Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 5.35180754 |
2 | mitotic sister chromatid cohesion (GO:0007064) | 5.28201865 |
3 | nuclear pore organization (GO:0006999) | 5.07281551 |
4 | central nervous system myelination (GO:0022010) | 4.96178960 |
5 | axon ensheathment in central nervous system (GO:0032291) | 4.96178960 |
6 | protein localization to kinetochore (GO:0034501) | 4.70098070 |
7 | mitotic chromosome condensation (GO:0007076) | 4.69358692 |
8 | protein localization to chromosome, centromeric region (GO:0071459) | 4.53909619 |
9 | mitotic sister chromatid segregation (GO:0000070) | 3.88679396 |
10 | sister chromatid segregation (GO:0000819) | 3.83984653 |
11 | DNA replication checkpoint (GO:0000076) | 3.81905608 |
12 | IMP biosynthetic process (GO:0006188) | 3.81108278 |
13 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.79219086 |
14 | pore complex assembly (GO:0046931) | 3.76189592 |
15 | heterochromatin organization (GO:0070828) | 3.63517606 |
16 | IMP metabolic process (GO:0046040) | 3.59331900 |
17 | myelination (GO:0042552) | 3.50292270 |
18 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.49297811 |
19 | axon ensheathment (GO:0008366) | 3.48995705 |
20 | ensheathment of neurons (GO:0007272) | 3.48995705 |
21 | regulation of helicase activity (GO:0051095) | 3.48033110 |
22 | formation of translation preinitiation complex (GO:0001731) | 3.46325899 |
23 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.36152657 |
24 | rRNA transcription (GO:0009303) | 3.35609895 |
25 | pre-miRNA processing (GO:0031054) | 3.34081138 |
26 | negative regulation of neurotransmitter secretion (GO:0046929) | 3.20907473 |
27 | regulation of DNA endoreduplication (GO:0032875) | 3.19966930 |
28 | maturation of SSU-rRNA (GO:0030490) | 3.14943878 |
29 | regulation of centriole replication (GO:0046599) | 3.13344342 |
30 | histone exchange (GO:0043486) | 3.13074163 |
31 | mitotic nuclear envelope disassembly (GO:0007077) | 3.12012805 |
32 | purine nucleobase biosynthetic process (GO:0009113) | 3.11808812 |
33 | ribosomal large subunit biogenesis (GO:0042273) | 3.11506447 |
34 | transcription from mitochondrial promoter (GO:0006390) | 3.10985634 |
35 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.10365630 |
36 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.10365630 |
37 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.10365630 |
38 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.08981455 |
39 | ribosomal small subunit biogenesis (GO:0042274) | 3.06589054 |
40 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.05938159 |
41 | DNA replication-independent nucleosome organization (GO:0034724) | 3.05938159 |
42 | membrane disassembly (GO:0030397) | 3.01970163 |
43 | nuclear envelope disassembly (GO:0051081) | 3.01970163 |
44 | negative regulation of neurotransmitter transport (GO:0051589) | 3.00962902 |
45 | regulation of chromosome segregation (GO:0051983) | 3.00343573 |
46 | negative regulation of DNA repair (GO:0045738) | 2.96809127 |
47 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.95029388 |
48 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.95029388 |
49 | negative regulation of chromosome segregation (GO:0051985) | 2.91659050 |
50 | sister chromatid cohesion (GO:0007062) | 2.90937503 |
51 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.89893202 |
52 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.89893202 |
53 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.89893202 |
54 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.89893202 |
55 | negative regulation of sister chromatid segregation (GO:0033046) | 2.89893202 |
56 | regulation of centrosome cycle (GO:0046605) | 2.86460833 |
57 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.86361989 |
58 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.86361989 |
59 | regulation of sister chromatid segregation (GO:0033045) | 2.86361989 |
60 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.83531634 |
61 | regulation of DNA methylation (GO:0044030) | 2.82723042 |
62 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 2.81968418 |
63 | protein localization to chromosome (GO:0034502) | 2.81784629 |
64 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.79732027 |
65 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.79441603 |
66 | presynaptic membrane assembly (GO:0097105) | 2.78266355 |
67 | regulation of translational fidelity (GO:0006450) | 2.78264858 |
68 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.77949122 |
69 | DNA strand elongation (GO:0022616) | 2.76108172 |
70 | nucleobase biosynthetic process (GO:0046112) | 2.71174066 |
71 | negative regulation of mRNA metabolic process (GO:1903312) | 2.70200770 |
72 | negative regulation of mRNA processing (GO:0050686) | 2.70067082 |
73 | lateral sprouting from an epithelium (GO:0060601) | 2.69841302 |
74 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.69630788 |
75 | non-recombinational repair (GO:0000726) | 2.69630788 |
76 | chromosome segregation (GO:0007059) | 2.69303505 |
77 | negative regulation of RNA splicing (GO:0033119) | 2.67940107 |
78 | spindle assembly checkpoint (GO:0071173) | 2.67721350 |
79 | mitotic spindle assembly checkpoint (GO:0007094) | 2.67081869 |
80 | chromosome condensation (GO:0030261) | 2.67013652 |
81 | ribosome biogenesis (GO:0042254) | 2.66625302 |
82 | NLS-bearing protein import into nucleus (GO:0006607) | 2.66047506 |
83 | translational initiation (GO:0006413) | 2.65407928 |
84 | ER overload response (GO:0006983) | 2.65342535 |
85 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.64897201 |
86 | neuron cell-cell adhesion (GO:0007158) | 2.62914151 |
87 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.62568346 |
88 | kinetochore assembly (GO:0051382) | 2.60346531 |
89 | response to X-ray (GO:0010165) | 2.59971604 |
90 | fatty acid elongation (GO:0030497) | 2.59344527 |
91 | translational termination (GO:0006415) | 2.57396504 |
92 | presynaptic membrane organization (GO:0097090) | 2.54773620 |
93 | negative regulation of myoblast differentiation (GO:0045662) | 2.52818472 |
94 | establishment of mitochondrion localization (GO:0051654) | 2.49463190 |
95 | * nuclear envelope reassembly (GO:0031468) | 2.48919213 |
96 | * mitotic nuclear envelope reassembly (GO:0007084) | 2.48919213 |
97 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.43266709 |
98 | cellular protein complex localization (GO:0034629) | 2.42302170 |
99 | DNA unwinding involved in DNA replication (GO:0006268) | 2.42118252 |
100 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.39294852 |
101 | regulation of collateral sprouting (GO:0048670) | 2.34990483 |
102 | regulation of exit from mitosis (GO:0007096) | 2.34742746 |
103 | histone H2B ubiquitination (GO:0033523) | 2.31964395 |
104 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.31068180 |
105 | establishment of integrated proviral latency (GO:0075713) | 2.26170832 |
106 | Rap protein signal transduction (GO:0032486) | 2.25557301 |
107 | termination of RNA polymerase III transcription (GO:0006386) | 2.23122666 |
108 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.23122666 |
109 | positive regulation of actin filament depolymerization (GO:0030836) | 2.22581149 |
110 | mitotic metaphase plate congression (GO:0007080) | 2.21010780 |
111 | protein neddylation (GO:0045116) | 2.19878302 |
112 | DNA replication initiation (GO:0006270) | 2.19084136 |
113 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.14650724 |
114 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.14511293 |
115 | cullin deneddylation (GO:0010388) | 2.13545074 |
116 | positive regulation of chromosome segregation (GO:0051984) | 2.13368493 |
117 | substantia nigra development (GO:0021762) | 2.12218425 |
118 | astrocyte development (GO:0014002) | 2.10316346 |
119 | DNA ligation (GO:0006266) | 2.09983378 |
120 | myelination in peripheral nervous system (GO:0022011) | 2.08009242 |
121 | peripheral nervous system axon ensheathment (GO:0032292) | 2.08009242 |
122 | regulation of spindle organization (GO:0090224) | 2.06877765 |
123 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 2.06467581 |
124 | RNA capping (GO:0036260) | 2.06297042 |
125 | 7-methylguanosine RNA capping (GO:0009452) | 2.06297042 |
126 | myelin maintenance (GO:0043217) | 2.06047654 |
127 | establishment of viral latency (GO:0019043) | 2.05685786 |
128 | metaphase plate congression (GO:0051310) | 2.04351775 |
129 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.02434899 |
130 | viral mRNA export from host cell nucleus (GO:0046784) | 2.02167105 |
131 | 7-methylguanosine mRNA capping (GO:0006370) | 2.00336453 |
132 | asymmetric protein localization (GO:0008105) | 2.00164579 |
133 | protein complex localization (GO:0031503) | 1.96556273 |
134 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 1.96336379 |
135 | CENP-A containing nucleosome assembly (GO:0034080) | 1.96070154 |
136 | microtubule polymerization or depolymerization (GO:0031109) | 1.95574885 |
137 | negative regulation of protein localization to cell surface (GO:2000009) | 1.94124628 |
138 | regulation of mitotic spindle organization (GO:0060236) | 1.92993320 |
139 | kinetochore organization (GO:0051383) | 1.91226331 |
140 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 1.91078357 |
141 | proteasome assembly (GO:0043248) | 1.90946639 |
142 | regulation of RNA export from nucleus (GO:0046831) | 1.90906922 |
143 | oligodendrocyte differentiation (GO:0048709) | 1.89885160 |
144 | negative regulation by host of viral transcription (GO:0043922) | 1.88446255 |
145 | dermatan sulfate metabolic process (GO:0030205) | 1.87771641 |
146 | establishment of chromosome localization (GO:0051303) | 1.87263700 |
147 | chromatin remodeling at centromere (GO:0031055) | 1.86983541 |
148 | regulation of neuron projection regeneration (GO:0070570) | 1.85816474 |
149 | regulation of axon regeneration (GO:0048679) | 1.85816474 |
150 | negative regulation of JAK-STAT cascade (GO:0046426) | 1.82914002 |
151 | dermatan sulfate biosynthetic process (GO:0030208) | 1.81968948 |
152 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 1.81870011 |
153 | postsynaptic membrane organization (GO:0001941) | 1.80536897 |
154 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 1.79975409 |
155 | regulation of mitotic spindle checkpoint (GO:1903504) | 1.79975409 |
156 | regulation of myelination (GO:0031641) | 1.79963788 |
157 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 1.79896703 |
158 | RNA splicing, via transesterification reactions (GO:0000375) | 1.79525438 |
159 | apical protein localization (GO:0045176) | 1.79518884 |
160 | termination of RNA polymerase I transcription (GO:0006363) | 1.79363217 |
161 | ribosome assembly (GO:0042255) | 1.79272375 |
162 | mitotic cytokinesis (GO:0000281) | 1.78716474 |
163 | spliceosomal snRNP assembly (GO:0000387) | 1.78652516 |
164 | spindle checkpoint (GO:0031577) | 1.77951674 |
165 | negative regulation of axonogenesis (GO:0050771) | 1.77391928 |
166 | preassembly of GPI anchor in ER membrane (GO:0016254) | 1.77350955 |
167 | mRNA polyadenylation (GO:0006378) | 1.77304191 |
168 | DNA strand elongation involved in DNA replication (GO:0006271) | 1.76757285 |
169 | transmission of nerve impulse (GO:0019226) | 1.76670226 |
170 | mRNA splicing, via spliceosome (GO:0000398) | 1.76362632 |
171 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 1.76362632 |
172 | transcription-coupled nucleotide-excision repair (GO:0006283) | 1.76293852 |
173 | pseudouridine synthesis (GO:0001522) | 1.75636455 |
174 | mitotic spindle checkpoint (GO:0071174) | 1.75611591 |
175 | dendritic spine morphogenesis (GO:0060997) | 1.74764007 |
176 | RNA polyadenylation (GO:0043631) | 1.74430332 |
177 | protein deneddylation (GO:0000338) | 1.74130883 |
178 | DNA topological change (GO:0006265) | 1.73767104 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.88165575 |
2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.63497173 |
3 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.66315196 |
4 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.31576277 |
5 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.28399257 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.26551062 |
7 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.19776061 |
8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.06794228 |
9 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.01161280 |
10 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.00569916 |
11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.97529902 |
12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.96347926 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.92680174 |
14 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.89672721 |
15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.83983095 |
16 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.82981405 |
17 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.82339212 |
18 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.80378260 |
19 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.80378260 |
20 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.80378260 |
21 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.80327210 |
22 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.78482477 |
23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.74642430 |
24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.73535908 |
25 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.69817225 |
26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.69551149 |
27 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69397370 |
28 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.68553934 |
29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.67676162 |
30 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.66210346 |
31 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.63645415 |
32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62664284 |
33 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.61952894 |
34 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.59394155 |
35 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.58984396 |
36 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.55446764 |
37 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.54169968 |
38 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.52508701 |
39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.52250234 |
40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.50327743 |
41 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.49750042 |
42 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.48519917 |
43 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.45068473 |
44 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.40539018 |
45 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.39334527 |
46 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.37103091 |
47 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.36554929 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.35436852 |
49 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.35106941 |
50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.34504180 |
51 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.34481878 |
52 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.34200053 |
53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.33464458 |
54 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.33240918 |
55 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.30782750 |
56 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.30317472 |
57 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.29578111 |
58 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28664515 |
59 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.26655622 |
60 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.25978888 |
61 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.25726950 |
62 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.25448195 |
63 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.24422970 |
64 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.22578469 |
65 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.21953866 |
66 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.21729834 |
67 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.21657467 |
68 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.20567491 |
69 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.17906337 |
70 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.17292843 |
71 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16911971 |
72 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16229324 |
73 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.14485220 |
74 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.12852938 |
75 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.11916750 |
76 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.11622171 |
77 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.10545953 |
78 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08901384 |
79 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.08863914 |
80 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.08849706 |
81 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.06925052 |
82 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.05064623 |
83 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.01259626 |
84 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.00618000 |
85 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.00471014 |
86 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.99670344 |
87 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98739438 |
88 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98726439 |
89 | VDR_22108803_ChIP-Seq_LS180_Human | 0.98161751 |
90 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.98069031 |
91 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.97386557 |
92 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.96575484 |
93 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.96246975 |
94 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.95916265 |
95 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.95242995 |
96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.94907072 |
97 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92588649 |
98 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.92071727 |
99 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91520567 |
100 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.91473351 |
101 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.91124993 |
102 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.90211968 |
103 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.90009495 |
104 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.89464184 |
105 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.88367502 |
106 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.87720090 |
107 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.87690856 |
108 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.87684230 |
109 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.87523901 |
110 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 0.87497931 |
111 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.86843795 |
112 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.86358408 |
113 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.85713226 |
114 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.85546378 |
115 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.85335027 |
116 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.84890994 |
117 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.84532029 |
118 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84350124 |
119 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.84071581 |
120 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.83966276 |
121 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.83653755 |
122 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.82543901 |
123 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.82349759 |
124 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.81826213 |
125 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.81576553 |
126 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.80772510 |
127 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.80424763 |
128 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.80223316 |
129 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.79373282 |
130 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.79373282 |
131 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.79015374 |
132 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.79009569 |
133 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.78725884 |
134 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.77572799 |
135 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77153791 |
136 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.76407188 |
137 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 0.75704633 |
138 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.75451141 |
139 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.74953295 |
140 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.74805384 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010352_gastrointestinal_tract_polyps | 3.27453747 |
2 | MP0003880_abnormal_central_pattern | 3.15323888 |
3 | MP0003890_abnormal_embryonic-extraembry | 3.14296239 |
4 | MP0008057_abnormal_DNA_replication | 3.02295650 |
5 | MP0010234_abnormal_vibrissa_follicle | 2.72647957 |
6 | MP0000920_abnormal_myelination | 2.54397639 |
7 | MP0002796_impaired_skin_barrier | 2.24725235 |
8 | MP0009697_abnormal_copulation | 2.17366454 |
9 | MP0001529_abnormal_vocalization | 2.13801843 |
10 | MP0005409_darkened_coat_color | 1.98712488 |
11 | MP0008932_abnormal_embryonic_tissue | 1.92042298 |
12 | MP0005171_absent_coat_pigmentation | 1.87998026 |
13 | MP0004185_abnormal_adipocyte_glucose | 1.81598907 |
14 | MP0010307_abnormal_tumor_latency | 1.75112160 |
15 | MP0003221_abnormal_cardiomyocyte_apopto | 1.73205202 |
16 | MP0004957_abnormal_blastocyst_morpholog | 1.71054320 |
17 | MP0010094_abnormal_chromosome_stability | 1.70824953 |
18 | MP0003718_maternal_effect | 1.69813158 |
19 | MP0002009_preneoplasia | 1.67241599 |
20 | MP0004270_analgesia | 1.67010874 |
21 | MP0008877_abnormal_DNA_methylation | 1.65537080 |
22 | MP0003941_abnormal_skin_development | 1.63578035 |
23 | MP0004742_abnormal_vestibular_system | 1.63555550 |
24 | MP0000579_abnormal_nail_morphology | 1.62893131 |
25 | MP0005501_abnormal_skin_physiology | 1.60171780 |
26 | MP0008007_abnormal_cellular_replicative | 1.58613364 |
27 | MP0003136_yellow_coat_color | 1.57119133 |
28 | MP0009672_abnormal_birth_weight | 1.56869410 |
29 | MP0000537_abnormal_urethra_morphology | 1.53531847 |
30 | MP0003077_abnormal_cell_cycle | 1.49010611 |
31 | MP0000778_abnormal_nervous_system | 1.46068259 |
32 | MP0010030_abnormal_orbit_morphology | 1.40557208 |
33 | MP0003937_abnormal_limbs/digits/tail_de | 1.39189898 |
34 | MP0001188_hyperpigmentation | 1.38635176 |
35 | MP0003123_paternal_imprinting | 1.37058875 |
36 | MP0004859_abnormal_synaptic_plasticity | 1.34755398 |
37 | MP0005503_abnormal_tendon_morphology | 1.34526625 |
38 | MP0005666_abnormal_adipose_tissue | 1.34332833 |
39 | MP0001905_abnormal_dopamine_level | 1.34104294 |
40 | MP0002080_prenatal_lethality | 1.33159628 |
41 | MP0003950_abnormal_plasma_membrane | 1.32883537 |
42 | MP0005623_abnormal_meninges_morphology | 1.31218077 |
43 | MP0009250_abnormal_appendicular_skeleto | 1.30863470 |
44 | MP0003111_abnormal_nucleus_morphology | 1.30574668 |
45 | MP0001485_abnormal_pinna_reflex | 1.29634549 |
46 | MP0005423_abnormal_somatic_nervous | 1.26274087 |
47 | MP0002086_abnormal_extraembryonic_tissu | 1.25962860 |
48 | MP0001486_abnormal_startle_reflex | 1.23242906 |
49 | MP0009379_abnormal_foot_pigmentation | 1.23166642 |
50 | MP0003938_abnormal_ear_development | 1.22740040 |
51 | MP0006292_abnormal_olfactory_placode | 1.20481269 |
52 | MP0004233_abnormal_muscle_weight | 1.18630067 |
53 | MP0001730_embryonic_growth_arrest | 1.18078959 |
54 | MP0000313_abnormal_cell_death | 1.17954121 |
55 | MP0008058_abnormal_DNA_repair | 1.16956639 |
56 | MP0003121_genomic_imprinting | 1.12678585 |
57 | MP0001299_abnormal_eye_distance/ | 1.12329947 |
58 | MP0003693_abnormal_embryo_hatching | 1.10109255 |
59 | MP0000350_abnormal_cell_proliferation | 1.09902081 |
60 | MP0001216_abnormal_epidermal_layer | 1.06388000 |
61 | MP0004264_abnormal_extraembryonic_tissu | 1.05737550 |
62 | MP0005670_abnormal_white_adipose | 1.05348092 |
63 | MP0003315_abnormal_perineum_morphology | 1.04355506 |
64 | MP0009703_decreased_birth_body | 1.03757951 |
65 | MP0010678_abnormal_skin_adnexa | 1.03651299 |
66 | MP0003635_abnormal_synaptic_transmissio | 1.02560822 |
67 | MP0002272_abnormal_nervous_system | 1.02173354 |
68 | MP0002697_abnormal_eye_size | 1.01287501 |
69 | MP0001293_anophthalmia | 0.99781643 |
70 | MP0004142_abnormal_muscle_tone | 0.99661573 |
71 | MP0003453_abnormal_keratinocyte_physiol | 0.99622677 |
72 | MP0003861_abnormal_nervous_system | 0.99569611 |
73 | MP0002084_abnormal_developmental_patter | 0.98987801 |
74 | MP0002064_seizures | 0.97654472 |
75 | MP0002085_abnormal_embryonic_tissue | 0.96974963 |
76 | MP0001348_abnormal_lacrimal_gland | 0.95102464 |
77 | MP0009745_abnormal_behavioral_response | 0.93886649 |
78 | MP0000383_abnormal_hair_follicle | 0.93714197 |
79 | MP0001697_abnormal_embryo_size | 0.93513714 |
80 | MP0000377_abnormal_hair_follicle | 0.92908884 |
81 | MP0003755_abnormal_palate_morphology | 0.90982262 |
82 | MP0000733_abnormal_muscle_development | 0.90385536 |
83 | MP0002938_white_spotting | 0.89889348 |
84 | MP0005375_adipose_tissue_phenotype | 0.89488623 |
85 | MP0003385_abnormal_body_wall | 0.88750327 |
86 | MP0002282_abnormal_trachea_morphology | 0.88361819 |
87 | MP0002822_catalepsy | 0.87035558 |
88 | MP0000566_synostosis | 0.86825198 |
89 | MP0000955_abnormal_spinal_cord | 0.86822984 |
90 | MP0002653_abnormal_ependyma_morphology | 0.85533933 |
91 | MP0000627_abnormal_mammary_gland | 0.83514759 |
92 | MP0002932_abnormal_joint_morphology | 0.83441526 |
93 | MP0000647_abnormal_sebaceous_gland | 0.83375754 |
94 | MP0004215_abnormal_myocardial_fiber | 0.83074501 |
95 | MP0000516_abnormal_urinary_system | 0.83059950 |
96 | MP0005367_renal/urinary_system_phenotyp | 0.83059950 |
97 | MP0003634_abnormal_glial_cell | 0.82667226 |
98 | MP0004197_abnormal_fetal_growth/weight/ | 0.82374428 |
99 | MP0000428_abnormal_craniofacial_morphol | 0.82312725 |
100 | MP0002063_abnormal_learning/memory/cond | 0.82259474 |
101 | MP0003122_maternal_imprinting | 0.82060848 |
102 | MP0002734_abnormal_mechanical_nocicepti | 0.81777174 |
103 | MP0000049_abnormal_middle_ear | 0.80830408 |
104 | MP0003632_abnormal_nervous_system | 0.80800473 |
105 | MP0002114_abnormal_axial_skeleton | 0.80484334 |
106 | MP0003567_abnormal_fetal_cardiomyocyte | 0.79874683 |
107 | MP0002882_abnormal_neuron_morphology | 0.79811837 |
108 | MP0002163_abnormal_gland_morphology | 0.78667143 |
109 | MP0001672_abnormal_embryogenesis/_devel | 0.77745067 |
110 | MP0005380_embryogenesis_phenotype | 0.77745067 |
111 | MP0006035_abnormal_mitochondrial_morpho | 0.77187053 |
112 | MP0002210_abnormal_sex_determination | 0.77031589 |
113 | MP0000432_abnormal_head_morphology | 0.77022855 |
114 | MP0003119_abnormal_digestive_system | 0.76777350 |
115 | MP0004134_abnormal_chest_morphology | 0.76766601 |
116 | MP0000358_abnormal_cell_content/ | 0.76736288 |
117 | MP0005384_cellular_phenotype | 0.76727756 |
118 | MP0004885_abnormal_endolymph | 0.76647141 |
119 | MP0002160_abnormal_reproductive_system | 0.76577740 |
120 | MP0001145_abnormal_male_reproductive | 0.75337856 |
121 | MP0003705_abnormal_hypodermis_morpholog | 0.75286800 |
122 | MP0003935_abnormal_craniofacial_develop | 0.75227055 |
123 | MP0002572_abnormal_emotion/affect_behav | 0.75216051 |
124 | MP0002152_abnormal_brain_morphology | 0.74884775 |
125 | MP0001881_abnormal_mammary_gland | 0.74344692 |
126 | MP0001879_abnormal_lymphatic_vessel | 0.73897005 |
127 | MP0003786_premature_aging | 0.73840695 |
128 | MP0005508_abnormal_skeleton_morphology | 0.73406796 |
129 | MP0003984_embryonic_growth_retardation | 0.73307832 |
130 | MP0004133_heterotaxia | 0.72493607 |
131 | MP0005621_abnormal_cell_physiology | 0.72387785 |
132 | MP0010630_abnormal_cardiac_muscle | 0.72368527 |
133 | MP0001968_abnormal_touch/_nociception | 0.72277974 |
134 | MP0000613_abnormal_salivary_gland | 0.72213941 |
135 | MP0002751_abnormal_autonomic_nervous | 0.71636579 |
136 | MP0004782_abnormal_surfactant_physiolog | 0.71338247 |
137 | MP0005187_abnormal_penis_morphology | 0.71323206 |
138 | MP0002006_tumorigenesis | 0.71259442 |
139 | MP0003943_abnormal_hepatobiliary_system | 0.71167613 |
140 | MP0002396_abnormal_hematopoietic_system | 0.70928283 |
141 | MP0001919_abnormal_reproductive_system | 0.70694017 |
142 | MP0005076_abnormal_cell_differentiation | 0.70620078 |
143 | MP0002269_muscular_atrophy | 0.70405683 |
144 | MP0002060_abnormal_skin_morphology | 0.69646048 |
145 | MP0001929_abnormal_gametogenesis | 0.69632319 |
146 | MP0000762_abnormal_tongue_morphology | 0.69448212 |
147 | MP0002177_abnormal_outer_ear | 0.69203465 |
148 | MP0002752_abnormal_somatic_nervous | 0.68689398 |
149 | MP0003936_abnormal_reproductive_system | 0.68189256 |
150 | MP0002088_abnormal_embryonic_growth/wei | 0.67724713 |
151 | MP0001191_abnormal_skin_condition | 0.67411558 |
152 | MP0001177_atelectasis | 0.67226095 |
153 | MP0002111_abnormal_tail_morphology | 0.66828348 |
154 | MP0003690_abnormal_glial_cell | 0.66756927 |
155 | MP0001727_abnormal_embryo_implantation | 0.66598219 |
156 | MP0001286_abnormal_eye_development | 0.66538754 |
157 | MP0009046_muscle_twitch | 0.66453134 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.67618648 |
2 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.67618648 |
3 | Cerebral hypomyelination (HP:0006808) | 3.41102365 |
4 | Volvulus (HP:0002580) | 3.26604009 |
5 | Hypoplasia of the pons (HP:0012110) | 3.23644770 |
6 | Abnormality of the pons (HP:0007361) | 3.14032326 |
7 | Papillary thyroid carcinoma (HP:0002895) | 2.88941644 |
8 | Peripheral hypomyelination (HP:0007182) | 2.77786990 |
9 | Abnormality of the corticospinal tract (HP:0002492) | 2.71942051 |
10 | Septate vagina (HP:0001153) | 2.69808405 |
11 | Rhabdomyosarcoma (HP:0002859) | 2.66303520 |
12 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.63492161 |
13 | Multiple enchondromatosis (HP:0005701) | 2.63290293 |
14 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.60743900 |
15 | Adrenal hypoplasia (HP:0000835) | 2.59765093 |
16 | Cerebellar dysplasia (HP:0007033) | 2.59344343 |
17 | Parakeratosis (HP:0001036) | 2.53731471 |
18 | Stenosis of the external auditory canal (HP:0000402) | 2.50743022 |
19 | Fragile nails (HP:0001808) | 2.49704106 |
20 | Abnormality of chromosome stability (HP:0003220) | 2.48275982 |
21 | Embryonal renal neoplasm (HP:0011794) | 2.46556739 |
22 | Lip pit (HP:0100267) | 2.45780210 |
23 | Ankyloglossia (HP:0010296) | 2.44990416 |
24 | Hypoplastic pelvis (HP:0008839) | 2.44845359 |
25 | Reticulocytopenia (HP:0001896) | 2.43305481 |
26 | Abnormality of the labia minora (HP:0012880) | 2.37076916 |
27 | Aplasia involving forearm bones (HP:0009822) | 2.37053997 |
28 | Absent forearm bone (HP:0003953) | 2.37053997 |
29 | Esophageal atresia (HP:0002032) | 2.34843991 |
30 | Absent radius (HP:0003974) | 2.34537940 |
31 | Cortical dysplasia (HP:0002539) | 2.29827296 |
32 | Abnormality of the salivary glands (HP:0010286) | 2.29303252 |
33 | Colon cancer (HP:0003003) | 2.27879895 |
34 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.27340432 |
35 | Increased nuchal translucency (HP:0010880) | 2.24612616 |
36 | Macrocytic anemia (HP:0001972) | 2.24563529 |
37 | Aqueductal stenosis (HP:0002410) | 2.18226854 |
38 | Birth length less than 3rd percentile (HP:0003561) | 2.16574641 |
39 | Fused cervical vertebrae (HP:0002949) | 2.15434006 |
40 | Deep philtrum (HP:0002002) | 2.15053838 |
41 | Selective tooth agenesis (HP:0001592) | 2.11579188 |
42 | Abnormality of the preputium (HP:0100587) | 2.10987538 |
43 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.10082251 |
44 | Abnormality of the nasal septum (HP:0000419) | 2.10063991 |
45 | Acute myeloid leukemia (HP:0004808) | 2.09297388 |
46 | Chin dimple (HP:0010751) | 2.08211991 |
47 | Breast hypoplasia (HP:0003187) | 2.07999110 |
48 | Meckel diverticulum (HP:0002245) | 2.06319742 |
49 | Progressive external ophthalmoplegia (HP:0000590) | 2.05088603 |
50 | Medulloblastoma (HP:0002885) | 2.04667903 |
51 | Non-midline cleft lip (HP:0100335) | 2.03514913 |
52 | Facial cleft (HP:0002006) | 2.03432362 |
53 | Abnormality of the ileum (HP:0001549) | 2.02269698 |
54 | Termporal pattern (HP:0011008) | 2.02163522 |
55 | Insidious onset (HP:0003587) | 2.02163522 |
56 | Neoplasm of striated muscle (HP:0009728) | 2.01629834 |
57 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.01189270 |
58 | Type II lissencephaly (HP:0007260) | 1.99263631 |
59 | Poikiloderma (HP:0001029) | 1.98331566 |
60 | Duplicated collecting system (HP:0000081) | 1.96829137 |
61 | Sensory axonal neuropathy (HP:0003390) | 1.95798107 |
62 | High anterior hairline (HP:0009890) | 1.95279167 |
63 | Asplenia (HP:0001746) | 1.93257648 |
64 | Irregular epiphyses (HP:0010582) | 1.92603110 |
65 | Abnormal hair whorl (HP:0010721) | 1.92197103 |
66 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.91908080 |
67 | Increased serum pyruvate (HP:0003542) | 1.91817325 |
68 | Abnormality of glycolysis (HP:0004366) | 1.91817325 |
69 | Alacrima (HP:0000522) | 1.90684361 |
70 | Right ventricular cardiomyopathy (HP:0011663) | 1.90019117 |
71 | Hypoplastic labia majora (HP:0000059) | 1.89219026 |
72 | Postnatal microcephaly (HP:0005484) | 1.84473583 |
73 | Pallor (HP:0000980) | 1.83964837 |
74 | Overlapping toe (HP:0001845) | 1.83280824 |
75 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.83147990 |
76 | Premature ovarian failure (HP:0008209) | 1.82410680 |
77 | Morphological abnormality of the inner ear (HP:0011390) | 1.81313623 |
78 | Abnormal auditory evoked potentials (HP:0006958) | 1.81281871 |
79 | Autoamputation (HP:0001218) | 1.80816771 |
80 | Uterine neoplasm (HP:0010784) | 1.80530733 |
81 | Septo-optic dysplasia (HP:0100842) | 1.80243770 |
82 | Biliary tract neoplasm (HP:0100574) | 1.79492086 |
83 | Absent septum pellucidum (HP:0001331) | 1.78174786 |
84 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.77767828 |
85 | Leiomyosarcoma (HP:0100243) | 1.77162332 |
86 | Uterine leiomyosarcoma (HP:0002891) | 1.77162332 |
87 | Choanal atresia (HP:0000453) | 1.76438178 |
88 | CNS hypomyelination (HP:0003429) | 1.76289814 |
89 | Gastrointestinal carcinoma (HP:0002672) | 1.75187093 |
90 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.75187093 |
91 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.74932706 |
92 | Abnormality of the septum pellucidum (HP:0007375) | 1.74857209 |
93 | Sparse eyelashes (HP:0000653) | 1.74202190 |
94 | Megaloblastic anemia (HP:0001889) | 1.74148600 |
95 | Concave nail (HP:0001598) | 1.73941278 |
96 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.73834329 |
97 | Diastasis recti (HP:0001540) | 1.73796943 |
98 | Abnormality of the columella (HP:0009929) | 1.73173351 |
99 | Chromsome breakage (HP:0040012) | 1.72603055 |
100 | Atresia of the external auditory canal (HP:0000413) | 1.72327876 |
101 | Hypoglycemic seizures (HP:0002173) | 1.72040963 |
102 | Cafe-au-lait spot (HP:0000957) | 1.72000307 |
103 | Buphthalmos (HP:0000557) | 1.70900548 |
104 | Fatigue (HP:0012378) | 1.70752875 |
105 | Spastic gait (HP:0002064) | 1.70665085 |
106 | Glossoptosis (HP:0000162) | 1.70346686 |
107 | Abnormality of chromosome segregation (HP:0002916) | 1.70297511 |
108 | Abnormality of the renal collecting system (HP:0004742) | 1.70258831 |
109 | Abnormal number of incisors (HP:0011064) | 1.69962932 |
110 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.69632557 |
111 | Neoplasm of the oral cavity (HP:0100649) | 1.69293180 |
112 | Sparse lateral eyebrow (HP:0005338) | 1.68696359 |
113 | Ectopic kidney (HP:0000086) | 1.68500251 |
114 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.68394666 |
115 | Generalized hypotonia (HP:0001290) | 1.67973502 |
116 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.67826862 |
117 | Absent eyelashes (HP:0000561) | 1.67648308 |
118 | Oligodactyly (HP:0012165) | 1.67568981 |
119 | Cupped ear (HP:0000378) | 1.66541676 |
120 | Missing ribs (HP:0000921) | 1.66196371 |
121 | Deviation of the thumb (HP:0009603) | 1.65544966 |
122 | Hypoglycemic coma (HP:0001325) | 1.65067723 |
123 | Entropion (HP:0000621) | 1.64992453 |
124 | Intestinal atresia (HP:0011100) | 1.64620744 |
125 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.64364779 |
126 | Decreased lacrimation (HP:0000633) | 1.64251067 |
127 | Small intestinal stenosis (HP:0012848) | 1.64145735 |
128 | Duodenal stenosis (HP:0100867) | 1.64145735 |
129 | Absent epiphyses (HP:0010577) | 1.64059456 |
130 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.64059456 |
131 | Supernumerary spleens (HP:0009799) | 1.63964771 |
132 | Abnormality of homocysteine metabolism (HP:0010919) | 1.63816429 |
133 | Homocystinuria (HP:0002156) | 1.63816429 |
134 | Gastrointestinal atresia (HP:0002589) | 1.62779873 |
135 | Macroorchidism (HP:0000053) | 1.62669649 |
136 | Abnormality of the labia majora (HP:0012881) | 1.62222074 |
137 | Abnormal lung lobation (HP:0002101) | 1.61739853 |
138 | Split foot (HP:0001839) | 1.61636824 |
139 | Proximal tubulopathy (HP:0000114) | 1.61182846 |
140 | Absent eyebrow (HP:0002223) | 1.60634257 |
141 | Small epiphyses (HP:0010585) | 1.60594813 |
142 | Curly hair (HP:0002212) | 1.60346049 |
143 | Relative macrocephaly (HP:0004482) | 1.60104248 |
144 | Long nose (HP:0003189) | 1.59168589 |
145 | Ankle clonus (HP:0011448) | 1.58931152 |
146 | Large earlobe (HP:0009748) | 1.56575205 |
147 | Patellar aplasia (HP:0006443) | 1.56238277 |
148 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.55295631 |
149 | Carpal bone hypoplasia (HP:0001498) | 1.54632836 |
150 | Neurofibrillary tangles (HP:0002185) | 1.54126802 |
151 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.52676964 |
152 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.52157736 |
153 | Oligodactyly (hands) (HP:0001180) | 1.52087611 |
154 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.49271435 |
155 | Facial hemangioma (HP:0000329) | 1.47020383 |
156 | Premature rupture of membranes (HP:0001788) | 1.46823238 |
157 | Mild short stature (HP:0003502) | 1.46175558 |
158 | Mutism (HP:0002300) | 1.45940836 |
159 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.45404852 |
160 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.45404852 |
161 | Single umbilical artery (HP:0001195) | 1.45404852 |
162 | Abnormality of the umbilical cord (HP:0010881) | 1.43668288 |
163 | Premature graying of hair (HP:0002216) | 1.42879584 |
164 | Dysmetria (HP:0001310) | 1.42591403 |
165 | Depressed nasal tip (HP:0000437) | 1.41862604 |
166 | Proximal placement of thumb (HP:0009623) | 1.41269076 |
167 | Broad alveolar ridges (HP:0000187) | 1.40005338 |
168 | Bowel incontinence (HP:0002607) | 1.39260434 |
169 | Abnormal large intestine physiology (HP:0012700) | 1.38881297 |
170 | Coronal craniosynostosis (HP:0004440) | 1.37377223 |
171 | Heterochromia iridis (HP:0001100) | 1.37236055 |
172 | Synostosis involving the elbow (HP:0003938) | 1.36211481 |
173 | Humeroradial synostosis (HP:0003041) | 1.36211481 |
174 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.36082048 |
175 | Myokymia (HP:0002411) | 1.36075150 |
176 | Supernumerary ribs (HP:0005815) | 1.35592050 |
177 | Nemaline bodies (HP:0003798) | 1.34997666 |
178 | Rib fusion (HP:0000902) | 1.34944155 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STK39 | 3.63376073 |
2 | NEK1 | 3.26585404 |
3 | PRPF4B | 2.86379871 |
4 | BUB1 | 2.85788276 |
5 | BCR | 2.78025303 |
6 | PNCK | 2.52620648 |
7 | MKNK1 | 2.50425063 |
8 | WEE1 | 2.42235429 |
9 | OXSR1 | 2.31841152 |
10 | CAMK1G | 2.13892672 |
11 | TESK2 | 2.10325731 |
12 | CDK12 | 2.10116252 |
13 | STK10 | 1.95505221 |
14 | TAF1 | 1.95469748 |
15 | CDK19 | 1.91404077 |
16 | PBK | 1.86538844 |
17 | CASK | 1.84212996 |
18 | CAMK1D | 1.82816721 |
19 | CLK1 | 1.81562941 |
20 | MKNK2 | 1.75597845 |
21 | MAPKAPK5 | 1.69818218 |
22 | EPHB1 | 1.68517081 |
23 | BRAF | 1.64286615 |
24 | UHMK1 | 1.62520410 |
25 | LIMK1 | 1.62156043 |
26 | NEK6 | 1.57454216 |
27 | TNIK | 1.55128162 |
28 | EPHA4 | 1.52956806 |
29 | TSSK6 | 1.52644992 |
30 | LATS1 | 1.49831478 |
31 | SRPK1 | 1.47534787 |
32 | CDC7 | 1.43416181 |
33 | PLK3 | 1.41497306 |
34 | PLK2 | 1.40096824 |
35 | MARK3 | 1.35665921 |
36 | TYRO3 | 1.32106803 |
37 | EIF2AK1 | 1.30642347 |
38 | NUAK1 | 1.29755780 |
39 | MST4 | 1.29184469 |
40 | STK4 | 1.26698160 |
41 | LATS2 | 1.26069858 |
42 | DYRK2 | 1.25310154 |
43 | TRIM28 | 1.24198075 |
44 | EEF2K | 1.21995536 |
45 | BRD4 | 1.13456745 |
46 | ICK | 1.13184806 |
47 | CDK14 | 1.12684650 |
48 | PLK4 | 1.09984459 |
49 | BRSK2 | 1.07855369 |
50 | FGFR2 | 1.05914528 |
51 | NEK2 | 1.02858631 |
52 | MET | 1.01933891 |
53 | EPHA2 | 1.01720066 |
54 | FGR | 1.01263503 |
55 | EIF2AK2 | 1.00121279 |
56 | RPS6KB2 | 0.96469885 |
57 | DYRK3 | 0.95814231 |
58 | NLK | 0.95569009 |
59 | CDK7 | 0.93435739 |
60 | MARK1 | 0.93215983 |
61 | CSNK1G3 | 0.93168588 |
62 | WNK1 | 0.93143768 |
63 | KSR1 | 0.91074964 |
64 | STK24 | 0.91024296 |
65 | MAP3K12 | 0.90410632 |
66 | CSNK1A1L | 0.88889447 |
67 | PRKD3 | 0.85394631 |
68 | AURKB | 0.84707132 |
69 | AURKA | 0.83375811 |
70 | PLK1 | 0.81073711 |
71 | MAP3K11 | 0.80906139 |
72 | VRK1 | 0.80376045 |
73 | ALK | 0.80368700 |
74 | CDK18 | 0.79734250 |
75 | MINK1 | 0.78336961 |
76 | MAP3K8 | 0.78005504 |
77 | SMG1 | 0.77244705 |
78 | STK16 | 0.76664674 |
79 | FES | 0.75977636 |
80 | ARAF | 0.75853025 |
81 | CDK15 | 0.74686661 |
82 | NTRK3 | 0.73729567 |
83 | ACVR1B | 0.73662317 |
84 | DMPK | 0.73493728 |
85 | ROCK2 | 0.73461021 |
86 | CDK11A | 0.71183880 |
87 | SIK3 | 0.69577074 |
88 | CHEK1 | 0.68277814 |
89 | BMPR1B | 0.68132969 |
90 | PKN1 | 0.67771810 |
91 | FGFR1 | 0.66408250 |
92 | NME2 | 0.65041639 |
93 | CSNK1G1 | 0.64828696 |
94 | TTK | 0.62763787 |
95 | AKT3 | 0.61895414 |
96 | KSR2 | 0.61388079 |
97 | CAMK2B | 0.60633569 |
98 | ERBB3 | 0.60256353 |
99 | ERBB4 | 0.59264022 |
100 | NTRK1 | 0.56346472 |
101 | MAPK13 | 0.54850499 |
102 | PIM2 | 0.54722325 |
103 | RPS6KA5 | 0.53483013 |
104 | RAF1 | 0.51357036 |
105 | PIM1 | 0.50937471 |
106 | STK3 | 0.49015154 |
107 | CSNK1E | 0.48965150 |
108 | STK11 | 0.48799351 |
109 | CDK1 | 0.48510110 |
110 | TGFBR1 | 0.48389978 |
111 | PAK1 | 0.48314372 |
112 | YES1 | 0.47941369 |
113 | BRSK1 | 0.46916322 |
114 | MAPK10 | 0.46795893 |
115 | CSNK1G2 | 0.46450620 |
116 | CAMK2D | 0.46206860 |
117 | NME1 | 0.45905574 |
118 | CDK2 | 0.45131155 |
119 | CCNB1 | 0.45067176 |
120 | CDK6 | 0.44871898 |
121 | CSNK1D | 0.44640843 |
122 | CHEK2 | 0.44395278 |
123 | ATM | 0.43929737 |
124 | MTOR | 0.43745647 |
125 | MAP3K10 | 0.42589674 |
126 | MAP3K9 | 0.41494129 |
127 | CDK5 | 0.41398233 |
128 | ATR | 0.40237639 |
129 | IRAK2 | 0.40042576 |
130 | SGK3 | 0.39610888 |
131 | VRK2 | 0.39337445 |
132 | MELK | 0.39154254 |
133 | CDK3 | 0.38447158 |
134 | MOS | 0.38310395 |
135 | MAP3K13 | 0.37426999 |
136 | CAMK2A | 0.36584142 |
137 | EIF2AK3 | 0.36499838 |
138 | AKT2 | 0.35907773 |
139 | SCYL2 | 0.35696179 |
140 | PTK2 | 0.34895387 |
141 | SGK2 | 0.34500738 |
142 | CSNK2A2 | 0.34381848 |
143 | PASK | 0.34200514 |
144 | CDK4 | 0.33791486 |
145 | MAP3K6 | 0.33536336 |
146 | MAP3K14 | 0.33194939 |
147 | CDK9 | 0.33110476 |
148 | DYRK1A | 0.30688418 |
149 | WNK3 | 0.30565877 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.47899007 |
2 | RNA polymerase_Homo sapiens_hsa03020 | 2.33978458 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.18429155 |
4 | Spliceosome_Homo sapiens_hsa03040 | 2.03249198 |
5 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.90327519 |
6 | DNA replication_Homo sapiens_hsa03030 | 1.79391341 |
7 | Basal transcription factors_Homo sapiens_hsa03022 | 1.76215463 |
8 | Proteasome_Homo sapiens_hsa03050 | 1.62589867 |
9 | RNA transport_Homo sapiens_hsa03013 | 1.60964839 |
10 | Mismatch repair_Homo sapiens_hsa03430 | 1.60235803 |
11 | Cell cycle_Homo sapiens_hsa04110 | 1.58694010 |
12 | Homologous recombination_Homo sapiens_hsa03440 | 1.52155838 |
13 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.50865559 |
14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.41068806 |
15 | * mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.37166882 |
16 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.36550346 |
17 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.35177715 |
18 | Base excision repair_Homo sapiens_hsa03410 | 1.35076476 |
19 | Axon guidance_Homo sapiens_hsa04360 | 1.33006164 |
20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.31111126 |
21 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.28809023 |
22 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.24703148 |
23 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.22467389 |
24 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.21392240 |
25 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.16862763 |
26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16827359 |
27 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.15054126 |
28 | Shigellosis_Homo sapiens_hsa05131 | 1.14269453 |
29 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.14109621 |
30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13654870 |
31 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.07729709 |
32 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.07039714 |
33 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.06812479 |
34 | RNA degradation_Homo sapiens_hsa03018 | 1.05415276 |
35 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.04141767 |
36 | Long-term depression_Homo sapiens_hsa04730 | 1.03702583 |
37 | * Hippo signaling pathway_Homo sapiens_hsa04390 | 1.02927806 |
38 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.99082162 |
39 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.98145676 |
40 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.96426450 |
41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.96136762 |
42 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.95678371 |
43 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.95316625 |
44 | Ribosome_Homo sapiens_hsa03010 | 0.94297786 |
45 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.93497670 |
46 | * Tight junction_Homo sapiens_hsa04530 | 0.92641626 |
47 | * Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.92033145 |
48 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91849954 |
49 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.90005036 |
50 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.83912437 |
51 | Thyroid cancer_Homo sapiens_hsa05216 | 0.81754822 |
52 | Huntingtons disease_Homo sapiens_hsa05016 | 0.80734469 |
53 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.80006672 |
54 | Salmonella infection_Homo sapiens_hsa05132 | 0.78800656 |
55 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.78444869 |
56 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.78111358 |
57 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.77764927 |
58 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.75536577 |
59 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.74474432 |
60 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.74296979 |
61 | Circadian rhythm_Homo sapiens_hsa04710 | 0.74107204 |
62 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.74006284 |
63 | Endometrial cancer_Homo sapiens_hsa05213 | 0.73459266 |
64 | * Dopaminergic synapse_Homo sapiens_hsa04728 | 0.72876858 |
65 | Gap junction_Homo sapiens_hsa04540 | 0.72782092 |
66 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.72351959 |
67 | Protein export_Homo sapiens_hsa03060 | 0.71537174 |
68 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.71262362 |
69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.69901959 |
70 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.69773106 |
71 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.68895304 |
72 | Allograft rejection_Homo sapiens_hsa05330 | 0.68549278 |
73 | Bladder cancer_Homo sapiens_hsa05219 | 0.67756224 |
74 | Long-term potentiation_Homo sapiens_hsa04720 | 0.67278652 |
75 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.67140650 |
76 | Melanogenesis_Homo sapiens_hsa04916 | 0.66707048 |
77 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.64725498 |
78 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64353755 |
79 | Pathways in cancer_Homo sapiens_hsa05200 | 0.64162149 |
80 | Endocytosis_Homo sapiens_hsa04144 | 0.63428766 |
81 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62749496 |
82 | Cocaine addiction_Homo sapiens_hsa05030 | 0.61979137 |
83 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.61432561 |
84 | Purine metabolism_Homo sapiens_hsa00230 | 0.61226497 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.60664057 |
86 | Morphine addiction_Homo sapiens_hsa05032 | 0.60453445 |
87 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.60401242 |
88 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59871400 |
89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.59232172 |
90 | Parkinsons disease_Homo sapiens_hsa05012 | 0.58667437 |
91 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.58503052 |
92 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.58437278 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.57784700 |
94 | Prostate cancer_Homo sapiens_hsa05215 | 0.56936078 |
95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.56165555 |
96 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.55232560 |
97 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.55174307 |
98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54538326 |
99 | HTLV-I infection_Homo sapiens_hsa05166 | 0.54369710 |
100 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.53983173 |
101 | Viral myocarditis_Homo sapiens_hsa05416 | 0.53487445 |
102 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.53295151 |
103 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.53166005 |
104 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.52539169 |
105 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.52309815 |
106 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52266276 |
107 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.52022758 |
108 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52008139 |
109 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.51762738 |
110 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.51700475 |
111 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51468426 |
112 | Melanoma_Homo sapiens_hsa05218 | 0.51130818 |
113 | Adherens junction_Homo sapiens_hsa04520 | 0.50602174 |
114 | Glioma_Homo sapiens_hsa05214 | 0.50395101 |
115 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50357944 |
116 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.50240332 |
117 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.49988255 |
118 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.49477511 |
119 | Asthma_Homo sapiens_hsa05310 | 0.49453987 |
120 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.47569366 |
121 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.46415295 |
122 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.45800891 |
123 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.45533029 |
124 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45438564 |
125 | Hepatitis B_Homo sapiens_hsa05161 | 0.45136495 |
126 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.44918843 |
127 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.43432314 |
128 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.42925095 |
129 | Lysine degradation_Homo sapiens_hsa00310 | 0.42634041 |
130 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39333435 |
131 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.37763675 |
132 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.35676633 |
133 | * Hepatitis C_Homo sapiens_hsa05160 | 0.34541820 |
134 | Carbon metabolism_Homo sapiens_hsa01200 | 0.33271915 |
135 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.31620462 |
136 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.31351785 |
137 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.30047811 |
138 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.29567002 |
139 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28906039 |
140 | Alzheimers disease_Homo sapiens_hsa05010 | 0.28619393 |
141 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27237149 |
142 | Apoptosis_Homo sapiens_hsa04210 | 0.27034288 |
143 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.26760045 |
144 | Measles_Homo sapiens_hsa05162 | 0.25817487 |
145 | * AMPK signaling pathway_Homo sapiens_hsa04152 | 0.24681293 |
146 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21781520 |