

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cell wall macromolecule catabolic process (GO:0016998) | 8.15484592 |
| 2 | cell wall macromolecule metabolic process (GO:0044036) | 6.76094691 |
| 3 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 6.28419629 |
| 4 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 5.60839671 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.50598126 |
| 6 | DNA deamination (GO:0045006) | 5.28401117 |
| 7 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 5.22891166 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.09661834 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 5.09661834 |
| 10 | neurofilament cytoskeleton organization (GO:0060052) | 4.76301355 |
| 11 | neurotransmitter catabolic process (GO:0042135) | 4.44506943 |
| 12 | protein complex biogenesis (GO:0070271) | 4.18502051 |
| 13 | retinal cone cell development (GO:0046549) | 4.17417680 |
| 14 | cytidine metabolic process (GO:0046087) | 4.16786254 |
| 15 | cytidine catabolic process (GO:0006216) | 4.16786254 |
| 16 | cytidine deamination (GO:0009972) | 4.16786254 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.13690900 |
| 18 | cullin deneddylation (GO:0010388) | 4.09912669 |
| 19 | DNA strand renaturation (GO:0000733) | 4.07907411 |
| 20 | behavioral response to nicotine (GO:0035095) | 4.07352270 |
| 21 | anterograde axon cargo transport (GO:0008089) | 4.03064413 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.02990934 |
| 23 | synaptic transmission, cholinergic (GO:0007271) | 4.00749925 |
| 24 | positive regulation of amino acid transport (GO:0051957) | 3.97952537 |
| 25 | chaperone-mediated protein transport (GO:0072321) | 3.92397568 |
| 26 | somite development (GO:0061053) | 3.89685624 |
| 27 | protein localization to kinetochore (GO:0034501) | 3.83410182 |
| 28 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.81761352 |
| 29 | protein deneddylation (GO:0000338) | 3.81620434 |
| 30 | retinal ganglion cell axon guidance (GO:0031290) | 3.78854120 |
| 31 | interferon-gamma production (GO:0032609) | 3.74911929 |
| 32 | signal peptide processing (GO:0006465) | 3.72200090 |
| 33 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.67206104 |
| 34 | termination of RNA polymerase III transcription (GO:0006386) | 3.67206104 |
| 35 | adaptation of signaling pathway (GO:0023058) | 3.66728118 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.65738705 |
| 37 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.65738705 |
| 38 | NADH dehydrogenase complex assembly (GO:0010257) | 3.65738705 |
| 39 | replication fork processing (GO:0031297) | 3.62532678 |
| 40 | proteasome assembly (GO:0043248) | 3.54340953 |
| 41 | intermediate filament organization (GO:0045109) | 3.53593202 |
| 42 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.47541346 |
| 43 | respiratory electron transport chain (GO:0022904) | 3.41250354 |
| 44 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 3.40966106 |
| 45 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.39021279 |
| 46 | T cell lineage commitment (GO:0002360) | 3.37655271 |
| 47 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.37188579 |
| 48 | regulation of chronic inflammatory response (GO:0002676) | 3.34599429 |
| 49 | platelet dense granule organization (GO:0060155) | 3.33549856 |
| 50 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.33034273 |
| 51 | electron transport chain (GO:0022900) | 3.31795329 |
| 52 | negative regulation of DNA recombination (GO:0045910) | 3.18007196 |
| 53 | lipopolysaccharide metabolic process (GO:0008653) | 3.17706961 |
| 54 | alkaloid metabolic process (GO:0009820) | 3.04529866 |
| 55 | hydrogen ion transmembrane transport (GO:1902600) | 3.03628246 |
| 56 | regulation of mesoderm development (GO:2000380) | 3.02061061 |
| 57 | anterograde synaptic vesicle transport (GO:0048490) | 3.01514308 |
| 58 | lymphoid progenitor cell differentiation (GO:0002320) | 3.01342820 |
| 59 | GPI anchor biosynthetic process (GO:0006506) | 2.95271966 |
| 60 | histone H2A monoubiquitination (GO:0035518) | 2.94512973 |
| 61 | gamma-aminobutyric acid transport (GO:0015812) | 2.93909860 |
| 62 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.91146727 |
| 63 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.91146727 |
| 64 | isotype switching (GO:0045190) | 2.91146727 |
| 65 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.90353656 |
| 66 | negative regulation of multicellular organism growth (GO:0040015) | 2.89313657 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.86980477 |
| 68 | GPI anchor metabolic process (GO:0006505) | 2.85888348 |
| 69 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.83264600 |
| 70 | ATP biosynthetic process (GO:0006754) | 2.80073515 |
| 71 | oxidative phosphorylation (GO:0006119) | 2.78117685 |
| 72 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.74453389 |
| 73 | proton transport (GO:0015992) | 2.73616859 |
| 74 | postsynaptic membrane organization (GO:0001941) | 2.69561972 |
| 75 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.69268357 |
| 76 | positive regulation of organic acid transport (GO:0032892) | 2.67038433 |
| 77 | hydrogen transport (GO:0006818) | 2.64703829 |
| 78 | indole-containing compound catabolic process (GO:0042436) | 2.64618923 |
| 79 | indolalkylamine catabolic process (GO:0046218) | 2.64618923 |
| 80 | tryptophan catabolic process (GO:0006569) | 2.64618923 |
| 81 | myoblast migration (GO:0051451) | 2.62136314 |
| 82 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.60713997 |
| 83 | cellular biogenic amine catabolic process (GO:0042402) | 2.60357775 |
| 84 | amine catabolic process (GO:0009310) | 2.60357775 |
| 85 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.58951627 |
| 86 | spliceosomal complex assembly (GO:0000245) | 2.58565693 |
| 87 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.58182319 |
| 88 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.57499620 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.57474450 |
| 90 | maturation of SSU-rRNA (GO:0030490) | 2.57043675 |
| 91 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.54599135 |
| 92 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.53577850 |
| 93 | protein heterotetramerization (GO:0051290) | 2.51633531 |
| 94 | lysine catabolic process (GO:0006554) | 2.50813650 |
| 95 | lysine metabolic process (GO:0006553) | 2.50813650 |
| 96 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.49491309 |
| 97 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.49491309 |
| 98 | ubiquinone metabolic process (GO:0006743) | 2.49081891 |
| 99 | neurotransmitter metabolic process (GO:0042133) | 2.46369897 |
| 100 | negative regulation of B cell apoptotic process (GO:0002903) | 2.46003386 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.54122264 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.72243546 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.22455005 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.05247810 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.56040021 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.38463735 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.26416823 |
| 8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.77623869 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.43101793 |
| 10 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.42325547 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.37700281 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.22693029 |
| 13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.19724183 |
| 14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.16791028 |
| 15 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.08023132 |
| 16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.04143770 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.00252180 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97824646 |
| 19 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.97111240 |
| 20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.91281072 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.88073513 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.84885740 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.81413370 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.81101388 |
| 25 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.78746642 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74849673 |
| 27 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.74362296 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72729316 |
| 29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.70130686 |
| 30 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.64900315 |
| 31 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.62969203 |
| 32 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.62962000 |
| 33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.62530091 |
| 34 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.61996024 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58756837 |
| 36 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.57236243 |
| 37 | FUS_26573619_Chip-Seq_HEK293_Human | 1.50420999 |
| 38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.49439828 |
| 39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.49170257 |
| 40 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.49025034 |
| 41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48171276 |
| 42 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.47899418 |
| 43 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.45963841 |
| 44 | EWS_26573619_Chip-Seq_HEK293_Human | 1.45708617 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44657823 |
| 46 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.44499124 |
| 47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40241117 |
| 48 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.38872659 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.37960142 |
| 50 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.32732183 |
| 51 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.31637046 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27982607 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.19516860 |
| 54 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17849059 |
| 55 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.17551920 |
| 56 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.17163612 |
| 57 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.16591251 |
| 58 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13530196 |
| 59 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.13471708 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.08727709 |
| 61 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.08518337 |
| 62 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.07066838 |
| 63 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06715957 |
| 64 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05990381 |
| 65 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.05888366 |
| 66 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05738471 |
| 67 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03928113 |
| 68 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.03214628 |
| 69 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.03018989 |
| 70 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.01957747 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01636063 |
| 72 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01448537 |
| 73 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.00227137 |
| 74 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00177672 |
| 75 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.99844366 |
| 76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99512889 |
| 77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99512889 |
| 78 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98468487 |
| 79 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.98391683 |
| 80 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98291391 |
| 81 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96821901 |
| 82 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.96472268 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 0.96130296 |
| 84 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.95362982 |
| 85 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.95229730 |
| 86 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.95229730 |
| 87 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.94461824 |
| 88 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.94005524 |
| 89 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92426473 |
| 90 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92426473 |
| 91 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.92162212 |
| 92 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.92134848 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91426910 |
| 94 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.89883053 |
| 95 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88417667 |
| 96 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.88145809 |
| 97 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.86295815 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.86272779 |
| 99 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.85395551 |
| 100 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.83382660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002638_abnormal_pupillary_reflex | 7.15590662 |
| 2 | MP0002234_abnormal_pharynx_morphology | 4.02921361 |
| 3 | MP0010386_abnormal_urinary_bladder | 3.41014473 |
| 4 | MP0002735_abnormal_chemical_nociception | 3.24581241 |
| 5 | MP0001853_heart_inflammation | 2.61345089 |
| 6 | MP0006082_CNS_inflammation | 2.44389069 |
| 7 | MP0009053_abnormal_anal_canal | 2.41360660 |
| 8 | MP0003136_yellow_coat_color | 2.34933496 |
| 9 | MP0002102_abnormal_ear_morphology | 2.32217946 |
| 10 | MP0004147_increased_porphyrin_level | 2.31277559 |
| 11 | MP0005671_abnormal_response_to | 2.27716859 |
| 12 | MP0003283_abnormal_digestive_organ | 2.21525206 |
| 13 | MP0005551_abnormal_eye_electrophysiolog | 2.13466197 |
| 14 | MP0003011_delayed_dark_adaptation | 2.04617023 |
| 15 | MP0001873_stomach_inflammation | 1.95658957 |
| 16 | MP0000579_abnormal_nail_morphology | 1.94599938 |
| 17 | MP0001502_abnormal_circadian_rhythm | 1.87553314 |
| 18 | MP0002272_abnormal_nervous_system | 1.86423771 |
| 19 | MP0008058_abnormal_DNA_repair | 1.85278604 |
| 20 | MP0002736_abnormal_nociception_after | 1.80044477 |
| 21 | MP0005075_abnormal_melanosome_morpholog | 1.78786649 |
| 22 | MP0004381_abnormal_hair_follicle | 1.78527901 |
| 23 | MP0003119_abnormal_digestive_system | 1.78261614 |
| 24 | MP0001984_abnormal_olfaction | 1.76795244 |
| 25 | MP0000383_abnormal_hair_follicle | 1.74624299 |
| 26 | MP0003786_premature_aging | 1.73990689 |
| 27 | MP0001348_abnormal_lacrimal_gland | 1.72259657 |
| 28 | MP0008789_abnormal_olfactory_epithelium | 1.71026491 |
| 29 | MP0004510_myositis | 1.69254099 |
| 30 | MP0000538_abnormal_urinary_bladder | 1.60515283 |
| 31 | MP0001293_anophthalmia | 1.60128646 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.57479633 |
| 33 | MP0004142_abnormal_muscle_tone | 1.57199420 |
| 34 | MP0001970_abnormal_pain_threshold | 1.51071676 |
| 35 | MP0000013_abnormal_adipose_tissue | 1.50842284 |
| 36 | MP0005423_abnormal_somatic_nervous | 1.43392758 |
| 37 | MP0002163_abnormal_gland_morphology | 1.38934465 |
| 38 | MP0005253_abnormal_eye_physiology | 1.36872469 |
| 39 | MP0009745_abnormal_behavioral_response | 1.35985144 |
| 40 | MP0003718_maternal_effect | 1.35495119 |
| 41 | MP0009765_abnormal_xenobiotic_induced | 1.29117834 |
| 42 | MP0005197_abnormal_uvea_morphology | 1.28951966 |
| 43 | MP0001968_abnormal_touch/_nociception | 1.25881706 |
| 44 | MP0003880_abnormal_central_pattern | 1.25614040 |
| 45 | MP0008872_abnormal_physiological_respon | 1.19808683 |
| 46 | MP0000372_irregular_coat_pigmentation | 1.19392506 |
| 47 | MP0005394_taste/olfaction_phenotype | 1.18909514 |
| 48 | MP0005499_abnormal_olfactory_system | 1.18909514 |
| 49 | MP0002095_abnormal_skin_pigmentation | 1.08692646 |
| 50 | MP0002138_abnormal_hepatobiliary_system | 1.08343101 |
| 51 | MP0003567_abnormal_fetal_cardiomyocyte | 1.07378287 |
| 52 | MP0005310_abnormal_salivary_gland | 1.06831626 |
| 53 | MP0002090_abnormal_vision | 1.06250092 |
| 54 | MP0002733_abnormal_thermal_nociception | 1.04977508 |
| 55 | MP0010094_abnormal_chromosome_stability | 1.04383813 |
| 56 | MP0002751_abnormal_autonomic_nervous | 1.04224823 |
| 57 | MP0001986_abnormal_taste_sensitivity | 1.03480829 |
| 58 | MP0001835_abnormal_antigen_presentation | 1.01596152 |
| 59 | MP0006036_abnormal_mitochondrial_physio | 1.00591878 |
| 60 | MP0003942_abnormal_urinary_system | 1.00264525 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 0.99848244 |
| 62 | MP0000647_abnormal_sebaceous_gland | 0.99561922 |
| 63 | MP0006292_abnormal_olfactory_placode | 0.96717246 |
| 64 | MP0003385_abnormal_body_wall | 0.95563319 |
| 65 | MP0008873_increased_physiological_sensi | 0.94900821 |
| 66 | MP0003635_abnormal_synaptic_transmissio | 0.93053542 |
| 67 | MP0002233_abnormal_nose_morphology | 0.92706344 |
| 68 | MP0005084_abnormal_gallbladder_morpholo | 0.89497604 |
| 69 | MP0001756_abnormal_urination | 0.89462948 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.88557778 |
| 71 | MP0001661_extended_life_span | 0.86795317 |
| 72 | MP0000685_abnormal_immune_system | 0.84327510 |
| 73 | MP0005195_abnormal_posterior_eye | 0.83218250 |
| 74 | MP0005645_abnormal_hypothalamus_physiol | 0.80800950 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.79659723 |
| 76 | MP0001324_abnormal_eye_pigmentation | 0.79431749 |
| 77 | MP0001800_abnormal_humoral_immune | 0.76631830 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.75108326 |
| 79 | MP0002064_seizures | 0.73543560 |
| 80 | MP0010678_abnormal_skin_adnexa | 0.73255498 |
| 81 | MP0001905_abnormal_dopamine_level | 0.71428672 |
| 82 | MP0000537_abnormal_urethra_morphology | 0.69418499 |
| 83 | MP0005391_vision/eye_phenotype | 0.68047110 |
| 84 | MP0008775_abnormal_heart_ventricle | 0.67158666 |
| 85 | MP0004859_abnormal_synaptic_plasticity | 0.66881524 |
| 86 | MP0002734_abnormal_mechanical_nocicepti | 0.65804876 |
| 87 | MP0004019_abnormal_vitamin_homeostasis | 0.65415758 |
| 88 | MP0002693_abnormal_pancreas_physiology | 0.64555473 |
| 89 | MP0008995_early_reproductive_senescence | 0.62548647 |
| 90 | MP0003787_abnormal_imprinting | 0.62407814 |
| 91 | MP0002177_abnormal_outer_ear | 0.60879201 |
| 92 | MP0003195_calcinosis | 0.60208653 |
| 93 | MP0009250_abnormal_appendicular_skeleto | 0.60031771 |
| 94 | MP0001764_abnormal_homeostasis | 0.60016655 |
| 95 | MP0000534_abnormal_ureter_morphology | 0.59987046 |
| 96 | MP0004134_abnormal_chest_morphology | 0.59927216 |
| 97 | MP0005000_abnormal_immune_tolerance | 0.59892111 |
| 98 | MP0005379_endocrine/exocrine_gland_phen | 0.59892023 |
| 99 | MP0000230_abnormal_systemic_arterial | 0.59128749 |
| 100 | MP0005174_abnormal_tail_pigmentation | 0.59089623 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ulnar claw (HP:0001178) | 4.97010818 |
| 2 | Gait imbalance (HP:0002141) | 4.33661260 |
| 3 | Congenital primary aphakia (HP:0007707) | 4.10658166 |
| 4 | Medial flaring of the eyebrow (HP:0010747) | 4.04852442 |
| 5 | Nephrogenic diabetes insipidus (HP:0009806) | 3.88993241 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.65490630 |
| 7 | Absent phalangeal crease (HP:0006109) | 3.47772354 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.46123093 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 3.39450982 |
| 10 | Vaginal atresia (HP:0000148) | 3.26032154 |
| 11 | Acute encephalopathy (HP:0006846) | 3.25579866 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.15429001 |
| 13 | Genital tract atresia (HP:0001827) | 3.10472825 |
| 14 | Abnormal finger flexion creases (HP:0006143) | 3.04759595 |
| 15 | Increased CSF lactate (HP:0002490) | 2.98449471 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97633020 |
| 17 | IgG deficiency (HP:0004315) | 2.94664590 |
| 18 | Broad foot (HP:0001769) | 2.87541742 |
| 19 | Progressive macrocephaly (HP:0004481) | 2.84523537 |
| 20 | Abnormality of midbrain morphology (HP:0002418) | 2.80785204 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.80785204 |
| 22 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.78799218 |
| 23 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.78479756 |
| 24 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.72316653 |
| 25 | Abnormal number of incisors (HP:0011064) | 2.67304067 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67037181 |
| 27 | Concave nail (HP:0001598) | 2.64663949 |
| 28 | Abnormality of the renal collecting system (HP:0004742) | 2.63131692 |
| 29 | Parakeratosis (HP:0001036) | 2.61205272 |
| 30 | Congenital stationary night blindness (HP:0007642) | 2.58993312 |
| 31 | Lipid accumulation in hepatocytes (HP:0006561) | 2.57379977 |
| 32 | Brittle hair (HP:0002299) | 2.55209772 |
| 33 | Follicular hyperkeratosis (HP:0007502) | 2.54573941 |
| 34 | Pendular nystagmus (HP:0012043) | 2.54279094 |
| 35 | Atonic seizures (HP:0010819) | 2.51586725 |
| 36 | Methylmalonic aciduria (HP:0012120) | 2.50630089 |
| 37 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.49279055 |
| 38 | Poor coordination (HP:0002370) | 2.49152361 |
| 39 | Large for gestational age (HP:0001520) | 2.47570619 |
| 40 | Hyperglycinemia (HP:0002154) | 2.46353223 |
| 41 | Pancreatic cysts (HP:0001737) | 2.44864976 |
| 42 | Duplicated collecting system (HP:0000081) | 2.44645919 |
| 43 | Neuroendocrine neoplasm (HP:0100634) | 2.44439787 |
| 44 | Pili torti (HP:0003777) | 2.43906305 |
| 45 | Increased intramyocellular lipid droplets (HP:0012240) | 2.41726901 |
| 46 | CNS hypomyelination (HP:0003429) | 2.40496443 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.37312518 |
| 48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.37312518 |
| 49 | Status epilepticus (HP:0002133) | 2.36834978 |
| 50 | Bilateral microphthalmos (HP:0007633) | 2.31841787 |
| 51 | Conjunctival telangiectasia (HP:0000524) | 2.30877977 |
| 52 | Cerebral edema (HP:0002181) | 2.29915540 |
| 53 | Optic disc pallor (HP:0000543) | 2.26202119 |
| 54 | Abnormality of renal resorption (HP:0011038) | 2.24007487 |
| 55 | Diplopia (HP:0000651) | 2.22199495 |
| 56 | Abnormality of binocular vision (HP:0011514) | 2.22199495 |
| 57 | Renal Fanconi syndrome (HP:0001994) | 2.19460287 |
| 58 | Abnormal hair laboratory examination (HP:0003328) | 2.16859637 |
| 59 | Lethargy (HP:0001254) | 2.13465639 |
| 60 | Short 5th finger (HP:0009237) | 2.13271943 |
| 61 | Hepatocellular necrosis (HP:0001404) | 2.10035657 |
| 62 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.09948942 |
| 63 | Hypoplasia of the fovea (HP:0007750) | 2.09948942 |
| 64 | Increased serum lactate (HP:0002151) | 2.07122609 |
| 65 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.04247523 |
| 66 | Cerebral hypomyelination (HP:0006808) | 1.99320678 |
| 67 | Pheochromocytoma (HP:0002666) | 1.99305236 |
| 68 | Humeroradial synostosis (HP:0003041) | 1.99295715 |
| 69 | Synostosis involving the elbow (HP:0003938) | 1.99295715 |
| 70 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.97466717 |
| 71 | Maternal diabetes (HP:0009800) | 1.93256396 |
| 72 | Left ventricular hypertrophy (HP:0001712) | 1.91449234 |
| 73 | Hepatic necrosis (HP:0002605) | 1.90965978 |
| 74 | Methylmalonic acidemia (HP:0002912) | 1.90661398 |
| 75 | Increased muscle lipid content (HP:0009058) | 1.89231664 |
| 76 | Septo-optic dysplasia (HP:0100842) | 1.89040507 |
| 77 | Lactic acidosis (HP:0003128) | 1.88204128 |
| 78 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.86724625 |
| 79 | Exercise intolerance (HP:0003546) | 1.85825457 |
| 80 | Blindness (HP:0000618) | 1.85428826 |
| 81 | Nephrotic syndrome (HP:0000100) | 1.84832846 |
| 82 | Type I transferrin isoform profile (HP:0003642) | 1.83793105 |
| 83 | Sparse eyelashes (HP:0000653) | 1.80483139 |
| 84 | Leukodystrophy (HP:0002415) | 1.79169185 |
| 85 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.79039287 |
| 86 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78724070 |
| 87 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.78367591 |
| 88 | Severe combined immunodeficiency (HP:0004430) | 1.77667303 |
| 89 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.77124043 |
| 90 | Dental crowding (HP:0000678) | 1.75693311 |
| 91 | Pancreatic fibrosis (HP:0100732) | 1.75375342 |
| 92 | Coronal craniosynostosis (HP:0004440) | 1.74999061 |
| 93 | Exertional dyspnea (HP:0002875) | 1.73918248 |
| 94 | Chronic hepatic failure (HP:0100626) | 1.73208542 |
| 95 | Specific learning disability (HP:0001328) | 1.73201610 |
| 96 | True hermaphroditism (HP:0010459) | 1.70849614 |
| 97 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.68642377 |
| 98 | Hyperglycinuria (HP:0003108) | 1.67784549 |
| 99 | Reduced antithrombin III activity (HP:0001976) | 1.67007959 |
| 100 | Nephronophthisis (HP:0000090) | 1.66901421 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.17756872 |
| 2 | GRK7 | 3.76917964 |
| 3 | BMPR1B | 3.57538780 |
| 4 | ACVR1B | 3.29022947 |
| 5 | MOS | 2.93849373 |
| 6 | TIE1 | 2.64592840 |
| 7 | EIF2AK1 | 2.54723187 |
| 8 | PDK2 | 2.53259703 |
| 9 | TGFBR2 | 2.51564784 |
| 10 | MST4 | 2.31458324 |
| 11 | NME1 | 2.25477522 |
| 12 | VRK2 | 2.14812165 |
| 13 | PBK | 1.93809610 |
| 14 | GRK5 | 1.78404032 |
| 15 | VRK1 | 1.74739809 |
| 16 | MKNK2 | 1.73431049 |
| 17 | STK10 | 1.68791432 |
| 18 | EIF2AK2 | 1.64141349 |
| 19 | MARK1 | 1.55439736 |
| 20 | NUAK1 | 1.44418738 |
| 21 | MAP4K2 | 1.43863217 |
| 22 | GRK1 | 1.33754351 |
| 23 | BCKDK | 1.29661981 |
| 24 | SIK2 | 1.25008779 |
| 25 | NEK1 | 1.19960223 |
| 26 | MAPK13 | 1.19291990 |
| 27 | BCR | 1.18256029 |
| 28 | ADRBK2 | 1.17297743 |
| 29 | ADRBK1 | 1.16823000 |
| 30 | BUB1 | 1.15594205 |
| 31 | MKNK1 | 1.14733686 |
| 32 | DAPK1 | 1.04502162 |
| 33 | ITK | 1.03567137 |
| 34 | TGFBR1 | 1.02294518 |
| 35 | SRPK1 | 1.00715540 |
| 36 | DYRK2 | 0.94277434 |
| 37 | NTRK2 | 0.89522043 |
| 38 | AURKA | 0.84033589 |
| 39 | TLK1 | 0.83008949 |
| 40 | ARAF | 0.82037125 |
| 41 | MAP3K9 | 0.80408132 |
| 42 | WNK3 | 0.79771457 |
| 43 | NEK2 | 0.78565142 |
| 44 | CCNB1 | 0.77233605 |
| 45 | KDR | 0.74435182 |
| 46 | PRKCG | 0.72768644 |
| 47 | MAP3K4 | 0.72169697 |
| 48 | STK38L | 0.70973234 |
| 49 | PRKCE | 0.67631248 |
| 50 | PLK4 | 0.67544434 |
| 51 | ERBB4 | 0.67356094 |
| 52 | PIK3CA | 0.65680491 |
| 53 | ILK | 0.63017072 |
| 54 | IGF1R | 0.60211648 |
| 55 | PLK3 | 0.59668232 |
| 56 | EPHA4 | 0.59243316 |
| 57 | CSF1R | 0.57337350 |
| 58 | ERBB2 | 0.56027452 |
| 59 | PRKACB | 0.55901444 |
| 60 | CAMK2A | 0.55876900 |
| 61 | PIM2 | 0.55512462 |
| 62 | INSRR | 0.54617618 |
| 63 | TAF1 | 0.48849887 |
| 64 | DYRK1A | 0.45870098 |
| 65 | DYRK3 | 0.45515606 |
| 66 | TNIK | 0.44545437 |
| 67 | STK24 | 0.43465565 |
| 68 | IKBKB | 0.43251791 |
| 69 | PHKG2 | 0.42437123 |
| 70 | PHKG1 | 0.42437123 |
| 71 | CDK5 | 0.40968372 |
| 72 | FGFR1 | 0.40855070 |
| 73 | FRK | 0.39624508 |
| 74 | PRKCI | 0.39105472 |
| 75 | TAOK3 | 0.38561406 |
| 76 | CDK3 | 0.38026594 |
| 77 | MAPKAPK5 | 0.37669882 |
| 78 | PRKACA | 0.36559658 |
| 79 | RPS6KA4 | 0.36399977 |
| 80 | MAPK12 | 0.35847692 |
| 81 | RPS6KA5 | 0.35653144 |
| 82 | PIK3CG | 0.35115406 |
| 83 | INSR | 0.34897483 |
| 84 | TSSK6 | 0.34723026 |
| 85 | CSNK1G3 | 0.34400049 |
| 86 | PDK1 | 0.33678465 |
| 87 | ATM | 0.33218717 |
| 88 | PRKCH | 0.32746162 |
| 89 | EIF2AK3 | 0.32087729 |
| 90 | CDC7 | 0.31837209 |
| 91 | PRKCQ | 0.30932822 |
| 92 | WEE1 | 0.29417922 |
| 93 | TEC | 0.29378410 |
| 94 | CSNK2A2 | 0.29315147 |
| 95 | LYN | 0.27833633 |
| 96 | PAK3 | 0.27764685 |
| 97 | ZAK | 0.27190620 |
| 98 | PRKACG | 0.26883571 |
| 99 | CSNK2A1 | 0.26612088 |
| 100 | PRKDC | 0.26337041 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.67116324 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.46124604 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.16176910 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.06377392 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.46418759 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.39466588 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.26312440 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25440295 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.17748382 |
| 10 | Nicotine addiction_Homo sapiens_hsa05033 | 2.15097126 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 2.08553708 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.07198591 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 2.05288981 |
| 14 | Protein export_Homo sapiens_hsa03060 | 2.04708219 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.95043527 |
| 16 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.94012234 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.93648757 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.91280713 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.90890425 |
| 20 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.87031170 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.80508447 |
| 22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.74498079 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.67433349 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.59061190 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.56568568 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.52436080 |
| 27 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.49348096 |
| 28 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.48007501 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 1.41635002 |
| 30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.40302121 |
| 31 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.39693224 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.37282614 |
| 33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.34204903 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.32213339 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27988577 |
| 36 | RNA degradation_Homo sapiens_hsa03018 | 1.27295450 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.22039686 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.19211072 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.11144790 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06440528 |
| 41 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.04771482 |
| 42 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.01178473 |
| 43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.00753219 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.97812314 |
| 45 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.97806662 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.94457952 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.94037011 |
| 48 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.93984980 |
| 49 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.93109977 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.92844089 |
| 51 | GABAergic synapse_Homo sapiens_hsa04727 | 0.90451134 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.89188625 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85770531 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.83903684 |
| 55 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.79410430 |
| 56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.78122554 |
| 57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.77520507 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.76270298 |
| 59 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.73511164 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.73157039 |
| 61 | Spliceosome_Homo sapiens_hsa03040 | 0.72602786 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72036786 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70376781 |
| 64 | Morphine addiction_Homo sapiens_hsa05032 | 0.69958695 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69375083 |
| 66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.67817531 |
| 67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.65160300 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.65151707 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.63597636 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.63275618 |
| 71 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.62105783 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58504861 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58371153 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57134752 |
| 75 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.49155587 |
| 76 | ABC transporters_Homo sapiens_hsa02010 | 0.48362624 |
| 77 | RNA transport_Homo sapiens_hsa03013 | 0.47244754 |
| 78 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.47147999 |
| 79 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47115867 |
| 80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47096450 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.46971570 |
| 82 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.44027311 |
| 83 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.43579451 |
| 84 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.42040554 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.41880077 |
| 86 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.37115492 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.36812705 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.36708261 |
| 89 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36401471 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36049861 |
| 91 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.35656578 |
| 92 | Base excision repair_Homo sapiens_hsa03410 | 0.34740465 |
| 93 | Circadian rhythm_Homo sapiens_hsa04710 | 0.34002379 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.33623394 |
| 95 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.33242055 |
| 96 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32915364 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.31443006 |
| 98 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.30084542 |
| 99 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.28637663 |
| 100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28220779 |

