Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.37568805 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.24599066 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.24599066 |
4 | detection of other organism (GO:0098543) | 4.63735787 |
5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.59842692 |
6 | negative regulation of phagocytosis (GO:0050765) | 4.58138642 |
7 | detection of bacterium (GO:0016045) | 4.49461186 |
8 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.44248279 |
9 | macrophage activation involved in immune response (GO:0002281) | 4.39865705 |
10 | pinocytosis (GO:0006907) | 4.12108045 |
11 | cellular response to zinc ion (GO:0071294) | 4.01039907 |
12 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.98393802 |
13 | detection of external biotic stimulus (GO:0098581) | 3.97047070 |
14 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.89199478 |
15 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.82378980 |
16 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.78263418 |
17 | leukocyte aggregation (GO:0070486) | 3.75945490 |
18 | regulation of mast cell degranulation (GO:0043304) | 3.75473206 |
19 | regulation of B cell differentiation (GO:0045577) | 3.73347663 |
20 | detection of molecule of bacterial origin (GO:0032490) | 3.73321615 |
21 | positive regulation of B cell differentiation (GO:0045579) | 3.64703868 |
22 | regulation of T cell tolerance induction (GO:0002664) | 3.61421733 |
23 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.61066150 |
24 | respiratory burst (GO:0045730) | 3.60193722 |
25 | B cell receptor signaling pathway (GO:0050853) | 3.59049731 |
26 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.57456091 |
27 | low-density lipoprotein particle clearance (GO:0034383) | 3.57099523 |
28 | myeloid cell activation involved in immune response (GO:0002275) | 3.56580360 |
29 | pentose-phosphate shunt (GO:0006098) | 3.53336421 |
30 | positive regulation of mast cell activation (GO:0033005) | 3.51801221 |
31 | detection of biotic stimulus (GO:0009595) | 3.47850220 |
32 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.43037377 |
33 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.42649028 |
34 | negative regulation of T cell mediated immunity (GO:0002710) | 3.41163249 |
35 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.40286949 |
36 | immunoglobulin mediated immune response (GO:0016064) | 3.39112196 |
37 | regulation of leukocyte degranulation (GO:0043300) | 3.38171419 |
38 | regulation of tolerance induction (GO:0002643) | 3.35835874 |
39 | negative regulation of granulocyte differentiation (GO:0030853) | 3.35430987 |
40 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.34362397 |
41 | regulation of gamma-delta T cell activation (GO:0046643) | 3.34075476 |
42 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.33344915 |
43 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.31684628 |
44 | response to host immune response (GO:0052572) | 3.31684628 |
45 | blood vessel maturation (GO:0001955) | 3.24738601 |
46 | cellular response to interleukin-15 (GO:0071350) | 3.23859636 |
47 | regulation of mast cell activation (GO:0033003) | 3.20382230 |
48 | macrophage activation (GO:0042116) | 3.18991236 |
49 | cellular extravasation (GO:0045123) | 3.18081568 |
50 | germinal center formation (GO:0002467) | 3.17965207 |
51 | B cell mediated immunity (GO:0019724) | 3.15296355 |
52 | T cell selection (GO:0045058) | 3.14971210 |
53 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.14142222 |
54 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.14142222 |
55 | microglial cell activation (GO:0001774) | 3.13753057 |
56 | positive regulation of lamellipodium assembly (GO:0010592) | 3.12550676 |
57 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.11580819 |
58 | negative regulation of cell killing (GO:0031342) | 3.11580819 |
59 | natural killer cell differentiation (GO:0001779) | 3.09708516 |
60 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.08500925 |
61 | response to host (GO:0075136) | 3.08500925 |
62 | response to host defenses (GO:0052200) | 3.08500925 |
63 | positive regulation of mast cell degranulation (GO:0043306) | 3.07441305 |
64 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.07441305 |
65 | positive T cell selection (GO:0043368) | 3.07071636 |
66 | response to peptidoglycan (GO:0032494) | 3.06367605 |
67 | NADPH regeneration (GO:0006740) | 3.06328283 |
68 | leukocyte degranulation (GO:0043299) | 3.05613336 |
69 | thymic T cell selection (GO:0045061) | 3.04271474 |
70 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.02236121 |
71 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.01944797 |
72 | negative regulation of innate immune response (GO:0045824) | 3.01696794 |
73 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.98618204 |
74 | valine metabolic process (GO:0006573) | 2.97529526 |
75 | activated T cell proliferation (GO:0050798) | 2.95705838 |
76 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.95469134 |
77 | tolerance induction (GO:0002507) | 2.95126796 |
78 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.94768757 |
79 | positive thymic T cell selection (GO:0045059) | 2.94679798 |
80 | positive regulation of histone deacetylation (GO:0031065) | 2.93097332 |
81 | neutrophil activation involved in immune response (GO:0002283) | 2.92120852 |
82 | macrophage differentiation (GO:0030225) | 2.91912568 |
83 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.91821397 |
84 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.91068210 |
85 | regulation of antigen processing and presentation (GO:0002577) | 2.89456003 |
86 | regulation of cholesterol storage (GO:0010885) | 2.89299284 |
87 | negative regulation of interleukin-12 production (GO:0032695) | 2.88844150 |
88 | viral transcription (GO:0019083) | 2.86221359 |
89 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.85085407 |
90 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.83278084 |
91 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.82456480 |
92 | regulation of regulated secretory pathway (GO:1903305) | 2.82408558 |
93 | positive regulation of lamellipodium organization (GO:1902745) | 2.82230783 |
94 | ribosomal small subunit assembly (GO:0000028) | 2.80630549 |
95 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.79886127 |
96 | response to muramyl dipeptide (GO:0032495) | 2.79849016 |
97 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.79656158 |
98 | positive regulation of tolerance induction (GO:0002645) | 2.79067583 |
99 | actin nucleation (GO:0045010) | 2.78734755 |
100 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.78663477 |
101 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.78663477 |
102 | modulation by symbiont of host immune response (GO:0052553) | 2.78663477 |
103 | positive regulation by symbiont of host defense response (GO:0052509) | 2.78663477 |
104 | modulation by symbiont of host defense response (GO:0052031) | 2.78663477 |
105 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.78663477 |
106 | growth hormone receptor signaling pathway (GO:0060396) | 2.77616549 |
107 | NIK/NF-kappaB signaling (GO:0038061) | 2.77559025 |
108 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.75120173 |
109 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.73007497 |
110 | negative regulation of telomerase activity (GO:0051974) | 2.69363815 |
111 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.68028553 |
112 | translational termination (GO:0006415) | 2.67759955 |
113 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.67589087 |
114 | adaptation of signaling pathway (GO:0023058) | 2.66855717 |
115 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.64495520 |
116 | positive regulation of protein deacetylation (GO:0090312) | 2.62576286 |
117 | white fat cell differentiation (GO:0050872) | 2.61877603 |
118 | response to laminar fluid shear stress (GO:0034616) | 2.61041872 |
119 | angiogenesis involved in wound healing (GO:0060055) | 2.59120508 |
120 | response to fungus (GO:0009620) | 2.58983987 |
121 | positive regulation of macrophage differentiation (GO:0045651) | 2.57249900 |
122 | positive regulation of antigen processing and presentation (GO:0002579) | 2.54101862 |
123 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.54064339 |
124 | cellular response to interferon-beta (GO:0035458) | 2.53792174 |
125 | negative thymic T cell selection (GO:0045060) | 2.53525250 |
126 | mature B cell differentiation (GO:0002335) | 2.52942615 |
127 | defense response to protozoan (GO:0042832) | 2.52909791 |
128 | response to interleukin-15 (GO:0070672) | 2.52390983 |
129 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.51732433 |
130 | cellular response to growth hormone stimulus (GO:0071378) | 2.49579767 |
131 | neutrophil activation (GO:0042119) | 2.49166675 |
132 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.46059976 |
133 | myeloid dendritic cell activation (GO:0001773) | 2.45522914 |
134 | positive regulation of interferon-alpha production (GO:0032727) | 2.45415748 |
135 | response to protozoan (GO:0001562) | 2.44961510 |
136 | response to interferon-beta (GO:0035456) | 2.44825412 |
137 | negative T cell selection (GO:0043383) | 2.43103338 |
138 | lipid storage (GO:0019915) | 2.42230162 |
139 | myeloid dendritic cell differentiation (GO:0043011) | 2.41466584 |
140 | response to type I interferon (GO:0034340) | 2.40217418 |
141 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.37427160 |
142 | T cell migration (GO:0072678) | 2.36609754 |
143 | cellular response to type I interferon (GO:0071357) | 2.36457038 |
144 | type I interferon signaling pathway (GO:0060337) | 2.36457038 |
145 | leukocyte cell-cell adhesion (GO:0007159) | 2.36039009 |
146 | defense response to fungus (GO:0050832) | 2.34424547 |
147 | coronary vasculature morphogenesis (GO:0060977) | 2.33699795 |
148 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.33528145 |
149 | barbed-end actin filament capping (GO:0051016) | 2.33292773 |
150 | brown fat cell differentiation (GO:0050873) | 2.32064816 |
151 | regulation of interferon-alpha production (GO:0032647) | 2.30809936 |
152 | mature B cell differentiation involved in immune response (GO:0002313) | 2.30315547 |
153 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.28744438 |
154 | granulocyte activation (GO:0036230) | 2.27611129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.93166556 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.97311711 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.67173014 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.49046410 |
5 | * VDR_21846776_ChIP-Seq_THP-1_Human | 3.00311221 |
6 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.96937806 |
7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.83401638 |
8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.79635587 |
9 | MYC_22102868_ChIP-Seq_BL_Human | 2.77991294 |
10 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.65935302 |
11 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.57715680 |
12 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.56927829 |
13 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.52523100 |
14 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.49920156 |
15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.48885714 |
16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.39034583 |
17 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.35263394 |
18 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.33039115 |
19 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.32933209 |
20 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.27918009 |
21 | MAF_26560356_Chip-Seq_TH1_Human | 2.26426032 |
22 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.26264480 |
23 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.17430965 |
24 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.13722226 |
25 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.07602787 |
26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.00723348 |
27 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.99916046 |
28 | MYB_26560356_Chip-Seq_TH2_Human | 1.98995582 |
29 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.95124215 |
30 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.89005518 |
31 | MYB_26560356_Chip-Seq_TH1_Human | 1.86648636 |
32 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.86613797 |
33 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.85169244 |
34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.84404923 |
35 | UTX_26944678_Chip-Seq_JUKART_Human | 1.83642652 |
36 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.83548121 |
37 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.80383843 |
38 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.77012775 |
39 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.76676505 |
40 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.74144796 |
41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.70885767 |
42 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.70868423 |
43 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.68767161 |
44 | * MAF_26560356_Chip-Seq_TH2_Human | 1.61596530 |
45 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61466587 |
46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60866270 |
47 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.60725911 |
48 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.57502979 |
49 | SPI1_23127762_ChIP-Seq_K562_Human | 1.56459415 |
50 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.54259446 |
51 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.52270153 |
52 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.50789479 |
53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.45011940 |
54 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.44447623 |
55 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.42126411 |
56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41931432 |
57 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.39171125 |
58 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.37871733 |
59 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.37728352 |
60 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37214597 |
61 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.36542108 |
62 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33868073 |
63 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.30530578 |
64 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.27222907 |
65 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.26112927 |
66 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.25204379 |
67 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.23703513 |
68 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.23561814 |
69 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.22245100 |
70 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.22174002 |
71 | GATA1_19941826_ChIP-Seq_K562_Human | 1.21755629 |
72 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.21575592 |
73 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20597240 |
74 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20046565 |
75 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.18466972 |
76 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.18330311 |
77 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.17375764 |
78 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.17064399 |
79 | * CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16468082 |
80 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.15865231 |
81 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.15475340 |
82 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15432138 |
83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.15266126 |
84 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.15163111 |
85 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14181946 |
86 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.13364491 |
87 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.11643383 |
88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.11208506 |
89 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.10789529 |
90 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.08758774 |
91 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.08307804 |
92 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.07990533 |
93 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.06577712 |
94 | * PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06527194 |
95 | GATA3_26560356_Chip-Seq_TH2_Human | 1.05504250 |
96 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.05379027 |
97 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.05062192 |
98 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.05060808 |
99 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.04397218 |
100 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.04046004 |
101 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.04024832 |
102 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.01400498 |
103 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.00240657 |
104 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00048508 |
105 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98848649 |
106 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.98676682 |
107 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.97524828 |
108 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.96565066 |
109 | GATA1_22025678_ChIP-Seq_K562_Human | 0.96228951 |
110 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96126103 |
111 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.95733914 |
112 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94326076 |
113 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91870166 |
114 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91445422 |
115 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91144045 |
116 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.90617132 |
117 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90553115 |
118 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.90303040 |
119 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.90072192 |
120 | * P68_20966046_ChIP-Seq_HELA_Human | 0.88984432 |
121 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.87648195 |
122 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.87193911 |
123 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.86657537 |
124 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.84719832 |
125 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.82078476 |
126 | * PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.81836308 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.85444253 |
2 | MP0003303_peritoneal_inflammation | 3.59702258 |
3 | MP0000685_abnormal_immune_system | 3.06955205 |
4 | MP0003436_decreased_susceptibility_to | 2.76788002 |
5 | MP0005670_abnormal_white_adipose | 2.66893464 |
6 | MP0001790_abnormal_immune_system | 2.58599145 |
7 | MP0005387_immune_system_phenotype | 2.58599145 |
8 | MP0001800_abnormal_humoral_immune | 2.51184996 |
9 | MP0009785_altered_susceptibility_to | 2.44539746 |
10 | MP0003724_increased_susceptibility_to | 2.41995655 |
11 | MP0002452_abnormal_antigen_presenting | 2.39073776 |
12 | MP0002419_abnormal_innate_immunity | 2.32132869 |
13 | MP0003172_abnormal_lysosome_physiology | 2.25088847 |
14 | MP0005025_abnormal_response_to | 2.21283183 |
15 | MP0005000_abnormal_immune_tolerance | 2.20813662 |
16 | MP0002420_abnormal_adaptive_immunity | 2.13551292 |
17 | MP0001853_heart_inflammation | 2.13276353 |
18 | MP0001819_abnormal_immune_cell | 2.12965236 |
19 | MP0003300_gastrointestinal_ulcer | 2.11267146 |
20 | MP0005671_abnormal_response_to | 2.08990790 |
21 | MP0002723_abnormal_immune_serum | 2.07802319 |
22 | MP0009278_abnormal_bone_marrow | 1.95100343 |
23 | MP0008438_abnormal_cutaneous_collagen | 1.94253146 |
24 | MP0002396_abnormal_hematopoietic_system | 1.89607070 |
25 | MP0002148_abnormal_hypersensitivity_rea | 1.89039714 |
26 | MP0002166_altered_tumor_susceptibility | 1.88073201 |
27 | MP0005666_abnormal_adipose_tissue | 1.87948460 |
28 | MP0002398_abnormal_bone_marrow | 1.87810195 |
29 | MP0008260_abnormal_autophagy | 1.82906136 |
30 | MP0000343_altered_response_to | 1.82776059 |
31 | MP0000858_altered_metastatic_potential | 1.77892239 |
32 | MP0000716_abnormal_immune_system | 1.75305528 |
33 | MP0002405_respiratory_system_inflammati | 1.75302500 |
34 | MP0004808_abnormal_hematopoietic_stem | 1.75094384 |
35 | MP0005464_abnormal_platelet_physiology | 1.73512985 |
36 | MP0000689_abnormal_spleen_morphology | 1.68627541 |
37 | MP0003763_abnormal_thymus_physiology | 1.59617852 |
38 | MP0001533_abnormal_skeleton_physiology | 1.58501086 |
39 | MP0001545_abnormal_hematopoietic_system | 1.57002234 |
40 | MP0005397_hematopoietic_system_phenotyp | 1.57002234 |
41 | MP0004185_abnormal_adipocyte_glucose | 1.56022867 |
42 | MP0005076_abnormal_cell_differentiation | 1.54840762 |
43 | MP0003705_abnormal_hypodermis_morpholog | 1.54002240 |
44 | MP0003448_altered_tumor_morphology | 1.53824173 |
45 | MP0003191_abnormal_cellular_cholesterol | 1.53533195 |
46 | MP0003279_aneurysm | 1.53285324 |
47 | MP0010155_abnormal_intestine_physiology | 1.53067950 |
48 | MP0002429_abnormal_blood_cell | 1.52590623 |
49 | MP0009333_abnormal_splenocyte_physiolog | 1.51596593 |
50 | MP0009840_abnormal_foam_cell | 1.50263137 |
51 | MP0002006_tumorigenesis | 1.49164036 |
52 | MP0002722_abnormal_immune_system | 1.48586587 |
53 | MP0005310_abnormal_salivary_gland | 1.45589834 |
54 | MP0001845_abnormal_inflammatory_respons | 1.45561703 |
55 | MP0005451_abnormal_body_composition | 1.43670255 |
56 | MP0003566_abnormal_cell_adhesion | 1.38166275 |
57 | MP0003866_abnormal_defecation | 1.35794620 |
58 | MP0002132_abnormal_respiratory_system | 1.34814497 |
59 | MP0000604_amyloidosis | 1.30381181 |
60 | MP0010307_abnormal_tumor_latency | 1.27256051 |
61 | MP0001958_emphysema | 1.25945849 |
62 | MP0005167_abnormal_blood-brain_barrier | 1.25530539 |
63 | MP0003828_pulmonary_edema | 1.22760808 |
64 | MP0010352_gastrointestinal_tract_polyps | 1.21980614 |
65 | MP0008469_abnormal_protein_level | 1.21070134 |
66 | MP0004510_myositis | 1.20386996 |
67 | MP0004883_abnormal_blood_vessel | 1.18303133 |
68 | MP0004381_abnormal_hair_follicle | 1.16794782 |
69 | MP0004272_abnormal_basement_membrane | 1.15593458 |
70 | MP0009115_abnormal_fat_cell | 1.12261534 |
71 | MP0005375_adipose_tissue_phenotype | 1.11868385 |
72 | MP0004130_abnormal_muscle_cell | 1.10871493 |
73 | MP0001879_abnormal_lymphatic_vessel | 1.09582706 |
74 | MP0001873_stomach_inflammation | 1.09214066 |
75 | MP0002933_joint_inflammation | 1.08864927 |
76 | MP0000703_abnormal_thymus_morphology | 1.05718729 |
77 | MP0009764_decreased_sensitivity_to | 1.03982946 |
78 | MP0002019_abnormal_tumor_incidence | 1.02855856 |
79 | MP0008004_abnormal_stomach_pH | 1.01793567 |
80 | MP0002971_abnormal_brown_adipose | 1.01477515 |
81 | MP0006082_CNS_inflammation | 0.97170041 |
82 | MP0005023_abnormal_wound_healing | 0.96913535 |
83 | MP0005058_abnormal_lysosome_morphology | 0.96293924 |
84 | MP0003091_abnormal_cell_migration | 0.95904367 |
85 | MP0004947_skin_inflammation | 0.95896014 |
86 | MP0000490_abnormal_crypts_of | 0.92826547 |
87 | MP0000465_gastrointestinal_hemorrhage | 0.90028479 |
88 | MP0002277_abnormal_respiratory_mucosa | 0.89623078 |
89 | MP0000249_abnormal_blood_vessel | 0.89538542 |
90 | MP0002970_abnormal_white_adipose | 0.89374379 |
91 | MP0009763_increased_sensitivity_to | 0.88254686 |
92 | MP0003186_abnormal_redox_activity | 0.87881936 |
93 | MP0006054_spinal_hemorrhage | 0.87514721 |
94 | MP0003045_fibrosis | 0.87275329 |
95 | MP0005174_abnormal_tail_pigmentation | 0.85664046 |
96 | MP0003806_abnormal_nucleotide_metabolis | 0.85213789 |
97 | MP0000609_abnormal_liver_physiology | 0.84274699 |
98 | MP0001851_eye_inflammation | 0.83387029 |
99 | MP0003795_abnormal_bone_structure | 0.78635864 |
100 | MP0002138_abnormal_hepatobiliary_system | 0.76816617 |
101 | MP0003656_abnormal_erythrocyte_physiolo | 0.76762059 |
102 | MP0001663_abnormal_digestive_system | 0.76635622 |
103 | MP0005334_abnormal_fat_pad | 0.76114025 |
104 | MP0000015_abnormal_ear_pigmentation | 0.75825880 |
105 | MP0010368_abnormal_lymphatic_system | 0.73211831 |
106 | MP0010329_abnormal_lipoprotein_level | 0.73109441 |
107 | MP0005075_abnormal_melanosome_morpholog | 0.71345145 |
108 | MP0002998_abnormal_bone_remodeling | 0.71332605 |
109 | MP0000598_abnormal_liver_morphology | 0.70754862 |
110 | MP0005390_skeleton_phenotype | 0.70326838 |
111 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.70102952 |
112 | MP0001986_abnormal_taste_sensitivity | 0.69609860 |
113 | MP0005164_abnormal_response_to | 0.69221743 |
114 | MP0003183_abnormal_peptide_metabolism | 0.69099194 |
115 | MP0005166_decreased_susceptibility_to | 0.69006317 |
116 | MP0003690_abnormal_glial_cell | 0.68192227 |
117 | MP0008961_abnormal_basal_metabolism | 0.67705927 |
118 | MP0003077_abnormal_cell_cycle | 0.67317653 |
119 | MP0008874_decreased_physiological_sensi | 0.66978597 |
120 | MP0003453_abnormal_keratinocyte_physiol | 0.66747560 |
121 | MP0003075_altered_response_to | 0.66209872 |
122 | MP0002877_abnormal_melanocyte_morpholog | 0.66152699 |
123 | MP0000920_abnormal_myelination | 0.64751130 |
124 | MP0003329_amyloid_beta_deposits | 0.60265748 |
125 | MP0009765_abnormal_xenobiotic_induced | 0.60232121 |
126 | MP0001542_abnormal_bone_strength | 0.51385738 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 5.06888383 |
2 | Eczematoid dermatitis (HP:0000976) | 4.97334871 |
3 | Recurrent bacterial skin infections (HP:0005406) | 4.41601696 |
4 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.13020432 |
5 | Cellulitis (HP:0100658) | 3.96075911 |
6 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.92106377 |
7 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.92106377 |
8 | Abnormality of glycolipid metabolism (HP:0010969) | 3.92106377 |
9 | Optic neuritis (HP:0100653) | 3.88412042 |
10 | Retrobulbar optic neuritis (HP:0100654) | 3.88412042 |
11 | Chronic otitis media (HP:0000389) | 3.57989144 |
12 | Gastrointestinal infarctions (HP:0005244) | 3.55545349 |
13 | Abnormality of macrophages (HP:0004311) | 3.47340888 |
14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.47173338 |
15 | Recurrent bronchitis (HP:0002837) | 3.42788885 |
16 | Mediastinal lymphadenopathy (HP:0100721) | 3.41986067 |
17 | Gastrointestinal inflammation (HP:0004386) | 3.41587632 |
18 | Recurrent fungal infections (HP:0002841) | 3.38267225 |
19 | Recurrent viral infections (HP:0004429) | 3.31110783 |
20 | Myositis (HP:0100614) | 3.28959982 |
21 | Meningitis (HP:0001287) | 3.21828736 |
22 | IgM deficiency (HP:0002850) | 3.20047769 |
23 | Chronic obstructive pulmonary disease (HP:0006510) | 3.19153652 |
24 | Obstructive lung disease (HP:0006536) | 3.19153652 |
25 | Colitis (HP:0002583) | 3.10641575 |
26 | Vacuolated lymphocytes (HP:0001922) | 3.09044459 |
27 | Recurrent skin infections (HP:0001581) | 3.08676489 |
28 | Inflammation of the large intestine (HP:0002037) | 3.06645999 |
29 | Abnormality of the nasal mucosa (HP:0000433) | 3.05940284 |
30 | Encephalitis (HP:0002383) | 3.03464220 |
31 | Agammaglobulinemia (HP:0004432) | 3.03154890 |
32 | Dysostosis multiplex (HP:0000943) | 3.00979179 |
33 | Nasal polyposis (HP:0100582) | 2.99759442 |
34 | Increased IgE level (HP:0003212) | 2.98469926 |
35 | Autoimmune thrombocytopenia (HP:0001973) | 2.97558358 |
36 | Thrombocytosis (HP:0001894) | 2.96842989 |
37 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.90951448 |
38 | Pulmonary infiltrates (HP:0002113) | 2.85823441 |
39 | Spontaneous hematomas (HP:0007420) | 2.83069299 |
40 | Petechiae (HP:0000967) | 2.81056794 |
41 | Keratoconjunctivitis sicca (HP:0001097) | 2.80547512 |
42 | Systemic lupus erythematosus (HP:0002725) | 2.79621591 |
43 | Gingivitis (HP:0000230) | 2.63120256 |
44 | Cerebral aneurysm (HP:0004944) | 2.62184776 |
45 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.55403721 |
46 | Keratoconjunctivitis (HP:0001096) | 2.54716581 |
47 | Recurrent cutaneous fungal infections (HP:0011370) | 2.53576395 |
48 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.53576395 |
49 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.51259455 |
50 | Lymphopenia (HP:0001888) | 2.49852543 |
51 | Leukocytosis (HP:0001974) | 2.49207660 |
52 | Recurrent sinusitis (HP:0011108) | 2.48619783 |
53 | Osteomyelitis (HP:0002754) | 2.48147257 |
54 | Vasculitis (HP:0002633) | 2.47842402 |
55 | Prolonged bleeding time (HP:0003010) | 2.47737644 |
56 | Emphysema (HP:0002097) | 2.46910017 |
57 | Interstitial pulmonary disease (HP:0006530) | 2.45201307 |
58 | Gastrointestinal stroma tumor (HP:0100723) | 2.44525042 |
59 | Hematochezia (HP:0002573) | 2.40924812 |
60 | Abnormality of T cells (HP:0002843) | 2.38704686 |
61 | Abnormality of T cell physiology (HP:0011840) | 2.37550179 |
62 | Amyloidosis (HP:0011034) | 2.36368326 |
63 | Cervical subluxation (HP:0003308) | 2.35738859 |
64 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.35656300 |
65 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.35656300 |
66 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.35656300 |
67 | Episodic fever (HP:0001954) | 2.35258388 |
68 | Pulmonary embolism (HP:0002204) | 2.34363374 |
69 | Increased IgM level (HP:0003496) | 2.32514277 |
70 | Reticulocytopenia (HP:0001896) | 2.32145101 |
71 | Porencephaly (HP:0002132) | 2.30490504 |
72 | Recurrent lower respiratory tract infections (HP:0002783) | 2.30153528 |
73 | Panhypogammaglobulinemia (HP:0003139) | 2.29258831 |
74 | Papilloma (HP:0012740) | 2.28360797 |
75 | Verrucae (HP:0200043) | 2.28360797 |
76 | Urticaria (HP:0001025) | 2.28311355 |
77 | Stomatitis (HP:0010280) | 2.27559605 |
78 | Myocardial infarction (HP:0001658) | 2.23671955 |
79 | Granulocytopenia (HP:0001913) | 2.23541376 |
80 | Abnormal platelet volume (HP:0011876) | 2.23281141 |
81 | Tetraparesis (HP:0002273) | 2.21918363 |
82 | Increased serum ferritin (HP:0003281) | 2.21071954 |
83 | Hypertriglyceridemia (HP:0002155) | 2.18898333 |
84 | Anorexia (HP:0002039) | 2.18175774 |
85 | Hypochromic anemia (HP:0001931) | 2.14754636 |
86 | Abnormality of T cell number (HP:0011839) | 2.12952456 |
87 | T lymphocytopenia (HP:0005403) | 2.12753551 |
88 | Recurrent pneumonia (HP:0006532) | 2.12601948 |
89 | Restrictive lung disease (HP:0002091) | 2.11790334 |
90 | Hypergammaglobulinemia (HP:0010702) | 2.10652548 |
91 | Hepatosplenomegaly (HP:0001433) | 2.08435549 |
92 | Slow saccadic eye movements (HP:0000514) | 2.07252191 |
93 | Disinhibition (HP:0000734) | 2.06434458 |
94 | Premature loss of primary teeth (HP:0006323) | 2.03137556 |
95 | Epistaxis (HP:0000421) | 2.01351492 |
96 | Abnormality of the lumbar spine (HP:0100712) | 2.01302294 |
97 | Skin ulcer (HP:0200042) | 1.99141352 |
98 | Abnormal platelet function (HP:0011869) | 1.98983198 |
99 | Impaired platelet aggregation (HP:0003540) | 1.98983198 |
100 | Bronchitis (HP:0012387) | 1.98029052 |
101 | Increased cerebral lipofuscin (HP:0011813) | 1.96820271 |
102 | Abnormality of the pleura (HP:0002103) | 1.95838837 |
103 | Ankle contracture (HP:0006466) | 1.95493070 |
104 | Hypochromic microcytic anemia (HP:0004840) | 1.95472463 |
105 | Arterial thrombosis (HP:0004420) | 1.94610486 |
106 | Multiple enchondromatosis (HP:0005701) | 1.94493587 |
107 | Purpura (HP:0000979) | 1.94216469 |
108 | Chronic sinusitis (HP:0011109) | 1.93913820 |
109 | B lymphocytopenia (HP:0010976) | 1.93203534 |
110 | Abnormality of B cell number (HP:0010975) | 1.93203534 |
111 | Acanthosis nigricans (HP:0000956) | 1.92426988 |
112 | Abnormality of iron homeostasis (HP:0011031) | 1.92139330 |
113 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.91765478 |
114 | Mucopolysacchariduria (HP:0008155) | 1.91765478 |
115 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.91640661 |
116 | Glomerulopathy (HP:0100820) | 1.90786548 |
117 | Chest pain (HP:0100749) | 1.90693310 |
118 | Hemoptysis (HP:0002105) | 1.90046996 |
119 | Gingival bleeding (HP:0000225) | 1.89924627 |
120 | Polygenic inheritance (HP:0010982) | 1.89401209 |
121 | Increased density of long bones (HP:0006392) | 1.88518805 |
122 | Microcytic anemia (HP:0001935) | 1.88097113 |
123 | Gangrene (HP:0100758) | 1.84819415 |
124 | Increased mean platelet volume (HP:0011877) | 1.83813736 |
125 | Orchitis (HP:0100796) | 1.83485685 |
126 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.82478960 |
127 | Upper motor neuron abnormality (HP:0002127) | 1.82312826 |
128 | Arthralgia (HP:0002829) | 1.81719371 |
129 | Osteolytic defects of the hand bones (HP:0009699) | 1.81299621 |
130 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.81299621 |
131 | Polyneuropathy (HP:0001271) | 1.81162533 |
132 | Loss of speech (HP:0002371) | 1.80679348 |
133 | Protrusio acetabuli (HP:0003179) | 1.80592372 |
134 | Abnormality of the peritoneum (HP:0002585) | 1.78661088 |
135 | Growth hormone excess (HP:0000845) | 1.77239839 |
136 | Bicuspid aortic valve (HP:0001647) | 1.76856224 |
137 | Peritonitis (HP:0002586) | 1.76792141 |
138 | Leukopenia (HP:0001882) | 1.76540396 |
139 | Periodontitis (HP:0000704) | 1.76010371 |
140 | Ulnar deviation of the wrist (HP:0003049) | 1.75934997 |
141 | Sepsis (HP:0100806) | 1.73894461 |
142 | Pustule (HP:0200039) | 1.72814129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 4.09221047 |
2 | TRIB3 | 3.30049851 |
3 | PRPF4B | 2.72860843 |
4 | CCNB1 | 2.49801411 |
5 | CSF1R | 2.40114647 |
6 | ERN1 | 2.37357374 |
7 | TYK2 | 2.27362606 |
8 | BTK | 2.25498583 |
9 | BLK | 2.21064644 |
10 | NME2 | 2.20010646 |
11 | IRAK4 | 2.13808889 |
12 | KIT | 2.08710832 |
13 | CAMK1D | 2.02611196 |
14 | LRRK2 | 1.99853153 |
15 | MAP3K10 | 1.95997910 |
16 | STK10 | 1.88305158 |
17 | JAK3 | 1.86095870 |
18 | TBK1 | 1.69272591 |
19 | TEC | 1.67871862 |
20 | CSK | 1.67482370 |
21 | GRK6 | 1.64018598 |
22 | EEF2K | 1.63876098 |
23 | PKN2 | 1.61600181 |
24 | SIK1 | 1.60625964 |
25 | TGFBR2 | 1.58634679 |
26 | ZAP70 | 1.50938855 |
27 | EPHB1 | 1.48693336 |
28 | FLT3 | 1.43489997 |
29 | FES | 1.43056394 |
30 | RPS6KA4 | 1.40816872 |
31 | MAP3K14 | 1.40352919 |
32 | TAOK1 | 1.38895758 |
33 | IRAK3 | 1.38252149 |
34 | MAP2K3 | 1.37796334 |
35 | CDK4 | 1.36868875 |
36 | IKBKB | 1.35433488 |
37 | HCK | 1.27159033 |
38 | SYK | 1.26886279 |
39 | NEK9 | 1.25228616 |
40 | CDK6 | 1.25013074 |
41 | RIPK4 | 1.19903363 |
42 | CLK1 | 1.19229591 |
43 | FGFR3 | 1.18731216 |
44 | ITK | 1.18722024 |
45 | IKBKE | 1.18240271 |
46 | JAK1 | 1.15421423 |
47 | ACVR1B | 1.13964334 |
48 | RIPK1 | 1.13803083 |
49 | CAMK1G | 1.12208445 |
50 | PTK6 | 1.12176636 |
51 | MAP3K1 | 1.11936626 |
52 | TTN | 1.11508430 |
53 | CDC42BPA | 1.06664084 |
54 | PAK4 | 1.04866751 |
55 | TAOK2 | 1.02640758 |
56 | MARK2 | 1.01578030 |
57 | KDR | 0.99823014 |
58 | KSR2 | 0.98480061 |
59 | TAOK3 | 0.97779292 |
60 | TESK2 | 0.97240434 |
61 | NEK2 | 0.97096553 |
62 | SCYL2 | 0.96643389 |
63 | LCK | 0.96565315 |
64 | MAP3K6 | 0.94818563 |
65 | LYN | 0.93859044 |
66 | FGFR4 | 0.93680215 |
67 | CAMKK2 | 0.93180594 |
68 | PIM1 | 0.92126378 |
69 | MAP3K13 | 0.92118438 |
70 | MAPK12 | 0.91993012 |
71 | MAPK4 | 0.90456502 |
72 | SIK2 | 0.90222824 |
73 | PDPK1 | 0.88624747 |
74 | CDK9 | 0.85774993 |
75 | SMG1 | 0.83013190 |
76 | GRK7 | 0.80670427 |
77 | JAK2 | 0.78775226 |
78 | BMPR2 | 0.78313024 |
79 | YES1 | 0.77231111 |
80 | MAPK7 | 0.75578464 |
81 | BCKDK | 0.73869183 |
82 | IRAK2 | 0.70728740 |
83 | CAMKK1 | 0.70693619 |
84 | MAP3K3 | 0.70676703 |
85 | MAP3K8 | 0.66898069 |
86 | PRKCQ | 0.66421065 |
87 | MARK3 | 0.66308714 |
88 | ALK | 0.63555524 |
89 | FYN | 0.63317233 |
90 | TRPM7 | 0.62926286 |
91 | MAP3K7 | 0.62661471 |
92 | WEE1 | 0.59779742 |
93 | DMPK | 0.59114220 |
94 | NLK | 0.58203074 |
95 | SIK3 | 0.56376086 |
96 | HIPK2 | 0.56365803 |
97 | TLK1 | 0.56283558 |
98 | MAPKAPK3 | 0.55704320 |
99 | MAPKAPK2 | 0.54638542 |
100 | MAP3K11 | 0.54345233 |
101 | RPS6KL1 | 0.52471152 |
102 | RPS6KC1 | 0.52471152 |
103 | ABL1 | 0.50593576 |
104 | STK4 | 0.50582498 |
105 | CDK12 | 0.50049259 |
106 | BMX | 0.47982477 |
107 | IRAK1 | 0.46923975 |
108 | MOS | 0.46283130 |
109 | PIK3CG | 0.46190255 |
110 | ATR | 0.45538035 |
111 | RET | 0.45350519 |
112 | DYRK1B | 0.45160971 |
113 | MATK | 0.44352419 |
114 | MAP3K5 | 0.44234870 |
115 | BUB1 | 0.43960013 |
116 | MAPK11 | 0.43289990 |
117 | CDK19 | 0.43148972 |
118 | MAP2K6 | 0.41813650 |
119 | PTK2B | 0.41272454 |
120 | EGFR | 0.40842931 |
121 | FGR | 0.40704268 |
122 | TXK | 0.39883378 |
123 | RPS6KA2 | 0.39702907 |
124 | PIM2 | 0.39053385 |
125 | PRKD2 | 0.38347529 |
126 | SGK3 | 0.38174695 |
127 | CHUK | 0.37367827 |
128 | TNK2 | 0.36105491 |
129 | TESK1 | 0.35892278 |
130 | PDGFRB | 0.35883491 |
131 | EIF2AK1 | 0.33715551 |
132 | RPS6KA6 | 0.33582406 |
133 | PDK1 | 0.33347105 |
134 | TGFBR1 | 0.33111384 |
135 | STK38 | 0.32172892 |
136 | MAP3K2 | 0.32087166 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.03549373 |
2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.67499485 |
3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.60532874 |
4 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.47955725 |
5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.42967633 |
6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.40516598 |
7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.19677348 |
8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.85405814 |
9 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.84722831 |
10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.83497939 |
11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.82753319 |
12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.81772488 |
13 | Other glycan degradation_Homo sapiens_hsa00511 | 1.79830148 |
14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.70716682 |
15 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.68792012 |
16 | Shigellosis_Homo sapiens_hsa05131 | 1.64755377 |
17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.62607329 |
18 | Base excision repair_Homo sapiens_hsa03410 | 1.61912823 |
19 | Asthma_Homo sapiens_hsa05310 | 1.60054501 |
20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.59605061 |
21 | Ribosome_Homo sapiens_hsa03010 | 1.56560370 |
22 | Legionellosis_Homo sapiens_hsa05134 | 1.54096765 |
23 | Measles_Homo sapiens_hsa05162 | 1.53044199 |
24 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.51069810 |
25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.50271033 |
26 | Pertussis_Homo sapiens_hsa05133 | 1.47908363 |
27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.47488989 |
28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.47293302 |
29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.44940375 |
30 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.43870990 |
31 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.41493209 |
32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.41229662 |
33 | Mismatch repair_Homo sapiens_hsa03430 | 1.40442280 |
34 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.40029148 |
35 | Malaria_Homo sapiens_hsa05144 | 1.39909428 |
36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.36890690 |
37 | Tuberculosis_Homo sapiens_hsa05152 | 1.36412200 |
38 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.32080224 |
39 | Hepatitis B_Homo sapiens_hsa05161 | 1.30625959 |
40 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.28981629 |
41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.24642140 |
42 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.23439664 |
43 | Apoptosis_Homo sapiens_hsa04210 | 1.22680332 |
44 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.22081008 |
45 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.21255782 |
46 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.19821717 |
47 | Platelet activation_Homo sapiens_hsa04611 | 1.18202998 |
48 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.18199273 |
49 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.18048806 |
50 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.14288178 |
51 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.13605692 |
52 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.09439464 |
53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.08863558 |
54 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.07259837 |
55 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.07053956 |
56 | Salmonella infection_Homo sapiens_hsa05132 | 1.06044691 |
57 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.05353605 |
58 | Homologous recombination_Homo sapiens_hsa03440 | 1.05298523 |
59 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.04229768 |
60 | HTLV-I infection_Homo sapiens_hsa05166 | 1.02518153 |
61 | Influenza A_Homo sapiens_hsa05164 | 1.00795963 |
62 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.98459439 |
63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.98219681 |
64 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.94480945 |
65 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.94368352 |
66 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.93749779 |
67 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.93708072 |
68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.93085571 |
69 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.89165610 |
70 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.89020094 |
71 | Insulin resistance_Homo sapiens_hsa04931 | 0.88839386 |
72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.86825383 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.86175509 |
74 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.85072376 |
75 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.84403438 |
76 | Endocytosis_Homo sapiens_hsa04144 | 0.81077439 |
77 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.80875539 |
78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.77071815 |
79 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.73044444 |
80 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.72663333 |
81 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70039625 |
82 | Focal adhesion_Homo sapiens_hsa04510 | 0.69407204 |
83 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.69197500 |
84 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.68487970 |
85 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.67980128 |
86 | Spliceosome_Homo sapiens_hsa03040 | 0.66940129 |
87 | Lysosome_Homo sapiens_hsa04142 | 0.66724704 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.65648507 |
89 | Hepatitis C_Homo sapiens_hsa05160 | 0.64469384 |
90 | Allograft rejection_Homo sapiens_hsa05330 | 0.64435273 |
91 | Amoebiasis_Homo sapiens_hsa05146 | 0.64101173 |
92 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.61123829 |
93 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.60535951 |
94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.60157070 |
95 | Cell cycle_Homo sapiens_hsa04110 | 0.60055376 |
96 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.58776178 |
97 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.57383149 |
98 | Phagosome_Homo sapiens_hsa04145 | 0.55697863 |
99 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.55367765 |
100 | Lysine degradation_Homo sapiens_hsa00310 | 0.55206741 |
101 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.51500627 |
102 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.50932087 |
103 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50904377 |
104 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.49266426 |
105 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.49205880 |
106 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.48704457 |
107 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48138026 |
108 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.48021465 |
109 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.47765412 |
110 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47655323 |
111 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.46616516 |
112 | Sulfur relay system_Homo sapiens_hsa04122 | 0.46505764 |
113 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46353060 |
114 | Pathways in cancer_Homo sapiens_hsa05200 | 0.46240205 |
115 | Carbon metabolism_Homo sapiens_hsa01200 | 0.46065623 |
116 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.45968530 |
117 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.45301223 |
118 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44337302 |
119 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.44235716 |
120 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43707182 |
121 | Colorectal cancer_Homo sapiens_hsa05210 | 0.43678789 |
122 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.42567608 |
123 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42555000 |
124 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.41611501 |
125 | Bladder cancer_Homo sapiens_hsa05219 | 0.41012167 |
126 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40963530 |
127 | Galactose metabolism_Homo sapiens_hsa00052 | 0.40766714 |
128 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.40326394 |
129 | Prion diseases_Homo sapiens_hsa05020 | 0.38247996 |
130 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.37339518 |
131 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.34844694 |
132 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.34259147 |