Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 4.55576053 |
2 | DNA deamination (GO:0045006) | 4.50740629 |
3 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.34085853 |
4 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.13490222 |
5 | DNA strand elongation (GO:0022616) | 4.12209262 |
6 | viral transcription (GO:0019083) | 4.08742516 |
7 | maturation of SSU-rRNA (GO:0030490) | 3.98910399 |
8 | DNA replication initiation (GO:0006270) | 3.98628186 |
9 | protein maturation by protein folding (GO:0022417) | 3.98162244 |
10 | translational termination (GO:0006415) | 3.98132400 |
11 | COPI coating of Golgi vesicle (GO:0048205) | 3.94002822 |
12 | Golgi transport vesicle coating (GO:0048200) | 3.94002822 |
13 | formation of translation preinitiation complex (GO:0001731) | 3.89896453 |
14 | DNA unwinding involved in DNA replication (GO:0006268) | 3.72135498 |
15 | telomere maintenance via recombination (GO:0000722) | 3.68471681 |
16 | ribosomal small subunit biogenesis (GO:0042274) | 3.68325911 |
17 | DNA replication checkpoint (GO:0000076) | 3.66121758 |
18 | translational elongation (GO:0006414) | 3.64254935 |
19 | ribosomal large subunit biogenesis (GO:0042273) | 3.60325674 |
20 | protein localization to kinetochore (GO:0034501) | 3.56960267 |
21 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.56826244 |
22 | translational initiation (GO:0006413) | 3.56325207 |
23 | pentose-phosphate shunt (GO:0006098) | 3.53371126 |
24 | nucleobase biosynthetic process (GO:0046112) | 3.47986923 |
25 | mitotic recombination (GO:0006312) | 3.43834893 |
26 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.40823462 |
27 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.40166011 |
28 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.39946439 |
29 | mitotic metaphase plate congression (GO:0007080) | 3.33688906 |
30 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.30812907 |
31 | ribosome assembly (GO:0042255) | 3.29712604 |
32 | mitotic nuclear envelope disassembly (GO:0007077) | 3.29575843 |
33 | protein targeting to ER (GO:0045047) | 3.28913823 |
34 | cotranslational protein targeting to membrane (GO:0006613) | 3.28380367 |
35 | ribosome biogenesis (GO:0042254) | 3.27212943 |
36 | telomere maintenance via telomere lengthening (GO:0010833) | 3.26932123 |
37 | purine nucleobase biosynthetic process (GO:0009113) | 3.23734958 |
38 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.23687774 |
39 | GDP-mannose metabolic process (GO:0019673) | 3.20658135 |
40 | protein localization to chromosome, centromeric region (GO:0071459) | 3.19704378 |
41 | NADPH regeneration (GO:0006740) | 3.18555591 |
42 | pinocytosis (GO:0006907) | 3.17943242 |
43 | viral life cycle (GO:0019058) | 3.17671546 |
44 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.15440740 |
45 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.15440740 |
46 | response to peptidoglycan (GO:0032494) | 3.14263810 |
47 | CENP-A containing nucleosome assembly (GO:0034080) | 3.09988940 |
48 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.09853774 |
49 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.09832237 |
50 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.09097383 |
51 | chromatin remodeling at centromere (GO:0031055) | 3.09009887 |
52 | protein localization to endoplasmic reticulum (GO:0070972) | 3.07929565 |
53 | IMP biosynthetic process (GO:0006188) | 3.07386955 |
54 | cellular protein complex disassembly (GO:0043624) | 3.07357328 |
55 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.06468803 |
56 | rRNA processing (GO:0006364) | 3.02448668 |
57 | membrane disassembly (GO:0030397) | 3.02444048 |
58 | nuclear envelope disassembly (GO:0051081) | 3.02444048 |
59 | proline biosynthetic process (GO:0006561) | 3.02314307 |
60 | regulation of superoxide anion generation (GO:0032928) | 3.01826724 |
61 | spliceosomal snRNP assembly (GO:0000387) | 2.97925614 |
62 | rRNA metabolic process (GO:0016072) | 2.92585968 |
63 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.91507702 |
64 | DNA replication-independent nucleosome organization (GO:0034724) | 2.91507702 |
65 | mitotic nuclear envelope reassembly (GO:0007084) | 2.88916756 |
66 | nuclear envelope reassembly (GO:0031468) | 2.88916756 |
67 | glucose catabolic process (GO:0006007) | 2.87949169 |
68 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.85954282 |
69 | positive regulation by symbiont of host defense response (GO:0052509) | 2.85804556 |
70 | modulation by symbiont of host defense response (GO:0052031) | 2.85804556 |
71 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.85804556 |
72 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.85804556 |
73 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.85804556 |
74 | modulation by symbiont of host immune response (GO:0052553) | 2.85804556 |
75 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.85007878 |
76 | pentose metabolic process (GO:0019321) | 2.83717470 |
77 | protein complex disassembly (GO:0043241) | 2.81194255 |
78 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.81180167 |
79 | metaphase plate congression (GO:0051310) | 2.80846193 |
80 | proteasome assembly (GO:0043248) | 2.80413838 |
81 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.80180622 |
82 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.78884625 |
83 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.76964336 |
84 | translation (GO:0006412) | 2.75743645 |
85 | pseudouridine synthesis (GO:0001522) | 2.75572527 |
86 | nuclear pore organization (GO:0006999) | 2.75004654 |
87 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.74032154 |
88 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.73401664 |
89 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.72930404 |
90 | regulation of spindle organization (GO:0090224) | 2.71864314 |
91 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.71813476 |
92 | establishment of chromosome localization (GO:0051303) | 2.68649325 |
93 | IMP metabolic process (GO:0046040) | 2.68635958 |
94 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.66835223 |
95 | mRNA catabolic process (GO:0006402) | 2.66221017 |
96 | RNA catabolic process (GO:0006401) | 2.66136264 |
97 | modulation by virus of host process (GO:0019054) | 2.64685688 |
98 | macromolecular complex disassembly (GO:0032984) | 2.64222798 |
99 | rRNA modification (GO:0000154) | 2.63025487 |
100 | folic acid metabolic process (GO:0046655) | 2.62954321 |
101 | modulation by symbiont of host cellular process (GO:0044068) | 2.62512485 |
102 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.62374426 |
103 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.61983308 |
104 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.61854526 |
105 | negative regulation of ligase activity (GO:0051352) | 2.61790968 |
106 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.61790968 |
107 | pyrimidine nucleoside salvage (GO:0043097) | 2.61492661 |
108 | pyrimidine-containing compound salvage (GO:0008655) | 2.61492661 |
109 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.59943583 |
110 | cell cycle G1/S phase transition (GO:0044843) | 2.59943583 |
111 | kinetochore organization (GO:0051383) | 2.59744292 |
112 | UV protection (GO:0009650) | 2.59473178 |
113 | negative regulation of B cell apoptotic process (GO:0002903) | 2.58818899 |
114 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.57950597 |
115 | negative regulation of RNA splicing (GO:0033119) | 2.57734368 |
116 | DNA duplex unwinding (GO:0032508) | 2.57555752 |
117 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.57527389 |
118 | mitotic sister chromatid segregation (GO:0000070) | 2.56022564 |
119 | DNA geometric change (GO:0032392) | 2.55917241 |
120 | * NIK/NF-kappaB signaling (GO:0038061) | 2.55023945 |
121 | mitotic chromosome condensation (GO:0007076) | 2.54574741 |
122 | viral mRNA export from host cell nucleus (GO:0046784) | 2.54224429 |
123 | telomere maintenance (GO:0000723) | 2.53787332 |
124 | telomere organization (GO:0032200) | 2.53599712 |
125 | neutrophil activation involved in immune response (GO:0002283) | 2.53013813 |
126 | immunoglobulin mediated immune response (GO:0016064) | 2.52711410 |
127 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.52645546 |
128 | histone arginine methylation (GO:0034969) | 2.51494652 |
129 | nuclear pore complex assembly (GO:0051292) | 2.51288007 |
130 | negative regulation of interleukin-12 production (GO:0032695) | 2.51061463 |
131 | RNA splicing, via transesterification reactions (GO:0000375) | 2.50703098 |
132 | mRNA splicing, via spliceosome (GO:0000398) | 2.50358259 |
133 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.50358259 |
134 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.50136474 |
135 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.49741518 |
136 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.49741518 |
137 | histone exchange (GO:0043486) | 2.49649296 |
138 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.49290325 |
139 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.48187251 |
140 | respiratory burst (GO:0045730) | 2.47752475 |
141 | establishment of viral latency (GO:0019043) | 2.47155013 |
142 | negative regulation of chromosome segregation (GO:0051985) | 2.46698746 |
143 | chromatin assembly or disassembly (GO:0006333) | 2.46339437 |
144 | apoptotic process involved in morphogenesis (GO:0060561) | 2.45929687 |
145 | protein localization to endosome (GO:0036010) | 2.45878432 |
146 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.45631744 |
147 | protein retention in ER lumen (GO:0006621) | 2.42848322 |
148 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.42038291 |
149 | T cell apoptotic process (GO:0070231) | 2.41309426 |
150 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.40941615 |
151 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.39936039 |
152 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.39860096 |
153 | regulation of translational termination (GO:0006449) | 2.38804734 |
154 | regulation of defense response to virus by virus (GO:0050690) | 2.37308539 |
155 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.36516818 |
156 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.36213429 |
157 | peptidyl-arginine N-methylation (GO:0035246) | 2.34644318 |
158 | peptidyl-arginine methylation (GO:0018216) | 2.34644318 |
159 | glucose 6-phosphate metabolic process (GO:0051156) | 2.34315446 |
160 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.34131572 |
161 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.34052473 |
162 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.32348781 |
163 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.30572490 |
164 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.30097080 |
165 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.28826069 |
166 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.28138994 |
167 | cellular response to interleukin-4 (GO:0071353) | 2.27862576 |
168 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.27337387 |
169 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.26925321 |
170 | barbed-end actin filament capping (GO:0051016) | 2.26896640 |
171 | virion assembly (GO:0019068) | 2.23982995 |
172 | negative regulation of cell killing (GO:0031342) | 2.23800435 |
173 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.23800435 |
174 | detection of bacterium (GO:0016045) | 2.23728515 |
175 | negative regulation of cell size (GO:0045792) | 2.23547103 |
176 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 2.22174377 |
177 | deoxyribonucleotide catabolic process (GO:0009264) | 2.21798625 |
178 | establishment of integrated proviral latency (GO:0075713) | 2.20799183 |
179 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.20783914 |
180 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.20783914 |
181 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.20679477 |
182 | deoxyribose phosphate catabolic process (GO:0046386) | 2.18723793 |
183 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.17918750 |
184 | nucleotide salvage (GO:0043173) | 2.16948231 |
185 | detection of other organism (GO:0098543) | 2.16880186 |
186 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.16393755 |
187 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.15528269 |
188 | maternal placenta development (GO:0001893) | 2.15017375 |
189 | amyloid precursor protein catabolic process (GO:0042987) | 2.14613626 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.24510241 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.80642398 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.61387092 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.39519734 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.98594726 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.74049685 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.70374674 |
8 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.56001810 |
9 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.51575487 |
10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.50506874 |
11 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.47049761 |
12 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.46638080 |
13 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.44728212 |
14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.42700895 |
15 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.25585656 |
16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.18654771 |
17 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.17595334 |
18 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.12473523 |
19 | MYC_22102868_ChIP-Seq_BL_Human | 2.08228726 |
20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.05465506 |
21 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.02810572 |
22 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.01899872 |
23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98974791 |
24 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.96504850 |
25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.95849163 |
26 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.94418411 |
27 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.93883717 |
28 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.89866833 |
29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.84452928 |
30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.80340824 |
31 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79686447 |
32 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.79298689 |
33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.77980022 |
34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.77078801 |
35 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.72938148 |
36 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.72821748 |
37 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.67545349 |
38 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.65571459 |
39 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.64412562 |
40 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.62338756 |
41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.61405439 |
42 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.60170655 |
43 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.59319121 |
44 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.59199054 |
45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.58519720 |
46 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.57468454 |
47 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.57410164 |
48 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56565454 |
49 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.56281738 |
50 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.55954740 |
51 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.54193637 |
52 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.53436108 |
53 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48453491 |
54 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.47801031 |
55 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.44844651 |
56 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41925068 |
57 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.41592850 |
58 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.40967815 |
59 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.40303752 |
60 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.39973126 |
61 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.39781897 |
62 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.39316775 |
63 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.38470234 |
64 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.37776099 |
65 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.37343813 |
66 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.35701958 |
67 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.34563587 |
68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33653528 |
69 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.33507518 |
70 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.32999966 |
71 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.32378981 |
72 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.31855010 |
73 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.30266223 |
74 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.29938251 |
75 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.27291209 |
76 | P68_20966046_ChIP-Seq_HELA_Human | 1.26790739 |
77 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.26264924 |
78 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.26061107 |
79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.25734786 |
80 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.24261072 |
81 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.23967649 |
82 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.22962341 |
83 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.21284259 |
84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.20475416 |
85 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.19497274 |
86 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.18728756 |
87 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.18057471 |
88 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.16976567 |
89 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.16424909 |
90 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.15369466 |
91 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.14438908 |
92 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.14348356 |
93 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.13960001 |
94 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.13950584 |
95 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.12802961 |
96 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12325625 |
97 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.12271066 |
98 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.10921784 |
99 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.10057377 |
100 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.09712694 |
101 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.09387360 |
102 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09325990 |
103 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.09275357 |
104 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08980431 |
105 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.07883107 |
106 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.07685343 |
107 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.06704474 |
108 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06428494 |
109 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.05821389 |
110 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.05770201 |
111 | MAF_26560356_Chip-Seq_TH1_Human | 1.05336872 |
112 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.05120916 |
113 | ATF3_27146783_Chip-Seq_COLON_Human | 1.04469276 |
114 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03970419 |
115 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.03714672 |
116 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03672517 |
117 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03666368 |
118 | UTX_26944678_Chip-Seq_JUKART_Human | 1.01183660 |
119 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.01135437 |
120 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00701416 |
121 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99387332 |
122 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.98112693 |
123 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.97931780 |
124 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.97677216 |
125 | MYB_26560356_Chip-Seq_TH2_Human | 0.96625417 |
126 | MYB_26560356_Chip-Seq_TH1_Human | 0.96621261 |
127 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96218976 |
128 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.94858398 |
129 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.94043101 |
130 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93159748 |
131 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.92441893 |
132 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90974362 |
133 | MAF_26560356_Chip-Seq_TH2_Human | 0.89587673 |
134 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.88741481 |
135 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.88292618 |
136 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.85002826 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.66792703 |
2 | MP0003111_abnormal_nucleus_morphology | 3.58756640 |
3 | * MP0004957_abnormal_blastocyst_morpholog | 3.44083951 |
4 | MP0010094_abnormal_chromosome_stability | 3.40348940 |
5 | MP0005058_abnormal_lysosome_morphology | 3.39465181 |
6 | * MP0003077_abnormal_cell_cycle | 3.18746404 |
7 | MP0008057_abnormal_DNA_replication | 2.92733071 |
8 | MP0005451_abnormal_body_composition | 2.85642702 |
9 | MP0008058_abnormal_DNA_repair | 2.62296803 |
10 | MP0008007_abnormal_cellular_replicative | 2.51126754 |
11 | MP0008260_abnormal_autophagy | 2.44201488 |
12 | MP0002396_abnormal_hematopoietic_system | 2.38538717 |
13 | MP0010352_gastrointestinal_tract_polyps | 2.26897452 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.11953760 |
15 | MP0000490_abnormal_crypts_of | 2.04690914 |
16 | MP0009333_abnormal_splenocyte_physiolog | 2.03633047 |
17 | MP0002877_abnormal_melanocyte_morpholog | 2.01143341 |
18 | MP0001835_abnormal_antigen_presentation | 1.96133241 |
19 | MP0008932_abnormal_embryonic_tissue | 1.95272890 |
20 | MP0003763_abnormal_thymus_physiology | 1.93782592 |
21 | MP0003172_abnormal_lysosome_physiology | 1.92251067 |
22 | MP0000350_abnormal_cell_proliferation | 1.82930079 |
23 | MP0001730_embryonic_growth_arrest | 1.77219589 |
24 | MP0000685_abnormal_immune_system | 1.72670274 |
25 | MP0003436_decreased_susceptibility_to | 1.70492416 |
26 | MP0001849_ear_inflammation | 1.70323571 |
27 | * MP0002398_abnormal_bone_marrow | 1.65759313 |
28 | MP0004808_abnormal_hematopoietic_stem | 1.64152108 |
29 | MP0003786_premature_aging | 1.60018443 |
30 | MP0010307_abnormal_tumor_latency | 1.58661034 |
31 | MP0001800_abnormal_humoral_immune | 1.56269146 |
32 | MP0003300_gastrointestinal_ulcer | 1.54981236 |
33 | MP0002254_reproductive_system_inflammat | 1.54795181 |
34 | MP0001545_abnormal_hematopoietic_system | 1.52064015 |
35 | MP0005397_hematopoietic_system_phenotyp | 1.52064015 |
36 | MP0002019_abnormal_tumor_incidence | 1.50990560 |
37 | MP0002722_abnormal_immune_system | 1.50899560 |
38 | MP0010234_abnormal_vibrissa_follicle | 1.50294583 |
39 | MP0005671_abnormal_response_to | 1.49757114 |
40 | MP0003123_paternal_imprinting | 1.49729012 |
41 | MP0000689_abnormal_spleen_morphology | 1.49042602 |
42 | MP0003453_abnormal_keratinocyte_physiol | 1.48004197 |
43 | MP0009785_altered_susceptibility_to | 1.46505814 |
44 | MP0004858_abnormal_nervous_system | 1.45948744 |
45 | MP0002796_impaired_skin_barrier | 1.45116167 |
46 | MP0002452_abnormal_antigen_presenting | 1.44966293 |
47 | MP0000858_altered_metastatic_potential | 1.44886538 |
48 | MP0004185_abnormal_adipocyte_glucose | 1.44326625 |
49 | MP0000703_abnormal_thymus_morphology | 1.40269940 |
50 | MP0005501_abnormal_skin_physiology | 1.39400321 |
51 | MP0001853_heart_inflammation | 1.38014313 |
52 | * MP0002420_abnormal_adaptive_immunity | 1.37648186 |
53 | * MP0001819_abnormal_immune_cell | 1.37176821 |
54 | MP0002405_respiratory_system_inflammati | 1.35625789 |
55 | * MP0000716_abnormal_immune_system | 1.33442368 |
56 | MP0005025_abnormal_response_to | 1.33428626 |
57 | MP0005000_abnormal_immune_tolerance | 1.33378493 |
58 | MP0000313_abnormal_cell_death | 1.33204646 |
59 | MP0002723_abnormal_immune_serum | 1.33008838 |
60 | * MP0002429_abnormal_blood_cell | 1.32842800 |
61 | MP0001672_abnormal_embryogenesis/_devel | 1.31839039 |
62 | MP0005380_embryogenesis_phenotype | 1.31839039 |
63 | MP0009278_abnormal_bone_marrow | 1.31192563 |
64 | MP0001697_abnormal_embryo_size | 1.29486502 |
65 | * MP0002080_prenatal_lethality | 1.24909606 |
66 | MP0010155_abnormal_intestine_physiology | 1.18436344 |
67 | MP0003984_embryonic_growth_retardation | 1.17468193 |
68 | MP0002088_abnormal_embryonic_growth/wei | 1.15669979 |
69 | MP0003075_altered_response_to | 1.15667413 |
70 | MP0000343_altered_response_to | 1.15063962 |
71 | MP0005076_abnormal_cell_differentiation | 1.13560227 |
72 | MP0003303_peritoneal_inflammation | 1.13463934 |
73 | MP0002086_abnormal_extraembryonic_tissu | 1.12087294 |
74 | MP0000678_abnormal_parathyroid_gland | 1.09417627 |
75 | MP0003718_maternal_effect | 1.08646830 |
76 | MP0001790_abnormal_immune_system | 1.08061324 |
77 | MP0005387_immune_system_phenotype | 1.08061324 |
78 | MP0002132_abnormal_respiratory_system | 1.08056755 |
79 | MP0002148_abnormal_hypersensitivity_rea | 1.06154402 |
80 | MP0003567_abnormal_fetal_cardiomyocyte | 1.05143550 |
81 | MP0002419_abnormal_innate_immunity | 1.04301006 |
82 | * MP0002085_abnormal_embryonic_tissue | 1.04242896 |
83 | MP0008877_abnormal_DNA_methylation | 1.03921299 |
84 | MP0002166_altered_tumor_susceptibility | 1.03344834 |
85 | MP0003448_altered_tumor_morphology | 1.03024795 |
86 | MP0002006_tumorigenesis | 1.01437238 |
87 | MP0004197_abnormal_fetal_growth/weight/ | 0.99099749 |
88 | MP0003186_abnormal_redox_activity | 0.99090360 |
89 | MP0006054_spinal_hemorrhage | 0.98166340 |
90 | MP0000465_gastrointestinal_hemorrhage | 0.96827547 |
91 | MP0005023_abnormal_wound_healing | 0.96398697 |
92 | MP0004233_abnormal_muscle_weight | 0.95693981 |
93 | MP0001727_abnormal_embryo_implantation | 0.95340624 |
94 | MP0005075_abnormal_melanosome_morpholog | 0.94170122 |
95 | MP0005464_abnormal_platelet_physiology | 0.93647525 |
96 | MP0009840_abnormal_foam_cell | 0.93508010 |
97 | MP0004510_myositis | 0.93371503 |
98 | MP0003806_abnormal_nucleotide_metabolis | 0.93184724 |
99 | MP0002084_abnormal_developmental_patter | 0.92172566 |
100 | MP0001873_stomach_inflammation | 0.90958038 |
101 | MP0006035_abnormal_mitochondrial_morpho | 0.90894340 |
102 | MP0001845_abnormal_inflammatory_respons | 0.89090288 |
103 | MP0005174_abnormal_tail_pigmentation | 0.87815427 |
104 | MP0004947_skin_inflammation | 0.87513151 |
105 | MP0010030_abnormal_orbit_morphology | 0.86850994 |
106 | MP0003315_abnormal_perineum_morphology | 0.84457620 |
107 | MP0000477_abnormal_intestine_morphology | 0.83882763 |
108 | MP0009764_decreased_sensitivity_to | 0.83868905 |
109 | MP0003221_abnormal_cardiomyocyte_apopto | 0.82788155 |
110 | MP0003866_abnormal_defecation | 0.82093086 |
111 | MP0004264_abnormal_extraembryonic_tissu | 0.81271598 |
112 | MP0001216_abnormal_epidermal_layer | 0.80756644 |
113 | MP0002998_abnormal_bone_remodeling | 0.80385255 |
114 | MP0002210_abnormal_sex_determination | 0.78803156 |
115 | MP0002089_abnormal_postnatal_growth/wei | 0.77968684 |
116 | MP0009931_abnormal_skin_appearance | 0.77195155 |
117 | MP0005083_abnormal_biliary_tract | 0.76790290 |
118 | MP0005390_skeleton_phenotype | 0.76202585 |
119 | MP0003566_abnormal_cell_adhesion | 0.75067189 |
120 | MP0006082_CNS_inflammation | 0.74762991 |
121 | MP0001293_anophthalmia | 0.74742373 |
122 | MP0000604_amyloidosis | 0.74698381 |
123 | MP0001145_abnormal_male_reproductive | 0.72924474 |
124 | MP0003705_abnormal_hypodermis_morpholog | 0.71855931 |
125 | * MP0000358_abnormal_cell_content/ | 0.71403728 |
126 | MP0003724_increased_susceptibility_to | 0.66881985 |
127 | MP0005621_abnormal_cell_physiology | 0.66781100 |
128 | MP0001533_abnormal_skeleton_physiology | 0.64772560 |
129 | * MP0005384_cellular_phenotype | 0.63776583 |
130 | MP0008469_abnormal_protein_level | 0.63533982 |
131 | MP0001119_abnormal_female_reproductive | 0.62935963 |
132 | MP0000371_diluted_coat_color | 0.62658901 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.30614253 |
2 | Reticulocytopenia (HP:0001896) | 4.24683717 |
3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.24514039 |
4 | Abnormal number of erythroid precursors (HP:0012131) | 4.05071535 |
5 | Abnormality of macrophages (HP:0004311) | 3.47770710 |
6 | Breast hypoplasia (HP:0003187) | 3.35363257 |
7 | Oral leukoplakia (HP:0002745) | 3.10656394 |
8 | Vertebral compression fractures (HP:0002953) | 3.08785556 |
9 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.07392768 |
10 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.07392768 |
11 | Abnormality of glycolipid metabolism (HP:0010969) | 3.07392768 |
12 | Cholecystitis (HP:0001082) | 3.06279829 |
13 | Abnormal gallbladder physiology (HP:0012438) | 3.06279829 |
14 | Increased serum ferritin (HP:0003281) | 3.01432855 |
15 | Aplastic anemia (HP:0001915) | 3.00526139 |
16 | Selective tooth agenesis (HP:0001592) | 2.96302028 |
17 | Abnormality of the anterior horn cell (HP:0006802) | 2.95261148 |
18 | Degeneration of anterior horn cells (HP:0002398) | 2.95261148 |
19 | IgM deficiency (HP:0002850) | 2.88829376 |
20 | Ragged-red muscle fibers (HP:0003200) | 2.85071040 |
21 | Pallor (HP:0000980) | 2.83886613 |
22 | Thrombocytosis (HP:0001894) | 2.83823257 |
23 | Macrocytic anemia (HP:0001972) | 2.80150706 |
24 | Increased cerebral lipofuscin (HP:0011813) | 2.76969809 |
25 | Colon cancer (HP:0003003) | 2.76828759 |
26 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.74151858 |
27 | Patellar aplasia (HP:0006443) | 2.70846873 |
28 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.70427204 |
29 | Chromsome breakage (HP:0040012) | 2.70163167 |
30 | Trismus (HP:0000211) | 2.65355802 |
31 | Carpal bone hypoplasia (HP:0001498) | 2.64806114 |
32 | Hypertensive crisis (HP:0100735) | 2.64172761 |
33 | Hepatosplenomegaly (HP:0001433) | 2.62467859 |
34 | Absent thumb (HP:0009777) | 2.58454722 |
35 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.56818982 |
36 | Agnosia (HP:0010524) | 2.55801518 |
37 | Multiple enchondromatosis (HP:0005701) | 2.54248577 |
38 | Purpura (HP:0000979) | 2.54155747 |
39 | Rough bone trabeculation (HP:0100670) | 2.51152230 |
40 | Dysostosis multiplex (HP:0000943) | 2.49398478 |
41 | Vacuolated lymphocytes (HP:0001922) | 2.49314114 |
42 | Microretrognathia (HP:0000308) | 2.48362272 |
43 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.46023231 |
44 | Recurrent abscess formation (HP:0002722) | 2.45439862 |
45 | Meckel diverticulum (HP:0002245) | 2.41586582 |
46 | Myelodysplasia (HP:0002863) | 2.37851462 |
47 | Increased IgM level (HP:0003496) | 2.34781154 |
48 | Progressive muscle weakness (HP:0003323) | 2.33844417 |
49 | Abnormality of T cell physiology (HP:0011840) | 2.32181503 |
50 | Abnormality of the ileum (HP:0001549) | 2.32092759 |
51 | Abnormality of the preputium (HP:0100587) | 2.29971038 |
52 | Neoplasm of the pancreas (HP:0002894) | 2.29194172 |
53 | Eczematoid dermatitis (HP:0000976) | 2.27736231 |
54 | Loss of speech (HP:0002371) | 2.27388515 |
55 | Medulloblastoma (HP:0002885) | 2.26518731 |
56 | Abnormality of T cells (HP:0002843) | 2.26282266 |
57 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.25334542 |
58 | Basal cell carcinoma (HP:0002671) | 2.24894940 |
59 | Myositis (HP:0100614) | 2.24479888 |
60 | Pustule (HP:0200039) | 2.24120079 |
61 | Achilles tendon contracture (HP:0001771) | 2.24083658 |
62 | Bone marrow hypocellularity (HP:0005528) | 2.21266172 |
63 | 11 pairs of ribs (HP:0000878) | 2.20896356 |
64 | Lymphoma (HP:0002665) | 2.17931055 |
65 | Petechiae (HP:0000967) | 2.16344167 |
66 | Abnormality of chromosome stability (HP:0003220) | 2.16193989 |
67 | J-shaped sella turcica (HP:0002680) | 2.15576537 |
68 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.13051278 |
69 | Premature graying of hair (HP:0002216) | 2.12228297 |
70 | Distal lower limb muscle weakness (HP:0009053) | 2.11501187 |
71 | Recurrent viral infections (HP:0004429) | 2.10247320 |
72 | Abnormality of iron homeostasis (HP:0011031) | 2.10032981 |
73 | Broad distal phalanx of finger (HP:0009836) | 2.09728339 |
74 | Ependymoma (HP:0002888) | 2.08809280 |
75 | Cellular immunodeficiency (HP:0005374) | 2.08719372 |
76 | Increased IgE level (HP:0003212) | 2.06428674 |
77 | Microvesicular hepatic steatosis (HP:0001414) | 2.05196093 |
78 | Cleft eyelid (HP:0000625) | 2.04497777 |
79 | Tracheoesophageal fistula (HP:0002575) | 2.04490023 |
80 | Type I transferrin isoform profile (HP:0003642) | 2.03344673 |
81 | Abnormality of the Achilles tendon (HP:0005109) | 2.01932690 |
82 | Recurrent fungal infections (HP:0002841) | 2.01754525 |
83 | Amaurosis fugax (HP:0100576) | 2.01160803 |
84 | Distal lower limb amyotrophy (HP:0008944) | 1.98570055 |
85 | Hyperacusis (HP:0010780) | 1.97704437 |
86 | Premature ovarian failure (HP:0008209) | 1.97265361 |
87 | Chronic otitis media (HP:0000389) | 1.97264364 |
88 | Long palpebral fissure (HP:0000637) | 1.96778312 |
89 | Recurrent bronchitis (HP:0002837) | 1.94610426 |
90 | Recurrent bacterial skin infections (HP:0005406) | 1.94400216 |
91 | Impulsivity (HP:0100710) | 1.93746694 |
92 | Absent radius (HP:0003974) | 1.93630052 |
93 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.93581309 |
94 | IgG deficiency (HP:0004315) | 1.93364771 |
95 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.93349816 |
96 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.93349816 |
97 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.93349816 |
98 | Slender long bone (HP:0003100) | 1.93227986 |
99 | Systemic lupus erythematosus (HP:0002725) | 1.92817990 |
100 | Meningitis (HP:0001287) | 1.91112696 |
101 | Progressive neurologic deterioration (HP:0002344) | 1.90905849 |
102 | Prolonged neonatal jaundice (HP:0006579) | 1.90292893 |
103 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.89207710 |
104 | Mediastinal lymphadenopathy (HP:0100721) | 1.88986917 |
105 | Duodenal stenosis (HP:0100867) | 1.88488265 |
106 | Small intestinal stenosis (HP:0012848) | 1.88488265 |
107 | Combined immunodeficiency (HP:0005387) | 1.88357990 |
108 | Urticaria (HP:0001025) | 1.87299076 |
109 | Testicular atrophy (HP:0000029) | 1.86906095 |
110 | Abnormality of the umbilical cord (HP:0010881) | 1.86288680 |
111 | T lymphocytopenia (HP:0005403) | 1.85206110 |
112 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.85058615 |
113 | Premature rupture of membranes (HP:0001788) | 1.84854068 |
114 | Cerebral hypomyelination (HP:0006808) | 1.83704684 |
115 | Gastrointestinal inflammation (HP:0004386) | 1.83362515 |
116 | Biconcave vertebral bodies (HP:0004586) | 1.82398819 |
117 | Poor head control (HP:0002421) | 1.82102823 |
118 | Panhypogammaglobulinemia (HP:0003139) | 1.82028316 |
119 | Poikiloderma (HP:0001029) | 1.81191379 |
120 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.81140333 |
121 | Mucopolysacchariduria (HP:0008155) | 1.81140333 |
122 | Abnormal trabecular bone morphology (HP:0100671) | 1.80251823 |
123 | Squamous cell carcinoma (HP:0002860) | 1.78832385 |
124 | Upper motor neuron abnormality (HP:0002127) | 1.78700184 |
125 | Axonal loss (HP:0003447) | 1.78310203 |
126 | Pancytopenia (HP:0001876) | 1.78260935 |
127 | Orchitis (HP:0100796) | 1.78026460 |
128 | Granulocytopenia (HP:0001913) | 1.77853744 |
129 | Seborrheic dermatitis (HP:0001051) | 1.77068595 |
130 | Abnormality of T cell number (HP:0011839) | 1.76955690 |
131 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.76214425 |
132 | Cervical subluxation (HP:0003308) | 1.75185416 |
133 | Atresia of the external auditory canal (HP:0000413) | 1.75080150 |
134 | Absent forearm bone (HP:0003953) | 1.74043330 |
135 | Aplasia involving forearm bones (HP:0009822) | 1.74043330 |
136 | Gastrointestinal dysmotility (HP:0002579) | 1.73388467 |
137 | Abnormal number of incisors (HP:0011064) | 1.73302881 |
138 | Hemorrhage of the eye (HP:0011885) | 1.73109096 |
139 | Reduced antithrombin III activity (HP:0001976) | 1.72838513 |
140 | Fasciculations (HP:0002380) | 1.72804523 |
141 | Muscle fiber atrophy (HP:0100295) | 1.72539557 |
142 | Obstructive lung disease (HP:0006536) | 1.72438501 |
143 | Chronic obstructive pulmonary disease (HP:0006510) | 1.72438501 |
144 | Polygenic inheritance (HP:0010982) | 1.72168918 |
145 | Leukopenia (HP:0001882) | 1.72118031 |
146 | Hypertriglyceridemia (HP:0002155) | 1.70822646 |
147 | Nonimmune hydrops fetalis (HP:0001790) | 1.70352508 |
148 | Pulmonary fibrosis (HP:0002206) | 1.70069926 |
149 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.69961622 |
150 | Nasal polyposis (HP:0100582) | 1.69719844 |
151 | Triphalangeal thumb (HP:0001199) | 1.69289126 |
152 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.69145556 |
153 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.68950582 |
154 | Prominent nose (HP:0000448) | 1.68864917 |
155 | Secondary amenorrhea (HP:0000869) | 1.68701625 |
156 | Overlapping toe (HP:0001845) | 1.67926854 |
157 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.67918765 |
158 | Reticulocytosis (HP:0001923) | 1.67364977 |
159 | Deep venous thrombosis (HP:0002625) | 1.66933346 |
160 | Orthostatic hypotension (HP:0001278) | 1.65942410 |
161 | Cholelithiasis (HP:0001081) | 1.65760022 |
162 | Cellulitis (HP:0100658) | 1.65534294 |
163 | Sloping forehead (HP:0000340) | 1.65481241 |
164 | Progressive external ophthalmoplegia (HP:0000590) | 1.64671296 |
165 | Increased connective tissue (HP:0009025) | 1.60462713 |
166 | Recurrent skin infections (HP:0001581) | 1.59355018 |
167 | Gingivitis (HP:0000230) | 1.59118289 |
168 | Micronodular cirrhosis (HP:0001413) | 1.58783422 |
169 | Hyperparathyroidism (HP:0000843) | 1.58347216 |
170 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.57847039 |
171 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.57847039 |
172 | Single umbilical artery (HP:0001195) | 1.57847039 |
173 | Premature skin wrinkling (HP:0100678) | 1.57679324 |
174 | Agammaglobulinemia (HP:0004432) | 1.57069432 |
175 | Hypergammaglobulinemia (HP:0010702) | 1.56417684 |
176 | Growth hormone excess (HP:0000845) | 1.56066667 |
177 | Thoracic kyphosis (HP:0002942) | 1.55130413 |
178 | Broad face (HP:0000283) | 1.55046278 |
179 | Colitis (HP:0002583) | 1.54910264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.19672367 |
2 | WEE1 | 3.30427997 |
3 | SMG1 | 3.09873854 |
4 | NME2 | 2.87300696 |
5 | CDC7 | 2.65700952 |
6 | VRK2 | 2.64994015 |
7 | EIF2AK1 | 2.47056619 |
8 | NEK2 | 2.41018965 |
9 | TESK2 | 2.33683330 |
10 | MAP4K1 | 2.28584583 |
11 | RPS6KA4 | 1.98943922 |
12 | EIF2AK3 | 1.90289714 |
13 | MAP3K10 | 1.84834957 |
14 | PRPF4B | 1.79960852 |
15 | SIK1 | 1.78046190 |
16 | TLK1 | 1.77878368 |
17 | STK16 | 1.76611600 |
18 | TAOK2 | 1.72097572 |
19 | SRPK1 | 1.71314434 |
20 | PLK4 | 1.68274669 |
21 | EEF2K | 1.68186950 |
22 | ARAF | 1.64915069 |
23 | STK10 | 1.64427893 |
24 | EPHA2 | 1.63838891 |
25 | ACVR1B | 1.63059578 |
26 | DYRK3 | 1.62116571 |
27 | TTK | 1.61732343 |
28 | RPS6KB2 | 1.58933787 |
29 | BCKDK | 1.57252459 |
30 | KDR | 1.55981025 |
31 | CDK7 | 1.53632918 |
32 | BLK | 1.53310442 |
33 | PASK | 1.49200486 |
34 | PLK1 | 1.46919985 |
35 | PIM2 | 1.43776443 |
36 | BRSK2 | 1.43243089 |
37 | TSSK6 | 1.42791009 |
38 | VRK1 | 1.38275174 |
39 | MAP3K8 | 1.33676595 |
40 | PAK4 | 1.33358380 |
41 | CDK4 | 1.31754975 |
42 | TAOK1 | 1.30705089 |
43 | TYK2 | 1.28854013 |
44 | AURKB | 1.28659514 |
45 | ATR | 1.28111738 |
46 | RIPK4 | 1.26929855 |
47 | ICK | 1.25754098 |
48 | SCYL2 | 1.24337409 |
49 | PIM1 | 1.20825962 |
50 | IRAK4 | 1.20485793 |
51 | TESK1 | 1.18971422 |
52 | FLT3 | 1.18963452 |
53 | ZAP70 | 1.15051316 |
54 | JAK3 | 1.11848642 |
55 | LRRK2 | 1.09187731 |
56 | STK4 | 1.08383583 |
57 | SIK3 | 1.06759511 |
58 | MAP2K3 | 1.05654335 |
59 | CDK12 | 1.03791981 |
60 | MAP3K11 | 1.01528196 |
61 | BTK | 1.00975655 |
62 | MKNK1 | 1.00296648 |
63 | CHEK2 | 0.97079271 |
64 | AURKA | 0.95120897 |
65 | GRK6 | 0.94864206 |
66 | NEK1 | 0.94568019 |
67 | ZAK | 0.92834659 |
68 | LIMK1 | 0.92784153 |
69 | TXK | 0.92617005 |
70 | IRAK3 | 0.92150561 |
71 | TGFBR1 | 0.91409390 |
72 | PTK6 | 0.90805574 |
73 | PKN2 | 0.90221416 |
74 | FGFR4 | 0.89261747 |
75 | KIT | 0.87101750 |
76 | MAPKAPK3 | 0.85476568 |
77 | TBK1 | 0.83978661 |
78 | IKBKB | 0.83773869 |
79 | MAP3K13 | 0.83501637 |
80 | MAP3K1 | 0.83153665 |
81 | TEC | 0.82859258 |
82 | CHEK1 | 0.81449385 |
83 | ABL2 | 0.79381836 |
84 | CSF1R | 0.77516832 |
85 | TRIB3 | 0.77201836 |
86 | ERN1 | 0.74133258 |
87 | BRSK1 | 0.71796136 |
88 | MKNK2 | 0.71225548 |
89 | PLK3 | 0.70627658 |
90 | RIPK1 | 0.69853940 |
91 | EPHB1 | 0.69230582 |
92 | MAP3K3 | 0.69073139 |
93 | IRAK2 | 0.65962153 |
94 | PAK1 | 0.65239715 |
95 | MAP2K2 | 0.65225130 |
96 | PRKD2 | 0.62335004 |
97 | EIF2AK2 | 0.61234383 |
98 | KSR2 | 0.59259617 |
99 | TTN | 0.58743788 |
100 | IKBKE | 0.58513406 |
101 | FGR | 0.57699310 |
102 | PBK | 0.57657917 |
103 | CHUK | 0.57352428 |
104 | NLK | 0.57041013 |
105 | RPS6KA5 | 0.55780315 |
106 | DAPK1 | 0.54755392 |
107 | CDK2 | 0.54314601 |
108 | PDPK1 | 0.54246883 |
109 | CDK6 | 0.53993920 |
110 | MATK | 0.52459263 |
111 | MST4 | 0.52362389 |
112 | CLK1 | 0.51632751 |
113 | CSNK2A1 | 0.51113072 |
114 | BRAF | 0.50883132 |
115 | MARK3 | 0.50654651 |
116 | CDK8 | 0.50012707 |
117 | FES | 0.49440909 |
118 | MAPKAPK2 | 0.49372025 |
119 | MAP3K14 | 0.49139840 |
120 | ATM | 0.48988125 |
121 | PRKCI | 0.48826280 |
122 | CSNK2A2 | 0.48613923 |
123 | LYN | 0.47913896 |
124 | CCNB1 | 0.47837098 |
125 | LCK | 0.47182176 |
126 | MAPK11 | 0.46558311 |
127 | BMX | 0.44320367 |
128 | DAPK3 | 0.42264981 |
129 | CSK | 0.41968057 |
130 | ALK | 0.41808581 |
131 | RPS6KL1 | 0.41621187 |
132 | RPS6KC1 | 0.41621187 |
133 | HCK | 0.41294702 |
134 | SYK | 0.40188475 |
135 | ITK | 0.40057212 |
136 | ILK | 0.40032436 |
137 | TNK2 | 0.38422395 |
138 | PTK2 | 0.36749000 |
139 | PRKG2 | 0.35704779 |
140 | RAF1 | 0.34754005 |
141 | MTOR | 0.33871444 |
142 | MOS | 0.33355561 |
143 | MAP3K5 | 0.31955878 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.48702723 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.68117113 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.54769028 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.00207686 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.98828154 |
6 | Spliceosome_Homo sapiens_hsa03040 | 2.91787004 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.86978179 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.66049981 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.57855646 |
10 | RNA transport_Homo sapiens_hsa03013 | 2.56399120 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.47601387 |
12 | Cell cycle_Homo sapiens_hsa04110 | 2.29900892 |
13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.21103277 |
14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.12378954 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.90486714 |
16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77324063 |
17 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.74989467 |
18 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.65948079 |
19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.61504328 |
20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.59906098 |
21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.52336957 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.51412523 |
23 | Lysosome_Homo sapiens_hsa04142 | 1.49027462 |
24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.44172023 |
25 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.42862654 |
26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.41305949 |
27 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.39650594 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.34166245 |
29 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.31726684 |
30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.30040124 |
31 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.18971509 |
32 | Legionellosis_Homo sapiens_hsa05134 | 1.14774394 |
33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.14590583 |
34 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.11968843 |
35 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.11753436 |
36 | Measles_Homo sapiens_hsa05162 | 1.05623352 |
37 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.05467526 |
38 | Purine metabolism_Homo sapiens_hsa00230 | 1.01591417 |
39 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.01076288 |
40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.00601830 |
41 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00206649 |
42 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.99530799 |
43 | Leishmaniasis_Homo sapiens_hsa05140 | 0.96373807 |
44 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.95842751 |
45 | Sulfur relay system_Homo sapiens_hsa04122 | 0.94732392 |
46 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.93242407 |
47 | Prion diseases_Homo sapiens_hsa05020 | 0.91068766 |
48 | Apoptosis_Homo sapiens_hsa04210 | 0.89414161 |
49 | HTLV-I infection_Homo sapiens_hsa05166 | 0.88503240 |
50 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.84694502 |
51 | Shigellosis_Homo sapiens_hsa05131 | 0.84122288 |
52 | Hepatitis C_Homo sapiens_hsa05160 | 0.81394859 |
53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.77618905 |
54 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.76144804 |
55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.75877120 |
56 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.75117007 |
57 | Malaria_Homo sapiens_hsa05144 | 0.74999707 |
58 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.74572614 |
59 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74118703 |
60 | Phagosome_Homo sapiens_hsa04145 | 0.74037814 |
61 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.73622499 |
62 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.73576478 |
63 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.72729356 |
64 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.70273938 |
65 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.69889426 |
66 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.68629646 |
67 | Influenza A_Homo sapiens_hsa05164 | 0.68377297 |
68 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.67690585 |
69 | Hepatitis B_Homo sapiens_hsa05161 | 0.67162788 |
70 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.64503308 |
71 | Endocytosis_Homo sapiens_hsa04144 | 0.64432996 |
72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.64031586 |
73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.64019651 |
74 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62379191 |
75 | Thyroid cancer_Homo sapiens_hsa05216 | 0.61939315 |
76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59142141 |
77 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.59105310 |
78 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.58139807 |
79 | Allograft rejection_Homo sapiens_hsa05330 | 0.58129597 |
80 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.57694834 |
81 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.55414327 |
82 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54521148 |
83 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.53435724 |
84 | Endometrial cancer_Homo sapiens_hsa05213 | 0.52947414 |
85 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.52699852 |
86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51528486 |
87 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.50686360 |
88 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.50616343 |
89 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.50398513 |
90 | Other glycan degradation_Homo sapiens_hsa00511 | 0.50258668 |
91 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.49184552 |
92 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.49145936 |
93 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.48615998 |
94 | Protein export_Homo sapiens_hsa03060 | 0.48615655 |
95 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.47829317 |
96 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.47644812 |
97 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.47154587 |
98 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46860645 |
99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.46427125 |
100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46326088 |
101 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.45563832 |
102 | Asthma_Homo sapiens_hsa05310 | 0.44791888 |
103 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.43695100 |
104 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43328741 |
105 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42434149 |
106 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.42283488 |
107 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.42156800 |
108 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42136266 |
109 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.42133481 |
110 | Bladder cancer_Homo sapiens_hsa05219 | 0.39979325 |
111 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.38874101 |
112 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.38711255 |
113 | Pertussis_Homo sapiens_hsa05133 | 0.36720084 |
114 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.36449958 |
115 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.32029756 |
116 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30243501 |
117 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.30081653 |
118 | Tuberculosis_Homo sapiens_hsa05152 | 0.29944628 |
119 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.29676324 |
120 | Galactose metabolism_Homo sapiens_hsa00052 | 0.29621013 |
121 | Salmonella infection_Homo sapiens_hsa05132 | 0.28929098 |
122 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.28285341 |
123 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.28140297 |
124 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.27001596 |
125 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.26705200 |