

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.24320136 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.17699273 |
| 3 | cytidine deamination (GO:0009972) | 6.14629457 |
| 4 | cytidine metabolic process (GO:0046087) | 6.14629457 |
| 5 | cytidine catabolic process (GO:0006216) | 6.14629457 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.62516751 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.55023728 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 5.30611051 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.30611051 |
| 10 | sequestering of actin monomers (GO:0042989) | 4.92932624 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.47324189 |
| 12 | respiratory electron transport chain (GO:0022904) | 4.39647241 |
| 13 | electron transport chain (GO:0022900) | 4.33726048 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.31554047 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.26786046 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.19041450 |
| 17 | ribosomal small subunit assembly (GO:0000028) | 4.16703257 |
| 18 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.07147931 |
| 19 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.07147931 |
| 20 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.07147931 |
| 21 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.06769118 |
| 22 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.06769118 |
| 23 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.98782005 |
| 24 | proteasome assembly (GO:0043248) | 3.97346078 |
| 25 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.93542352 |
| 26 | protein deneddylation (GO:0000338) | 3.86942443 |
| 27 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.86188295 |
| 28 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.86188295 |
| 29 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.81414885 |
| 30 | protein neddylation (GO:0045116) | 3.80121063 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.79704698 |
| 32 | negative regulation of ligase activity (GO:0051352) | 3.79704698 |
| 33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.78312147 |
| 34 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.78295599 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.73712603 |
| 36 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.70903742 |
| 37 | cullin deneddylation (GO:0010388) | 3.67737385 |
| 38 | protein complex biogenesis (GO:0070271) | 3.65281237 |
| 39 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.62373512 |
| 40 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.57881627 |
| 41 | termination of RNA polymerase III transcription (GO:0006386) | 3.57881627 |
| 42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.54173133 |
| 43 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.52634794 |
| 44 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.47450687 |
| 45 | ubiquinone biosynthetic process (GO:0006744) | 3.43850228 |
| 46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.43577210 |
| 47 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.43577210 |
| 48 | NADH dehydrogenase complex assembly (GO:0010257) | 3.43577210 |
| 49 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.40471210 |
| 50 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.38345901 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.36868724 |
| 52 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.32373375 |
| 53 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.32373375 |
| 54 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.25411814 |
| 55 | actin nucleation (GO:0045010) | 3.24597430 |
| 56 | base-excision repair, AP site formation (GO:0006285) | 3.23587824 |
| 57 | platelet dense granule organization (GO:0060155) | 3.22108465 |
| 58 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.19814163 |
| 59 | positive regulation of ligase activity (GO:0051351) | 3.18285068 |
| 60 | regulation of cellular amine metabolic process (GO:0033238) | 3.13730021 |
| 61 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.12750860 |
| 62 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.12132670 |
| 63 | ubiquinone metabolic process (GO:0006743) | 3.08535713 |
| 64 | hydrogen ion transmembrane transport (GO:1902600) | 3.08184676 |
| 65 | regulation of chronic inflammatory response (GO:0002676) | 3.05708197 |
| 66 | positive regulation of cell cycle arrest (GO:0071158) | 3.03364798 |
| 67 | iron-sulfur cluster assembly (GO:0016226) | 2.94133324 |
| 68 | metallo-sulfur cluster assembly (GO:0031163) | 2.94133324 |
| 69 | ATP biosynthetic process (GO:0006754) | 2.89646538 |
| 70 | proton transport (GO:0015992) | 2.88403502 |
| 71 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.85738976 |
| 72 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85240962 |
| 73 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.84401563 |
| 74 | quinone biosynthetic process (GO:1901663) | 2.83970924 |
| 75 | respiratory chain complex IV assembly (GO:0008535) | 2.82625323 |
| 76 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.82438993 |
| 77 | behavioral response to nicotine (GO:0035095) | 2.82348738 |
| 78 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.81597568 |
| 79 | hydrogen transport (GO:0006818) | 2.81297565 |
| 80 | positive regulation of prostaglandin secretion (GO:0032308) | 2.80553694 |
| 81 | mannosylation (GO:0097502) | 2.76678067 |
| 82 | cytolysis (GO:0019835) | 2.74653997 |
| 83 | response to interferon-beta (GO:0035456) | 2.74077291 |
| 84 | protein targeting to mitochondrion (GO:0006626) | 2.72831150 |
| 85 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.70771493 |
| 86 | aldehyde catabolic process (GO:0046185) | 2.70109734 |
| 87 | deoxyribonucleotide catabolic process (GO:0009264) | 2.69711719 |
| 88 | regulation of ligase activity (GO:0051340) | 2.69177646 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.68765706 |
| 90 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.68606002 |
| 91 | GTP biosynthetic process (GO:0006183) | 2.67792474 |
| 92 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.67667396 |
| 93 | cytochrome complex assembly (GO:0017004) | 2.65568662 |
| 94 | negative regulation of T cell apoptotic process (GO:0070233) | 2.63325992 |
| 95 | establishment of protein localization to mitochondrion (GO:0072655) | 2.62162542 |
| 96 | maturation of SSU-rRNA (GO:0030490) | 2.60307049 |
| 97 | ribosomal large subunit biogenesis (GO:0042273) | 2.59907195 |
| 98 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.59234233 |
| 99 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.58210440 |
| 100 | spliceosomal snRNP assembly (GO:0000387) | 2.58209854 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.89048963 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.39464321 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.98675545 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.94359480 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.59110420 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.45389289 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.10396149 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.07268088 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.92825764 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.90451377 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.83296349 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.62015811 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.54084439 |
| 14 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.37204972 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.36516470 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.32843204 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.25108709 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.22725874 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.18117240 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.07502297 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.99774716 |
| 22 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.93286819 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.92980059 |
| 24 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.92854706 |
| 25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.89958661 |
| 26 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.83551419 |
| 27 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81034870 |
| 28 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.80141569 |
| 29 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.78863602 |
| 30 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.70567640 |
| 31 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.69711372 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.68624536 |
| 33 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.61256240 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.59821261 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56754349 |
| 36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55776835 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.54954792 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.52553822 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.51649614 |
| 40 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.51501045 |
| 41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51335201 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.44655593 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.41585992 |
| 44 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.40967762 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40836971 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.39021955 |
| 47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.38762181 |
| 48 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.37461798 |
| 49 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.35907766 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35695404 |
| 51 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.35690200 |
| 52 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.34127978 |
| 53 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.32839329 |
| 54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.31821928 |
| 55 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27220889 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26974145 |
| 57 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.26833219 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.26721739 |
| 59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.26452961 |
| 60 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26167935 |
| 61 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.24882603 |
| 62 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23415628 |
| 63 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.23341977 |
| 64 | GATA3_26560356_Chip-Seq_TH2_Human | 1.22694128 |
| 65 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22097415 |
| 66 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.21853386 |
| 67 | MYB_26560356_Chip-Seq_TH2_Human | 1.21146985 |
| 68 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.16992965 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.16149932 |
| 70 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12500668 |
| 71 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.10685109 |
| 72 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10063723 |
| 73 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.09404017 |
| 74 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08173730 |
| 75 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06725189 |
| 76 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.06251648 |
| 77 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05796132 |
| 78 | EWS_26573619_Chip-Seq_HEK293_Human | 1.04713781 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04182216 |
| 80 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.03788808 |
| 81 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03677356 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02173626 |
| 83 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02173626 |
| 84 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.00726167 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97738118 |
| 86 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.95565999 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.95525092 |
| 88 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.94499209 |
| 89 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.91071712 |
| 90 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.90408474 |
| 91 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90233625 |
| 92 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89740556 |
| 93 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89589515 |
| 94 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88901470 |
| 95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87831544 |
| 96 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.87613719 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.87188205 |
| 98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87179847 |
| 99 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.85608887 |
| 100 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.85482591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.53899071 |
| 2 | MP0002102_abnormal_ear_morphology | 2.88377247 |
| 3 | MP0008872_abnormal_physiological_respon | 2.48521188 |
| 4 | MP0003786_premature_aging | 2.38648943 |
| 5 | MP0002138_abnormal_hepatobiliary_system | 2.37341805 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.34436427 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.22650126 |
| 8 | MP0003763_abnormal_thymus_physiology | 2.19124988 |
| 9 | MP0009785_altered_susceptibility_to | 2.16636743 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.15568099 |
| 11 | MP0002166_altered_tumor_susceptibility | 2.10668288 |
| 12 | MP0001835_abnormal_antigen_presentation | 1.98977588 |
| 13 | MP0002006_tumorigenesis | 1.97810291 |
| 14 | MP0006036_abnormal_mitochondrial_physio | 1.97209070 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 1.94893666 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.94554817 |
| 17 | MP0008058_abnormal_DNA_repair | 1.91514109 |
| 18 | MP0001529_abnormal_vocalization | 1.80880060 |
| 19 | MP0008877_abnormal_DNA_methylation | 1.79484325 |
| 20 | MP0006035_abnormal_mitochondrial_morpho | 1.77341494 |
| 21 | MP0001873_stomach_inflammation | 1.71383280 |
| 22 | MP0002837_dystrophic_cardiac_calcinosis | 1.70020136 |
| 23 | MP0004147_increased_porphyrin_level | 1.68642135 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.66473595 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.66283792 |
| 26 | MP0000372_irregular_coat_pigmentation | 1.64975655 |
| 27 | MP0002163_abnormal_gland_morphology | 1.64582084 |
| 28 | MP0001905_abnormal_dopamine_level | 1.59119435 |
| 29 | MP0001800_abnormal_humoral_immune | 1.57202052 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.56524740 |
| 31 | MP0002736_abnormal_nociception_after | 1.54959605 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.46569890 |
| 33 | MP0002638_abnormal_pupillary_reflex | 1.46238697 |
| 34 | MP0003718_maternal_effect | 1.45858847 |
| 35 | MP0006276_abnormal_autonomic_nervous | 1.45281444 |
| 36 | MP0001919_abnormal_reproductive_system | 1.44449996 |
| 37 | MP0005000_abnormal_immune_tolerance | 1.44017486 |
| 38 | MP0010094_abnormal_chromosome_stability | 1.41359671 |
| 39 | MP0003878_abnormal_ear_physiology | 1.40947212 |
| 40 | MP0005377_hearing/vestibular/ear_phenot | 1.40947212 |
| 41 | MP0003646_muscle_fatigue | 1.40512282 |
| 42 | MP0009697_abnormal_copulation | 1.40225296 |
| 43 | MP0002420_abnormal_adaptive_immunity | 1.38367700 |
| 44 | MP0002723_abnormal_immune_serum | 1.37049461 |
| 45 | MP0005360_urolithiasis | 1.37017298 |
| 46 | MP0003866_abnormal_defecation | 1.36300119 |
| 47 | MP0003806_abnormal_nucleotide_metabolis | 1.35088822 |
| 48 | MP0001819_abnormal_immune_cell | 1.34845980 |
| 49 | MP0002653_abnormal_ependyma_morphology | 1.31020601 |
| 50 | MP0005551_abnormal_eye_electrophysiolog | 1.30013998 |
| 51 | MP0005025_abnormal_response_to | 1.27971759 |
| 52 | MP0001984_abnormal_olfaction | 1.24530729 |
| 53 | MP0001485_abnormal_pinna_reflex | 1.22910816 |
| 54 | MP0002452_abnormal_antigen_presenting | 1.21542547 |
| 55 | MP0008995_early_reproductive_senescence | 1.19149547 |
| 56 | MP0000685_abnormal_immune_system | 1.17630235 |
| 57 | MP0005389_reproductive_system_phenotype | 1.16134655 |
| 58 | MP0003195_calcinosis | 1.13663082 |
| 59 | MP0005085_abnormal_gallbladder_physiolo | 1.13103059 |
| 60 | MP0002876_abnormal_thyroid_physiology | 1.12394710 |
| 61 | MP0001764_abnormal_homeostasis | 1.11675007 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.11356232 |
| 63 | MP0003693_abnormal_embryo_hatching | 1.09321328 |
| 64 | MP0001986_abnormal_taste_sensitivity | 1.09036569 |
| 65 | MP0002234_abnormal_pharynx_morphology | 1.07862801 |
| 66 | MP0005646_abnormal_pituitary_gland | 1.07371115 |
| 67 | MP0000716_abnormal_immune_system | 1.06295941 |
| 68 | MP0001790_abnormal_immune_system | 1.05978067 |
| 69 | MP0005387_immune_system_phenotype | 1.05978067 |
| 70 | MP0005253_abnormal_eye_physiology | 1.05832649 |
| 71 | MP0006082_CNS_inflammation | 1.05167634 |
| 72 | MP0003787_abnormal_imprinting | 1.04441370 |
| 73 | MP0004142_abnormal_muscle_tone | 1.04422356 |
| 74 | MP0005410_abnormal_fertilization | 1.03899889 |
| 75 | MP0009764_decreased_sensitivity_to | 1.02732256 |
| 76 | MP0010386_abnormal_urinary_bladder | 1.02216801 |
| 77 | MP0004957_abnormal_blastocyst_morpholog | 1.01727510 |
| 78 | MP0002398_abnormal_bone_marrow | 1.01520652 |
| 79 | MP0002822_catalepsy | 1.00623225 |
| 80 | MP0000689_abnormal_spleen_morphology | 1.00525923 |
| 81 | MP0001845_abnormal_inflammatory_respons | 0.99880096 |
| 82 | MP0000703_abnormal_thymus_morphology | 0.98574820 |
| 83 | MP0005379_endocrine/exocrine_gland_phen | 0.96820746 |
| 84 | MP0001853_heart_inflammation | 0.96746614 |
| 85 | MP0003011_delayed_dark_adaptation | 0.95155013 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.94599693 |
| 87 | MP0004742_abnormal_vestibular_system | 0.94021097 |
| 88 | MP0003186_abnormal_redox_activity | 0.90851539 |
| 89 | MP0002722_abnormal_immune_system | 0.89499911 |
| 90 | MP0005075_abnormal_melanosome_morpholog | 0.89473406 |
| 91 | MP0008469_abnormal_protein_level | 0.89130519 |
| 92 | MP0005394_taste/olfaction_phenotype | 0.88744134 |
| 93 | MP0005499_abnormal_olfactory_system | 0.88744134 |
| 94 | MP0009379_abnormal_foot_pigmentation | 0.88271984 |
| 95 | MP0002405_respiratory_system_inflammati | 0.85497839 |
| 96 | MP0002429_abnormal_blood_cell | 0.83020586 |
| 97 | MP0003252_abnormal_bile_duct | 0.82142974 |
| 98 | MP0001501_abnormal_sleep_pattern | 0.78818355 |
| 99 | MP0002019_abnormal_tumor_incidence | 0.78106268 |
| 100 | MP0001119_abnormal_female_reproductive | 0.77140244 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.98263873 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.74907172 |
| 3 | Aplastic anemia (HP:0001915) | 4.64755892 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.60914099 |
| 5 | Acute encephalopathy (HP:0006846) | 4.42356688 |
| 6 | Increased CSF lactate (HP:0002490) | 4.20996592 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.08837402 |
| 8 | Progressive macrocephaly (HP:0004481) | 4.04927327 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.85065146 |
| 10 | Hepatic necrosis (HP:0002605) | 3.74359580 |
| 11 | IgG deficiency (HP:0004315) | 3.47477548 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.43517357 |
| 13 | Cerebral edema (HP:0002181) | 3.42830047 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 3.30653649 |
| 15 | Abnormality of T cell number (HP:0011839) | 3.27222386 |
| 16 | Abnormality of B cell number (HP:0010975) | 3.12937203 |
| 17 | Increased intramyocellular lipid droplets (HP:0012240) | 3.08089039 |
| 18 | T lymphocytopenia (HP:0005403) | 3.06201634 |
| 19 | Pancytopenia (HP:0001876) | 3.05524917 |
| 20 | Increased serum lactate (HP:0002151) | 3.03192996 |
| 21 | Severe combined immunodeficiency (HP:0004430) | 3.00976118 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 2.96861564 |
| 23 | Hypoproteinemia (HP:0003075) | 2.95604512 |
| 24 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.89173999 |
| 25 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.89016435 |
| 26 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.89016435 |
| 27 | Congenital stationary night blindness (HP:0007642) | 2.88228632 |
| 28 | Lactic acidosis (HP:0003128) | 2.87317673 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.79275070 |
| 30 | Hyperglycinemia (HP:0002154) | 2.74032571 |
| 31 | Respiratory failure (HP:0002878) | 2.70719536 |
| 32 | Pancreatic cysts (HP:0001737) | 2.70450563 |
| 33 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.68265008 |
| 34 | Optic disc pallor (HP:0000543) | 2.63747385 |
| 35 | Increased IgM level (HP:0003496) | 2.61809856 |
| 36 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.54191341 |
| 37 | Lethargy (HP:0001254) | 2.54135693 |
| 38 | Methylmalonic aciduria (HP:0012120) | 2.53282371 |
| 39 | Autoimmune hemolytic anemia (HP:0001890) | 2.52042705 |
| 40 | Colon cancer (HP:0003003) | 2.51510997 |
| 41 | Increased muscle lipid content (HP:0009058) | 2.51497846 |
| 42 | Exertional dyspnea (HP:0002875) | 2.51203631 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49993430 |
| 44 | Methylmalonic acidemia (HP:0002912) | 2.45011039 |
| 45 | Generalized aminoaciduria (HP:0002909) | 2.44829969 |
| 46 | Combined immunodeficiency (HP:0005387) | 2.44530972 |
| 47 | Exercise intolerance (HP:0003546) | 2.43003592 |
| 48 | Oral leukoplakia (HP:0002745) | 2.38394066 |
| 49 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.38042570 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.36635615 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.36635615 |
| 52 | Reduced antithrombin III activity (HP:0001976) | 2.33983870 |
| 53 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.33212460 |
| 54 | Abnormality of eosinophils (HP:0001879) | 2.31686055 |
| 55 | Pancreatic fibrosis (HP:0100732) | 2.31411272 |
| 56 | Congenital, generalized hypertrichosis (HP:0004540) | 2.31197968 |
| 57 | Autoimmune thrombocytopenia (HP:0001973) | 2.25342877 |
| 58 | True hermaphroditism (HP:0010459) | 2.22236539 |
| 59 | Type I transferrin isoform profile (HP:0003642) | 2.20786646 |
| 60 | Abnormality of T cells (HP:0002843) | 2.18394379 |
| 61 | Eosinophilia (HP:0001880) | 2.17299273 |
| 62 | Leukodystrophy (HP:0002415) | 2.15042105 |
| 63 | B lymphocytopenia (HP:0010976) | 2.11231070 |
| 64 | Thyroiditis (HP:0100646) | 2.09214039 |
| 65 | Abnormality of serum amino acid levels (HP:0003112) | 2.05981074 |
| 66 | Pendular nystagmus (HP:0012043) | 2.04684216 |
| 67 | Abnormality of the renal cortex (HP:0011035) | 2.03347083 |
| 68 | Dicarboxylic aciduria (HP:0003215) | 2.02160199 |
| 69 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.02160199 |
| 70 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.96571061 |
| 71 | Abnormality of glycine metabolism (HP:0010895) | 1.96571061 |
| 72 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.94678996 |
| 73 | Stomach cancer (HP:0012126) | 1.93039081 |
| 74 | Abnormality of renal resorption (HP:0011038) | 1.91054775 |
| 75 | CNS demyelination (HP:0007305) | 1.89685176 |
| 76 | Hyperphosphaturia (HP:0003109) | 1.88023655 |
| 77 | Constricted visual fields (HP:0001133) | 1.87610851 |
| 78 | Attenuation of retinal blood vessels (HP:0007843) | 1.86426085 |
| 79 | Glycosuria (HP:0003076) | 1.85637508 |
| 80 | Abnormality of urine glucose concentration (HP:0011016) | 1.85637508 |
| 81 | Neonatal respiratory distress (HP:0002643) | 1.84828689 |
| 82 | Renal cortical cysts (HP:0000803) | 1.84450611 |
| 83 | Opisthotonus (HP:0002179) | 1.81276629 |
| 84 | Abnormality of the prostate (HP:0008775) | 1.81093063 |
| 85 | Delayed CNS myelination (HP:0002188) | 1.79711047 |
| 86 | Granulocytopenia (HP:0001913) | 1.78113383 |
| 87 | Abnormality of the ileum (HP:0001549) | 1.75535845 |
| 88 | Reticulocytopenia (HP:0001896) | 1.75322983 |
| 89 | Emotional lability (HP:0000712) | 1.73311170 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.72615935 |
| 91 | Hyperalaninemia (HP:0003348) | 1.72615935 |
| 92 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.72615935 |
| 93 | Respiratory difficulties (HP:0002880) | 1.72338772 |
| 94 | Meckel diverticulum (HP:0002245) | 1.71087620 |
| 95 | Bile duct proliferation (HP:0001408) | 1.68697444 |
| 96 | Abnormal biliary tract physiology (HP:0012439) | 1.68697444 |
| 97 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.68161055 |
| 98 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.68161055 |
| 99 | Abnormal protein glycosylation (HP:0012346) | 1.68161055 |
| 100 | Abnormal glycosylation (HP:0012345) | 1.68161055 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 3.98105994 |
| 2 | VRK2 | 3.72895673 |
| 3 | TESK2 | 3.60610731 |
| 4 | TXK | 3.57578322 |
| 5 | ZAK | 3.15065956 |
| 6 | STK16 | 2.68855638 |
| 7 | MAP4K2 | 2.61801322 |
| 8 | BUB1 | 2.61118726 |
| 9 | TLK1 | 2.55874004 |
| 10 | BCKDK | 2.48842079 |
| 11 | TAOK3 | 2.15016748 |
| 12 | VRK1 | 2.13931013 |
| 13 | MST4 | 1.92510428 |
| 14 | LIMK1 | 1.84583097 |
| 15 | MAP3K12 | 1.82794539 |
| 16 | TESK1 | 1.82457215 |
| 17 | ADRBK2 | 1.82018078 |
| 18 | NUAK1 | 1.73267205 |
| 19 | GRK1 | 1.62037733 |
| 20 | NEK1 | 1.53385114 |
| 21 | SRPK1 | 1.47622119 |
| 22 | EIF2AK3 | 1.43684922 |
| 23 | TIE1 | 1.41733718 |
| 24 | MAP4K1 | 1.39336813 |
| 25 | NME1 | 1.38533202 |
| 26 | CSNK1G3 | 1.30811667 |
| 27 | PASK | 1.29173836 |
| 28 | PINK1 | 1.24794118 |
| 29 | GRK6 | 1.21317552 |
| 30 | DAPK1 | 1.20596312 |
| 31 | MAP3K11 | 1.19148994 |
| 32 | WNK4 | 1.16763086 |
| 33 | BCR | 1.11350160 |
| 34 | OXSR1 | 1.05238269 |
| 35 | CSNK1A1L | 1.02855000 |
| 36 | MYLK | 1.02259703 |
| 37 | CSNK1G1 | 0.96848283 |
| 38 | TRIM28 | 0.95485380 |
| 39 | ITK | 0.95457762 |
| 40 | CSNK1G2 | 0.94666093 |
| 41 | DYRK2 | 0.94467930 |
| 42 | MAPKAPK3 | 0.87738048 |
| 43 | INSRR | 0.86953345 |
| 44 | MAP2K7 | 0.86798571 |
| 45 | WNK3 | 0.85124669 |
| 46 | CDC7 | 0.83753936 |
| 47 | TEC | 0.83727437 |
| 48 | EIF2AK1 | 0.83556453 |
| 49 | STK39 | 0.83034516 |
| 50 | SCYL2 | 0.81285584 |
| 51 | PBK | 0.79392607 |
| 52 | TSSK6 | 0.76872742 |
| 53 | PLK4 | 0.75205966 |
| 54 | PLK2 | 0.75130011 |
| 55 | SYK | 0.75002022 |
| 56 | PLK3 | 0.74748298 |
| 57 | PRKCQ | 0.73194763 |
| 58 | MUSK | 0.68852503 |
| 59 | CDK19 | 0.68307562 |
| 60 | FRK | 0.67898917 |
| 61 | PIM2 | 0.63232562 |
| 62 | RPS6KA5 | 0.61368760 |
| 63 | CDK8 | 0.57226179 |
| 64 | PLK1 | 0.57101276 |
| 65 | ERBB3 | 0.56312490 |
| 66 | AURKA | 0.55741525 |
| 67 | PIK3CG | 0.55317489 |
| 68 | CAMKK2 | 0.53463712 |
| 69 | AURKB | 0.52990564 |
| 70 | IKBKE | 0.52941736 |
| 71 | PHKG2 | 0.52887159 |
| 72 | PHKG1 | 0.52887159 |
| 73 | IKBKB | 0.51834811 |
| 74 | BTK | 0.51431322 |
| 75 | GRK7 | 0.50913248 |
| 76 | LCK | 0.49161443 |
| 77 | TNK2 | 0.48709039 |
| 78 | CSNK2A1 | 0.46955036 |
| 79 | CLK1 | 0.46258072 |
| 80 | LMTK2 | 0.45860732 |
| 81 | ADRBK1 | 0.45320532 |
| 82 | GRK5 | 0.44977617 |
| 83 | LYN | 0.42932363 |
| 84 | ATR | 0.41626731 |
| 85 | MAP2K6 | 0.41053273 |
| 86 | MAPK13 | 0.40922101 |
| 87 | CSNK2A2 | 0.39900725 |
| 88 | TAF1 | 0.39485331 |
| 89 | FES | 0.38390364 |
| 90 | IGF1R | 0.37959970 |
| 91 | BMPR1B | 0.36688238 |
| 92 | ABL2 | 0.35514109 |
| 93 | ZAP70 | 0.34380153 |
| 94 | EIF2AK2 | 0.34014049 |
| 95 | DAPK3 | 0.33583577 |
| 96 | WEE1 | 0.33069537 |
| 97 | CAMKK1 | 0.32931269 |
| 98 | PRKCE | 0.32010180 |
| 99 | KIT | 0.31722650 |
| 100 | PRKACA | 0.30066301 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.39737673 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.01287081 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46588573 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.94738351 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.91067463 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.71480906 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.27602480 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.23027021 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.16120224 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.14504209 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.08054598 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.92856534 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.86807679 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.83620942 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.80918310 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.71947632 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.70227613 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.64892827 |
| 19 | Base excision repair_Homo sapiens_hsa03410 | 1.60295506 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.60244570 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.51717798 |
| 22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.51081888 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.48189234 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44028328 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.35157032 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.30451855 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.29960564 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.28470110 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.27154330 |
| 30 | Allograft rejection_Homo sapiens_hsa05330 | 1.26997019 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.26601294 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.24927231 |
| 33 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.20436973 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.14083137 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.10351271 |
| 36 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.10083015 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.06254291 |
| 38 | Asthma_Homo sapiens_hsa05310 | 1.03718953 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.02749738 |
| 40 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.00172678 |
| 41 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.95334861 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93655326 |
| 43 | Phototransduction_Homo sapiens_hsa04744 | 0.92772967 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 0.92638452 |
| 45 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.91972530 |
| 46 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.91256716 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.88514382 |
| 48 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87406007 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.86428761 |
| 50 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.86055351 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85006233 |
| 52 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.84756899 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83576472 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83045789 |
| 55 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82092972 |
| 56 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.80900297 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.80557864 |
| 58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.77225295 |
| 59 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74405568 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.73185980 |
| 61 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.72338731 |
| 62 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.71830387 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71822511 |
| 64 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.71297734 |
| 65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.71133348 |
| 66 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.67556699 |
| 67 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.67064212 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.66525944 |
| 69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.65738187 |
| 70 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.64310025 |
| 71 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.63288668 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.61337277 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59574298 |
| 74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58802902 |
| 75 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.57139901 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55156730 |
| 77 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.54723306 |
| 78 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51868249 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49190425 |
| 80 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47079792 |
| 81 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.47005465 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46805775 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46407789 |
| 84 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.44916104 |
| 85 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.44407674 |
| 86 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.41931264 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.41384055 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.41073678 |
| 89 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40529627 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38504322 |
| 91 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38211073 |
| 92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.37824585 |
| 93 | Shigellosis_Homo sapiens_hsa05131 | 0.36808681 |
| 94 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.34511630 |
| 95 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.33972374 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.33168333 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32316532 |
| 98 | Olfactory transduction_Homo sapiens_hsa04740 | 0.30018760 |
| 99 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.29347119 |
| 100 | Viral myocarditis_Homo sapiens_hsa05416 | 0.28009733 |

