51925024 |
| 72 | MAPK8 | 0.51004382 |
| 73 | STK11 | 0.50970296 |
| 74 | DYRK2 | 0.50922670 |
| 75 | ADRBK1 | 0.50714649 |
| 76 | EGFR | 0.50427477 |
| 77 | PKN1 | 0.50296092 |
| 78 | BCR | 0.49617993 |
| 79 | PLK3 | 0.47770767 |
| 80 | DAPK3 | 0.47284302 |
| 81 | STK10 | 0.46185289 |
| 82 | MAPK10 | 0.45751964 |
| 83 | CDC7 | 0.44410400 |
| 84 | INSR | 0.44333488 |
| 85 | ZAP70 | 0.42101852 |
| 86 | PTK2B | 0.42037620 |
| 87 | CSNK2A1 | 0.42003957 |
| 88 | OXSR1 | 0.41666473 |
| 89 | RPS6KB1 | 0.40568415 |
| 90 | CASK | 0.40547313 |
| 91 | PDGFRA | 0.37674265 |
| 92 | MAPK4 | 0.37598518 |
| 93 | WEE1 | 0.37486821 |
| 94 | CSNK2A2 | 0.37229835 |
| 95 | PRKACG | 0.35520827 |
| 96 | CSNK1E | 0.34166234 |
| 97 | JAK2 | 0.33313838 |
| 98 | CDK11A | 0.31608802 |
| 99 | PLK1 | 0.31261358 |
| 100 | MUSK | 0.30988549 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Renin-angiotensin system_Homo sapiens_hsa04614 | 5.87335585 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 4.47708118 |
| 3 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.99858969 |
| 4 | Taste transduction_Homo sapiens_hsa04742 | 2.80494736 |
| 5 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.61319542 |
| 6 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.39177580 |
| 7 | Nicotine addiction_Homo sapiens_hsa05033 | 2.37705446 |
| 8 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.30774548 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.29694138 |
| 10 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.28904379 |
| 11 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.28661426 |
| 12 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.19577047 |
| 13 | Retinol metabolism_Homo sapiens_hsa00830 | 2.18874097 |
| 14 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.99954702 |
| 15 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.88989020 |
| 16 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.78089380 |
| 17 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.76347985 |
| 18 | Ribosome_Homo sapiens_hsa03010 | 1.67368556 |
| 19 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.66925938 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.65404958 |
| 21 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.60830067 |
| 22 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.52605519 |
| 23 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.50286605 |
| 24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.47679159 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.47593070 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.40364784 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.27854762 |
| 28 | Morphine addiction_Homo sapiens_hsa05032 | 1.25983849 |
| 29 | Sulfur relay system_Homo sapiens_hsa04122 | 1.23739725 |
| 30 | Cocaine addiction_Homo sapiens_hsa05030 | 1.20618702 |
| 31 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.16499408 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.13831197 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.04312282 |
| 34 | Gap junction_Homo sapiens_hsa04540 | 1.02696081 |
| 35 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.02037688 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 0.98571961 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 0.96988886 |
| 38 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.93363392 |
| 39 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.87183482 |
| 40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.85312761 |
| 41 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.83647436 |
| 42 | Circadian entrainment_Homo sapiens_hsa04713 | 0.81506328 |
| 43 | Renin secretion_Homo sapiens_hsa04924 | 0.79626642 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.78767464 |
| 45 | GABAergic synapse_Homo sapiens_hsa04727 | 0.76815023 |
| 46 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.76368209 |
| 47 | Salivary secretion_Homo sapiens_hsa04970 | 0.74290973 |
| 48 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.74162573 |
| 49 | Asthma_Homo sapiens_hsa05310 | 0.73406429 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.69071903 |
| 51 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.69059060 |
| 52 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68519865 |
| 53 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.67216614 |
| 54 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.65833134 |
| 55 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.65638923 |
| 56 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64792778 |
| 57 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.64037116 |
| 58 | Alcoholism_Homo sapiens_hsa05034 | 0.62783226 |
| 59 | ABC transporters_Homo sapiens_hsa02010 | 0.59554802 |
| 60 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.57153107 |
| 61 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.56995542 |
| 62 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.56550394 |
| 63 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.54702367 |
| 64 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.54371404 |
| 65 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.54198381 |
| 66 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.53076829 |
| 67 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.49941997 |
| 68 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.49664943 |
| 69 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.48189142 |
| 70 | Spliceosome_Homo sapiens_hsa03040 | 0.46844474 |
| 71 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46345614 |
| 72 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.45708314 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.43725756 |
| 74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43640209 |
| 75 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.43596243 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42690913 |
| 77 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.41297301 |
| 78 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.40202592 |
| 79 | Proteasome_Homo sapiens_hsa03050 | 0.39960311 |
| 80 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.39850392 |
| 81 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.37212083 |
| 82 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36316824 |
| 83 | Parkinsons disease_Homo sapiens_hsa05012 | 0.35041747 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.34835411 |
| 85 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.34431021 |
| 86 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.29711669 |
| 87 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.28509063 |
| 88 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.28444859 |
| 89 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.27956693 |
| 90 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.27878842 |
| 91 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27877327 |
| 92 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.27557820 |
| 93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26320783 |
| 94 | Base excision repair_Homo sapiens_hsa03410 | 0.25274925 |
| 95 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24334859 |
| 96 | Allograft rejection_Homo sapiens_hsa05330 | 0.22842539 |
| 97 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22412738 |
| 98 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.20964710 |
| 99 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.18526242 |
| 100 | Pertussis_Homo sapiens_hsa05133 | 0.18294161 |

