

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.93144713 |
| 2 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.89290999 |
| 3 | DNA deamination (GO:0045006) | 4.77568545 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.30139517 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.30139517 |
| 6 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.25031690 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.25031690 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.22844423 |
| 9 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.20289871 |
| 10 | chromatin remodeling at centromere (GO:0031055) | 4.12917817 |
| 11 | CENP-A containing nucleosome assembly (GO:0034080) | 4.12027313 |
| 12 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.06303837 |
| 13 | DNA replication checkpoint (GO:0000076) | 3.95850515 |
| 14 | piRNA metabolic process (GO:0034587) | 3.95489785 |
| 15 | regulation of meiosis I (GO:0060631) | 3.91594018 |
| 16 | cullin deneddylation (GO:0010388) | 3.90906865 |
| 17 | protein deneddylation (GO:0000338) | 3.90664169 |
| 18 | chaperone-mediated protein transport (GO:0072321) | 3.89652046 |
| 19 | base-excision repair, AP site formation (GO:0006285) | 3.87170898 |
| 20 | multicellular organism reproduction (GO:0032504) | 3.85630057 |
| 21 | regulation of acrosome reaction (GO:0060046) | 3.78871375 |
| 22 | regulation of DNA methylation (GO:0044030) | 3.68655303 |
| 23 | meiotic cell cycle (GO:0051321) | 3.61318980 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.60000812 |
| 25 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.59045574 |
| 26 | retinal cone cell development (GO:0046549) | 3.58335684 |
| 27 | replication fork processing (GO:0031297) | 3.54156216 |
| 28 | respiratory electron transport chain (GO:0022904) | 3.50349550 |
| 29 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.47023082 |
| 30 | NADH dehydrogenase complex assembly (GO:0010257) | 3.47023082 |
| 31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.47023082 |
| 32 | electron transport chain (GO:0022900) | 3.46528640 |
| 33 | protein neddylation (GO:0045116) | 3.45112378 |
| 34 | maturation of SSU-rRNA (GO:0030490) | 3.43698345 |
| 35 | behavioral response to nicotine (GO:0035095) | 3.43311698 |
| 36 | protein complex biogenesis (GO:0070271) | 3.39367809 |
| 37 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.37544498 |
| 38 | histone exchange (GO:0043486) | 3.36193582 |
| 39 | negative regulation of telomere maintenance (GO:0032205) | 3.35147928 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.33024874 |
| 41 | viral transcription (GO:0019083) | 3.30310801 |
| 42 | pseudouridine synthesis (GO:0001522) | 3.29963638 |
| 43 | translational termination (GO:0006415) | 3.29689462 |
| 44 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.26575394 |
| 45 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.25820079 |
| 46 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.22046007 |
| 47 | termination of RNA polymerase III transcription (GO:0006386) | 3.22046007 |
| 48 | epithelial cilium movement (GO:0003351) | 3.20950015 |
| 49 | ribosomal small subunit biogenesis (GO:0042274) | 3.20840899 |
| 50 | proteasome assembly (GO:0043248) | 3.20215798 |
| 51 | ribosomal large subunit biogenesis (GO:0042273) | 3.18706859 |
| 52 | male meiosis I (GO:0007141) | 3.14547699 |
| 53 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.11652524 |
| 54 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.10817958 |
| 55 | cotranslational protein targeting to membrane (GO:0006613) | 3.04771338 |
| 56 | peptidyl-histidine modification (GO:0018202) | 3.04498477 |
| 57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.03964900 |
| 58 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.03563445 |
| 59 | protein targeting to ER (GO:0045047) | 3.01613326 |
| 60 | translational elongation (GO:0006414) | 3.01305249 |
| 61 | cytidine metabolic process (GO:0046087) | 2.94501794 |
| 62 | cytidine catabolic process (GO:0006216) | 2.94501794 |
| 63 | cytidine deamination (GO:0009972) | 2.94501794 |
| 64 | deoxyribonucleotide catabolic process (GO:0009264) | 2.94265330 |
| 65 | DNA replication-independent nucleosome organization (GO:0034724) | 2.91974235 |
| 66 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.91974235 |
| 67 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.90319320 |
| 68 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 2.90000282 |
| 69 | oocyte development (GO:0048599) | 2.89291563 |
| 70 | respiratory chain complex IV assembly (GO:0008535) | 2.88947373 |
| 71 | cellular component biogenesis (GO:0044085) | 2.86793946 |
| 72 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.86065567 |
| 73 | protein localization to endoplasmic reticulum (GO:0070972) | 2.85121209 |
| 74 | protein polyglutamylation (GO:0018095) | 2.84816964 |
| 75 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.84706812 |
| 76 | maturation of 5.8S rRNA (GO:0000460) | 2.81669321 |
| 77 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.81355019 |
| 78 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.81352975 |
| 79 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.79919620 |
| 80 | regulation of female gonad development (GO:2000194) | 2.79107129 |
| 81 | rRNA processing (GO:0006364) | 2.77851609 |
| 82 | translation (GO:0006412) | 2.77366237 |
| 83 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.77271488 |
| 84 | ncRNA 3-end processing (GO:0043628) | 2.77005053 |
| 85 | DNA methylation involved in gamete generation (GO:0043046) | 2.76889780 |
| 86 | hydrogen ion transmembrane transport (GO:1902600) | 2.76583040 |
| 87 | regulation of oxidative phosphorylation (GO:0002082) | 2.76073434 |
| 88 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.75434793 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.75320561 |
| 90 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.74251531 |
| 91 | translational initiation (GO:0006413) | 2.73953228 |
| 92 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.73106619 |
| 93 | deoxyribose phosphate catabolic process (GO:0046386) | 2.72252276 |
| 94 | rRNA metabolic process (GO:0016072) | 2.71431811 |
| 95 | meiosis I (GO:0007127) | 2.71223462 |
| 96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.70562641 |
| 97 | centriole replication (GO:0007099) | 2.67918671 |
| 98 | GTP biosynthetic process (GO:0006183) | 2.67377617 |
| 99 | ribosome biogenesis (GO:0042254) | 2.66663990 |
| 100 | cilium movement (GO:0003341) | 2.65769414 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.41769259 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.07531523 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.02439316 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.25967655 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.06069923 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.93256915 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.82503754 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49445648 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.48628083 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.43813411 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.35709717 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.35100152 |
| 13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.25873192 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.22551021 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.14292350 |
| 16 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.11871938 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.10261021 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.08515198 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.08009465 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06268285 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.06078276 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.04178546 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.91631865 |
| 24 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.83486422 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.82284048 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.76909996 |
| 27 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.75902667 |
| 28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.73213135 |
| 29 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.71037364 |
| 30 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.70210975 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68669108 |
| 32 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.63152118 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.60482417 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.59695990 |
| 35 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.56577457 |
| 36 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.56233620 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.56144663 |
| 38 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.51359307 |
| 39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49756794 |
| 40 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.45727844 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.44274761 |
| 42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.43568634 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42351264 |
| 44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40792222 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33216070 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.32000556 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.30692735 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30149060 |
| 49 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.27741653 |
| 50 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.26316369 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25564887 |
| 52 | P300_19829295_ChIP-Seq_ESCs_Human | 1.24296442 |
| 53 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.22618738 |
| 54 | AR_20517297_ChIP-Seq_VCAP_Human | 1.21714685 |
| 55 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.20944336 |
| 56 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.20001595 |
| 57 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.17688662 |
| 58 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17001299 |
| 59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16125277 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.15858008 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.15842302 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.15842302 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14215185 |
| 64 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.14128735 |
| 65 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13165551 |
| 66 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13089850 |
| 67 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.11405937 |
| 68 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.10761991 |
| 69 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.09272655 |
| 70 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.09252444 |
| 71 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07561767 |
| 72 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07049087 |
| 73 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.06420099 |
| 74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.06420099 |
| 75 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.06160981 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06142318 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 1.06030588 |
| 78 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.01491766 |
| 79 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.99711609 |
| 80 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.99641625 |
| 81 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97171765 |
| 82 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97171765 |
| 83 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96645096 |
| 84 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.96506481 |
| 85 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.95706598 |
| 86 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93349726 |
| 87 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92830355 |
| 88 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.92431325 |
| 89 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.91763123 |
| 90 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.89887757 |
| 91 | ERA_21632823_ChIP-Seq_H3396_Human | 0.88478589 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87910799 |
| 93 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87793124 |
| 94 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.87529400 |
| 95 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.86891722 |
| 96 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.86520403 |
| 97 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86482469 |
| 98 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.86448605 |
| 99 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.85858189 |
| 100 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85500117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.89868356 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.85574458 |
| 3 | MP0003718_maternal_effect | 3.35460564 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.11516698 |
| 5 | MP0003890_abnormal_embryonic-extraembry | 3.08059424 |
| 6 | MP0002102_abnormal_ear_morphology | 2.95742032 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.92700392 |
| 8 | MP0008058_abnormal_DNA_repair | 2.64669713 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.43068863 |
| 10 | MP0006276_abnormal_autonomic_nervous | 2.22446829 |
| 11 | MP0008789_abnormal_olfactory_epithelium | 2.20928959 |
| 12 | MP0006054_spinal_hemorrhage | 2.09738308 |
| 13 | MP0001986_abnormal_taste_sensitivity | 2.01380393 |
| 14 | MP0005394_taste/olfaction_phenotype | 1.92804506 |
| 15 | MP0005499_abnormal_olfactory_system | 1.92804506 |
| 16 | MP0001293_anophthalmia | 1.85162288 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.84870054 |
| 18 | MP0004142_abnormal_muscle_tone | 1.74695800 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.73095496 |
| 20 | MP0002272_abnormal_nervous_system | 1.71218740 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.62963897 |
| 22 | MP0010094_abnormal_chromosome_stability | 1.62712144 |
| 23 | MP0002160_abnormal_reproductive_system | 1.62564384 |
| 24 | MP0005084_abnormal_gallbladder_morpholo | 1.56759782 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.56022488 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.55323933 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.54159243 |
| 28 | MP0003121_genomic_imprinting | 1.47904762 |
| 29 | MP0002210_abnormal_sex_determination | 1.43202037 |
| 30 | MP0002876_abnormal_thyroid_physiology | 1.42937351 |
| 31 | MP0003283_abnormal_digestive_organ | 1.42312634 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.39471544 |
| 33 | MP0005389_reproductive_system_phenotype | 1.39075001 |
| 34 | MP0001929_abnormal_gametogenesis | 1.38987285 |
| 35 | MP0004957_abnormal_blastocyst_morpholog | 1.34520220 |
| 36 | MP0003950_abnormal_plasma_membrane | 1.34007468 |
| 37 | MP0004147_increased_porphyrin_level | 1.32131358 |
| 38 | MP0008932_abnormal_embryonic_tissue | 1.32113839 |
| 39 | MP0001984_abnormal_olfaction | 1.29987413 |
| 40 | MP0001529_abnormal_vocalization | 1.29059116 |
| 41 | MP0003786_premature_aging | 1.27155615 |
| 42 | MP0003186_abnormal_redox_activity | 1.25571578 |
| 43 | MP0000631_abnormal_neuroendocrine_gland | 1.23547114 |
| 44 | MP0005410_abnormal_fertilization | 1.23180157 |
| 45 | MP0006036_abnormal_mitochondrial_physio | 1.22983525 |
| 46 | MP0003077_abnormal_cell_cycle | 1.22520131 |
| 47 | MP0003806_abnormal_nucleotide_metabolis | 1.22367443 |
| 48 | MP0002163_abnormal_gland_morphology | 1.21611973 |
| 49 | MP0005174_abnormal_tail_pigmentation | 1.19137683 |
| 50 | MP0008872_abnormal_physiological_respon | 1.18086068 |
| 51 | MP0003787_abnormal_imprinting | 1.16233315 |
| 52 | MP0005075_abnormal_melanosome_morpholog | 1.13707092 |
| 53 | MP0000427_abnormal_hair_cycle | 1.12405661 |
| 54 | MP0002638_abnormal_pupillary_reflex | 1.08601732 |
| 55 | MP0002277_abnormal_respiratory_mucosa | 1.08022738 |
| 56 | MP0009745_abnormal_behavioral_response | 1.07177138 |
| 57 | MP0000653_abnormal_sex_gland | 1.07136125 |
| 58 | MP0001485_abnormal_pinna_reflex | 1.05820010 |
| 59 | MP0000049_abnormal_middle_ear | 1.05432735 |
| 60 | MP0002095_abnormal_skin_pigmentation | 1.03498775 |
| 61 | MP0005360_urolithiasis | 1.03117227 |
| 62 | MP0002938_white_spotting | 1.02900892 |
| 63 | MP0002733_abnormal_thermal_nociception | 1.02415574 |
| 64 | MP0001968_abnormal_touch/_nociception | 1.00561979 |
| 65 | MP0005085_abnormal_gallbladder_physiolo | 1.00277868 |
| 66 | MP0003699_abnormal_female_reproductive | 0.98215183 |
| 67 | MP0001905_abnormal_dopamine_level | 0.97091423 |
| 68 | MP0001119_abnormal_female_reproductive | 0.95763770 |
| 69 | MP0004133_heterotaxia | 0.94998580 |
| 70 | MP0006035_abnormal_mitochondrial_morpho | 0.94468503 |
| 71 | MP0002734_abnormal_mechanical_nocicepti | 0.94356693 |
| 72 | MP0003119_abnormal_digestive_system | 0.92977708 |
| 73 | MP0003936_abnormal_reproductive_system | 0.92674867 |
| 74 | MP0000015_abnormal_ear_pigmentation | 0.92055568 |
| 75 | MP0003880_abnormal_central_pattern | 0.91670123 |
| 76 | MP0001145_abnormal_male_reproductive | 0.89776874 |
| 77 | MP0002735_abnormal_chemical_nociception | 0.88184961 |
| 78 | MP0003698_abnormal_male_reproductive | 0.87151349 |
| 79 | MP0005423_abnormal_somatic_nervous | 0.86788665 |
| 80 | MP0003252_abnormal_bile_duct | 0.85526699 |
| 81 | MP0002161_abnormal_fertility/fecundity | 0.85211957 |
| 82 | MP0004270_analgesia | 0.84289592 |
| 83 | MP0003879_abnormal_hair_cell | 0.83714841 |
| 84 | MP0000778_abnormal_nervous_system | 0.82329889 |
| 85 | MP0005395_other_phenotype | 0.80962836 |
| 86 | MP0002557_abnormal_social/conspecific_i | 0.80853449 |
| 87 | MP0005195_abnormal_posterior_eye | 0.79220776 |
| 88 | MP0003635_abnormal_synaptic_transmissio | 0.79218353 |
| 89 | MP0002139_abnormal_hepatobiliary_system | 0.77700334 |
| 90 | MP0002837_dystrophic_cardiac_calcinosis | 0.77352320 |
| 91 | MP0003938_abnormal_ear_development | 0.77133584 |
| 92 | MP0002736_abnormal_nociception_after | 0.76446401 |
| 93 | MP0002090_abnormal_vision | 0.76192274 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.75414154 |
| 95 | MP0002751_abnormal_autonomic_nervous | 0.74881945 |
| 96 | MP0001970_abnormal_pain_threshold | 0.74181412 |
| 97 | MP0003011_delayed_dark_adaptation | 0.73906409 |
| 98 | MP0002063_abnormal_learning/memory/cond | 0.73501274 |
| 99 | MP0009046_muscle_twitch | 0.73359540 |
| 100 | MP0010386_abnormal_urinary_bladder | 0.73235037 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Supernumerary spleens (HP:0009799) | 4.75050163 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.58968725 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.91332780 |
| 4 | Acute encephalopathy (HP:0006846) | 3.88113029 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.66563378 |
| 6 | Reticulocytopenia (HP:0001896) | 3.47082034 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.45884949 |
| 8 | Increased CSF lactate (HP:0002490) | 3.31551851 |
| 9 | Aplastic anemia (HP:0001915) | 3.30649508 |
| 10 | Abnormality of the labia minora (HP:0012880) | 3.18006181 |
| 11 | Abdominal situs inversus (HP:0003363) | 3.01988566 |
| 12 | Abnormality of abdominal situs (HP:0011620) | 3.01988566 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.01772506 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 3.01772506 |
| 15 | Cerebral edema (HP:0002181) | 2.71919181 |
| 16 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.64980784 |
| 17 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.64980784 |
| 18 | Absent thumb (HP:0009777) | 2.64490554 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 2.62464549 |
| 20 | Pancreatic fibrosis (HP:0100732) | 2.62160475 |
| 21 | Stenosis of the external auditory canal (HP:0000402) | 2.61267902 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.59261380 |
| 23 | Pancreatic cysts (HP:0001737) | 2.57527343 |
| 24 | Abnormal ciliary motility (HP:0012262) | 2.51492084 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 2.50900459 |
| 26 | Increased serum lactate (HP:0002151) | 2.50142161 |
| 27 | Chromsome breakage (HP:0040012) | 2.48496033 |
| 28 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.46607461 |
| 29 | Medial flaring of the eyebrow (HP:0010747) | 2.43611583 |
| 30 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.41273439 |
| 31 | Hepatic necrosis (HP:0002605) | 2.38557328 |
| 32 | Premature ovarian failure (HP:0008209) | 2.36855548 |
| 33 | Optic disc pallor (HP:0000543) | 2.36740961 |
| 34 | Myokymia (HP:0002411) | 2.36341939 |
| 35 | Hepatocellular necrosis (HP:0001404) | 2.36281614 |
| 36 | Short tibia (HP:0005736) | 2.32388085 |
| 37 | Oligodactyly (hands) (HP:0001180) | 2.29661822 |
| 38 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.29595989 |
| 39 | Gonadotropin excess (HP:0000837) | 2.28748866 |
| 40 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.28402541 |
| 41 | 3-Methylglutaconic aciduria (HP:0003535) | 2.28234784 |
| 42 | Adrenal hypoplasia (HP:0000835) | 2.25792749 |
| 43 | Hypophosphatemic rickets (HP:0004912) | 2.19031753 |
| 44 | Macrocytic anemia (HP:0001972) | 2.17981431 |
| 45 | Septo-optic dysplasia (HP:0100842) | 2.17977950 |
| 46 | Meckel diverticulum (HP:0002245) | 2.17672328 |
| 47 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.14539978 |
| 48 | Asplenia (HP:0001746) | 2.14311160 |
| 49 | Exertional dyspnea (HP:0002875) | 2.10150879 |
| 50 | Abnormality of the ileum (HP:0001549) | 2.09198996 |
| 51 | Median cleft lip (HP:0000161) | 2.08614378 |
| 52 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.08486683 |
| 53 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.07954979 |
| 54 | Absent/shortened dynein arms (HP:0200106) | 2.07954979 |
| 55 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.05697240 |
| 56 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.03936986 |
| 57 | Lactic acidosis (HP:0003128) | 2.02135899 |
| 58 | Sclerocornea (HP:0000647) | 2.01523365 |
| 59 | Posterior subcapsular cataract (HP:0007787) | 1.97508302 |
| 60 | Absent septum pellucidum (HP:0001331) | 1.96328972 |
| 61 | Congenital malformation of the right heart (HP:0011723) | 1.96292624 |
| 62 | Double outlet right ventricle (HP:0001719) | 1.96292624 |
| 63 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.95383824 |
| 64 | Hypoplasia of the fovea (HP:0007750) | 1.95383824 |
| 65 | Limb hypertonia (HP:0002509) | 1.95311773 |
| 66 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.95069013 |
| 67 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.94271153 |
| 68 | Abnormality of chromosome stability (HP:0003220) | 1.92945549 |
| 69 | Pancytopenia (HP:0001876) | 1.92695239 |
| 70 | Glycosuria (HP:0003076) | 1.91829023 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.91829023 |
| 72 | Methylmalonic acidemia (HP:0002912) | 1.90307517 |
| 73 | Lethargy (HP:0001254) | 1.89726653 |
| 74 | Nephronophthisis (HP:0000090) | 1.89651331 |
| 75 | Exercise intolerance (HP:0003546) | 1.89026240 |
| 76 | Abnormality of the anterior horn cell (HP:0006802) | 1.88964431 |
| 77 | Degeneration of anterior horn cells (HP:0002398) | 1.88964431 |
| 78 | Abnormality of dental color (HP:0011073) | 1.88778025 |
| 79 | Sensory axonal neuropathy (HP:0003390) | 1.87219705 |
| 80 | X-linked dominant inheritance (HP:0001423) | 1.86857984 |
| 81 | Gait imbalance (HP:0002141) | 1.86578791 |
| 82 | Colon cancer (HP:0003003) | 1.85351718 |
| 83 | Increased intramyocellular lipid droplets (HP:0012240) | 1.84874724 |
| 84 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.84748823 |
| 85 | Infertility (HP:0000789) | 1.84477769 |
| 86 | Horseshoe kidney (HP:0000085) | 1.84447895 |
| 87 | True hermaphroditism (HP:0010459) | 1.83873727 |
| 88 | Impulsivity (HP:0100710) | 1.82277730 |
| 89 | Respiratory failure (HP:0002878) | 1.80216819 |
| 90 | Pendular nystagmus (HP:0012043) | 1.78802304 |
| 91 | Oligodactyly (HP:0012165) | 1.78799849 |
| 92 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78752426 |
| 93 | Rhinitis (HP:0012384) | 1.77811476 |
| 94 | Progressive inability to walk (HP:0002505) | 1.74309405 |
| 95 | Leukodystrophy (HP:0002415) | 1.74278970 |
| 96 | Parakeratosis (HP:0001036) | 1.74032063 |
| 97 | Increased serum pyruvate (HP:0003542) | 1.73300743 |
| 98 | Congenital stationary night blindness (HP:0007642) | 1.72825471 |
| 99 | Abnormality of the preputium (HP:0100587) | 1.72743556 |
| 100 | Hyperalaninemia (HP:0003348) | 1.72539591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 3.31399570 |
| 2 | WNK4 | 2.87331588 |
| 3 | PLK4 | 2.64506478 |
| 4 | STK39 | 2.61092433 |
| 5 | TRIM28 | 2.54383336 |
| 6 | MAP3K9 | 2.44672122 |
| 7 | ZAK | 2.33311127 |
| 8 | MAP3K12 | 2.30758747 |
| 9 | TSSK6 | 2.28352911 |
| 10 | TLK1 | 2.17362138 |
| 11 | GRK1 | 2.02991883 |
| 12 | BCKDK | 2.00122984 |
| 13 | VRK2 | 1.93269913 |
| 14 | TAOK3 | 1.92720276 |
| 15 | SRPK1 | 1.92343187 |
| 16 | STK16 | 1.90916341 |
| 17 | NUAK1 | 1.85130219 |
| 18 | PDK2 | 1.75386324 |
| 19 | ADRBK2 | 1.59332729 |
| 20 | WNK3 | 1.59153809 |
| 21 | BUB1 | 1.57386642 |
| 22 | LIMK1 | 1.52838748 |
| 23 | DYRK2 | 1.47128466 |
| 24 | INSRR | 1.46295708 |
| 25 | CDK19 | 1.43871531 |
| 26 | MAP4K2 | 1.43786403 |
| 27 | EIF2AK3 | 1.42309491 |
| 28 | CDC7 | 1.41175722 |
| 29 | ARAF | 1.38547344 |
| 30 | OXSR1 | 1.37631912 |
| 31 | PLK2 | 1.35405083 |
| 32 | NEK1 | 1.28482149 |
| 33 | STK24 | 1.27672711 |
| 34 | PLK3 | 1.26545535 |
| 35 | BMPR1B | 1.24457609 |
| 36 | AURKA | 1.23323651 |
| 37 | PLK1 | 1.21599954 |
| 38 | MAP2K6 | 1.17386634 |
| 39 | VRK1 | 1.13584238 |
| 40 | TNIK | 1.10855582 |
| 41 | TTK | 1.07330688 |
| 42 | MATK | 1.01772744 |
| 43 | LRRK2 | 0.96118358 |
| 44 | BRSK2 | 0.95881294 |
| 45 | CAMKK2 | 0.90622125 |
| 46 | STK38L | 0.88462654 |
| 47 | MAP3K4 | 0.88197804 |
| 48 | CSNK1G1 | 0.87783651 |
| 49 | MAPK13 | 0.87339904 |
| 50 | NTRK2 | 0.85429766 |
| 51 | MAP3K13 | 0.85202517 |
| 52 | MAP2K7 | 0.83040429 |
| 53 | PRKD3 | 0.82006511 |
| 54 | AURKB | 0.80822068 |
| 55 | CSNK1G3 | 0.80583789 |
| 56 | PIK3CA | 0.79926075 |
| 57 | BRAF | 0.78874364 |
| 58 | ATR | 0.77409098 |
| 59 | ABL2 | 0.76112379 |
| 60 | MKNK2 | 0.74648451 |
| 61 | PRKCI | 0.74594301 |
| 62 | PINK1 | 0.73991846 |
| 63 | CSNK1G2 | 0.73560461 |
| 64 | WEE1 | 0.72121134 |
| 65 | BRSK1 | 0.71487372 |
| 66 | KDR | 0.71460127 |
| 67 | PASK | 0.71452406 |
| 68 | WNK1 | 0.68747251 |
| 69 | PRKCG | 0.66277743 |
| 70 | CSNK1E | 0.65747087 |
| 71 | NTRK1 | 0.61795570 |
| 72 | CSNK1A1L | 0.58420071 |
| 73 | MOS | 0.57997194 |
| 74 | STK3 | 0.57312300 |
| 75 | NEK2 | 0.56455366 |
| 76 | CSNK2A2 | 0.55946026 |
| 77 | EIF2AK2 | 0.54573897 |
| 78 | BCR | 0.53018661 |
| 79 | TESK2 | 0.52685959 |
| 80 | TXK | 0.52089885 |
| 81 | FRK | 0.51465237 |
| 82 | NME1 | 0.50303699 |
| 83 | PAK3 | 0.49963505 |
| 84 | EIF2AK1 | 0.49298152 |
| 85 | PNCK | 0.49117390 |
| 86 | MINK1 | 0.48743199 |
| 87 | TIE1 | 0.47993968 |
| 88 | ADRBK1 | 0.46944283 |
| 89 | CSNK2A1 | 0.46804824 |
| 90 | PHKG1 | 0.46550078 |
| 91 | PHKG2 | 0.46550078 |
| 92 | PRKCE | 0.45964587 |
| 93 | DAPK1 | 0.45853685 |
| 94 | KSR1 | 0.43111776 |
| 95 | DYRK3 | 0.42983073 |
| 96 | PRKCQ | 0.42633602 |
| 97 | DAPK2 | 0.40705562 |
| 98 | PRKACA | 0.40350264 |
| 99 | PAK1 | 0.40155234 |
| 100 | CAMK2A | 0.39815489 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.44571108 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34541878 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.00951917 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.99725207 |
| 5 | Basal transcription factors_Homo sapiens_hsa03022 | 2.45131026 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.40461690 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.40396526 |
| 8 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.32377096 |
| 9 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.23622092 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.23042224 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.15216738 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.15035939 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 2.10778522 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.98395891 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.98219659 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.91569970 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.90003623 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.87974923 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.79916722 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.79426915 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.75629640 |
| 22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.71137466 |
| 23 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.70474954 |
| 24 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.68181576 |
| 25 | Base excision repair_Homo sapiens_hsa03410 | 1.65974137 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.54658277 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.50906589 |
| 28 | RNA transport_Homo sapiens_hsa03013 | 1.47453379 |
| 29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.42178925 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41898567 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.39473994 |
| 32 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.38645806 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.32377430 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.28312151 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26290226 |
| 36 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.26236897 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.22394576 |
| 38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.21939863 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.20193276 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 1.19623043 |
| 41 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.08824911 |
| 42 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.07964260 |
| 43 | Nicotine addiction_Homo sapiens_hsa05033 | 1.06994840 |
| 44 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.03857084 |
| 45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03626075 |
| 46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.02468346 |
| 47 | Spliceosome_Homo sapiens_hsa03040 | 1.02343170 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 1.01727953 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.00323355 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.98274840 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.97063173 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.94803937 |
| 53 | Cell cycle_Homo sapiens_hsa04110 | 0.92613441 |
| 54 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.87557976 |
| 55 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.81465554 |
| 56 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.81429422 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80692823 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.80276158 |
| 59 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.79880104 |
| 60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79733717 |
| 61 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.76843439 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.76108285 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.75613071 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.73264804 |
| 65 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.72345674 |
| 66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70985710 |
| 67 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70902109 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68006802 |
| 69 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.67143271 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67085628 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63700043 |
| 72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60405301 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60279369 |
| 74 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55210295 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54839870 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.54795114 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.54041666 |
| 78 | GABAergic synapse_Homo sapiens_hsa04727 | 0.52438471 |
| 79 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51244900 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49346847 |
| 81 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.48927373 |
| 82 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48810699 |
| 83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46807149 |
| 84 | Morphine addiction_Homo sapiens_hsa05032 | 0.45527824 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.43872605 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43660088 |
| 87 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.37933643 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36237079 |
| 89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.34608791 |
| 90 | Insulin secretion_Homo sapiens_hsa04911 | 0.32712471 |
| 91 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.32689168 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.30780685 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27212115 |
| 94 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.26224250 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.23651450 |
| 96 | Sulfur relay system_Homo sapiens_hsa04122 | 0.22746362 |
| 97 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.21777524 |
| 98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.19294114 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.18130654 |
| 100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17533749 |

