

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.22608667 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.94723567 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.94723567 |
| 4 | DNA deamination (GO:0045006) | 5.43179373 |
| 5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.59051751 |
| 6 | cytidine deamination (GO:0009972) | 4.47398304 |
| 7 | cytidine metabolic process (GO:0046087) | 4.47398304 |
| 8 | cytidine catabolic process (GO:0006216) | 4.47398304 |
| 9 | respiratory electron transport chain (GO:0022904) | 4.46929820 |
| 10 | electron transport chain (GO:0022900) | 4.41743640 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.23758286 |
| 12 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.12375816 |
| 13 | proteasome assembly (GO:0043248) | 4.06090106 |
| 14 | positive regulation of protein homodimerization activity (GO:0090073) | 4.01644282 |
| 15 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.95524008 |
| 16 | chaperone-mediated protein transport (GO:0072321) | 3.84140676 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.79232119 |
| 18 | actin nucleation (GO:0045010) | 3.78493713 |
| 19 | protein complex biogenesis (GO:0070271) | 3.76320990 |
| 20 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.75728393 |
| 21 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.71437879 |
| 22 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.70784985 |
| 23 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.65847030 |
| 24 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.64808808 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.61851575 |
| 26 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.61851575 |
| 27 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.61851575 |
| 28 | protein neddylation (GO:0045116) | 3.59677054 |
| 29 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.58611746 |
| 30 | protein-cofactor linkage (GO:0018065) | 3.55148453 |
| 31 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.53884168 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.53884168 |
| 33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.52567806 |
| 34 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.51884033 |
| 35 | ATP biosynthetic process (GO:0006754) | 3.46643134 |
| 36 | regulation of chronic inflammatory response (GO:0002676) | 3.44677817 |
| 37 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.43377572 |
| 38 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.43377572 |
| 39 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.41548821 |
| 40 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.40989041 |
| 41 | negative regulation of ligase activity (GO:0051352) | 3.40989041 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38626517 |
| 43 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.35928313 |
| 44 | hydrogen ion transmembrane transport (GO:1902600) | 3.33358957 |
| 45 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.32770292 |
| 46 | sequestering of actin monomers (GO:0042989) | 3.30569567 |
| 47 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.27375672 |
| 48 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.27375672 |
| 49 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.25084894 |
| 50 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.24757046 |
| 51 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.23943820 |
| 52 | cellular response to interleukin-15 (GO:0071350) | 3.23602461 |
| 53 | platelet dense granule organization (GO:0060155) | 3.22775721 |
| 54 | GPI anchor biosynthetic process (GO:0006506) | 3.20136550 |
| 55 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.19785814 |
| 56 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.19785814 |
| 57 | NADH dehydrogenase complex assembly (GO:0010257) | 3.19785814 |
| 58 | protein maturation by protein folding (GO:0022417) | 3.19536789 |
| 59 | proton transport (GO:0015992) | 3.18954342 |
| 60 | metallo-sulfur cluster assembly (GO:0031163) | 3.17506077 |
| 61 | iron-sulfur cluster assembly (GO:0016226) | 3.17506077 |
| 62 | hydrogen transport (GO:0006818) | 3.12089431 |
| 63 | ubiquinone biosynthetic process (GO:0006744) | 3.08498845 |
| 64 | cytochrome complex assembly (GO:0017004) | 3.06694657 |
| 65 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.05807334 |
| 66 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.05255824 |
| 67 | protein deneddylation (GO:0000338) | 3.02222482 |
| 68 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.02006757 |
| 69 | termination of RNA polymerase III transcription (GO:0006386) | 3.02006757 |
| 70 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.01193559 |
| 71 | negative regulation of mast cell activation (GO:0033004) | 3.00654317 |
| 72 | base-excision repair, AP site formation (GO:0006285) | 2.99852314 |
| 73 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.97431164 |
| 74 | respiratory chain complex IV assembly (GO:0008535) | 2.96683294 |
| 75 | ubiquinone metabolic process (GO:0006743) | 2.95645537 |
| 76 | GPI anchor metabolic process (GO:0006505) | 2.94656742 |
| 77 | pseudouridine synthesis (GO:0001522) | 2.93560177 |
| 78 | negative regulation of heart rate (GO:0010459) | 2.91190234 |
| 79 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.88670034 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.85299319 |
| 81 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.85122695 |
| 82 | response to pheromone (GO:0019236) | 2.82325492 |
| 83 | positive regulation of ligase activity (GO:0051351) | 2.81736561 |
| 84 | cullin deneddylation (GO:0010388) | 2.81082615 |
| 85 | ribosomal small subunit assembly (GO:0000028) | 2.80411680 |
| 86 | maturation of SSU-rRNA (GO:0030490) | 2.78231491 |
| 87 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.76752546 |
| 88 | mannosylation (GO:0097502) | 2.76094277 |
| 89 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.74433224 |
| 90 | regulation of cellular amine metabolic process (GO:0033238) | 2.74087210 |
| 91 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.68913364 |
| 92 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.67547265 |
| 93 | response to interleukin-15 (GO:0070672) | 2.66842175 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.63847943 |
| 95 | regulation of interleukin-8 secretion (GO:2000482) | 2.63806443 |
| 96 | positive regulation of cell cycle arrest (GO:0071158) | 2.63610482 |
| 97 | positive regulation of defense response to virus by host (GO:0002230) | 2.62483967 |
| 98 | regulation of cellular respiration (GO:0043457) | 2.60763844 |
| 99 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.59258442 |
| 100 | regulation of hypersensitivity (GO:0002883) | 2.58928577 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.58458315 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.98504409 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.94533033 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.92735774 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.72319971 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.71696789 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.56670083 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.20270421 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.98216155 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.87389878 |
| 11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.69887401 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.60427262 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.60206792 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.56790402 |
| 15 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.49763633 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.22680779 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.19441617 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.13500297 |
| 19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.10677997 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.10242070 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.09806978 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.09104337 |
| 23 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.98156773 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95754740 |
| 25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.90680068 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.89542560 |
| 27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.74228512 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.73513610 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.73235876 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63965974 |
| 31 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.55053437 |
| 32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.54456298 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.51355160 |
| 34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47460033 |
| 35 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.47385671 |
| 36 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.46554864 |
| 37 | * MYB_26560356_Chip-Seq_TH2_Human | 1.46284051 |
| 38 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45404704 |
| 39 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.43389992 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39857500 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.38568397 |
| 42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.36512766 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32982048 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.32777879 |
| 45 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.32448471 |
| 46 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.28771040 |
| 47 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.28567789 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.27048465 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26237186 |
| 50 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23500881 |
| 51 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.21606144 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.21362212 |
| 53 | AR_20517297_ChIP-Seq_VCAP_Human | 1.19325280 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18046820 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18046820 |
| 56 | NCOR_22424771_ChIP-Seq_293T_Human | 1.15614308 |
| 57 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.14532738 |
| 58 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11545035 |
| 59 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10837947 |
| 60 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.10126200 |
| 61 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09281057 |
| 62 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09159231 |
| 63 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.08740108 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07339397 |
| 65 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.07255572 |
| 66 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05997776 |
| 67 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.05659350 |
| 68 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.05238554 |
| 69 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.03685148 |
| 70 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.03474702 |
| 71 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03187845 |
| 72 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.02574820 |
| 73 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02223127 |
| 74 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.01844893 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01760233 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01760233 |
| 77 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.01493782 |
| 78 | * TAF15_26573619_Chip-Seq_HEK293_Human | 1.01393474 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00609449 |
| 80 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99651591 |
| 81 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.99368226 |
| 82 | EWS_26573619_Chip-Seq_HEK293_Human | 0.99329568 |
| 83 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98811902 |
| 84 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98697370 |
| 85 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98605067 |
| 86 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98383858 |
| 87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98105566 |
| 88 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97980419 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97096539 |
| 90 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96970460 |
| 91 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95340246 |
| 92 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.93513585 |
| 93 | P300_19829295_ChIP-Seq_ESCs_Human | 0.93258868 |
| 94 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.92896617 |
| 95 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.92737684 |
| 96 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.92660902 |
| 97 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.92030801 |
| 98 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91036348 |
| 99 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.90768187 |
| 100 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.90596278 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.52356189 |
| 2 | MP0009785_altered_susceptibility_to | 2.94075958 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 2.82429481 |
| 4 | MP0004147_increased_porphyrin_level | 2.79743633 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.73723531 |
| 6 | MP0005360_urolithiasis | 2.62460657 |
| 7 | MP0000685_abnormal_immune_system | 2.37352635 |
| 8 | MP0009333_abnormal_splenocyte_physiolog | 2.31305144 |
| 9 | MP0003763_abnormal_thymus_physiology | 2.27772003 |
| 10 | MP0001800_abnormal_humoral_immune | 2.26719830 |
| 11 | MP0003724_increased_susceptibility_to | 2.25653556 |
| 12 | MP0003646_muscle_fatigue | 2.12371584 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 2.07906379 |
| 14 | MP0008872_abnormal_physiological_respon | 1.98195318 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 1.97028832 |
| 16 | MP0002102_abnormal_ear_morphology | 1.90345804 |
| 17 | MP0003011_delayed_dark_adaptation | 1.88982368 |
| 18 | MP0005000_abnormal_immune_tolerance | 1.84302024 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 1.76087937 |
| 20 | MP0002723_abnormal_immune_serum | 1.74945138 |
| 21 | MP0002736_abnormal_nociception_after | 1.73050454 |
| 22 | MP0003866_abnormal_defecation | 1.71967533 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.71274694 |
| 24 | MP0005387_immune_system_phenotype | 1.70439857 |
| 25 | MP0001790_abnormal_immune_system | 1.70439857 |
| 26 | MP0002452_abnormal_antigen_presenting | 1.65151010 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.64188150 |
| 28 | MP0005253_abnormal_eye_physiology | 1.63890496 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.63433651 |
| 30 | MP0001819_abnormal_immune_cell | 1.62871886 |
| 31 | MP0003786_premature_aging | 1.60425943 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.60098851 |
| 33 | MP0009764_decreased_sensitivity_to | 1.58893045 |
| 34 | MP0005075_abnormal_melanosome_morpholog | 1.54695319 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.52316027 |
| 36 | MP0001905_abnormal_dopamine_level | 1.46749320 |
| 37 | MP0005025_abnormal_response_to | 1.42584620 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.39428732 |
| 39 | MP0001986_abnormal_taste_sensitivity | 1.39309170 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.39283034 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.38663837 |
| 42 | MP0004142_abnormal_muscle_tone | 1.35745929 |
| 43 | MP0001873_stomach_inflammation | 1.32664600 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.32310540 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.29504693 |
| 46 | MP0006082_CNS_inflammation | 1.27802895 |
| 47 | MP0002006_tumorigenesis | 1.25738994 |
| 48 | MP0002638_abnormal_pupillary_reflex | 1.23802009 |
| 49 | MP0001845_abnormal_inflammatory_respons | 1.22739191 |
| 50 | MP0006036_abnormal_mitochondrial_physio | 1.19847744 |
| 51 | MP0003252_abnormal_bile_duct | 1.19833260 |
| 52 | MP0008995_early_reproductive_senescence | 1.17962815 |
| 53 | MP0005085_abnormal_gallbladder_physiolo | 1.17597253 |
| 54 | MP0006292_abnormal_olfactory_placode | 1.17483185 |
| 55 | MP0000716_abnormal_immune_system | 1.16273286 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.13546429 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 1.13428067 |
| 58 | MP0003878_abnormal_ear_physiology | 1.13428067 |
| 59 | MP0002398_abnormal_bone_marrow | 1.13357818 |
| 60 | MP0002138_abnormal_hepatobiliary_system | 1.09973234 |
| 61 | MP0000372_irregular_coat_pigmentation | 1.09647420 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.08183843 |
| 63 | MP0003718_maternal_effect | 1.07101106 |
| 64 | MP0003436_decreased_susceptibility_to | 1.06777958 |
| 65 | MP0001984_abnormal_olfaction | 1.06303088 |
| 66 | MP0004145_abnormal_muscle_electrophysio | 1.03759525 |
| 67 | MP0002419_abnormal_innate_immunity | 1.01857158 |
| 68 | MP0003638_abnormal_response/metabolism_ | 0.99730412 |
| 69 | MP0002405_respiratory_system_inflammati | 0.99166129 |
| 70 | MP0003806_abnormal_nucleotide_metabolis | 0.97280954 |
| 71 | MP0001764_abnormal_homeostasis | 0.94481023 |
| 72 | MP0008058_abnormal_DNA_repair | 0.94216663 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.92279437 |
| 74 | MP0005636_abnormal_mineral_homeostasis | 0.91327007 |
| 75 | MP0002722_abnormal_immune_system | 0.91218978 |
| 76 | MP0002429_abnormal_blood_cell | 0.91148995 |
| 77 | MP0005410_abnormal_fertilization | 0.90247005 |
| 78 | MP0008469_abnormal_protein_level | 0.89834539 |
| 79 | MP0005167_abnormal_blood-brain_barrier | 0.87462615 |
| 80 | MP0000230_abnormal_systemic_arterial | 0.87256516 |
| 81 | MP0009763_increased_sensitivity_to | 0.87147349 |
| 82 | MP0001533_abnormal_skeleton_physiology | 0.85161136 |
| 83 | MP0002272_abnormal_nervous_system | 0.82074277 |
| 84 | MP0004885_abnormal_endolymph | 0.80693082 |
| 85 | MP0001919_abnormal_reproductive_system | 0.79536163 |
| 86 | MP0002163_abnormal_gland_morphology | 0.78561130 |
| 87 | MP0006276_abnormal_autonomic_nervous | 0.78388200 |
| 88 | MP0005332_abnormal_amino_acid | 0.78044910 |
| 89 | MP0009046_muscle_twitch | 0.75885816 |
| 90 | MP0005367_renal/urinary_system_phenotyp | 0.75862641 |
| 91 | MP0000516_abnormal_urinary_system | 0.75862641 |
| 92 | MP0001853_heart_inflammation | 0.75155985 |
| 93 | MP0004215_abnormal_myocardial_fiber | 0.74510487 |
| 94 | MP0005365_abnormal_bile_salt | 0.73909734 |
| 95 | MP0003137_abnormal_impulse_conducting | 0.72248127 |
| 96 | MP0003075_altered_response_to | 0.72055983 |
| 97 | MP0002837_dystrophic_cardiac_calcinosis | 0.71601524 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.71209718 |
| 99 | MP0000703_abnormal_thymus_morphology | 0.70896851 |
| 100 | MP0004043_abnormal_pH_regulation | 0.69239639 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.38151440 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.23118828 |
| 3 | Increased CSF lactate (HP:0002490) | 4.15110152 |
| 4 | IgG deficiency (HP:0004315) | 3.94705473 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.80354736 |
| 6 | Lipid accumulation in hepatocytes (HP:0006561) | 3.79836083 |
| 7 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.78118248 |
| 8 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.78118248 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.77828328 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.72307176 |
| 11 | Hepatic necrosis (HP:0002605) | 3.57275872 |
| 12 | Acute encephalopathy (HP:0006846) | 3.50318281 |
| 13 | Hypoproteinemia (HP:0003075) | 3.49587787 |
| 14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.43661826 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.43329073 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.38237190 |
| 17 | Aplastic anemia (HP:0001915) | 3.34126949 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 3.20095733 |
| 19 | Congenital stationary night blindness (HP:0007642) | 3.16369846 |
| 20 | Stomatitis (HP:0010280) | 3.09799631 |
| 21 | T lymphocytopenia (HP:0005403) | 3.02065940 |
| 22 | Increased serum lactate (HP:0002151) | 2.99978570 |
| 23 | Abnormality of T cell number (HP:0011839) | 2.98402379 |
| 24 | Abnormality of B cell number (HP:0010975) | 2.94259940 |
| 25 | Abolished electroretinogram (ERG) (HP:0000550) | 2.89864340 |
| 26 | Cerebral edema (HP:0002181) | 2.89554149 |
| 27 | Increased muscle lipid content (HP:0009058) | 2.88761417 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.84723906 |
| 29 | Type II lissencephaly (HP:0007260) | 2.77194108 |
| 30 | Renal cortical cysts (HP:0000803) | 2.71592697 |
| 31 | Pancreatic cysts (HP:0001737) | 2.71451533 |
| 32 | B lymphocytopenia (HP:0010976) | 2.64764872 |
| 33 | Autoimmune hemolytic anemia (HP:0001890) | 2.62195487 |
| 34 | Exertional dyspnea (HP:0002875) | 2.59241562 |
| 35 | Severe combined immunodeficiency (HP:0004430) | 2.59066527 |
| 36 | Lactic acidosis (HP:0003128) | 2.56135598 |
| 37 | Abnormality of the prostate (HP:0008775) | 2.54901767 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.52676432 |
| 39 | Generalized aminoaciduria (HP:0002909) | 2.47784649 |
| 40 | Molar tooth sign on MRI (HP:0002419) | 2.43536220 |
| 41 | Abnormality of midbrain morphology (HP:0002418) | 2.43536220 |
| 42 | Neonatal respiratory distress (HP:0002643) | 2.41475089 |
| 43 | Optic disc pallor (HP:0000543) | 2.39608388 |
| 44 | Respiratory failure (HP:0002878) | 2.34379972 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.31414258 |
| 46 | Retrobulbar optic neuritis (HP:0100654) | 2.30482217 |
| 47 | Optic neuritis (HP:0100653) | 2.30482217 |
| 48 | CNS demyelination (HP:0007305) | 2.29079654 |
| 49 | Increased IgM level (HP:0003496) | 2.27622231 |
| 50 | 3-Methylglutaconic aciduria (HP:0003535) | 2.22527872 |
| 51 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.22112017 |
| 52 | Lethargy (HP:0001254) | 2.21606943 |
| 53 | Exercise intolerance (HP:0003546) | 2.18915108 |
| 54 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.18375079 |
| 55 | Abnormality of T cells (HP:0002843) | 2.17856418 |
| 56 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.17154666 |
| 57 | Retinal dysplasia (HP:0007973) | 2.10613791 |
| 58 | Glycosuria (HP:0003076) | 2.07250940 |
| 59 | Abnormality of urine glucose concentration (HP:0011016) | 2.07250940 |
| 60 | Pancreatic fibrosis (HP:0100732) | 2.05656900 |
| 61 | Azoospermia (HP:0000027) | 2.04574597 |
| 62 | Nephronophthisis (HP:0000090) | 2.04069860 |
| 63 | Myositis (HP:0100614) | 2.03701590 |
| 64 | Pancytopenia (HP:0001876) | 1.96007172 |
| 65 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.95114974 |
| 66 | Constricted visual fields (HP:0001133) | 1.94389595 |
| 67 | Pendular nystagmus (HP:0012043) | 1.92243017 |
| 68 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.91881461 |
| 69 | Combined immunodeficiency (HP:0005387) | 1.91784994 |
| 70 | Abnormality of renal resorption (HP:0011038) | 1.91391547 |
| 71 | Oral leukoplakia (HP:0002745) | 1.90763074 |
| 72 | Abnormal spermatogenesis (HP:0008669) | 1.90673964 |
| 73 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.87778098 |
| 74 | Thyroiditis (HP:0100646) | 1.87585864 |
| 75 | Increased corneal curvature (HP:0100692) | 1.87507947 |
| 76 | Keratoconus (HP:0000563) | 1.87507947 |
| 77 | Gangrene (HP:0100758) | 1.86754285 |
| 78 | Leukodystrophy (HP:0002415) | 1.86565489 |
| 79 | Pulmonary infiltrates (HP:0002113) | 1.86084609 |
| 80 | Chronic diarrhea (HP:0002028) | 1.85749730 |
| 81 | Orchitis (HP:0100796) | 1.81595479 |
| 82 | Abnormality of the renal medulla (HP:0100957) | 1.81301363 |
| 83 | Prostate neoplasm (HP:0100787) | 1.81155711 |
| 84 | Brittle hair (HP:0002299) | 1.80619591 |
| 85 | Stomach cancer (HP:0012126) | 1.79789155 |
| 86 | True hermaphroditism (HP:0010459) | 1.79188283 |
| 87 | Type I transferrin isoform profile (HP:0003642) | 1.78031789 |
| 88 | Hypoalbuminemia (HP:0003073) | 1.77949413 |
| 89 | Abnormal albumin level (HP:0012116) | 1.77949413 |
| 90 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.76115907 |
| 91 | Sclerocornea (HP:0000647) | 1.74966318 |
| 92 | Abnormality of eosinophils (HP:0001879) | 1.73461218 |
| 93 | Abnormality of the pleura (HP:0002103) | 1.73142326 |
| 94 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.72929513 |
| 95 | Reduced antithrombin III activity (HP:0001976) | 1.72666264 |
| 96 | Progressive microcephaly (HP:0000253) | 1.71678121 |
| 97 | Attenuation of retinal blood vessels (HP:0007843) | 1.70131339 |
| 98 | Hypothermia (HP:0002045) | 1.68841499 |
| 99 | Increased serum pyruvate (HP:0003542) | 1.68404638 |
| 100 | Pancreatitis (HP:0001733) | 1.67841025 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.32970343 |
| 2 | TAOK3 | 3.51590012 |
| 3 | ZAK | 3.44422019 |
| 4 | MAP3K12 | 3.12511835 |
| 5 | KDR | 2.97897397 |
| 6 | SCYL2 | 2.93117760 |
| 7 | GRK1 | 2.84582433 |
| 8 | VRK2 | 2.73894011 |
| 9 | TLK1 | 2.40377338 |
| 10 | TESK1 | 2.20433046 |
| 11 | STK16 | 2.18432425 |
| 12 | ADRBK2 | 1.96085828 |
| 13 | MST4 | 1.95146520 |
| 14 | BUB1 | 1.91264763 |
| 15 | TESK2 | 1.83567376 |
| 16 | BMPR2 | 1.73192433 |
| 17 | MUSK | 1.66758268 |
| 18 | ITK | 1.65089964 |
| 19 | MAP4K2 | 1.60169711 |
| 20 | NME1 | 1.53636327 |
| 21 | MAPKAPK3 | 1.52308681 |
| 22 | MYLK | 1.49570174 |
| 23 | DAPK1 | 1.41382583 |
| 24 | BCKDK | 1.41131504 |
| 25 | VRK1 | 1.38004776 |
| 26 | CDK8 | 1.37922977 |
| 27 | TIE1 | 1.36787178 |
| 28 | TEC | 1.34309236 |
| 29 | ERBB3 | 1.33069139 |
| 30 | NUAK1 | 1.27140846 |
| 31 | LIMK1 | 1.25722466 |
| 32 | SRPK1 | 1.23906814 |
| 33 | TRIM28 | 1.18562450 |
| 34 | SYK | 1.14309516 |
| 35 | WNK4 | 1.09722213 |
| 36 | MAP4K1 | 1.06080930 |
| 37 | BMPR1B | 1.05503542 |
| 38 | BTK | 1.03920387 |
| 39 | IKBKB | 1.03098701 |
| 40 | CCNB1 | 1.00889943 |
| 41 | MAP2K6 | 0.96825407 |
| 42 | TSSK6 | 0.96324107 |
| 43 | IKBKE | 0.94843343 |
| 44 | MAP2K7 | 0.88871556 |
| 45 | GRK6 | 0.87987737 |
| 46 | WNK3 | 0.87326172 |
| 47 | NEK1 | 0.81444328 |
| 48 | PHKG2 | 0.80517702 |
| 49 | PHKG1 | 0.80517702 |
| 50 | CSNK1G3 | 0.79887576 |
| 51 | MAP3K14 | 0.78781930 |
| 52 | INSRR | 0.78056337 |
| 53 | MAPK13 | 0.77307027 |
| 54 | OXSR1 | 0.76997014 |
| 55 | PDK2 | 0.75759374 |
| 56 | FRK | 0.74677158 |
| 57 | EIF2AK3 | 0.74322243 |
| 58 | TBK1 | 0.71156381 |
| 59 | PLK3 | 0.70833363 |
| 60 | DAPK2 | 0.66728880 |
| 61 | PLK4 | 0.65164686 |
| 62 | GRK7 | 0.64971937 |
| 63 | JAK3 | 0.64820751 |
| 64 | LYN | 0.64515281 |
| 65 | EIF2AK2 | 0.63731477 |
| 66 | TRPM7 | 0.63616617 |
| 67 | CSNK1G1 | 0.56116774 |
| 68 | FES | 0.55183661 |
| 69 | CSNK1A1L | 0.55104767 |
| 70 | PRKCQ | 0.52038126 |
| 71 | IGF1R | 0.51964691 |
| 72 | DAPK3 | 0.49758806 |
| 73 | ADRBK1 | 0.48946056 |
| 74 | RPS6KA5 | 0.47277041 |
| 75 | DYRK2 | 0.46937143 |
| 76 | LCK | 0.45443757 |
| 77 | GRK5 | 0.44745832 |
| 78 | CSNK1G2 | 0.43557117 |
| 79 | CAMK2A | 0.42914799 |
| 80 | PRKCA | 0.41178832 |
| 81 | CSK | 0.39278863 |
| 82 | AURKB | 0.39066312 |
| 83 | OBSCN | 0.38876522 |
| 84 | PIM2 | 0.38696004 |
| 85 | CSNK2A1 | 0.38476917 |
| 86 | FLT3 | 0.37726433 |
| 87 | ILK | 0.37086052 |
| 88 | PAK4 | 0.36624036 |
| 89 | PRKACA | 0.36371176 |
| 90 | ATR | 0.36208078 |
| 91 | MAP3K4 | 0.35031207 |
| 92 | MAPKAPK5 | 0.34878745 |
| 93 | TGFBR1 | 0.34597055 |
| 94 | PBK | 0.34189936 |
| 95 | CHEK2 | 0.32851893 |
| 96 | KIT | 0.32020469 |
| 97 | PASK | 0.31491738 |
| 98 | CDK19 | 0.30871474 |
| 99 | ROCK1 | 0.29584842 |
| 100 | CSNK2A2 | 0.28856556 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.83531808 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.93900437 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.35978062 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.70954411 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.64881445 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.44971592 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.40714080 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.34359657 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.34239778 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.23041918 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.17566808 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.15254507 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.14506696 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.13534081 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 2.08641427 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.08136372 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.99465166 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.82559404 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.81067230 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.61933952 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.58381064 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.58194652 |
| 23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.45613527 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.38599414 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.37738190 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.36349221 |
| 27 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.29818138 |
| 28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.27207165 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.12195466 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10144079 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10083737 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.04146474 |
| 33 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.99390168 |
| 34 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.98225642 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 0.95080936 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 0.94501786 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 0.92833065 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92478265 |
| 39 | RNA degradation_Homo sapiens_hsa03018 | 0.91437840 |
| 40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.91276092 |
| 41 | DNA replication_Homo sapiens_hsa03030 | 0.90965026 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.88991687 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 0.88558383 |
| 44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86374659 |
| 45 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.86046292 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.85763735 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.84190501 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.81904394 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.81607782 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.81500292 |
| 51 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.80008500 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79425057 |
| 53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78789811 |
| 54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.78290734 |
| 55 | Spliceosome_Homo sapiens_hsa03040 | 0.76731237 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.75840206 |
| 57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75284453 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.73148603 |
| 59 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.72917570 |
| 60 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68268866 |
| 61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.65677018 |
| 62 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65256358 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64452640 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64352365 |
| 65 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.63501351 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.61092673 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.60414824 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59741431 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.57318387 |
| 70 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56744488 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.55309707 |
| 72 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50919405 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.49416360 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.48642312 |
| 75 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.46379158 |
| 76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46062207 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.44364087 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.41730864 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39531865 |
| 80 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.38760157 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.37046573 |
| 82 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36506793 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36197842 |
| 84 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35907446 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35792928 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34777766 |
| 87 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.33027411 |
| 88 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.32747186 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31975727 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.31923120 |
| 91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.31589614 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.30054596 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29750274 |
| 94 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.29540914 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28842449 |
| 96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.28769688 |
| 97 | Taste transduction_Homo sapiens_hsa04742 | 0.28291300 |
| 98 | Leishmaniasis_Homo sapiens_hsa05140 | 0.27764668 |
| 99 | Salmonella infection_Homo sapiens_hsa05132 | 0.26893799 |
| 100 | Nicotine addiction_Homo sapiens_hsa05033 | 0.25427249 |

