

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | iron ion import (GO:0097286) | 6.99730791 |
| 2 | adaptation of signaling pathway (GO:0023058) | 6.13308565 |
| 3 | negative regulation of sodium ion transport (GO:0010766) | 5.44809108 |
| 4 | retinal metabolic process (GO:0042574) | 5.35140699 |
| 5 | import into cell (GO:0098657) | 5.22872928 |
| 6 | negative regulation of protein localization to cell surface (GO:2000009) | 4.75842560 |
| 7 | branching involved in prostate gland morphogenesis (GO:0060442) | 4.65592008 |
| 8 | negative regulation of systemic arterial blood pressure (GO:0003085) | 4.55921386 |
| 9 | positive regulation of glycolytic process (GO:0045821) | 4.46917038 |
| 10 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 4.41319167 |
| 11 | detection of temperature stimulus (GO:0016048) | 4.31178234 |
| 12 | indole-containing compound catabolic process (GO:0042436) | 4.11282960 |
| 13 | indolalkylamine catabolic process (GO:0046218) | 4.11282960 |
| 14 | tryptophan catabolic process (GO:0006569) | 4.11282960 |
| 15 | interkinetic nuclear migration (GO:0022027) | 4.07124751 |
| 16 | lung lobe morphogenesis (GO:0060463) | 4.06072857 |
| 17 | regulation of hippo signaling (GO:0035330) | 4.04113783 |
| 18 | phospholipid scrambling (GO:0017121) | 3.98584004 |
| 19 | establishment of protein localization to Golgi (GO:0072600) | 3.97353942 |
| 20 | biotin metabolic process (GO:0006768) | 3.96881228 |
| 21 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.96780038 |
| 22 | protein homotrimerization (GO:0070207) | 3.93344236 |
| 23 | lung vasculature development (GO:0060426) | 3.86449904 |
| 24 | indolalkylamine metabolic process (GO:0006586) | 3.79066429 |
| 25 | artery development (GO:0060840) | 3.77402795 |
| 26 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 3.77329378 |
| 27 | tryptophan metabolic process (GO:0006568) | 3.64794674 |
| 28 | kynurenine metabolic process (GO:0070189) | 3.61408955 |
| 29 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 3.60738829 |
| 30 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.60498356 |
| 31 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.60498356 |
| 32 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.60498356 |
| 33 | benzene-containing compound metabolic process (GO:0042537) | 3.53886051 |
| 34 | positive regulation of steroid hormone secretion (GO:2000833) | 3.53427275 |
| 35 | diterpenoid biosynthetic process (GO:0016102) | 3.52554174 |
| 36 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.45573143 |
| 37 | endothelial cell chemotaxis (GO:0035767) | 3.37985614 |
| 38 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.32379743 |
| 39 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 3.19930078 |
| 40 | regulation of gene silencing by RNA (GO:0060966) | 3.18777983 |
| 41 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.18777983 |
| 42 | regulation of gene silencing by miRNA (GO:0060964) | 3.18777983 |
| 43 | reflex (GO:0060004) | 3.11217209 |
| 44 | response to cold (GO:0009409) | 3.08933559 |
| 45 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 3.08407639 |
| 46 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.05580301 |
| 47 | cellular biogenic amine catabolic process (GO:0042402) | 3.04967952 |
| 48 | amine catabolic process (GO:0009310) | 3.04967952 |
| 49 | tachykinin receptor signaling pathway (GO:0007217) | 3.04553125 |
| 50 | positive regulation of glycogen biosynthetic process (GO:0045725) | 3.02647772 |
| 51 | regulation of establishment of cell polarity (GO:2000114) | 3.01576913 |
| 52 | prostate gland growth (GO:0060736) | 2.96169100 |
| 53 | protein targeting to Golgi (GO:0000042) | 2.95863893 |
| 54 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.90569001 |
| 55 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.90400408 |
| 56 | signal peptide processing (GO:0006465) | 2.90005865 |
| 57 | exocrine pancreas development (GO:0031017) | 2.87860817 |
| 58 | protein targeting to lysosome (GO:0006622) | 2.87450647 |
| 59 | establishment of protein localization to vacuole (GO:0072666) | 2.87450647 |
| 60 | protein targeting to vacuole (GO:0006623) | 2.87450647 |
| 61 | cellular response to ethanol (GO:0071361) | 2.84154606 |
| 62 | retinol metabolic process (GO:0042572) | 2.83865928 |
| 63 | positive regulation of digestive system process (GO:0060456) | 2.81792922 |
| 64 | carnitine transmembrane transport (GO:1902603) | 2.81676772 |
| 65 | righting reflex (GO:0060013) | 2.81491519 |
| 66 | copper ion transport (GO:0006825) | 2.80519243 |
| 67 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.80343469 |
| 68 | quaternary ammonium group transport (GO:0015697) | 2.80006550 |
| 69 | prostate gland epithelium morphogenesis (GO:0060740) | 2.79392336 |
| 70 | carnitine transport (GO:0015879) | 2.75085211 |
| 71 | amino-acid betaine transport (GO:0015838) | 2.75085211 |
| 72 | cellular ketone body metabolic process (GO:0046950) | 2.75054992 |
| 73 | DNA methylation involved in gamete generation (GO:0043046) | 2.74698029 |
| 74 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.72912921 |
| 75 | regulation of endocrine process (GO:0044060) | 2.72601005 |
| 76 | adenosine metabolic process (GO:0046085) | 2.71084758 |
| 77 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.65275213 |
| 78 | regulation of membrane lipid distribution (GO:0097035) | 2.64215957 |
| 79 | positive regulation of developmental pigmentation (GO:0048087) | 2.64070979 |
| 80 | terpenoid biosynthetic process (GO:0016114) | 2.63226258 |
| 81 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.62895698 |
| 82 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.62895698 |
| 83 | phospholipid translocation (GO:0045332) | 2.59749853 |
| 84 | lipid translocation (GO:0034204) | 2.59749853 |
| 85 | toxin transport (GO:1901998) | 2.59446772 |
| 86 | neural tube formation (GO:0001841) | 2.59019782 |
| 87 | protein localization to Golgi apparatus (GO:0034067) | 2.58234971 |
| 88 | branched-chain amino acid catabolic process (GO:0009083) | 2.57278848 |
| 89 | positive regulation of glycogen metabolic process (GO:0070875) | 2.57113537 |
| 90 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.56139336 |
| 91 | intestinal epithelial cell development (GO:0060576) | 2.51711155 |
| 92 | histone H3-K4 trimethylation (GO:0080182) | 2.51007024 |
| 93 | indole-containing compound metabolic process (GO:0042430) | 2.49451370 |
| 94 | pharyngeal system development (GO:0060037) | 2.49124096 |
| 95 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.48264108 |
| 96 | positive regulation of fatty acid oxidation (GO:0046321) | 2.46466492 |
| 97 | snRNA transcription (GO:0009301) | 2.46068285 |
| 98 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.45972199 |
| 99 | amine biosynthetic process (GO:0009309) | 2.45209435 |
| 100 | mammary gland development (GO:0030879) | 2.44039750 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.84561415 |
| 2 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 3.34906506 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.10206830 |
| 4 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 3.00899690 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.95495505 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.66002270 |
| 7 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.53917398 |
| 8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.48088045 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.40049162 |
| 10 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.33204615 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.28000994 |
| 12 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 2.22017281 |
| 13 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.15277595 |
| 14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.15195117 |
| 15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.07378494 |
| 16 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.06313555 |
| 17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.05123347 |
| 18 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.97571252 |
| 19 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.96485699 |
| 20 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.91250734 |
| 21 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.89764182 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86021570 |
| 23 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.85932066 |
| 24 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.83322906 |
| 25 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.83041942 |
| 26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.81380888 |
| 27 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.79337278 |
| 28 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.75693982 |
| 29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.72967570 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.71948417 |
| 31 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.66688642 |
| 32 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.65482795 |
| 33 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.65482795 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.64005383 |
| 35 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.63792748 |
| 36 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.63792748 |
| 37 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.63195924 |
| 38 | TCF4_23295773_ChIP-Seq_U87_Human | 1.63000257 |
| 39 | STAT3_23295773_ChIP-Seq_U87_Human | 1.62134898 |
| 40 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.59775296 |
| 41 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.58211841 |
| 42 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.58113973 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55305972 |
| 44 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.52484004 |
| 45 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.49301221 |
| 46 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.48308314 |
| 47 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.46096094 |
| 48 | AR_25329375_ChIP-Seq_VCAP_Human | 1.45972234 |
| 49 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.44510559 |
| 50 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.43404973 |
| 51 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.42853845 |
| 52 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.42359000 |
| 53 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.41155530 |
| 54 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.38472503 |
| 55 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.38198426 |
| 56 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.37198246 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36464383 |
| 58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.34286588 |
| 59 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.31730094 |
| 60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30958048 |
| 61 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26088510 |
| 62 | RXR_22108803_ChIP-Seq_LS180_Human | 1.24697970 |
| 63 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.23030765 |
| 64 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.21316906 |
| 65 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.19566708 |
| 66 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.18434019 |
| 67 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.17318390 |
| 68 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17030948 |
| 69 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.16526610 |
| 70 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.16027049 |
| 71 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.14769180 |
| 72 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.14415604 |
| 73 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.14250054 |
| 74 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.13671938 |
| 75 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.11517452 |
| 76 | FUS_26573619_Chip-Seq_HEK293_Human | 1.08987626 |
| 77 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.08942814 |
| 78 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.08766079 |
| 79 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.08766079 |
| 80 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.08739577 |
| 81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07648762 |
| 82 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.07588976 |
| 83 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07341002 |
| 84 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06977111 |
| 85 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.05489399 |
| 86 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05069183 |
| 87 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03558861 |
| 88 | TP53_16413492_ChIP-PET_HCT116_Human | 1.03152794 |
| 89 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.02953422 |
| 90 | AR_20517297_ChIP-Seq_VCAP_Human | 1.02635231 |
| 91 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.01909293 |
| 92 | TBL1_22424771_ChIP-Seq_293T_Human | 0.98582852 |
| 93 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.96440741 |
| 94 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94814928 |
| 95 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.94626435 |
| 96 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.94594199 |
| 97 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92725159 |
| 98 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.92100043 |
| 99 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91673129 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91227881 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002736_abnormal_nociception_after | 5.24033987 |
| 2 | MP0005167_abnormal_blood-brain_barrier | 4.61390362 |
| 3 | MP0004043_abnormal_pH_regulation | 4.57622319 |
| 4 | MP0001968_abnormal_touch/_nociception | 4.02671226 |
| 5 | MP0003011_delayed_dark_adaptation | 3.54593601 |
| 6 | MP0002234_abnormal_pharynx_morphology | 3.28326446 |
| 7 | MP0002735_abnormal_chemical_nociception | 3.20437938 |
| 8 | MP0008057_abnormal_DNA_replication | 3.16474997 |
| 9 | MP0005646_abnormal_pituitary_gland | 2.43738243 |
| 10 | MP0003045_fibrosis | 2.41858590 |
| 11 | MP0005551_abnormal_eye_electrophysiolog | 2.22834286 |
| 12 | MP0005310_abnormal_salivary_gland | 1.92917958 |
| 13 | MP0005670_abnormal_white_adipose | 1.91745110 |
| 14 | MP0001501_abnormal_sleep_pattern | 1.83940931 |
| 15 | MP0002733_abnormal_thermal_nociception | 1.79062188 |
| 16 | MP0003718_maternal_effect | 1.71294342 |
| 17 | MP0003195_calcinosis | 1.51862337 |
| 18 | MP0003136_yellow_coat_color | 1.51817089 |
| 19 | MP0001756_abnormal_urination | 1.48132563 |
| 20 | MP0000383_abnormal_hair_follicle | 1.46992667 |
| 21 | MP0000230_abnormal_systemic_arterial | 1.46162351 |
| 22 | MP0001664_abnormal_digestion | 1.45508952 |
| 23 | MP0005085_abnormal_gallbladder_physiolo | 1.45419026 |
| 24 | MP0002876_abnormal_thyroid_physiology | 1.38798774 |
| 25 | MP0003646_muscle_fatigue | 1.38493985 |
| 26 | MP0000538_abnormal_urinary_bladder | 1.34015919 |
| 27 | MP0005253_abnormal_eye_physiology | 1.33705060 |
| 28 | MP0001765_abnormal_ion_homeostasis | 1.32728049 |
| 29 | MP0005647_abnormal_sex_gland | 1.30882119 |
| 30 | MP0000631_abnormal_neuroendocrine_gland | 1.29450561 |
| 31 | MP0002166_altered_tumor_susceptibility | 1.27536266 |
| 32 | MP0001970_abnormal_pain_threshold | 1.25867039 |
| 33 | MP0005395_other_phenotype | 1.23370595 |
| 34 | MP0001666_abnormal_nutrient_absorption | 1.20563916 |
| 35 | MP0002138_abnormal_hepatobiliary_system | 1.19369992 |
| 36 | MP0002822_catalepsy | 1.16439123 |
| 37 | MP0004145_abnormal_muscle_electrophysio | 1.13348040 |
| 38 | MP0005410_abnormal_fertilization | 1.11300283 |
| 39 | MP0003698_abnormal_male_reproductive | 1.09768327 |
| 40 | MP0002168_other_aberrant_phenotype | 1.08943106 |
| 41 | MP0000613_abnormal_salivary_gland | 1.08889482 |
| 42 | MP0008995_early_reproductive_senescence | 1.08733167 |
| 43 | MP0008877_abnormal_DNA_methylation | 1.08656486 |
| 44 | MP0002090_abnormal_vision | 1.07353465 |
| 45 | MP0010329_abnormal_lipoprotein_level | 1.06979573 |
| 46 | MP0005220_abnormal_exocrine_pancreas | 1.02326276 |
| 47 | MP0005636_abnormal_mineral_homeostasis | 1.01837124 |
| 48 | MP0002102_abnormal_ear_morphology | 1.01639257 |
| 49 | MP0000569_abnormal_digit_pigmentation | 1.00339286 |
| 50 | MP0002653_abnormal_ependyma_morphology | 0.99258384 |
| 51 | MP0003937_abnormal_limbs/digits/tail_de | 0.99159421 |
| 52 | MP0001188_hyperpigmentation | 0.99139437 |
| 53 | MP0002557_abnormal_social/conspecific_i | 0.97690021 |
| 54 | MP0005360_urolithiasis | 0.96628247 |
| 55 | MP0000516_abnormal_urinary_system | 0.96467193 |
| 56 | MP0005367_renal/urinary_system_phenotyp | 0.96467193 |
| 57 | MP0008961_abnormal_basal_metabolism | 0.94680398 |
| 58 | MP0010386_abnormal_urinary_bladder | 0.94065361 |
| 59 | MP0001486_abnormal_startle_reflex | 0.93799658 |
| 60 | MP0000427_abnormal_hair_cycle | 0.93381203 |
| 61 | MP0003633_abnormal_nervous_system | 0.93231999 |
| 62 | MP0004085_abnormal_heartbeat | 0.92273829 |
| 63 | MP0001873_stomach_inflammation | 0.91733292 |
| 64 | MP0001929_abnormal_gametogenesis | 0.91513124 |
| 65 | MP0003879_abnormal_hair_cell | 0.89133294 |
| 66 | MP0000372_irregular_coat_pigmentation | 0.88950568 |
| 67 | MP0002837_dystrophic_cardiac_calcinosis | 0.88159715 |
| 68 | MP0005645_abnormal_hypothalamus_physiol | 0.87901451 |
| 69 | MP0002067_abnormal_sensory_capabilities | 0.87698336 |
| 70 | MP0004858_abnormal_nervous_system | 0.86060404 |
| 71 | MP0002160_abnormal_reproductive_system | 0.84237952 |
| 72 | MP0001485_abnormal_pinna_reflex | 0.84210782 |
| 73 | MP0003950_abnormal_plasma_membrane | 0.82614940 |
| 74 | MP0004742_abnormal_vestibular_system | 0.80675855 |
| 75 | MP0003890_abnormal_embryonic-extraembry | 0.79946738 |
| 76 | MP0004036_abnormal_muscle_relaxation | 0.79413438 |
| 77 | MP0003936_abnormal_reproductive_system | 0.79191785 |
| 78 | MP0001879_abnormal_lymphatic_vessel | 0.79069895 |
| 79 | MP0004084_abnormal_cardiac_muscle | 0.78702434 |
| 80 | MP0004510_myositis | 0.76917417 |
| 81 | MP0000653_abnormal_sex_gland | 0.76374171 |
| 82 | MP0006072_abnormal_retinal_apoptosis | 0.75852871 |
| 83 | MP0003866_abnormal_defecation | 0.75587544 |
| 84 | MP0001919_abnormal_reproductive_system | 0.75134168 |
| 85 | MP0002928_abnormal_bile_duct | 0.75079700 |
| 86 | MP0005248_abnormal_Harderian_gland | 0.74920082 |
| 87 | MP0002909_abnormal_adrenal_gland | 0.74337296 |
| 88 | MP0003943_abnormal_hepatobiliary_system | 0.73770379 |
| 89 | MP0003137_abnormal_impulse_conducting | 0.73355125 |
| 90 | MP0003953_abnormal_hormone_level | 0.73049048 |
| 91 | MP0002210_abnormal_sex_determination | 0.71665959 |
| 92 | MP0005389_reproductive_system_phenotype | 0.70175348 |
| 93 | MP0002136_abnormal_kidney_physiology | 0.70131447 |
| 94 | MP0002006_tumorigenesis | 0.70069425 |
| 95 | MP0004019_abnormal_vitamin_homeostasis | 0.69995582 |
| 96 | MP0008872_abnormal_physiological_respon | 0.68875426 |
| 97 | MP0001984_abnormal_olfaction | 0.67125620 |
| 98 | MP0000371_diluted_coat_color | 0.66731686 |
| 99 | MP0009703_decreased_birth_body | 0.66327968 |
| 100 | MP0004924_abnormal_behavior | 0.66055569 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Genetic anticipation (HP:0003743) | 4.48035971 |
| 2 | Gaze-evoked nystagmus (HP:0000640) | 4.27200668 |
| 3 | Pancreatic cysts (HP:0001737) | 4.09394362 |
| 4 | Amelogenesis imperfecta (HP:0000705) | 3.97124167 |
| 5 | Progressive cerebellar ataxia (HP:0002073) | 3.79966249 |
| 6 | Hyperventilation (HP:0002883) | 3.70294395 |
| 7 | Pancreatic fibrosis (HP:0100732) | 3.48068393 |
| 8 | True hermaphroditism (HP:0010459) | 3.39801556 |
| 9 | Abnormality of the nasal septum (HP:0000419) | 3.37995745 |
| 10 | Generalized hypopigmentation of hair (HP:0011358) | 3.33541498 |
| 11 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.33474561 |
| 12 | Broad-based gait (HP:0002136) | 3.12831572 |
| 13 | Chronic hepatic failure (HP:0100626) | 3.11608894 |
| 14 | Hyperglycinuria (HP:0003108) | 2.99883874 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 2.97635668 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.97635668 |
| 17 | Cystic liver disease (HP:0006706) | 2.88209412 |
| 18 | Fair hair (HP:0002286) | 2.88167196 |
| 19 | Nephronophthisis (HP:0000090) | 2.86809844 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.81514364 |
| 21 | Abnormality of the axillary hair (HP:0100134) | 2.78988302 |
| 22 | Abnormality of secondary sexual hair (HP:0009888) | 2.78988302 |
| 23 | Clumsiness (HP:0002312) | 2.75605074 |
| 24 | Decreased circulating renin level (HP:0003351) | 2.70316895 |
| 25 | Abnormality of the renal cortex (HP:0011035) | 2.65142012 |
| 26 | Protruding tongue (HP:0010808) | 2.63003682 |
| 27 | Severe Myopia (HP:0011003) | 2.61606370 |
| 28 | Attenuation of retinal blood vessels (HP:0007843) | 2.61481996 |
| 29 | Hypoplasia of the pons (HP:0012110) | 2.50938037 |
| 30 | Neoplasm of the heart (HP:0100544) | 2.46414310 |
| 31 | Cerebellar dysplasia (HP:0007033) | 2.44198555 |
| 32 | Hypothermia (HP:0002045) | 2.40791680 |
| 33 | Tented upper lip vermilion (HP:0010804) | 2.40176622 |
| 34 | Abnormality of the pons (HP:0007361) | 2.35613946 |
| 35 | Medial flaring of the eyebrow (HP:0010747) | 2.27947202 |
| 36 | Hypoplastic nipples (HP:0002557) | 2.26916486 |
| 37 | Type II lissencephaly (HP:0007260) | 2.20131157 |
| 38 | Abnormality of glycine metabolism (HP:0010895) | 2.14112663 |
| 39 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.14112663 |
| 40 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.11343995 |
| 41 | Absent radius (HP:0003974) | 2.10031634 |
| 42 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.09055379 |
| 43 | Tubular atrophy (HP:0000092) | 2.06488552 |
| 44 | Congenital primary aphakia (HP:0007707) | 2.02859622 |
| 45 | Dysmetric saccades (HP:0000641) | 2.01751343 |
| 46 | Short tibia (HP:0005736) | 2.01312942 |
| 47 | Aplasia involving forearm bones (HP:0009822) | 2.00310522 |
| 48 | Absent forearm bone (HP:0003953) | 2.00310522 |
| 49 | Gait imbalance (HP:0002141) | 1.98301702 |
| 50 | Fibular aplasia (HP:0002990) | 1.97234772 |
| 51 | Gonadotropin excess (HP:0000837) | 1.95893363 |
| 52 | Hypoplasia of the ulna (HP:0003022) | 1.94319089 |
| 53 | Renal tubular acidosis (HP:0001947) | 1.93420431 |
| 54 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.92019211 |
| 55 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.91742786 |
| 56 | Genital tract atresia (HP:0001827) | 1.90899128 |
| 57 | Congenital stationary night blindness (HP:0007642) | 1.90356932 |
| 58 | Postaxial foot polydactyly (HP:0001830) | 1.89130043 |
| 59 | Vaginal atresia (HP:0000148) | 1.88107158 |
| 60 | Hypoplastic labia majora (HP:0000059) | 1.87544091 |
| 61 | Laryngomalacia (HP:0001601) | 1.86905132 |
| 62 | Ketosis (HP:0001946) | 1.86314473 |
| 63 | Ketoacidosis (HP:0001993) | 1.86196841 |
| 64 | Sparse lateral eyebrow (HP:0005338) | 1.84703369 |
| 65 | Poor coordination (HP:0002370) | 1.83856048 |
| 66 | Abolished electroretinogram (ERG) (HP:0000550) | 1.83853177 |
| 67 | Nephrogenic diabetes insipidus (HP:0009806) | 1.82916223 |
| 68 | Stomach cancer (HP:0012126) | 1.82307310 |
| 69 | Abnormality of the ischium (HP:0003174) | 1.81429196 |
| 70 | Bronchomalacia (HP:0002780) | 1.81384454 |
| 71 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.81349852 |
| 72 | Aortic aneurysm (HP:0004942) | 1.81202933 |
| 73 | Anal stenosis (HP:0002025) | 1.80237834 |
| 74 | Abnormality of the fingertips (HP:0001211) | 1.75747736 |
| 75 | Absent/shortened dynein arms (HP:0200106) | 1.74899095 |
| 76 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.74899095 |
| 77 | Abnormality of the labia majora (HP:0012881) | 1.74328628 |
| 78 | Aplasia of the musculature (HP:0100854) | 1.72568792 |
| 79 | Shawl scrotum (HP:0000049) | 1.72070258 |
| 80 | Male pseudohermaphroditism (HP:0000037) | 1.71949142 |
| 81 | Abnormal drinking behavior (HP:0030082) | 1.71787376 |
| 82 | Polydipsia (HP:0001959) | 1.71787376 |
| 83 | Optic nerve hypoplasia (HP:0000609) | 1.71203135 |
| 84 | Prolonged QT interval (HP:0001657) | 1.70354538 |
| 85 | Anencephaly (HP:0002323) | 1.69773546 |
| 86 | Breast hypoplasia (HP:0003187) | 1.69530842 |
| 87 | Absent speech (HP:0001344) | 1.69175191 |
| 88 | Renal cortical cysts (HP:0000803) | 1.68986726 |
| 89 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.66563670 |
| 90 | Aortic regurgitation (HP:0001659) | 1.66184903 |
| 91 | Furrowed tongue (HP:0000221) | 1.65157394 |
| 92 | Tubulointerstitial nephritis (HP:0001970) | 1.64690610 |
| 93 | Widely spaced teeth (HP:0000687) | 1.64179198 |
| 94 | Astigmatism (HP:0000483) | 1.64082491 |
| 95 | Postaxial hand polydactyly (HP:0001162) | 1.63822144 |
| 96 | Depressed nasal tip (HP:0000437) | 1.63667234 |
| 97 | Lip pit (HP:0100267) | 1.63552335 |
| 98 | Congenital hepatic fibrosis (HP:0002612) | 1.63139893 |
| 99 | Keratoconus (HP:0000563) | 1.60633554 |
| 100 | Increased corneal curvature (HP:0100692) | 1.60633554 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | AKT3 | 7.85080000 |
| 2 | FRK | 6.70901007 |
| 3 | TAOK3 | 2.88069921 |
| 4 | BMPR1B | 2.65639492 |
| 5 | STK38L | 2.43966980 |
| 6 | CAMK1D | 2.26542369 |
| 7 | SGK2 | 2.10634307 |
| 8 | ACVR1B | 2.08751167 |
| 9 | TNK2 | 1.96353237 |
| 10 | MYLK | 1.92489279 |
| 11 | DAPK2 | 1.91380229 |
| 12 | CAMK1G | 1.86360883 |
| 13 | WNK4 | 1.72337624 |
| 14 | EEF2K | 1.69374524 |
| 15 | LATS1 | 1.68906029 |
| 16 | WNK3 | 1.56051157 |
| 17 | MAP3K4 | 1.49799892 |
| 18 | MAPK13 | 1.49316232 |
| 19 | SGK223 | 1.48122853 |
| 20 | SGK494 | 1.48122853 |
| 21 | MAPKAPK3 | 1.45864962 |
| 22 | MKNK2 | 1.44294202 |
| 23 | STK38 | 1.43348497 |
| 24 | BRSK2 | 1.34558349 |
| 25 | INSRR | 1.34238216 |
| 26 | STK39 | 1.32043410 |
| 27 | NUAK1 | 1.29810061 |
| 28 | NLK | 1.18843810 |
| 29 | DMPK | 1.15076847 |
| 30 | PIK3CG | 1.12664549 |
| 31 | SGK3 | 1.12601582 |
| 32 | EPHA3 | 1.11890484 |
| 33 | ADRBK2 | 1.05092262 |
| 34 | OXSR1 | 1.03510991 |
| 35 | PRKAA2 | 1.01457191 |
| 36 | MAP4K2 | 1.00328929 |
| 37 | NTRK3 | 0.98064476 |
| 38 | GRK1 | 0.95275118 |
| 39 | ERBB2 | 0.90642343 |
| 40 | ZAK | 0.85958820 |
| 41 | TRPM7 | 0.85441939 |
| 42 | STK3 | 0.81045663 |
| 43 | PRKAA1 | 0.76197888 |
| 44 | MARK2 | 0.71911835 |
| 45 | PIK3CA | 0.71247980 |
| 46 | MUSK | 0.68680963 |
| 47 | CDC42BPA | 0.67973369 |
| 48 | OBSCN | 0.66437446 |
| 49 | PRKD3 | 0.65683427 |
| 50 | PKN2 | 0.60287431 |
| 51 | MAP3K7 | 0.57071026 |
| 52 | MAP2K6 | 0.55886596 |
| 53 | SGK1 | 0.54066103 |
| 54 | TEC | 0.53785087 |
| 55 | FER | 0.53663942 |
| 56 | PRKCE | 0.53310585 |
| 57 | TNIK | 0.52917148 |
| 58 | CHUK | 0.51832787 |
| 59 | TXK | 0.51474658 |
| 60 | MELK | 0.51005718 |
| 61 | CDK12 | 0.50019603 |
| 62 | WNK1 | 0.49952775 |
| 63 | MTOR | 0.49415610 |
| 64 | TGFBR1 | 0.48709493 |
| 65 | BRD4 | 0.48055177 |
| 66 | CAMK1 | 0.45537555 |
| 67 | PAK3 | 0.44818123 |
| 68 | EIF2AK3 | 0.44423605 |
| 69 | MKNK1 | 0.42493792 |
| 70 | ADRBK1 | 0.40701780 |
| 71 | MAPKAPK5 | 0.39091168 |
| 72 | NEK6 | 0.37598788 |
| 73 | PLK4 | 0.36965852 |
| 74 | BCR | 0.36277313 |
| 75 | ERBB3 | 0.36169110 |
| 76 | MARK1 | 0.35380733 |
| 77 | PAK2 | 0.35126074 |
| 78 | PTK2B | 0.33399967 |
| 79 | CSNK1A1L | 0.33026559 |
| 80 | GSK3B | 0.32529670 |
| 81 | KDR | 0.32315554 |
| 82 | MAP2K7 | 0.31967241 |
| 83 | FGFR2 | 0.30942055 |
| 84 | RPS6KA3 | 0.30253540 |
| 85 | MAPK1 | 0.29811058 |
| 86 | DAPK1 | 0.29678977 |
| 87 | AKT1 | 0.29207906 |
| 88 | PRKACA | 0.29041299 |
| 89 | MAPK8 | 0.28414806 |
| 90 | MAPK15 | 0.28171580 |
| 91 | GRK7 | 0.26795261 |
| 92 | RPS6KA5 | 0.26537649 |
| 93 | CSNK1D | 0.26533432 |
| 94 | PKN1 | 0.26353111 |
| 95 | TLK1 | 0.26217182 |
| 96 | GSK3A | 0.25837047 |
| 97 | ROCK1 | 0.25818617 |
| 98 | PINK1 | 0.25081977 |
| 99 | CASK | 0.24325459 |
| 100 | PRKACB | 0.24317862 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ABC transporters_Homo sapiens_hsa02010 | 3.38242870 |
| 2 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.24944778 |
| 3 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.59128871 |
| 4 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.30154409 |
| 5 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.29153341 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.28271275 |
| 7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.26028891 |
| 8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.08461024 |
| 9 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.96787979 |
| 10 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.96332172 |
| 11 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.88613544 |
| 12 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.78862319 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.75364266 |
| 14 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.72576650 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.68510458 |
| 16 | Lysine degradation_Homo sapiens_hsa00310 | 1.67777414 |
| 17 | Mineral absorption_Homo sapiens_hsa04978 | 1.66861384 |
| 18 | Bile secretion_Homo sapiens_hsa04976 | 1.60307057 |
| 19 | Histidine metabolism_Homo sapiens_hsa00340 | 1.57926595 |
| 20 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.53888458 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.51285378 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.47961970 |
| 23 | Circadian rhythm_Homo sapiens_hsa04710 | 1.46301578 |
| 24 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.44814280 |
| 25 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.44676723 |
| 26 | Retinol metabolism_Homo sapiens_hsa00830 | 1.42693869 |
| 27 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.42689622 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.42529992 |
| 29 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.42438064 |
| 30 | Nicotine addiction_Homo sapiens_hsa05033 | 1.39063239 |
| 31 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.36907785 |
| 32 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.24962610 |
| 33 | Taste transduction_Homo sapiens_hsa04742 | 1.24901590 |
| 34 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.23536246 |
| 35 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.23272279 |
| 36 | Prostate cancer_Homo sapiens_hsa05215 | 1.22726806 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.18577317 |
| 38 | Salivary secretion_Homo sapiens_hsa04970 | 1.17595284 |
| 39 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.03054493 |
| 40 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.02277693 |
| 41 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.99474972 |
| 42 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.99355622 |
| 43 | Insulin secretion_Homo sapiens_hsa04911 | 0.97774041 |
| 44 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.95854003 |
| 45 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.95169671 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.93810853 |
| 47 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.92614677 |
| 48 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.89741670 |
| 49 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.89716230 |
| 50 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.89075478 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85916954 |
| 52 | Morphine addiction_Homo sapiens_hsa05032 | 0.84529096 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.83577861 |
| 54 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.81196549 |
| 55 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.78124078 |
| 56 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.77716664 |
| 57 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.77133871 |
| 58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.76069335 |
| 59 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.76009760 |
| 60 | Circadian entrainment_Homo sapiens_hsa04713 | 0.75430377 |
| 61 | RNA polymerase_Homo sapiens_hsa03020 | 0.74811820 |
| 62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.74494927 |
| 63 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.74127945 |
| 64 | Insulin resistance_Homo sapiens_hsa04931 | 0.73174350 |
| 65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.71841131 |
| 66 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.71587005 |
| 67 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.68744718 |
| 68 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.67658195 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.66832354 |
| 70 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.66281159 |
| 71 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.66263562 |
| 72 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.65744891 |
| 73 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.64876578 |
| 74 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.62590148 |
| 75 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62486221 |
| 76 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.61354048 |
| 77 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.60462934 |
| 78 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.58188716 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.57744577 |
| 80 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.57703096 |
| 81 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.55824259 |
| 82 | Cocaine addiction_Homo sapiens_hsa05030 | 0.55728892 |
| 83 | Long-term depression_Homo sapiens_hsa04730 | 0.55547711 |
| 84 | Purine metabolism_Homo sapiens_hsa00230 | 0.55311157 |
| 85 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.54772858 |
| 86 | Tight junction_Homo sapiens_hsa04530 | 0.52046250 |
| 87 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51872627 |
| 88 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.51598208 |
| 89 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.50073748 |
| 90 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48961776 |
| 91 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.48744379 |
| 92 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47405653 |
| 93 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.45651638 |
| 94 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.45400283 |
| 95 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.44994728 |
| 96 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.43866978 |
| 97 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.42977246 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42285762 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42091580 |
| 100 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.40850733 |

