

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.92746473 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.75743476 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.75743476 |
| 4 | cell wall macromolecule catabolic process (GO:0016998) | 5.30671922 |
| 5 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.75979833 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 4.55862749 |
| 7 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.52024472 |
| 8 | cell wall macromolecule metabolic process (GO:0044036) | 4.40719213 |
| 9 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.40185463 |
| 10 | termination of RNA polymerase III transcription (GO:0006386) | 4.40185463 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 4.34157610 |
| 12 | cullin deneddylation (GO:0010388) | 4.28524998 |
| 13 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.09020050 |
| 14 | regulation of immunoglobulin secretion (GO:0051023) | 4.08625340 |
| 15 | rRNA modification (GO:0000154) | 4.03091260 |
| 16 | protein K6-linked ubiquitination (GO:0085020) | 3.95312513 |
| 17 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.91358869 |
| 18 | proteasome assembly (GO:0043248) | 3.89093251 |
| 19 | protein deneddylation (GO:0000338) | 3.82170609 |
| 20 | GTP biosynthetic process (GO:0006183) | 3.79980766 |
| 21 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.79145038 |
| 22 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.67475248 |
| 23 | maturation of SSU-rRNA (GO:0030490) | 3.58736411 |
| 24 | regulation of podosome assembly (GO:0071801) | 3.57859463 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.54541383 |
| 26 | interferon-gamma production (GO:0032609) | 3.52012384 |
| 27 | protein neddylation (GO:0045116) | 3.51202572 |
| 28 | protein complex biogenesis (GO:0070271) | 3.50684880 |
| 29 | positive regulation of isotype switching (GO:0045830) | 3.50152546 |
| 30 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49411760 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.47920352 |
| 32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.45844949 |
| 33 | NADH dehydrogenase complex assembly (GO:0010257) | 3.45844949 |
| 34 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.45844949 |
| 35 | positive regulation of DNA recombination (GO:0045911) | 3.44956441 |
| 36 | electron transport chain (GO:0022900) | 3.43536769 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.43486737 |
| 38 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.42694070 |
| 39 | viral transcription (GO:0019083) | 3.42645415 |
| 40 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.39677427 |
| 41 | translational termination (GO:0006415) | 3.38339368 |
| 42 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.37743298 |
| 43 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.35567592 |
| 44 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.35567592 |
| 45 | T-helper cell differentiation (GO:0042093) | 3.35314864 |
| 46 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.35314864 |
| 47 | UTP biosynthetic process (GO:0006228) | 3.34966910 |
| 48 | GMP metabolic process (GO:0046037) | 3.33110995 |
| 49 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.31452299 |
| 50 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.27387772 |
| 51 | cotranslational protein targeting to membrane (GO:0006613) | 3.27225866 |
| 52 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.27085147 |
| 53 | protein localization to kinetochore (GO:0034501) | 3.26307274 |
| 54 | protein targeting to ER (GO:0045047) | 3.25201877 |
| 55 | ATP biosynthetic process (GO:0006754) | 3.24405150 |
| 56 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.23378220 |
| 57 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.23378220 |
| 58 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.23378220 |
| 59 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.20489349 |
| 60 | negative regulation of ligase activity (GO:0051352) | 3.20202139 |
| 61 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.20202139 |
| 62 | DNA damage response, detection of DNA damage (GO:0042769) | 3.16887938 |
| 63 | inner mitochondrial membrane organization (GO:0007007) | 3.16722345 |
| 64 | pseudouridine synthesis (GO:0001522) | 3.16701473 |
| 65 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.16377283 |
| 66 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.16377283 |
| 67 | translation (GO:0006412) | 3.15777576 |
| 68 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.15656426 |
| 69 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.14954404 |
| 70 | autophagic vacuole fusion (GO:0000046) | 3.13179702 |
| 71 | protein localization to endoplasmic reticulum (GO:0070972) | 3.11828891 |
| 72 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.08106366 |
| 73 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.08106366 |
| 74 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.06990967 |
| 75 | negative regulation of B cell apoptotic process (GO:0002903) | 3.03697962 |
| 76 | translational elongation (GO:0006414) | 3.03421712 |
| 77 | UTP metabolic process (GO:0046051) | 3.01921456 |
| 78 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.01716673 |
| 79 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.01276138 |
| 80 | behavioral response to nicotine (GO:0035095) | 3.01207184 |
| 81 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.00914619 |
| 82 | mannosylation (GO:0097502) | 3.00748970 |
| 83 | rRNA methylation (GO:0031167) | 2.99461181 |
| 84 | regulation of mitochondrial translation (GO:0070129) | 2.97866231 |
| 85 | T cell differentiation involved in immune response (GO:0002292) | 2.97006133 |
| 86 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.97006133 |
| 87 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.97006133 |
| 88 | protein targeting to mitochondrion (GO:0006626) | 2.94434328 |
| 89 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.87928696 |
| 90 | positive regulation of organelle assembly (GO:1902117) | 2.87640259 |
| 91 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.85563067 |
| 92 | hydrogen ion transmembrane transport (GO:1902600) | 2.84686392 |
| 93 | positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) | 2.84488593 |
| 94 | translational initiation (GO:0006413) | 2.83582745 |
| 95 | ribosomal large subunit biogenesis (GO:0042273) | 2.83021492 |
| 96 | CTP metabolic process (GO:0046036) | 2.80819844 |
| 97 | CTP biosynthetic process (GO:0006241) | 2.80819844 |
| 98 | rRNA processing (GO:0006364) | 2.76487543 |
| 99 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.75577212 |
| 100 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.75577212 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.58421985 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.21410921 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.58526641 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.08588683 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.33193658 |
| 6 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.11305767 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01737762 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.94814007 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.93443104 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.88244673 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.81692964 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.80492795 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.76613517 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.76137469 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.60636053 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.50209298 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.47449495 |
| 18 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.26814818 |
| 19 | VDR_22108803_ChIP-Seq_LS180_Human | 2.26640019 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.19997759 |
| 21 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.18116542 |
| 22 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.06699778 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.94007141 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.89070517 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89049007 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.86699116 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80577642 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.73706912 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.72677272 |
| 30 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.71335981 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.70002367 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.69385121 |
| 33 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.68805416 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.68449754 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.66182903 |
| 36 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.64046025 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.62266476 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.58686251 |
| 39 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.58335461 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.56571838 |
| 41 | EWS_26573619_Chip-Seq_HEK293_Human | 1.52756285 |
| 42 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.51342939 |
| 43 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.49619394 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.47876569 |
| 45 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.42492368 |
| 46 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.37739822 |
| 47 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.36222555 |
| 48 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.35070417 |
| 49 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33552458 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28617358 |
| 51 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.24754179 |
| 52 | * AR_20517297_ChIP-Seq_VCAP_Human | 1.23031324 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.21277671 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.19601986 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.19601986 |
| 56 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.18990721 |
| 57 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.18752315 |
| 58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.17288997 |
| 59 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.15985503 |
| 60 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15052615 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.15010858 |
| 62 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.12713125 |
| 63 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.07030892 |
| 64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07030123 |
| 65 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.06567930 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06518274 |
| 67 | FUS_26573619_Chip-Seq_HEK293_Human | 1.06329055 |
| 68 | NCOR_22424771_ChIP-Seq_293T_Human | 1.04208601 |
| 69 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.03841146 |
| 70 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.03202303 |
| 71 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.03084839 |
| 72 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.02362156 |
| 73 | GATA3_26560356_Chip-Seq_TH2_Human | 1.01505065 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.00701005 |
| 75 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.00328934 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99948087 |
| 77 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99190982 |
| 78 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.98524790 |
| 79 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97183196 |
| 80 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96508583 |
| 81 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.94208293 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.93201156 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92294915 |
| 84 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.91978502 |
| 85 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90320289 |
| 86 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.90269323 |
| 87 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.89374619 |
| 88 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.89374619 |
| 89 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.88810483 |
| 90 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.87461690 |
| 91 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.86999702 |
| 92 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.85817465 |
| 93 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.85607078 |
| 94 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.84238017 |
| 95 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.83934257 |
| 96 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.83650152 |
| 97 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.80928688 |
| 98 | P300_19829295_ChIP-Seq_ESCs_Human | 0.79995342 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.78545979 |
| 100 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.77304044 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 3.34366035 |
| 2 | MP0003786_premature_aging | 2.98318299 |
| 3 | MP0008058_abnormal_DNA_repair | 2.76641354 |
| 4 | MP0005075_abnormal_melanosome_morpholog | 2.74583203 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.63455412 |
| 6 | MP0010386_abnormal_urinary_bladder | 2.49520996 |
| 7 | MP0001348_abnormal_lacrimal_gland | 2.40281818 |
| 8 | MP0001853_heart_inflammation | 2.27356311 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.26323334 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.22316872 |
| 11 | MP0008872_abnormal_physiological_respon | 2.21572507 |
| 12 | MP0006082_CNS_inflammation | 2.20510640 |
| 13 | MP0005671_abnormal_response_to | 2.15207606 |
| 14 | MP0001835_abnormal_antigen_presentation | 2.10296063 |
| 15 | MP0005084_abnormal_gallbladder_morpholo | 2.10209239 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 2.05259814 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 2.02162040 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 2.01130426 |
| 19 | MP0001984_abnormal_olfaction | 1.95713488 |
| 20 | MP0002138_abnormal_hepatobiliary_system | 1.95267808 |
| 21 | MP0010094_abnormal_chromosome_stability | 1.91457062 |
| 22 | MP0000465_gastrointestinal_hemorrhage | 1.86720532 |
| 23 | MP0004957_abnormal_blastocyst_morpholog | 1.82337086 |
| 24 | MP0002102_abnormal_ear_morphology | 1.80311073 |
| 25 | MP0002736_abnormal_nociception_after | 1.67576784 |
| 26 | MP0002234_abnormal_pharynx_morphology | 1.65148212 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.60253888 |
| 28 | MP0003866_abnormal_defecation | 1.55643926 |
| 29 | MP0002837_dystrophic_cardiac_calcinosis | 1.55085620 |
| 30 | MP0003195_calcinosis | 1.54844422 |
| 31 | MP0005310_abnormal_salivary_gland | 1.52901016 |
| 32 | MP0000427_abnormal_hair_cycle | 1.51458446 |
| 33 | MP0006036_abnormal_mitochondrial_physio | 1.48204316 |
| 34 | MP0005499_abnormal_olfactory_system | 1.47810798 |
| 35 | MP0005394_taste/olfaction_phenotype | 1.47810798 |
| 36 | MP0001873_stomach_inflammation | 1.46534963 |
| 37 | MP0005083_abnormal_biliary_tract | 1.45008947 |
| 38 | MP0004043_abnormal_pH_regulation | 1.43439265 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.42480420 |
| 40 | MP0004142_abnormal_muscle_tone | 1.41808868 |
| 41 | MP0002139_abnormal_hepatobiliary_system | 1.41157490 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.38755805 |
| 43 | MP0003718_maternal_effect | 1.38398907 |
| 44 | MP0002148_abnormal_hypersensitivity_rea | 1.37830774 |
| 45 | MP0003186_abnormal_redox_activity | 1.35906932 |
| 46 | MP0002095_abnormal_skin_pigmentation | 1.33198263 |
| 47 | MP0002876_abnormal_thyroid_physiology | 1.31445543 |
| 48 | MP0002163_abnormal_gland_morphology | 1.29346004 |
| 49 | MP0004019_abnormal_vitamin_homeostasis | 1.27311926 |
| 50 | MP0006292_abnormal_olfactory_placode | 1.24785638 |
| 51 | MP0004145_abnormal_muscle_electrophysio | 1.23329197 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.21135562 |
| 53 | MP0005085_abnormal_gallbladder_physiolo | 1.20859379 |
| 54 | MP0002822_catalepsy | 1.16987123 |
| 55 | MP0005636_abnormal_mineral_homeostasis | 1.15538287 |
| 56 | MP0004885_abnormal_endolymph | 1.12381642 |
| 57 | MP0005253_abnormal_eye_physiology | 1.12319383 |
| 58 | MP0003011_delayed_dark_adaptation | 1.11065125 |
| 59 | MP0009046_muscle_twitch | 1.08211946 |
| 60 | MP0001529_abnormal_vocalization | 1.07858725 |
| 61 | MP0001293_anophthalmia | 1.07536780 |
| 62 | MP0003693_abnormal_embryo_hatching | 1.05083181 |
| 63 | MP0001968_abnormal_touch/_nociception | 1.04737615 |
| 64 | MP0002938_white_spotting | 1.03449526 |
| 65 | MP0009785_altered_susceptibility_to | 1.02378141 |
| 66 | MP0000647_abnormal_sebaceous_gland | 0.99646650 |
| 67 | MP0003724_increased_susceptibility_to | 0.97258851 |
| 68 | MP0001986_abnormal_taste_sensitivity | 0.95352623 |
| 69 | MP0005319_abnormal_enzyme/_coenzyme | 0.93470615 |
| 70 | MP0003252_abnormal_bile_duct | 0.93137693 |
| 71 | MP0001800_abnormal_humoral_immune | 0.92209631 |
| 72 | MP0001765_abnormal_ion_homeostasis | 0.91429824 |
| 73 | MP0005377_hearing/vestibular/ear_phenot | 0.91039172 |
| 74 | MP0003878_abnormal_ear_physiology | 0.91039172 |
| 75 | MP0001542_abnormal_bone_strength | 0.89929169 |
| 76 | MP0005332_abnormal_amino_acid | 0.88778647 |
| 77 | MP0000372_irregular_coat_pigmentation | 0.88574086 |
| 78 | MP0000383_abnormal_hair_follicle | 0.87885497 |
| 79 | MP0003763_abnormal_thymus_physiology | 0.87074403 |
| 80 | MP0005000_abnormal_immune_tolerance | 0.86170785 |
| 81 | MP0002272_abnormal_nervous_system | 0.86049301 |
| 82 | MP0003077_abnormal_cell_cycle | 0.83085164 |
| 83 | MP0000579_abnormal_nail_morphology | 0.83020355 |
| 84 | MP0001485_abnormal_pinna_reflex | 0.81389029 |
| 85 | MP0001501_abnormal_sleep_pattern | 0.81066094 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.79382789 |
| 87 | MP0002090_abnormal_vision | 0.78528348 |
| 88 | MP0001764_abnormal_homeostasis | 0.78472012 |
| 89 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77934630 |
| 90 | MP0005646_abnormal_pituitary_gland | 0.77727077 |
| 91 | MP0002229_neurodegeneration | 0.77536181 |
| 92 | MP0004381_abnormal_hair_follicle | 0.76876939 |
| 93 | MP0002723_abnormal_immune_serum | 0.74621402 |
| 94 | MP0005379_endocrine/exocrine_gland_phen | 0.73320887 |
| 95 | MP0001819_abnormal_immune_cell | 0.72976316 |
| 96 | MP0000749_muscle_degeneration | 0.72291210 |
| 97 | MP0001346_abnormal_lacrimal_gland | 0.72208734 |
| 98 | MP0002420_abnormal_adaptive_immunity | 0.71954810 |
| 99 | MP0003119_abnormal_digestive_system | 0.71588675 |
| 100 | MP0009697_abnormal_copulation | 0.71325436 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Lipid accumulation in hepatocytes (HP:0006561) | 4.73914061 |
| 2 | Methylmalonic acidemia (HP:0002912) | 4.01729374 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 3.96206977 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.93362299 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.89075881 |
| 6 | Reticulocytopenia (HP:0001896) | 3.82513109 |
| 7 | Congenital, generalized hypertrichosis (HP:0004540) | 3.70012536 |
| 8 | Duplicated collecting system (HP:0000081) | 3.62488887 |
| 9 | Increased CSF lactate (HP:0002490) | 3.59277851 |
| 10 | Abnormal number of erythroid precursors (HP:0012131) | 3.49333572 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.48703418 |
| 12 | Abnormality of the renal collecting system (HP:0004742) | 3.36346549 |
| 13 | Large for gestational age (HP:0001520) | 3.32227542 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.31129658 |
| 15 | Type I transferrin isoform profile (HP:0003642) | 3.24364260 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.23578337 |
| 17 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.22487996 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.21713419 |
| 19 | Parakeratosis (HP:0001036) | 3.18098086 |
| 20 | Hepatic necrosis (HP:0002605) | 3.15757752 |
| 21 | Progressive macrocephaly (HP:0004481) | 3.15347478 |
| 22 | Acute encephalopathy (HP:0006846) | 3.15209993 |
| 23 | Microvesicular hepatic steatosis (HP:0001414) | 3.09896612 |
| 24 | Beaking of vertebral bodies (HP:0004568) | 3.09679290 |
| 25 | Methylmalonic aciduria (HP:0012120) | 3.09329766 |
| 26 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.08866629 |
| 27 | Stomatitis (HP:0010280) | 3.08631244 |
| 28 | Ureteral duplication (HP:0000073) | 3.03727623 |
| 29 | Pancytopenia (HP:0001876) | 2.96073916 |
| 30 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.89950755 |
| 31 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.89950755 |
| 32 | Abnormal protein glycosylation (HP:0012346) | 2.89950755 |
| 33 | Abnormal glycosylation (HP:0012345) | 2.89950755 |
| 34 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.85687248 |
| 35 | IgG deficiency (HP:0004315) | 2.85162607 |
| 36 | Cerebral edema (HP:0002181) | 2.84550541 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.83060512 |
| 38 | Pancreatic cysts (HP:0001737) | 2.82772166 |
| 39 | Colon cancer (HP:0003003) | 2.79638624 |
| 40 | Macrocytic anemia (HP:0001972) | 2.77966639 |
| 41 | Increased serum lactate (HP:0002151) | 2.72037655 |
| 42 | Pendular nystagmus (HP:0012043) | 2.69294387 |
| 43 | Exertional dyspnea (HP:0002875) | 2.56643426 |
| 44 | Sparse eyelashes (HP:0000653) | 2.55614107 |
| 45 | Congenital primary aphakia (HP:0007707) | 2.54992401 |
| 46 | Increased muscle lipid content (HP:0009058) | 2.53880729 |
| 47 | Testicular atrophy (HP:0000029) | 2.52919650 |
| 48 | Medial flaring of the eyebrow (HP:0010747) | 2.50515797 |
| 49 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.47827129 |
| 50 | Hyperglycinemia (HP:0002154) | 2.46711042 |
| 51 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.45492369 |
| 52 | Dicarboxylic aciduria (HP:0003215) | 2.45492369 |
| 53 | Abnormality of vitamin B metabolism (HP:0004340) | 2.42970402 |
| 54 | Chromsome breakage (HP:0040012) | 2.41811875 |
| 55 | Gait imbalance (HP:0002141) | 2.40931734 |
| 56 | Optic disc pallor (HP:0000543) | 2.40274205 |
| 57 | Abnormality of renal resorption (HP:0011038) | 2.33053476 |
| 58 | Lethargy (HP:0001254) | 2.32633726 |
| 59 | Lactic acidosis (HP:0003128) | 2.29541328 |
| 60 | Abnormality of dental color (HP:0011073) | 2.28703037 |
| 61 | Nephrogenic diabetes insipidus (HP:0009806) | 2.28428638 |
| 62 | Hypoplasia of the pons (HP:0012110) | 2.27457573 |
| 63 | Respiratory difficulties (HP:0002880) | 2.26666854 |
| 64 | Pancreatic fibrosis (HP:0100732) | 2.24779044 |
| 65 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.21973827 |
| 66 | Abnormality of the pons (HP:0007361) | 2.20040628 |
| 67 | Abnormality of homocysteine metabolism (HP:0010919) | 2.19942588 |
| 68 | Homocystinuria (HP:0002156) | 2.19942588 |
| 69 | Increased intramyocellular lipid droplets (HP:0012240) | 2.19075432 |
| 70 | Attenuation of retinal blood vessels (HP:0007843) | 2.18365225 |
| 71 | Abnormality of the ileum (HP:0001549) | 2.16605343 |
| 72 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.15818969 |
| 73 | Degeneration of anterior horn cells (HP:0002398) | 2.14900486 |
| 74 | Abnormality of the anterior horn cell (HP:0006802) | 2.14900486 |
| 75 | Reduced antithrombin III activity (HP:0001976) | 2.14740117 |
| 76 | Abnormality of methionine metabolism (HP:0010901) | 2.12181896 |
| 77 | Respiratory failure (HP:0002878) | 2.11036485 |
| 78 | Meckel diverticulum (HP:0002245) | 2.10587879 |
| 79 | Abnormality of serum amino acid levels (HP:0003112) | 2.08893088 |
| 80 | Poor head control (HP:0002421) | 2.07429995 |
| 81 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.06101655 |
| 82 | Abnormality of glycine metabolism (HP:0010895) | 2.06101655 |
| 83 | True hermaphroditism (HP:0010459) | 2.01602623 |
| 84 | Increased corneal curvature (HP:0100692) | 2.00044485 |
| 85 | Keratoconus (HP:0000563) | 2.00044485 |
| 86 | Abolished electroretinogram (ERG) (HP:0000550) | 1.99579216 |
| 87 | Exercise intolerance (HP:0003546) | 1.98153015 |
| 88 | Erythroderma (HP:0001019) | 1.98134001 |
| 89 | Megaloblastic anemia (HP:0001889) | 1.96555018 |
| 90 | Absent thumb (HP:0009777) | 1.94007566 |
| 91 | Abnormality of alanine metabolism (HP:0010916) | 1.90293381 |
| 92 | Hyperalaninemia (HP:0003348) | 1.90293381 |
| 93 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.90293381 |
| 94 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.90207461 |
| 95 | Vaginal atresia (HP:0000148) | 1.88294754 |
| 96 | Congenital sensorineural hearing impairment (HP:0008527) | 1.87433524 |
| 97 | Progressive microcephaly (HP:0000253) | 1.85910876 |
| 98 | CNS demyelination (HP:0007305) | 1.85550362 |
| 99 | Sclerocornea (HP:0000647) | 1.84094545 |
| 100 | Aplastic anemia (HP:0001915) | 1.83404484 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME1 | 5.21521888 |
| 2 | TXK | 4.71795612 |
| 3 | VRK2 | 4.71664501 |
| 4 | PBK | 3.54272313 |
| 5 | MST4 | 3.31678052 |
| 6 | ZAK | 3.06276737 |
| 7 | EIF2AK1 | 2.93144255 |
| 8 | STK16 | 2.54897945 |
| 9 | VRK1 | 2.34570409 |
| 10 | SRPK1 | 2.17852357 |
| 11 | NUAK1 | 2.02213597 |
| 12 | GRK7 | 2.01599307 |
| 13 | WNK4 | 2.01487627 |
| 14 | EIF2AK3 | 1.77314353 |
| 15 | ADRBK2 | 1.72276038 |
| 16 | BUB1 | 1.65655431 |
| 17 | BMPR1B | 1.56289345 |
| 18 | GRK5 | 1.53267588 |
| 19 | ACVR1B | 1.44349742 |
| 20 | TLK1 | 1.41329409 |
| 21 | BCKDK | 1.39073017 |
| 22 | PLK4 | 1.38514387 |
| 23 | NEK1 | 1.38008576 |
| 24 | MOS | 1.37193999 |
| 25 | PDK2 | 1.31505736 |
| 26 | EIF2AK2 | 1.31363806 |
| 27 | GRK1 | 1.31317525 |
| 28 | PASK | 1.25962885 |
| 29 | PLK3 | 1.23854456 |
| 30 | MAP3K4 | 1.14607464 |
| 31 | LMTK2 | 1.13158919 |
| 32 | STK10 | 1.11490118 |
| 33 | TAF1 | 1.07093406 |
| 34 | MAP3K12 | 1.04735992 |
| 35 | ITK | 1.04735927 |
| 36 | OXSR1 | 1.04574078 |
| 37 | DAPK1 | 0.97986427 |
| 38 | FES | 0.95863926 |
| 39 | IRAK4 | 0.93548430 |
| 40 | TAOK3 | 0.93072408 |
| 41 | MAP4K2 | 0.92633142 |
| 42 | MAP2K6 | 0.89914462 |
| 43 | IKBKB | 0.89633298 |
| 44 | NEK2 | 0.85140350 |
| 45 | TGFBR2 | 0.84912985 |
| 46 | WNK3 | 0.81022787 |
| 47 | MAP2K2 | 0.79989003 |
| 48 | TEC | 0.79855196 |
| 49 | ADRBK1 | 0.79500707 |
| 50 | INSRR | 0.77612776 |
| 51 | STK39 | 0.76409132 |
| 52 | AURKB | 0.75593756 |
| 53 | PLK1 | 0.70554846 |
| 54 | TGFBR1 | 0.69897548 |
| 55 | TNIK | 0.68628542 |
| 56 | TSSK6 | 0.68450805 |
| 57 | KIT | 0.68121853 |
| 58 | BRSK2 | 0.67668249 |
| 59 | PAK4 | 0.64639201 |
| 60 | FRK | 0.59233827 |
| 61 | MYLK | 0.58555923 |
| 62 | PINK1 | 0.56791391 |
| 63 | TTK | 0.56130581 |
| 64 | MKNK1 | 0.54722725 |
| 65 | ATR | 0.54436285 |
| 66 | STK38L | 0.48217873 |
| 67 | CDC7 | 0.48090769 |
| 68 | TRIM28 | 0.46018951 |
| 69 | MATK | 0.43115945 |
| 70 | AURKA | 0.42754854 |
| 71 | IGF1R | 0.41512780 |
| 72 | MST1R | 0.40790236 |
| 73 | DAPK2 | 0.40591862 |
| 74 | MELK | 0.40196526 |
| 75 | PRKCQ | 0.37786783 |
| 76 | CSNK2A1 | 0.37717221 |
| 77 | NME2 | 0.37296879 |
| 78 | STK4 | 0.36798514 |
| 79 | CHEK2 | 0.35351633 |
| 80 | CSNK2A2 | 0.35331934 |
| 81 | CSF1R | 0.33525362 |
| 82 | KDR | 0.33360259 |
| 83 | LYN | 0.33012419 |
| 84 | DYRK2 | 0.32645251 |
| 85 | MKNK2 | 0.31540352 |
| 86 | TIE1 | 0.31493959 |
| 87 | RPS6KA5 | 0.30873153 |
| 88 | MAPKAPK5 | 0.30377437 |
| 89 | PIK3CG | 0.29847140 |
| 90 | CHUK | 0.29775429 |
| 91 | BRD4 | 0.28794064 |
| 92 | PHKG2 | 0.28331998 |
| 93 | PHKG1 | 0.28331998 |
| 94 | MUSK | 0.27496917 |
| 95 | RPS6KB2 | 0.26625034 |
| 96 | TBK1 | 0.26029217 |
| 97 | MAPK13 | 0.24485541 |
| 98 | PRKCG | 0.23755162 |
| 99 | PLK2 | 0.22882892 |
| 100 | LIMK1 | 0.21975513 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.11740248 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.69797285 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.44549890 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.33127739 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.92844304 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.78261064 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.51968261 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.44965635 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.38645936 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.23814193 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 2.16675079 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.03239196 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.02933711 |
| 14 | Allograft rejection_Homo sapiens_hsa05330 | 1.97320511 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.96190099 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.90842475 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.89110983 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.86582389 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78131561 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.71076563 |
| 21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.67492975 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64816151 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.56845093 |
| 24 | Spliceosome_Homo sapiens_hsa03040 | 1.56117925 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.49770173 |
| 26 | Purine metabolism_Homo sapiens_hsa00230 | 1.46441680 |
| 27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.44433768 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.42010901 |
| 29 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.41949539 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.41707534 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.32251119 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.30107067 |
| 33 | Phototransduction_Homo sapiens_hsa04744 | 1.27605636 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.27538780 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.21075791 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.19205507 |
| 37 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08179676 |
| 38 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.00381129 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.99098996 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.93571214 |
| 41 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.92380253 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89439344 |
| 43 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.89329139 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.88919043 |
| 45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.88341583 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85999339 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.82611409 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80274342 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80227972 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75345030 |
| 51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.73932475 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.73711786 |
| 53 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.73339709 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72328324 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.72306570 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72056734 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.71823198 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70666303 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68498620 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66569870 |
| 61 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.64755359 |
| 62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.63594259 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63561494 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62386416 |
| 65 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.61748134 |
| 66 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61192964 |
| 67 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.61034148 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58109152 |
| 69 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.58025673 |
| 70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.56871686 |
| 71 | Olfactory transduction_Homo sapiens_hsa04740 | 0.56762284 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.56255412 |
| 73 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52498032 |
| 74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52161555 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.51459864 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.51075907 |
| 77 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.49319618 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47916007 |
| 79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.47760611 |
| 80 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.47548391 |
| 81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.47062636 |
| 82 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46575940 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42690009 |
| 84 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41240137 |
| 85 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.40036791 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38898004 |
| 87 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.37157031 |
| 88 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.36041695 |
| 89 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.35893893 |
| 90 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.33209333 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.33169918 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.32694564 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.31487384 |
| 94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30772869 |
| 95 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.30523600 |
| 96 | Nicotine addiction_Homo sapiens_hsa05033 | 0.27818966 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.27777028 |
| 98 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.22796575 |
| 99 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.22116310 |
| 100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20837074 |

