PPP3CA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ionotropic glutamate receptor signaling pathway (GO:0035235)5.52151845
2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.30152689
3vocalization behavior (GO:0071625)5.28203926
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.27065817
5glutamate receptor signaling pathway (GO:0007215)5.22213425
6regulation of short-term neuronal synaptic plasticity (GO:0048172)5.16967210
7locomotory exploration behavior (GO:0035641)5.02563762
8protein localization to synapse (GO:0035418)4.92938339
9regulation of glutamate receptor signaling pathway (GO:1900449)4.88639232
10regulation of long-term neuronal synaptic plasticity (GO:0048169)4.72547082
11neuronal action potential propagation (GO:0019227)4.71301401
12synaptic vesicle exocytosis (GO:0016079)4.67587003
13positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.58986730
14neuron cell-cell adhesion (GO:0007158)4.49960007
15exploration behavior (GO:0035640)4.47155280
16synaptic transmission, glutamatergic (GO:0035249)4.47113986
17neuron-neuron synaptic transmission (GO:0007270)4.44649251
18regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.42357783
19regulation of dendritic spine morphogenesis (GO:0061001)4.39204889
20regulation of neuronal synaptic plasticity (GO:0048168)4.37979079
21regulation of synaptic vesicle exocytosis (GO:2000300)4.23441931
22gamma-aminobutyric acid signaling pathway (GO:0007214)4.21900272
23glutamate secretion (GO:0014047)4.19105331
24synaptic vesicle maturation (GO:0016188)4.16381459
25neuron recognition (GO:0008038)4.07689377
26positive regulation of dendritic spine morphogenesis (GO:0061003)4.07368749
27long-term memory (GO:0007616)4.03261783
28regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.01475375
29behavioral fear response (GO:0001662)3.98390761
30behavioral defense response (GO:0002209)3.98390761
31synaptic vesicle docking involved in exocytosis (GO:0016081)3.97145209
32regulation of synaptic plasticity (GO:0048167)3.96427270
33* regulation of excitatory postsynaptic membrane potential (GO:0060079)3.96329293
34long-term synaptic potentiation (GO:0060291)3.94743567
35regulation of synaptic vesicle transport (GO:1902803)3.92736793
36proline transport (GO:0015824)3.91155684
37G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.91036496
38neurotransmitter-gated ion channel clustering (GO:0072578)3.87836047
39transmission of nerve impulse (GO:0019226)3.82033840
40G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.81836360
41membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.80136402
42positive regulation of synapse maturation (GO:0090129)3.79734410
43regulation of synapse structural plasticity (GO:0051823)3.77000630
44regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.72956023
45* regulation of postsynaptic membrane potential (GO:0060078)3.72139238
46fear response (GO:0042596)3.71854986
47regulation of glutamate secretion (GO:0014048)3.70826196
48regulation of dendritic spine development (GO:0060998)3.70197233
49response to histamine (GO:0034776)3.68998847
50axonal fasciculation (GO:0007413)3.67668417
51negative regulation of synaptic transmission, GABAergic (GO:0032229)3.67645904
52positive regulation of neurotransmitter secretion (GO:0001956)3.63361350
53regulation of synaptic transmission, glutamatergic (GO:0051966)3.57064514
54cellular potassium ion homeostasis (GO:0030007)3.57023699
55positive regulation of dendritic spine development (GO:0060999)3.56582780
56dendritic spine morphogenesis (GO:0060997)3.55307187
57neurotransmitter secretion (GO:0007269)3.53317166
58positive regulation of membrane potential (GO:0045838)3.52208714
59synaptic transmission, dopaminergic (GO:0001963)3.51062968
60long term synaptic depression (GO:0060292)3.49646142
61regulation of female receptivity (GO:0045924)3.48266223
62presynaptic membrane assembly (GO:0097105)3.45485312
63synaptic vesicle endocytosis (GO:0048488)3.44679291
64dendritic spine organization (GO:0097061)3.44259467
65behavioral response to cocaine (GO:0048148)3.43657960
66regulation of neurotransmitter levels (GO:0001505)3.42830487
67learning (GO:0007612)3.41407543
68regulation of vesicle fusion (GO:0031338)3.40619233
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.39132724
70sodium ion export (GO:0071436)3.36186872
71neurotransmitter uptake (GO:0001504)3.33228959
72cerebellar granule cell differentiation (GO:0021707)3.31739827
73positive regulation of neurotransmitter transport (GO:0051590)3.29691353
74innervation (GO:0060384)3.28511332
75presynaptic membrane organization (GO:0097090)3.24442986
76female mating behavior (GO:0060180)3.23338607
77glial cell proliferation (GO:0014009)3.23079372
78layer formation in cerebral cortex (GO:0021819)3.20840861
79neuromuscular process controlling balance (GO:0050885)3.19766977
80chemosensory behavior (GO:0007635)3.19542131
81negative regulation of amino acid transport (GO:0051956)3.19233989
82postsynaptic membrane organization (GO:0001941)3.16920436
83* membrane depolarization (GO:0051899)3.15740352
84positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.15152657
85regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.13693666
86serotonin metabolic process (GO:0042428)3.10611570
87regulation of neurotransmitter transport (GO:0051588)3.10297930
88positive regulation of synaptic transmission, GABAergic (GO:0032230)3.10180837
89membrane depolarization during action potential (GO:0086010)3.07373848
90vesicle transport along microtubule (GO:0047496)3.06063956
91negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.05025451
92phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.04173396
93gamma-aminobutyric acid transport (GO:0015812)3.03616206
94regulation of neurotransmitter secretion (GO:0046928)3.02733382
95positive regulation of synaptic transmission (GO:0050806)3.02067515
96striatum development (GO:0021756)3.01963317
97detection of calcium ion (GO:0005513)2.99568561
98regulation of cell communication by electrical coupling (GO:0010649)2.98605923
99neurotransmitter transport (GO:0006836)2.98292793
100* regulation of synaptic transmission (GO:0050804)2.98194897
101regulation of synapse maturation (GO:0090128)2.98152084
102negative regulation of dendrite development (GO:2000171)2.97647371
103cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.96291069
104synaptic transmission (GO:0007268)2.94989680
105nerve growth factor signaling pathway (GO:0038180)2.92139882
106potassium ion homeostasis (GO:0055075)2.92011412
107L-amino acid import (GO:0043092)2.90764336
108regulation of calcium ion-dependent exocytosis (GO:0017158)2.90099181
109cochlea development (GO:0090102)2.90083409
110learning or memory (GO:0007611)2.89552500
111regulation of sodium ion transmembrane transporter activity (GO:2000649)2.88990589
112activation of protein kinase A activity (GO:0034199)2.88945504
113negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.88880081
114negative regulation of translation, ncRNA-mediated (GO:0040033)2.88880081
115regulation of translation, ncRNA-mediated (GO:0045974)2.88880081
116primary amino compound metabolic process (GO:1901160)2.88659713
117negative regulation of dendrite morphogenesis (GO:0050774)2.87936637
118associative learning (GO:0008306)2.87419408
119potassium ion import (GO:0010107)2.86621171
120glycosphingolipid biosynthetic process (GO:0006688)2.84855914
121C4-dicarboxylate transport (GO:0015740)2.83787699
122regulation of neurotransmitter uptake (GO:0051580)2.81094921
123neuromuscular process controlling posture (GO:0050884)2.78254571
124neuromuscular synaptic transmission (GO:0007274)2.77327224
125startle response (GO:0001964)2.76778475
126regulation of voltage-gated calcium channel activity (GO:1901385)2.72310932
127auditory behavior (GO:0031223)2.68620795
128righting reflex (GO:0060013)2.68155464
129positive regulation of protein autophosphorylation (GO:0031954)2.67294236
130cardiac conduction (GO:0061337)2.67082836
131response to gravity (GO:0009629)2.65254255
132establishment of synaptic vesicle localization (GO:0097480)2.64471871
133synaptic vesicle transport (GO:0048489)2.64471871
134adaptation of signaling pathway (GO:0023058)2.63947411
135cerebellar Purkinje cell differentiation (GO:0021702)2.63702711
136positive regulation of vesicle fusion (GO:0031340)2.62667200
137detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.62547874
138regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.60317969
139cellular potassium ion transport (GO:0071804)2.60085510
140potassium ion transmembrane transport (GO:0071805)2.60085510

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.32820444
2GBX2_23144817_ChIP-Seq_PC3_Human4.09367960
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.20226513
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.17601453
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.15055205
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.81511764
7* RARB_27405468_Chip-Seq_BRAIN_Mouse2.72410864
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.69941687
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.69941687
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.63119250
11* REST_21632747_ChIP-Seq_MESCs_Mouse2.57405477
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.53877418
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.53203720
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.49971890
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42101791
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.40099318
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.33099367
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.23202858
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.20461296
20TAF15_26573619_Chip-Seq_HEK293_Human2.17924116
21DROSHA_22980978_ChIP-Seq_HELA_Human2.16850031
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.15308953
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.13138024
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09995457
25CTBP1_25329375_ChIP-Seq_LNCAP_Human1.99048880
26* REST_18959480_ChIP-ChIP_MESCs_Mouse1.96884822
27AR_21572438_ChIP-Seq_LNCaP_Human1.90689976
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89299613
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.89046945
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84777528
31* SMAD4_21799915_ChIP-Seq_A2780_Human1.80863284
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.78969499
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.77108232
34* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77087041
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.67343176
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65942859
37* P300_19829295_ChIP-Seq_ESCs_Human1.65405285
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.63248100
39EWS_26573619_Chip-Seq_HEK293_Human1.61959028
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.58472983
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57739338
42ZNF274_21170338_ChIP-Seq_K562_Hela1.53037130
43NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51095580
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47250804
45NR3C1_23031785_ChIP-Seq_PC12_Mouse1.45853201
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.44900487
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44793828
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.41683354
49VDR_22108803_ChIP-Seq_LS180_Human1.40277135
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39950168
51* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39944998
52FUS_26573619_Chip-Seq_HEK293_Human1.39278052
53SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38726130
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38488261
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37734705
56TP53_16413492_ChIP-PET_HCT116_Human1.37106546
57* AR_25329375_ChIP-Seq_VCAP_Human1.35590210
58ERG_21242973_ChIP-ChIP_JURKAT_Human1.35105845
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.34689212
60IGF1R_20145208_ChIP-Seq_DFB_Human1.34086577
61GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.32287457
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31659108
63* P53_22387025_ChIP-Seq_ESCs_Mouse1.30745564
64* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30687210
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.28674373
66SMAD_19615063_ChIP-ChIP_OVARY_Human1.28422085
67* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27578915
68* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26692863
69FLI1_21867929_ChIP-Seq_TH2_Mouse1.26446759
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.26413303
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26280080
72* STAT3_23295773_ChIP-Seq_U87_Human1.26048429
73EZH2_27294783_Chip-Seq_NPCs_Mouse1.25689096
74* CBP_20019798_ChIP-Seq_JUKART_Human1.22920655
75* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.22920655
76* TCF4_22108803_ChIP-Seq_LS180_Human1.22464023
77RING1B_27294783_Chip-Seq_ESCs_Mouse1.20160857
78KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18988759
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18632074
80PRDM14_20953172_ChIP-Seq_ESCs_Human1.18483672
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18370171
82NANOG_19829295_ChIP-Seq_ESCs_Human1.16774645
83SOX2_19829295_ChIP-Seq_ESCs_Human1.16774645
84CDX2_19796622_ChIP-Seq_MESCs_Mouse1.15990273
85TP53_18474530_ChIP-ChIP_U2OS_Human1.15464228
86NFE2_27457419_Chip-Seq_LIVER_Mouse1.14843847
87* CMYC_18555785_Chip-Seq_ESCs_Mouse1.14839444
88* AR_19668381_ChIP-Seq_PC3_Human1.14551956
89TCF4_23295773_ChIP-Seq_U87_Human1.14024720
90TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.13645684
91* SMAD4_21741376_ChIP-Seq_EPCs_Human1.13618946
92FOXM1_26456572_ChIP-Seq_MCF-7_Human1.13327704
93NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12712528
94NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12712528
95CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11648289
96* E2F1_18555785_Chip-Seq_ESCs_Mouse1.11026181
97PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10662986
98* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09976010
99CRX_20693478_ChIP-Seq_RETINA_Mouse1.09846294
100PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09660818
101RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09639284
102* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08828191
103* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08665616
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08627738
105RNF2_27304074_Chip-Seq_NSC_Mouse1.07240481
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.07016582
107P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06425160
108* RUNX2_22187159_ChIP-Seq_PCA_Human1.05872412
109* ARNT_22903824_ChIP-Seq_MCF-7_Human1.04711146
110BCAT_22108803_ChIP-Seq_LS180_Human1.04036829
111RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03716478
112RING1B_27294783_Chip-Seq_NPCs_Mouse1.03350173
113JUN_21703547_ChIP-Seq_K562_Human1.02254692
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02132021
115AHR_22903824_ChIP-Seq_MCF-7_Human1.00879082
116TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00090627
117POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00090627
118* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99718860
119SMAD3_21741376_ChIP-Seq_HESCs_Human0.99675904
120* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98581381
121* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98234895
122* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96989162
123* NANOG_18555785_Chip-Seq_ESCs_Mouse0.96925057
124RXR_22108803_ChIP-Seq_LS180_Human0.93654553
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92256693
126ER_23166858_ChIP-Seq_MCF-7_Human0.91204426
127VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91056718
128ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90141911
129TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90007833
130RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89908216

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.91591336
2MP0003880_abnormal_central_pattern6.08865181
3MP0003635_abnormal_synaptic_transmissio4.27353380
4MP0004270_analgesia3.86137983
5MP0009745_abnormal_behavioral_response3.69153647
6MP0002063_abnormal_learning/memory/cond3.58655174
7MP0001968_abnormal_touch/_nociception3.23965864
8MP0002822_catalepsy3.21593628
9MP0002064_seizures3.12866729
10MP0002572_abnormal_emotion/affect_behav2.92802309
11MP0002736_abnormal_nociception_after2.85592051
12MP0002735_abnormal_chemical_nociception2.76933480
13MP0002272_abnormal_nervous_system2.73396050
14MP0009046_muscle_twitch2.65931655
15MP0001501_abnormal_sleep_pattern2.58668604
16MP0001486_abnormal_startle_reflex2.42847563
17MP0001440_abnormal_grooming_behavior2.38150109
18MP0002734_abnormal_mechanical_nocicepti2.28225321
19MP0008877_abnormal_DNA_methylation2.27802266
20MP0003329_amyloid_beta_deposits2.09709499
21MP0002067_abnormal_sensory_capabilities1.95017511
22MP0005423_abnormal_somatic_nervous1.90695774
23MP0002733_abnormal_thermal_nociception1.88811255
24MP0001970_abnormal_pain_threshold1.86408382
25MP0001188_hyperpigmentation1.83647255
26MP0000778_abnormal_nervous_system1.77916152
27MP0001529_abnormal_vocalization1.76523634
28MP0002184_abnormal_innervation1.76342776
29MP0006276_abnormal_autonomic_nervous1.75437750
30MP0002909_abnormal_adrenal_gland1.75082925
31MP0009780_abnormal_chondrocyte_physiolo1.64045608
32MP0004924_abnormal_behavior1.63303907
33MP0005386_behavior/neurological_phenoty1.63303907
34MP0008569_lethality_at_weaning1.60033092
35MP0002557_abnormal_social/conspecific_i1.59453590
36MP0004811_abnormal_neuron_physiology1.50653416
37MP0002837_dystrophic_cardiac_calcinosis1.43140553
38MP0003879_abnormal_hair_cell1.42312115
39MP0000955_abnormal_spinal_cord1.40465210
40MP0004858_abnormal_nervous_system1.40113187
41MP0005409_darkened_coat_color1.38651068
42MP0004145_abnormal_muscle_electrophysio1.38317337
43MP0002066_abnormal_motor_capabilities/c1.35945335
44MP0005646_abnormal_pituitary_gland1.32992824
45MP0001984_abnormal_olfaction1.32129874
46MP0002882_abnormal_neuron_morphology1.29576096
47MP0003633_abnormal_nervous_system1.26332000
48MP0001905_abnormal_dopamine_level1.24778374
49MP0003787_abnormal_imprinting1.24637789
50MP0006072_abnormal_retinal_apoptosis1.15565255
51MP0001502_abnormal_circadian_rhythm1.11385061
52MP0004147_increased_porphyrin_level1.11372248
53MP0004043_abnormal_pH_regulation1.10994751
54MP0004885_abnormal_endolymph1.09308504
55MP0003631_nervous_system_phenotype1.08479920
56MP0000569_abnormal_digit_pigmentation1.07892110
57MP0004484_altered_response_of1.07773439
58MP0000427_abnormal_hair_cycle1.03966096
59MP0003121_genomic_imprinting1.02893458
60MP0000604_amyloidosis1.01934718
61MP0005253_abnormal_eye_physiology1.00939532
62MP0002876_abnormal_thyroid_physiology1.00168698
63MP0003011_delayed_dark_adaptation0.99149875
64MP0005187_abnormal_penis_morphology0.98407860
65MP0008874_decreased_physiological_sensi0.98199509
66MP0004510_myositis0.96534592
67* MP0002152_abnormal_brain_morphology0.96281344
68MP0010386_abnormal_urinary_bladder0.95144213
69MP0003123_paternal_imprinting0.94735399
70MP0000751_myopathy0.92462867
71MP0002102_abnormal_ear_morphology0.92209316
72MP0004142_abnormal_muscle_tone0.91627941
73MP0001986_abnormal_taste_sensitivity0.90935822
74MP0004085_abnormal_heartbeat0.90647081
75MP0008872_abnormal_physiological_respon0.90557039
76MP0002229_neurodegeneration0.90192627
77MP0005645_abnormal_hypothalamus_physiol0.89775238
78MP0002069_abnormal_eating/drinking_beha0.89754459
79MP0005535_abnormal_body_temperature0.89578017
80MP0008875_abnormal_xenobiotic_pharmacok0.89468447
81MP0003075_altered_response_to0.88237663
82MP0004742_abnormal_vestibular_system0.85651985
83MP0004215_abnormal_myocardial_fiber0.84079234
84MP0005551_abnormal_eye_electrophysiolog0.82125108
85MP0005367_renal/urinary_system_phenotyp0.81573802
86MP0000516_abnormal_urinary_system0.81573802
87MP0001963_abnormal_hearing_physiology0.81467436
88MP0003632_abnormal_nervous_system0.76486517
89MP0003283_abnormal_digestive_organ0.75622651
90MP0000013_abnormal_adipose_tissue0.75179519
91MP0000920_abnormal_myelination0.73773878
92MP0003195_calcinosis0.73340624
93MP0006292_abnormal_olfactory_placode0.73058850
94MP0010234_abnormal_vibrissa_follicle0.72547700
95MP0001177_atelectasis0.72398340
96MP0002160_abnormal_reproductive_system0.71665321
97MP0001485_abnormal_pinna_reflex0.71489778
98MP0009379_abnormal_foot_pigmentation0.67809426
99MP0002752_abnormal_somatic_nervous0.67597684
100MP0001664_abnormal_digestion0.66755539
101MP0002751_abnormal_autonomic_nervous0.65963269
102MP0010678_abnormal_skin_adnexa0.65396538
103MP0003634_abnormal_glial_cell0.64599032
104MP0002638_abnormal_pupillary_reflex0.63903317
105MP0002234_abnormal_pharynx_morphology0.63761551
106MP0005394_taste/olfaction_phenotype0.62970135
107MP0005499_abnormal_olfactory_system0.62970135
108MP0004134_abnormal_chest_morphology0.61354327
109MP0005171_absent_coat_pigmentation0.60370040
110MP0005389_reproductive_system_phenotype0.60288578
111MP0003690_abnormal_glial_cell0.59852670
112MP0003137_abnormal_impulse_conducting0.57820456
113MP0002090_abnormal_vision0.57673692
114MP0003122_maternal_imprinting0.57299260
115MP0000631_abnormal_neuroendocrine_gland0.55825740
116MP0001919_abnormal_reproductive_system0.54532443
117MP0005595_abnormal_vascular_smooth0.54122478
118MP0005167_abnormal_blood-brain_barrier0.51436644
119MP0005620_abnormal_muscle_contractility0.51031133
120MP0000026_abnormal_inner_ear0.49698842
121* MP0001765_abnormal_ion_homeostasis0.49317705
122MP0001943_abnormal_respiration0.47863037
123MP0003861_abnormal_nervous_system0.43388798
124* MP0003956_abnormal_body_size0.43008425
125MP0010769_abnormal_survival0.42393945

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.28172596
2Myokymia (HP:0002411)6.73705780
3Focal seizures (HP:0007359)6.22509192
4Atonic seizures (HP:0010819)5.24105839
5Epileptic encephalopathy (HP:0200134)5.15743787
6Visual hallucinations (HP:0002367)5.13870883
7Hyperventilation (HP:0002883)4.80574602
8Absence seizures (HP:0002121)4.75642203
9Febrile seizures (HP:0002373)4.72651819
10Dialeptic seizures (HP:0011146)4.47753993
11Broad-based gait (HP:0002136)4.15854260
12Generalized tonic-clonic seizures (HP:0002069)4.02999253
13Progressive cerebellar ataxia (HP:0002073)3.83011393
14Cerebral inclusion bodies (HP:0100314)3.81733686
15Amblyopia (HP:0000646)3.79531102
16Supranuclear gaze palsy (HP:0000605)3.57787968
17Action tremor (HP:0002345)3.55020602
18Dysdiadochokinesis (HP:0002075)3.52459528
19Dysmetria (HP:0001310)3.46619545
20Gaze-evoked nystagmus (HP:0000640)3.46187015
21Neurofibrillary tangles (HP:0002185)3.44862419
22Poor eye contact (HP:0000817)3.39629561
23Limb dystonia (HP:0002451)3.38469664
24Truncal ataxia (HP:0002078)3.24083737
25Anxiety (HP:0000739)3.21464990
26Impaired vibration sensation in the lower limbs (HP:0002166)3.05613346
27Drooling (HP:0002307)3.05548579
28Excessive salivation (HP:0003781)3.05548579
29Depression (HP:0000716)3.04904196
30Abnormal social behavior (HP:0012433)3.04455335
31Impaired social interactions (HP:0000735)3.04455335
32Absent speech (HP:0001344)2.92127037
33Scanning speech (HP:0002168)2.81168509
34Neoplasm of the adrenal cortex (HP:0100641)2.78450837
35Hemiplegia (HP:0002301)2.71836279
36Hemiparesis (HP:0001269)2.70202906
37Stereotypic behavior (HP:0000733)2.68314207
38Impaired smooth pursuit (HP:0007772)2.68116000
39Abnormality of binocular vision (HP:0011514)2.67933536
40Diplopia (HP:0000651)2.67933536
41Hypothermia (HP:0002045)2.65019930
42Epileptiform EEG discharges (HP:0011182)2.64804229
43Progressive inability to walk (HP:0002505)2.62998366
44Postural instability (HP:0002172)2.62351008
45Delusions (HP:0000746)2.58039175
46Lower limb asymmetry (HP:0100559)2.57408619
47Urinary bladder sphincter dysfunction (HP:0002839)2.57308831
48Sensory axonal neuropathy (HP:0003390)2.52132403
49Abnormal eating behavior (HP:0100738)2.50042179
50Annular pancreas (HP:0001734)2.48243089
51Insidious onset (HP:0003587)2.47504790
52Termporal pattern (HP:0011008)2.47504790
53Inability to walk (HP:0002540)2.46079151
54Testicular atrophy (HP:0000029)2.43605160
55Abnormality of the lower motor neuron (HP:0002366)2.41127464
56Bradykinesia (HP:0002067)2.40811593
57Protruding tongue (HP:0010808)2.39171307
58Thickened helices (HP:0000391)2.38884777
59Cerebral hypomyelination (HP:0006808)2.37065315
60Hydroureter (HP:0000072)2.33567727
61Status epilepticus (HP:0002133)2.32637657
62EEG with generalized epileptiform discharges (HP:0011198)2.32356859
63Urinary urgency (HP:0000012)2.26780523
64Intention tremor (HP:0002080)2.21647131
65Pancreatic cysts (HP:0001737)2.20526533
66Dysmetric saccades (HP:0000641)2.19929105
67Exotropia (HP:0000577)2.18510959
68Agitation (HP:0000713)2.17773343
69Ankle clonus (HP:0011448)2.17410008
70Generalized myoclonic seizures (HP:0002123)2.16216255
71Ketoacidosis (HP:0001993)2.16058022
72Spastic gait (HP:0002064)2.14566862
73Psychosis (HP:0000709)2.13675415
74Abnormality of ocular smooth pursuit (HP:0000617)2.13389178
75Torticollis (HP:0000473)2.13332871
76Pancreatic fibrosis (HP:0100732)2.12619972
77Mutism (HP:0002300)2.11295165
78Genetic anticipation (HP:0003743)2.11178793
79Abnormality of salivation (HP:0100755)2.10963756
80Methylmalonic acidemia (HP:0002912)2.09477213
81Hamartoma of the eye (HP:0010568)2.09201849
82Lower limb amyotrophy (HP:0007210)2.09121517
83Impaired vibratory sensation (HP:0002495)2.08308131
84Hypsarrhythmia (HP:0002521)2.08221660
85Focal dystonia (HP:0004373)2.06317582
86Palpebral edema (HP:0100540)2.04693668
87Abnormality of the labia minora (HP:0012880)2.04605679
88Bundle branch block (HP:0011710)2.04157805
89Fetal akinesia sequence (HP:0001989)2.03653423
90Neoplasm of the adrenal gland (HP:0100631)2.00012732
91Blue irides (HP:0000635)1.99939211
92Gait ataxia (HP:0002066)1.99248551
93Dyskinesia (HP:0100660)1.98569746
94Rapidly progressive (HP:0003678)1.97111965
95Incomplete penetrance (HP:0003829)1.97081421
96Fair hair (HP:0002286)1.96640471
97Abnormality of the corticospinal tract (HP:0002492)1.95897386
98Astrocytoma (HP:0009592)1.94367551
99Abnormality of the astrocytes (HP:0100707)1.94367551
100Deep palmar crease (HP:0006191)1.94223746
101Megalencephaly (HP:0001355)1.92835071
102Hyperinsulinemic hypoglycemia (HP:0000825)1.92713082
103Progressive macrocephaly (HP:0004481)1.92671832
104Akinesia (HP:0002304)1.90899882
105Widely spaced teeth (HP:0000687)1.89980295
106Muscular hypotonia of the trunk (HP:0008936)1.88663700
107True hermaphroditism (HP:0010459)1.87490017
108Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.87138336
109Congenital stationary night blindness (HP:0007642)1.86905057
110Inappropriate behavior (HP:0000719)1.86046323
111Syncope (HP:0001279)1.85867225
112Nuclear cataract (HP:0100018)1.85857767
113Abolished electroretinogram (ERG) (HP:0000550)1.85216891
114Morphological abnormality of the pyramidal tract (HP:0002062)1.84833560
115Abnormality of secondary sexual hair (HP:0009888)1.84243197
116Abnormality of the axillary hair (HP:0100134)1.84243197
117Generalized hypopigmentation of hair (HP:0011358)1.84058553
118Hypoglycemic seizures (HP:0002173)1.83674962
119Deeply set eye (HP:0000490)1.82520209
120Lower limb muscle weakness (HP:0007340)1.82231836
121Amyotrophic lateral sclerosis (HP:0007354)1.81994743
122Apathy (HP:0000741)1.81641001
123Global brain atrophy (HP:0002283)1.81205493
124Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.81019695
125Degeneration of the lateral corticospinal tracts (HP:0002314)1.81019695
126Papilledema (HP:0001085)1.79629792
127Retinal dysplasia (HP:0007973)1.79417525
128Craniofacial dystonia (HP:0012179)1.79288804
129Clumsiness (HP:0002312)1.78881882
130Type II lissencephaly (HP:0007260)1.78694815
131Choreoathetosis (HP:0001266)1.77750305
132Hypoglycemic coma (HP:0001325)1.77633221
133Glioma (HP:0009733)1.77351440
134CNS hypomyelination (HP:0003429)1.75414166
135Sleep apnea (HP:0010535)1.67659165
136Tetraplegia (HP:0002445)1.67582319
137Ependymoma (HP:0002888)1.65734718
138Congenital, generalized hypertrichosis (HP:0004540)1.64327197

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA46.52142123
2NTRK34.87706387
3RIPK44.51329162
4FRK3.84207966
5MAP3K92.98106588
6TRIM282.58730543
7MAP3K42.56403416
8MINK12.43565396
9KSR22.25860580
10CASK2.23577498
11MAP2K72.20543705
12ERBB32.16826522
13MAP3K122.14679769
14DAPK22.13643216
15BMPR22.09418829
16PNCK2.01487784
17NEK11.96238441
18KSR11.96061175
19WNK31.83562513
20PLK21.83520446
21NTRK11.81843775
22ARAF1.80031291
23DAPK11.79448208
24MAP2K41.77277609
25PRPF4B1.77266378
26MAP4K21.73984005
27MUSK1.67290454
28MAP3K131.65995740
29NUAK11.61172281
30PAK61.60346038
31GRK11.59285553
32MKNK21.56510722
33ACVR1B1.54641086
34MST41.53292311
35PTK2B1.53006909
36SIK21.52266494
37CAMKK11.51740145
38FES1.46731702
39BMPR1B1.45702744
40MARK11.44952734
41CDK51.40438733
42CAMKK21.38043921
43FGFR21.32941432
44GRK51.32606346
45TNIK1.31879973
46RAF11.27026628
47CAMK2B1.25941915
48CAMK2A1.22649551
49PRKCG1.21921381
50PRKD31.19551170
51NTRK21.16982915
52NME11.16174074
53PLK31.11742786
54MAP3K21.11703491
55CCNB11.11006159
56FGR1.02283560
57CDK190.92880772
58INSRR0.91184197
59STK380.91141338
60CSNK1G30.89974440
61EIF2AK30.88140017
62MAPK130.86900842
63CSNK1A1L0.86383691
64CSNK1G10.82933304
65SGK10.74589224
66CAMK10.72173899
67CDK180.70881123
68WNK40.70438051
69TYRO30.69182626
70CDK140.68685290
71ADRBK20.68415747
72SGK2230.67476143
73SGK4940.67476143
74CDK150.66456262
75LIMK10.66225835
76CAMK2D0.65950865
77VRK20.65855136
78OXSR10.65574606
79TAOK30.65477225
80STK110.64417084
81PINK10.64402146
82TNK20.64171874
83FER0.64134172
84TAF10.63834500
85PDPK10.62454275
86MAP3K10.62144191
87SGK20.61785869
88PRKCE0.58134415
89DYRK1A0.58087818
90CDK11A0.56772681
91STK38L0.56081308
92MAPKAPK50.54383458
93MAP2K10.53324157
94PDK10.53240743
95CAMK2G0.52821051
96GRK60.52626115
97EIF2AK10.52500155
98MKNK10.52139124
99UHMK10.51548430
100RET0.50234179
101AKT30.49330049
102BRAF0.49229830
103GRK70.48607679
104SIK30.48460705
105DMPK0.46827311
106PRKCQ0.46575018
107PAK30.46380000
108PRKCI0.45718592
109TAOK10.44939864
110ROCK20.44665354
111PRKCZ0.44062117
112PRKD20.43819027
113PIK3CA0.41992713
114MAPK100.41762737
115BCR0.41223099
116MOS0.40240455
117PKN10.40019847
118LATS20.39849198
119FYN0.39435808
120SGK30.38884050
121MARK20.38096108
122ALK0.37078474
123MAP3K70.36344102
124PRKCH0.36136827
125EIF2AK20.36135259
126ROCK10.35710250
127ZAK0.34799760
128TXK0.34529576
129* RPS6KA30.33649764
130NEK60.33495366
131CSNK1A10.33193597
132PRKACA0.32263832
133TAOK20.32169021
134MAP3K60.31630659
135STK390.31310889
136CSNK1G20.30260975
137MAPK120.29657846
138PRKCA0.28514725
139PHKG20.28188134
140PHKG10.28188134
141DAPK30.27559329

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.12570337
2* Long-term potentiation_Homo sapiens_hsa047203.26772567
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.92884464
4Circadian entrainment_Homo sapiens_hsa047132.83631866
5Olfactory transduction_Homo sapiens_hsa047402.78103933
6* Glutamatergic synapse_Homo sapiens_hsa047242.75843403
7* Amphetamine addiction_Homo sapiens_hsa050312.73034774
8Morphine addiction_Homo sapiens_hsa050322.60963823
9Synaptic vesicle cycle_Homo sapiens_hsa047212.53543826
10GABAergic synapse_Homo sapiens_hsa047272.51177898
11Salivary secretion_Homo sapiens_hsa049702.48362594
12* Dopaminergic synapse_Homo sapiens_hsa047282.22651084
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.15281231
14Taste transduction_Homo sapiens_hsa047422.06496506
15Vitamin B6 metabolism_Homo sapiens_hsa007502.03313258
16Long-term depression_Homo sapiens_hsa047301.99390812
17Gastric acid secretion_Homo sapiens_hsa049711.98505861
18* Renin secretion_Homo sapiens_hsa049241.92597305
19Serotonergic synapse_Homo sapiens_hsa047261.88553914
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.86298077
21* Calcium signaling pathway_Homo sapiens_hsa040201.86090952
22Cholinergic synapse_Homo sapiens_hsa047251.81529786
23Insulin secretion_Homo sapiens_hsa049111.81134037
24* Oxytocin signaling pathway_Homo sapiens_hsa049211.79337168
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60994411
26GnRH signaling pathway_Homo sapiens_hsa049121.59465897
27Cocaine addiction_Homo sapiens_hsa050301.55596150
28Collecting duct acid secretion_Homo sapiens_hsa049661.54921278
29Gap junction_Homo sapiens_hsa045401.41135682
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40231826
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.37412945
32cAMP signaling pathway_Homo sapiens_hsa040241.36963016
33Phosphatidylinositol signaling system_Homo sapiens_hsa040701.29827460
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.22248976
35Glioma_Homo sapiens_hsa052141.19434084
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.17358577
37Ether lipid metabolism_Homo sapiens_hsa005651.12165430
38* cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11721800
39Melanogenesis_Homo sapiens_hsa049161.11460224
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.11458188
41Protein export_Homo sapiens_hsa030601.10475752
42Estrogen signaling pathway_Homo sapiens_hsa049151.10208214
43Vascular smooth muscle contraction_Homo sapiens_hsa042701.09060201
44Pancreatic secretion_Homo sapiens_hsa049721.07347418
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05952391
46Cardiac muscle contraction_Homo sapiens_hsa042601.05555881
47Phototransduction_Homo sapiens_hsa047441.05544679
48Nitrogen metabolism_Homo sapiens_hsa009101.03625793
49Propanoate metabolism_Homo sapiens_hsa006401.03097051
50* Axon guidance_Homo sapiens_hsa043601.02233355
51* Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.95934718
52ErbB signaling pathway_Homo sapiens_hsa040120.93815474
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.92424736
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91995409
55Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89442358
56Choline metabolism in cancer_Homo sapiens_hsa052310.88643134
57Vibrio cholerae infection_Homo sapiens_hsa051100.88474665
58Butanoate metabolism_Homo sapiens_hsa006500.88129905
59Fatty acid biosynthesis_Homo sapiens_hsa000610.87863299
60Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.87849661
61Type II diabetes mellitus_Homo sapiens_hsa049300.87425070
62African trypanosomiasis_Homo sapiens_hsa051430.87328202
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.82707809
64Alzheimers disease_Homo sapiens_hsa050100.81585745
65Thyroid hormone synthesis_Homo sapiens_hsa049180.78904630
66* Oocyte meiosis_Homo sapiens_hsa041140.78339336
67RNA degradation_Homo sapiens_hsa030180.74249359
68Dorso-ventral axis formation_Homo sapiens_hsa043200.72420239
69* VEGF signaling pathway_Homo sapiens_hsa043700.71534749
70Regulation of autophagy_Homo sapiens_hsa041400.68808573
71Sulfur metabolism_Homo sapiens_hsa009200.66236667
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65993254
73Dilated cardiomyopathy_Homo sapiens_hsa054140.65853186
74* MAPK signaling pathway_Homo sapiens_hsa040100.63849377
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62868397
76Rap1 signaling pathway_Homo sapiens_hsa040150.62843466
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61610867
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59681707
79Ras signaling pathway_Homo sapiens_hsa040140.59056120
80beta-Alanine metabolism_Homo sapiens_hsa004100.57010724
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56082896
82* Glucagon signaling pathway_Homo sapiens_hsa049220.54950741
83Oxidative phosphorylation_Homo sapiens_hsa001900.54818132
84Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53998263
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.53457902
86Caffeine metabolism_Homo sapiens_hsa002320.53100010
87Tryptophan metabolism_Homo sapiens_hsa003800.52984901
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.51656147
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51104798
90Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51062702
91Inositol phosphate metabolism_Homo sapiens_hsa005620.50753090
92Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.50584614
93Non-small cell lung cancer_Homo sapiens_hsa052230.49685618
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49609204
95Fatty acid elongation_Homo sapiens_hsa000620.47865144
96RNA polymerase_Homo sapiens_hsa030200.45200326
97Linoleic acid metabolism_Homo sapiens_hsa005910.44043821
98Fatty acid metabolism_Homo sapiens_hsa012120.43860244
99alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43711167
100Prion diseases_Homo sapiens_hsa050200.42915005
101Peroxisome_Homo sapiens_hsa041460.41957719
102Alcoholism_Homo sapiens_hsa050340.39475413
103Tight junction_Homo sapiens_hsa045300.39425389
104Non-homologous end-joining_Homo sapiens_hsa034500.38833728
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38589575
106mTOR signaling pathway_Homo sapiens_hsa041500.38367420
107Histidine metabolism_Homo sapiens_hsa003400.38352536
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38345720
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38233640
110Selenocompound metabolism_Homo sapiens_hsa004500.37639548
111Ovarian steroidogenesis_Homo sapiens_hsa049130.37590653
112Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36244420
113Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35791765
114Arginine and proline metabolism_Homo sapiens_hsa003300.35604812
115Bile secretion_Homo sapiens_hsa049760.35127580
116Basal transcription factors_Homo sapiens_hsa030220.34166691
117Circadian rhythm_Homo sapiens_hsa047100.33694382
118* Wnt signaling pathway_Homo sapiens_hsa043100.33169198
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32541367
120Parkinsons disease_Homo sapiens_hsa050120.32292948
121Chemokine signaling pathway_Homo sapiens_hsa040620.31257721
122Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30649853
123* Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30483899
124Endocytosis_Homo sapiens_hsa041440.28723508
125Steroid biosynthesis_Homo sapiens_hsa001000.28716481
126Mineral absorption_Homo sapiens_hsa049780.27751359
127Type I diabetes mellitus_Homo sapiens_hsa049400.27338378
128Renal cell carcinoma_Homo sapiens_hsa052110.26392058
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.26391448
130Insulin signaling pathway_Homo sapiens_hsa049100.25540851
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.25402555
132Platelet activation_Homo sapiens_hsa046110.25274685
133Huntingtons disease_Homo sapiens_hsa050160.23476354
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.22187964
135Rheumatoid arthritis_Homo sapiens_hsa053230.21709321
136Salmonella infection_Homo sapiens_hsa051320.20596350

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