

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.64722919 |
| 2 | response to pheromone (GO:0019236) | 5.18662620 |
| 3 | DNA deamination (GO:0045006) | 4.87020010 |
| 4 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.79149245 |
| 5 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.57083064 |
| 6 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.45970879 |
| 7 | regulation of immunoglobulin secretion (GO:0051023) | 4.03009542 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.68292799 |
| 9 | protein polyglutamylation (GO:0018095) | 3.55009078 |
| 10 | protein neddylation (GO:0045116) | 3.51923284 |
| 11 | protein complex biogenesis (GO:0070271) | 3.50691208 |
| 12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.47273533 |
| 13 | regulation of mitochondrial translation (GO:0070129) | 3.41914484 |
| 14 | platelet dense granule organization (GO:0060155) | 3.39782011 |
| 15 | DNA strand renaturation (GO:0000733) | 3.38293876 |
| 16 | regulation of chronic inflammatory response (GO:0002676) | 3.38070707 |
| 17 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38039535 |
| 18 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.34084817 |
| 19 | DNA double-strand break processing (GO:0000729) | 3.34004548 |
| 20 | replication fork processing (GO:0031297) | 3.29944298 |
| 21 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.29538914 |
| 22 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.29538914 |
| 23 | behavioral response to nicotine (GO:0035095) | 3.26838348 |
| 24 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.26734702 |
| 25 | cytochrome complex assembly (GO:0017004) | 3.24553506 |
| 26 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.21782282 |
| 27 | sperm motility (GO:0030317) | 3.18222646 |
| 28 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.18064555 |
| 29 | ATP synthesis coupled proton transport (GO:0015986) | 3.18064555 |
| 30 | ribosomal small subunit assembly (GO:0000028) | 3.15980069 |
| 31 | resolution of meiotic recombination intermediates (GO:0000712) | 3.15435636 |
| 32 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.14975374 |
| 33 | negative regulation of ligase activity (GO:0051352) | 3.14975374 |
| 34 | maturation of SSU-rRNA (GO:0030490) | 3.14821230 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.14042458 |
| 36 | regulation of cilium movement (GO:0003352) | 3.12776548 |
| 37 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.12293732 |
| 38 | rRNA modification (GO:0000154) | 3.11752989 |
| 39 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.10571957 |
| 40 | cytidine metabolic process (GO:0046087) | 3.09416976 |
| 41 | cytidine catabolic process (GO:0006216) | 3.09416976 |
| 42 | cytidine deamination (GO:0009972) | 3.09416976 |
| 43 | L-fucose catabolic process (GO:0042355) | 3.08497244 |
| 44 | fucose catabolic process (GO:0019317) | 3.08497244 |
| 45 | L-fucose metabolic process (GO:0042354) | 3.08497244 |
| 46 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.00177837 |
| 47 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.00177837 |
| 48 | termination of RNA polymerase I transcription (GO:0006363) | 2.98482479 |
| 49 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.98007586 |
| 50 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.98007586 |
| 51 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.98007586 |
| 52 | GTP biosynthetic process (GO:0006183) | 2.97270497 |
| 53 | protein deneddylation (GO:0000338) | 2.94428689 |
| 54 | spliceosomal complex assembly (GO:0000245) | 2.93962778 |
| 55 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.93803341 |
| 56 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.93478168 |
| 57 | negative regulation of telomere maintenance (GO:0032205) | 2.92713449 |
| 58 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.92007578 |
| 59 | sequestering of actin monomers (GO:0042989) | 2.89503353 |
| 60 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.89189725 |
| 61 | nonmotile primary cilium assembly (GO:0035058) | 2.88904647 |
| 62 | cullin deneddylation (GO:0010388) | 2.87127041 |
| 63 | respiratory chain complex IV assembly (GO:0008535) | 2.86377161 |
| 64 | regulation of centriole replication (GO:0046599) | 2.86306933 |
| 65 | histone exchange (GO:0043486) | 2.86271292 |
| 66 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.84866362 |
| 67 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.84674838 |
| 68 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.82651399 |
| 69 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.82651399 |
| 70 | intracellular protein transmembrane import (GO:0044743) | 2.81227809 |
| 71 | positive regulation of prostaglandin secretion (GO:0032308) | 2.81114804 |
| 72 | proteasome assembly (GO:0043248) | 2.79648497 |
| 73 | cellular component biogenesis (GO:0044085) | 2.79299503 |
| 74 | hepatocyte apoptotic process (GO:0097284) | 2.78638723 |
| 75 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.74476720 |
| 76 | positive regulation of organelle assembly (GO:1902117) | 2.73073860 |
| 77 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.72142305 |
| 78 | microtubule depolymerization (GO:0007019) | 2.71403092 |
| 79 | rRNA methylation (GO:0031167) | 2.70266518 |
| 80 | male meiosis I (GO:0007141) | 2.67318391 |
| 81 | ribosome biogenesis (GO:0042254) | 2.64942848 |
| 82 | hydrogen ion transmembrane transport (GO:1902600) | 2.62965024 |
| 83 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.60852447 |
| 84 | electron transport chain (GO:0022900) | 2.60812088 |
| 85 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.59801162 |
| 86 | NADH dehydrogenase complex assembly (GO:0010257) | 2.59801162 |
| 87 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.59801162 |
| 88 | protein localization to peroxisome (GO:0072662) | 2.59604374 |
| 89 | protein targeting to peroxisome (GO:0006625) | 2.59604374 |
| 90 | establishment of protein localization to peroxisome (GO:0072663) | 2.59604374 |
| 91 | ribonucleoprotein complex disassembly (GO:0032988) | 2.59418223 |
| 92 | respiratory electron transport chain (GO:0022904) | 2.58905530 |
| 93 | UTP biosynthetic process (GO:0006228) | 2.58301356 |
| 94 | hypothalamus development (GO:0021854) | 2.56960021 |
| 95 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.55448012 |
| 96 | arginine catabolic process (GO:0006527) | 2.54087292 |
| 97 | somite rostral/caudal axis specification (GO:0032525) | 2.53164672 |
| 98 | positive regulation of activated T cell proliferation (GO:0042104) | 2.52845953 |
| 99 | kinetochore assembly (GO:0051382) | 2.52272801 |
| 100 | organelle disassembly (GO:1903008) | 2.51366013 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.93708849 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.37552856 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43494483 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.41042810 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.10502495 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91434099 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.87250542 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.84683320 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.77808788 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.64642856 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61051434 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.52375341 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.43283857 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.40355012 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.38383253 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.32815583 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.30868881 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.19161202 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.06922922 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.94241562 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.90004849 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.86156314 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.82757815 |
| 24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.73496612 |
| 25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.73473999 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.68849953 |
| 27 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68836605 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.67261240 |
| 29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.66642051 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65134518 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.60347094 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.58344461 |
| 33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.57632439 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.53984242 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.52463325 |
| 36 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.52345355 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.47459141 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.46878045 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.41855314 |
| 40 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.41002694 |
| 41 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.39646978 |
| 42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.39351712 |
| 43 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.38237785 |
| 44 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.37230059 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34546869 |
| 46 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.32367659 |
| 47 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.29828076 |
| 48 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.29155718 |
| 49 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.26947683 |
| 50 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.26471132 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25513119 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25513119 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25477217 |
| 54 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.24872090 |
| 55 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.24505855 |
| 56 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.21924972 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20477385 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.17426244 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.16325110 |
| 60 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.15292199 |
| 61 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.15028625 |
| 62 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.12359292 |
| 63 | ERA_21632823_ChIP-Seq_H3396_Human | 1.12225027 |
| 64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.12026077 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11039976 |
| 66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11039976 |
| 67 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.07968960 |
| 68 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06867737 |
| 69 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.06015163 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.05567003 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.05567003 |
| 72 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.05357263 |
| 73 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.05309520 |
| 74 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.05205638 |
| 75 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04130183 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04079660 |
| 77 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03384746 |
| 78 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02573603 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.02341055 |
| 80 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01697627 |
| 81 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01650571 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.99753755 |
| 83 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.98365210 |
| 84 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.98324916 |
| 85 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.97022765 |
| 86 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96905093 |
| 87 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.96439228 |
| 88 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.96357405 |
| 89 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.96338329 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.96112878 |
| 91 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.95200776 |
| 92 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.95019452 |
| 93 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.93072510 |
| 94 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.92585784 |
| 95 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91950854 |
| 96 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88427412 |
| 97 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.86507459 |
| 98 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.85899890 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84146712 |
| 100 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.83940095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001529_abnormal_vocalization | 3.44585196 |
| 2 | MP0008789_abnormal_olfactory_epithelium | 2.89372301 |
| 3 | MP0003878_abnormal_ear_physiology | 2.74946763 |
| 4 | MP0005377_hearing/vestibular/ear_phenot | 2.74946763 |
| 5 | MP0006292_abnormal_olfactory_placode | 2.67981688 |
| 6 | MP0003718_maternal_effect | 2.47000953 |
| 7 | MP0005410_abnormal_fertilization | 2.46034776 |
| 8 | MP0008872_abnormal_physiological_respon | 2.38976146 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.31890563 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.28497425 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.25429289 |
| 12 | MP0000566_synostosis | 2.21582004 |
| 13 | MP0005394_taste/olfaction_phenotype | 2.21170265 |
| 14 | MP0005499_abnormal_olfactory_system | 2.21170265 |
| 15 | MP0002736_abnormal_nociception_after | 2.07149231 |
| 16 | MP0008875_abnormal_xenobiotic_pharmacok | 2.04322078 |
| 17 | MP0001348_abnormal_lacrimal_gland | 1.96127967 |
| 18 | MP0004142_abnormal_muscle_tone | 1.94816204 |
| 19 | MP0001968_abnormal_touch/_nociception | 1.86721879 |
| 20 | MP0003646_muscle_fatigue | 1.81122201 |
| 21 | MP0008058_abnormal_DNA_repair | 1.80064991 |
| 22 | MP0004147_increased_porphyrin_level | 1.74621671 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.74397859 |
| 24 | MP0003693_abnormal_embryo_hatching | 1.74330408 |
| 25 | MP0001873_stomach_inflammation | 1.73719857 |
| 26 | MP0002163_abnormal_gland_morphology | 1.70911003 |
| 27 | MP0002102_abnormal_ear_morphology | 1.66521718 |
| 28 | MP0002138_abnormal_hepatobiliary_system | 1.66370492 |
| 29 | MP0003880_abnormal_central_pattern | 1.65583199 |
| 30 | MP0003011_delayed_dark_adaptation | 1.61093637 |
| 31 | MP0003786_premature_aging | 1.58088502 |
| 32 | MP0001984_abnormal_olfaction | 1.57020104 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.53262976 |
| 34 | MP0006054_spinal_hemorrhage | 1.46870123 |
| 35 | MP0004742_abnormal_vestibular_system | 1.43417591 |
| 36 | MP0001293_anophthalmia | 1.43287530 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.42960400 |
| 38 | MP0005253_abnormal_eye_physiology | 1.39985020 |
| 39 | MP0006276_abnormal_autonomic_nervous | 1.38273104 |
| 40 | MP0001919_abnormal_reproductive_system | 1.33622019 |
| 41 | MP0000015_abnormal_ear_pigmentation | 1.31696451 |
| 42 | MP0002653_abnormal_ependyma_morphology | 1.31408168 |
| 43 | MP0002272_abnormal_nervous_system | 1.30759937 |
| 44 | MP0010094_abnormal_chromosome_stability | 1.30172323 |
| 45 | MP0004782_abnormal_surfactant_physiolog | 1.29674073 |
| 46 | MP0002210_abnormal_sex_determination | 1.28034745 |
| 47 | MP0001835_abnormal_antigen_presentation | 1.24108686 |
| 48 | MP0003698_abnormal_male_reproductive | 1.24005410 |
| 49 | MP0001929_abnormal_gametogenesis | 1.18994290 |
| 50 | MP0002234_abnormal_pharynx_morphology | 1.18866274 |
| 51 | MP0003122_maternal_imprinting | 1.13530430 |
| 52 | MP0002822_catalepsy | 1.09975306 |
| 53 | MP0009745_abnormal_behavioral_response | 1.07959335 |
| 54 | MP0001188_hyperpigmentation | 1.07480098 |
| 55 | MP0005379_endocrine/exocrine_gland_phen | 1.05958968 |
| 56 | MP0005646_abnormal_pituitary_gland | 1.05099165 |
| 57 | MP0001145_abnormal_male_reproductive | 1.04494327 |
| 58 | MP0001986_abnormal_taste_sensitivity | 1.04221805 |
| 59 | MP0000569_abnormal_digit_pigmentation | 1.03876802 |
| 60 | MP0004885_abnormal_endolymph | 1.03776775 |
| 61 | MP0003121_genomic_imprinting | 1.02751089 |
| 62 | MP0009053_abnormal_anal_canal | 1.02579408 |
| 63 | MP0002184_abnormal_innervation | 1.01498908 |
| 64 | MP0002095_abnormal_skin_pigmentation | 1.01299955 |
| 65 | MP0000653_abnormal_sex_gland | 1.00892242 |
| 66 | MP0004043_abnormal_pH_regulation | 1.00878432 |
| 67 | MP0000631_abnormal_neuroendocrine_gland | 0.99769722 |
| 68 | MP0001501_abnormal_sleep_pattern | 0.99649190 |
| 69 | MP0005395_other_phenotype | 0.99614875 |
| 70 | MP0005389_reproductive_system_phenotype | 0.99129742 |
| 71 | MP0005310_abnormal_salivary_gland | 0.98312356 |
| 72 | MP0006035_abnormal_mitochondrial_morpho | 0.97590536 |
| 73 | MP0008932_abnormal_embryonic_tissue | 0.96740724 |
| 74 | MP0000049_abnormal_middle_ear | 0.94270451 |
| 75 | MP0005075_abnormal_melanosome_morpholog | 0.93065236 |
| 76 | MP0005408_hypopigmentation | 0.92899482 |
| 77 | MP0004957_abnormal_blastocyst_morpholog | 0.92737311 |
| 78 | MP0000427_abnormal_hair_cycle | 0.92712152 |
| 79 | MP0003787_abnormal_imprinting | 0.92640684 |
| 80 | MP0001853_heart_inflammation | 0.91156513 |
| 81 | MP0002557_abnormal_social/conspecific_i | 0.90853389 |
| 82 | MP0003567_abnormal_fetal_cardiomyocyte | 0.88845283 |
| 83 | MP0002938_white_spotting | 0.88268474 |
| 84 | MP0005167_abnormal_blood-brain_barrier | 0.84635635 |
| 85 | MP0005083_abnormal_biliary_tract | 0.84239512 |
| 86 | MP0001119_abnormal_female_reproductive | 0.83783927 |
| 87 | MP0001905_abnormal_dopamine_level | 0.83140584 |
| 88 | MP0005670_abnormal_white_adipose | 0.82838987 |
| 89 | MP0001486_abnormal_startle_reflex | 0.81554636 |
| 90 | MP0003866_abnormal_defecation | 0.80985029 |
| 91 | MP0005387_immune_system_phenotype | 0.78154355 |
| 92 | MP0001790_abnormal_immune_system | 0.78154355 |
| 93 | MP0008007_abnormal_cellular_replicative | 0.77045281 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.76865087 |
| 95 | MP0002067_abnormal_sensory_capabilities | 0.76038464 |
| 96 | MP0009785_altered_susceptibility_to | 0.75000371 |
| 97 | MP0005195_abnormal_posterior_eye | 0.74325499 |
| 98 | MP0005636_abnormal_mineral_homeostasis | 0.72077197 |
| 99 | MP0001765_abnormal_ion_homeostasis | 0.71223065 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.71093063 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.46492064 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 4.05887732 |
| 3 | Renal Fanconi syndrome (HP:0001994) | 3.91102854 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.90790353 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.61876169 |
| 6 | Increased CSF lactate (HP:0002490) | 3.50192970 |
| 7 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.27237432 |
| 8 | Pancreatic fibrosis (HP:0100732) | 3.25279483 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.23775973 |
| 10 | Abnormality of the labia minora (HP:0012880) | 3.22412944 |
| 11 | Chronic hepatic failure (HP:0100626) | 3.17403920 |
| 12 | Acute encephalopathy (HP:0006846) | 3.12686883 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.05857528 |
| 14 | Pendular nystagmus (HP:0012043) | 3.02004749 |
| 15 | Type II lissencephaly (HP:0007260) | 2.99707171 |
| 16 | Pancreatic cysts (HP:0001737) | 2.91176026 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 2.88224410 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 2.88224410 |
| 19 | Nephronophthisis (HP:0000090) | 2.83171864 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 2.82459474 |
| 21 | Progressive macrocephaly (HP:0004481) | 2.81048013 |
| 22 | True hermaphroditism (HP:0010459) | 2.79614194 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.77302078 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.75088305 |
| 25 | Hepatic necrosis (HP:0002605) | 2.67812261 |
| 26 | Hyperglycinemia (HP:0002154) | 2.62341832 |
| 27 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.62178693 |
| 28 | Exertional dyspnea (HP:0002875) | 2.57914313 |
| 29 | Type 2 muscle fiber atrophy (HP:0003554) | 2.57404669 |
| 30 | Increased serum lactate (HP:0002151) | 2.53644409 |
| 31 | Abnormality of the aortic arch (HP:0012303) | 2.50262482 |
| 32 | Methylmalonic aciduria (HP:0012120) | 2.49244920 |
| 33 | Medial flaring of the eyebrow (HP:0010747) | 2.46456318 |
| 34 | Rib fusion (HP:0000902) | 2.43171774 |
| 35 | Abnormality of renal resorption (HP:0011038) | 2.38653806 |
| 36 | Abnormal biliary tract physiology (HP:0012439) | 2.36639549 |
| 37 | Bile duct proliferation (HP:0001408) | 2.36639549 |
| 38 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.35888364 |
| 39 | Methylmalonic acidemia (HP:0002912) | 2.34429111 |
| 40 | Severe visual impairment (HP:0001141) | 2.33882089 |
| 41 | IgG deficiency (HP:0004315) | 2.33809412 |
| 42 | Respiratory difficulties (HP:0002880) | 2.33192779 |
| 43 | Gait imbalance (HP:0002141) | 2.29076991 |
| 44 | Genetic anticipation (HP:0003743) | 2.25512778 |
| 45 | Abolished electroretinogram (ERG) (HP:0000550) | 2.25204001 |
| 46 | Muscle fiber atrophy (HP:0100295) | 2.25012369 |
| 47 | Increased muscle lipid content (HP:0009058) | 2.24795732 |
| 48 | Cerebral edema (HP:0002181) | 2.22752366 |
| 49 | Abnormal lung lobation (HP:0002101) | 2.21636740 |
| 50 | Tubulointerstitial nephritis (HP:0001970) | 2.21335828 |
| 51 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.19598497 |
| 52 | Congenital primary aphakia (HP:0007707) | 2.17968295 |
| 53 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.17430225 |
| 54 | Abnormality of the renal medulla (HP:0100957) | 2.16857085 |
| 55 | Optic disc pallor (HP:0000543) | 2.14837874 |
| 56 | Abnormality of the ileum (HP:0001549) | 2.13985955 |
| 57 | Lissencephaly (HP:0001339) | 2.10450028 |
| 58 | Cerebellar dysplasia (HP:0007033) | 2.09682088 |
| 59 | Colon cancer (HP:0003003) | 2.08991881 |
| 60 | Tubular atrophy (HP:0000092) | 2.08758327 |
| 61 | Ectopic kidney (HP:0000086) | 2.08222560 |
| 62 | Meckel diverticulum (HP:0002245) | 2.03192487 |
| 63 | Lactic acidosis (HP:0003128) | 1.99682013 |
| 64 | Postaxial foot polydactyly (HP:0001830) | 1.99279194 |
| 65 | Oligodactyly (HP:0012165) | 1.99044733 |
| 66 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.97481645 |
| 67 | Nephrogenic diabetes insipidus (HP:0009806) | 1.96875894 |
| 68 | Retinal dysplasia (HP:0007973) | 1.92799149 |
| 69 | Hyperphosphaturia (HP:0003109) | 1.92584521 |
| 70 | Pancytopenia (HP:0001876) | 1.92479470 |
| 71 | 3-Methylglutaconic aciduria (HP:0003535) | 1.88924598 |
| 72 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88221670 |
| 73 | Albinism (HP:0001022) | 1.86526430 |
| 74 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.86117476 |
| 75 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.86117476 |
| 76 | Hypoalbuminemia (HP:0003073) | 1.83751417 |
| 77 | Abnormal albumin level (HP:0012116) | 1.83751417 |
| 78 | Microvesicular hepatic steatosis (HP:0001414) | 1.82055264 |
| 79 | Agitation (HP:0000713) | 1.81417248 |
| 80 | Progressive cerebellar ataxia (HP:0002073) | 1.81186366 |
| 81 | Emotional lability (HP:0000712) | 1.77672255 |
| 82 | Hypoplasia of the uterus (HP:0000013) | 1.77091280 |
| 83 | Asplenia (HP:0001746) | 1.76207185 |
| 84 | Carpal bone hypoplasia (HP:0001498) | 1.75628091 |
| 85 | Cystic liver disease (HP:0006706) | 1.75396901 |
| 86 | Supernumerary spleens (HP:0009799) | 1.74508710 |
| 87 | Thyroid-stimulating hormone excess (HP:0002925) | 1.74136497 |
| 88 | Brushfield spots (HP:0001088) | 1.72225202 |
| 89 | Abnormality of the pons (HP:0007361) | 1.71499194 |
| 90 | Horseshoe kidney (HP:0000085) | 1.71337785 |
| 91 | Exercise intolerance (HP:0003546) | 1.71325394 |
| 92 | Absent thumb (HP:0009777) | 1.71031332 |
| 93 | Intestinal atresia (HP:0011100) | 1.70073883 |
| 94 | Failure to thrive in infancy (HP:0001531) | 1.69022310 |
| 95 | Narrow forehead (HP:0000341) | 1.68826551 |
| 96 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.68078629 |
| 97 | Lethargy (HP:0001254) | 1.68014164 |
| 98 | Severe combined immunodeficiency (HP:0004430) | 1.65713671 |
| 99 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.65348689 |
| 100 | Absent/shortened dynein arms (HP:0200106) | 1.65348689 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK1 | 3.57355100 |
| 2 | PLK4 | 3.53759121 |
| 3 | EIF2AK3 | 3.31423755 |
| 4 | VRK2 | 3.15401110 |
| 5 | EIF2AK1 | 2.94457245 |
| 6 | MAP4K2 | 2.88784043 |
| 7 | TXK | 2.59780406 |
| 8 | SRPK1 | 2.39828738 |
| 9 | ADRBK2 | 2.37328112 |
| 10 | TSSK6 | 2.19648197 |
| 11 | WNK4 | 2.18580654 |
| 12 | PBK | 2.12283427 |
| 13 | TRIM28 | 1.89229947 |
| 14 | BCKDK | 1.85911274 |
| 15 | DYRK2 | 1.78878715 |
| 16 | BUB1 | 1.77470514 |
| 17 | NUAK1 | 1.71418485 |
| 18 | VRK1 | 1.68602384 |
| 19 | NME1 | 1.68006048 |
| 20 | MST4 | 1.60210682 |
| 21 | EPHB2 | 1.59087525 |
| 22 | BCR | 1.57073678 |
| 23 | PLK3 | 1.51446381 |
| 24 | WNK3 | 1.48921130 |
| 25 | TAOK3 | 1.48088280 |
| 26 | PAK3 | 1.46900315 |
| 27 | MKNK2 | 1.46030351 |
| 28 | GRK1 | 1.45328320 |
| 29 | CSNK1G3 | 1.44659668 |
| 30 | PLK2 | 1.34696348 |
| 31 | PRKD3 | 1.30785729 |
| 32 | CSNK1G2 | 1.23308200 |
| 33 | TAF1 | 1.22957700 |
| 34 | WEE1 | 1.22905455 |
| 35 | SIK3 | 1.19566914 |
| 36 | LIMK1 | 1.13930322 |
| 37 | CSNK1A1L | 1.09022489 |
| 38 | STK39 | 1.08860844 |
| 39 | PINK1 | 1.07200706 |
| 40 | MINK1 | 1.05859167 |
| 41 | AKT3 | 1.02868188 |
| 42 | NEK1 | 1.02121882 |
| 43 | CSNK1G1 | 1.00476691 |
| 44 | ERBB3 | 0.98445433 |
| 45 | MAP2K7 | 0.96532919 |
| 46 | TLK1 | 0.94840518 |
| 47 | KDR | 0.92561604 |
| 48 | MAPK13 | 0.92445056 |
| 49 | MAP3K4 | 0.91624424 |
| 50 | CDK8 | 0.90584703 |
| 51 | MKNK1 | 0.87847191 |
| 52 | PRKCG | 0.87728477 |
| 53 | INSRR | 0.85970275 |
| 54 | MAP3K9 | 0.85334562 |
| 55 | TESK2 | 0.83974338 |
| 56 | OXSR1 | 0.79419405 |
| 57 | NEK2 | 0.77294553 |
| 58 | WNK1 | 0.75829177 |
| 59 | PAK6 | 0.72006883 |
| 60 | PLK1 | 0.67975225 |
| 61 | FRK | 0.66996088 |
| 62 | EIF2AK2 | 0.66712343 |
| 63 | AURKB | 0.63514276 |
| 64 | PDK2 | 0.57796219 |
| 65 | KSR1 | 0.54478058 |
| 66 | ZAK | 0.51661316 |
| 67 | CSNK2A2 | 0.50915820 |
| 68 | PRKCQ | 0.50841088 |
| 69 | RAF1 | 0.50721383 |
| 70 | CSNK1A1 | 0.50216635 |
| 71 | ATR | 0.50017913 |
| 72 | BRSK2 | 0.49962842 |
| 73 | IKBKB | 0.49892833 |
| 74 | STK4 | 0.48853876 |
| 75 | CAMKK2 | 0.47787909 |
| 76 | CSNK2A1 | 0.47270900 |
| 77 | DAPK1 | 0.45220761 |
| 78 | MARK1 | 0.44937596 |
| 79 | BRAF | 0.42947097 |
| 80 | PHKG2 | 0.41244820 |
| 81 | PHKG1 | 0.41244820 |
| 82 | CHEK2 | 0.40921679 |
| 83 | TIE1 | 0.39420887 |
| 84 | CSNK1E | 0.37728228 |
| 85 | CAMK2A | 0.35570804 |
| 86 | STK16 | 0.34641809 |
| 87 | AURKA | 0.33657225 |
| 88 | CDK14 | 0.33188637 |
| 89 | IKBKE | 0.29515297 |
| 90 | TYRO3 | 0.27845293 |
| 91 | PRKACA | 0.27497449 |
| 92 | STK38 | 0.27451286 |
| 93 | PRKCB | 0.25259857 |
| 94 | TTK | 0.24756143 |
| 95 | PRKCD | 0.22729250 |
| 96 | MAPKAPK3 | 0.21378595 |
| 97 | ATM | 0.20821926 |
| 98 | DYRK3 | 0.19965903 |
| 99 | IRAK4 | 0.19770981 |
| 100 | MAP3K8 | 0.17333961 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.82315028 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.39268409 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.26953083 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.88796241 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.88787263 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.86743839 |
| 7 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.46236679 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.37696703 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.26910407 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.19166348 |
| 11 | RNA transport_Homo sapiens_hsa03013 | 2.18274651 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.10642831 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.01987645 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.98997627 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.94371627 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.94068453 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.90613013 |
| 18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.81646967 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.74331599 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.74158833 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.67093409 |
| 22 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.59954067 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.57905385 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.54983984 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.54140990 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.53421995 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.50375458 |
| 28 | Spliceosome_Homo sapiens_hsa03040 | 1.43044910 |
| 29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.38116340 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.36565783 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.36246424 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.28209140 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.24524812 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.23367249 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.19898337 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.19155764 |
| 37 | Asthma_Homo sapiens_hsa05310 | 1.14690710 |
| 38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.14306675 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 1.13519941 |
| 40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.08222965 |
| 41 | Peroxisome_Homo sapiens_hsa04146 | 1.05794009 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01321829 |
| 43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.98039247 |
| 44 | Nicotine addiction_Homo sapiens_hsa05033 | 0.98007897 |
| 45 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.96264207 |
| 46 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.95123051 |
| 47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.94318206 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.93565147 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92663598 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.89583782 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.83790668 |
| 52 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.82628450 |
| 53 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.80882235 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.78403321 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77486709 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77065908 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.75579028 |
| 58 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.72386213 |
| 59 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.71893785 |
| 60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.70623781 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67223917 |
| 62 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.65046019 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.60188540 |
| 64 | GABAergic synapse_Homo sapiens_hsa04727 | 0.58887255 |
| 65 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.57628708 |
| 66 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.57019435 |
| 67 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.56537832 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.56155926 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.54229998 |
| 70 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54189336 |
| 71 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53243985 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.52384018 |
| 73 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.52113596 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50690641 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50551576 |
| 76 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50540433 |
| 77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.49083036 |
| 78 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.47978873 |
| 79 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.47970662 |
| 80 | Taste transduction_Homo sapiens_hsa04742 | 0.44193816 |
| 81 | Morphine addiction_Homo sapiens_hsa05032 | 0.41564365 |
| 82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37623814 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36565644 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35541942 |
| 85 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.34029345 |
| 86 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33761575 |
| 87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28404501 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.28302739 |
| 89 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.28152745 |
| 90 | Measles_Homo sapiens_hsa05162 | 0.27636253 |
| 91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.25624401 |
| 92 | Cell cycle_Homo sapiens_hsa04110 | 0.25563504 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.25051119 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.24679861 |
| 95 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.24400611 |
| 96 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.22435545 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.22370696 |
| 98 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21851508 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.20708810 |
| 100 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.19793611 |

