PPP1R14B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)5.98405405
2translational termination (GO:0006415)5.80199034
3translational elongation (GO:0006414)5.14378598
4ribosomal small subunit assembly (GO:0000028)5.04687877
5nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.86541294
6translational initiation (GO:0006413)4.78690971
7ribosomal small subunit biogenesis (GO:0042274)4.69582371
8maturation of SSU-rRNA (GO:0030490)4.68485906
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.65182634
10protein targeting to ER (GO:0045047)4.53643300
11cellular protein complex disassembly (GO:0043624)4.51140352
12viral life cycle (GO:0019058)4.49547248
13cotranslational protein targeting to membrane (GO:0006613)4.47750287
14negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.39546888
15establishment of protein localization to endoplasmic reticulum (GO:0072599)4.32942005
16ribosomal large subunit biogenesis (GO:0042273)4.25654518
17regulation of mammary gland epithelial cell proliferation (GO:0033599)4.18704040
18protein complex disassembly (GO:0043241)4.17852867
19protein localization to endoplasmic reticulum (GO:0070972)4.16025016
20formation of translation preinitiation complex (GO:0001731)4.14167707
21nucleobase-containing small molecule interconversion (GO:0015949)4.12509597
22Golgi transport vesicle coating (GO:0048200)4.10567676
23COPI coating of Golgi vesicle (GO:0048205)4.10567676
24DNA unwinding involved in DNA replication (GO:0006268)4.05643320
25protein maturation by protein folding (GO:0022417)4.01794141
26protein retention in ER lumen (GO:0006621)3.93508012
27macromolecular complex disassembly (GO:0032984)3.86937383
28heterochromatin organization (GO:0070828)3.83597316
29proline biosynthetic process (GO:0006561)3.83126344
30protein localization to kinetochore (GO:0034501)3.82790721
31maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.79489680
32folic acid-containing compound biosynthetic process (GO:0009396)3.70821913
33regulation of protein heterodimerization activity (GO:0043497)3.53743504
34negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.53051657
35nuclear-transcribed mRNA catabolic process (GO:0000956)3.53027725
36mitotic chromosome condensation (GO:0007076)3.49262722
37regulation of translational termination (GO:0006449)3.47240639
38regulation of translational fidelity (GO:0006450)3.45165110
39nuclear envelope reassembly (GO:0031468)3.43730754
40mitotic nuclear envelope reassembly (GO:0007084)3.43730754
41negative regulation of RNA splicing (GO:0033119)3.43181108
42protein localization to endosome (GO:0036010)3.36714274
43peptidyl-arginine omega-N-methylation (GO:0035247)3.36037755
44ribonucleoprotein complex biogenesis (GO:0022613)3.35014861
45mRNA catabolic process (GO:0006402)3.34781685
46mitotic nuclear envelope disassembly (GO:0007077)3.34081689
47paraxial mesoderm development (GO:0048339)3.29127312
48negative regulation of cell size (GO:0045792)3.28498761
49protein localization to chromosome, centromeric region (GO:0071459)3.27655724
50RNA catabolic process (GO:0006401)3.26598066
51regulation of early endosome to late endosome transport (GO:2000641)3.22391232
52hemidesmosome assembly (GO:0031581)3.20399414
53regulation of gene silencing by RNA (GO:0060966)3.16412602
54regulation of posttranscriptional gene silencing (GO:0060147)3.16412602
55regulation of gene silencing by miRNA (GO:0060964)3.16412602
56DNA strand elongation involved in DNA replication (GO:0006271)3.15251595
57maternal placenta development (GO:0001893)3.14083224
58DNA replication-dependent nucleosome assembly (GO:0006335)3.13660251
59DNA replication-dependent nucleosome organization (GO:0034723)3.13660251
60cell-substrate adherens junction assembly (GO:0007045)3.12971120
61focal adhesion assembly (GO:0048041)3.12971120
62nuclear envelope disassembly (GO:0051081)3.11423950
63membrane disassembly (GO:0030397)3.11423950
64pentose-phosphate shunt (GO:0006098)3.11015783
65protein complex localization (GO:0031503)3.10805285
66adherens junction assembly (GO:0034333)3.10724442
67regulation of hippo signaling (GO:0035330)3.10110166
68positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.07560986
69protein targeting to membrane (GO:0006612)3.06262323
70GDP-mannose metabolic process (GO:0019673)3.05560254
71translation (GO:0006412)3.04865983
72establishment of integrated proviral latency (GO:0075713)3.01808971
73cell-substrate junction assembly (GO:0007044)3.01782965
74negative regulation of mRNA processing (GO:0050686)2.99009970
75mRNA stabilization (GO:0048255)2.98076608
76RNA stabilization (GO:0043489)2.98076608
77DNA strand elongation (GO:0022616)2.94671844
78glucose catabolic process (GO:0006007)2.92471442
79nuclear pore organization (GO:0006999)2.91132657
80DNA replication initiation (GO:0006270)2.89990249
813-UTR-mediated mRNA stabilization (GO:0070935)2.88912720
82cellular protein complex localization (GO:0034629)2.88871537
83rRNA transcription (GO:0009303)2.88115157
84peptidyl-arginine N-methylation (GO:0035246)2.87916142
85peptidyl-arginine methylation (GO:0018216)2.87916142
86IMP biosynthetic process (GO:0006188)2.87227451
87ncRNA 3-end processing (GO:0043628)2.86379100
88retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.85173563
89mitotic sister chromatid segregation (GO:0000070)2.84399316
90sister chromatid segregation (GO:0000819)2.82641408
91negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.82527463
92regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.82089453
93mitochondrial fusion (GO:0008053)2.79371137
94chromatin assembly (GO:0031497)2.78919862
95mitotic G1 DNA damage checkpoint (GO:0031571)2.78878563
96histone arginine methylation (GO:0034969)2.78789238
97UV protection (GO:0009650)2.77432009
98negative regulation of mRNA metabolic process (GO:1903312)2.76492859
99dosage compensation (GO:0007549)2.74407476
100nuclear pore complex assembly (GO:0051292)2.73928852
101rRNA processing (GO:0006364)2.73638913
102spliceosomal snRNP assembly (GO:0000387)2.71129361
103regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.70706373
104establishment of apical/basal cell polarity (GO:0035089)2.70631658
105telomere maintenance via semi-conservative replication (GO:0032201)2.70445148
106viral mRNA export from host cell nucleus (GO:0046784)2.70443297
107activation of Rac GTPase activity (GO:0032863)2.69766828
108pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.69681211
109T cell apoptotic process (GO:0070231)2.68583625
110NADPH regeneration (GO:0006740)2.67781626
111pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.66525324
112spliceosomal tri-snRNP complex assembly (GO:0000244)2.65922904
113apoptotic process involved in morphogenesis (GO:0060561)2.65472290
114rRNA metabolic process (GO:0016072)2.65437610
115regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.64263948
116dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.63455995
117epithelial cell-cell adhesion (GO:0090136)2.62081500
118pinocytosis (GO:0006907)2.61837514
119DNA deamination (GO:0045006)2.61627487
120DNA duplex unwinding (GO:0032508)2.61546831
121guanosine-containing compound biosynthetic process (GO:1901070)2.61437938
122mRNA splicing, via spliceosome (GO:0000398)2.61350008
123RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.61350008
124deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.61247412
125UTP biosynthetic process (GO:0006228)2.59295844
126termination of RNA polymerase II transcription (GO:0006369)2.59291682
127RNA splicing, via transesterification reactions (GO:0000375)2.59284003
128ribosome biogenesis (GO:0042254)2.58589165
129skin morphogenesis (GO:0043589)2.58407462
130regulation of glucose import in response to insulin stimulus (GO:2001273)2.58191030
131nuclear envelope organization (GO:0006998)2.58179883
132DNA geometric change (GO:0032392)2.58151641
133establishment of viral latency (GO:0019043)2.57744179
134DNA replication checkpoint (GO:0000076)2.56729693
135polarized epithelial cell differentiation (GO:0030859)2.56341847
136mitotic metaphase plate congression (GO:0007080)2.55325782
137positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.53964971
138pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.52875764
139positive regulation of chromosome segregation (GO:0051984)2.51968742
140regulation of apoptotic process involved in morphogenesis (GO:1902337)2.51731721
141barbed-end actin filament capping (GO:0051016)2.50444362
142IMP metabolic process (GO:0046040)2.49321491
143pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.48627893
144regulation of SMAD protein import into nucleus (GO:0060390)2.46341847
145protein localization to microtubule (GO:0035372)2.45653585
146ribosome assembly (GO:0042255)2.45483586
147desmosome organization (GO:0002934)2.44023144
148positive regulation of SMAD protein import into nucleus (GO:0060391)2.39337578
149regulation of translational elongation (GO:0006448)2.39252911
150mitotic G1/S transition checkpoint (GO:0044819)2.38886152
151regulation of sister chromatid cohesion (GO:0007063)2.37799053
152regulation of chromatin binding (GO:0035561)2.37772229
153vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.36960962
154peptidyl-proline hydroxylation (GO:0019511)2.36607835
155regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.36601201
156regulation of stem cell maintenance (GO:2000036)2.35846482
157spliceosomal complex assembly (GO:0000245)2.35570899
158chromatin assembly or disassembly (GO:0006333)2.35026283
159positive regulation of blood vessel endothelial cell migration (GO:0043536)2.34592172
160basement membrane organization (GO:0071711)2.34110652
161planar cell polarity pathway involved in neural tube closure (GO:0090179)2.33198352
162regulation of cell aging (GO:0090342)2.33074573

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.16820029
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.12329168
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.94245909
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.72759052
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.06939321
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.02515412
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.69107745
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.60961307
9MYC_22102868_ChIP-Seq_BL_Human2.53281140
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.40360171
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.36130064
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.29905211
13XRN2_22483619_ChIP-Seq_HELA_Human2.26818678
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.96271969
15VDR_21846776_ChIP-Seq_THP-1_Human1.95699511
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.94094071
17NELFA_20434984_ChIP-Seq_ESCs_Mouse1.93081639
18ETS1_20019798_ChIP-Seq_JURKAT_Human1.92308068
19* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.90921365
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.89067843
21CREB1_15753290_ChIP-ChIP_HEK293T_Human1.77062016
22NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.75835226
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.73398494
24DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.65743896
25EST1_17652178_ChIP-ChIP_JURKAT_Human1.64091879
26DCP1A_22483619_ChIP-Seq_HELA_Human1.60641854
27TTF2_22483619_ChIP-Seq_HELA_Human1.59649187
28TET1_21451524_ChIP-Seq_MESCs_Mouse1.59338609
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.58837012
30ZNF263_19887448_ChIP-Seq_K562_Human1.58804055
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56280986
32ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56190900
33* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.54837320
34SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.54109423
35ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.53827266
36* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53480772
37STAT3_1855785_ChIP-Seq_MESCs_Mouse1.53075014
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.52757878
39* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.51186956
40POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.50651692
41* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50538397
42MYCN_18555785_ChIP-Seq_MESCs_Mouse1.48067043
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.45826784
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.45298380
45* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45167914
46AR_21909140_ChIP-Seq_LNCAP_Human1.44419939
47JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.44410448
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44313813
49* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.42482915
50GABP_17652178_ChIP-ChIP_JURKAT_Human1.41487887
51* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.41080832
52* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.37215584
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.36299182
54* GABP_19822575_ChIP-Seq_HepG2_Human1.36121006
55CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.35487878
56THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35337209
57TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.33651299
58ATF3_27146783_Chip-Seq_COLON_Human1.31658592
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.31508784
60KDM5A_27292631_Chip-Seq_BREAST_Human1.31115133
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.30806979
62RARG_19884340_ChIP-ChIP_MEFs_Mouse1.30759826
63VDR_23849224_ChIP-Seq_CD4+_Human1.28884560
64CIITA_25753668_ChIP-Seq_RAJI_Human1.28419007
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28205259
66CLOCK_20551151_ChIP-Seq_293T_Human1.27448017
67ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.23972544
68KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.23242629
69TCF7_22412390_ChIP-Seq_EML_Mouse1.21598730
70TCF3_18692474_ChIP-Seq_MEFs_Mouse1.21332684
71SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.20435129
72TP53_22127205_ChIP-Seq_IMR90_Human1.20272077
73KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.20206564
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.19807023
75THAP11_20581084_ChIP-Seq_MESCs_Mouse1.19797678
76FOXP3_21729870_ChIP-Seq_TREG_Human1.19217388
77P68_20966046_ChIP-Seq_HELA_Human1.19165544
78ERG_21242973_ChIP-ChIP_JURKAT_Human1.17338781
79* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.17165650
80* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17164307
81KDM2B_26808549_Chip-Seq_DND41_Human1.16349970
82* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.16234461
83TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15386264
84* SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.14561162
85ESR1_15608294_ChIP-ChIP_MCF-7_Human1.14106063
86SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13653603
87* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.13484258
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.13311778
89* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.11325306
90UTX_26944678_Chip-Seq_JUKART_Human1.10704236
91* RACK7_27058665_Chip-Seq_MCF-7_Human1.10515649
92CTCF_18555785_ChIP-Seq_MESCs_Mouse1.10335443
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.09964620
94* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08355247
95UBF1/2_26484160_Chip-Seq_HMECs_Human1.07922898
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07778386
97TFEB_21752829_ChIP-Seq_HELA_Human1.07633312
98ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.06998361
99KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.06803734
100KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.06288127
101KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.06288127
102KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.06288127
103* KDM2B_26808549_Chip-Seq_K562_Human1.05165403
104* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.05081363
105NANOG_21062744_ChIP-ChIP_HESCs_Human1.04519106
106CHD1_26751641_Chip-Seq_LNCaP_Human1.03831934
107OCT4_18692474_ChIP-Seq_MEFs_Mouse1.02963241
108* LXR_22292898_ChIP-Seq_THP-1_Human1.02807560
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02305517
110ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01926735
111KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01889701
112NCOR1_26117541_ChIP-Seq_K562_Human1.00195530
113* MAF_26560356_Chip-Seq_TH1_Human1.00123604
114YY1_21170310_ChIP-Seq_MESCs_Mouse0.99168365
115NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.99062380
116* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98840406
117* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.98419469
118KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98100729
119FOXP1_21924763_ChIP-Seq_HESCs_Human0.98043581
120SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.97725248
121* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97423550
122POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97264758
123* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.97162228
124CREB1_26743006_Chip-Seq_LNCaP_Human0.97013691
125CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.96996584
126EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96685428
127CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.96619898
128SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.96203407
129* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96097108
130NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95593834
131SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94352381
132* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.94349312

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.71060294
2MP0010030_abnormal_orbit_morphology3.23736265
3MP0010352_gastrointestinal_tract_polyps2.97824822
4MP0003693_abnormal_embryo_hatching2.90402346
5MP0005451_abnormal_body_composition2.89828553
6MP0004957_abnormal_blastocyst_morpholog2.77711240
7MP0003111_abnormal_nucleus_morphology2.63395380
8MP0004858_abnormal_nervous_system2.49493681
9MP0010234_abnormal_vibrissa_follicle2.44115313
10MP0003077_abnormal_cell_cycle2.33915549
11MP0005076_abnormal_cell_differentiation2.30978593
12MP0008438_abnormal_cutaneous_collagen2.19417295
13MP0010094_abnormal_chromosome_stability2.12455457
14MP0000537_abnormal_urethra_morphology2.00883079
15MP0000733_abnormal_muscle_development1.95953745
16MP0009053_abnormal_anal_canal1.95749836
17MP0008932_abnormal_embryonic_tissue1.87574638
18MP0001730_embryonic_growth_arrest1.84966629
19MP0008007_abnormal_cellular_replicative1.81589585
20MP0000350_abnormal_cell_proliferation1.78824560
21MP0000678_abnormal_parathyroid_gland1.77184205
22MP0004197_abnormal_fetal_growth/weight/1.76595985
23MP0009379_abnormal_foot_pigmentation1.71728699
24MP0000750_abnormal_muscle_regeneration1.62211703
25MP0009278_abnormal_bone_marrow1.59539766
26MP0003566_abnormal_cell_adhesion1.57287322
27MP0000003_abnormal_adipose_tissue1.55330910
28MP0000490_abnormal_crypts_of1.53737492
29MP0002085_abnormal_embryonic_tissue1.53507600
30MP0001697_abnormal_embryo_size1.52139473
31MP0002084_abnormal_developmental_patter1.50490814
32MP0003123_paternal_imprinting1.50418411
33MP0001672_abnormal_embryogenesis/_devel1.46707202
34MP0005380_embryogenesis_phenotype1.46707202
35MP0010307_abnormal_tumor_latency1.44379104
36MP0005058_abnormal_lysosome_morphology1.41593349
37MP0000428_abnormal_craniofacial_morphol1.41029609
38MP0005257_abnormal_intraocular_pressure1.39729126
39MP0001849_ear_inflammation1.38668261
40MP0005623_abnormal_meninges_morphology1.38481430
41MP0005275_abnormal_skin_tensile1.37895536
42MP0005023_abnormal_wound_healing1.37663621
43MP0002877_abnormal_melanocyte_morpholog1.37488422
44MP0002653_abnormal_ependyma_morphology1.37370219
45MP0003984_embryonic_growth_retardation1.36906947
46MP0002088_abnormal_embryonic_growth/wei1.36089456
47MP0002086_abnormal_extraembryonic_tissu1.35848298
48MP0002080_prenatal_lethality1.34740704
49MP0000751_myopathy1.33582638
50MP0003567_abnormal_fetal_cardiomyocyte1.33255668
51MP0008057_abnormal_DNA_replication1.31498740
52MP0009840_abnormal_foam_cell1.31070057
53MP0000759_abnormal_skeletal_muscle1.27965159
54MP0002282_abnormal_trachea_morphology1.27537552
55MP0002089_abnormal_postnatal_growth/wei1.25401675
56MP0001293_anophthalmia1.25111238
57MP0002249_abnormal_larynx_morphology1.25108608
58MP0001661_extended_life_span1.21766037
59MP0000049_abnormal_middle_ear1.21103678
60MP0005375_adipose_tissue_phenotype1.19759583
61MP0004808_abnormal_hematopoietic_stem1.18224245
62MP0003385_abnormal_body_wall1.17411966
63MP0002932_abnormal_joint_morphology1.17135720
64MP0003942_abnormal_urinary_system1.16963629
65MP0006054_spinal_hemorrhage1.16960414
66MP0000858_altered_metastatic_potential1.15450778
67MP0003119_abnormal_digestive_system1.15316099
68MP0002111_abnormal_tail_morphology1.14687808
69MP0004185_abnormal_adipocyte_glucose1.12776823
70MP0005501_abnormal_skin_physiology1.12463186
71MP0002060_abnormal_skin_morphology1.10809680
72MP0001348_abnormal_lacrimal_gland1.10269480
73MP0001216_abnormal_epidermal_layer1.10093835
74MP0003941_abnormal_skin_development1.09979688
75MP0002697_abnormal_eye_size1.09861570
76MP0005666_abnormal_adipose_tissue1.09476352
77MP0002396_abnormal_hematopoietic_system1.09251042
78MP0003115_abnormal_respiratory_system1.08885633
79MP0002092_abnormal_eye_morphology1.08293183
80MP0000747_muscle_weakness1.08197027
81MP0009333_abnormal_splenocyte_physiolog1.07850052
82MP0000579_abnormal_nail_morphology1.06557227
83MP0000749_muscle_degeneration1.02548177
84MP0003755_abnormal_palate_morphology1.02360143
85MP0002019_abnormal_tumor_incidence1.01936908
86MP0005508_abnormal_skeleton_morphology1.00302516
87MP0004087_abnormal_muscle_fiber1.00171016
88MP0008260_abnormal_autophagy0.99841433
89MP0009250_abnormal_appendicular_skeleto0.99255827
90MP0008058_abnormal_DNA_repair0.98103683
91MP0004272_abnormal_basement_membrane0.97508425
92MP0001915_intracranial_hemorrhage0.96618056
93MP0000313_abnormal_cell_death0.96065512
94MP0003453_abnormal_keratinocyte_physiol0.95349133
95MP0000432_abnormal_head_morphology0.95185756
96MP0003935_abnormal_craniofacial_develop0.94730214
97MP0002234_abnormal_pharynx_morphology0.94706048
98MP0004233_abnormal_muscle_weight0.93247056
99MP0000013_abnormal_adipose_tissue0.91288126
100MP0003937_abnormal_limbs/digits/tail_de0.91255232
101MP0000358_abnormal_cell_content/0.90862500
102MP0010771_integument_phenotype0.90653847
103MP0003279_aneurysm0.90552288
104MP0003950_abnormal_plasma_membrane0.89974895
105MP0005621_abnormal_cell_physiology0.87904221
106MP0004510_myositis0.87699172
107MP0002796_impaired_skin_barrier0.86108470
108MP0000762_abnormal_tongue_morphology0.84044265
109MP0002163_abnormal_gland_morphology0.83943023
110MP0003091_abnormal_cell_migration0.83765928
111MP0010368_abnormal_lymphatic_system0.83649666
112MP0002925_abnormal_cardiovascular_devel0.83590341
113MP0005397_hematopoietic_system_phenotyp0.83561137
114MP0001545_abnormal_hematopoietic_system0.83561137
115MP0003315_abnormal_perineum_morphology0.83436199
116MP0002116_abnormal_craniofacial_bone0.82490226
117MP0000462_abnormal_digestive_system0.82015684
118MP0003448_altered_tumor_morphology0.81960972
119MP0005503_abnormal_tendon_morphology0.81744428
120MP0003300_gastrointestinal_ulcer0.81656231
121MP0005197_abnormal_uvea_morphology0.81443415
122MP0009384_cardiac_valve_regurgitation0.80472163
123MP0000534_abnormal_ureter_morphology0.80461855
124MP0003786_premature_aging0.79912001
125MP0002114_abnormal_axial_skeleton0.79675344
126MP0000477_abnormal_intestine_morphology0.79476430
127MP0000467_abnormal_esophagus_morphology0.78732734
128MP0005330_cardiomyopathy0.77910020
129MP0008789_abnormal_olfactory_epithelium0.77751590
130MP0001286_abnormal_eye_development0.77496961
131MP0000703_abnormal_thymus_morphology0.77311754
132MP0002896_abnormal_bone_mineralization0.76268753
133MP0003806_abnormal_nucleotide_metabolis0.76145698
134MP0003303_peritoneal_inflammation0.76090056
135MP0000767_abnormal_smooth_muscle0.75923821
136MP0001243_abnormal_dermal_layer0.75841790
137MP0005384_cellular_phenotype0.75457277
138MP0000377_abnormal_hair_follicle0.75048404
139MP0009672_abnormal_birth_weight0.74050663

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.03920654
2Protrusio acetabuli (HP:0003179)3.79404596
3Reticulocytopenia (HP:0001896)3.68860888
4Premature rupture of membranes (HP:0001788)3.45729372
5Abnormal number of erythroid precursors (HP:0012131)3.30544043
6Selective tooth agenesis (HP:0001592)3.21700000
7Vertebral compression fractures (HP:0002953)3.12124130
8Trismus (HP:0000211)3.00726788
9Distal lower limb amyotrophy (HP:0008944)2.93326607
10Shallow orbits (HP:0000586)2.85879410
11Distal lower limb muscle weakness (HP:0009053)2.72892762
12Increased density of long bones (HP:0006392)2.69303577
13Genu recurvatum (HP:0002816)2.66803946
14Short nail (HP:0001799)2.66074168
15Pallor (HP:0000980)2.63407711
16Progressive muscle weakness (HP:0003323)2.59253997
17Generalized amyotrophy (HP:0003700)2.55573736
18Ankle contracture (HP:0006466)2.53587566
19Insomnia (HP:0100785)2.50730290
20Macrocytic anemia (HP:0001972)2.47547364
21Abnormality of the calcaneus (HP:0008364)2.44251585
22Distal upper limb amyotrophy (HP:0007149)2.38428316
23Upper limb amyotrophy (HP:0009129)2.38428316
24Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.37900719
25Short 4th metacarpal (HP:0010044)2.37900719
26Abnormality of the distal phalanges of the toes (HP:0010182)2.34196183
27Long palpebral fissure (HP:0000637)2.32546873
28Calcaneovalgus deformity (HP:0001848)2.30119313
29Rough bone trabeculation (HP:0100670)2.29179693
30Hyperacusis (HP:0010780)2.29151228
31Multiple enchondromatosis (HP:0005701)2.28831260
32Cerebral aneurysm (HP:0004944)2.28830849
33Colon cancer (HP:0003003)2.27437318
34Difficulty climbing stairs (HP:0003551)2.25954981
35Renal duplication (HP:0000075)2.25435637
36Increased connective tissue (HP:0009025)2.19991679
37Broad distal phalanx of finger (HP:0009836)2.18533093
38Abnormal hemoglobin (HP:0011902)2.18507597
39Angiofibromas (HP:0010615)2.17672401
40Adenoma sebaceum (HP:0009720)2.17672401
41Disproportionate tall stature (HP:0001519)2.17635423
42Reduced subcutaneous adipose tissue (HP:0003758)2.17635088
43Achilles tendon contracture (HP:0001771)2.16056905
44Centrally nucleated skeletal muscle fibers (HP:0003687)2.15734384
45Missing ribs (HP:0000921)2.14306875
46Rectal prolapse (HP:0002035)2.13103737
47Ulnar bowing (HP:0003031)2.12880121
48Atresia of the external auditory canal (HP:0000413)2.12204937
49Spinal cord compression (HP:0002176)2.10667527
50Ependymoma (HP:0002888)2.10555937
51Natal tooth (HP:0000695)2.10350678
52Deformed tarsal bones (HP:0008119)2.09866227
53Asymmetry of the thorax (HP:0001555)2.09819756
54Basal cell carcinoma (HP:0002671)2.07240149
55Osteolytic defects of the hand bones (HP:0009699)2.05069373
56Osteolytic defects of the phalanges of the hand (HP:0009771)2.05069373
57Mitral regurgitation (HP:0001653)2.04777277
58Deviation of the hallux (HP:0010051)2.03819345
59Abnormality of dentin (HP:0010299)2.02580513
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02327170
61Myopathic facies (HP:0002058)2.02222757
62Hallux valgus (HP:0001822)2.02073126
63Deviation of the thumb (HP:0009603)2.01022492
64Abnormalities of placenta or umbilical cord (HP:0001194)1.99390859
65Type 1 muscle fiber predominance (HP:0003803)1.99296469
66Rib fusion (HP:0000902)1.98441750
67Aplasia/Hypoplasia of the patella (HP:0006498)1.97992660
68Lower limb amyotrophy (HP:0007210)1.97593308
69Patellar aplasia (HP:0006443)1.97394103
70Hyperparathyroidism (HP:0000843)1.96462209
71Back pain (HP:0003418)1.96354694
72Biconcave vertebral bodies (HP:0004586)1.96233483
73Pterygium (HP:0001059)1.93204868
74Overriding aorta (HP:0002623)1.92443832
75Wrist flexion contracture (HP:0001239)1.92286018
76Bladder diverticulum (HP:0000015)1.92159380
77Entropion (HP:0000621)1.91555891
78Patellar dislocation (HP:0002999)1.91322583
79Abnormality of the 4th metacarpal (HP:0010012)1.90910364
80Thin bony cortex (HP:0002753)1.89726440
81Elfin facies (HP:0004428)1.89356789
82Broad face (HP:0000283)1.89239857
83Proximal placement of thumb (HP:0009623)1.88217324
84Slender long bone (HP:0003100)1.85554946
85Thin ribs (HP:0000883)1.85547169
86Wormian bones (HP:0002645)1.84664147
87Atrophic scars (HP:0001075)1.83228332
88Mitral valve prolapse (HP:0001634)1.83001779
89Pelvic girdle muscle weakness (HP:0003749)1.82218559
90Abnormality of the anterior horn cell (HP:0006802)1.81975996
91Degeneration of anterior horn cells (HP:0002398)1.81975996
92Soft skin (HP:0000977)1.81736731
93Premature skin wrinkling (HP:0100678)1.79591955
94Abnormality of the Achilles tendon (HP:0005109)1.79105814
95Breech presentation (HP:0001623)1.78648451
96Congenital glaucoma (HP:0001087)1.78485310
97Ragged-red muscle fibers (HP:0003200)1.77732054
98Absent thumb (HP:0009777)1.77413468
99Bulbar palsy (HP:0001283)1.76625580
100Increased nuchal translucency (HP:0010880)1.76557083
101Bicuspid aortic valve (HP:0001647)1.76487876
102Abnormal trabecular bone morphology (HP:0100671)1.75613471
103Increased variability in muscle fiber diameter (HP:0003557)1.75596828
104Vertebral fusion (HP:0002948)1.75389492
105Abnormality of the tricuspid valve (HP:0001702)1.75345757
106Round ear (HP:0100830)1.74358958
107Aplasia/hypoplasia of the humerus (HP:0006507)1.74305150
108Fragile skin (HP:0001030)1.73987287
109Abnormality of skeletal muscle fiber size (HP:0012084)1.73180695
110Stridor (HP:0010307)1.72713600
111Fused cervical vertebrae (HP:0002949)1.72341292
112Astrocytoma (HP:0009592)1.72212703
113Abnormality of the astrocytes (HP:0100707)1.72212703
114Down-sloping shoulders (HP:0200021)1.72138092
115Rhabdomyosarcoma (HP:0002859)1.71805166
116Neonatal short-limb short stature (HP:0008921)1.71370606
117Bowel diverticulosis (HP:0005222)1.70853273
118Peritonitis (HP:0002586)1.70017183
119Dilatation of the ascending aorta (HP:0005111)1.69988938
120Syringomyelia (HP:0003396)1.69942871
121Spinal cord lesions (HP:0100561)1.69942871
122Fibroma (HP:0010614)1.69465139
123Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.69404761
124Vertebral hypoplasia (HP:0008417)1.69404761
125Cervical subluxation (HP:0003308)1.69343839
126Concave nail (HP:0001598)1.69328269
127Abnormal number of incisors (HP:0011064)1.68136417
128Flat acetabular roof (HP:0003180)1.68118946
129Spinal rigidity (HP:0003306)1.67669211
130Ankyloglossia (HP:0010296)1.66313277
131Advanced eruption of teeth (HP:0006288)1.66019347
132Abnormality of oral frenula (HP:0000190)1.65317756
133Hypercalcemia (HP:0003072)1.65049286
134Abnormality of the umbilical cord (HP:0010881)1.64657783
135Short clavicles (HP:0000894)1.64418991
136Glossoptosis (HP:0000162)1.64097649
137Malignant gastrointestinal tract tumors (HP:0006749)1.63764591
138Gastrointestinal carcinoma (HP:0002672)1.63764591
139Abnormal ossification of hand bones (HP:0005921)1.63705320
140Ulnar deviation of the wrist (HP:0003049)1.63629814
141Testicular atrophy (HP:0000029)1.63603252
142Elbow flexion contracture (HP:0002987)1.63145205
143Neoplasm of the pancreas (HP:0002894)1.62997964
144Abnormal umbilical cord blood vessels (HP:0011403)1.62855376
145Single umbilical artery (HP:0001195)1.62855376
146Abnormality of the fetal cardiovascular system (HP:0010948)1.62855376
147Thrombocytosis (HP:0001894)1.62248365
148Radial bowing (HP:0002986)1.62223994
149Abnormality of carpal bone ossification (HP:0006257)1.62159583
150Blue sclerae (HP:0000592)1.62138781
151Hand muscle atrophy (HP:0009130)1.62094524
152Fibrous tissue neoplasm (HP:0012316)1.61800251
153Coronal craniosynostosis (HP:0004440)1.60541404
154Mildly elevated creatine phosphokinase (HP:0008180)1.60068996
155Skin tags (HP:0010609)1.59244371
156Preauricular skin tag (HP:0000384)1.58742245
157Short palpebral fissure (HP:0012745)1.58182680
158Bowed forearm bones (HP:0003956)1.57579854
159Bowing of the arm (HP:0006488)1.57579854
160Cutaneous melanoma (HP:0012056)1.57291354
161Breast hypoplasia (HP:0003187)1.56744081
162Broad thumb (HP:0011304)1.56164696
163Overlapping toe (HP:0001845)1.55617454

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.13447226
2IRAK34.10462594
3EEF2K3.67962167
4MAP3K103.41647902
5PKN23.32533906
6TLK13.23169435
7SMG13.23122054
8NME22.63497355
9BUB12.30290226
10ARAF2.18922496
11CDC72.16767040
12NEK22.13214724
13RPS6KB22.11879963
14MST1R2.02337095
15VRK22.00876180
16LRRK21.91708912
17PRPF4B1.89746792
18TTN1.80919429
19CDK121.79602455
20EPHA21.76426151
21PAK41.62999182
22RPS6KA41.59139430
23BMX1.57156644
24ICK1.56922867
25TESK21.54716056
26WEE11.53025264
27EPHB21.49690783
28PDGFRA1.47911730
29CDK71.45674688
30DDR21.42911024
31LATS21.41963268
32ERN11.39542008
33BRAF1.38921962
34PIM21.34368339
35TESK11.28373065
36SCYL21.28355888
37MAP3K81.27114999
38LATS11.25171252
39STK101.25168197
40PTK61.24646280
41CDK41.23573841
42EIF2AK11.22661423
43MET1.20567490
44DYRK31.19621259
45LMTK21.19336906
46MAPKAPK31.18525473
47MUSK1.17836333
48MAP3K111.16463683
49TGFBR11.15465726
50PAK21.13254379
51PASK1.12807282
52TTK1.12202956
53AURKB1.11582126
54CDK61.10880639
55ABL21.10461940
56NEK11.07486890
57IRAK21.06957160
58NTRK11.05708845
59SRPK11.05119935
60PRKD31.04744179
61PLK11.02087026
62MTOR1.01207088
63PBK1.00346045
64ALK1.00065888
65MKNK10.97960758
66ERBB40.85551029
67AURKA0.85188644
68DYRK1B0.84985677
69PIM10.84955998
70PAK10.83735841
71STK30.81859265
72MKNK20.80296950
73CHEK20.76848044
74MOS0.75643115
75ATR0.75195632
76MAP2K30.70934491
77CHEK10.70164974
78STK160.68300158
79AKT20.66781437
80LIMK10.66735904
81PRKD20.63767884
82* ILK0.62535541
83PRKG20.62440217
84TYRO30.61481151
85RPS6KA20.61184941
86FLT30.60180585
87CDK20.60056511
88CDK80.56419987
89FGFR10.55553480
90STK40.55494162
91RPS6KA10.54696015
92MAP4K10.52602316
93MAP2K20.52142760
94BRSK20.50857874
95PTK20.50565362
96MAP3K90.50029438
97SIK10.49847015
98DAPK30.48424419
99RIPK10.46247932
100RPS6KL10.45978046
101RPS6KC10.45978046
102MAPKAPK20.45786334
103MAPK110.45644464
104TAOK20.44064680
105KDR0.43619305
106MAP3K30.43234567
107PRKCI0.42769171
108BRSK10.42494274
109ATM0.42446181
110TSSK60.42368330
111CDK11A0.42057314
112TAOK10.41909202
113GRK60.41819879
114ACVR1B0.40619169
115RPS6KA60.40102606
116IRAK40.39565811
117CSNK2A20.37258964
118DAPK10.36974597
119CAMK2G0.36914503
120CDK150.36327505
121TAF10.36134601
122DMPK0.36014021
123PDPK10.35577132
124PDGFRB0.34609715
125NEK90.34138396
126MELK0.33655351
127CDK90.33419834
128CDK180.31982567
129CDK10.31081500
130CSNK2A10.30465428

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.53474101
2DNA replication_Homo sapiens_hsa030303.44424423
3Spliceosome_Homo sapiens_hsa030402.91194583
4Mismatch repair_Homo sapiens_hsa034302.74777150
5RNA transport_Homo sapiens_hsa030132.64294233
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.46145371
7One carbon pool by folate_Homo sapiens_hsa006702.31633073
8Base excision repair_Homo sapiens_hsa034102.29364885
9Cell cycle_Homo sapiens_hsa041102.28040366
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.87574011
11Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.85811157
12Nucleotide excision repair_Homo sapiens_hsa034201.85550283
13mRNA surveillance pathway_Homo sapiens_hsa030151.81187723
14p53 signaling pathway_Homo sapiens_hsa041151.80767037
15Bladder cancer_Homo sapiens_hsa052191.70400068
16RNA polymerase_Homo sapiens_hsa030201.69469748
17Chronic myeloid leukemia_Homo sapiens_hsa052201.61050059
18Galactose metabolism_Homo sapiens_hsa000521.60676617
19Fructose and mannose metabolism_Homo sapiens_hsa000511.60316031
20Proteasome_Homo sapiens_hsa030501.57555252
21Homologous recombination_Homo sapiens_hsa034401.56974991
22Basal cell carcinoma_Homo sapiens_hsa052171.56830281
23Systemic lupus erythematosus_Homo sapiens_hsa053221.54910233
24Vitamin B6 metabolism_Homo sapiens_hsa007501.48846702
25MicroRNAs in cancer_Homo sapiens_hsa052061.48576053
26Small cell lung cancer_Homo sapiens_hsa052221.44836937
27Hippo signaling pathway_Homo sapiens_hsa043901.39471611
28Viral carcinogenesis_Homo sapiens_hsa052031.34672589
29Pyrimidine metabolism_Homo sapiens_hsa002401.33437880
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.31210028
31Notch signaling pathway_Homo sapiens_hsa043301.29054366
32Sulfur relay system_Homo sapiens_hsa041221.26293815
33HTLV-I infection_Homo sapiens_hsa051661.24854612
34Proteoglycans in cancer_Homo sapiens_hsa052051.23424861
35Prion diseases_Homo sapiens_hsa050201.21270649
36Hedgehog signaling pathway_Homo sapiens_hsa043401.20987255
37Thyroid cancer_Homo sapiens_hsa052161.20668994
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.17508554
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.15290810
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14736959
41RNA degradation_Homo sapiens_hsa030181.11787929
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.11465857
43Adherens junction_Homo sapiens_hsa045201.10999639
44Central carbon metabolism in cancer_Homo sapiens_hsa052301.07612590
45Acute myeloid leukemia_Homo sapiens_hsa052211.07014825
46Colorectal cancer_Homo sapiens_hsa052101.06845743
47Fanconi anemia pathway_Homo sapiens_hsa034601.04953646
48Viral myocarditis_Homo sapiens_hsa054160.98556295
49Folate biosynthesis_Homo sapiens_hsa007900.98478722
50Vibrio cholerae infection_Homo sapiens_hsa051100.98237164
51TGF-beta signaling pathway_Homo sapiens_hsa043500.98204558
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.96521962
53Other glycan degradation_Homo sapiens_hsa005110.95891235
54Epstein-Barr virus infection_Homo sapiens_hsa051690.95685358
55mTOR signaling pathway_Homo sapiens_hsa041500.95672465
56Endometrial cancer_Homo sapiens_hsa052130.95492853
57Focal adhesion_Homo sapiens_hsa045100.93859380
58Apoptosis_Homo sapiens_hsa042100.93375734
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90218721
60Non-small cell lung cancer_Homo sapiens_hsa052230.88725220
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88160217
62Shigellosis_Homo sapiens_hsa051310.88060643
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.87982160
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.86687814
65Biosynthesis of amino acids_Homo sapiens_hsa012300.82883159
66AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82688473
67Pancreatic cancer_Homo sapiens_hsa052120.82450409
68Herpes simplex infection_Homo sapiens_hsa051680.82315725
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.79492018
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.77088403
71Antigen processing and presentation_Homo sapiens_hsa046120.76903917
72Glutathione metabolism_Homo sapiens_hsa004800.75544301
73Hepatitis B_Homo sapiens_hsa051610.74910853
74Prostate cancer_Homo sapiens_hsa052150.74553230
75VEGF signaling pathway_Homo sapiens_hsa043700.74307137
76Melanoma_Homo sapiens_hsa052180.73887938
77Legionellosis_Homo sapiens_hsa051340.73659370
78ECM-receptor interaction_Homo sapiens_hsa045120.73627122
79Pathways in cancer_Homo sapiens_hsa052000.73327638
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72466189
81ErbB signaling pathway_Homo sapiens_hsa040120.70534783
82Salmonella infection_Homo sapiens_hsa051320.68712692
83HIF-1 signaling pathway_Homo sapiens_hsa040660.68406516
84Non-homologous end-joining_Homo sapiens_hsa034500.67867194
85Tight junction_Homo sapiens_hsa045300.67647463
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.66054403
87Glioma_Homo sapiens_hsa052140.65222791
88Pyruvate metabolism_Homo sapiens_hsa006200.64086775
89Alcoholism_Homo sapiens_hsa050340.63908295
90Wnt signaling pathway_Homo sapiens_hsa043100.62848097
91Basal transcription factors_Homo sapiens_hsa030220.62288643
92Pentose phosphate pathway_Homo sapiens_hsa000300.60732435
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.60724223
94Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59933374
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.58354965
96Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.57862849
97Oocyte meiosis_Homo sapiens_hsa041140.57568502
98Purine metabolism_Homo sapiens_hsa002300.57030259
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56686152
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.56650921
101Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.55848993
102PI3K-Akt signaling pathway_Homo sapiens_hsa041510.54914644
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.53880750
104Dilated cardiomyopathy_Homo sapiens_hsa054140.53540015
105Renal cell carcinoma_Homo sapiens_hsa052110.52019384
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51896679
107Sulfur metabolism_Homo sapiens_hsa009200.51781096
108Toxoplasmosis_Homo sapiens_hsa051450.51425415
109Arginine and proline metabolism_Homo sapiens_hsa003300.50764740
110Amoebiasis_Homo sapiens_hsa051460.49749587
111Selenocompound metabolism_Homo sapiens_hsa004500.48603907
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48093435
113Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46033509
114Endocytosis_Homo sapiens_hsa041440.44753969
115Measles_Homo sapiens_hsa051620.43384626
116N-Glycan biosynthesis_Homo sapiens_hsa005100.41807816
117Carbon metabolism_Homo sapiens_hsa012000.40891620
118Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40241655
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39623864
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.39498606
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38906784
122Insulin signaling pathway_Homo sapiens_hsa049100.38593119
123B cell receptor signaling pathway_Homo sapiens_hsa046620.37799269
124AMPK signaling pathway_Homo sapiens_hsa041520.37415820
125Prolactin signaling pathway_Homo sapiens_hsa049170.36730333
126FoxO signaling pathway_Homo sapiens_hsa040680.36563024
1272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36337627

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