

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.31419559 |
| 2 | cytidine deamination (GO:0009972) | 6.67994584 |
| 3 | cytidine metabolic process (GO:0046087) | 6.67994584 |
| 4 | cytidine catabolic process (GO:0006216) | 6.67994584 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.80889768 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.54422019 |
| 7 | proteasome assembly (GO:0043248) | 4.55419968 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.91596995 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.71511939 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 3.71511939 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.70204723 |
| 12 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.69994943 |
| 13 | protein neddylation (GO:0045116) | 3.63467352 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55751490 |
| 15 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.54834853 |
| 16 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.54170836 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.50483163 |
| 18 | protein complex biogenesis (GO:0070271) | 3.48396060 |
| 19 | respiratory electron transport chain (GO:0022904) | 3.44770195 |
| 20 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.43355464 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.43355464 |
| 22 | cullin deneddylation (GO:0010388) | 3.42416884 |
| 23 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.42292899 |
| 24 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.42292899 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.42292899 |
| 26 | electron transport chain (GO:0022900) | 3.42018052 |
| 27 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.36725812 |
| 28 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.36024070 |
| 29 | negative regulation of ligase activity (GO:0051352) | 3.29030174 |
| 30 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.29030174 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.28457488 |
| 32 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.28394008 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.26199414 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.26199414 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.26199414 |
| 36 | chaperone-mediated protein transport (GO:0072321) | 3.25100490 |
| 37 | negative regulation of T cell apoptotic process (GO:0070233) | 3.24332040 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.22458320 |
| 39 | platelet dense granule organization (GO:0060155) | 3.20949060 |
| 40 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.20896605 |
| 41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.20848837 |
| 42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.20848837 |
| 43 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.20333000 |
| 44 | protein deneddylation (GO:0000338) | 3.16937557 |
| 45 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.15665961 |
| 46 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.14151502 |
| 47 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.13637967 |
| 48 | sequestering of actin monomers (GO:0042989) | 3.07262688 |
| 49 | ubiquinone biosynthetic process (GO:0006744) | 3.03366864 |
| 50 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.01870218 |
| 51 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.01710302 |
| 52 | positive regulation of B cell differentiation (GO:0045579) | 3.00358553 |
| 53 | respiratory chain complex IV assembly (GO:0008535) | 2.98235191 |
| 54 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.93862668 |
| 55 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.90686073 |
| 56 | iron-sulfur cluster assembly (GO:0016226) | 2.89769008 |
| 57 | metallo-sulfur cluster assembly (GO:0031163) | 2.89769008 |
| 58 | regulation of mitochondrial translation (GO:0070129) | 2.88979655 |
| 59 | base-excision repair, AP site formation (GO:0006285) | 2.88364681 |
| 60 | DNA demethylation (GO:0080111) | 2.86144135 |
| 61 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.85031829 |
| 62 | regulation of regulatory T cell differentiation (GO:0045589) | 2.83224247 |
| 63 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.82271671 |
| 64 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.82271671 |
| 65 | negative T cell selection (GO:0043383) | 2.81029182 |
| 66 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.77583330 |
| 67 | positive regulation of cell cycle arrest (GO:0071158) | 2.76805659 |
| 68 | positive regulation of ligase activity (GO:0051351) | 2.76383816 |
| 69 | ubiquinone metabolic process (GO:0006743) | 2.75043469 |
| 70 | negative regulation by host of viral transcription (GO:0043922) | 2.74153670 |
| 71 | regulation of B cell differentiation (GO:0045577) | 2.73890386 |
| 72 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.73603649 |
| 73 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.72958951 |
| 74 | cytochrome complex assembly (GO:0017004) | 2.71466972 |
| 75 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.68293784 |
| 76 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.66666895 |
| 77 | glucosamine-containing compound catabolic process (GO:1901072) | 2.65811124 |
| 78 | regulation of cellular amine metabolic process (GO:0033238) | 2.65584570 |
| 79 | T cell migration (GO:0072678) | 2.62618898 |
| 80 | quinone biosynthetic process (GO:1901663) | 2.60368769 |
| 81 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.59661405 |
| 82 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.59514799 |
| 83 | tryptophan catabolic process (GO:0006569) | 2.59403736 |
| 84 | indole-containing compound catabolic process (GO:0042436) | 2.59403736 |
| 85 | indolalkylamine catabolic process (GO:0046218) | 2.59403736 |
| 86 | actin nucleation (GO:0045010) | 2.58660542 |
| 87 | positive regulation of defense response to virus by host (GO:0002230) | 2.57502092 |
| 88 | branched-chain amino acid catabolic process (GO:0009083) | 2.55746516 |
| 89 | cellular response to interleukin-15 (GO:0071350) | 2.55060827 |
| 90 | positive thymic T cell selection (GO:0045059) | 2.54411479 |
| 91 | rRNA modification (GO:0000154) | 2.53880912 |
| 92 | deoxyribonucleotide catabolic process (GO:0009264) | 2.53184315 |
| 93 | pseudouridine synthesis (GO:0001522) | 2.53033174 |
| 94 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.52924749 |
| 95 | protein targeting to mitochondrion (GO:0006626) | 2.52872628 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.51853376 |
| 97 | DNA dealkylation (GO:0035510) | 2.51614612 |
| 98 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.50963972 |
| 99 | positive T cell selection (GO:0043368) | 2.49900391 |
| 100 | positive regulation of prostaglandin secretion (GO:0032308) | 2.49704756 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.86988671 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.36067054 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.95604065 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.89307362 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.59571139 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.51508757 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.34690040 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.28991355 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.08854338 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.68565877 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.61982840 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.43810041 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.39693709 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.36144898 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.23178837 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21300838 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.19875991 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.18723272 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.16521581 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.10621476 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00656423 |
| 22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.99801034 |
| 23 | VDR_22108803_ChIP-Seq_LS180_Human | 1.99518833 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.91944276 |
| 25 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.77919267 |
| 26 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.77526336 |
| 27 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.76936225 |
| 28 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.75828994 |
| 29 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65777146 |
| 30 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.65357952 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.63248451 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.60145066 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.56184847 |
| 34 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.53582869 |
| 35 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.51319848 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.48956098 |
| 37 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.43685249 |
| 38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.42233844 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40869523 |
| 40 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40134443 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.39544392 |
| 42 | GATA3_26560356_Chip-Seq_TH2_Human | 1.38228347 |
| 43 | MYB_26560356_Chip-Seq_TH2_Human | 1.37669331 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.34887785 |
| 45 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.34489861 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34329101 |
| 47 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28425774 |
| 48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.28177892 |
| 49 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.27752742 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27209190 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26072505 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25748767 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25748767 |
| 54 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.25567473 |
| 55 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.22789314 |
| 56 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22781790 |
| 57 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22475237 |
| 58 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.20734223 |
| 59 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.19688482 |
| 60 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19346741 |
| 61 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19109853 |
| 62 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17024687 |
| 63 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16274404 |
| 64 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14211842 |
| 65 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.14073364 |
| 66 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13863575 |
| 67 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11180544 |
| 68 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10569024 |
| 69 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.10157299 |
| 70 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.09460538 |
| 71 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.07778174 |
| 72 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.07631699 |
| 73 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.07159126 |
| 74 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.06883898 |
| 75 | NCOR_22424771_ChIP-Seq_293T_Human | 1.06196150 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.06190301 |
| 77 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.04132743 |
| 78 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.03777014 |
| 79 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.03727601 |
| 80 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.03566192 |
| 81 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03022165 |
| 82 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.01827584 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.96857503 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.95900243 |
| 85 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95868760 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95868760 |
| 87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.95432011 |
| 88 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.95038608 |
| 89 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.94993573 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.94884473 |
| 91 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.93946758 |
| 92 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93171201 |
| 93 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92931505 |
| 94 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.91507484 |
| 95 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.90260147 |
| 96 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.90018915 |
| 97 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89142327 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88702096 |
| 99 | MYB_26560356_Chip-Seq_TH1_Human | 0.88601881 |
| 100 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87625718 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.30335506 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.74359599 |
| 3 | MP0004147_increased_porphyrin_level | 3.04574801 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.96612602 |
| 5 | MP0009785_altered_susceptibility_to | 2.49258653 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 2.25972008 |
| 7 | MP0003786_premature_aging | 2.18987980 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.17140440 |
| 9 | MP0002736_abnormal_nociception_after | 2.15246197 |
| 10 | MP0006036_abnormal_mitochondrial_physio | 2.09211055 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.06841790 |
| 12 | MP0002102_abnormal_ear_morphology | 2.01166363 |
| 13 | MP0001800_abnormal_humoral_immune | 2.01113484 |
| 14 | MP0005646_abnormal_pituitary_gland | 1.99625842 |
| 15 | MP0005000_abnormal_immune_tolerance | 1.93052088 |
| 16 | MP0003763_abnormal_thymus_physiology | 1.92089537 |
| 17 | MP0008058_abnormal_DNA_repair | 1.87378939 |
| 18 | MP0003724_increased_susceptibility_to | 1.82149770 |
| 19 | MP0003195_calcinosis | 1.82049217 |
| 20 | MP0005360_urolithiasis | 1.81190144 |
| 21 | MP0002420_abnormal_adaptive_immunity | 1.75834164 |
| 22 | MP0008872_abnormal_physiological_respon | 1.73580121 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.71743109 |
| 24 | MP0001819_abnormal_immune_cell | 1.70437842 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.67886733 |
| 26 | MP0002723_abnormal_immune_serum | 1.64712440 |
| 27 | MP0009697_abnormal_copulation | 1.63352397 |
| 28 | MP0005025_abnormal_response_to | 1.61708954 |
| 29 | MP0006082_CNS_inflammation | 1.58713118 |
| 30 | MP0001853_heart_inflammation | 1.57471613 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.56247741 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.49672058 |
| 33 | MP0003252_abnormal_bile_duct | 1.48813759 |
| 34 | MP0010386_abnormal_urinary_bladder | 1.48032327 |
| 35 | MP0001790_abnormal_immune_system | 1.47131402 |
| 36 | MP0005387_immune_system_phenotype | 1.47131402 |
| 37 | MP0000685_abnormal_immune_system | 1.46227987 |
| 38 | MP0002452_abnormal_antigen_presenting | 1.45956515 |
| 39 | MP0003866_abnormal_defecation | 1.44081557 |
| 40 | MP0002876_abnormal_thyroid_physiology | 1.44028620 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.43456809 |
| 42 | MP0003693_abnormal_embryo_hatching | 1.40684740 |
| 43 | MP0001764_abnormal_homeostasis | 1.39807321 |
| 44 | MP0003183_abnormal_peptide_metabolism | 1.37586850 |
| 45 | MP0000716_abnormal_immune_system | 1.36809269 |
| 46 | MP0002398_abnormal_bone_marrow | 1.35481265 |
| 47 | MP0003186_abnormal_redox_activity | 1.34461114 |
| 48 | MP0006276_abnormal_autonomic_nervous | 1.31023647 |
| 49 | MP0003806_abnormal_nucleotide_metabolis | 1.29440532 |
| 50 | MP0000689_abnormal_spleen_morphology | 1.28098230 |
| 51 | MP0006292_abnormal_olfactory_placode | 1.26702453 |
| 52 | MP0002132_abnormal_respiratory_system | 1.24362804 |
| 53 | MP0005085_abnormal_gallbladder_physiolo | 1.23517982 |
| 54 | MP0002722_abnormal_immune_system | 1.20046958 |
| 55 | MP0005075_abnormal_melanosome_morpholog | 1.19216387 |
| 56 | MP0002405_respiratory_system_inflammati | 1.18320745 |
| 57 | MP0002837_dystrophic_cardiac_calcinosis | 1.16794900 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 1.15379837 |
| 59 | MP0005410_abnormal_fertilization | 1.15051239 |
| 60 | MP0000372_irregular_coat_pigmentation | 1.14121059 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 1.14017806 |
| 62 | MP0001845_abnormal_inflammatory_respons | 1.13879843 |
| 63 | MP0000703_abnormal_thymus_morphology | 1.11081960 |
| 64 | MP0010155_abnormal_intestine_physiology | 1.10974428 |
| 65 | MP0004145_abnormal_muscle_electrophysio | 1.09793397 |
| 66 | MP0002419_abnormal_innate_immunity | 1.08948208 |
| 67 | MP0003718_maternal_effect | 1.07270010 |
| 68 | MP0002429_abnormal_blood_cell | 1.05980916 |
| 69 | MP0001919_abnormal_reproductive_system | 1.05471476 |
| 70 | MP0003880_abnormal_central_pattern | 1.05467449 |
| 71 | MP0002166_altered_tumor_susceptibility | 1.05338597 |
| 72 | MP0005636_abnormal_mineral_homeostasis | 1.04956654 |
| 73 | MP0008469_abnormal_protein_level | 1.02634604 |
| 74 | MP0010094_abnormal_chromosome_stability | 1.02544914 |
| 75 | MP0000465_gastrointestinal_hemorrhage | 1.00676774 |
| 76 | MP0005464_abnormal_platelet_physiology | 0.96524137 |
| 77 | MP0003011_delayed_dark_adaptation | 0.93715574 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.90387730 |
| 79 | MP0001501_abnormal_sleep_pattern | 0.90171172 |
| 80 | MP0002653_abnormal_ependyma_morphology | 0.88216662 |
| 81 | MP0001873_stomach_inflammation | 0.87907246 |
| 82 | MP0005365_abnormal_bile_salt | 0.87127011 |
| 83 | MP0008007_abnormal_cellular_replicative | 0.86739502 |
| 84 | MP0008789_abnormal_olfactory_epithelium | 0.86448563 |
| 85 | MP0002006_tumorigenesis | 0.86282586 |
| 86 | MP0009764_decreased_sensitivity_to | 0.85652116 |
| 87 | MP0003436_decreased_susceptibility_to | 0.84975417 |
| 88 | MP0002139_abnormal_hepatobiliary_system | 0.83654181 |
| 89 | MP0001905_abnormal_dopamine_level | 0.83220799 |
| 90 | MP0001986_abnormal_taste_sensitivity | 0.82690382 |
| 91 | MP0004142_abnormal_muscle_tone | 0.81204115 |
| 92 | MP0002019_abnormal_tumor_incidence | 0.79442021 |
| 93 | MP0002163_abnormal_gland_morphology | 0.78516364 |
| 94 | MP0002735_abnormal_chemical_nociception | 0.77775461 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.77631310 |
| 96 | MP0005319_abnormal_enzyme/_coenzyme | 0.76078184 |
| 97 | MP0004885_abnormal_endolymph | 0.73981904 |
| 98 | MP0009643_abnormal_urine_homeostasis | 0.73630316 |
| 99 | MP0005389_reproductive_system_phenotype | 0.73365832 |
| 100 | MP0005253_abnormal_eye_physiology | 0.71542719 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.44188724 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.15090606 |
| 3 | Abnormality of B cell number (HP:0010975) | 4.04036547 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 4.03498708 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.97155457 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.90606965 |
| 7 | Hypoproteinemia (HP:0003075) | 3.86972276 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.76354169 |
| 9 | Acute encephalopathy (HP:0006846) | 3.76278662 |
| 10 | Abnormality of T cell number (HP:0011839) | 3.75540474 |
| 11 | Increased CSF lactate (HP:0002490) | 3.60975112 |
| 12 | Hepatic necrosis (HP:0002605) | 3.55265837 |
| 13 | Eosinophilia (HP:0001880) | 3.42855604 |
| 14 | Cerebral edema (HP:0002181) | 3.42740222 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.38852102 |
| 16 | Panhypogammaglobulinemia (HP:0003139) | 3.38033210 |
| 17 | Autoimmune hemolytic anemia (HP:0001890) | 3.36143830 |
| 18 | T lymphocytopenia (HP:0005403) | 3.27370752 |
| 19 | Abnormality of eosinophils (HP:0001879) | 3.23840485 |
| 20 | Autoimmune thrombocytopenia (HP:0001973) | 3.15588569 |
| 21 | Combined immunodeficiency (HP:0005387) | 3.14337477 |
| 22 | IgG deficiency (HP:0004315) | 3.00873565 |
| 23 | Thyroiditis (HP:0100646) | 2.99371993 |
| 24 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.87587298 |
| 25 | B lymphocytopenia (HP:0010976) | 2.85200286 |
| 26 | Granulocytopenia (HP:0001913) | 2.84429976 |
| 27 | Oral leukoplakia (HP:0002745) | 2.83460406 |
| 28 | Increased IgM level (HP:0003496) | 2.79128655 |
| 29 | 3-Methylglutaconic aciduria (HP:0003535) | 2.75887941 |
| 30 | Congenital stationary night blindness (HP:0007642) | 2.73598318 |
| 31 | Increased hepatocellular lipid droplets (HP:0006565) | 2.71783422 |
| 32 | Abnormality of T cells (HP:0002843) | 2.71177718 |
| 33 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.65459396 |
| 34 | Pancytopenia (HP:0001876) | 2.61185764 |
| 35 | Increased serum lactate (HP:0002151) | 2.59165327 |
| 36 | Lactic acidosis (HP:0003128) | 2.57346847 |
| 37 | Optic disc pallor (HP:0000543) | 2.55596912 |
| 38 | Stomach cancer (HP:0012126) | 2.54668270 |
| 39 | Abnormality of the prostate (HP:0008775) | 2.54387932 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.54120439 |
| 41 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.53788384 |
| 42 | Generalized aminoaciduria (HP:0002909) | 2.53440595 |
| 43 | Hypoplasia of the thymus (HP:0000778) | 2.49592928 |
| 44 | Lipid accumulation in hepatocytes (HP:0006561) | 2.48464493 |
| 45 | Abolished electroretinogram (ERG) (HP:0000550) | 2.40288599 |
| 46 | Lethargy (HP:0001254) | 2.39339874 |
| 47 | Methylmalonic acidemia (HP:0002912) | 2.39314255 |
| 48 | Hyperglycinuria (HP:0003108) | 2.37748032 |
| 49 | Constricted visual fields (HP:0001133) | 2.36938962 |
| 50 | Type I transferrin isoform profile (HP:0003642) | 2.36847251 |
| 51 | Reduced antithrombin III activity (HP:0001976) | 2.36634440 |
| 52 | Respiratory failure (HP:0002878) | 2.34160461 |
| 53 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.32941515 |
| 54 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.32941515 |
| 55 | Pancreatic cysts (HP:0001737) | 2.29303059 |
| 56 | Attenuation of retinal blood vessels (HP:0007843) | 2.28487613 |
| 57 | Methylmalonic aciduria (HP:0012120) | 2.24680345 |
| 58 | Renal Fanconi syndrome (HP:0001994) | 2.23055513 |
| 59 | Abnormality of glycine metabolism (HP:0010895) | 2.21130146 |
| 60 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.21130146 |
| 61 | True hermaphroditism (HP:0010459) | 2.20896012 |
| 62 | Agammaglobulinemia (HP:0004432) | 2.20713638 |
| 63 | Congenital, generalized hypertrichosis (HP:0004540) | 2.19208801 |
| 64 | Decreased central vision (HP:0007663) | 2.12239799 |
| 65 | Leukocytosis (HP:0001974) | 2.12066945 |
| 66 | Stomatitis (HP:0010280) | 2.09761508 |
| 67 | Chronic diarrhea (HP:0002028) | 2.09746737 |
| 68 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.09186455 |
| 69 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.02598424 |
| 70 | Increased muscle lipid content (HP:0009058) | 2.02364459 |
| 71 | Abnormality of T cell physiology (HP:0011840) | 2.01297330 |
| 72 | CNS demyelination (HP:0007305) | 1.98815970 |
| 73 | Dry hair (HP:0011359) | 1.98211591 |
| 74 | Hyperglycinemia (HP:0002154) | 1.95850990 |
| 75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.95633202 |
| 76 | Dicarboxylic aciduria (HP:0003215) | 1.95633202 |
| 77 | Encephalitis (HP:0002383) | 1.93850323 |
| 78 | Abnormal protein glycosylation (HP:0012346) | 1.93083575 |
| 79 | Abnormal glycosylation (HP:0012345) | 1.93083575 |
| 80 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93083575 |
| 81 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93083575 |
| 82 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.92939813 |
| 83 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.90343000 |
| 84 | Exercise intolerance (HP:0003546) | 1.89318036 |
| 85 | Colon cancer (HP:0003003) | 1.86435583 |
| 86 | Renal cortical cysts (HP:0000803) | 1.82473299 |
| 87 | Abnormality of methionine metabolism (HP:0010901) | 1.80898013 |
| 88 | Pancreatic fibrosis (HP:0100732) | 1.79730588 |
| 89 | Meningitis (HP:0001287) | 1.78767584 |
| 90 | Abnormality of urine glucose concentration (HP:0011016) | 1.77134628 |
| 91 | Glycosuria (HP:0003076) | 1.77134628 |
| 92 | Abnormality of serum amino acid levels (HP:0003112) | 1.76924252 |
| 93 | Neutropenia (HP:0001875) | 1.74922337 |
| 94 | Erythroderma (HP:0001019) | 1.74798586 |
| 95 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.71940847 |
| 96 | Pendular nystagmus (HP:0012043) | 1.67432693 |
| 97 | Retrobulbar optic neuritis (HP:0100654) | 1.67175412 |
| 98 | Optic neuritis (HP:0100653) | 1.67175412 |
| 99 | Leukodystrophy (HP:0002415) | 1.66582297 |
| 100 | Chronic sinusitis (HP:0011109) | 1.65591956 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.51089868 |
| 2 | TXK | 3.40644318 |
| 3 | KDR | 3.27807801 |
| 4 | BUB1 | 3.21526384 |
| 5 | BCKDK | 3.19799069 |
| 6 | TESK2 | 2.51666427 |
| 7 | MAP3K12 | 2.46909067 |
| 8 | STK16 | 2.43925708 |
| 9 | MAP4K2 | 2.43736714 |
| 10 | EIF2AK3 | 2.30396470 |
| 11 | TIE1 | 2.29187056 |
| 12 | PINK1 | 2.05079791 |
| 13 | MST4 | 1.94405141 |
| 14 | GRK1 | 1.91373092 |
| 15 | MAP4K1 | 1.78299637 |
| 16 | NUAK1 | 1.78112332 |
| 17 | PIK3CG | 1.73938460 |
| 18 | FES | 1.72740383 |
| 19 | MAP3K9 | 1.67846944 |
| 20 | SRPK1 | 1.60984711 |
| 21 | ITK | 1.50227703 |
| 22 | SCYL2 | 1.49530231 |
| 23 | TAF1 | 1.49007856 |
| 24 | NEK1 | 1.48022961 |
| 25 | TAOK3 | 1.41475340 |
| 26 | VRK1 | 1.37453597 |
| 27 | ADRBK2 | 1.36720702 |
| 28 | PASK | 1.34784254 |
| 29 | OXSR1 | 1.32966274 |
| 30 | TEC | 1.32502931 |
| 31 | EIF2AK1 | 1.24672945 |
| 32 | PBK | 1.21953215 |
| 33 | CDK19 | 1.20844724 |
| 34 | MAP2K7 | 1.16321245 |
| 35 | NME1 | 1.15046046 |
| 36 | ZAK | 1.10110360 |
| 37 | LIMK1 | 1.03870314 |
| 38 | WNK3 | 1.03738740 |
| 39 | DAPK1 | 1.01656051 |
| 40 | BCR | 1.00396978 |
| 41 | CSNK1G3 | 0.99280933 |
| 42 | IRAK4 | 0.98987729 |
| 43 | MAP3K11 | 0.96328383 |
| 44 | TNK2 | 0.94810641 |
| 45 | SYK | 0.93876079 |
| 46 | TESK1 | 0.93194405 |
| 47 | STK39 | 0.91143248 |
| 48 | IKBKE | 0.87227279 |
| 49 | GRK7 | 0.86693209 |
| 50 | PRKCQ | 0.85093215 |
| 51 | MAPKAPK3 | 0.83247757 |
| 52 | TLK1 | 0.81627242 |
| 53 | MYLK | 0.80492175 |
| 54 | MAP2K6 | 0.79717412 |
| 55 | GRK6 | 0.78359962 |
| 56 | CSNK1G1 | 0.76632251 |
| 57 | LYN | 0.76000000 |
| 58 | CSNK1G2 | 0.74970785 |
| 59 | CSNK1A1L | 0.73679359 |
| 60 | CDK8 | 0.73572829 |
| 61 | MATK | 0.73096593 |
| 62 | LCK | 0.71746132 |
| 63 | BMPR1B | 0.69734507 |
| 64 | BTK | 0.65679820 |
| 65 | DYRK2 | 0.65521998 |
| 66 | CSK | 0.65438783 |
| 67 | PIM2 | 0.65186575 |
| 68 | MUSK | 0.64077658 |
| 69 | TSSK6 | 0.61193892 |
| 70 | ACVR1B | 0.59220380 |
| 71 | RPS6KA4 | 0.59059545 |
| 72 | CCNB1 | 0.57347087 |
| 73 | RPS6KA5 | 0.56757364 |
| 74 | INSRR | 0.56462356 |
| 75 | ERBB3 | 0.55587590 |
| 76 | WNK4 | 0.53910778 |
| 77 | AURKA | 0.53517519 |
| 78 | CSF1R | 0.53115778 |
| 79 | TRIM28 | 0.52117055 |
| 80 | GRK5 | 0.50232035 |
| 81 | KIT | 0.50038686 |
| 82 | IKBKB | 0.49596349 |
| 83 | PLK4 | 0.47489102 |
| 84 | PLK2 | 0.46694550 |
| 85 | CSNK2A1 | 0.44229075 |
| 86 | MINK1 | 0.43690196 |
| 87 | MARK1 | 0.42677073 |
| 88 | ADRBK1 | 0.41753749 |
| 89 | IGF1R | 0.39791340 |
| 90 | PIK3CA | 0.39066630 |
| 91 | MAPK13 | 0.38932380 |
| 92 | PLK1 | 0.38445350 |
| 93 | CAMKK2 | 0.37415306 |
| 94 | MAP3K5 | 0.35952224 |
| 95 | TBK1 | 0.35371160 |
| 96 | CSNK2A2 | 0.34321131 |
| 97 | PLK3 | 0.33968874 |
| 98 | HCK | 0.33181083 |
| 99 | ATR | 0.32621353 |
| 100 | AURKB | 0.31313352 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.82710814 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.39806877 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.19660619 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.71512912 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.57319445 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.33417160 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.28783162 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.17888167 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.00782212 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.98195303 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 1.90046432 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.80567384 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.77491338 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.72733242 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.70788561 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.67240876 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.63431908 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.62459531 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.58979348 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.58254379 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.56548312 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51776583 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51364035 |
| 24 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.49458566 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.41957222 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.39982457 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.34695083 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.34413861 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.31955720 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.27573330 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.26690489 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26081573 |
| 33 | DNA replication_Homo sapiens_hsa03030 | 1.24862815 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.21644232 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 1.20901711 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.16254412 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.14447598 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12099934 |
| 39 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.10757176 |
| 40 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.07246099 |
| 41 | Peroxisome_Homo sapiens_hsa04146 | 1.06264161 |
| 42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.05107200 |
| 43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.03140731 |
| 44 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.99743537 |
| 45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.99483520 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98037609 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.97893735 |
| 48 | RNA degradation_Homo sapiens_hsa03018 | 0.97377856 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.95683279 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.95383167 |
| 51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94924637 |
| 52 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88373585 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.88246322 |
| 54 | RNA transport_Homo sapiens_hsa03013 | 0.85895741 |
| 55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.85606404 |
| 56 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.84458566 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.83458393 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.83220950 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.82493363 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80938527 |
| 61 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78652817 |
| 62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.77610788 |
| 63 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.75590852 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74773979 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72930261 |
| 66 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.71968665 |
| 67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.71579561 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.70587733 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69892567 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.69194848 |
| 71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.68670145 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66926372 |
| 73 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.66590952 |
| 74 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.65915758 |
| 75 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65111008 |
| 76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.64050126 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62634579 |
| 78 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60794491 |
| 79 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.60689815 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60460521 |
| 81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.59624370 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56920070 |
| 83 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.56621843 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.55310655 |
| 85 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.51664385 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51302489 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.50085279 |
| 88 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49620432 |
| 89 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.43326953 |
| 90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.43166416 |
| 91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42753919 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.40177640 |
| 93 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.39515358 |
| 94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.39130841 |
| 95 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.37746505 |
| 96 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36485895 |
| 97 | Shigellosis_Homo sapiens_hsa05131 | 0.34096242 |
| 98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33995863 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.33782218 |
| 100 | Sulfur relay system_Homo sapiens_hsa04122 | 0.33203769 |

