

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.96365808 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.81676951 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.81676951 |
| 4 | sequestering of actin monomers (GO:0042989) | 5.27176701 |
| 5 | respiratory electron transport chain (GO:0022904) | 4.60840229 |
| 6 | electron transport chain (GO:0022900) | 4.53201667 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 4.52503351 |
| 8 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.50739048 |
| 9 | viral transcription (GO:0019083) | 4.02090836 |
| 10 | tryptophan catabolic process (GO:0006569) | 4.00426105 |
| 11 | indole-containing compound catabolic process (GO:0042436) | 4.00426105 |
| 12 | indolalkylamine catabolic process (GO:0046218) | 4.00426105 |
| 13 | kynurenine metabolic process (GO:0070189) | 3.98496585 |
| 14 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.97968398 |
| 15 | termination of RNA polymerase III transcription (GO:0006386) | 3.97968398 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.92356591 |
| 17 | maturation of SSU-rRNA (GO:0030490) | 3.82487794 |
| 18 | base-excision repair, AP site formation (GO:0006285) | 3.79391735 |
| 19 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.78901963 |
| 20 | protein complex biogenesis (GO:0070271) | 3.78365077 |
| 21 | ribosomal large subunit biogenesis (GO:0042273) | 3.77723519 |
| 22 | translational termination (GO:0006415) | 3.73537505 |
| 23 | hydrogen ion transmembrane transport (GO:1902600) | 3.69584936 |
| 24 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.64740803 |
| 25 | NADH dehydrogenase complex assembly (GO:0010257) | 3.64740803 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.64740803 |
| 27 | ATP biosynthetic process (GO:0006754) | 3.64503846 |
| 28 | spinal cord association neuron differentiation (GO:0021527) | 3.61952568 |
| 29 | translational elongation (GO:0006414) | 3.61861346 |
| 30 | negative regulation of mast cell activation (GO:0033004) | 3.59198876 |
| 31 | respiratory chain complex IV assembly (GO:0008535) | 3.59037107 |
| 32 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.57073804 |
| 33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.56425556 |
| 34 | cotranslational protein targeting to membrane (GO:0006613) | 3.50626763 |
| 35 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.48747629 |
| 36 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.48708309 |
| 37 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.48708309 |
| 38 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.47525856 |
| 39 | platelet dense granule organization (GO:0060155) | 3.47215703 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46419465 |
| 41 | protein targeting to ER (GO:0045047) | 3.40344678 |
| 42 | opioid receptor signaling pathway (GO:0038003) | 3.39631880 |
| 43 | proton transport (GO:0015992) | 3.38009332 |
| 44 | tryptophan metabolic process (GO:0006568) | 3.37577191 |
| 45 | chaperone-mediated protein transport (GO:0072321) | 3.33588790 |
| 46 | tachykinin receptor signaling pathway (GO:0007217) | 3.33022812 |
| 47 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.29327555 |
| 48 | hydrogen transport (GO:0006818) | 3.28909382 |
| 49 | positive regulation of protein homodimerization activity (GO:0090073) | 3.28311560 |
| 50 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.26897658 |
| 51 | histone H2A acetylation (GO:0043968) | 3.26671914 |
| 52 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.26554386 |
| 53 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.26533273 |
| 54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.26478638 |
| 55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.26478638 |
| 56 | protein localization to endoplasmic reticulum (GO:0070972) | 3.25979792 |
| 57 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.21154177 |
| 58 | negative regulation of ligase activity (GO:0051352) | 3.21154177 |
| 59 | inner mitochondrial membrane organization (GO:0007007) | 3.19341260 |
| 60 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.17530257 |
| 61 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.17522603 |
| 62 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.16742574 |
| 63 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.15663155 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.14863397 |
| 65 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.14863397 |
| 66 | regulation of cellular respiration (GO:0043457) | 3.12998735 |
| 67 | behavioral response to nicotine (GO:0035095) | 3.12884925 |
| 68 | DNA deamination (GO:0045006) | 3.11165200 |
| 69 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 3.11119847 |
| 70 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.11080151 |
| 71 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.11080151 |
| 72 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.11080151 |
| 73 | indolalkylamine metabolic process (GO:0006586) | 3.08817233 |
| 74 | epithelial cilium movement (GO:0003351) | 3.03461277 |
| 75 | cytochrome complex assembly (GO:0017004) | 3.00932972 |
| 76 | cellular protein complex disassembly (GO:0043624) | 3.00545353 |
| 77 | protein neddylation (GO:0045116) | 2.99196547 |
| 78 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.97786517 |
| 79 | xenobiotic catabolic process (GO:0042178) | 2.94530314 |
| 80 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.93395229 |
| 81 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.93395229 |
| 82 | mast cell activation (GO:0045576) | 2.92964045 |
| 83 | iron-sulfur cluster assembly (GO:0016226) | 2.91470186 |
| 84 | metallo-sulfur cluster assembly (GO:0031163) | 2.91470186 |
| 85 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.90736550 |
| 86 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.87919220 |
| 87 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.87141007 |
| 88 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.86271603 |
| 89 | translation (GO:0006412) | 2.84890524 |
| 90 | mast cell activation involved in immune response (GO:0002279) | 2.84421755 |
| 91 | mast cell degranulation (GO:0043303) | 2.84421755 |
| 92 | dopamine transport (GO:0015872) | 2.83446140 |
| 93 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.82934719 |
| 94 | regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) | 2.81167574 |
| 95 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.80646718 |
| 96 | response to pheromone (GO:0019236) | 2.76443719 |
| 97 | amine catabolic process (GO:0009310) | 2.75931810 |
| 98 | cellular biogenic amine catabolic process (GO:0042402) | 2.75931810 |
| 99 | viral life cycle (GO:0019058) | 2.75849567 |
| 100 | deoxyribose phosphate catabolic process (GO:0046386) | 2.74998081 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.55282784 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.11271553 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.98860116 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.89448518 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.63015244 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.31225329 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.19292564 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.12142850 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.00142686 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.88440579 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.86770785 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.84236150 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.83330176 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.81823271 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.36759684 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.32283986 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.26099355 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.09567854 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06257031 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.78141762 |
| 21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.76002870 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66292794 |
| 23 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.60284100 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.59136429 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.54058428 |
| 26 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.44564659 |
| 27 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.43582336 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.43279564 |
| 29 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.42999542 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.41651974 |
| 31 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.41614858 |
| 32 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.41227748 |
| 33 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.40005312 |
| 34 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.36855526 |
| 35 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.36068032 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.34652613 |
| 37 | NCOR_22424771_ChIP-Seq_293T_Human | 1.32012853 |
| 38 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30366730 |
| 39 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.29588924 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.27302751 |
| 41 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.24916427 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.23673366 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23643248 |
| 44 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.21315915 |
| 45 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20807306 |
| 46 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20394087 |
| 47 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18739591 |
| 48 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.17026774 |
| 49 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.16728602 |
| 50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.16504955 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16156716 |
| 52 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.15818439 |
| 53 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13809999 |
| 54 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.11687257 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10924171 |
| 56 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10924171 |
| 57 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.10913492 |
| 58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.10745272 |
| 59 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.10481259 |
| 60 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.09205625 |
| 61 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.08953115 |
| 62 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08732652 |
| 63 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.07677651 |
| 64 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.07374242 |
| 65 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.06690671 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.05395697 |
| 67 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05155670 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.04324972 |
| 69 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03027823 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02786616 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02786616 |
| 72 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.02552530 |
| 73 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02308756 |
| 74 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.02000741 |
| 75 | EWS_26573619_Chip-Seq_HEK293_Human | 1.00012308 |
| 76 | FUS_26573619_Chip-Seq_HEK293_Human | 0.99826187 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99544214 |
| 78 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99167958 |
| 79 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98864728 |
| 80 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98533783 |
| 81 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.97765693 |
| 82 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.96105131 |
| 83 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.95855445 |
| 84 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.95816458 |
| 85 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.95669547 |
| 86 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.93819407 |
| 87 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92786624 |
| 88 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.91632106 |
| 89 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.90870233 |
| 90 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.90074752 |
| 91 | ERA_21632823_ChIP-Seq_H3396_Human | 0.88639888 |
| 92 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.88552465 |
| 93 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87651122 |
| 94 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.86762990 |
| 95 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.86361161 |
| 96 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.86120729 |
| 97 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.85980183 |
| 98 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.85824333 |
| 99 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.84856702 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.84788292 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.64828680 |
| 2 | MP0003011_delayed_dark_adaptation | 3.49152211 |
| 3 | MP0002822_catalepsy | 3.26884157 |
| 4 | MP0005671_abnormal_response_to | 2.63476335 |
| 5 | MP0005451_abnormal_body_composition | 2.61775336 |
| 6 | MP0004147_increased_porphyrin_level | 2.59083869 |
| 7 | MP0001873_stomach_inflammation | 2.53485059 |
| 8 | MP0005645_abnormal_hypothalamus_physiol | 2.42659124 |
| 9 | MP0008872_abnormal_physiological_respon | 2.34622995 |
| 10 | MP0004142_abnormal_muscle_tone | 2.28141030 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.20529926 |
| 12 | MP0002653_abnormal_ependyma_morphology | 1.96017624 |
| 13 | MP0003880_abnormal_central_pattern | 1.91571504 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91221824 |
| 15 | MP0008995_early_reproductive_senescence | 1.85486451 |
| 16 | MP0006036_abnormal_mitochondrial_physio | 1.85202937 |
| 17 | MP0001905_abnormal_dopamine_level | 1.83528953 |
| 18 | MP0004742_abnormal_vestibular_system | 1.81692514 |
| 19 | MP0001529_abnormal_vocalization | 1.76966143 |
| 20 | MP0006292_abnormal_olfactory_placode | 1.70588594 |
| 21 | MP0002102_abnormal_ear_morphology | 1.69765894 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.65731092 |
| 23 | MP0009745_abnormal_behavioral_response | 1.65379373 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.57999362 |
| 25 | MP0002638_abnormal_pupillary_reflex | 1.55516031 |
| 26 | MP0010030_abnormal_orbit_morphology | 1.54000982 |
| 27 | MP0002736_abnormal_nociception_after | 1.52778138 |
| 28 | MP0005253_abnormal_eye_physiology | 1.49104125 |
| 29 | MP0001986_abnormal_taste_sensitivity | 1.39657079 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.39389656 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.39171327 |
| 32 | MP0003283_abnormal_digestive_organ | 1.32877208 |
| 33 | MP0000631_abnormal_neuroendocrine_gland | 1.31789948 |
| 34 | MP0002933_joint_inflammation | 1.31541318 |
| 35 | MP0010386_abnormal_urinary_bladder | 1.31064671 |
| 36 | MP0003763_abnormal_thymus_physiology | 1.28127857 |
| 37 | MP0001970_abnormal_pain_threshold | 1.26309231 |
| 38 | MP0003938_abnormal_ear_development | 1.25841691 |
| 39 | MP0003786_premature_aging | 1.24600017 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.24528054 |
| 41 | MP0002163_abnormal_gland_morphology | 1.23946245 |
| 42 | MP0009785_altered_susceptibility_to | 1.23588501 |
| 43 | MP0003806_abnormal_nucleotide_metabolis | 1.21124407 |
| 44 | MP0003638_abnormal_response/metabolism_ | 1.17974737 |
| 45 | MP0002272_abnormal_nervous_system | 1.17699365 |
| 46 | MP0005646_abnormal_pituitary_gland | 1.17060400 |
| 47 | MP0001968_abnormal_touch/_nociception | 1.13044927 |
| 48 | MP0000013_abnormal_adipose_tissue | 1.12418763 |
| 49 | MP0002735_abnormal_chemical_nociception | 1.12104985 |
| 50 | MP0008877_abnormal_DNA_methylation | 1.11483719 |
| 51 | MP0000049_abnormal_middle_ear | 1.01563667 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.00978534 |
| 53 | MP0001800_abnormal_humoral_immune | 1.00930420 |
| 54 | MP0003122_maternal_imprinting | 0.98420354 |
| 55 | MP0001919_abnormal_reproductive_system | 0.96492567 |
| 56 | MP0002006_tumorigenesis | 0.95049688 |
| 57 | MP0002557_abnormal_social/conspecific_i | 0.94828888 |
| 58 | MP0000372_irregular_coat_pigmentation | 0.94776919 |
| 59 | MP0002572_abnormal_emotion/affect_behav | 0.94293144 |
| 60 | MP0003724_increased_susceptibility_to | 0.94211620 |
| 61 | MP0003315_abnormal_perineum_morphology | 0.93791161 |
| 62 | MP0004133_heterotaxia | 0.93021210 |
| 63 | MP0002938_white_spotting | 0.92476393 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 0.90907925 |
| 65 | MP0002067_abnormal_sensory_capabilities | 0.89772551 |
| 66 | MP0005257_abnormal_intraocular_pressure | 0.89363302 |
| 67 | MP0002405_respiratory_system_inflammati | 0.89124719 |
| 68 | MP0005379_endocrine/exocrine_gland_phen | 0.88675884 |
| 69 | MP0002249_abnormal_larynx_morphology | 0.88394035 |
| 70 | MP0006035_abnormal_mitochondrial_morpho | 0.87162712 |
| 71 | MP0001486_abnormal_startle_reflex | 0.86992370 |
| 72 | MP0003718_maternal_effect | 0.86789509 |
| 73 | MP0000647_abnormal_sebaceous_gland | 0.83413410 |
| 74 | MP0002282_abnormal_trachea_morphology | 0.82729915 |
| 75 | MP0001119_abnormal_female_reproductive | 0.82481074 |
| 76 | MP0001663_abnormal_digestive_system | 0.80406006 |
| 77 | MP0005000_abnormal_immune_tolerance | 0.80345872 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.79899045 |
| 79 | MP0000026_abnormal_inner_ear | 0.79106117 |
| 80 | MP0005085_abnormal_gallbladder_physiolo | 0.78899444 |
| 81 | MP0000538_abnormal_urinary_bladder | 0.78664534 |
| 82 | MP0002723_abnormal_immune_serum | 0.77005783 |
| 83 | MP0002063_abnormal_learning/memory/cond | 0.76943502 |
| 84 | MP0002733_abnormal_thermal_nociception | 0.76104100 |
| 85 | MP0002210_abnormal_sex_determination | 0.73608251 |
| 86 | MP0009764_decreased_sensitivity_to | 0.73587584 |
| 87 | MP0005389_reproductive_system_phenotype | 0.73403181 |
| 88 | MP0002837_dystrophic_cardiac_calcinosis | 0.72988706 |
| 89 | MP0005381_digestive/alimentary_phenotyp | 0.72172187 |
| 90 | MP0003635_abnormal_synaptic_transmissio | 0.72093663 |
| 91 | MP0000653_abnormal_sex_gland | 0.72025527 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.71977146 |
| 93 | MP0008058_abnormal_DNA_repair | 0.70171383 |
| 94 | MP0001929_abnormal_gametogenesis | 0.69217064 |
| 95 | MP0001440_abnormal_grooming_behavior | 0.68528456 |
| 96 | MP0001764_abnormal_homeostasis | 0.68302953 |
| 97 | MP0002095_abnormal_skin_pigmentation | 0.67203165 |
| 98 | MP0001145_abnormal_male_reproductive | 0.67021500 |
| 99 | MP0009046_muscle_twitch | 0.66672164 |
| 100 | MP0005195_abnormal_posterior_eye | 0.66221137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.87172965 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.53633356 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.32706102 |
| 4 | Aplastic anemia (HP:0001915) | 4.28835272 |
| 5 | Colon cancer (HP:0003003) | 4.10087708 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.09290944 |
| 7 | Increased CSF lactate (HP:0002490) | 3.96071994 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.81881653 |
| 9 | Abnormality of B cell number (HP:0010975) | 3.75389187 |
| 10 | Acute encephalopathy (HP:0006846) | 3.74166486 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.65365014 |
| 12 | Hepatic necrosis (HP:0002605) | 3.50162120 |
| 13 | Stomach cancer (HP:0012126) | 3.49217197 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.37878770 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.10398343 |
| 16 | Septo-optic dysplasia (HP:0100842) | 3.01841671 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 2.95820710 |
| 18 | Molar tooth sign on MRI (HP:0002419) | 2.95820710 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 2.92188212 |
| 20 | Optic disc pallor (HP:0000543) | 2.92050614 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 2.83509083 |
| 22 | IgG deficiency (HP:0004315) | 2.83417563 |
| 23 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.79418847 |
| 24 | Cerebral edema (HP:0002181) | 2.76769769 |
| 25 | Retinal dysplasia (HP:0007973) | 2.68814038 |
| 26 | True hermaphroditism (HP:0010459) | 2.65350492 |
| 27 | Increased intramyocellular lipid droplets (HP:0012240) | 2.63904816 |
| 28 | Increased serum lactate (HP:0002151) | 2.63503076 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.63232277 |
| 30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.63232277 |
| 31 | Sensory axonal neuropathy (HP:0003390) | 2.60716155 |
| 32 | Abolished electroretinogram (ERG) (HP:0000550) | 2.51092389 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.49330464 |
| 34 | Rough bone trabeculation (HP:0100670) | 2.46561320 |
| 35 | Exertional dyspnea (HP:0002875) | 2.44246378 |
| 36 | Pancreatic cysts (HP:0001737) | 2.42285692 |
| 37 | Autoimmune thrombocytopenia (HP:0001973) | 2.41499799 |
| 38 | Respiratory failure (HP:0002878) | 2.33661577 |
| 39 | Leukodystrophy (HP:0002415) | 2.33626462 |
| 40 | Constricted visual fields (HP:0001133) | 2.32773010 |
| 41 | Lactic acidosis (HP:0003128) | 2.30783390 |
| 42 | Increased IgM level (HP:0003496) | 2.30230363 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.29360791 |
| 44 | Congenital, generalized hypertrichosis (HP:0004540) | 2.28731479 |
| 45 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.27482524 |
| 46 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.24100007 |
| 47 | Medial flaring of the eyebrow (HP:0010747) | 2.23879854 |
| 48 | Reticulocytopenia (HP:0001896) | 2.23671095 |
| 49 | Oral leukoplakia (HP:0002745) | 2.22500803 |
| 50 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.21220645 |
| 51 | Generalized aminoaciduria (HP:0002909) | 2.19359771 |
| 52 | Type II lissencephaly (HP:0007260) | 2.16751072 |
| 53 | Pancytopenia (HP:0001876) | 2.15530621 |
| 54 | Attenuation of retinal blood vessels (HP:0007843) | 2.14673065 |
| 55 | Limb dystonia (HP:0002451) | 2.14467046 |
| 56 | Hypoplasia of the pons (HP:0012110) | 2.14432166 |
| 57 | Submucous cleft hard palate (HP:0000176) | 2.13758410 |
| 58 | B lymphocytopenia (HP:0010976) | 2.13223283 |
| 59 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.11905685 |
| 60 | Methylmalonic acidemia (HP:0002912) | 2.11375968 |
| 61 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.07229572 |
| 62 | Testicular atrophy (HP:0000029) | 2.06790648 |
| 63 | Cerebellar dysplasia (HP:0007033) | 2.06496780 |
| 64 | Type 2 muscle fiber atrophy (HP:0003554) | 2.05886632 |
| 65 | Dyschromatopsia (HP:0007641) | 2.05557338 |
| 66 | Abnormality of the pons (HP:0007361) | 2.04566944 |
| 67 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.02703313 |
| 68 | Pendular nystagmus (HP:0012043) | 2.00442688 |
| 69 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.99757833 |
| 70 | Optic nerve hypoplasia (HP:0000609) | 1.99151822 |
| 71 | Stenosis of the external auditory canal (HP:0000402) | 1.98613000 |
| 72 | Macrocytic anemia (HP:0001972) | 1.98144384 |
| 73 | Abnormality of T cell number (HP:0011839) | 1.96210698 |
| 74 | Lethargy (HP:0001254) | 1.96207529 |
| 75 | Increased muscle lipid content (HP:0009058) | 1.96188823 |
| 76 | Autoimmune hemolytic anemia (HP:0001890) | 1.94868527 |
| 77 | Absent septum pellucidum (HP:0001331) | 1.91196032 |
| 78 | Rib fusion (HP:0000902) | 1.91185575 |
| 79 | Abnormality of eosinophils (HP:0001879) | 1.88371119 |
| 80 | Exercise intolerance (HP:0003546) | 1.87680519 |
| 81 | Microretrognathia (HP:0000308) | 1.86507776 |
| 82 | Sclerocornea (HP:0000647) | 1.84678578 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.84437848 |
| 84 | Abnormality of the labia minora (HP:0012880) | 1.83377931 |
| 85 | Abnormal trabecular bone morphology (HP:0100671) | 1.83025745 |
| 86 | Parakeratosis (HP:0001036) | 1.79147705 |
| 87 | Anencephaly (HP:0002323) | 1.78615523 |
| 88 | Methylmalonic aciduria (HP:0012120) | 1.77830158 |
| 89 | Decreased central vision (HP:0007663) | 1.76332925 |
| 90 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.76299726 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.75521456 |
| 92 | Severe visual impairment (HP:0001141) | 1.70356425 |
| 93 | Metabolic alkalosis (HP:0200114) | 1.69892885 |
| 94 | Flat capital femoral epiphysis (HP:0003370) | 1.69703355 |
| 95 | Myokymia (HP:0002411) | 1.69244399 |
| 96 | Increased corneal curvature (HP:0100692) | 1.68373432 |
| 97 | Keratoconus (HP:0000563) | 1.68373432 |
| 98 | Choroideremia (HP:0001139) | 1.66925689 |
| 99 | Severe combined immunodeficiency (HP:0004430) | 1.66190277 |
| 100 | Increased serum pyruvate (HP:0003542) | 1.65525961 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 3.77619006 |
| 2 | CDK19 | 3.70949464 |
| 3 | VRK2 | 3.19751701 |
| 4 | MAP4K2 | 2.86542820 |
| 5 | CAMKK2 | 2.73107297 |
| 6 | NUAK1 | 2.71507746 |
| 7 | PINK1 | 2.56228489 |
| 8 | TAOK3 | 2.29568385 |
| 9 | MAP3K12 | 2.25315983 |
| 10 | PASK | 2.20295343 |
| 11 | BCKDK | 2.18587925 |
| 12 | STK16 | 2.16394734 |
| 13 | TESK2 | 1.81459936 |
| 14 | BUB1 | 1.78747565 |
| 15 | KDR | 1.78462256 |
| 16 | CDC7 | 1.73520254 |
| 17 | TLK1 | 1.69431323 |
| 18 | KIT | 1.65141477 |
| 19 | ERBB3 | 1.64774077 |
| 20 | CDK8 | 1.57999277 |
| 21 | NME1 | 1.46142942 |
| 22 | CSF1R | 1.45638462 |
| 23 | VRK1 | 1.45054375 |
| 24 | CAMKK1 | 1.41232207 |
| 25 | LIMK1 | 1.40045886 |
| 26 | DYRK2 | 1.40028725 |
| 27 | WNK3 | 1.19167830 |
| 28 | TXK | 1.18880717 |
| 29 | FLT3 | 1.17395825 |
| 30 | MAP2K7 | 1.15897405 |
| 31 | MAP3K4 | 1.15868152 |
| 32 | PRKD3 | 1.15030912 |
| 33 | MYLK | 1.14096975 |
| 34 | MST4 | 1.09937733 |
| 35 | GRK1 | 1.09030787 |
| 36 | TESK1 | 1.06642700 |
| 37 | CCNB1 | 1.01185063 |
| 38 | DAPK3 | 0.99961745 |
| 39 | BMPR2 | 0.97510307 |
| 40 | EPHA4 | 0.94417117 |
| 41 | PLK4 | 0.92313754 |
| 42 | ZAK | 0.91888969 |
| 43 | MAPK13 | 0.88427435 |
| 44 | NTRK2 | 0.87100019 |
| 45 | TEC | 0.84802657 |
| 46 | ILK | 0.84400075 |
| 47 | PIK3CG | 0.81343936 |
| 48 | SRPK1 | 0.80345731 |
| 49 | BRSK1 | 0.76460279 |
| 50 | SCYL2 | 0.74689666 |
| 51 | SIK2 | 0.72958225 |
| 52 | TAOK2 | 0.67180533 |
| 53 | NME2 | 0.66567195 |
| 54 | TAF1 | 0.66509328 |
| 55 | SIK3 | 0.66327162 |
| 56 | ABL2 | 0.65444972 |
| 57 | PIM2 | 0.64269784 |
| 58 | DAPK1 | 0.64107885 |
| 59 | CSNK1G3 | 0.62682887 |
| 60 | INSRR | 0.61432570 |
| 61 | GRK5 | 0.60955157 |
| 62 | ITK | 0.60214791 |
| 63 | LATS1 | 0.57890031 |
| 64 | TRIM28 | 0.56477886 |
| 65 | GRK7 | 0.55995327 |
| 66 | CLK1 | 0.55772531 |
| 67 | SYK | 0.55286632 |
| 68 | CSNK1G1 | 0.54774263 |
| 69 | LRRK2 | 0.54208329 |
| 70 | NEK1 | 0.53796224 |
| 71 | EPHB2 | 0.53581266 |
| 72 | CSNK1G2 | 0.52279674 |
| 73 | BRSK2 | 0.51851736 |
| 74 | TSSK6 | 0.50483072 |
| 75 | PKN1 | 0.50391539 |
| 76 | STK38L | 0.50345572 |
| 77 | OXSR1 | 0.49496061 |
| 78 | PLK2 | 0.49078588 |
| 79 | PRKCG | 0.48001537 |
| 80 | OBSCN | 0.47907757 |
| 81 | PBK | 0.47775475 |
| 82 | PLK3 | 0.46982745 |
| 83 | PHKG1 | 0.45973701 |
| 84 | PHKG2 | 0.45973701 |
| 85 | PRKCI | 0.44715337 |
| 86 | MARK1 | 0.44420909 |
| 87 | PRKACA | 0.44002650 |
| 88 | TIE1 | 0.43106450 |
| 89 | LCK | 0.42332162 |
| 90 | RPS6KA5 | 0.42059106 |
| 91 | PRKG1 | 0.40548585 |
| 92 | LYN | 0.38333289 |
| 93 | GRK6 | 0.37889076 |
| 94 | CDK11A | 0.36249954 |
| 95 | PRKCE | 0.35486480 |
| 96 | WNK4 | 0.35196154 |
| 97 | MAP3K11 | 0.35162106 |
| 98 | IGF1R | 0.35115713 |
| 99 | CSNK2A1 | 0.34981689 |
| 100 | AURKB | 0.34852204 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.07863108 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.03926641 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.63334329 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.44800857 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.42994055 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.67542326 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.41924547 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.40400457 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.35491962 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.23294474 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.12544091 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.09993422 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.06818290 |
| 14 | Protein export_Homo sapiens_hsa03060 | 2.02252318 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.97948184 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.96967725 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.91787162 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.84135097 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.83275706 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79668757 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70574888 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.67397963 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.63535432 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.60976402 |
| 25 | Base excision repair_Homo sapiens_hsa03410 | 1.56211401 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.50307835 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.50283495 |
| 28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.49709209 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.37489479 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.26030818 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24082996 |
| 32 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.20668609 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.19184568 |
| 34 | DNA replication_Homo sapiens_hsa03030 | 1.16387032 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 1.11747591 |
| 36 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.11446184 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.05021362 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04130899 |
| 39 | Olfactory transduction_Homo sapiens_hsa04740 | 1.01425088 |
| 40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.99460913 |
| 41 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.94235886 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.87124229 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84522575 |
| 44 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.82552491 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.82395812 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 0.82321970 |
| 47 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.80642387 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.78986523 |
| 49 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78112707 |
| 50 | Nicotine addiction_Homo sapiens_hsa05033 | 0.77832665 |
| 51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.77103992 |
| 52 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.76001433 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.75941943 |
| 54 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.74695239 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.72880529 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.72188799 |
| 57 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.72048894 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71397774 |
| 59 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71281764 |
| 60 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67506099 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.66105830 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62579185 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61176624 |
| 64 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.60172777 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57768775 |
| 66 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.57732698 |
| 67 | Sulfur relay system_Homo sapiens_hsa04122 | 0.56453065 |
| 68 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.56230751 |
| 69 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.52739786 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.52298660 |
| 71 | Salivary secretion_Homo sapiens_hsa04970 | 0.51811541 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51343930 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.51064877 |
| 74 | Leishmaniasis_Homo sapiens_hsa05140 | 0.50726553 |
| 75 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.48260881 |
| 76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.47744389 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.46817217 |
| 78 | Taste transduction_Homo sapiens_hsa04742 | 0.42410321 |
| 79 | Morphine addiction_Homo sapiens_hsa05032 | 0.42169482 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39872529 |
| 81 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.39491577 |
| 82 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.39269299 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.37366648 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35660453 |
| 85 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.35588498 |
| 86 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.35410349 |
| 87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.34040537 |
| 88 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.33499528 |
| 89 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29098307 |
| 90 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.27967473 |
| 91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.27012747 |
| 92 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.26434738 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.26431430 |
| 94 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.23674229 |
| 95 | Phagosome_Homo sapiens_hsa04145 | 0.23625730 |
| 96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.23600294 |
| 97 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.22745753 |
| 98 | Basal transcription factors_Homo sapiens_hsa03022 | 0.21152076 |
| 99 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.21056447 |
| 100 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.20130240 |

