PPP4C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.55576053
2DNA deamination (GO:0045006)4.50740629
3DNA strand elongation involved in DNA replication (GO:0006271)4.34085853
4telomere maintenance via semi-conservative replication (GO:0032201)4.13490222
5DNA strand elongation (GO:0022616)4.12209262
6viral transcription (GO:0019083)4.08742516
7maturation of SSU-rRNA (GO:0030490)3.98910399
8DNA replication initiation (GO:0006270)3.98628186
9protein maturation by protein folding (GO:0022417)3.98162244
10translational termination (GO:0006415)3.98132400
11COPI coating of Golgi vesicle (GO:0048205)3.94002822
12Golgi transport vesicle coating (GO:0048200)3.94002822
13formation of translation preinitiation complex (GO:0001731)3.89896453
14DNA unwinding involved in DNA replication (GO:0006268)3.72135498
15telomere maintenance via recombination (GO:0000722)3.68471681
16ribosomal small subunit biogenesis (GO:0042274)3.68325911
17DNA replication checkpoint (GO:0000076)3.66121758
18translational elongation (GO:0006414)3.64254935
19ribosomal large subunit biogenesis (GO:0042273)3.60325674
20protein localization to kinetochore (GO:0034501)3.56960267
21negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.56826244
22translational initiation (GO:0006413)3.56325207
23pentose-phosphate shunt (GO:0006098)3.53371126
24nucleobase biosynthetic process (GO:0046112)3.47986923
25mitotic recombination (GO:0006312)3.43834893
26SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.40823462
27nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.40166011
28ribonucleoprotein complex biogenesis (GO:0022613)3.39946439
29mitotic metaphase plate congression (GO:0007080)3.33688906
30folic acid-containing compound biosynthetic process (GO:0009396)3.30812907
31ribosome assembly (GO:0042255)3.29712604
32mitotic nuclear envelope disassembly (GO:0007077)3.29575843
33protein targeting to ER (GO:0045047)3.28913823
34cotranslational protein targeting to membrane (GO:0006613)3.28380367
35ribosome biogenesis (GO:0042254)3.27212943
36telomere maintenance via telomere lengthening (GO:0010833)3.26932123
37purine nucleobase biosynthetic process (GO:0009113)3.23734958
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.23687774
39GDP-mannose metabolic process (GO:0019673)3.20658135
40protein localization to chromosome, centromeric region (GO:0071459)3.19704378
41NADPH regeneration (GO:0006740)3.18555591
42pinocytosis (GO:0006907)3.17943242
43viral life cycle (GO:0019058)3.17671546
44DNA replication-dependent nucleosome assembly (GO:0006335)3.15440740
45DNA replication-dependent nucleosome organization (GO:0034723)3.15440740
46response to peptidoglycan (GO:0032494)3.14263810
47CENP-A containing nucleosome assembly (GO:0034080)3.09988940
48establishment of protein localization to endoplasmic reticulum (GO:0072599)3.09853774
49regulation of mammary gland epithelial cell proliferation (GO:0033599)3.09832237
50peptidyl-arginine omega-N-methylation (GO:0035247)3.09097383
51chromatin remodeling at centromere (GO:0031055)3.09009887
52protein localization to endoplasmic reticulum (GO:0070972)3.07929565
53IMP biosynthetic process (GO:0006188)3.07386955
54cellular protein complex disassembly (GO:0043624)3.07357328
55nucleotide-excision repair, DNA gap filling (GO:0006297)3.06468803
56rRNA processing (GO:0006364)3.02448668
57nuclear envelope disassembly (GO:0051081)3.02444048
58membrane disassembly (GO:0030397)3.02444048
59proline biosynthetic process (GO:0006561)3.02314307
60regulation of superoxide anion generation (GO:0032928)3.01826724
61spliceosomal snRNP assembly (GO:0000387)2.97925614
62rRNA metabolic process (GO:0016072)2.92585968
63DNA replication-independent nucleosome organization (GO:0034724)2.91507702
64DNA replication-independent nucleosome assembly (GO:0006336)2.91507702
65nuclear envelope reassembly (GO:0031468)2.88916756
66mitotic nuclear envelope reassembly (GO:0007084)2.88916756
67glucose catabolic process (GO:0006007)2.87949169
68negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.85954282
69positive regulation by symbiont of host defense response (GO:0052509)2.85804556
70modulation by symbiont of host defense response (GO:0052031)2.85804556
71modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.85804556
72modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.85804556
73positive regulation by organism of defense response of other organism involved in symbiotic interact2.85804556
74modulation by symbiont of host immune response (GO:0052553)2.85804556
75anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.85007878
76pentose metabolic process (GO:0019321)2.83717470
77protein complex disassembly (GO:0043241)2.81194255
78negative regulation of myeloid cell apoptotic process (GO:0033033)2.81180167
79metaphase plate congression (GO:0051310)2.80846193
80proteasome assembly (GO:0043248)2.80413838
81regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.80180622
82nuclear-transcribed mRNA catabolic process (GO:0000956)2.78884625
83negative regulation of erythrocyte differentiation (GO:0045647)2.76964336
84translation (GO:0006412)2.75743645
85pseudouridine synthesis (GO:0001522)2.75572527
86nuclear pore organization (GO:0006999)2.75004654
87transcription-coupled nucleotide-excision repair (GO:0006283)2.74032154
88positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.73401664
89deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.72930404
90regulation of spindle organization (GO:0090224)2.71864314
91antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.71813476
92establishment of chromosome localization (GO:0051303)2.68649325
93IMP metabolic process (GO:0046040)2.68635958
94antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.66835223
95mRNA catabolic process (GO:0006402)2.66221017
96RNA catabolic process (GO:0006401)2.66136264
97modulation by virus of host process (GO:0019054)2.64685688
98macromolecular complex disassembly (GO:0032984)2.64222798
99rRNA modification (GO:0000154)2.63025487
100folic acid metabolic process (GO:0046655)2.62954321
101modulation by symbiont of host cellular process (GO:0044068)2.62512485
102regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.62374426
103positive regulation of Cdc42 GTPase activity (GO:0043089)2.61983308
104Arp2/3 complex-mediated actin nucleation (GO:0034314)2.61854526
105negative regulation of ligase activity (GO:0051352)2.61790968
106negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.61790968
107pyrimidine nucleoside salvage (GO:0043097)2.61492661
108pyrimidine-containing compound salvage (GO:0008655)2.61492661
109G1/S transition of mitotic cell cycle (GO:0000082)2.59943583
110cell cycle G1/S phase transition (GO:0044843)2.59943583
111kinetochore organization (GO:0051383)2.59744292
112UV protection (GO:0009650)2.59473178
113negative regulation of B cell apoptotic process (GO:0002903)2.58818899
114negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.57950597
115negative regulation of RNA splicing (GO:0033119)2.57734368
116DNA duplex unwinding (GO:0032508)2.57555752
117nucleobase-containing small molecule interconversion (GO:0015949)2.57527389
118mitotic sister chromatid segregation (GO:0000070)2.56022564
119DNA geometric change (GO:0032392)2.55917241
120* NIK/NF-kappaB signaling (GO:0038061)2.55023945
121mitotic chromosome condensation (GO:0007076)2.54574741
122viral mRNA export from host cell nucleus (GO:0046784)2.54224429
123telomere maintenance (GO:0000723)2.53787332
124telomere organization (GO:0032200)2.53599712
125neutrophil activation involved in immune response (GO:0002283)2.53013813
126immunoglobulin mediated immune response (GO:0016064)2.52711410
127regulation of nuclear cell cycle DNA replication (GO:0033262)2.52645546
128histone arginine methylation (GO:0034969)2.51494652
129nuclear pore complex assembly (GO:0051292)2.51288007
130negative regulation of interleukin-12 production (GO:0032695)2.51061463
131RNA splicing, via transesterification reactions (GO:0000375)2.50703098
132mRNA splicing, via spliceosome (GO:0000398)2.50358259
133RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.50358259
134attachment of spindle microtubules to kinetochore (GO:0008608)2.50136474
135somatic diversification of immune receptors via somatic mutation (GO:0002566)2.49741518
136somatic hypermutation of immunoglobulin genes (GO:0016446)2.49741518
137histone exchange (GO:0043486)2.49649296
138negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.49290325
139DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.48187251
140respiratory burst (GO:0045730)2.47752475
141establishment of viral latency (GO:0019043)2.47155013
142negative regulation of chromosome segregation (GO:0051985)2.46698746
143chromatin assembly or disassembly (GO:0006333)2.46339437
144apoptotic process involved in morphogenesis (GO:0060561)2.45929687
145protein localization to endosome (GO:0036010)2.45878432
146signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.45631744
147protein retention in ER lumen (GO:0006621)2.42848322
148retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.42038291
149T cell apoptotic process (GO:0070231)2.41309426
1503-UTR-mediated mRNA stabilization (GO:0070935)2.40941615
151pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.39936039
152positive regulation of gamma-delta T cell activation (GO:0046645)2.39860096
153regulation of translational termination (GO:0006449)2.38804734
154regulation of defense response to virus by virus (GO:0050690)2.37308539
155epithelial cell differentiation involved in prostate gland development (GO:0060742)2.36516818
156positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.36213429
157peptidyl-arginine methylation (GO:0018216)2.34644318
158peptidyl-arginine N-methylation (GO:0035246)2.34644318
159glucose 6-phosphate metabolic process (GO:0051156)2.34315446
160spliceosomal tri-snRNP complex assembly (GO:0000244)2.34131572
161antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.34052473
162lipopolysaccharide-mediated signaling pathway (GO:0031663)2.32348781
163positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.30572490
164maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.30097080
165antigen processing and presentation of endogenous antigen (GO:0019883)2.28826069
166purine deoxyribonucleotide catabolic process (GO:0009155)2.28138994
167cellular response to interleukin-4 (GO:0071353)2.27862576
168pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.27337387
169positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.26925321
170barbed-end actin filament capping (GO:0051016)2.26896640
171virion assembly (GO:0019068)2.23982995
172negative regulation of cell killing (GO:0031342)2.23800435
173negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.23800435
174detection of bacterium (GO:0016045)2.23728515
175negative regulation of cell size (GO:0045792)2.23547103
176regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.22174377
177deoxyribonucleotide catabolic process (GO:0009264)2.21798625
178establishment of integrated proviral latency (GO:0075713)2.20799183
179deoxyribose phosphate biosynthetic process (GO:0046385)2.20783914
1802-deoxyribonucleotide biosynthetic process (GO:0009265)2.20783914
181negative regulation of DNA-templated transcription, elongation (GO:0032785)2.20679477
182deoxyribose phosphate catabolic process (GO:0046386)2.18723793
183antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.17918750
184nucleotide salvage (GO:0043173)2.16948231
185detection of other organism (GO:0098543)2.16880186
186guanosine-containing compound biosynthetic process (GO:1901070)2.16393755
187regulation of type I interferon-mediated signaling pathway (GO:0060338)2.15528269
188maternal placenta development (GO:0001893)2.15017375
189amyloid precursor protein catabolic process (GO:0042987)2.14613626

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.24510241
2MYC_18555785_ChIP-Seq_MESCs_Mouse3.80642398
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.61387092
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.39519734
5E2F4_17652178_ChIP-ChIP_JURKAT_Human2.98594726
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.74049685
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.70374674
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.56001810
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.51575487
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.50506874
11* GABP_17652178_ChIP-ChIP_JURKAT_Human2.47049761
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.46638080
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.44728212
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.42700895
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.25585656
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.18654771
17XRN2_22483619_ChIP-Seq_HELA_Human2.17595334
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.12473523
19MYC_22102868_ChIP-Seq_BL_Human2.08228726
20VDR_23849224_ChIP-Seq_CD4+_Human2.05465506
21ELK3_25401928_ChIP-Seq_HUVEC_Human2.02810572
22* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.01899872
23ELF1_17652178_ChIP-ChIP_JURKAT_Human1.98974791
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.96504850
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.95849163
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.94418411
27LXR_22292898_ChIP-Seq_THP-1_Human1.93883717
28PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.89866833
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84452928
30E2F1_18555785_ChIP-Seq_MESCs_Mouse1.80340824
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.79686447
32BP1_19119308_ChIP-ChIP_Hs578T_Human1.79298689
33DCP1A_22483619_ChIP-Seq_HELA_Human1.77980022
34FOXP3_21729870_ChIP-Seq_TREG_Human1.77078801
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.72938148
36* GABP_19822575_ChIP-Seq_HepG2_Human1.72821748
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.67545349
38NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65571459
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.64412562
40TP63_17297297_ChIP-ChIP_HaCaT_Human1.62338756
41CIITA_25753668_ChIP-Seq_RAJI_Human1.61405439
42* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.60170655
43* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59319121
44RACK7_27058665_Chip-Seq_MCF-7_Human1.59199054
45TTF2_22483619_ChIP-Seq_HELA_Human1.58519720
46VDR_21846776_ChIP-Seq_THP-1_Human1.57468454
47AR_21909140_ChIP-Seq_LNCAP_Human1.57410164
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.56565454
49ZNF263_19887448_ChIP-Seq_K562_Human1.56281738
50KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.55954740
51RARG_19884340_ChIP-ChIP_MEFs_Mouse1.54193637
52POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.53436108
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48453491
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.47801031
55THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.44844651
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41925068
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41592850
58* VDR_24763502_ChIP-Seq_THP-1_Human1.40967815
59TET1_21451524_ChIP-Seq_MESCs_Mouse1.40303752
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39973126
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.39781897
62YY1_21170310_ChIP-Seq_MESCs_Mouse1.39316775
63THAP11_20581084_ChIP-Seq_MESCs_Mouse1.38470234
64HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.37776099
65FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37343813
66KDM5A_27292631_Chip-Seq_BREAST_Human1.35701958
67STAT3_1855785_ChIP-Seq_MESCs_Mouse1.34563587
68TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33653528
69* SPI1_23547873_ChIP-Seq_NB4_Human1.33507518
70ELK1_19687146_ChIP-ChIP_HELA_Human1.32999966
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.32378981
72* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.31855010
73TCF7_22412390_ChIP-Seq_EML_Mouse1.30266223
74CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29938251
75IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.27291209
76P68_20966046_ChIP-Seq_HELA_Human1.26790739
77KDM2B_26808549_Chip-Seq_DND41_Human1.26264924
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26061107
79ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.25734786
80ELF1_20517297_ChIP-Seq_JURKAT_Human1.24261072
81SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23967649
82NOTCH1_21737748_ChIP-Seq_TLL_Human1.22962341
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.21284259
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20475416
85TFEB_21752829_ChIP-Seq_HELA_Human1.19497274
86TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18728756
87KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18057471
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.16976567
89GATA1_22383799_ChIP-Seq_G1ME_Mouse1.16424909
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.15369466
91CTCF_27219007_Chip-Seq_ERYTHROID_Human1.14438908
92SRF_21415370_ChIP-Seq_HL-1_Mouse1.14348356
93YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13960001
94IRF8_21731497_ChIP-ChIP_J774_Mouse1.13950584
95MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.12802961
96PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12325625
97NCOR1_26117541_ChIP-Seq_K562_Human1.12271066
98TP63_19390658_ChIP-ChIP_HaCaT_Human1.10921784
99E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.10057377
100* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09712694
101* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09387360
102BCL6_27268052_Chip-Seq_Bcells_Human1.09325990
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.09275357
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08980431
105BCOR_27268052_Chip-Seq_Bcells_Human1.07883107
106NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.07685343
107CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.06704474
108MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06428494
109IRF8_22096565_ChIP-ChIP_GC-B_Human1.05821389
110E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.05770201
111MAF_26560356_Chip-Seq_TH1_Human1.05336872
112KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.05120916
113ATF3_27146783_Chip-Seq_COLON_Human1.04469276
114GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03970419
115CTCF_26484167_Chip-Seq_Bcells_Mouse1.03714672
116CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03672517
117E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03666368
118UTX_26944678_Chip-Seq_JUKART_Human1.01183660
119MYB_21317192_ChIP-Seq_ERMYB_Mouse1.01135437
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00701416
121POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.99387332
122NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.98112693
123STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97931780
124* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97677216
125MYB_26560356_Chip-Seq_TH2_Human0.96625417
126MYB_26560356_Chip-Seq_TH1_Human0.96621261
127RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.96218976
128NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94858398
129RUNX1_22412390_ChIP-Seq_EML_Mouse0.94043101
130HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.93159748
131CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.92441893
132BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90974362
133MAF_26560356_Chip-Seq_TH2_Human0.89587673
134BRD4_27068464_Chip-Seq_AML-cells_Mouse0.88741481
135* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88292618
136SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85002826

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.66792703
2MP0003111_abnormal_nucleus_morphology3.58756640
3* MP0004957_abnormal_blastocyst_morpholog3.44083951
4MP0010094_abnormal_chromosome_stability3.40348940
5MP0005058_abnormal_lysosome_morphology3.39465181
6* MP0003077_abnormal_cell_cycle3.18746404
7MP0008057_abnormal_DNA_replication2.92733071
8MP0005451_abnormal_body_composition2.85642702
9MP0008058_abnormal_DNA_repair2.62296803
10MP0008007_abnormal_cellular_replicative2.51126754
11MP0008260_abnormal_autophagy2.44201488
12MP0002396_abnormal_hematopoietic_system2.38538717
13MP0010352_gastrointestinal_tract_polyps2.26897452
14MP0003191_abnormal_cellular_cholesterol2.11953760
15MP0000490_abnormal_crypts_of2.04690914
16MP0009333_abnormal_splenocyte_physiolog2.03633047
17MP0002877_abnormal_melanocyte_morpholog2.01143341
18MP0001835_abnormal_antigen_presentation1.96133241
19MP0008932_abnormal_embryonic_tissue1.95272890
20MP0003763_abnormal_thymus_physiology1.93782592
21MP0003172_abnormal_lysosome_physiology1.92251067
22MP0000350_abnormal_cell_proliferation1.82930079
23MP0001730_embryonic_growth_arrest1.77219589
24MP0000685_abnormal_immune_system1.72670274
25MP0003436_decreased_susceptibility_to1.70492416
26MP0001849_ear_inflammation1.70323571
27* MP0002398_abnormal_bone_marrow1.65759313
28MP0004808_abnormal_hematopoietic_stem1.64152108
29MP0003786_premature_aging1.60018443
30MP0010307_abnormal_tumor_latency1.58661034
31MP0001800_abnormal_humoral_immune1.56269146
32MP0003300_gastrointestinal_ulcer1.54981236
33MP0002254_reproductive_system_inflammat1.54795181
34MP0005397_hematopoietic_system_phenotyp1.52064015
35MP0001545_abnormal_hematopoietic_system1.52064015
36MP0002019_abnormal_tumor_incidence1.50990560
37MP0002722_abnormal_immune_system1.50899560
38MP0010234_abnormal_vibrissa_follicle1.50294583
39MP0005671_abnormal_response_to1.49757114
40MP0003123_paternal_imprinting1.49729012
41MP0000689_abnormal_spleen_morphology1.49042602
42MP0003453_abnormal_keratinocyte_physiol1.48004197
43MP0009785_altered_susceptibility_to1.46505814
44MP0004858_abnormal_nervous_system1.45948744
45MP0002796_impaired_skin_barrier1.45116167
46MP0002452_abnormal_antigen_presenting1.44966293
47MP0000858_altered_metastatic_potential1.44886538
48MP0004185_abnormal_adipocyte_glucose1.44326625
49MP0000703_abnormal_thymus_morphology1.40269940
50MP0005501_abnormal_skin_physiology1.39400321
51MP0001853_heart_inflammation1.38014313
52* MP0002420_abnormal_adaptive_immunity1.37648186
53* MP0001819_abnormal_immune_cell1.37176821
54MP0002405_respiratory_system_inflammati1.35625789
55* MP0000716_abnormal_immune_system1.33442368
56MP0005025_abnormal_response_to1.33428626
57MP0005000_abnormal_immune_tolerance1.33378493
58MP0000313_abnormal_cell_death1.33204646
59MP0002723_abnormal_immune_serum1.33008838
60* MP0002429_abnormal_blood_cell1.32842800
61MP0001672_abnormal_embryogenesis/_devel1.31839039
62MP0005380_embryogenesis_phenotype1.31839039
63MP0009278_abnormal_bone_marrow1.31192563
64MP0001697_abnormal_embryo_size1.29486502
65* MP0002080_prenatal_lethality1.24909606
66MP0010155_abnormal_intestine_physiology1.18436344
67MP0003984_embryonic_growth_retardation1.17468193
68MP0002088_abnormal_embryonic_growth/wei1.15669979
69MP0003075_altered_response_to1.15667413
70MP0000343_altered_response_to1.15063962
71MP0005076_abnormal_cell_differentiation1.13560227
72MP0003303_peritoneal_inflammation1.13463934
73MP0002086_abnormal_extraembryonic_tissu1.12087294
74MP0000678_abnormal_parathyroid_gland1.09417627
75MP0003718_maternal_effect1.08646830
76MP0005387_immune_system_phenotype1.08061324
77MP0001790_abnormal_immune_system1.08061324
78MP0002132_abnormal_respiratory_system1.08056755
79MP0002148_abnormal_hypersensitivity_rea1.06154402
80MP0003567_abnormal_fetal_cardiomyocyte1.05143550
81MP0002419_abnormal_innate_immunity1.04301006
82* MP0002085_abnormal_embryonic_tissue1.04242896
83MP0008877_abnormal_DNA_methylation1.03921299
84MP0002166_altered_tumor_susceptibility1.03344834
85MP0003448_altered_tumor_morphology1.03024795
86MP0002006_tumorigenesis1.01437238
87MP0004197_abnormal_fetal_growth/weight/0.99099749
88MP0003186_abnormal_redox_activity0.99090360
89MP0006054_spinal_hemorrhage0.98166340
90MP0000465_gastrointestinal_hemorrhage0.96827547
91MP0005023_abnormal_wound_healing0.96398697
92MP0004233_abnormal_muscle_weight0.95693981
93MP0001727_abnormal_embryo_implantation0.95340624
94MP0005075_abnormal_melanosome_morpholog0.94170122
95MP0005464_abnormal_platelet_physiology0.93647525
96MP0009840_abnormal_foam_cell0.93508010
97MP0004510_myositis0.93371503
98MP0003806_abnormal_nucleotide_metabolis0.93184724
99MP0002084_abnormal_developmental_patter0.92172566
100MP0001873_stomach_inflammation0.90958038
101MP0006035_abnormal_mitochondrial_morpho0.90894340
102MP0001845_abnormal_inflammatory_respons0.89090288
103MP0005174_abnormal_tail_pigmentation0.87815427
104MP0004947_skin_inflammation0.87513151
105MP0010030_abnormal_orbit_morphology0.86850994
106MP0003315_abnormal_perineum_morphology0.84457620
107MP0000477_abnormal_intestine_morphology0.83882763
108MP0009764_decreased_sensitivity_to0.83868905
109MP0003221_abnormal_cardiomyocyte_apopto0.82788155
110MP0003866_abnormal_defecation0.82093086
111MP0004264_abnormal_extraembryonic_tissu0.81271598
112MP0001216_abnormal_epidermal_layer0.80756644
113MP0002998_abnormal_bone_remodeling0.80385255
114MP0002210_abnormal_sex_determination0.78803156
115MP0002089_abnormal_postnatal_growth/wei0.77968684
116MP0009931_abnormal_skin_appearance0.77195155
117MP0005083_abnormal_biliary_tract0.76790290
118MP0005390_skeleton_phenotype0.76202585
119MP0003566_abnormal_cell_adhesion0.75067189
120MP0006082_CNS_inflammation0.74762991
121MP0001293_anophthalmia0.74742373
122MP0000604_amyloidosis0.74698381
123MP0001145_abnormal_male_reproductive0.72924474
124MP0003705_abnormal_hypodermis_morpholog0.71855931
125* MP0000358_abnormal_cell_content/0.71403728
126MP0003724_increased_susceptibility_to0.66881985
127MP0005621_abnormal_cell_physiology0.66781100
128MP0001533_abnormal_skeleton_physiology0.64772560
129* MP0005384_cellular_phenotype0.63776583
130MP0008469_abnormal_protein_level0.63533982
131MP0001119_abnormal_female_reproductive0.62935963
132MP0000371_diluted_coat_color0.62658901

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.30614253
2Reticulocytopenia (HP:0001896)4.24683717
3Abnormality of cells of the erythroid lineage (HP:0012130)4.24514039
4Abnormal number of erythroid precursors (HP:0012131)4.05071535
5Abnormality of macrophages (HP:0004311)3.47770710
6Breast hypoplasia (HP:0003187)3.35363257
7Oral leukoplakia (HP:0002745)3.10656394
8Vertebral compression fractures (HP:0002953)3.08785556
9Abnormality of glycolipid metabolism (HP:0010969)3.07392768
10Abnormality of liposaccharide metabolism (HP:0010968)3.07392768
11Abnormality of glycosphingolipid metabolism (HP:0004343)3.07392768
12Abnormal gallbladder physiology (HP:0012438)3.06279829
13Cholecystitis (HP:0001082)3.06279829
14Increased serum ferritin (HP:0003281)3.01432855
15Aplastic anemia (HP:0001915)3.00526139
16Selective tooth agenesis (HP:0001592)2.96302028
17Degeneration of anterior horn cells (HP:0002398)2.95261148
18Abnormality of the anterior horn cell (HP:0006802)2.95261148
19IgM deficiency (HP:0002850)2.88829376
20Ragged-red muscle fibers (HP:0003200)2.85071040
21Pallor (HP:0000980)2.83886613
22Thrombocytosis (HP:0001894)2.83823257
23Macrocytic anemia (HP:0001972)2.80150706
24Increased cerebral lipofuscin (HP:0011813)2.76969809
25Colon cancer (HP:0003003)2.76828759
26Chromosomal breakage induced by crosslinking agents (HP:0003221)2.74151858
27Patellar aplasia (HP:0006443)2.70846873
28Elevated erythrocyte sedimentation rate (HP:0003565)2.70427204
29Chromsome breakage (HP:0040012)2.70163167
30Trismus (HP:0000211)2.65355802
31Carpal bone hypoplasia (HP:0001498)2.64806114
32Hypertensive crisis (HP:0100735)2.64172761
33Hepatosplenomegaly (HP:0001433)2.62467859
34Absent thumb (HP:0009777)2.58454722
35Aplasia/Hypoplasia of the patella (HP:0006498)2.56818982
36Agnosia (HP:0010524)2.55801518
37Multiple enchondromatosis (HP:0005701)2.54248577
38Purpura (HP:0000979)2.54155747
39Rough bone trabeculation (HP:0100670)2.51152230
40Dysostosis multiplex (HP:0000943)2.49398478
41Vacuolated lymphocytes (HP:0001922)2.49314114
42Microretrognathia (HP:0000308)2.48362272
43Increased neuronal autofluorescent lipopigment (HP:0002074)2.46023231
44Recurrent abscess formation (HP:0002722)2.45439862
45Meckel diverticulum (HP:0002245)2.41586582
46Myelodysplasia (HP:0002863)2.37851462
47Increased IgM level (HP:0003496)2.34781154
48Progressive muscle weakness (HP:0003323)2.33844417
49Abnormality of T cell physiology (HP:0011840)2.32181503
50Abnormality of the ileum (HP:0001549)2.32092759
51Abnormality of the preputium (HP:0100587)2.29971038
52Neoplasm of the pancreas (HP:0002894)2.29194172
53Eczematoid dermatitis (HP:0000976)2.27736231
54Loss of speech (HP:0002371)2.27388515
55Medulloblastoma (HP:0002885)2.26518731
56Abnormality of T cells (HP:0002843)2.26282266
57Aplasia/Hypoplasia of the sacrum (HP:0008517)2.25334542
58Basal cell carcinoma (HP:0002671)2.24894940
59Myositis (HP:0100614)2.24479888
60Pustule (HP:0200039)2.24120079
61Achilles tendon contracture (HP:0001771)2.24083658
62Bone marrow hypocellularity (HP:0005528)2.21266172
6311 pairs of ribs (HP:0000878)2.20896356
64Lymphoma (HP:0002665)2.17931055
65Petechiae (HP:0000967)2.16344167
66Abnormality of chromosome stability (HP:0003220)2.16193989
67J-shaped sella turcica (HP:0002680)2.15576537
68Aplasia/Hypoplasia of the uvula (HP:0010293)2.13051278
69Premature graying of hair (HP:0002216)2.12228297
70Distal lower limb muscle weakness (HP:0009053)2.11501187
71Recurrent viral infections (HP:0004429)2.10247320
72Abnormality of iron homeostasis (HP:0011031)2.10032981
73Broad distal phalanx of finger (HP:0009836)2.09728339
74Ependymoma (HP:0002888)2.08809280
75Cellular immunodeficiency (HP:0005374)2.08719372
76Increased IgE level (HP:0003212)2.06428674
77Microvesicular hepatic steatosis (HP:0001414)2.05196093
78Cleft eyelid (HP:0000625)2.04497777
79Tracheoesophageal fistula (HP:0002575)2.04490023
80Type I transferrin isoform profile (HP:0003642)2.03344673
81Abnormality of the Achilles tendon (HP:0005109)2.01932690
82Recurrent fungal infections (HP:0002841)2.01754525
83Amaurosis fugax (HP:0100576)2.01160803
84Distal lower limb amyotrophy (HP:0008944)1.98570055
85Hyperacusis (HP:0010780)1.97704437
86Premature ovarian failure (HP:0008209)1.97265361
87Chronic otitis media (HP:0000389)1.97264364
88Long palpebral fissure (HP:0000637)1.96778312
89Recurrent bronchitis (HP:0002837)1.94610426
90Recurrent bacterial skin infections (HP:0005406)1.94400216
91Impulsivity (HP:0100710)1.93746694
92Absent radius (HP:0003974)1.93630052
93Centrally nucleated skeletal muscle fibers (HP:0003687)1.93581309
94IgG deficiency (HP:0004315)1.93364771
95Abnormality of polysaccharide metabolism (HP:0011012)1.93349816
96Abnormality of glycosaminoglycan metabolism (HP:0004371)1.93349816
97Abnormality of mucopolysaccharide metabolism (HP:0011020)1.93349816
98Slender long bone (HP:0003100)1.93227986
99Systemic lupus erythematosus (HP:0002725)1.92817990
100Meningitis (HP:0001287)1.91112696
101Progressive neurologic deterioration (HP:0002344)1.90905849
102Prolonged neonatal jaundice (HP:0006579)1.90292893
103Recurrent gram-negative bacterial infections (HP:0005420)1.89207710
104Mediastinal lymphadenopathy (HP:0100721)1.88986917
105Small intestinal stenosis (HP:0012848)1.88488265
106Duodenal stenosis (HP:0100867)1.88488265
107Combined immunodeficiency (HP:0005387)1.88357990
108Urticaria (HP:0001025)1.87299076
109Testicular atrophy (HP:0000029)1.86906095
110Abnormality of the umbilical cord (HP:0010881)1.86288680
111T lymphocytopenia (HP:0005403)1.85206110
112Abnormality of the distal phalanges of the toes (HP:0010182)1.85058615
113Premature rupture of membranes (HP:0001788)1.84854068
114Cerebral hypomyelination (HP:0006808)1.83704684
115Gastrointestinal inflammation (HP:0004386)1.83362515
116Biconcave vertebral bodies (HP:0004586)1.82398819
117Poor head control (HP:0002421)1.82102823
118Panhypogammaglobulinemia (HP:0003139)1.82028316
119Poikiloderma (HP:0001029)1.81191379
120Mucopolysacchariduria (HP:0008155)1.81140333
121Urinary glycosaminoglycan excretion (HP:0003541)1.81140333
122Abnormal trabecular bone morphology (HP:0100671)1.80251823
123Squamous cell carcinoma (HP:0002860)1.78832385
124Upper motor neuron abnormality (HP:0002127)1.78700184
125Axonal loss (HP:0003447)1.78310203
126Pancytopenia (HP:0001876)1.78260935
127Orchitis (HP:0100796)1.78026460
128Granulocytopenia (HP:0001913)1.77853744
129Seborrheic dermatitis (HP:0001051)1.77068595
130Abnormality of T cell number (HP:0011839)1.76955690
131Abnormality of cells of the lymphoid lineage (HP:0012140)1.76214425
132Cervical subluxation (HP:0003308)1.75185416
133Atresia of the external auditory canal (HP:0000413)1.75080150
134Absent forearm bone (HP:0003953)1.74043330
135Aplasia involving forearm bones (HP:0009822)1.74043330
136Gastrointestinal dysmotility (HP:0002579)1.73388467
137Abnormal number of incisors (HP:0011064)1.73302881
138Hemorrhage of the eye (HP:0011885)1.73109096
139Reduced antithrombin III activity (HP:0001976)1.72838513
140Fasciculations (HP:0002380)1.72804523
141Muscle fiber atrophy (HP:0100295)1.72539557
142Chronic obstructive pulmonary disease (HP:0006510)1.72438501
143Obstructive lung disease (HP:0006536)1.72438501
144Polygenic inheritance (HP:0010982)1.72168918
145Leukopenia (HP:0001882)1.72118031
146Hypertriglyceridemia (HP:0002155)1.70822646
147Nonimmune hydrops fetalis (HP:0001790)1.70352508
148Pulmonary fibrosis (HP:0002206)1.70069926
149Abnormal delayed hypersensitivity skin test (HP:0002963)1.69961622
150Nasal polyposis (HP:0100582)1.69719844
151Triphalangeal thumb (HP:0001199)1.69289126
152Atrophy/Degeneration involving motor neurons (HP:0007373)1.69145556
153Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.68950582
154Prominent nose (HP:0000448)1.68864917
155Secondary amenorrhea (HP:0000869)1.68701625
156Overlapping toe (HP:0001845)1.67926854
157Abnormality of pyrimidine metabolism (HP:0004353)1.67918765
158Reticulocytosis (HP:0001923)1.67364977
159Deep venous thrombosis (HP:0002625)1.66933346
160Orthostatic hypotension (HP:0001278)1.65942410
161Cholelithiasis (HP:0001081)1.65760022
162Cellulitis (HP:0100658)1.65534294
163Sloping forehead (HP:0000340)1.65481241
164Progressive external ophthalmoplegia (HP:0000590)1.64671296
165Increased connective tissue (HP:0009025)1.60462713
166Recurrent skin infections (HP:0001581)1.59355018
167Gingivitis (HP:0000230)1.59118289
168Micronodular cirrhosis (HP:0001413)1.58783422
169Hyperparathyroidism (HP:0000843)1.58347216
170Abnormal umbilical cord blood vessels (HP:0011403)1.57847039
171Single umbilical artery (HP:0001195)1.57847039
172Abnormality of the fetal cardiovascular system (HP:0010948)1.57847039
173Premature skin wrinkling (HP:0100678)1.57679324
174Agammaglobulinemia (HP:0004432)1.57069432
175Hypergammaglobulinemia (HP:0010702)1.56417684
176Growth hormone excess (HP:0000845)1.56066667
177Thoracic kyphosis (HP:0002942)1.55130413
178Broad face (HP:0000283)1.55046278
179Colitis (HP:0002583)1.54910264

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.19672367
2WEE13.30427997
3SMG13.09873854
4NME22.87300696
5CDC72.65700952
6VRK22.64994015
7EIF2AK12.47056619
8NEK22.41018965
9TESK22.33683330
10MAP4K12.28584583
11RPS6KA41.98943922
12EIF2AK31.90289714
13MAP3K101.84834957
14PRPF4B1.79960852
15SIK11.78046190
16TLK11.77878368
17STK161.76611600
18TAOK21.72097572
19SRPK11.71314434
20PLK41.68274669
21EEF2K1.68186950
22ARAF1.64915069
23STK101.64427893
24EPHA21.63838891
25ACVR1B1.63059578
26DYRK31.62116571
27TTK1.61732343
28RPS6KB21.58933787
29BCKDK1.57252459
30KDR1.55981025
31CDK71.53632918
32BLK1.53310442
33PASK1.49200486
34PLK11.46919985
35PIM21.43776443
36BRSK21.43243089
37TSSK61.42791009
38VRK11.38275174
39MAP3K81.33676595
40PAK41.33358380
41CDK41.31754975
42TAOK11.30705089
43TYK21.28854013
44AURKB1.28659514
45ATR1.28111738
46RIPK41.26929855
47ICK1.25754098
48SCYL21.24337409
49PIM11.20825962
50IRAK41.20485793
51TESK11.18971422
52FLT31.18963452
53ZAP701.15051316
54JAK31.11848642
55LRRK21.09187731
56STK41.08383583
57SIK31.06759511
58MAP2K31.05654335
59CDK121.03791981
60MAP3K111.01528196
61BTK1.00975655
62MKNK11.00296648
63CHEK20.97079271
64AURKA0.95120897
65GRK60.94864206
66NEK10.94568019
67ZAK0.92834659
68LIMK10.92784153
69TXK0.92617005
70IRAK30.92150561
71TGFBR10.91409390
72PTK60.90805574
73PKN20.90221416
74FGFR40.89261747
75KIT0.87101750
76MAPKAPK30.85476568
77TBK10.83978661
78IKBKB0.83773869
79MAP3K130.83501637
80MAP3K10.83153665
81TEC0.82859258
82CHEK10.81449385
83ABL20.79381836
84CSF1R0.77516832
85TRIB30.77201836
86ERN10.74133258
87BRSK10.71796136
88MKNK20.71225548
89PLK30.70627658
90RIPK10.69853940
91EPHB10.69230582
92MAP3K30.69073139
93IRAK20.65962153
94PAK10.65239715
95MAP2K20.65225130
96PRKD20.62335004
97EIF2AK20.61234383
98KSR20.59259617
99TTN0.58743788
100IKBKE0.58513406
101FGR0.57699310
102PBK0.57657917
103CHUK0.57352428
104NLK0.57041013
105RPS6KA50.55780315
106DAPK10.54755392
107CDK20.54314601
108PDPK10.54246883
109CDK60.53993920
110MATK0.52459263
111MST40.52362389
112CLK10.51632751
113CSNK2A10.51113072
114BRAF0.50883132
115MARK30.50654651
116CDK80.50012707
117FES0.49440909
118MAPKAPK20.49372025
119MAP3K140.49139840
120ATM0.48988125
121PRKCI0.48826280
122CSNK2A20.48613923
123LYN0.47913896
124CCNB10.47837098
125LCK0.47182176
126MAPK110.46558311
127BMX0.44320367
128DAPK30.42264981
129CSK0.41968057
130ALK0.41808581
131RPS6KC10.41621187
132RPS6KL10.41621187
133HCK0.41294702
134SYK0.40188475
135ITK0.40057212
136ILK0.40032436
137TNK20.38422395
138PTK20.36749000
139PRKG20.35704779
140RAF10.34754005
141MTOR0.33871444
142MOS0.33355561
143MAP3K50.31955878

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.48702723
2Mismatch repair_Homo sapiens_hsa034303.68117113
3Ribosome_Homo sapiens_hsa030103.54769028
4Proteasome_Homo sapiens_hsa030503.00207686
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.98828154
6Spliceosome_Homo sapiens_hsa030402.91787004
7Base excision repair_Homo sapiens_hsa034102.86978179
8RNA polymerase_Homo sapiens_hsa030202.66049981
9Homologous recombination_Homo sapiens_hsa034402.57855646
10RNA transport_Homo sapiens_hsa030132.56399120
11Nucleotide excision repair_Homo sapiens_hsa034202.47601387
12Cell cycle_Homo sapiens_hsa041102.29900892
13Pyrimidine metabolism_Homo sapiens_hsa002402.21103277
14One carbon pool by folate_Homo sapiens_hsa006702.12378954
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.90486714
16Fanconi anemia pathway_Homo sapiens_hsa034601.77324063
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.74989467
18p53 signaling pathway_Homo sapiens_hsa041151.65948079
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61504328
20Non-homologous end-joining_Homo sapiens_hsa034501.59906098
21Basal transcription factors_Homo sapiens_hsa030221.52336957
22RNA degradation_Homo sapiens_hsa030181.51412523
23Lysosome_Homo sapiens_hsa041421.49027462
24Antigen processing and presentation_Homo sapiens_hsa046121.44172023
25Primary immunodeficiency_Homo sapiens_hsa053401.42862654
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.41305949
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39650594
28Herpes simplex infection_Homo sapiens_hsa051681.34166245
29Epstein-Barr virus infection_Homo sapiens_hsa051691.31726684
30mRNA surveillance pathway_Homo sapiens_hsa030151.30040124
31Central carbon metabolism in cancer_Homo sapiens_hsa052301.18971509
32Legionellosis_Homo sapiens_hsa051341.14774394
33Carbon metabolism_Homo sapiens_hsa012001.14590583
34Systemic lupus erythematosus_Homo sapiens_hsa053221.11968843
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.11753436
36Measles_Homo sapiens_hsa051621.05623352
37Viral carcinogenesis_Homo sapiens_hsa052031.05467526
38Purine metabolism_Homo sapiens_hsa002301.01591417
39Vibrio cholerae infection_Homo sapiens_hsa051101.01076288
40Pentose phosphate pathway_Homo sapiens_hsa000301.00601830
41Folate biosynthesis_Homo sapiens_hsa007901.00206649
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99530799
43Leishmaniasis_Homo sapiens_hsa051400.96373807
44Non-small cell lung cancer_Homo sapiens_hsa052230.95842751
45Sulfur relay system_Homo sapiens_hsa041220.94732392
46Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.93242407
47Prion diseases_Homo sapiens_hsa050200.91068766
48Apoptosis_Homo sapiens_hsa042100.89414161
49HTLV-I infection_Homo sapiens_hsa051660.88503240
50Intestinal immune network for IgA production_Homo sapiens_hsa046720.84694502
51Shigellosis_Homo sapiens_hsa051310.84122288
52Hepatitis C_Homo sapiens_hsa051600.81394859
53Selenocompound metabolism_Homo sapiens_hsa004500.77618905
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76144804
55VEGF signaling pathway_Homo sapiens_hsa043700.75877120
56Autoimmune thyroid disease_Homo sapiens_hsa053200.75117007
57Malaria_Homo sapiens_hsa051440.74999707
58Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74572614
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.74118703
60Phagosome_Homo sapiens_hsa041450.74037814
61Staphylococcus aureus infection_Homo sapiens_hsa051500.73622499
62Small cell lung cancer_Homo sapiens_hsa052220.73576478
63RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.72729356
64Hematopoietic cell lineage_Homo sapiens_hsa046400.70273938
65Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.69889426
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68629646
67Influenza A_Homo sapiens_hsa051640.68377297
68Acute myeloid leukemia_Homo sapiens_hsa052210.67690585
69Hepatitis B_Homo sapiens_hsa051610.67162788
70B cell receptor signaling pathway_Homo sapiens_hsa046620.64503308
71Endocytosis_Homo sapiens_hsa041440.64432996
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64031586
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64019651
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62379191
75Thyroid cancer_Homo sapiens_hsa052160.61939315
76Rheumatoid arthritis_Homo sapiens_hsa053230.59142141
77Graft-versus-host disease_Homo sapiens_hsa053320.59105310
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58139807
79Allograft rejection_Homo sapiens_hsa053300.58129597
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57694834
81Chronic myeloid leukemia_Homo sapiens_hsa052200.55414327
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.54521148
83Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.53435724
84Endometrial cancer_Homo sapiens_hsa052130.52947414
85T cell receptor signaling pathway_Homo sapiens_hsa046600.52699852
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51528486
87Notch signaling pathway_Homo sapiens_hsa043300.50686360
88Biosynthesis of amino acids_Homo sapiens_hsa012300.50616343
89MicroRNAs in cancer_Homo sapiens_hsa052060.50398513
90Other glycan degradation_Homo sapiens_hsa005110.50258668
91Osteoclast differentiation_Homo sapiens_hsa043800.49184552
92Fatty acid elongation_Homo sapiens_hsa000620.49145936
93Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48615998
94Protein export_Homo sapiens_hsa030600.48615655
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.47829317
96Toxoplasmosis_Homo sapiens_hsa051450.47644812
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47154587
98Viral myocarditis_Homo sapiens_hsa054160.46860645
99Toll-like receptor signaling pathway_Homo sapiens_hsa046200.46427125
100N-Glycan biosynthesis_Homo sapiens_hsa005100.46326088
101Chemokine signaling pathway_Homo sapiens_hsa040620.45563832
102Asthma_Homo sapiens_hsa053100.44791888
103Glutathione metabolism_Homo sapiens_hsa004800.43695100
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.43328741
105Colorectal cancer_Homo sapiens_hsa052100.42434149
106Vitamin B6 metabolism_Homo sapiens_hsa007500.42283488
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.42156800
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42136266
109Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.42133481
110Bladder cancer_Homo sapiens_hsa052190.39979325
111TNF signaling pathway_Homo sapiens_hsa046680.38874101
112Oocyte meiosis_Homo sapiens_hsa041140.38711255
113Pertussis_Homo sapiens_hsa051330.36720084
114Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36449958
115HIF-1 signaling pathway_Homo sapiens_hsa040660.32029756
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.30243501
117Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30081653
118Tuberculosis_Homo sapiens_hsa051520.29944628
119Fructose and mannose metabolism_Homo sapiens_hsa000510.29676324
120Galactose metabolism_Homo sapiens_hsa000520.29621013
121Salmonella infection_Homo sapiens_hsa051320.28929098
122Pancreatic cancer_Homo sapiens_hsa052120.28285341
123TGF-beta signaling pathway_Homo sapiens_hsa043500.28140297
124Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.27001596
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26705200

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »