

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | fat-soluble vitamin catabolic process (GO:0042363) | 9.43997816 |
| 2 | vitamin catabolic process (GO:0009111) | 9.43997816 |
| 3 | mature B cell differentiation involved in immune response (GO:0002313) | 8.90361193 |
| 4 | regulation of female receptivity (GO:0045924) | 8.43577384 |
| 5 | skeletal muscle tissue regeneration (GO:0043403) | 7.94398409 |
| 6 | female mating behavior (GO:0060180) | 7.34108797 |
| 7 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 7.25599379 |
| 8 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 7.17926943 |
| 9 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 6.32992354 |
| 10 | mature B cell differentiation (GO:0002335) | 6.24256964 |
| 11 | DNA deamination (GO:0045006) | 6.05039753 |
| 12 | morphogenesis of an endothelium (GO:0003159) | 5.70249985 |
| 13 | endothelial tube morphogenesis (GO:0061154) | 5.70249985 |
| 14 | synaptic transmission, dopaminergic (GO:0001963) | 5.59002938 |
| 15 | detection of light stimulus involved in visual perception (GO:0050908) | 5.42496308 |
| 16 | detection of light stimulus involved in sensory perception (GO:0050962) | 5.42496308 |
| 17 | negative regulation of oxidoreductase activity (GO:0051354) | 5.33900198 |
| 18 | lipoxygenase pathway (GO:0019372) | 5.32666772 |
| 19 | protein targeting to vacuole (GO:0006623) | 4.98613543 |
| 20 | protein targeting to lysosome (GO:0006622) | 4.98613543 |
| 21 | establishment of protein localization to vacuole (GO:0072666) | 4.98613543 |
| 22 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 4.97134514 |
| 23 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 4.90150193 |
| 24 | cellular glucuronidation (GO:0052695) | 4.87231536 |
| 25 | polarized epithelial cell differentiation (GO:0030859) | 4.66223502 |
| 26 | coenzyme catabolic process (GO:0009109) | 4.61257815 |
| 27 | long term synaptic depression (GO:0060292) | 4.60830868 |
| 28 | uronic acid metabolic process (GO:0006063) | 4.57432801 |
| 29 | glucuronate metabolic process (GO:0019585) | 4.57432801 |
| 30 | pantothenate metabolic process (GO:0015939) | 4.56199510 |
| 31 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.44853555 |
| 32 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.40122349 |
| 33 | embryonic heart tube development (GO:0035050) | 4.34027368 |
| 34 | GTP biosynthetic process (GO:0006183) | 4.29446175 |
| 35 | glycosphingolipid biosynthetic process (GO:0006688) | 4.13989411 |
| 36 | lymphangiogenesis (GO:0001946) | 3.98219202 |
| 37 | collecting duct development (GO:0072044) | 3.97889075 |
| 38 | regulation of sensory perception (GO:0051931) | 3.96510064 |
| 39 | regulation of sensory perception of pain (GO:0051930) | 3.96510064 |
| 40 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.96094907 |
| 41 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.95520181 |
| 42 | ATP synthesis coupled proton transport (GO:0015986) | 3.95520181 |
| 43 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.88923171 |
| 44 | protein localization to lysosome (GO:0061462) | 3.87788902 |
| 45 | protein localization to vacuole (GO:0072665) | 3.87788902 |
| 46 | regulation of germinal center formation (GO:0002634) | 3.84507176 |
| 47 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.84408665 |
| 48 | UTP biosynthetic process (GO:0006228) | 3.66633033 |
| 49 | neuronal action potential (GO:0019228) | 3.55617312 |
| 50 | transmission of nerve impulse (GO:0019226) | 3.48255792 |
| 51 | positive regulation of macrophage differentiation (GO:0045651) | 3.44212680 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.42864696 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.42864696 |
| 54 | negative regulation of monooxygenase activity (GO:0032769) | 3.41896203 |
| 55 | protein polyglutamylation (GO:0018095) | 3.38612170 |
| 56 | positive regulation of phosphatase activity (GO:0010922) | 3.31346585 |
| 57 | positive regulation of chemokine secretion (GO:0090197) | 3.28569998 |
| 58 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.28358647 |
| 59 | UTP metabolic process (GO:0046051) | 3.17832029 |
| 60 | primary amino compound metabolic process (GO:1901160) | 3.16137400 |
| 61 | sleep (GO:0030431) | 3.15419031 |
| 62 | L-fucose catabolic process (GO:0042355) | 3.15378851 |
| 63 | fucose catabolic process (GO:0019317) | 3.15378851 |
| 64 | L-fucose metabolic process (GO:0042354) | 3.15378851 |
| 65 | B cell activation involved in immune response (GO:0002312) | 3.11279684 |
| 66 | leukocyte tethering or rolling (GO:0050901) | 3.10464076 |
| 67 | endothelial cell development (GO:0001885) | 3.10263099 |
| 68 | pericardium development (GO:0060039) | 3.09853201 |
| 69 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.08218597 |
| 70 | retina homeostasis (GO:0001895) | 3.08102053 |
| 71 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.06281508 |
| 72 | positive regulation of T cell migration (GO:2000406) | 3.05500079 |
| 73 | basic amino acid transport (GO:0015802) | 3.03427487 |
| 74 | regulation of calcium-mediated signaling (GO:0050848) | 3.01482085 |
| 75 | regulation of interleukin-8 secretion (GO:2000482) | 2.98786904 |
| 76 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 2.97871059 |
| 77 | adenosine metabolic process (GO:0046085) | 2.93338987 |
| 78 | regulation of chemokine secretion (GO:0090196) | 2.92899932 |
| 79 | regulation of macrophage chemotaxis (GO:0010758) | 2.89993120 |
| 80 | protein localization to cilium (GO:0061512) | 2.88424690 |
| 81 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 2.88361210 |
| 82 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.87567834 |
| 83 | zinc ion homeostasis (GO:0055069) | 2.77427969 |
| 84 | CTP metabolic process (GO:0046036) | 2.76316421 |
| 85 | CTP biosynthetic process (GO:0006241) | 2.76316421 |
| 86 | regulation of megakaryocyte differentiation (GO:0045652) | 2.76210029 |
| 87 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.74470090 |
| 88 | regulation of glomerulus development (GO:0090192) | 2.73733069 |
| 89 | regulation of mesoderm development (GO:2000380) | 2.73410800 |
| 90 | response to gravity (GO:0009629) | 2.73165206 |
| 91 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.72498410 |
| 92 | tissue regeneration (GO:0042246) | 2.72494556 |
| 93 | cellular response to dsRNA (GO:0071359) | 2.71561193 |
| 94 | activation of adenylate cyclase activity (GO:0007190) | 2.70802840 |
| 95 | multicellular organismal reproductive behavior (GO:0033057) | 2.68084579 |
| 96 | regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) | 2.66902698 |
| 97 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.66654186 |
| 98 | DNA dealkylation (GO:0035510) | 2.66030283 |
| 99 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.65093891 |
| 100 | sequestering of actin monomers (GO:0042989) | 2.63975326 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 4.29020444 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.05039745 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.65279476 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.30555438 |
| 5 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.27209518 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.07639029 |
| 7 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 3.03522148 |
| 8 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.00221832 |
| 9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.84741064 |
| 10 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.81682302 |
| 11 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.81682302 |
| 12 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.81682302 |
| 13 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.46925963 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.37509579 |
| 15 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 2.35235309 |
| 16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.26131524 |
| 17 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.25553225 |
| 18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.96548455 |
| 19 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.92948352 |
| 20 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.92919098 |
| 21 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.85825073 |
| 22 | VDR_22108803_ChIP-Seq_LS180_Human | 1.85821843 |
| 23 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.84109833 |
| 24 | NCOR_22424771_ChIP-Seq_293T_Human | 1.78666308 |
| 25 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.72098815 |
| 26 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.65866733 |
| 27 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63448032 |
| 28 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.61615725 |
| 29 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.61491501 |
| 30 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.58912619 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.57932203 |
| 32 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.56153132 |
| 33 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.55078303 |
| 34 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.54066699 |
| 35 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.53909467 |
| 36 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.51893777 |
| 37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.49383486 |
| 38 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.48742421 |
| 39 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.45137145 |
| 40 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.43732819 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.43682319 |
| 42 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.43321028 |
| 43 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.42052864 |
| 44 | EWS_26573619_Chip-Seq_HEK293_Human | 1.41211872 |
| 45 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.39266534 |
| 46 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.37399105 |
| 47 | P68_20966046_ChIP-Seq_HELA_Human | 1.35731696 |
| 48 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.34695964 |
| 49 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.34237418 |
| 50 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.33665874 |
| 51 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.31577348 |
| 52 | SOX2_21211035_ChIP-Seq_LN229_Human | 1.31420484 |
| 53 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.30556339 |
| 54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.30358411 |
| 55 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.28523674 |
| 56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.26951841 |
| 57 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.26495441 |
| 58 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.24698503 |
| 59 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.24651559 |
| 60 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.24520526 |
| 61 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.23530001 |
| 62 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.23069054 |
| 63 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.22083410 |
| 64 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.21582027 |
| 65 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.20633829 |
| 66 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.18594949 |
| 67 | ERA_21632823_ChIP-Seq_H3396_Human | 1.18499492 |
| 68 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.18325216 |
| 69 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.17794206 |
| 70 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.14858654 |
| 71 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13774389 |
| 72 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.13041295 |
| 73 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.10254623 |
| 74 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.10088612 |
| 75 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.09121569 |
| 76 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.07796203 |
| 77 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.07334273 |
| 78 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07061941 |
| 79 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.05358748 |
| 80 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.04979340 |
| 81 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.04710611 |
| 82 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03919278 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.03901072 |
| 84 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.02064874 |
| 85 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.00096384 |
| 86 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96674489 |
| 87 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94119233 |
| 88 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93858309 |
| 89 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.93853822 |
| 90 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.93515708 |
| 91 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91898644 |
| 92 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91898644 |
| 93 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.90408615 |
| 94 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90241610 |
| 95 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.90080708 |
| 96 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.90024445 |
| 97 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.90024445 |
| 98 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.89953181 |
| 99 | MYB_26560356_Chip-Seq_TH2_Human | 0.89279661 |
| 100 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.88550516 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002653_abnormal_ependyma_morphology | 8.64649657 |
| 2 | MP0002736_abnormal_nociception_after | 6.04594800 |
| 3 | MP0001968_abnormal_touch/_nociception | 4.68061346 |
| 4 | MP0005360_urolithiasis | 4.67464826 |
| 5 | MP0005409_darkened_coat_color | 4.60636254 |
| 6 | MP0005083_abnormal_biliary_tract | 3.61560633 |
| 7 | MP0003172_abnormal_lysosome_physiology | 3.57121172 |
| 8 | MP0009840_abnormal_foam_cell | 3.12071035 |
| 9 | MP0000678_abnormal_parathyroid_gland | 2.74224770 |
| 10 | MP0006276_abnormal_autonomic_nervous | 2.65679061 |
| 11 | MP0001873_stomach_inflammation | 2.63484138 |
| 12 | MP0002909_abnormal_adrenal_gland | 2.59506949 |
| 13 | MP0009697_abnormal_copulation | 2.43104144 |
| 14 | MP0005671_abnormal_response_to | 2.33119804 |
| 15 | MP0002734_abnormal_mechanical_nocicepti | 2.07199246 |
| 16 | MP0003724_increased_susceptibility_to | 1.94457104 |
| 17 | MP0002277_abnormal_respiratory_mucosa | 1.88338418 |
| 18 | MP0005646_abnormal_pituitary_gland | 1.80636082 |
| 19 | MP0008789_abnormal_olfactory_epithelium | 1.69173024 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.66631108 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 1.62372998 |
| 22 | MP0003950_abnormal_plasma_membrane | 1.60181060 |
| 23 | MP0003646_muscle_fatigue | 1.52262056 |
| 24 | MP0002822_catalepsy | 1.46918517 |
| 25 | MP0002933_joint_inflammation | 1.38531775 |
| 26 | MP0001879_abnormal_lymphatic_vessel | 1.31651879 |
| 27 | MP0002928_abnormal_bile_duct | 1.22491489 |
| 28 | MP0008872_abnormal_physiological_respon | 1.20159662 |
| 29 | MP0004742_abnormal_vestibular_system | 1.17070842 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.09538683 |
| 31 | MP0000613_abnormal_salivary_gland | 1.06625854 |
| 32 | MP0001970_abnormal_pain_threshold | 1.04067486 |
| 33 | MP0001502_abnormal_circadian_rhythm | 1.02447935 |
| 34 | MP0000537_abnormal_urethra_morphology | 1.00146444 |
| 35 | MP0005499_abnormal_olfactory_system | 0.98323009 |
| 36 | MP0005394_taste/olfaction_phenotype | 0.98323009 |
| 37 | MP0004381_abnormal_hair_follicle | 0.98133036 |
| 38 | MP0009053_abnormal_anal_canal | 0.97876200 |
| 39 | MP0000049_abnormal_middle_ear | 0.96956060 |
| 40 | MP0002102_abnormal_ear_morphology | 0.96301188 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 0.93920632 |
| 42 | MP0005645_abnormal_hypothalamus_physiol | 0.92366099 |
| 43 | MP0002282_abnormal_trachea_morphology | 0.92116504 |
| 44 | MP0005367_renal/urinary_system_phenotyp | 0.90615065 |
| 45 | MP0000516_abnormal_urinary_system | 0.90615065 |
| 46 | MP0002127_abnormal_cardiovascular_syste | 0.90181247 |
| 47 | MP0009384_cardiac_valve_regurgitation | 0.90009287 |
| 48 | MP0000534_abnormal_ureter_morphology | 0.88318107 |
| 49 | MP0000538_abnormal_urinary_bladder | 0.87478272 |
| 50 | MP0003938_abnormal_ear_development | 0.85736042 |
| 51 | MP0002735_abnormal_chemical_nociception | 0.85716257 |
| 52 | MP0005000_abnormal_immune_tolerance | 0.84338152 |
| 53 | MP0006292_abnormal_olfactory_placode | 0.82251537 |
| 54 | MP0001800_abnormal_humoral_immune | 0.81901430 |
| 55 | MP0003718_maternal_effect | 0.78473636 |
| 56 | MP0002249_abnormal_larynx_morphology | 0.77350516 |
| 57 | MP0002098_abnormal_vibrissa_morphology | 0.75913135 |
| 58 | MP0003119_abnormal_digestive_system | 0.74821619 |
| 59 | MP0000465_gastrointestinal_hemorrhage | 0.73266324 |
| 60 | MP0001984_abnormal_olfaction | 0.72294814 |
| 61 | MP0001529_abnormal_vocalization | 0.71838939 |
| 62 | MP0001835_abnormal_antigen_presentation | 0.70075323 |
| 63 | MP0005253_abnormal_eye_physiology | 0.69159456 |
| 64 | MP0002723_abnormal_immune_serum | 0.65492041 |
| 65 | MP0010771_integument_phenotype | 0.64278884 |
| 66 | MP0003763_abnormal_thymus_physiology | 0.62968034 |
| 67 | MP0002160_abnormal_reproductive_system | 0.61244651 |
| 68 | MP0001819_abnormal_immune_cell | 0.60734583 |
| 69 | MP0002420_abnormal_adaptive_immunity | 0.59750368 |
| 70 | MP0002166_altered_tumor_susceptibility | 0.59376620 |
| 71 | MP0009764_decreased_sensitivity_to | 0.57606101 |
| 72 | MP0000230_abnormal_systemic_arterial | 0.57438483 |
| 73 | MP0000026_abnormal_inner_ear | 0.57046271 |
| 74 | MP0004085_abnormal_heartbeat | 0.56978244 |
| 75 | MP0001963_abnormal_hearing_physiology | 0.56268578 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.55578100 |
| 77 | MP0001919_abnormal_reproductive_system | 0.55091184 |
| 78 | MP0009785_altered_susceptibility_to | 0.54641298 |
| 79 | MP0001533_abnormal_skeleton_physiology | 0.54525624 |
| 80 | MP0002405_respiratory_system_inflammati | 0.54373802 |
| 81 | MP0009780_abnormal_chondrocyte_physiolo | 0.52293160 |
| 82 | MP0000249_abnormal_blood_vessel | 0.49949155 |
| 83 | MP0000467_abnormal_esophagus_morphology | 0.49932106 |
| 84 | MP0000383_abnormal_hair_follicle | 0.49729580 |
| 85 | MP0003195_calcinosis | 0.48329971 |
| 86 | MP0000470_abnormal_stomach_morphology | 0.47550287 |
| 87 | MP0005389_reproductive_system_phenotype | 0.47317400 |
| 88 | MP0002272_abnormal_nervous_system | 0.47136967 |
| 89 | MP0002138_abnormal_hepatobiliary_system | 0.46664748 |
| 90 | MP0003879_abnormal_hair_cell | 0.46350577 |
| 91 | MP0002419_abnormal_innate_immunity | 0.46048566 |
| 92 | MP0005025_abnormal_response_to | 0.45603845 |
| 93 | MP0004036_abnormal_muscle_relaxation | 0.45589936 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.45448333 |
| 95 | MP0001243_abnormal_dermal_layer | 0.44962446 |
| 96 | MP0000647_abnormal_sebaceous_gland | 0.44730438 |
| 97 | MP0002733_abnormal_thermal_nociception | 0.43999290 |
| 98 | MP0005377_hearing/vestibular/ear_phenot | 0.43504593 |
| 99 | MP0003878_abnormal_ear_physiology | 0.43504593 |
| 100 | MP0002896_abnormal_bone_mineralization | 0.43502396 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.21971989 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 6.21971989 |
| 3 | Dysautonomia (HP:0002459) | 5.92342782 |
| 4 | Failure to thrive in infancy (HP:0001531) | 5.54738782 |
| 5 | Abnormality of cochlea (HP:0000375) | 5.49153546 |
| 6 | Poor head control (HP:0002421) | 5.29407221 |
| 7 | Abolished electroretinogram (ERG) (HP:0000550) | 5.05469739 |
| 8 | Decreased central vision (HP:0007663) | 4.81383409 |
| 9 | Keratoconjunctivitis sicca (HP:0001097) | 4.65712513 |
| 10 | Keratoconjunctivitis (HP:0001096) | 4.47982521 |
| 11 | Tinnitus (HP:0000360) | 4.46036481 |
| 12 | Absent phalangeal crease (HP:0006109) | 4.35048110 |
| 13 | Bony spicule pigmentary retinopathy (HP:0007737) | 4.25915315 |
| 14 | Morphological abnormality of the inner ear (HP:0011390) | 4.25496471 |
| 15 | Constricted visual fields (HP:0001133) | 4.18361537 |
| 16 | Lymphangioma (HP:0100764) | 4.17306129 |
| 17 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.96452050 |
| 18 | Attenuation of retinal blood vessels (HP:0007843) | 3.96344709 |
| 19 | Generalized aminoaciduria (HP:0002909) | 3.92917103 |
| 20 | Follicular hyperkeratosis (HP:0007502) | 3.78429078 |
| 21 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.57181733 |
| 22 | Abnormal finger flexion creases (HP:0006143) | 3.51586689 |
| 23 | Round ear (HP:0100830) | 3.49204939 |
| 24 | Cone-rod dystrophy (HP:0000548) | 3.45171307 |
| 25 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.44253150 |
| 26 | Abnormal autonomic nervous system physiology (HP:0012332) | 3.41771292 |
| 27 | Morphological abnormality of the middle ear (HP:0008609) | 3.35121350 |
| 28 | Distal arthrogryposis (HP:0005684) | 3.29882119 |
| 29 | Increased corneal curvature (HP:0100692) | 3.28317353 |
| 30 | Keratoconus (HP:0000563) | 3.28317353 |
| 31 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.26171491 |
| 32 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.26171491 |
| 33 | Ulnar deviation of the wrist (HP:0003049) | 3.24518723 |
| 34 | Abnormality of the costochondral junction (HP:0000919) | 2.95862450 |
| 35 | Nonimmune hydrops fetalis (HP:0001790) | 2.90337028 |
| 36 | Progressive microcephaly (HP:0000253) | 2.83596542 |
| 37 | Abnormal ciliary motility (HP:0012262) | 2.77195332 |
| 38 | Chest pain (HP:0100749) | 2.66498936 |
| 39 | Calcaneovalgus deformity (HP:0001848) | 2.65688809 |
| 40 | Abnormality of pain sensation (HP:0010832) | 2.63086113 |
| 41 | Impaired pain sensation (HP:0007328) | 2.63086113 |
| 42 | Pustule (HP:0200039) | 2.52707809 |
| 43 | B lymphocytopenia (HP:0010976) | 2.51159906 |
| 44 | Recurrent sinusitis (HP:0011108) | 2.48390108 |
| 45 | Keratitis (HP:0000491) | 2.47174716 |
| 46 | Deformed tarsal bones (HP:0008119) | 2.39398733 |
| 47 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.36610911 |
| 48 | IgG deficiency (HP:0004315) | 2.35155309 |
| 49 | Opisthotonus (HP:0002179) | 2.34118769 |
| 50 | J-shaped sella turcica (HP:0002680) | 2.33791042 |
| 51 | Stenosis of the external auditory canal (HP:0000402) | 2.31066024 |
| 52 | Poor suck (HP:0002033) | 2.29580797 |
| 53 | Severe combined immunodeficiency (HP:0004430) | 2.28314069 |
| 54 | Mesangial abnormality (HP:0001966) | 2.28206086 |
| 55 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.27494630 |
| 56 | Flat capital femoral epiphysis (HP:0003370) | 2.24675338 |
| 57 | Short tibia (HP:0005736) | 2.21649455 |
| 58 | Abnormality of B cell number (HP:0010975) | 2.21609248 |
| 59 | Absent eyebrow (HP:0002223) | 2.19643349 |
| 60 | Aplastic anemia (HP:0001915) | 2.19528565 |
| 61 | Thyroiditis (HP:0100646) | 2.19190109 |
| 62 | Congenital stationary night blindness (HP:0007642) | 2.18276725 |
| 63 | Hamartoma of the eye (HP:0010568) | 2.16148291 |
| 64 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.09189089 |
| 65 | Hypotrichosis (HP:0001006) | 2.06715876 |
| 66 | Abnormality of the renal collecting system (HP:0004742) | 2.05413772 |
| 67 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.03341309 |
| 68 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.01746781 |
| 69 | Absent eyelashes (HP:0000561) | 1.99357327 |
| 70 | Lip pit (HP:0100267) | 1.95927924 |
| 71 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.94492866 |
| 72 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.94251332 |
| 73 | Abnormality of alanine metabolism (HP:0010916) | 1.94251332 |
| 74 | Hyperalaninemia (HP:0003348) | 1.94251332 |
| 75 | Arterial thrombosis (HP:0004420) | 1.91047723 |
| 76 | Abnormality of the nasal septum (HP:0000419) | 1.87423887 |
| 77 | Hypoplasia of the uterus (HP:0000013) | 1.86828127 |
| 78 | Long nose (HP:0003189) | 1.86367958 |
| 79 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.85917338 |
| 80 | Congenital, generalized hypertrichosis (HP:0004540) | 1.85247420 |
| 81 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.84949998 |
| 82 | Photophobia (HP:0000613) | 1.84049570 |
| 83 | Severe Myopia (HP:0011003) | 1.83545393 |
| 84 | Abnormality of serum amino acid levels (HP:0003112) | 1.82461942 |
| 85 | Vertigo (HP:0002321) | 1.79623112 |
| 86 | Obstructive sleep apnea (HP:0002870) | 1.73338176 |
| 87 | Conjunctival hamartoma (HP:0100780) | 1.73322039 |
| 88 | Abnormality of the peritoneum (HP:0002585) | 1.72783597 |
| 89 | Amaurosis fugax (HP:0100576) | 1.71901110 |
| 90 | Abnormality of the prostate (HP:0008775) | 1.70838336 |
| 91 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.70324779 |
| 92 | Methylmalonic aciduria (HP:0012120) | 1.69584584 |
| 93 | Prostate neoplasm (HP:0100787) | 1.68200131 |
| 94 | Synostosis involving the elbow (HP:0003938) | 1.67432737 |
| 95 | Humeroradial synostosis (HP:0003041) | 1.67432737 |
| 96 | Aortic valve stenosis (HP:0001650) | 1.67264679 |
| 97 | Abnormality of the renal cortex (HP:0011035) | 1.65861145 |
| 98 | Short femoral neck (HP:0100864) | 1.62884248 |
| 99 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.61345451 |
| 100 | Short hallux (HP:0010109) | 1.59578219 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP2K2 | 4.15342522 |
| 2 | NUAK1 | 3.66034411 |
| 3 | TESK2 | 3.62667587 |
| 4 | ZAK | 3.38714741 |
| 5 | TAOK3 | 3.11631116 |
| 6 | VRK2 | 2.93651356 |
| 7 | GRK1 | 2.66405666 |
| 8 | TXK | 2.66379135 |
| 9 | KDR | 2.64129853 |
| 10 | MAP4K2 | 2.38538482 |
| 11 | TLK1 | 2.32266837 |
| 12 | TESK1 | 2.05366082 |
| 13 | CDK4 | 1.91938664 |
| 14 | FRK | 1.90538454 |
| 15 | CSNK1G3 | 1.89348230 |
| 16 | MUSK | 1.88021010 |
| 17 | DAPK1 | 1.77978023 |
| 18 | BCKDK | 1.72437242 |
| 19 | STK38 | 1.68320172 |
| 20 | CSNK1A1L | 1.58604175 |
| 21 | CSNK1G2 | 1.50539961 |
| 22 | MAP2K1 | 1.46983396 |
| 23 | PIK3CA | 1.39723766 |
| 24 | VRK1 | 1.37114498 |
| 25 | MAP3K12 | 1.34952577 |
| 26 | GRK6 | 1.34387566 |
| 27 | MYLK | 1.33593774 |
| 28 | TIE1 | 1.31808629 |
| 29 | CSNK1G1 | 1.30678590 |
| 30 | SCYL2 | 1.27649589 |
| 31 | ZAP70 | 1.26433527 |
| 32 | PAK4 | 1.24346475 |
| 33 | INSRR | 1.17899211 |
| 34 | IKBKB | 1.10022193 |
| 35 | BMPR1B | 1.05217650 |
| 36 | ERBB2 | 1.03621954 |
| 37 | ADRBK2 | 1.03071756 |
| 38 | MAPKAPK3 | 1.01939424 |
| 39 | CCNB1 | 1.00493750 |
| 40 | CHEK2 | 0.99464527 |
| 41 | MAPKAPK5 | 0.97214916 |
| 42 | TAF1 | 0.96072212 |
| 43 | MAP4K1 | 0.95422369 |
| 44 | LMTK2 | 0.94731200 |
| 45 | LIMK1 | 0.94281479 |
| 46 | EPHA2 | 0.85999072 |
| 47 | CAMKK2 | 0.83902318 |
| 48 | MAP2K6 | 0.83690664 |
| 49 | IKBKE | 0.83306379 |
| 50 | TNK2 | 0.81849373 |
| 51 | MST4 | 0.80328274 |
| 52 | AURKA | 0.78414568 |
| 53 | NME2 | 0.77812667 |
| 54 | PLK2 | 0.77021193 |
| 55 | CDK19 | 0.73743348 |
| 56 | GRK5 | 0.73508108 |
| 57 | SYK | 0.72425120 |
| 58 | PHKG2 | 0.72289152 |
| 59 | PHKG1 | 0.72289152 |
| 60 | CHUK | 0.72116648 |
| 61 | PAK6 | 0.67458862 |
| 62 | HIPK2 | 0.67210324 |
| 63 | PTK2 | 0.62983274 |
| 64 | MAPK4 | 0.61174455 |
| 65 | MAPKAPK2 | 0.60269542 |
| 66 | TBK1 | 0.59483860 |
| 67 | SMG1 | 0.58592107 |
| 68 | PTK2B | 0.55879812 |
| 69 | WNK4 | 0.51811058 |
| 70 | CDK8 | 0.50434996 |
| 71 | LCK | 0.50004732 |
| 72 | PRKCI | 0.49764638 |
| 73 | OXSR1 | 0.48423608 |
| 74 | ITK | 0.48058898 |
| 75 | CSNK1A1 | 0.47061334 |
| 76 | OBSCN | 0.46479437 |
| 77 | RPS6KA2 | 0.45882015 |
| 78 | TEC | 0.45593114 |
| 79 | CAMK2B | 0.45194368 |
| 80 | DAPK3 | 0.44575685 |
| 81 | BLK | 0.42938643 |
| 82 | NME1 | 0.41246684 |
| 83 | ILK | 0.38073875 |
| 84 | EIF2AK2 | 0.37675843 |
| 85 | ABL2 | 0.37402749 |
| 86 | KIT | 0.37294129 |
| 87 | ROCK1 | 0.36918251 |
| 88 | RPS6KA5 | 0.35950414 |
| 89 | CSF1R | 0.34838300 |
| 90 | CDK7 | 0.33460428 |
| 91 | PRKCE | 0.32657286 |
| 92 | IGF1R | 0.31994418 |
| 93 | PRKCA | 0.30858373 |
| 94 | BMPR2 | 0.28740828 |
| 95 | ATR | 0.28508398 |
| 96 | ABL1 | 0.28099316 |
| 97 | NEK6 | 0.27030724 |
| 98 | PRKCQ | 0.26776696 |
| 99 | MAPK13 | 0.26186982 |
| 100 | PRKD1 | 0.25378324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.86019166 |
| 2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.77813774 |
| 3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.48768172 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.19512595 |
| 5 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.99971261 |
| 6 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.69850521 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.38972593 |
| 8 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.38896814 |
| 9 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.36345060 |
| 10 | Olfactory transduction_Homo sapiens_hsa04740 | 2.34488154 |
| 11 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 2.34218794 |
| 12 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.33284489 |
| 13 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.27074035 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.20714855 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 2.12310024 |
| 16 | Retinol metabolism_Homo sapiens_hsa00830 | 2.10922605 |
| 17 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 2.10577123 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.93205710 |
| 19 | Sulfur relay system_Homo sapiens_hsa04122 | 1.93167244 |
| 20 | Proteasome_Homo sapiens_hsa03050 | 1.92987490 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.88000317 |
| 22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.86880135 |
| 23 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.82539364 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.81806616 |
| 25 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.50705563 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.48146289 |
| 27 | Histidine metabolism_Homo sapiens_hsa00340 | 1.47565643 |
| 28 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.39739668 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.30263774 |
| 30 | RNA polymerase_Homo sapiens_hsa03020 | 1.29433739 |
| 31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.27205133 |
| 32 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.25644039 |
| 33 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.19035597 |
| 34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.18652223 |
| 35 | Parkinsons disease_Homo sapiens_hsa05012 | 1.13742824 |
| 36 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.12864845 |
| 37 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.12191442 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.08576518 |
| 39 | Viral myocarditis_Homo sapiens_hsa05416 | 1.05720848 |
| 40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05380461 |
| 41 | DNA replication_Homo sapiens_hsa03030 | 1.00918080 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.96733693 |
| 43 | Legionellosis_Homo sapiens_hsa05134 | 0.96587087 |
| 44 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.92969608 |
| 45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.92167446 |
| 46 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.91582337 |
| 47 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.90939922 |
| 48 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.82887862 |
| 49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.81649277 |
| 50 | Alzheimers disease_Homo sapiens_hsa05010 | 0.80795753 |
| 51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.78809277 |
| 52 | Mismatch repair_Homo sapiens_hsa03430 | 0.76219716 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76079977 |
| 54 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.75015278 |
| 55 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.74469181 |
| 56 | ABC transporters_Homo sapiens_hsa02010 | 0.70307465 |
| 57 | Taste transduction_Homo sapiens_hsa04742 | 0.66875682 |
| 58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.66374554 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.63247564 |
| 60 | Lysine degradation_Homo sapiens_hsa00310 | 0.59698538 |
| 61 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.58762113 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.57781154 |
| 63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.53879060 |
| 64 | Purine metabolism_Homo sapiens_hsa00230 | 0.50853227 |
| 65 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.50377756 |
| 66 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.48975021 |
| 67 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.48289914 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.48011042 |
| 69 | Protein export_Homo sapiens_hsa03060 | 0.47843176 |
| 70 | Base excision repair_Homo sapiens_hsa03410 | 0.47712951 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46199622 |
| 72 | Alcoholism_Homo sapiens_hsa05034 | 0.45844441 |
| 73 | RNA degradation_Homo sapiens_hsa03018 | 0.44741099 |
| 74 | Lysosome_Homo sapiens_hsa04142 | 0.43887094 |
| 75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.43345294 |
| 76 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.42091403 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.41841855 |
| 78 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.39562030 |
| 79 | Huntingtons disease_Homo sapiens_hsa05016 | 0.38220402 |
| 80 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.36621634 |
| 81 | Salivary secretion_Homo sapiens_hsa04970 | 0.35516724 |
| 82 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.34757728 |
| 83 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.34662628 |
| 84 | Renin secretion_Homo sapiens_hsa04924 | 0.34488141 |
| 85 | Circadian entrainment_Homo sapiens_hsa04713 | 0.33772326 |
| 86 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.33539679 |
| 87 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32548027 |
| 88 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.32436753 |
| 89 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.30718013 |
| 90 | Salmonella infection_Homo sapiens_hsa05132 | 0.27162574 |
| 91 | Measles_Homo sapiens_hsa05162 | 0.27005317 |
| 92 | Insulin secretion_Homo sapiens_hsa04911 | 0.25177893 |
| 93 | Spliceosome_Homo sapiens_hsa03040 | 0.24190365 |
| 94 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.23940227 |
| 95 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.22854166 |
| 96 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.20609618 |
| 97 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.20010521 |
| 98 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.19660938 |
| 99 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.15365474 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.14718141 |

