Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.85997892 |
2 | DNA deamination (GO:0045006) | 5.73603489 |
3 | viral transcription (GO:0019083) | 5.55355978 |
4 | translational termination (GO:0006415) | 5.40058232 |
5 | nuclear pore complex assembly (GO:0051292) | 5.33989699 |
6 | telomere maintenance via semi-conservative replication (GO:0032201) | 5.16505489 |
7 | mitotic chromosome condensation (GO:0007076) | 5.13307784 |
8 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.96232563 |
9 | DNA replication initiation (GO:0006270) | 4.88751565 |
10 | maturation of SSU-rRNA (GO:0030490) | 4.83309202 |
11 | ribosomal small subunit biogenesis (GO:0042274) | 4.82821047 |
12 | translational elongation (GO:0006414) | 4.74819799 |
13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.73223719 |
14 | DNA strand elongation (GO:0022616) | 4.73120861 |
15 | regulation of translational fidelity (GO:0006450) | 4.64540339 |
16 | cotranslational protein targeting to membrane (GO:0006613) | 4.60456025 |
17 | protein targeting to ER (GO:0045047) | 4.59368154 |
18 | nuclear pore organization (GO:0006999) | 4.52720558 |
19 | telomere maintenance via recombination (GO:0000722) | 4.38749904 |
20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.36404814 |
21 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.35419895 |
22 | protein localization to endoplasmic reticulum (GO:0070972) | 4.33484936 |
23 | translational initiation (GO:0006413) | 4.30672937 |
24 | mitotic sister chromatid segregation (GO:0000070) | 4.22596738 |
25 | viral life cycle (GO:0019058) | 4.15460050 |
26 | cellular protein complex disassembly (GO:0043624) | 4.09572207 |
27 | chromosome condensation (GO:0030261) | 4.00431968 |
28 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.99124560 |
29 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.98380345 |
30 | pore complex assembly (GO:0046931) | 3.95723504 |
31 | mitotic recombination (GO:0006312) | 3.94283745 |
32 | sister chromatid segregation (GO:0000819) | 3.90434113 |
33 | ribosomal large subunit biogenesis (GO:0042273) | 3.86694504 |
34 | heterochromatin organization (GO:0070828) | 3.85870198 |
35 | telomere maintenance via telomere lengthening (GO:0010833) | 3.80382065 |
36 | mitotic metaphase plate congression (GO:0007080) | 3.79281059 |
37 | protein complex disassembly (GO:0043241) | 3.76207428 |
38 | proline biosynthetic process (GO:0006561) | 3.75375314 |
39 | DNA unwinding involved in DNA replication (GO:0006268) | 3.74602646 |
40 | establishment of viral latency (GO:0019043) | 3.73449802 |
41 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.68442258 |
42 | DNA topological change (GO:0006265) | 3.67151146 |
43 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.66962522 |
44 | COPI coating of Golgi vesicle (GO:0048205) | 3.64416755 |
45 | Golgi transport vesicle coating (GO:0048200) | 3.64416755 |
46 | protein complex localization (GO:0031503) | 3.57651219 |
47 | mitotic sister chromatid cohesion (GO:0007064) | 3.53425023 |
48 | macromolecular complex disassembly (GO:0032984) | 3.52944810 |
49 | DNA packaging (GO:0006323) | 3.52074218 |
50 | DNA duplex unwinding (GO:0032508) | 3.51142101 |
51 | pseudouridine synthesis (GO:0001522) | 3.49590146 |
52 | histone arginine methylation (GO:0034969) | 3.46605470 |
53 | nucleosome disassembly (GO:0006337) | 3.44755549 |
54 | protein-DNA complex disassembly (GO:0032986) | 3.44755549 |
55 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.43038293 |
56 | peptidyl-arginine methylation (GO:0018216) | 3.41079851 |
57 | peptidyl-arginine N-methylation (GO:0035246) | 3.41079851 |
58 | nuclear envelope disassembly (GO:0051081) | 3.40239077 |
59 | membrane disassembly (GO:0030397) | 3.40239077 |
60 | DNA conformation change (GO:0071103) | 3.38875921 |
61 | formation of translation preinitiation complex (GO:0001731) | 3.38005379 |
62 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.34909643 |
63 | DNA geometric change (GO:0032392) | 3.34002648 |
64 | rRNA processing (GO:0006364) | 3.32130542 |
65 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.31285837 |
66 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.30653664 |
67 | mRNA catabolic process (GO:0006402) | 3.27771018 |
68 | DNA replication checkpoint (GO:0000076) | 3.24760875 |
69 | RNA catabolic process (GO:0006401) | 3.23436083 |
70 | translation (GO:0006412) | 3.22295214 |
71 | rRNA metabolic process (GO:0016072) | 3.21739784 |
72 | regulation of translational termination (GO:0006449) | 3.21315799 |
73 | ribosome biogenesis (GO:0042254) | 3.20790186 |
74 | negative regulation of mRNA metabolic process (GO:1903312) | 3.19386433 |
75 | ribosome assembly (GO:0042255) | 3.15932534 |
76 | regulation of RNA export from nucleus (GO:0046831) | 3.15140074 |
77 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.08972475 |
78 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.07589861 |
79 | negative regulation of RNA splicing (GO:0033119) | 3.06709022 |
80 | positive regulation of chromosome segregation (GO:0051984) | 3.06233061 |
81 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.04743561 |
82 | metaphase plate congression (GO:0051310) | 3.04597188 |
83 | CENP-A containing nucleosome assembly (GO:0034080) | 3.03462752 |
84 | protein maturation by protein folding (GO:0022417) | 3.01969458 |
85 | regulation of mitotic spindle organization (GO:0060236) | 3.01346243 |
86 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.00993140 |
87 | chromatin remodeling at centromere (GO:0031055) | 2.99722487 |
88 | cellular protein complex localization (GO:0034629) | 2.99556525 |
89 | tRNA methylation (GO:0030488) | 2.98620386 |
90 | proteasome assembly (GO:0043248) | 2.94913087 |
91 | spliceosomal snRNP assembly (GO:0000387) | 2.94444601 |
92 | nucleobase biosynthetic process (GO:0046112) | 2.93924681 |
93 | ATP-dependent chromatin remodeling (GO:0043044) | 2.93375844 |
94 | protein targeting to membrane (GO:0006612) | 2.91862777 |
95 | translesion synthesis (GO:0019985) | 2.90249051 |
96 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.89807678 |
97 | platelet dense granule organization (GO:0060155) | 2.88138934 |
98 | protein export from nucleus (GO:0006611) | 2.87871041 |
99 | regulation of centriole replication (GO:0046599) | 2.87405111 |
100 | chromatin assembly or disassembly (GO:0006333) | 2.86132289 |
101 | rRNA transcription (GO:0009303) | 2.84736652 |
102 | tRNA aminoacylation for protein translation (GO:0006418) | 2.83637620 |
103 | nuclear envelope organization (GO:0006998) | 2.83294482 |
104 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.82973564 |
105 | lymphoid progenitor cell differentiation (GO:0002320) | 2.82843208 |
106 | mRNA stabilization (GO:0048255) | 2.82103052 |
107 | RNA stabilization (GO:0043489) | 2.82103052 |
108 | DNA replication-independent nucleosome organization (GO:0034724) | 2.81731706 |
109 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.81731706 |
110 | regulation of spindle organization (GO:0090224) | 2.81595920 |
111 | pentose-phosphate shunt (GO:0006098) | 2.81475518 |
112 | chromatin assembly (GO:0031497) | 2.80403523 |
113 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.80026792 |
114 | L-serine metabolic process (GO:0006563) | 2.79871503 |
115 | intra-S DNA damage checkpoint (GO:0031573) | 2.79301074 |
116 | DNA ligation (GO:0006266) | 2.78526624 |
117 | telomere maintenance (GO:0000723) | 2.77172496 |
118 | telomere organization (GO:0032200) | 2.76950420 |
119 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.76264856 |
120 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.76264856 |
121 | regulation of translational elongation (GO:0006448) | 2.75595429 |
122 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.74975156 |
123 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.74750417 |
124 | non-recombinational repair (GO:0000726) | 2.74750417 |
125 | establishment of chromosome localization (GO:0051303) | 2.74206777 |
126 | cellular component biogenesis (GO:0044085) | 2.74200531 |
127 | IMP biosynthetic process (GO:0006188) | 2.73746469 |
128 | establishment of integrated proviral latency (GO:0075713) | 2.72985591 |
129 | amino acid activation (GO:0043038) | 2.72877584 |
130 | tRNA aminoacylation (GO:0043039) | 2.72877584 |
131 | definitive hemopoiesis (GO:0060216) | 2.72597647 |
132 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.72461293 |
133 | regulation of sister chromatid cohesion (GO:0007063) | 2.71485931 |
134 | chromosome segregation (GO:0007059) | 2.70928437 |
135 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.70752151 |
136 | regulation of chromosome segregation (GO:0051983) | 2.70377796 |
137 | termination of RNA polymerase II transcription (GO:0006369) | 2.70261994 |
138 | protein localization to chromosome, centromeric region (GO:0071459) | 2.69460051 |
139 | protein retention in ER lumen (GO:0006621) | 2.69090199 |
140 | protein localization to kinetochore (GO:0034501) | 2.68152162 |
141 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.66505734 |
142 | GDP-mannose metabolic process (GO:0019673) | 2.61236827 |
143 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.61055815 |
144 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.60201723 |
145 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.60201723 |
146 | isotype switching (GO:0045190) | 2.60201723 |
147 | IMP metabolic process (GO:0046040) | 2.59700204 |
148 | termination of RNA polymerase III transcription (GO:0006386) | 2.59369403 |
149 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.59369403 |
150 | tRNA modification (GO:0006400) | 2.59107452 |
151 | ncRNA processing (GO:0034470) | 2.58731005 |
152 | respiratory chain complex IV assembly (GO:0008535) | 2.58304574 |
153 | histone exchange (GO:0043486) | 2.57217503 |
154 | viral mRNA export from host cell nucleus (GO:0046784) | 2.54703022 |
155 | purine nucleobase biosynthetic process (GO:0009113) | 2.53955502 |
156 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.53391051 |
157 | negative regulation of mRNA processing (GO:0050686) | 2.51875270 |
158 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.51037675 |
159 | mRNA splicing, via spliceosome (GO:0000398) | 2.51037675 |
160 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.50777704 |
161 | mitochondrial DNA replication (GO:0006264) | 2.49611336 |
162 | RNA splicing, via transesterification reactions (GO:0000375) | 2.49517440 |
163 | response to interferon-beta (GO:0035456) | 2.49503448 |
164 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.47915805 |
165 | histone mRNA metabolic process (GO:0008334) | 2.47373112 |
166 | ncRNA metabolic process (GO:0034660) | 2.47250605 |
167 | mitotic nuclear envelope disassembly (GO:0007077) | 2.47213825 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.48424130 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.22222407 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.95378523 |
4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.16917208 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.00347105 |
6 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.90285728 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.71280675 |
8 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.69765617 |
9 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.66814295 |
10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.65981998 |
11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.64104987 |
12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.63372882 |
13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.59791193 |
14 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.58558090 |
15 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.55729207 |
16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.52998803 |
17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.51132984 |
18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.47205543 |
19 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.43335846 |
20 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.37151668 |
21 | * MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.23285814 |
22 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.22695238 |
23 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.22447243 |
24 | MYC_22102868_ChIP-Seq_BL_Human | 2.20748751 |
25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.11707554 |
26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.09517324 |
27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07341626 |
28 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.06543230 |
29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.98960522 |
30 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.93653597 |
31 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.87850939 |
32 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.86350369 |
33 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.84236742 |
34 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.82857930 |
35 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.82708022 |
36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81617685 |
37 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.81585101 |
38 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.81550214 |
39 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.79735507 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.77993414 |
41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.77924033 |
42 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.77853393 |
43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.76617991 |
44 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.76116360 |
45 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.75629854 |
46 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.74964708 |
47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.66614804 |
48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.66587186 |
49 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.65598903 |
50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.63840979 |
51 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.63086855 |
52 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.61360415 |
53 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.61306633 |
54 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.59060840 |
55 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.58512957 |
56 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.57423623 |
57 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.54315159 |
58 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.52276686 |
59 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.51615308 |
60 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.50279963 |
61 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.49224512 |
62 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.48135039 |
63 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.47598009 |
64 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.46301058 |
65 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.44902036 |
66 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.42268333 |
67 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.41452914 |
68 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.40129011 |
69 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.39505822 |
70 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.38266494 |
71 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.34132727 |
72 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.30782312 |
73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.26159581 |
74 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.26134708 |
75 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.25063812 |
76 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.21829767 |
77 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.21479501 |
78 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.21424922 |
79 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.19062468 |
80 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.18163413 |
81 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.16895964 |
82 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.16801175 |
83 | MYB_26560356_Chip-Seq_TH2_Human | 1.15353610 |
84 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.14900376 |
85 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.13859454 |
86 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12688983 |
87 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.12684742 |
88 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12659007 |
89 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.12361083 |
90 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.12259313 |
91 | MAF_26560356_Chip-Seq_TH1_Human | 1.12232357 |
92 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.11702370 |
93 | MYB_26560356_Chip-Seq_TH1_Human | 1.11040507 |
94 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.09952042 |
95 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09754862 |
96 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09305990 |
97 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.07557582 |
98 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.06367987 |
99 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05923394 |
100 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.05788424 |
101 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.05658556 |
102 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05163334 |
103 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.04633003 |
104 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04525396 |
105 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.03851753 |
106 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.03238789 |
107 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.03228213 |
108 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.03209221 |
109 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.03117933 |
110 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.02919207 |
111 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02733764 |
112 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.02662470 |
113 | UTX_26944678_Chip-Seq_JUKART_Human | 1.02631124 |
114 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.02167807 |
115 | ATF3_27146783_Chip-Seq_COLON_Human | 1.01869870 |
116 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.00992052 |
117 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.00204467 |
118 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.99711538 |
119 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.99065772 |
120 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.97847354 |
121 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.97546390 |
122 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.97310616 |
123 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96127158 |
124 | * TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.91634896 |
125 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91609030 |
126 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.90591865 |
127 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.90141651 |
128 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.90084854 |
129 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.90062696 |
130 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.89553660 |
131 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88579213 |
132 | MAF_26560356_Chip-Seq_TH2_Human | 0.87607986 |
133 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.87142665 |
134 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.87039504 |
135 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.86859120 |
136 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.85960354 |
137 | GATA1_22025678_ChIP-Seq_K562_Human | 0.85552780 |
138 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.85535082 |
139 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.85485288 |
140 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.85446567 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.09665129 |
2 | MP0002396_abnormal_hematopoietic_system | 3.63136404 |
3 | MP0010094_abnormal_chromosome_stability | 3.38379634 |
4 | MP0009379_abnormal_foot_pigmentation | 3.27577435 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.00836189 |
6 | MP0005174_abnormal_tail_pigmentation | 2.96946001 |
7 | MP0008058_abnormal_DNA_repair | 2.90543857 |
8 | MP0003111_abnormal_nucleus_morphology | 2.85502048 |
9 | MP0000490_abnormal_crypts_of | 2.74592053 |
10 | MP0003077_abnormal_cell_cycle | 2.72354774 |
11 | MP0008057_abnormal_DNA_replication | 2.71129394 |
12 | MP0002877_abnormal_melanocyte_morpholog | 2.66812340 |
13 | MP0008007_abnormal_cellular_replicative | 2.57555398 |
14 | MP0001545_abnormal_hematopoietic_system | 2.45748950 |
15 | MP0005397_hematopoietic_system_phenotyp | 2.45748950 |
16 | MP0003705_abnormal_hypodermis_morpholog | 2.39464578 |
17 | MP0005451_abnormal_body_composition | 2.33497508 |
18 | MP0004808_abnormal_hematopoietic_stem | 2.28149509 |
19 | MP0005075_abnormal_melanosome_morpholog | 2.19811990 |
20 | MP0004233_abnormal_muscle_weight | 2.12496477 |
21 | MP0000685_abnormal_immune_system | 2.09553187 |
22 | MP0005076_abnormal_cell_differentiation | 2.03758275 |
23 | MP0006292_abnormal_olfactory_placode | 2.03222967 |
24 | MP0003763_abnormal_thymus_physiology | 2.02946155 |
25 | MP0009333_abnormal_splenocyte_physiolog | 1.96968128 |
26 | MP0001835_abnormal_antigen_presentation | 1.96424972 |
27 | MP0009672_abnormal_birth_weight | 1.92672025 |
28 | MP0000537_abnormal_urethra_morphology | 1.91783832 |
29 | MP0002398_abnormal_bone_marrow | 1.88410076 |
30 | MP0004185_abnormal_adipocyte_glucose | 1.88112501 |
31 | MP0002095_abnormal_skin_pigmentation | 1.84845058 |
32 | MP0010234_abnormal_vibrissa_follicle | 1.84721777 |
33 | MP0005671_abnormal_response_to | 1.78574537 |
34 | MP0004147_increased_porphyrin_level | 1.78540069 |
35 | MP0003786_premature_aging | 1.76706271 |
36 | MP0000015_abnormal_ear_pigmentation | 1.75818910 |
37 | MP0003984_embryonic_growth_retardation | 1.75306261 |
38 | MP0001188_hyperpigmentation | 1.68842964 |
39 | MP0000689_abnormal_spleen_morphology | 1.65903733 |
40 | MP0002088_abnormal_embryonic_growth/wei | 1.65732732 |
41 | MP0005501_abnormal_skin_physiology | 1.63823024 |
42 | MP0009785_altered_susceptibility_to | 1.61845862 |
43 | MP0002722_abnormal_immune_system | 1.61760210 |
44 | MP0000465_gastrointestinal_hemorrhage | 1.61373281 |
45 | MP0008932_abnormal_embryonic_tissue | 1.60998976 |
46 | MP0003566_abnormal_cell_adhesion | 1.59420181 |
47 | MP0001849_ear_inflammation | 1.57313446 |
48 | MP0010030_abnormal_orbit_morphology | 1.56633775 |
49 | MP0003724_increased_susceptibility_to | 1.55957799 |
50 | MP0002084_abnormal_developmental_patter | 1.53798606 |
51 | MP0006054_spinal_hemorrhage | 1.50962499 |
52 | MP0000678_abnormal_parathyroid_gland | 1.49065486 |
53 | MP0002796_impaired_skin_barrier | 1.48314510 |
54 | MP0005410_abnormal_fertilization | 1.47205173 |
55 | MP0002019_abnormal_tumor_incidence | 1.45570284 |
56 | MP0002429_abnormal_blood_cell | 1.43779437 |
57 | MP0000703_abnormal_thymus_morphology | 1.43428414 |
58 | MP0002086_abnormal_extraembryonic_tissu | 1.41581889 |
59 | MP0005409_darkened_coat_color | 1.41322607 |
60 | MP0000716_abnormal_immune_system | 1.40899259 |
61 | MP0005025_abnormal_response_to | 1.39945026 |
62 | MP0001800_abnormal_humoral_immune | 1.38105883 |
63 | MP0002210_abnormal_sex_determination | 1.35521327 |
64 | MP0002420_abnormal_adaptive_immunity | 1.34926286 |
65 | MP0000350_abnormal_cell_proliferation | 1.33771032 |
66 | MP0002132_abnormal_respiratory_system | 1.33467333 |
67 | MP0001819_abnormal_immune_cell | 1.32622496 |
68 | MP0004197_abnormal_fetal_growth/weight/ | 1.32332202 |
69 | MP0000313_abnormal_cell_death | 1.30822074 |
70 | MP0001929_abnormal_gametogenesis | 1.30480319 |
71 | MP0002723_abnormal_immune_serum | 1.28952818 |
72 | MP0002452_abnormal_antigen_presenting | 1.26327472 |
73 | MP0002102_abnormal_ear_morphology | 1.25100026 |
74 | MP0001873_stomach_inflammation | 1.23994270 |
75 | MP0001853_heart_inflammation | 1.22548014 |
76 | MP0008877_abnormal_DNA_methylation | 1.21993940 |
77 | MP0002697_abnormal_eye_size | 1.21404849 |
78 | MP0003436_decreased_susceptibility_to | 1.20538872 |
79 | MP0003941_abnormal_skin_development | 1.19876178 |
80 | MP0005464_abnormal_platelet_physiology | 1.19005313 |
81 | MP0000681_abnormal_thyroid_gland | 1.15611640 |
82 | MP0001986_abnormal_taste_sensitivity | 1.15396410 |
83 | MP0010155_abnormal_intestine_physiology | 1.14377398 |
84 | MP0001145_abnormal_male_reproductive | 1.14355794 |
85 | MP0005000_abnormal_immune_tolerance | 1.13686146 |
86 | MP0003866_abnormal_defecation | 1.12451407 |
87 | MP0004264_abnormal_extraembryonic_tissu | 1.12361845 |
88 | MP0006035_abnormal_mitochondrial_morpho | 1.10677820 |
89 | MP0003718_maternal_effect | 1.10633864 |
90 | MP0008260_abnormal_autophagy | 1.10007271 |
91 | MP0001730_embryonic_growth_arrest | 1.06740449 |
92 | MP0003567_abnormal_fetal_cardiomyocyte | 1.06606658 |
93 | MP0002405_respiratory_system_inflammati | 1.06152811 |
94 | MP0005623_abnormal_meninges_morphology | 1.05819457 |
95 | MP0001661_extended_life_span | 1.05360393 |
96 | MP0002166_altered_tumor_susceptibility | 1.05170267 |
97 | MP0002148_abnormal_hypersensitivity_rea | 1.02067434 |
98 | MP0002080_prenatal_lethality | 1.01959765 |
99 | MP0003656_abnormal_erythrocyte_physiolo | 1.01924377 |
100 | MP0005384_cellular_phenotype | 1.01753505 |
101 | MP0001727_abnormal_embryo_implantation | 1.01125196 |
102 | MP0009697_abnormal_copulation | 1.00777161 |
103 | MP0003698_abnormal_male_reproductive | 1.00003663 |
104 | MP0001348_abnormal_lacrimal_gland | 0.99195815 |
105 | MP0005621_abnormal_cell_physiology | 0.98724041 |
106 | MP0002060_abnormal_skin_morphology | 0.96982104 |
107 | MP0002089_abnormal_postnatal_growth/wei | 0.95873155 |
108 | MP0009278_abnormal_bone_marrow | 0.94064925 |
109 | MP0000653_abnormal_sex_gland | 0.91912119 |
110 | MP0003115_abnormal_respiratory_system | 0.91666567 |
111 | MP0001346_abnormal_lacrimal_gland | 0.90890775 |
112 | MP0002092_abnormal_eye_morphology | 0.90152764 |
113 | MP0000477_abnormal_intestine_morphology | 0.89785474 |
114 | MP0004272_abnormal_basement_membrane | 0.89619507 |
115 | MP0000858_altered_metastatic_potential | 0.89427836 |
116 | MP0009053_abnormal_anal_canal | 0.88786848 |
117 | MP0003221_abnormal_cardiomyocyte_apopto | 0.88498669 |
118 | MP0003303_peritoneal_inflammation | 0.88190543 |
119 | MP0003942_abnormal_urinary_system | 0.86826096 |
120 | MP0003937_abnormal_limbs/digits/tail_de | 0.86591954 |
121 | MP0002111_abnormal_tail_morphology | 0.86386451 |
122 | MP0009703_decreased_birth_body | 0.86190580 |
123 | MP0005257_abnormal_intraocular_pressure | 0.86102738 |
124 | MP0003385_abnormal_body_wall | 0.85758352 |
125 | MP0003453_abnormal_keratinocyte_physiol | 0.84787194 |
126 | MP0000358_abnormal_cell_content/ | 0.84574320 |
127 | MP0003123_paternal_imprinting | 0.84479609 |
128 | MP0001697_abnormal_embryo_size | 0.84364277 |
129 | MP0010307_abnormal_tumor_latency | 0.84000558 |
130 | MP0002160_abnormal_reproductive_system | 0.83742076 |
131 | MP0003868_abnormal_feces_composition | 0.83578714 |
132 | MP0000049_abnormal_middle_ear | 0.83281989 |
133 | MP0001293_anophthalmia | 0.83000735 |
134 | MP0003646_muscle_fatigue | 0.82210371 |
135 | MP0002938_white_spotting | 0.82110237 |
136 | MP0004858_abnormal_nervous_system | 0.81684806 |
137 | MP0002006_tumorigenesis | 0.81236030 |
138 | MP0000428_abnormal_craniofacial_morphol | 0.81192632 |
139 | MP0002075_abnormal_coat/hair_pigmentati | 0.80097071 |
140 | MP0002177_abnormal_outer_ear | 0.79646114 |
141 | MP0001915_intracranial_hemorrhage | 0.79528042 |
142 | MP0002419_abnormal_innate_immunity | 0.78897783 |
143 | MP0001216_abnormal_epidermal_layer | 0.78501825 |
144 | MP0000566_synostosis | 0.77318721 |
145 | MP0004782_abnormal_surfactant_physiolog | 0.76561007 |
146 | MP0000003_abnormal_adipose_tissue | 0.75965020 |
147 | MP0010352_gastrointestinal_tract_polyps | 0.75956700 |
148 | MP0000762_abnormal_tongue_morphology | 0.75872654 |
149 | MP0006036_abnormal_mitochondrial_physio | 0.75871301 |
150 | MP0003861_abnormal_nervous_system | 0.75474756 |
151 | MP0005666_abnormal_adipose_tissue | 0.75255190 |
152 | MP0003828_pulmonary_edema | 0.75020961 |
153 | MP0003315_abnormal_perineum_morphology | 0.74602819 |
154 | MP0002085_abnormal_embryonic_tissue | 0.73465166 |
155 | MP0002163_abnormal_gland_morphology | 0.72925995 |
156 | MP0001790_abnormal_immune_system | 0.72673558 |
157 | MP0005387_immune_system_phenotype | 0.72673558 |
158 | MP0001672_abnormal_embryogenesis/_devel | 0.72546570 |
159 | MP0005380_embryogenesis_phenotype | 0.72546570 |
160 | MP0001881_abnormal_mammary_gland | 0.70180810 |
161 | MP0000627_abnormal_mammary_gland | 0.69608704 |
162 | MP0003806_abnormal_nucleotide_metabolis | 0.69112073 |
163 | MP0010630_abnormal_cardiac_muscle | 0.68955539 |
164 | MP0000467_abnormal_esophagus_morphology | 0.68490280 |
165 | MP0001286_abnormal_eye_development | 0.67232738 |
166 | MP0000733_abnormal_muscle_development | 0.66952881 |
167 | MP0002249_abnormal_larynx_morphology | 0.66139907 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 6.23616204 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 6.17641380 |
3 | Reduced antithrombin III activity (HP:0001976) | 5.52647687 |
4 | Type I transferrin isoform profile (HP:0003642) | 5.31994369 |
5 | Reticulocytopenia (HP:0001896) | 4.93904696 |
6 | Aplastic anemia (HP:0001915) | 4.59208894 |
7 | Hyperacusis (HP:0010780) | 4.00267898 |
8 | Abnormal protein glycosylation (HP:0012346) | 3.97703235 |
9 | Abnormal glycosylation (HP:0012345) | 3.97703235 |
10 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.97703235 |
11 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.97703235 |
12 | Thrombocytosis (HP:0001894) | 3.96827653 |
13 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.94791255 |
14 | Pallor (HP:0000980) | 3.83418365 |
15 | Macrocytic anemia (HP:0001972) | 3.52215206 |
16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.37544451 |
17 | Increased nuchal translucency (HP:0010880) | 3.36094398 |
18 | Thyroid-stimulating hormone excess (HP:0002925) | 3.32724332 |
19 | Insomnia (HP:0100785) | 3.25175939 |
20 | Muscle fiber atrophy (HP:0100295) | 3.16739029 |
21 | Birth length less than 3rd percentile (HP:0003561) | 3.16462114 |
22 | IgM deficiency (HP:0002850) | 3.15949256 |
23 | Severe visual impairment (HP:0001141) | 3.12462150 |
24 | Multiple enchondromatosis (HP:0005701) | 3.04525560 |
25 | Type 2 muscle fiber atrophy (HP:0003554) | 3.00944720 |
26 | Chronic otitis media (HP:0000389) | 2.90824315 |
27 | Petechiae (HP:0000967) | 2.86679786 |
28 | Trismus (HP:0000211) | 2.85056201 |
29 | Deviation of the thumb (HP:0009603) | 2.82514633 |
30 | Proximal placement of thumb (HP:0009623) | 2.81283231 |
31 | Oral leukoplakia (HP:0002745) | 2.80281830 |
32 | Overriding aorta (HP:0002623) | 2.75866270 |
33 | Nasal polyposis (HP:0100582) | 2.71746679 |
34 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63904662 |
35 | Abnormality of the nasal mucosa (HP:0000433) | 2.63369462 |
36 | Myelodysplasia (HP:0002863) | 2.57179830 |
37 | Pancytopenia (HP:0001876) | 2.56316920 |
38 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.55718082 |
39 | Hypothermia (HP:0002045) | 2.55150898 |
40 | Prolonged bleeding time (HP:0003010) | 2.54409285 |
41 | Elfin facies (HP:0004428) | 2.53018339 |
42 | Poikiloderma (HP:0001029) | 2.50140098 |
43 | Cholecystitis (HP:0001082) | 2.48005155 |
44 | Abnormal gallbladder physiology (HP:0012438) | 2.48005155 |
45 | Recurrent bronchitis (HP:0002837) | 2.47865737 |
46 | Renal duplication (HP:0000075) | 2.46303242 |
47 | Abnormal spermatogenesis (HP:0008669) | 2.45581902 |
48 | Progressive external ophthalmoplegia (HP:0000590) | 2.43018993 |
49 | Selective tooth agenesis (HP:0001592) | 2.38867791 |
50 | Overlapping toe (HP:0001845) | 2.37538481 |
51 | Abnormality of T cell physiology (HP:0011840) | 2.36936203 |
52 | Abnormality of glycolysis (HP:0004366) | 2.34586241 |
53 | Abnormality of the preputium (HP:0100587) | 2.33146942 |
54 | Absent thumb (HP:0009777) | 2.33093201 |
55 | Asymmetry of the thorax (HP:0001555) | 2.31045671 |
56 | Panhypogammaglobulinemia (HP:0003139) | 2.30606662 |
57 | Microretrognathia (HP:0000308) | 2.29680115 |
58 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.29437236 |
59 | Acute lymphatic leukemia (HP:0006721) | 2.29161904 |
60 | 11 pairs of ribs (HP:0000878) | 2.28419410 |
61 | Amaurosis fugax (HP:0100576) | 2.26567222 |
62 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.24221518 |
63 | Broad distal phalanx of finger (HP:0009836) | 2.21171138 |
64 | Achilles tendon contracture (HP:0001771) | 2.20827980 |
65 | Ragged-red muscle fibers (HP:0003200) | 2.20380824 |
66 | Entropion (HP:0000621) | 2.19353034 |
67 | Microvesicular hepatic steatosis (HP:0001414) | 2.18148842 |
68 | Squamous cell carcinoma (HP:0002860) | 2.17852431 |
69 | Abnormality of reticulocytes (HP:0004312) | 2.17418029 |
70 | Abnormality of DNA repair (HP:0003254) | 2.16625011 |
71 | Long palpebral fissure (HP:0000637) | 2.16103782 |
72 | Acute myeloid leukemia (HP:0004808) | 2.15623573 |
73 | High anterior hairline (HP:0009890) | 2.15470803 |
74 | Abnormality of chromosome stability (HP:0003220) | 2.13209551 |
75 | Pendular nystagmus (HP:0012043) | 2.12290932 |
76 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.11627366 |
77 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.11627366 |
78 | Renovascular hypertension (HP:0100817) | 2.11250577 |
79 | Bone marrow hypocellularity (HP:0005528) | 2.10896372 |
80 | Patellar dislocation (HP:0002999) | 2.09369191 |
81 | Myositis (HP:0100614) | 2.09147643 |
82 | Progressive muscle weakness (HP:0003323) | 2.08942801 |
83 | Lymphoma (HP:0002665) | 2.08670597 |
84 | Meckel diverticulum (HP:0002245) | 2.08545668 |
85 | Spastic diplegia (HP:0001264) | 2.07627207 |
86 | Exertional dyspnea (HP:0002875) | 2.07248754 |
87 | Back pain (HP:0003418) | 2.07248032 |
88 | Colon cancer (HP:0003003) | 2.07092008 |
89 | Cortical dysplasia (HP:0002539) | 2.06721018 |
90 | Insidious onset (HP:0003587) | 2.05930270 |
91 | Termporal pattern (HP:0011008) | 2.05930270 |
92 | Chromsome breakage (HP:0040012) | 2.05630788 |
93 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.04106021 |
94 | Ankle contracture (HP:0006466) | 2.03288554 |
95 | Nonprogressive disorder (HP:0003680) | 2.03058610 |
96 | Atresia of the external auditory canal (HP:0000413) | 2.03007103 |
97 | Progressive hearing impairment (HP:0001730) | 2.03003246 |
98 | Abnormality of the ileum (HP:0001549) | 2.02814210 |
99 | Rough bone trabeculation (HP:0100670) | 2.02504174 |
100 | Abnormal platelet function (HP:0011869) | 2.02244411 |
101 | Impaired platelet aggregation (HP:0003540) | 2.02244411 |
102 | Ankyloglossia (HP:0010296) | 2.01031368 |
103 | Ulnar bowing (HP:0003031) | 2.00854376 |
104 | Facial cleft (HP:0002006) | 1.99505979 |
105 | Horseshoe kidney (HP:0000085) | 1.98874368 |
106 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.98693654 |
107 | Absent epiphyses (HP:0010577) | 1.98693654 |
108 | Hypoplasia of the radius (HP:0002984) | 1.98555831 |
109 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.96752757 |
110 | Epistaxis (HP:0000421) | 1.96479056 |
111 | Increased hepatocellular lipid droplets (HP:0006565) | 1.95565239 |
112 | Microcytic anemia (HP:0001935) | 1.95444036 |
113 | Urethral obstruction (HP:0000796) | 1.95258756 |
114 | Abnormality of the umbilical cord (HP:0010881) | 1.94136734 |
115 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.92733720 |
116 | Abnormality of the Achilles tendon (HP:0005109) | 1.91978904 |
117 | Increased serum pyruvate (HP:0003542) | 1.91620883 |
118 | Bronchitis (HP:0012387) | 1.90685830 |
119 | Distal lower limb amyotrophy (HP:0008944) | 1.90515812 |
120 | Abnormality of the columella (HP:0009929) | 1.90153462 |
121 | Basal cell carcinoma (HP:0002671) | 1.90095231 |
122 | Premature graying of hair (HP:0002216) | 1.89417433 |
123 | Abnormality of B cell number (HP:0010975) | 1.88525303 |
124 | B lymphocytopenia (HP:0010976) | 1.88525303 |
125 | Glossoptosis (HP:0000162) | 1.88420673 |
126 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.88368550 |
127 | Deep palmar crease (HP:0006191) | 1.87547684 |
128 | Missing ribs (HP:0000921) | 1.84833011 |
129 | IgG deficiency (HP:0004315) | 1.83904604 |
130 | Abnormality of cochlea (HP:0000375) | 1.83568890 |
131 | Abnormality of the carotid arteries (HP:0005344) | 1.83532774 |
132 | Unilateral renal agenesis (HP:0000122) | 1.83052739 |
133 | Reticulocytosis (HP:0001923) | 1.82386778 |
134 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.82052252 |
135 | Abnormal number of incisors (HP:0011064) | 1.81603200 |
136 | Upper limb amyotrophy (HP:0009129) | 1.81386297 |
137 | Distal upper limb amyotrophy (HP:0007149) | 1.81386297 |
138 | Abnormality of the calcaneus (HP:0008364) | 1.81201013 |
139 | Pointed chin (HP:0000307) | 1.81029235 |
140 | Medulloblastoma (HP:0002885) | 1.79590960 |
141 | Pulmonary fibrosis (HP:0002206) | 1.77611697 |
142 | Shoulder girdle muscle weakness (HP:0003547) | 1.76634421 |
143 | Abnormality of T cells (HP:0002843) | 1.75382099 |
144 | Abnormality of oral frenula (HP:0000190) | 1.74881857 |
145 | Supernumerary spleens (HP:0009799) | 1.74626562 |
146 | Orthostatic hypotension (HP:0001278) | 1.74468427 |
147 | Azoospermia (HP:0000027) | 1.74274702 |
148 | Neoplasm of the pancreas (HP:0002894) | 1.74253258 |
149 | Agnosia (HP:0010524) | 1.74233736 |
150 | Flat occiput (HP:0005469) | 1.73874275 |
151 | Recurrent viral infections (HP:0004429) | 1.72511181 |
152 | Cortical visual impairment (HP:0100704) | 1.72370385 |
153 | Sloping forehead (HP:0000340) | 1.72214670 |
154 | Clubbing of toes (HP:0100760) | 1.71583052 |
155 | Premature ovarian failure (HP:0008209) | 1.70990894 |
156 | Attenuation of retinal blood vessels (HP:0007843) | 1.70029693 |
157 | Respiratory difficulties (HP:0002880) | 1.70014716 |
158 | Small intestinal stenosis (HP:0012848) | 1.69738129 |
159 | Duodenal stenosis (HP:0100867) | 1.69738129 |
160 | Premature rupture of membranes (HP:0001788) | 1.69566247 |
161 | Vertebral compression fractures (HP:0002953) | 1.68637221 |
162 | Triphalangeal thumb (HP:0001199) | 1.68451672 |
163 | Breast hypoplasia (HP:0003187) | 1.68151645 |
164 | Microglossia (HP:0000171) | 1.66881709 |
165 | Choanal atresia (HP:0000453) | 1.66330372 |
166 | Pseudobulbar signs (HP:0002200) | 1.66215741 |
167 | Small epiphyses (HP:0010585) | 1.66148172 |
168 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.65833020 |
169 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.64513444 |
170 | Short nail (HP:0001799) | 1.64395505 |
171 | Breech presentation (HP:0001623) | 1.63917961 |
172 | Preauricular skin tag (HP:0000384) | 1.62247395 |
173 | Upper limb muscle weakness (HP:0003484) | 1.61855607 |
174 | Septate vagina (HP:0001153) | 1.61720121 |
175 | Embryonal renal neoplasm (HP:0011794) | 1.61652847 |
176 | Hand muscle atrophy (HP:0009130) | 1.61195998 |
177 | Pelvic girdle muscle weakness (HP:0003749) | 1.60256004 |
178 | Disproportionate tall stature (HP:0001519) | 1.59528794 |
179 | Increased connective tissue (HP:0009025) | 1.59502434 |
180 | Obsessive-compulsive behavior (HP:0000722) | 1.59360927 |
181 | Arnold-Chiari malformation (HP:0002308) | 1.59299852 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TNIK | 5.79244724 |
2 | WEE1 | 3.82186100 |
3 | SMG1 | 3.44422376 |
4 | NME2 | 3.34304036 |
5 | CDK12 | 3.21623097 |
6 | STK16 | 3.14215454 |
7 | TRIB3 | 2.92998074 |
8 | BUB1 | 2.64668219 |
9 | MKNK2 | 2.62134450 |
10 | EIF2AK3 | 2.58687572 |
11 | NLK | 2.47274799 |
12 | MUSK | 2.42181317 |
13 | CDC7 | 2.36154787 |
14 | FLT3 | 2.24251201 |
15 | ICK | 2.20962069 |
16 | KIT | 2.20943175 |
17 | VRK2 | 2.19373042 |
18 | MKNK1 | 2.19191557 |
19 | ACVR1B | 2.11813776 |
20 | PBK | 1.98576893 |
21 | EPHA2 | 1.98480412 |
22 | NEK2 | 1.97072226 |
23 | NEK1 | 1.92150291 |
24 | DYRK3 | 1.91177199 |
25 | PIM2 | 1.80480022 |
26 | EIF2AK1 | 1.74034737 |
27 | BRSK2 | 1.74023455 |
28 | TEC | 1.68981374 |
29 | VRK1 | 1.60708408 |
30 | EEF2K | 1.59804065 |
31 | MAP4K1 | 1.58064035 |
32 | TLK1 | 1.57682077 |
33 | SRPK1 | 1.56925036 |
34 | MST1R | 1.56332512 |
35 | CDK19 | 1.50878770 |
36 | CDK7 | 1.48946971 |
37 | TGFBR1 | 1.45701532 |
38 | BTK | 1.37976860 |
39 | SCYL2 | 1.27024142 |
40 | FES | 1.23017034 |
41 | LATS2 | 1.22404021 |
42 | RPS6KB2 | 1.21864481 |
43 | PASK | 1.20359170 |
44 | CDK4 | 1.17259695 |
45 | BLK | 1.15564626 |
46 | KDR | 1.15271433 |
47 | CSF1R | 1.14535155 |
48 | FGFR4 | 1.12773215 |
49 | CAMKK2 | 1.11353653 |
50 | ATR | 1.08757044 |
51 | TESK2 | 1.07537581 |
52 | ALK | 1.06913780 |
53 | RPS6KA4 | 1.02831584 |
54 | ARAF | 1.02305751 |
55 | PRPF4B | 0.99675838 |
56 | SIK1 | 0.99437653 |
57 | ZAP70 | 0.97203336 |
58 | MAP2K3 | 0.94854069 |
59 | MTOR | 0.94638830 |
60 | PLK1 | 0.93830777 |
61 | EIF2AK2 | 0.93678478 |
62 | BRD4 | 0.91570805 |
63 | TAF1 | 0.90176677 |
64 | MATK | 0.89913912 |
65 | NME1 | 0.88194133 |
66 | PLK3 | 0.88028042 |
67 | BRAF | 0.86156620 |
68 | AURKB | 0.84699317 |
69 | PDGFRA | 0.84284986 |
70 | PTK2 | 0.82145176 |
71 | PIM1 | 0.80367968 |
72 | CAMK1 | 0.80146904 |
73 | CCNB1 | 0.78799972 |
74 | CLK1 | 0.78426081 |
75 | STK10 | 0.77486666 |
76 | MET | 0.77130520 |
77 | TGFBR2 | 0.73795444 |
78 | TTN | 0.73561009 |
79 | CDK1 | 0.72518843 |
80 | TTK | 0.71321430 |
81 | JAK3 | 0.70352176 |
82 | IRAK4 | 0.70236345 |
83 | PAK4 | 0.70058522 |
84 | CHEK2 | 0.69992864 |
85 | PLK4 | 0.69269803 |
86 | CDK8 | 0.68502667 |
87 | BRSK1 | 0.68023497 |
88 | ERBB4 | 0.67438716 |
89 | STK4 | 0.67386252 |
90 | MAP3K8 | 0.66590839 |
91 | TSSK6 | 0.65505745 |
92 | TAOK2 | 0.64843934 |
93 | AKT2 | 0.64325826 |
94 | KSR2 | 0.64155589 |
95 | MAP3K9 | 0.63969170 |
96 | PTK6 | 0.63150489 |
97 | LYN | 0.62844731 |
98 | MAP3K11 | 0.62431020 |
99 | LRRK2 | 0.61974975 |
100 | ILK | 0.60600641 |
101 | MAPKAPK3 | 0.60376130 |
102 | CDK9 | 0.58901046 |
103 | SYK | 0.58622676 |
104 | CDK11A | 0.57895653 |
105 | CSNK2A2 | 0.57640184 |
106 | TBK1 | 0.56177821 |
107 | AURKA | 0.55084814 |
108 | MAP2K2 | 0.54563112 |
109 | MAP3K10 | 0.53049108 |
110 | TIE1 | 0.50946564 |
111 | PRKCI | 0.50656763 |
112 | IKBKB | 0.50628871 |
113 | DAPK1 | 0.50207556 |
114 | LCK | 0.49661712 |
115 | CSNK2A1 | 0.48816886 |
116 | YES1 | 0.48278270 |
117 | CHEK1 | 0.48234546 |
118 | CDK15 | 0.48085235 |
119 | MAPK4 | 0.47532287 |
120 | CDK14 | 0.46275570 |
121 | TXK | 0.45810112 |
122 | CDK18 | 0.45368954 |
123 | TYK2 | 0.45285241 |
124 | NTRK1 | 0.44924157 |
125 | RAF1 | 0.44423661 |
126 | LMTK2 | 0.44417051 |
127 | PDK4 | 0.44293476 |
128 | PDK3 | 0.44293476 |
129 | PRKG2 | 0.43988875 |
130 | CSNK1E | 0.43244791 |
131 | PKN2 | 0.42827270 |
132 | ATM | 0.41178375 |
133 | IRAK3 | 0.40661039 |
134 | BMX | 0.40604438 |
135 | ERN1 | 0.40075185 |
136 | PAK1 | 0.39034317 |
137 | PAK2 | 0.39031554 |
138 | LIMK1 | 0.38654181 |
139 | CAMK1D | 0.38524712 |
140 | ADRBK2 | 0.38418906 |
141 | BCKDK | 0.37621137 |
142 | MAPK11 | 0.36656010 |
143 | TESK1 | 0.34125271 |
144 | MAPK14 | 0.32834137 |
145 | HIPK2 | 0.32529524 |
146 | MAP3K6 | 0.32227063 |
147 | CDK2 | 0.30902749 |
148 | CDK6 | 0.30400715 |
149 | RPS6KA5 | 0.29587147 |
150 | DYRK1B | 0.29397047 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 5.43449459 |
2 | Ribosome_Homo sapiens_hsa03010 | 4.51697683 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.81770944 |
4 | Base excision repair_Homo sapiens_hsa03410 | 3.06292160 |
5 | Spliceosome_Homo sapiens_hsa03040 | 3.00639176 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 2.99310234 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.73092652 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.71264326 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.66030310 |
10 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.60395920 |
11 | RNA transport_Homo sapiens_hsa03013 | 2.24388250 |
12 | Proteasome_Homo sapiens_hsa03050 | 2.14745531 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.10860845 |
14 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.04851210 |
15 | Cell cycle_Homo sapiens_hsa04110 | 1.99900199 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.94415965 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.87683654 |
18 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.78963615 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.71217745 |
20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.67789900 |
21 | Sulfur relay system_Homo sapiens_hsa04122 | 1.64818850 |
22 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.64384776 |
23 | Thyroid cancer_Homo sapiens_hsa05216 | 1.62667562 |
24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.58996490 |
25 | Carbon metabolism_Homo sapiens_hsa01200 | 1.56356766 |
26 | Protein export_Homo sapiens_hsa03060 | 1.54254942 |
27 | RNA degradation_Homo sapiens_hsa03018 | 1.53029289 |
28 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.49825747 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.44256204 |
30 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.44059678 |
31 | Purine metabolism_Homo sapiens_hsa00230 | 1.43591172 |
32 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.39000537 |
33 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.36753171 |
34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.30859367 |
35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25448011 |
36 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.21160251 |
37 | Bladder cancer_Homo sapiens_hsa05219 | 1.14705996 |
38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.12943030 |
39 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.12702318 |
40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.10833579 |
41 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.10283427 |
42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.08922390 |
43 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.05244255 |
44 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.03228236 |
45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03022026 |
46 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.99109886 |
47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.94107274 |
48 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94016481 |
49 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.92856306 |
50 | Measles_Homo sapiens_hsa05162 | 0.92232796 |
51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.90207875 |
52 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.89973530 |
53 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.89960155 |
54 | Lysine degradation_Homo sapiens_hsa00310 | 0.89395345 |
55 | Adherens junction_Homo sapiens_hsa04520 | 0.83373102 |
56 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.82461820 |
57 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.82332775 |
58 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.77355079 |
59 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77210926 |
60 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76596515 |
61 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.74820127 |
62 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.71329375 |
63 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.70981903 |
64 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.70221329 |
65 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.69415060 |
66 | Endometrial cancer_Homo sapiens_hsa05213 | 0.68689868 |
67 | Other glycan degradation_Homo sapiens_hsa00511 | 0.67635247 |
68 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.64536563 |
69 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.64436806 |
70 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.63180461 |
71 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.63008209 |
72 | HTLV-I infection_Homo sapiens_hsa05166 | 0.59569540 |
73 | Legionellosis_Homo sapiens_hsa05134 | 0.56424403 |
74 | Leishmaniasis_Homo sapiens_hsa05140 | 0.56163274 |
75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56087801 |
76 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55926066 |
77 | Prostate cancer_Homo sapiens_hsa05215 | 0.55919026 |
78 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.55169622 |
79 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.54216901 |
80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.53289704 |
81 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.52787640 |
82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.52167360 |
83 | Shigellosis_Homo sapiens_hsa05131 | 0.51493431 |
84 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.51419077 |
85 | Hepatitis B_Homo sapiens_hsa05161 | 0.51073419 |
86 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50742123 |
87 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50169944 |
88 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.48726559 |
89 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.48300485 |
90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47635959 |
91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.47079629 |
92 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.46895520 |
93 | Influenza A_Homo sapiens_hsa05164 | 0.46537621 |
94 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.44692106 |
95 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.44557523 |
96 | Glioma_Homo sapiens_hsa05214 | 0.44464705 |
97 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.44177006 |
98 | Apoptosis_Homo sapiens_hsa04210 | 0.43708019 |
99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43381407 |
100 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.42633890 |
101 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41764178 |
102 | Prion diseases_Homo sapiens_hsa05020 | 0.41515960 |
103 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.41414216 |
104 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.40445946 |
105 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.39001545 |
106 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.38744715 |
107 | Tight junction_Homo sapiens_hsa04530 | 0.38585709 |
108 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.37762322 |
109 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37641600 |
110 | Colorectal cancer_Homo sapiens_hsa05210 | 0.36551583 |
111 | Allograft rejection_Homo sapiens_hsa05330 | 0.36535593 |
112 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.35618771 |
113 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.35354590 |
114 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.34712273 |
115 | Alcoholism_Homo sapiens_hsa05034 | 0.33457035 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.33379370 |
117 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.32843668 |
118 | Asthma_Homo sapiens_hsa05310 | 0.32754778 |
119 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.31459707 |
120 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.31065614 |
121 | Melanoma_Homo sapiens_hsa05218 | 0.30546467 |
122 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.30527080 |
123 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.29134046 |
124 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.28934718 |
125 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.26629670 |
126 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.25449963 |
127 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.25281210 |
128 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.25203022 |
129 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.24368512 |
130 | Malaria_Homo sapiens_hsa05144 | 0.23418830 |
131 | Platelet activation_Homo sapiens_hsa04611 | 0.23359275 |
132 | Pathways in cancer_Homo sapiens_hsa05200 | 0.22175352 |
133 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.21918550 |
134 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.21599521 |
135 | Metabolic pathways_Homo sapiens_hsa01100 | 0.20477687 |
136 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.20427703 |
137 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.19496519 |
138 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.19234145 |
139 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.18805557 |
140 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.17171812 |
141 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.16555525 |
142 | Pertussis_Homo sapiens_hsa05133 | 0.14731866 |
143 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.14432386 |
144 | Huntingtons disease_Homo sapiens_hsa05016 | 0.13934984 |
145 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.13775287 |
146 | Galactose metabolism_Homo sapiens_hsa00052 | 0.13577574 |