

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.68096167 |
| 2 | cullin deneddylation (GO:0010388) | 4.67965238 |
| 3 | DNA deamination (GO:0045006) | 4.66862714 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.47422593 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 4.45444894 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.45444894 |
| 7 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.41275469 |
| 8 | respiratory chain complex IV assembly (GO:0008535) | 4.37605583 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.22103822 |
| 10 | termination of RNA polymerase III transcription (GO:0006386) | 4.17006888 |
| 11 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.17006888 |
| 12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.12699072 |
| 13 | protein deneddylation (GO:0000338) | 4.08721425 |
| 14 | cytidine deamination (GO:0009972) | 4.06620295 |
| 15 | cytidine metabolic process (GO:0046087) | 4.06620295 |
| 16 | cytidine catabolic process (GO:0006216) | 4.06620295 |
| 17 | DNA damage response, detection of DNA damage (GO:0042769) | 4.06042217 |
| 18 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.04327757 |
| 19 | protein complex biogenesis (GO:0070271) | 4.00779238 |
| 20 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.97412115 |
| 21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.88844651 |
| 22 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.83030131 |
| 23 | cytochrome complex assembly (GO:0017004) | 3.78956701 |
| 24 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.78326021 |
| 25 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.78326021 |
| 26 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.77757950 |
| 27 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.77757950 |
| 28 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.77757950 |
| 29 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.72524148 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.69070018 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.66745337 |
| 32 | negative regulation of ligase activity (GO:0051352) | 3.66745337 |
| 33 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.64454403 |
| 34 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.61907217 |
| 35 | aldehyde catabolic process (GO:0046185) | 3.61107288 |
| 36 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.58526163 |
| 37 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.58526163 |
| 38 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.53398670 |
| 39 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.52846058 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.52846058 |
| 41 | electron transport chain (GO:0022900) | 3.51966789 |
| 42 | rRNA modification (GO:0000154) | 3.51054136 |
| 43 | respiratory electron transport chain (GO:0022904) | 3.50930324 |
| 44 | negative regulation of heart rate (GO:0010459) | 3.50902284 |
| 45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.50786895 |
| 46 | mannosylation (GO:0097502) | 3.42085464 |
| 47 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.41298214 |
| 48 | regulation of cellular respiration (GO:0043457) | 3.36473318 |
| 49 | regulation of immunoglobulin secretion (GO:0051023) | 3.33154744 |
| 50 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.32104746 |
| 51 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.32104746 |
| 52 | NADH dehydrogenase complex assembly (GO:0010257) | 3.32104746 |
| 53 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.27462149 |
| 54 | dicarboxylic acid catabolic process (GO:0043649) | 3.26331835 |
| 55 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.25203824 |
| 56 | chaperone-mediated protein transport (GO:0072321) | 3.23424817 |
| 57 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.20070736 |
| 58 | regulation of podosome assembly (GO:0071801) | 3.18278270 |
| 59 | branched-chain amino acid catabolic process (GO:0009083) | 3.14553317 |
| 60 | regulation of cellular amine metabolic process (GO:0033238) | 3.12501327 |
| 61 | oxidative demethylation (GO:0070989) | 3.06506320 |
| 62 | regulation of chronic inflammatory response (GO:0002676) | 3.05472552 |
| 63 | protein-cofactor linkage (GO:0018065) | 3.04416567 |
| 64 | ribosomal large subunit biogenesis (GO:0042273) | 3.01113453 |
| 65 | translation (GO:0006412) | 2.99057280 |
| 66 | negative regulation of mast cell activation (GO:0033004) | 2.98549579 |
| 67 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.96421915 |
| 68 | positive regulation of ligase activity (GO:0051351) | 2.95427964 |
| 69 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.95148162 |
| 70 | hydrogen ion transmembrane transport (GO:1902600) | 2.94906806 |
| 71 | rRNA methylation (GO:0031167) | 2.94333092 |
| 72 | proteasome assembly (GO:0043248) | 2.94196607 |
| 73 | regulation of meiosis I (GO:0060631) | 2.92004252 |
| 74 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.91601028 |
| 75 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.91601028 |
| 76 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.90809269 |
| 77 | cellular component biogenesis (GO:0044085) | 2.88312916 |
| 78 | regulation of triglyceride catabolic process (GO:0010896) | 2.88071708 |
| 79 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.87050821 |
| 80 | positive regulation of cell cycle arrest (GO:0071158) | 2.86159043 |
| 81 | S-adenosylmethionine metabolic process (GO:0046500) | 2.83010050 |
| 82 | negative regulation of acute inflammatory response (GO:0002674) | 2.79859136 |
| 83 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.78940417 |
| 84 | ribosomal small subunit biogenesis (GO:0042274) | 2.78382572 |
| 85 | cotranslational protein targeting to membrane (GO:0006613) | 2.76247514 |
| 86 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.75580759 |
| 87 | proton transport (GO:0015992) | 2.75467890 |
| 88 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.75031043 |
| 89 | positive regulation of granulocyte differentiation (GO:0030854) | 2.75029938 |
| 90 | behavioral response to nicotine (GO:0035095) | 2.74686737 |
| 91 | hydrogen transport (GO:0006818) | 2.72018838 |
| 92 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.71777751 |
| 93 | histone H2A ubiquitination (GO:0033522) | 2.71280597 |
| 94 | synaptic transmission, cholinergic (GO:0007271) | 2.70080106 |
| 95 | translational termination (GO:0006415) | 2.70029983 |
| 96 | ribosome assembly (GO:0042255) | 2.69989348 |
| 97 | amino acid salvage (GO:0043102) | 2.67826748 |
| 98 | L-methionine salvage (GO:0071267) | 2.67826748 |
| 99 | L-methionine biosynthetic process (GO:0071265) | 2.67826748 |
| 100 | protein targeting to ER (GO:0045047) | 2.67757917 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.70873582 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.44218694 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.82597097 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.72309666 |
| 5 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 4.44745232 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.97330760 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.35567279 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.26947294 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.07936112 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.89565814 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.88296365 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.68393835 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.59771559 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.49433855 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.46291657 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45110278 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.44301894 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.40829707 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11019129 |
| 20 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.03041479 |
| 21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.95304530 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90843625 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.84492579 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.76402715 |
| 25 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65302162 |
| 26 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.65124020 |
| 27 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.64829451 |
| 28 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.62374441 |
| 29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.60542800 |
| 30 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.60352670 |
| 31 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.60298470 |
| 32 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.58387182 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.55799822 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.51097602 |
| 35 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.45510988 |
| 36 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.42155425 |
| 37 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.40407437 |
| 38 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.38833611 |
| 39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.35397182 |
| 40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.35397182 |
| 41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.35064320 |
| 42 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33094390 |
| 43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.30685455 |
| 44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.30566095 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.30252042 |
| 46 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.29989243 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27918190 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27605421 |
| 49 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.27118644 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26377019 |
| 51 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.25920015 |
| 52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23586120 |
| 53 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.21064556 |
| 54 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.20178811 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.16665054 |
| 56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.15766059 |
| 57 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.12168266 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11366150 |
| 59 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11366150 |
| 60 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.08356264 |
| 61 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.07848040 |
| 62 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.05465138 |
| 63 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.04673207 |
| 64 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.00332376 |
| 65 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.99186426 |
| 66 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98735886 |
| 67 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98710519 |
| 68 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.97050304 |
| 69 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.95869973 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95860390 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94802166 |
| 72 | VDR_22108803_ChIP-Seq_LS180_Human | 0.94204220 |
| 73 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.91325902 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90401428 |
| 75 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89934350 |
| 76 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.89041837 |
| 77 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.88538430 |
| 78 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.87704516 |
| 79 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.87084560 |
| 80 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86540541 |
| 81 | EWS_26573619_Chip-Seq_HEK293_Human | 0.84971400 |
| 82 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.84747526 |
| 83 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.84036315 |
| 84 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.83740850 |
| 85 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.82387188 |
| 86 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.81830899 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81201551 |
| 88 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.79588182 |
| 89 | MYB_26560356_Chip-Seq_TH2_Human | 0.79336129 |
| 90 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.78239456 |
| 91 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.78224507 |
| 92 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.77397237 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.76890871 |
| 94 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.76144532 |
| 95 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.75635346 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.75601913 |
| 97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.75601913 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.75567105 |
| 99 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.75280065 |
| 100 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.75023372 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 5.60715770 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.85871813 |
| 3 | MP0009379_abnormal_foot_pigmentation | 3.81200727 |
| 4 | MP0004147_increased_porphyrin_level | 3.59759180 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 3.54007573 |
| 6 | MP0005360_urolithiasis | 3.32887064 |
| 7 | MP0000372_irregular_coat_pigmentation | 3.12027549 |
| 8 | MP0002163_abnormal_gland_morphology | 2.82114566 |
| 9 | MP0003718_maternal_effect | 2.65319627 |
| 10 | MP0001835_abnormal_antigen_presentation | 2.62736669 |
| 11 | MP0005671_abnormal_response_to | 2.51305204 |
| 12 | MP0001348_abnormal_lacrimal_gland | 2.49600597 |
| 13 | MP0001873_stomach_inflammation | 2.38954865 |
| 14 | MP0008872_abnormal_physiological_respon | 2.36065243 |
| 15 | MP0006082_CNS_inflammation | 2.00965087 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 1.98301845 |
| 17 | MP0005408_hypopigmentation | 1.97408656 |
| 18 | MP0005085_abnormal_gallbladder_physiolo | 1.96085250 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 1.95739192 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.94963810 |
| 21 | MP0003195_calcinosis | 1.86162762 |
| 22 | MP0002102_abnormal_ear_morphology | 1.82416274 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.80325867 |
| 24 | MP0002090_abnormal_vision | 1.76879853 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 1.73425265 |
| 26 | MP0009785_altered_susceptibility_to | 1.71410651 |
| 27 | MP0003880_abnormal_central_pattern | 1.64337818 |
| 28 | MP0009697_abnormal_copulation | 1.62850800 |
| 29 | MP0005174_abnormal_tail_pigmentation | 1.59931273 |
| 30 | MP0003786_premature_aging | 1.52428630 |
| 31 | MP0002234_abnormal_pharynx_morphology | 1.51556612 |
| 32 | MP0003186_abnormal_redox_activity | 1.49722050 |
| 33 | MP0002876_abnormal_thyroid_physiology | 1.48487231 |
| 34 | MP0005379_endocrine/exocrine_gland_phen | 1.47707909 |
| 35 | MP0005332_abnormal_amino_acid | 1.44828239 |
| 36 | MP0002653_abnormal_ependyma_morphology | 1.40491001 |
| 37 | MP0002166_altered_tumor_susceptibility | 1.40000889 |
| 38 | MP0003011_delayed_dark_adaptation | 1.38815465 |
| 39 | MP0005000_abnormal_immune_tolerance | 1.33672605 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.32743349 |
| 41 | MP0002006_tumorigenesis | 1.32507941 |
| 42 | MP0005075_abnormal_melanosome_morpholog | 1.27074930 |
| 43 | MP0002138_abnormal_hepatobiliary_system | 1.22493590 |
| 44 | MP0001800_abnormal_humoral_immune | 1.17370192 |
| 45 | MP0005365_abnormal_bile_salt | 1.08982404 |
| 46 | MP0003866_abnormal_defecation | 1.08030172 |
| 47 | MP0005636_abnormal_mineral_homeostasis | 1.07961355 |
| 48 | MP0001986_abnormal_taste_sensitivity | 1.07296120 |
| 49 | MP0005187_abnormal_penis_morphology | 1.07153460 |
| 50 | MP0008007_abnormal_cellular_replicative | 1.06331490 |
| 51 | MP0003136_yellow_coat_color | 1.05784744 |
| 52 | MP0000685_abnormal_immune_system | 1.03462224 |
| 53 | MP0005395_other_phenotype | 1.02650042 |
| 54 | MP0001919_abnormal_reproductive_system | 1.01434106 |
| 55 | MP0002938_white_spotting | 1.01306602 |
| 56 | MP0002277_abnormal_respiratory_mucosa | 0.99931936 |
| 57 | MP0003724_increased_susceptibility_to | 0.98299171 |
| 58 | MP0003252_abnormal_bile_duct | 0.93771727 |
| 59 | MP0005389_reproductive_system_phenotype | 0.93201896 |
| 60 | MP0002736_abnormal_nociception_after | 0.91989099 |
| 61 | MP0001293_anophthalmia | 0.90642374 |
| 62 | MP0009764_decreased_sensitivity_to | 0.89298141 |
| 63 | MP0005551_abnormal_eye_electrophysiolog | 0.85961896 |
| 64 | MP0003646_muscle_fatigue | 0.84153453 |
| 65 | MP0002160_abnormal_reproductive_system | 0.83518979 |
| 66 | MP0001845_abnormal_inflammatory_respons | 0.82670095 |
| 67 | MP0003868_abnormal_feces_composition | 0.82629513 |
| 68 | MP0001790_abnormal_immune_system | 0.81326983 |
| 69 | MP0005387_immune_system_phenotype | 0.81326983 |
| 70 | MP0008995_early_reproductive_senescence | 0.80568207 |
| 71 | MP0002723_abnormal_immune_serum | 0.79747434 |
| 72 | MP0004019_abnormal_vitamin_homeostasis | 0.77418598 |
| 73 | MP0005084_abnormal_gallbladder_morpholo | 0.77250486 |
| 74 | MP0003693_abnormal_embryo_hatching | 0.75566562 |
| 75 | MP0001764_abnormal_homeostasis | 0.73913063 |
| 76 | MP0009046_muscle_twitch | 0.72523380 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.71328792 |
| 78 | MP0008469_abnormal_protein_level | 0.70116376 |
| 79 | MP0001819_abnormal_immune_cell | 0.69894519 |
| 80 | MP0002420_abnormal_adaptive_immunity | 0.69636123 |
| 81 | MP0003878_abnormal_ear_physiology | 0.68424365 |
| 82 | MP0005377_hearing/vestibular/ear_phenot | 0.68424365 |
| 83 | MP0005025_abnormal_response_to | 0.68249700 |
| 84 | MP0001968_abnormal_touch/_nociception | 0.68008986 |
| 85 | MP0001501_abnormal_sleep_pattern | 0.67028898 |
| 86 | MP0008058_abnormal_DNA_repair | 0.65649404 |
| 87 | MP0001905_abnormal_dopamine_level | 0.65638735 |
| 88 | MP0005253_abnormal_eye_physiology | 0.65492913 |
| 89 | MP0009643_abnormal_urine_homeostasis | 0.65288557 |
| 90 | MP0010368_abnormal_lymphatic_system | 0.63742624 |
| 91 | MP0000647_abnormal_sebaceous_gland | 0.63643761 |
| 92 | MP0003315_abnormal_perineum_morphology | 0.61448649 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.61094189 |
| 94 | MP0000015_abnormal_ear_pigmentation | 0.59949336 |
| 95 | MP0001663_abnormal_digestive_system | 0.59683175 |
| 96 | MP0009745_abnormal_behavioral_response | 0.59126324 |
| 97 | MP0002132_abnormal_respiratory_system | 0.58971630 |
| 98 | MP0006035_abnormal_mitochondrial_morpho | 0.58486058 |
| 99 | MP0002398_abnormal_bone_marrow | 0.58094873 |
| 100 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.57911461 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.54786442 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.49785733 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.27549573 |
| 4 | Increased CSF lactate (HP:0002490) | 4.24112980 |
| 5 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.21435960 |
| 6 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.21435960 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.16382666 |
| 8 | Aplastic anemia (HP:0001915) | 4.16079854 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.12666025 |
| 10 | Renal Fanconi syndrome (HP:0001994) | 4.01552248 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.99742858 |
| 12 | Increased intramyocellular lipid droplets (HP:0012240) | 3.96558755 |
| 13 | Acute encephalopathy (HP:0006846) | 3.88179995 |
| 14 | Hepatic necrosis (HP:0002605) | 3.73876537 |
| 15 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.64496054 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.61216414 |
| 17 | Exertional dyspnea (HP:0002875) | 3.47383528 |
| 18 | Increased serum lactate (HP:0002151) | 3.38108250 |
| 19 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.27968348 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 3.20479331 |
| 21 | Increased muscle lipid content (HP:0009058) | 3.15913126 |
| 22 | Cerebral edema (HP:0002181) | 3.10610711 |
| 23 | Lactic acidosis (HP:0003128) | 3.03112047 |
| 24 | Hypoproteinemia (HP:0003075) | 2.94067296 |
| 25 | Multiple enchondromatosis (HP:0005701) | 2.87392329 |
| 26 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.80288040 |
| 27 | Generalized aminoaciduria (HP:0002909) | 2.77740174 |
| 28 | Glycosuria (HP:0003076) | 2.64204086 |
| 29 | Abnormality of urine glucose concentration (HP:0011016) | 2.64204086 |
| 30 | Progressive microcephaly (HP:0000253) | 2.63257654 |
| 31 | Respiratory difficulties (HP:0002880) | 2.58835555 |
| 32 | Optic neuritis (HP:0100653) | 2.49690875 |
| 33 | Retrobulbar optic neuritis (HP:0100654) | 2.49690875 |
| 34 | Type I transferrin isoform profile (HP:0003642) | 2.42629107 |
| 35 | Hyperphosphaturia (HP:0003109) | 2.40853004 |
| 36 | Abnormality of the pons (HP:0007361) | 2.40206209 |
| 37 | Abnormality of renal resorption (HP:0011038) | 2.37706910 |
| 38 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.36343775 |
| 39 | Exercise intolerance (HP:0003546) | 2.33145680 |
| 40 | Leukodystrophy (HP:0002415) | 2.32124264 |
| 41 | Lethargy (HP:0001254) | 2.29392906 |
| 42 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.24249518 |
| 43 | True hermaphroditism (HP:0010459) | 2.23461840 |
| 44 | Optic disc pallor (HP:0000543) | 2.23015014 |
| 45 | Abnormality of the prostate (HP:0008775) | 2.21188998 |
| 46 | Respiratory failure (HP:0002878) | 2.17099588 |
| 47 | Stenosis of the external auditory canal (HP:0000402) | 2.16306260 |
| 48 | Large for gestational age (HP:0001520) | 2.16274983 |
| 49 | Clubbing of toes (HP:0100760) | 2.15844851 |
| 50 | Flat capital femoral epiphysis (HP:0003370) | 2.07813987 |
| 51 | Colon cancer (HP:0003003) | 2.07429331 |
| 52 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.03955506 |
| 53 | Pancreatic fibrosis (HP:0100732) | 2.03393849 |
| 54 | Pancreatic cysts (HP:0001737) | 2.02422248 |
| 55 | Myositis (HP:0100614) | 1.98067298 |
| 56 | Hypoplasia of the pons (HP:0012110) | 1.97004706 |
| 57 | Orchitis (HP:0100796) | 1.97004284 |
| 58 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.96207613 |
| 59 | IgG deficiency (HP:0004315) | 1.96109513 |
| 60 | Type II lissencephaly (HP:0007260) | 1.94928523 |
| 61 | Oral leukoplakia (HP:0002745) | 1.94508894 |
| 62 | Meckel diverticulum (HP:0002245) | 1.93954707 |
| 63 | Abnormality of the preputium (HP:0100587) | 1.93448904 |
| 64 | Gangrene (HP:0100758) | 1.91677437 |
| 65 | CNS demyelination (HP:0007305) | 1.89505729 |
| 66 | Degeneration of anterior horn cells (HP:0002398) | 1.88656897 |
| 67 | Abnormality of the anterior horn cell (HP:0006802) | 1.88656897 |
| 68 | Methylmalonic acidemia (HP:0002912) | 1.87875618 |
| 69 | Cleft eyelid (HP:0000625) | 1.86708295 |
| 70 | Abnormality of the ileum (HP:0001549) | 1.85932942 |
| 71 | Metabolic acidosis (HP:0001942) | 1.85759259 |
| 72 | Molar tooth sign on MRI (HP:0002419) | 1.83579916 |
| 73 | Abnormality of midbrain morphology (HP:0002418) | 1.83579916 |
| 74 | X-linked dominant inheritance (HP:0001423) | 1.83212690 |
| 75 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.80210055 |
| 76 | Opisthotonus (HP:0002179) | 1.79949295 |
| 77 | Athetosis (HP:0002305) | 1.78307363 |
| 78 | Chromsome breakage (HP:0040012) | 1.78210098 |
| 79 | Hyperglycinemia (HP:0002154) | 1.77385961 |
| 80 | Panhypogammaglobulinemia (HP:0003139) | 1.76773332 |
| 81 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.76715808 |
| 82 | Abnormality of alanine metabolism (HP:0010916) | 1.76715808 |
| 83 | Hyperalaninemia (HP:0003348) | 1.76715808 |
| 84 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76204268 |
| 85 | Pancytopenia (HP:0001876) | 1.75442275 |
| 86 | Pendular nystagmus (HP:0012043) | 1.74694443 |
| 87 | Abnormality of serum amino acid levels (HP:0003112) | 1.74273771 |
| 88 | Limb dystonia (HP:0002451) | 1.72305085 |
| 89 | Forearm undergrowth (HP:0009821) | 1.71684996 |
| 90 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.71250428 |
| 91 | Spastic paraparesis (HP:0002313) | 1.71085443 |
| 92 | Hypoplasia of the ulna (HP:0003022) | 1.68259171 |
| 93 | Progressive inability to walk (HP:0002505) | 1.68166958 |
| 94 | Abnormal urine phosphate concentration (HP:0012599) | 1.67537219 |
| 95 | Keratoconjunctivitis sicca (HP:0001097) | 1.63541972 |
| 96 | Hypothermia (HP:0002045) | 1.61374652 |
| 97 | Sparse eyelashes (HP:0000653) | 1.61054705 |
| 98 | Cerebellar dysplasia (HP:0007033) | 1.59554093 |
| 99 | Keratoconjunctivitis (HP:0001096) | 1.58418958 |
| 100 | Hypoalbuminemia (HP:0003073) | 1.58307334 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 3.94619335 |
| 2 | VRK2 | 3.92937234 |
| 3 | MST4 | 3.81958282 |
| 4 | PBK | 3.43230129 |
| 5 | CDK19 | 3.26366547 |
| 6 | BUB1 | 3.18333812 |
| 7 | BMPR2 | 3.09971540 |
| 8 | EIF2AK1 | 2.97059022 |
| 9 | EIF2AK3 | 2.43707362 |
| 10 | TAOK3 | 2.41923890 |
| 11 | BCKDK | 2.37984188 |
| 12 | MUSK | 2.34397586 |
| 13 | MAP2K6 | 2.23553845 |
| 14 | TLK1 | 2.21359645 |
| 15 | OXSR1 | 2.19176951 |
| 16 | MAP3K12 | 2.14581805 |
| 17 | CDK8 | 1.84487506 |
| 18 | TSSK6 | 1.81208096 |
| 19 | VRK1 | 1.78892848 |
| 20 | TAF1 | 1.58016714 |
| 21 | MYLK | 1.55065400 |
| 22 | ZAK | 1.42473554 |
| 23 | PRKD3 | 1.41736716 |
| 24 | GRK1 | 1.36947518 |
| 25 | TXK | 1.34038257 |
| 26 | NEK1 | 1.32012800 |
| 27 | MAP4K2 | 1.25313077 |
| 28 | STK39 | 1.21748962 |
| 29 | DYRK2 | 1.19098065 |
| 30 | ADRBK2 | 1.17018976 |
| 31 | PLK3 | 1.13903699 |
| 32 | EPHA3 | 1.13484000 |
| 33 | WNK1 | 1.11727094 |
| 34 | KDR | 1.10295540 |
| 35 | NME1 | 1.08598652 |
| 36 | WNK4 | 1.08580213 |
| 37 | INSRR | 1.03982832 |
| 38 | NME2 | 1.01155032 |
| 39 | STK16 | 0.94191327 |
| 40 | EIF2AK2 | 0.88849640 |
| 41 | IKBKB | 0.76944255 |
| 42 | TNIK | 0.74135498 |
| 43 | DAPK1 | 0.73140276 |
| 44 | SRPK1 | 0.72547947 |
| 45 | PLK4 | 0.70731376 |
| 46 | PLK1 | 0.64533345 |
| 47 | ERBB3 | 0.64310442 |
| 48 | TIE1 | 0.63824115 |
| 49 | MAP3K14 | 0.63220723 |
| 50 | BMPR1B | 0.62059246 |
| 51 | PAK4 | 0.61565139 |
| 52 | WNK3 | 0.61391947 |
| 53 | CSNK1G2 | 0.60217283 |
| 54 | AURKB | 0.59749611 |
| 55 | CSNK1G3 | 0.59420440 |
| 56 | ABL2 | 0.57020296 |
| 57 | MARK3 | 0.55398440 |
| 58 | DAPK3 | 0.55155683 |
| 59 | PLK2 | 0.54893582 |
| 60 | CSNK2A2 | 0.54889291 |
| 61 | PAK1 | 0.53532811 |
| 62 | JAK3 | 0.52920774 |
| 63 | FLT3 | 0.52008025 |
| 64 | ATR | 0.51250857 |
| 65 | WEE1 | 0.50845696 |
| 66 | MAP3K4 | 0.50129340 |
| 67 | CSNK2A1 | 0.49363029 |
| 68 | CAMK2D | 0.48059659 |
| 69 | GRK5 | 0.47451583 |
| 70 | ADRBK1 | 0.45698372 |
| 71 | PRKCG | 0.45498069 |
| 72 | MAPKAPK5 | 0.42355406 |
| 73 | HIPK2 | 0.42004503 |
| 74 | CDK14 | 0.40544674 |
| 75 | PRKCQ | 0.40543640 |
| 76 | CSNK1G1 | 0.40004567 |
| 77 | KIT | 0.39707153 |
| 78 | LCK | 0.38974591 |
| 79 | AURKA | 0.38645554 |
| 80 | CDK11A | 0.38568357 |
| 81 | PRKCA | 0.38061001 |
| 82 | FES | 0.37589605 |
| 83 | CAMK2A | 0.36640185 |
| 84 | STK4 | 0.35854890 |
| 85 | ALK | 0.35391874 |
| 86 | CDC7 | 0.34837774 |
| 87 | ITK | 0.34678226 |
| 88 | PIK3CG | 0.34076958 |
| 89 | CSNK1A1L | 0.32741755 |
| 90 | MAPKAPK3 | 0.32076216 |
| 91 | STK11 | 0.31175607 |
| 92 | CAMKK2 | 0.30375443 |
| 93 | SIK3 | 0.30240088 |
| 94 | CDK15 | 0.29603938 |
| 95 | CDK18 | 0.28833589 |
| 96 | CSNK1A1 | 0.28294457 |
| 97 | CSF1R | 0.28248187 |
| 98 | OBSCN | 0.27587904 |
| 99 | LRRK2 | 0.27414114 |
| 100 | SMG1 | 0.27078541 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.29681256 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.11444693 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.28540598 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.28270961 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.08132512 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.88656818 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.75482764 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.73310004 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.72289926 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.46162315 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.34328431 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.19971724 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 2.19225191 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17089846 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.05440090 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.02528940 |
| 17 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.71123187 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.69495172 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.50240151 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.47056973 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38146463 |
| 22 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.36706049 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.32784294 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.32586096 |
| 25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.32421719 |
| 26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.31431346 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.25928188 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.19481886 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 1.19141396 |
| 30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.14947321 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.14578981 |
| 32 | Viral myocarditis_Homo sapiens_hsa05416 | 1.13577776 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11815025 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.07387080 |
| 35 | Mismatch repair_Homo sapiens_hsa03430 | 1.06645724 |
| 36 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.05506395 |
| 37 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.99350064 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99152107 |
| 39 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98462426 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.92084482 |
| 41 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.91345054 |
| 42 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.90321704 |
| 43 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.89060467 |
| 44 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.87104384 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85173361 |
| 46 | Leishmaniasis_Homo sapiens_hsa05140 | 0.84718584 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.84374908 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84186106 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.81065269 |
| 50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.80412856 |
| 51 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.80308749 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.79109509 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.78786567 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.77997514 |
| 55 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.77408240 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76848760 |
| 57 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.74793360 |
| 58 | RNA transport_Homo sapiens_hsa03013 | 0.73590063 |
| 59 | Carbon metabolism_Homo sapiens_hsa01200 | 0.72097632 |
| 60 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.68534640 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.68152806 |
| 62 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.67256923 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67150955 |
| 64 | Base excision repair_Homo sapiens_hsa03410 | 0.66520676 |
| 65 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.66052685 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.65471383 |
| 67 | Basal transcription factors_Homo sapiens_hsa03022 | 0.65351113 |
| 68 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.64252575 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63701588 |
| 70 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.62954073 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62014590 |
| 72 | Purine metabolism_Homo sapiens_hsa00230 | 0.59731390 |
| 73 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.59688026 |
| 74 | Spliceosome_Homo sapiens_hsa03040 | 0.56204971 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.55602045 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54961425 |
| 77 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.51989177 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51213722 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51044722 |
| 80 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.50292924 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49508930 |
| 82 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49003961 |
| 83 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46747451 |
| 84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.46441412 |
| 85 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43744135 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.43675230 |
| 87 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39339938 |
| 88 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.38472247 |
| 89 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.37825732 |
| 90 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37668864 |
| 91 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.37468265 |
| 92 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.34131747 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.33549663 |
| 94 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33371903 |
| 95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33226770 |
| 96 | Phototransduction_Homo sapiens_hsa04744 | 0.32977436 |
| 97 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.32011867 |
| 98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.31505215 |
| 99 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.31365479 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31303430 |

