

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of sequestering of triglyceride (GO:0010889) | 6.50726977 |
| 2 | regulation of somitogenesis (GO:0014807) | 6.02966389 |
| 3 | homocysteine metabolic process (GO:0050667) | 5.82182343 |
| 4 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 5.66934829 |
| 5 | regulation of plasminogen activation (GO:0010755) | 5.23066043 |
| 6 | viral mRNA export from host cell nucleus (GO:0046784) | 5.17083615 |
| 7 | regulation of skeletal muscle contraction (GO:0014819) | 5.11117992 |
| 8 | positive regulation of fatty acid oxidation (GO:0046321) | 5.06801167 |
| 9 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.91440195 |
| 10 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 4.87054951 |
| 11 | regulation of tight junction assembly (GO:2000810) | 4.82727924 |
| 12 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.76357826 |
| 13 | sarcomere organization (GO:0045214) | 4.74769489 |
| 14 | muscle filament sliding (GO:0030049) | 4.60889795 |
| 15 | actin-myosin filament sliding (GO:0033275) | 4.60889795 |
| 16 | desmosome organization (GO:0002934) | 4.60443124 |
| 17 | carnitine shuttle (GO:0006853) | 4.57654857 |
| 18 | negative regulation of DNA biosynthetic process (GO:2000279) | 4.46390843 |
| 19 | cardiac muscle contraction (GO:0060048) | 4.42068002 |
| 20 | white fat cell differentiation (GO:0050872) | 4.41740869 |
| 21 | cell migration involved in heart development (GO:0060973) | 4.38144556 |
| 22 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.36723917 |
| 23 | sulfur amino acid catabolic process (GO:0000098) | 4.24770086 |
| 24 | microtubule nucleation (GO:0007020) | 4.23094841 |
| 25 | cartilage morphogenesis (GO:0060536) | 4.21238150 |
| 26 | response to caffeine (GO:0031000) | 4.16640928 |
| 27 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.11747076 |
| 28 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 4.11524427 |
| 29 | fatty acid transmembrane transport (GO:1902001) | 4.10269335 |
| 30 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.06875923 |
| 31 | actin-mediated cell contraction (GO:0070252) | 4.04973394 |
| 32 | myofibril assembly (GO:0030239) | 4.02750780 |
| 33 | cardiac muscle hypertrophy (GO:0003300) | 3.98898270 |
| 34 | negative regulation of catenin import into nucleus (GO:0035414) | 3.87982588 |
| 35 | regulation of DNA damage checkpoint (GO:2000001) | 3.87933448 |
| 36 | adenosine metabolic process (GO:0046085) | 3.83781243 |
| 37 | striated muscle hypertrophy (GO:0014897) | 3.83146230 |
| 38 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.82621532 |
| 39 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.80781421 |
| 40 | cardiac myofibril assembly (GO:0055003) | 3.76179673 |
| 41 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.76096032 |
| 42 | dendritic spine morphogenesis (GO:0060997) | 3.73361814 |
| 43 | cysteine metabolic process (GO:0006534) | 3.72197065 |
| 44 | behavioral response to nicotine (GO:0035095) | 3.71498033 |
| 45 | prostate gland growth (GO:0060736) | 3.70053026 |
| 46 | positive regulation of heart rate (GO:0010460) | 3.69763804 |
| 47 | response to epinephrine (GO:0071871) | 3.68252677 |
| 48 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.67952470 |
| 49 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.67952470 |
| 50 | striated muscle contraction (GO:0006941) | 3.67030920 |
| 51 | response to inactivity (GO:0014854) | 3.64503362 |
| 52 | galactose metabolic process (GO:0006012) | 3.48685012 |
| 53 | purine nucleotide salvage (GO:0032261) | 3.44979830 |
| 54 | regulation of fatty acid oxidation (GO:0046320) | 3.44636384 |
| 55 | regulation of actin filament-based movement (GO:1903115) | 3.44249726 |
| 56 | cardiac muscle cell action potential (GO:0086001) | 3.38055531 |
| 57 | regulation of relaxation of muscle (GO:1901077) | 3.37642307 |
| 58 | muscle hypertrophy (GO:0014896) | 3.36301861 |
| 59 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.35640748 |
| 60 | carnitine transmembrane transport (GO:1902603) | 3.35321024 |
| 61 | otic vesicle formation (GO:0030916) | 3.32229675 |
| 62 | negative regulation of Ras GTPase activity (GO:0034261) | 3.29902843 |
| 63 | regulation of energy homeostasis (GO:2000505) | 3.28666677 |
| 64 | histone H4-K12 acetylation (GO:0043983) | 3.28622305 |
| 65 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.28309046 |
| 66 | positive regulation of fatty acid metabolic process (GO:0045923) | 3.25778426 |
| 67 | regulation of striated muscle contraction (GO:0006942) | 3.19096468 |
| 68 | relaxation of cardiac muscle (GO:0055119) | 3.16048535 |
| 69 | cAMP biosynthetic process (GO:0006171) | 3.15320153 |
| 70 | cardiac muscle adaptation (GO:0014887) | 3.14413797 |
| 71 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.14413797 |
| 72 | muscle hypertrophy in response to stress (GO:0003299) | 3.14413797 |
| 73 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.14362018 |
| 74 | regulation of heart rate (GO:0002027) | 3.13206536 |
| 75 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.11908907 |
| 76 | actomyosin structure organization (GO:0031032) | 3.11160944 |
| 77 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.10333799 |
| 78 | positive regulation of histone acetylation (GO:0035066) | 3.09844382 |
| 79 | response to muscle activity (GO:0014850) | 3.09728881 |
| 80 | adrenergic receptor signaling pathway (GO:0071875) | 3.06306122 |
| 81 | regulation of hippo signaling (GO:0035330) | 3.01780571 |
| 82 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.01691681 |
| 83 | carnitine transport (GO:0015879) | 3.01082313 |
| 84 | amino-acid betaine transport (GO:0015838) | 3.01082313 |
| 85 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.98448821 |
| 86 | regulation of membrane repolarization (GO:0060306) | 2.98200450 |
| 87 | cGMP-mediated signaling (GO:0019934) | 2.97657918 |
| 88 | cell communication by electrical coupling (GO:0010644) | 2.97378598 |
| 89 | regulation of cholesterol storage (GO:0010885) | 2.96372905 |
| 90 | cochlea development (GO:0090102) | 2.92265195 |
| 91 | muscle tissue morphogenesis (GO:0060415) | 2.91269648 |
| 92 | striated muscle adaptation (GO:0014888) | 2.89944249 |
| 93 | growth hormone secretion (GO:0030252) | 2.85422351 |
| 94 | lymphangiogenesis (GO:0001946) | 2.83335601 |
| 95 | inner ear receptor cell development (GO:0060119) | 2.83177877 |
| 96 | skeletal muscle adaptation (GO:0043501) | 2.82642804 |
| 97 | galactose catabolic process (GO:0019388) | 2.82574769 |
| 98 | creatine metabolic process (GO:0006600) | 2.82409845 |
| 99 | skeletal muscle contraction (GO:0003009) | 2.81781275 |
| 100 | primary amino compound metabolic process (GO:1901160) | 2.76844799 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 5.30510643 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.95238331 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.16762224 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.76917452 |
| 5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.98031880 |
| 6 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.68947135 |
| 7 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.63348983 |
| 8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.50554259 |
| 9 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.50554259 |
| 10 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.44178562 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.29501707 |
| 12 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.29458871 |
| 13 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.26435417 |
| 14 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.25938145 |
| 15 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.22221654 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.13565358 |
| 17 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.04138042 |
| 18 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.02327065 |
| 19 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.99641062 |
| 20 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.98279223 |
| 21 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.94796049 |
| 22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.91844814 |
| 23 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.84941129 |
| 24 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.77562038 |
| 25 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.77562038 |
| 26 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.77562038 |
| 27 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.71392152 |
| 28 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.70965125 |
| 29 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.70181099 |
| 30 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.69805739 |
| 31 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.66585606 |
| 32 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.61083951 |
| 33 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.57534577 |
| 34 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.53220122 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.52599659 |
| 36 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.50622469 |
| 37 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.50578950 |
| 38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.49894986 |
| 39 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48903748 |
| 40 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.48122301 |
| 41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.46000731 |
| 42 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.45464920 |
| 43 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.45369153 |
| 44 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.42709700 |
| 45 | RXR_22108803_ChIP-Seq_LS180_Human | 1.37699327 |
| 46 | TP53_16413492_ChIP-PET_HCT116_Human | 1.34264525 |
| 47 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.26980332 |
| 48 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.22583855 |
| 49 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.21333423 |
| 50 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.20695594 |
| 51 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.20620213 |
| 52 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.20313372 |
| 53 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.19068365 |
| 54 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19034222 |
| 55 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.18698100 |
| 56 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.15667811 |
| 57 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.15667811 |
| 58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15518732 |
| 59 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.14819092 |
| 60 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.11879340 |
| 61 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.11847267 |
| 62 | FUS_26573619_Chip-Seq_HEK293_Human | 1.11033168 |
| 63 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.09927593 |
| 64 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09739744 |
| 65 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.09349402 |
| 66 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.08393871 |
| 67 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.06593139 |
| 68 | GATA1_22025678_ChIP-Seq_K562_Human | 1.05895909 |
| 69 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.05082253 |
| 70 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.04025633 |
| 71 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.03466404 |
| 72 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.03271696 |
| 73 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.02327519 |
| 74 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01895872 |
| 75 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.01833425 |
| 76 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96784183 |
| 77 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.91844155 |
| 78 | KDM2B_26808549_Chip-Seq_REH_Human | 0.91740056 |
| 79 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.91527961 |
| 80 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91393184 |
| 81 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.90894998 |
| 82 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.90350899 |
| 83 | STAT3_23295773_ChIP-Seq_U87_Human | 0.89961990 |
| 84 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.88115450 |
| 85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.87834026 |
| 86 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.87403345 |
| 87 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.86967463 |
| 88 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.86145498 |
| 89 | CJUN_26792858_Chip-Seq_BT549_Human | 0.85180302 |
| 90 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.84644202 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83818379 |
| 92 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83818379 |
| 93 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.83530897 |
| 94 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.83154342 |
| 95 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.81585589 |
| 96 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.80887337 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.79910670 |
| 98 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.79877507 |
| 99 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.78680090 |
| 100 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.78603688 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000751_myopathy | 5.73675045 |
| 2 | MP0003646_muscle_fatigue | 5.16624129 |
| 3 | MP0005670_abnormal_white_adipose | 4.75322178 |
| 4 | MP0001661_extended_life_span | 3.90792165 |
| 5 | MP0000749_muscle_degeneration | 3.51738882 |
| 6 | MP0000750_abnormal_muscle_regeneration | 2.92786238 |
| 7 | MP0003705_abnormal_hypodermis_morpholog | 2.85823496 |
| 8 | MP0003183_abnormal_peptide_metabolism | 2.85756568 |
| 9 | MP0004145_abnormal_muscle_electrophysio | 2.67966790 |
| 10 | MP0004036_abnormal_muscle_relaxation | 2.47659207 |
| 11 | MP0000013_abnormal_adipose_tissue | 2.47124202 |
| 12 | MP0004084_abnormal_cardiac_muscle | 2.40841434 |
| 13 | MP0004130_abnormal_muscle_cell | 2.32540038 |
| 14 | MP0004233_abnormal_muscle_weight | 2.31294172 |
| 15 | MP0004510_myositis | 2.30008920 |
| 16 | MP0002269_muscular_atrophy | 2.26421342 |
| 17 | MP0002106_abnormal_muscle_physiology | 2.26012032 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 2.23936263 |
| 19 | MP0000747_muscle_weakness | 2.23074146 |
| 20 | MP0000372_irregular_coat_pigmentation | 2.19417067 |
| 21 | MP0002332_abnormal_exercise_endurance | 2.17089529 |
| 22 | MP0005360_urolithiasis | 2.12193800 |
| 23 | MP0005369_muscle_phenotype | 2.04820268 |
| 24 | MP0004215_abnormal_myocardial_fiber | 2.01344656 |
| 25 | MP0002108_abnormal_muscle_morphology | 1.92050202 |
| 26 | MP0004087_abnormal_muscle_fiber | 1.89290208 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.88010901 |
| 28 | MP0006138_congestive_heart_failure | 1.78522186 |
| 29 | MP0005275_abnormal_skin_tensile | 1.77056612 |
| 30 | MP0000759_abnormal_skeletal_muscle | 1.73895742 |
| 31 | MP0004484_altered_response_of | 1.72787643 |
| 32 | MP0002638_abnormal_pupillary_reflex | 1.72016456 |
| 33 | MP0005409_darkened_coat_color | 1.71275658 |
| 34 | MP0005620_abnormal_muscle_contractility | 1.63106637 |
| 35 | MP0005171_absent_coat_pigmentation | 1.61397161 |
| 36 | MP0004147_increased_porphyrin_level | 1.54054884 |
| 37 | MP0002127_abnormal_cardiovascular_syste | 1.51551408 |
| 38 | MP0005330_cardiomyopathy | 1.50444054 |
| 39 | MP0002972_abnormal_cardiac_muscle | 1.49349611 |
| 40 | MP0003137_abnormal_impulse_conducting | 1.44607903 |
| 41 | MP0008995_early_reproductive_senescence | 1.42228350 |
| 42 | MP0001986_abnormal_taste_sensitivity | 1.40508307 |
| 43 | MP0003136_yellow_coat_color | 1.37718205 |
| 44 | MP0001879_abnormal_lymphatic_vessel | 1.32607889 |
| 45 | MP0001544_abnormal_cardiovascular_syste | 1.30736552 |
| 46 | MP0005385_cardiovascular_system_phenoty | 1.30736552 |
| 47 | MP0008438_abnormal_cutaneous_collagen | 1.30661598 |
| 48 | MP0005503_abnormal_tendon_morphology | 1.25770468 |
| 49 | MP0002971_abnormal_brown_adipose | 1.25387994 |
| 50 | MP0003724_increased_susceptibility_to | 1.23641128 |
| 51 | MP0003045_fibrosis | 1.22657708 |
| 52 | MP0004185_abnormal_adipocyte_glucose | 1.13016209 |
| 53 | MP0006276_abnormal_autonomic_nervous | 1.11627328 |
| 54 | MP0000003_abnormal_adipose_tissue | 1.10371098 |
| 55 | MP0002938_white_spotting | 1.08801236 |
| 56 | MP0002163_abnormal_gland_morphology | 1.07193764 |
| 57 | MP0008775_abnormal_heart_ventricle | 1.03501149 |
| 58 | MP0010630_abnormal_cardiac_muscle | 1.00754588 |
| 59 | MP0004142_abnormal_muscle_tone | 0.97747900 |
| 60 | MP0004885_abnormal_endolymph | 0.93828128 |
| 61 | MP0000371_diluted_coat_color | 0.93821176 |
| 62 | MP0001486_abnormal_startle_reflex | 0.92853808 |
| 63 | MP0010368_abnormal_lymphatic_system | 0.90833926 |
| 64 | MP0005423_abnormal_somatic_nervous | 0.90787926 |
| 65 | MP0004085_abnormal_heartbeat | 0.87986510 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 0.87290834 |
| 67 | MP0000026_abnormal_inner_ear | 0.84400609 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.83987181 |
| 69 | MP0000733_abnormal_muscle_development | 0.80343021 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.75656353 |
| 71 | MP0004272_abnormal_basement_membrane | 0.75116103 |
| 72 | MP0001270_distended_abdomen | 0.73597196 |
| 73 | MP0005332_abnormal_amino_acid | 0.73026518 |
| 74 | MP0002095_abnormal_skin_pigmentation | 0.72402342 |
| 75 | MP0002132_abnormal_respiratory_system | 0.71731310 |
| 76 | MP0002736_abnormal_nociception_after | 0.69931981 |
| 77 | MP0001485_abnormal_pinna_reflex | 0.69164160 |
| 78 | MP0005266_abnormal_metabolism | 0.65148869 |
| 79 | MP0000467_abnormal_esophagus_morphology | 0.64188816 |
| 80 | MP0002138_abnormal_hepatobiliary_system | 0.64173887 |
| 81 | MP0005165_increased_susceptibility_to | 0.64089578 |
| 82 | MP0009115_abnormal_fat_cell | 0.62293916 |
| 83 | MP0000163_abnormal_cartilage_morphology | 0.60074408 |
| 84 | MP0003828_pulmonary_edema | 0.59501962 |
| 85 | MP0009697_abnormal_copulation | 0.58920655 |
| 86 | MP0001963_abnormal_hearing_physiology | 0.57796887 |
| 87 | MP0002075_abnormal_coat/hair_pigmentati | 0.56924343 |
| 88 | MP0002295_abnormal_pulmonary_circulatio | 0.56871166 |
| 89 | MP0009379_abnormal_foot_pigmentation | 0.55983481 |
| 90 | MP0004043_abnormal_pH_regulation | 0.55649532 |
| 91 | MP0002249_abnormal_larynx_morphology | 0.55619521 |
| 92 | MP0002735_abnormal_chemical_nociception | 0.55060126 |
| 93 | MP0009250_abnormal_appendicular_skeleto | 0.55018659 |
| 94 | MP0002089_abnormal_postnatal_growth/wei | 0.54223767 |
| 95 | MP0000534_abnormal_ureter_morphology | 0.54196948 |
| 96 | MP0008872_abnormal_physiological_respon | 0.53837815 |
| 97 | MP0002160_abnormal_reproductive_system | 0.53332285 |
| 98 | MP0005666_abnormal_adipose_tissue | 0.52744636 |
| 99 | MP0001968_abnormal_touch/_nociception | 0.52731102 |
| 100 | MP0005375_adipose_tissue_phenotype | 0.51598948 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 5.52668576 |
| 2 | Abnormality of alanine metabolism (HP:0010916) | 5.52668576 |
| 3 | Hyperalaninemia (HP:0003348) | 5.52668576 |
| 4 | Muscle fiber splitting (HP:0003555) | 5.32208590 |
| 5 | Tongue fasciculations (HP:0001308) | 5.18621660 |
| 6 | Muscle fibrillation (HP:0010546) | 4.77576236 |
| 7 | Calf muscle hypertrophy (HP:0008981) | 4.77482485 |
| 8 | Congenital sensorineural hearing impairment (HP:0008527) | 4.61907984 |
| 9 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.52661059 |
| 10 | Anomalous pulmonary venous return (HP:0010772) | 4.52407856 |
| 11 | Esophageal varix (HP:0002040) | 4.28148914 |
| 12 | Hyporeflexia of lower limbs (HP:0002600) | 4.05074853 |
| 13 | Difficulty running (HP:0009046) | 4.02866913 |
| 14 | Spontaneous hematomas (HP:0007420) | 3.91544959 |
| 15 | Abnormality of the pulmonary veins (HP:0011718) | 3.90035707 |
| 16 | Abnormality of the calf musculature (HP:0001430) | 3.81090626 |
| 17 | Muscle fiber inclusion bodies (HP:0100299) | 3.78356691 |
| 18 | Myopathic facies (HP:0002058) | 3.69378567 |
| 19 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.66393742 |
| 20 | Slow saccadic eye movements (HP:0000514) | 3.50262539 |
| 21 | Nemaline bodies (HP:0003798) | 3.40333990 |
| 22 | Pigmentary retinal degeneration (HP:0001146) | 3.34224581 |
| 23 | Bundle branch block (HP:0011710) | 3.33636349 |
| 24 | Diaphragmatic weakness (HP:0009113) | 3.24599399 |
| 25 | Ventricular tachycardia (HP:0004756) | 3.23789092 |
| 26 | Sudden death (HP:0001699) | 3.21607708 |
| 27 | Syncope (HP:0001279) | 3.19597881 |
| 28 | Increased connective tissue (HP:0009025) | 3.14538635 |
| 29 | EMG: myopathic abnormalities (HP:0003458) | 3.14509254 |
| 30 | Lipoatrophy (HP:0100578) | 3.01686357 |
| 31 | Maternal diabetes (HP:0009800) | 3.00648410 |
| 32 | Hyperkalemia (HP:0002153) | 2.99371061 |
| 33 | Exercise-induced myalgia (HP:0003738) | 2.97861574 |
| 34 | Constricted visual fields (HP:0001133) | 2.96488223 |
| 35 | Distal lower limb muscle weakness (HP:0009053) | 2.95989002 |
| 36 | Oral leukoplakia (HP:0002745) | 2.94936612 |
| 37 | Type 1 muscle fiber predominance (HP:0003803) | 2.86458943 |
| 38 | Rimmed vacuoles (HP:0003805) | 2.84683949 |
| 39 | Carpal bone hypoplasia (HP:0001498) | 2.79722428 |
| 40 | Atrial fibrillation (HP:0005110) | 2.74947067 |
| 41 | Hypoalphalipoproteinemia (HP:0003233) | 2.67654973 |
| 42 | Toxemia of pregnancy (HP:0100603) | 2.67503129 |
| 43 | White forelock (HP:0002211) | 2.52079679 |
| 44 | Myelomeningocele (HP:0002475) | 2.47759529 |
| 45 | Dilated cardiomyopathy (HP:0001644) | 2.47360867 |
| 46 | Absent phalangeal crease (HP:0006109) | 2.47311414 |
| 47 | Myoglobinuria (HP:0002913) | 2.44001897 |
| 48 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.37581659 |
| 49 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.37581659 |
| 50 | Single umbilical artery (HP:0001195) | 2.37581659 |
| 51 | Primary atrial arrhythmia (HP:0001692) | 2.34892696 |
| 52 | Long clavicles (HP:0000890) | 2.32395283 |
| 53 | Muscular dystrophy (HP:0003560) | 2.30796858 |
| 54 | Myocardial infarction (HP:0001658) | 2.29538327 |
| 55 | Oligomenorrhea (HP:0000876) | 2.26499619 |
| 56 | Areflexia of lower limbs (HP:0002522) | 2.25060180 |
| 57 | Abnormality of the odontoid process (HP:0003310) | 2.25048628 |
| 58 | Palpitations (HP:0001962) | 2.23379369 |
| 59 | Myotonia (HP:0002486) | 2.20842781 |
| 60 | Ventricular arrhythmia (HP:0004308) | 2.19667976 |
| 61 | Abnormal finger flexion creases (HP:0006143) | 2.18729626 |
| 62 | Supraventricular tachycardia (HP:0004755) | 2.17527275 |
| 63 | Short palpebral fissure (HP:0012745) | 2.16415483 |
| 64 | Abnormality of the renal collecting system (HP:0004742) | 2.15171826 |
| 65 | Right ventricular cardiomyopathy (HP:0011663) | 2.13435017 |
| 66 | Exercise-induced muscle cramps (HP:0003710) | 2.11483108 |
| 67 | Duplicated collecting system (HP:0000081) | 2.10424428 |
| 68 | Supraventricular arrhythmia (HP:0005115) | 2.09687221 |
| 69 | Patchy hypopigmentation of hair (HP:0011365) | 2.08439841 |
| 70 | Impaired smooth pursuit (HP:0007772) | 2.06288326 |
| 71 | Heart block (HP:0012722) | 2.05580125 |
| 72 | Atrioventricular block (HP:0001678) | 2.01848370 |
| 73 | Abnormality of the ischium (HP:0003174) | 2.01754145 |
| 74 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.97964088 |
| 75 | Subaortic stenosis (HP:0001682) | 1.97964088 |
| 76 | Ventricular fibrillation (HP:0001663) | 1.97712944 |
| 77 | Cavernous hemangioma (HP:0001048) | 1.97470629 |
| 78 | Chorioretinal atrophy (HP:0000533) | 1.97414496 |
| 79 | Paralysis (HP:0003470) | 1.95095596 |
| 80 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.92980343 |
| 81 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.92467151 |
| 82 | Short 1st metacarpal (HP:0010034) | 1.92467151 |
| 83 | Abnormality of homocysteine metabolism (HP:0010919) | 1.91558027 |
| 84 | Homocystinuria (HP:0002156) | 1.91558027 |
| 85 | Hypoplastic left heart (HP:0004383) | 1.88886491 |
| 86 | Increased variability in muscle fiber diameter (HP:0003557) | 1.85623457 |
| 87 | Abnormal atrioventricular conduction (HP:0005150) | 1.85332450 |
| 88 | Difficulty climbing stairs (HP:0003551) | 1.85106788 |
| 89 | Round ear (HP:0100830) | 1.82273703 |
| 90 | Lymphangioma (HP:0100764) | 1.80546797 |
| 91 | Fibular aplasia (HP:0002990) | 1.80371469 |
| 92 | Generalized aminoaciduria (HP:0002909) | 1.80270313 |
| 93 | EMG: neuropathic changes (HP:0003445) | 1.78929561 |
| 94 | Abnormality of serum amino acid levels (HP:0003112) | 1.78126477 |
| 95 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.77169811 |
| 96 | Conjugated hyperbilirubinemia (HP:0002908) | 1.75674132 |
| 97 | Action tremor (HP:0002345) | 1.72224355 |
| 98 | Decreased subcutaneous fat (HP:0001002) | 1.70881913 |
| 99 | Fatigue (HP:0012378) | 1.70787747 |
| 100 | J-shaped sella turcica (HP:0002680) | 1.70694297 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BLK | 8.16369540 |
| 2 | OBSCN | 4.81198222 |
| 3 | TTN | 3.82827230 |
| 4 | PHKG2 | 3.49429694 |
| 5 | PHKG1 | 3.49429694 |
| 6 | MAP2K3 | 3.39979161 |
| 7 | MAP3K3 | 2.86823202 |
| 8 | TIE1 | 1.94912438 |
| 9 | MUSK | 1.90111816 |
| 10 | SGK2 | 1.79792182 |
| 11 | MYLK | 1.71365318 |
| 12 | EPHB2 | 1.70820050 |
| 13 | SGK494 | 1.62001451 |
| 14 | SGK223 | 1.62001451 |
| 15 | MAP3K7 | 1.60162170 |
| 16 | CDK9 | 1.60124057 |
| 17 | MAPK12 | 1.34542029 |
| 18 | NEK1 | 1.33049308 |
| 19 | DYRK1B | 1.32920022 |
| 20 | SGK3 | 1.24602494 |
| 21 | LATS2 | 1.24292254 |
| 22 | NTRK2 | 1.23831107 |
| 23 | JAK3 | 1.23139821 |
| 24 | CAMK2D | 1.20134958 |
| 25 | CCNB1 | 1.17868176 |
| 26 | TRPM7 | 1.12641894 |
| 27 | PINK1 | 1.11592841 |
| 28 | CAMK4 | 1.09418591 |
| 29 | PRKAA2 | 1.09381624 |
| 30 | INSRR | 1.08315978 |
| 31 | LMTK2 | 1.02057963 |
| 32 | MAP2K1 | 0.98342138 |
| 33 | MAPK15 | 0.94972564 |
| 34 | RPS6KB2 | 0.93144848 |
| 35 | PDK2 | 0.87712371 |
| 36 | CAMK1 | 0.85957275 |
| 37 | MAPK7 | 0.85843074 |
| 38 | FGR | 0.85598486 |
| 39 | SYK | 0.84974181 |
| 40 | LATS1 | 0.84691054 |
| 41 | RPS6KA6 | 0.81967991 |
| 42 | STK4 | 0.81662831 |
| 43 | AKT2 | 0.80505049 |
| 44 | CAMK2B | 0.79163227 |
| 45 | PRPF4B | 0.78420407 |
| 46 | CAMK2G | 0.77738824 |
| 47 | MAPK4 | 0.77636047 |
| 48 | MARK1 | 0.75505385 |
| 49 | PRKD1 | 0.74701902 |
| 50 | WEE1 | 0.73021853 |
| 51 | PRKAA1 | 0.72351182 |
| 52 | PAK3 | 0.71673772 |
| 53 | ADRBK1 | 0.67548319 |
| 54 | PIK3CA | 0.63892902 |
| 55 | TGFBR2 | 0.63882143 |
| 56 | PTK6 | 0.62331309 |
| 57 | RPS6KC1 | 0.61462144 |
| 58 | RPS6KL1 | 0.61462144 |
| 59 | CAMK2A | 0.60525878 |
| 60 | GRK7 | 0.59201908 |
| 61 | PKN1 | 0.58049475 |
| 62 | NEK9 | 0.57850539 |
| 63 | TNIK | 0.56815326 |
| 64 | FRK | 0.54929461 |
| 65 | MAP2K4 | 0.54010682 |
| 66 | GRK1 | 0.51966581 |
| 67 | BCKDK | 0.50889325 |
| 68 | SGK1 | 0.49593455 |
| 69 | MAP3K6 | 0.49173834 |
| 70 | PRKACA | 0.47457819 |
| 71 | TAOK1 | 0.46876164 |
| 72 | PRKG1 | 0.46087253 |
| 73 | INSR | 0.45948993 |
| 74 | STK11 | 0.45789135 |
| 75 | WNK1 | 0.45133438 |
| 76 | MTOR | 0.44688754 |
| 77 | JAK2 | 0.41534693 |
| 78 | PDGFRB | 0.40830949 |
| 79 | RIPK1 | 0.38897921 |
| 80 | WNK4 | 0.38383142 |
| 81 | AKT1 | 0.37705303 |
| 82 | EPHA3 | 0.37096510 |
| 83 | RPS6KA1 | 0.35771352 |
| 84 | EGFR | 0.34797030 |
| 85 | NTRK3 | 0.32956419 |
| 86 | CSNK1A1 | 0.32761367 |
| 87 | MAP3K11 | 0.32614845 |
| 88 | ACVR1B | 0.32017181 |
| 89 | DAPK3 | 0.30429380 |
| 90 | MAP2K6 | 0.29769415 |
| 91 | RPS6KA3 | 0.29616318 |
| 92 | DAPK2 | 0.29447842 |
| 93 | PRKG2 | 0.29352348 |
| 94 | MATK | 0.29017022 |
| 95 | NTRK1 | 0.28417003 |
| 96 | ABL2 | 0.28295417 |
| 97 | PIK3CG | 0.26919803 |
| 98 | UHMK1 | 0.25772656 |
| 99 | RPS6KB1 | 0.24269262 |
| 100 | DMPK | 0.23744605 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 4.14931810 |
| 2 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.69400456 |
| 3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.48433698 |
| 4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.28096677 |
| 5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.58973215 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.45524805 |
| 7 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.42757599 |
| 8 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.39204571 |
| 9 | Sulfur relay system_Homo sapiens_hsa04122 | 2.12914826 |
| 10 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.03581953 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.93655426 |
| 12 | Morphine addiction_Homo sapiens_hsa05032 | 1.90523275 |
| 13 | GABAergic synapse_Homo sapiens_hsa04727 | 1.74764993 |
| 14 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.70264364 |
| 15 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.67265652 |
| 16 | Olfactory transduction_Homo sapiens_hsa04740 | 1.66275094 |
| 17 | Nicotine addiction_Homo sapiens_hsa05033 | 1.56535673 |
| 18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.49862526 |
| 19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.46774633 |
| 20 | Galactose metabolism_Homo sapiens_hsa00052 | 1.45160365 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.39986899 |
| 22 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.39384189 |
| 23 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.36262652 |
| 24 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.30804168 |
| 25 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.29675758 |
| 26 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.29003786 |
| 27 | ABC transporters_Homo sapiens_hsa02010 | 1.28266879 |
| 28 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.24690274 |
| 29 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.21755455 |
| 30 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.19433693 |
| 31 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.16027511 |
| 32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.14021346 |
| 33 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.12312072 |
| 34 | Renin secretion_Homo sapiens_hsa04924 | 1.08427033 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.08218566 |
| 36 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.06987494 |
| 37 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.06964933 |
| 38 | Taste transduction_Homo sapiens_hsa04742 | 1.06263304 |
| 39 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.02685778 |
| 40 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.02105132 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01982782 |
| 42 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.96285416 |
| 43 | Insulin secretion_Homo sapiens_hsa04911 | 0.95425081 |
| 44 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.95403104 |
| 45 | Bile secretion_Homo sapiens_hsa04976 | 0.95023499 |
| 46 | Circadian rhythm_Homo sapiens_hsa04710 | 0.92939876 |
| 47 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.90941017 |
| 48 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.90585747 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90416479 |
| 50 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.84330789 |
| 51 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.84036891 |
| 52 | Alcoholism_Homo sapiens_hsa05034 | 0.82753310 |
| 53 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.81124902 |
| 54 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.80711438 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80362173 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.79695523 |
| 57 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.79210347 |
| 58 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.77177040 |
| 59 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.77129014 |
| 60 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.75819222 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72876539 |
| 62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72851650 |
| 63 | Parkinsons disease_Homo sapiens_hsa05012 | 0.72074540 |
| 64 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.71961143 |
| 65 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70879498 |
| 66 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.68762957 |
| 67 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.67731496 |
| 68 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.66857016 |
| 69 | Alzheimers disease_Homo sapiens_hsa05010 | 0.65951016 |
| 70 | Peroxisome_Homo sapiens_hsa04146 | 0.65008470 |
| 71 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63507327 |
| 72 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.62907556 |
| 73 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.62907493 |
| 74 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.62711145 |
| 75 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.62056558 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60738747 |
| 77 | Cocaine addiction_Homo sapiens_hsa05030 | 0.58025832 |
| 78 | Salivary secretion_Homo sapiens_hsa04970 | 0.57834127 |
| 79 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.55508800 |
| 80 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.55124973 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.54248770 |
| 82 | Carbon metabolism_Homo sapiens_hsa01200 | 0.52909492 |
| 83 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.52754217 |
| 84 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.51571962 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51357524 |
| 86 | Huntingtons disease_Homo sapiens_hsa05016 | 0.51166854 |
| 87 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.49713960 |
| 88 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.49174789 |
| 89 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.48764823 |
| 90 | Insulin resistance_Homo sapiens_hsa04931 | 0.47942771 |
| 91 | Ribosome_Homo sapiens_hsa03010 | 0.45727116 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45725349 |
| 93 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45372448 |
| 94 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.44663987 |
| 95 | Histidine metabolism_Homo sapiens_hsa00340 | 0.42469190 |
| 96 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.42399793 |
| 97 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40438936 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39235276 |
| 99 | Platelet activation_Homo sapiens_hsa04611 | 0.38698005 |
| 100 | Viral myocarditis_Homo sapiens_hsa05416 | 0.36658473 |

