

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation by symbiont of host defense response (GO:0052509) | 5.53663482 |
| 2 | modulation by symbiont of host defense response (GO:0052031) | 5.53663482 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.53663482 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.53663482 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.53663482 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.53663482 |
| 7 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.33443784 |
| 8 | detection of molecule of bacterial origin (GO:0032490) | 5.22878299 |
| 9 | response to peptidoglycan (GO:0032494) | 5.06148800 |
| 10 | macrophage activation involved in immune response (GO:0002281) | 4.96856765 |
| 11 | neutrophil activation involved in immune response (GO:0002283) | 4.80540253 |
| 12 | negative regulation of interleukin-12 production (GO:0032695) | 4.71911921 |
| 13 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.63316014 |
| 14 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.46977482 |
| 15 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.35353390 |
| 16 | negative regulation of cell killing (GO:0031342) | 4.35353390 |
| 17 | cellular extravasation (GO:0045123) | 4.32285151 |
| 18 | detection of other organism (GO:0098543) | 4.30846165 |
| 19 | detection of external biotic stimulus (GO:0098581) | 4.25471614 |
| 20 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.01120310 |
| 21 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.95595105 |
| 22 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.93194577 |
| 23 | myeloid cell activation involved in immune response (GO:0002275) | 3.92479482 |
| 24 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.86120889 |
| 25 | detection of bacterium (GO:0016045) | 3.84968774 |
| 26 | detection of biotic stimulus (GO:0009595) | 3.82752071 |
| 27 | regulation of gamma-delta T cell activation (GO:0046643) | 3.75633690 |
| 28 | neutrophil activation (GO:0042119) | 3.75019089 |
| 29 | microglial cell activation (GO:0001774) | 3.66089204 |
| 30 | granulocyte activation (GO:0036230) | 3.61884047 |
| 31 | macrophage activation (GO:0042116) | 3.58707216 |
| 32 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.57185807 |
| 33 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.57185807 |
| 34 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.56230946 |
| 35 | response to host immune response (GO:0052572) | 3.56230946 |
| 36 | leukocyte aggregation (GO:0070486) | 3.56117124 |
| 37 | response to muramyl dipeptide (GO:0032495) | 3.51627403 |
| 38 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.49877946 |
| 39 | response to host (GO:0075136) | 3.49877946 |
| 40 | response to host defenses (GO:0052200) | 3.49877946 |
| 41 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.48546343 |
| 42 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.47430619 |
| 43 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.41778869 |
| 44 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.41307749 |
| 45 | respiratory burst (GO:0045730) | 3.39201314 |
| 46 | germinal center formation (GO:0002467) | 3.39078283 |
| 47 | leukocyte degranulation (GO:0043299) | 3.35608076 |
| 48 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.30039067 |
| 49 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.26021013 |
| 50 | immunoglobulin mediated immune response (GO:0016064) | 3.25733396 |
| 51 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.23472079 |
| 52 | positive regulation of B cell differentiation (GO:0045579) | 3.22962368 |
| 53 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.21122781 |
| 54 | T-helper 1 type immune response (GO:0042088) | 3.20325155 |
| 55 | positive regulation of mast cell activation (GO:0033005) | 3.20008973 |
| 56 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.14846176 |
| 57 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.14009188 |
| 58 | defense response to protozoan (GO:0042832) | 3.13989195 |
| 59 | regulation of B cell differentiation (GO:0045577) | 3.13401867 |
| 60 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.13097241 |
| 61 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.11805076 |
| 62 | cellular response to type I interferon (GO:0071357) | 3.11538836 |
| 63 | type I interferon signaling pathway (GO:0060337) | 3.11538836 |
| 64 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.10558597 |
| 65 | response to type I interferon (GO:0034340) | 3.08766433 |
| 66 | neutrophil mediated immunity (GO:0002446) | 3.06027313 |
| 67 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.03688237 |
| 68 | negative regulation of interleukin-1 production (GO:0032692) | 3.02714243 |
| 69 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.01957763 |
| 70 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.01303597 |
| 71 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.00363563 |
| 72 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.97457288 |
| 73 | positive regulation of interferon-alpha production (GO:0032727) | 2.93752186 |
| 74 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.91968171 |
| 75 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.91924087 |
| 76 | positive regulation of mast cell degranulation (GO:0043306) | 2.91924087 |
| 77 | regulation of mast cell degranulation (GO:0043304) | 2.91663465 |
| 78 | regulation of mast cell activation (GO:0033003) | 2.91047262 |
| 79 | B cell receptor signaling pathway (GO:0050853) | 2.90276917 |
| 80 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.89913044 |
| 81 | negative regulation of T cell mediated immunity (GO:0002710) | 2.89604313 |
| 82 | positive regulation of interleukin-17 production (GO:0032740) | 2.89370151 |
| 83 | response to interleukin-15 (GO:0070672) | 2.89360807 |
| 84 | regulation of T cell tolerance induction (GO:0002664) | 2.89185546 |
| 85 | myeloid leukocyte activation (GO:0002274) | 2.88580637 |
| 86 | regulation of interferon-alpha production (GO:0032647) | 2.87582724 |
| 87 | positive regulation of interferon-beta production (GO:0032728) | 2.87000732 |
| 88 | positive regulation of type 2 immune response (GO:0002830) | 2.86919326 |
| 89 | regulation of tolerance induction (GO:0002643) | 2.86484805 |
| 90 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.84579814 |
| 91 | NIK/NF-kappaB signaling (GO:0038061) | 2.84205875 |
| 92 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.82008514 |
| 93 | mast cell activation (GO:0045576) | 2.81619414 |
| 94 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.80554530 |
| 95 | response to protozoan (GO:0001562) | 2.80370621 |
| 96 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.79444400 |
| 97 | tolerance induction (GO:0002507) | 2.78631154 |
| 98 | negative regulation of type 2 immune response (GO:0002829) | 2.76391592 |
| 99 | interferon-gamma production (GO:0032609) | 2.74632673 |
| 100 | negative regulation of interleukin-6 production (GO:0032715) | 2.74442537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.12971175 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.02059921 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.53388943 |
| 4 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.15922124 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.15737663 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.57512520 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.49714108 |
| 8 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.22685932 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.21946975 |
| 10 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.17484058 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.08412972 |
| 12 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.01965161 |
| 13 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.93600361 |
| 14 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.60959955 |
| 15 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.57527176 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.55751096 |
| 17 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.55625128 |
| 18 | SPI1_23127762_ChIP-Seq_K562_Human | 2.54419020 |
| 19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.49044490 |
| 20 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.45917599 |
| 21 | * MYB_26560356_Chip-Seq_TH2_Human | 2.44366062 |
| 22 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.29220775 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.21479390 |
| 24 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.20459811 |
| 25 | MYB_26560356_Chip-Seq_TH1_Human | 2.19760732 |
| 26 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.19630682 |
| 27 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.12497352 |
| 28 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.11387995 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.04639223 |
| 30 | MAF_26560356_Chip-Seq_TH1_Human | 2.02276093 |
| 31 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.93252075 |
| 32 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.91493995 |
| 33 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.89891131 |
| 34 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.79398109 |
| 35 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.76891802 |
| 36 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.64421245 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.63116999 |
| 38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.59625422 |
| 39 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.59092747 |
| 40 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.52572107 |
| 41 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.51712393 |
| 42 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.51708602 |
| 43 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.49262785 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43300168 |
| 45 | GATA1_22025678_ChIP-Seq_K562_Human | 1.42431460 |
| 46 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.42429384 |
| 47 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.41653865 |
| 48 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.40150275 |
| 49 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.39867315 |
| 50 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36745709 |
| 51 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.35194214 |
| 52 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.34844907 |
| 53 | * MAF_26560356_Chip-Seq_TH2_Human | 1.29849170 |
| 54 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.25896239 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25137456 |
| 56 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24186059 |
| 57 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.20655361 |
| 58 | MYC_22102868_ChIP-Seq_BL_Human | 1.20288782 |
| 59 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.18346597 |
| 60 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.17132171 |
| 61 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.13913685 |
| 62 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12019602 |
| 63 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.10739151 |
| 64 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.09370901 |
| 65 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08206912 |
| 66 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05610625 |
| 67 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.04101415 |
| 68 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.04008289 |
| 69 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.98453127 |
| 70 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95003143 |
| 71 | GATA2_19941826_ChIP-Seq_K562_Human | 0.94540495 |
| 72 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.93756686 |
| 73 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92767983 |
| 74 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92067389 |
| 75 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.91543085 |
| 76 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.91469220 |
| 77 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.91469220 |
| 78 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.91469220 |
| 79 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.90876357 |
| 80 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.89794128 |
| 81 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.89608855 |
| 82 | GATA1_19941826_ChIP-Seq_K562_Human | 0.89074187 |
| 83 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.88410895 |
| 84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.87069583 |
| 85 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.86289054 |
| 86 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84993827 |
| 87 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.84627406 |
| 88 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.83563498 |
| 89 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.83499302 |
| 90 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.82683982 |
| 91 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.82406562 |
| 92 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82334279 |
| 93 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.82132060 |
| 94 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.82132060 |
| 95 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.81189088 |
| 96 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.79541071 |
| 97 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.78331088 |
| 98 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.76112275 |
| 99 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 0.75444976 |
| 100 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.75344610 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.26324867 |
| 2 | MP0003436_decreased_susceptibility_to | 3.59987354 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.49459400 |
| 4 | MP0003303_peritoneal_inflammation | 3.43282474 |
| 5 | MP0002419_abnormal_innate_immunity | 2.90158138 |
| 6 | MP0009785_altered_susceptibility_to | 2.86107475 |
| 7 | MP0001800_abnormal_humoral_immune | 2.79416547 |
| 8 | MP0005451_abnormal_body_composition | 2.78251572 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.58950170 |
| 10 | MP0002452_abnormal_antigen_presenting | 2.48343659 |
| 11 | MP0001790_abnormal_immune_system | 2.46970230 |
| 12 | MP0005387_immune_system_phenotype | 2.46970230 |
| 13 | MP0002723_abnormal_immune_serum | 2.46556776 |
| 14 | MP0002148_abnormal_hypersensitivity_rea | 2.41773371 |
| 15 | MP0005025_abnormal_response_to | 2.40110902 |
| 16 | MP0005671_abnormal_response_to | 2.39238239 |
| 17 | MP0000685_abnormal_immune_system | 2.32977128 |
| 18 | MP0009278_abnormal_bone_marrow | 2.28440045 |
| 19 | MP0002132_abnormal_respiratory_system | 2.28034913 |
| 20 | MP0003300_gastrointestinal_ulcer | 2.22668004 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.22165278 |
| 22 | MP0001819_abnormal_immune_cell | 2.20420361 |
| 23 | MP0003191_abnormal_cellular_cholesterol | 2.19256405 |
| 24 | MP0006082_CNS_inflammation | 2.16360513 |
| 25 | MP0003828_pulmonary_edema | 2.14826978 |
| 26 | MP0008260_abnormal_autophagy | 2.01592557 |
| 27 | MP0002405_respiratory_system_inflammati | 1.99516939 |
| 28 | MP0006054_spinal_hemorrhage | 1.99195948 |
| 29 | MP0001545_abnormal_hematopoietic_system | 1.90172807 |
| 30 | MP0005397_hematopoietic_system_phenotyp | 1.90172807 |
| 31 | MP0003763_abnormal_thymus_physiology | 1.81468873 |
| 32 | MP0009764_decreased_sensitivity_to | 1.80916178 |
| 33 | MP0004947_skin_inflammation | 1.79599757 |
| 34 | MP0001853_heart_inflammation | 1.78334626 |
| 35 | MP0002398_abnormal_bone_marrow | 1.75358512 |
| 36 | MP0001533_abnormal_skeleton_physiology | 1.74130849 |
| 37 | MP0000716_abnormal_immune_system | 1.70559352 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.70137064 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.63301644 |
| 40 | MP0010155_abnormal_intestine_physiology | 1.55224891 |
| 41 | MP0003195_calcinosis | 1.51093152 |
| 42 | MP0000858_altered_metastatic_potential | 1.50740738 |
| 43 | MP0000689_abnormal_spleen_morphology | 1.49589051 |
| 44 | MP0004883_abnormal_blood_vessel | 1.46247696 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.44555438 |
| 46 | MP0002722_abnormal_immune_system | 1.43983613 |
| 47 | MP0004510_myositis | 1.42874029 |
| 48 | MP0008057_abnormal_DNA_replication | 1.39471673 |
| 49 | MP0002429_abnormal_blood_cell | 1.35873398 |
| 50 | MP0008004_abnormal_stomach_pH | 1.34848478 |
| 51 | MP0000703_abnormal_thymus_morphology | 1.31899320 |
| 52 | MP0005164_abnormal_response_to | 1.30312831 |
| 53 | MP0008469_abnormal_protein_level | 1.30117764 |
| 54 | MP0002998_abnormal_bone_remodeling | 1.28897780 |
| 55 | MP0003656_abnormal_erythrocyte_physiolo | 1.21443776 |
| 56 | MP0005310_abnormal_salivary_gland | 1.18195754 |
| 57 | MP0002166_altered_tumor_susceptibility | 1.16468351 |
| 58 | MP0003091_abnormal_cell_migration | 1.15643631 |
| 59 | MP0005058_abnormal_lysosome_morphology | 1.14503542 |
| 60 | MP0004381_abnormal_hair_follicle | 1.14124070 |
| 61 | MP0001873_stomach_inflammation | 1.13294558 |
| 62 | MP0002332_abnormal_exercise_endurance | 1.12645554 |
| 63 | MP0002277_abnormal_respiratory_mucosa | 1.10287202 |
| 64 | MP0003221_abnormal_cardiomyocyte_apopto | 1.09967135 |
| 65 | MP0005076_abnormal_cell_differentiation | 1.08855800 |
| 66 | MP0000343_altered_response_to | 1.07830087 |
| 67 | MP0002006_tumorigenesis | 1.07343311 |
| 68 | MP0002396_abnormal_hematopoietic_system | 1.06873847 |
| 69 | MP0002254_reproductive_system_inflammat | 1.05513531 |
| 70 | MP0000465_gastrointestinal_hemorrhage | 1.04147879 |
| 71 | MP0003448_altered_tumor_morphology | 1.03002297 |
| 72 | MP0004808_abnormal_hematopoietic_stem | 1.02076142 |
| 73 | MP0002138_abnormal_hepatobiliary_system | 0.97172381 |
| 74 | MP0003172_abnormal_lysosome_physiology | 0.92857484 |
| 75 | MP0001851_eye_inflammation | 0.92726821 |
| 76 | MP0000372_irregular_coat_pigmentation | 0.88481822 |
| 77 | MP0009765_abnormal_xenobiotic_induced | 0.85847065 |
| 78 | MP0009763_increased_sensitivity_to | 0.85234647 |
| 79 | MP0005410_abnormal_fertilization | 0.83654995 |
| 80 | MP0002009_preneoplasia | 0.83038276 |
| 81 | MP0000569_abnormal_digit_pigmentation | 0.81831853 |
| 82 | MP0005390_skeleton_phenotype | 0.78907339 |
| 83 | MP0003866_abnormal_defecation | 0.77808623 |
| 84 | MP0003075_altered_response_to | 0.75981660 |
| 85 | MP0005166_decreased_susceptibility_to | 0.75167290 |
| 86 | MP0001915_intracranial_hemorrhage | 0.73614593 |
| 87 | MP0000371_diluted_coat_color | 0.73169473 |
| 88 | MP0000249_abnormal_blood_vessel | 0.71986773 |
| 89 | MP0003950_abnormal_plasma_membrane | 0.70626985 |
| 90 | MP0003453_abnormal_keratinocyte_physiol | 0.70359576 |
| 91 | MP0001663_abnormal_digestive_system | 0.69889604 |
| 92 | MP0000015_abnormal_ear_pigmentation | 0.66233819 |
| 93 | MP0009115_abnormal_fat_cell | 0.63639794 |
| 94 | MP0003795_abnormal_bone_structure | 0.62458178 |
| 95 | MP0005621_abnormal_cell_physiology | 0.62410489 |
| 96 | MP0010386_abnormal_urinary_bladder | 0.61514226 |
| 97 | MP0005023_abnormal_wound_healing | 0.61006790 |
| 98 | MP0005075_abnormal_melanosome_morpholog | 0.60302245 |
| 99 | MP0002933_joint_inflammation | 0.59240494 |
| 100 | MP0000604_amyloidosis | 0.57161479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 5.85684443 |
| 2 | Recurrent abscess formation (HP:0002722) | 5.55579045 |
| 3 | Eczematoid dermatitis (HP:0000976) | 5.30940806 |
| 4 | Retrobulbar optic neuritis (HP:0100654) | 5.06133290 |
| 5 | Optic neuritis (HP:0100653) | 5.06133290 |
| 6 | Orchitis (HP:0100796) | 4.96960233 |
| 7 | Myositis (HP:0100614) | 4.92628439 |
| 8 | Abnormality of macrophages (HP:0004311) | 4.86616117 |
| 9 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.42830768 |
| 10 | Stomatitis (HP:0010280) | 4.35374390 |
| 11 | Recurrent fungal infections (HP:0002841) | 3.92472420 |
| 12 | T lymphocytopenia (HP:0005403) | 3.77872714 |
| 13 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.73926400 |
| 14 | Keratoconjunctivitis sicca (HP:0001097) | 3.64217454 |
| 15 | Abnormality of T cell number (HP:0011839) | 3.61969446 |
| 16 | Gastrointestinal infarctions (HP:0005244) | 3.59322323 |
| 17 | Panhypogammaglobulinemia (HP:0003139) | 3.56146829 |
| 18 | Recurrent skin infections (HP:0001581) | 3.50826312 |
| 19 | Mediastinal lymphadenopathy (HP:0100721) | 3.44098663 |
| 20 | Encephalitis (HP:0002383) | 3.35170613 |
| 21 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.33303052 |
| 22 | Meningitis (HP:0001287) | 3.27621105 |
| 23 | Obstructive lung disease (HP:0006536) | 3.25493830 |
| 24 | Chronic obstructive pulmonary disease (HP:0006510) | 3.25493830 |
| 25 | Keratoconjunctivitis (HP:0001096) | 3.24966081 |
| 26 | Recurrent viral infections (HP:0004429) | 3.24591454 |
| 27 | Spontaneous hematomas (HP:0007420) | 3.12596350 |
| 28 | Vasculitis (HP:0002633) | 3.07247295 |
| 29 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.97909867 |
| 30 | Recurrent cutaneous fungal infections (HP:0011370) | 2.97909867 |
| 31 | Peritonitis (HP:0002586) | 2.92510574 |
| 32 | Leukocytosis (HP:0001974) | 2.87257751 |
| 33 | Gingivitis (HP:0000230) | 2.80812486 |
| 34 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.76160146 |
| 35 | Abnormality of T cells (HP:0002843) | 2.72401640 |
| 36 | Increased IgE level (HP:0003212) | 2.65225879 |
| 37 | Pustule (HP:0200039) | 2.60504319 |
| 38 | Granulocytopenia (HP:0001913) | 2.59840366 |
| 39 | Amyloidosis (HP:0011034) | 2.57019572 |
| 40 | Eosinophilia (HP:0001880) | 2.44059925 |
| 41 | Cellulitis (HP:0100658) | 2.42310726 |
| 42 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.41622238 |
| 43 | Abnormality of the fingertips (HP:0001211) | 2.40851753 |
| 44 | Urticaria (HP:0001025) | 2.40258410 |
| 45 | Keratitis (HP:0000491) | 2.40209217 |
| 46 | Hemoptysis (HP:0002105) | 2.39425035 |
| 47 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.34671934 |
| 48 | Pulmonary infiltrates (HP:0002113) | 2.33446113 |
| 49 | Anorexia (HP:0002039) | 2.32255846 |
| 50 | Arterial thrombosis (HP:0004420) | 2.31946000 |
| 51 | Alveolar cell carcinoma (HP:0006519) | 2.31620540 |
| 52 | Osteomyelitis (HP:0002754) | 2.31020675 |
| 53 | Viral hepatitis (HP:0006562) | 2.30386537 |
| 54 | Disinhibition (HP:0000734) | 2.27115101 |
| 55 | Lymphopenia (HP:0001888) | 2.26862299 |
| 56 | Chest pain (HP:0100749) | 2.26337129 |
| 57 | Gangrene (HP:0100758) | 2.20560982 |
| 58 | Vacuolated lymphocytes (HP:0001922) | 2.18637471 |
| 59 | Fatigue (HP:0012378) | 2.17891129 |
| 60 | Premature loss of primary teeth (HP:0006323) | 2.16136814 |
| 61 | Increased IgM level (HP:0003496) | 2.15470463 |
| 62 | Subacute progressive viral hepatitis (HP:0006572) | 2.15351710 |
| 63 | Abnormality of B cell number (HP:0010975) | 2.12709882 |
| 64 | Episodic fever (HP:0001954) | 2.11808611 |
| 65 | Colitis (HP:0002583) | 2.11412674 |
| 66 | Prolonged bleeding time (HP:0003010) | 2.10765828 |
| 67 | Abnormality of T cell physiology (HP:0011840) | 2.10247835 |
| 68 | Hypochromic microcytic anemia (HP:0004840) | 2.09814048 |
| 69 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.07693799 |
| 70 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.02677054 |
| 71 | Inflammation of the large intestine (HP:0002037) | 2.02459701 |
| 72 | Hypertensive crisis (HP:0100735) | 2.01322143 |
| 73 | Abnormality of the peritoneum (HP:0002585) | 2.00545513 |
| 74 | Spondylolisthesis (HP:0003302) | 1.99460480 |
| 75 | Autoimmune hemolytic anemia (HP:0001890) | 1.96367108 |
| 76 | B lymphocytopenia (HP:0010976) | 1.95373858 |
| 77 | Autoimmune thrombocytopenia (HP:0001973) | 1.94762937 |
| 78 | Epistaxis (HP:0000421) | 1.94658043 |
| 79 | IgM deficiency (HP:0002850) | 1.94147339 |
| 80 | Amaurosis fugax (HP:0100576) | 1.90471745 |
| 81 | Petechiae (HP:0000967) | 1.89103217 |
| 82 | Abnormality of the endocardium (HP:0004306) | 1.88727024 |
| 83 | Acute hepatic failure (HP:0006554) | 1.87394720 |
| 84 | Increased serum ferritin (HP:0003281) | 1.87247231 |
| 85 | Abnormality of the thymus (HP:0000777) | 1.87131503 |
| 86 | Recurrent pneumonia (HP:0006532) | 1.86234445 |
| 87 | Gastrointestinal inflammation (HP:0004386) | 1.86081779 |
| 88 | Syringomyelia (HP:0003396) | 1.85655250 |
| 89 | Spinal cord lesions (HP:0100561) | 1.85655250 |
| 90 | Polycythemia (HP:0001901) | 1.83875386 |
| 91 | Parakeratosis (HP:0001036) | 1.82209134 |
| 92 | Glomerulopathy (HP:0100820) | 1.82057558 |
| 93 | Sepsis (HP:0100806) | 1.81966450 |
| 94 | Hematochezia (HP:0002573) | 1.81726153 |
| 95 | Polyneuropathy (HP:0001271) | 1.81391357 |
| 96 | Chronic otitis media (HP:0000389) | 1.80780256 |
| 97 | Albinism (HP:0001022) | 1.80263552 |
| 98 | Gingival bleeding (HP:0000225) | 1.79527941 |
| 99 | Acne (HP:0001061) | 1.77968647 |
| 100 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.77165157 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.77469584 |
| 2 | IRAK4 | 3.42543815 |
| 3 | TYK2 | 2.84712713 |
| 4 | BLK | 2.73000760 |
| 5 | CSK | 2.66482812 |
| 6 | MAP4K1 | 2.60577654 |
| 7 | MAP3K14 | 2.59905040 |
| 8 | EPHB1 | 2.59299086 |
| 9 | MAP2K3 | 2.09048746 |
| 10 | BMPR2 | 2.05709922 |
| 11 | IRAK1 | 2.03799871 |
| 12 | SIK3 | 1.97170600 |
| 13 | MAP3K12 | 1.96143195 |
| 14 | IKBKE | 1.90378644 |
| 15 | JAK3 | 1.84790011 |
| 16 | PRPF4B | 1.84681635 |
| 17 | AKT3 | 1.80071164 |
| 18 | PIK3CG | 1.77833742 |
| 19 | MAP3K3 | 1.68527404 |
| 20 | TAOK3 | 1.67875179 |
| 21 | BTK | 1.60815262 |
| 22 | MAP3K13 | 1.59037538 |
| 23 | IRAK3 | 1.57835194 |
| 24 | FES | 1.57262748 |
| 25 | MARK3 | 1.52628907 |
| 26 | HCK | 1.52474433 |
| 27 | ZAP70 | 1.51739109 |
| 28 | FGR | 1.48586930 |
| 29 | CDK12 | 1.47006092 |
| 30 | PDK2 | 1.46881424 |
| 31 | TGFBR2 | 1.45372206 |
| 32 | JAK1 | 1.39712633 |
| 33 | IKBKB | 1.35623139 |
| 34 | IRAK2 | 1.34925734 |
| 35 | DYRK3 | 1.32787023 |
| 36 | TXK | 1.32450707 |
| 37 | STK10 | 1.26147014 |
| 38 | ITK | 1.23191512 |
| 39 | JAK2 | 1.23153987 |
| 40 | NLK | 1.20934808 |
| 41 | YES1 | 1.19107020 |
| 42 | SYK | 1.18938881 |
| 43 | TBK1 | 1.18872172 |
| 44 | TAOK1 | 1.16376034 |
| 45 | MST4 | 1.13882251 |
| 46 | MOS | 1.13559140 |
| 47 | MAP3K1 | 1.13422173 |
| 48 | TEC | 1.11736888 |
| 49 | CSF1R | 1.09479268 |
| 50 | TNK2 | 1.06198942 |
| 51 | LYN | 1.04972574 |
| 52 | PLK4 | 1.04850365 |
| 53 | BRD4 | 1.02613105 |
| 54 | MATK | 1.01872556 |
| 55 | LCK | 1.00140870 |
| 56 | GRK6 | 0.98789875 |
| 57 | KSR2 | 0.95029372 |
| 58 | CLK1 | 0.91783010 |
| 59 | PTK2B | 0.88675764 |
| 60 | CHUK | 0.85179272 |
| 61 | ERN1 | 0.79252074 |
| 62 | TAOK2 | 0.77794016 |
| 63 | GRK7 | 0.76674888 |
| 64 | MELK | 0.75184556 |
| 65 | MAPK7 | 0.74568226 |
| 66 | KIT | 0.74495890 |
| 67 | PTK6 | 0.74433700 |
| 68 | WNK1 | 0.72036076 |
| 69 | FGFR3 | 0.71267664 |
| 70 | NME2 | 0.68914497 |
| 71 | MAP3K2 | 0.67373883 |
| 72 | PAK4 | 0.66748685 |
| 73 | ACVR1B | 0.65780577 |
| 74 | SGK2 | 0.64535874 |
| 75 | KSR1 | 0.64395405 |
| 76 | PDGFRB | 0.58736304 |
| 77 | MAP3K5 | 0.57206826 |
| 78 | SGK3 | 0.53579400 |
| 79 | STK4 | 0.53107235 |
| 80 | SIK2 | 0.52581655 |
| 81 | CDK19 | 0.51908455 |
| 82 | FGFR4 | 0.51789584 |
| 83 | TNIK | 0.50616541 |
| 84 | TRPM7 | 0.50611064 |
| 85 | PIM1 | 0.49839779 |
| 86 | PDK1 | 0.49558323 |
| 87 | DYRK1B | 0.49497494 |
| 88 | LRRK2 | 0.49495445 |
| 89 | MAP3K6 | 0.48052812 |
| 90 | EPHA3 | 0.47762473 |
| 91 | MARK2 | 0.46863806 |
| 92 | BMX | 0.44559155 |
| 93 | CDK4 | 0.42531188 |
| 94 | MAP3K11 | 0.42152177 |
| 95 | WNK3 | 0.42031082 |
| 96 | PRKCQ | 0.41536157 |
| 97 | EGFR | 0.41238254 |
| 98 | CDC42BPA | 0.40084593 |
| 99 | NEK9 | 0.39804593 |
| 100 | BRAF | 0.38773324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.75079975 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.73247222 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.37075988 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.30282722 |
| 5 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.24183612 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.21207585 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.16041625 |
| 8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.15773500 |
| 9 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.15645133 |
| 10 | Malaria_Homo sapiens_hsa05144 | 2.06465131 |
| 11 | Tuberculosis_Homo sapiens_hsa05152 | 2.05599562 |
| 12 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.05581510 |
| 13 | Legionellosis_Homo sapiens_hsa05134 | 2.02239603 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.93657491 |
| 15 | Measles_Homo sapiens_hsa05162 | 1.92267541 |
| 16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.85619710 |
| 17 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.85575657 |
| 18 | Influenza A_Homo sapiens_hsa05164 | 1.74126427 |
| 19 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.73985105 |
| 20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.72350919 |
| 21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.70705149 |
| 22 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.69342552 |
| 23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.64156399 |
| 24 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.63455442 |
| 25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.59445383 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.55924878 |
| 27 | Other glycan degradation_Homo sapiens_hsa00511 | 1.55627551 |
| 28 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.53255228 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.47303565 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.45927330 |
| 31 | Asthma_Homo sapiens_hsa05310 | 1.43981099 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.43667963 |
| 33 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.42121692 |
| 34 | Hepatitis B_Homo sapiens_hsa05161 | 1.41427560 |
| 35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.36644249 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.35659676 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.32514013 |
| 38 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.31290455 |
| 39 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.28568906 |
| 40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.26271936 |
| 41 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.22372203 |
| 42 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.17813170 |
| 43 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.16825320 |
| 44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.16697157 |
| 45 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.15821882 |
| 46 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.15425807 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.13115443 |
| 48 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.10108064 |
| 49 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.09890139 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09015120 |
| 51 | Apoptosis_Homo sapiens_hsa04210 | 1.08426897 |
| 52 | Phagosome_Homo sapiens_hsa04145 | 1.06973446 |
| 53 | Pertussis_Homo sapiens_hsa05133 | 1.03335376 |
| 54 | Hepatitis C_Homo sapiens_hsa05160 | 1.00774768 |
| 55 | Salmonella infection_Homo sapiens_hsa05132 | 0.98969085 |
| 56 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.98543150 |
| 57 | Platelet activation_Homo sapiens_hsa04611 | 0.95693379 |
| 58 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.92904614 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.92027242 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91587380 |
| 61 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.89824298 |
| 62 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.86218744 |
| 63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84608108 |
| 64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.83206293 |
| 65 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.78169378 |
| 66 | Colorectal cancer_Homo sapiens_hsa05210 | 0.77977061 |
| 67 | Lysosome_Homo sapiens_hsa04142 | 0.77045215 |
| 68 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.75957541 |
| 69 | Endometrial cancer_Homo sapiens_hsa05213 | 0.73603931 |
| 70 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71456308 |
| 71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.70817385 |
| 72 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.68179460 |
| 73 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.65658155 |
| 74 | Amoebiasis_Homo sapiens_hsa05146 | 0.63832531 |
| 75 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61319074 |
| 76 | Prostate cancer_Homo sapiens_hsa05215 | 0.60114320 |
| 77 | Bladder cancer_Homo sapiens_hsa05219 | 0.55799878 |
| 78 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.55427333 |
| 79 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.53868701 |
| 80 | Endocytosis_Homo sapiens_hsa04144 | 0.52974025 |
| 81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50302881 |
| 82 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.47020553 |
| 83 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.46965578 |
| 84 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.45492900 |
| 85 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.45133106 |
| 86 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.43102180 |
| 87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42561641 |
| 88 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41267703 |
| 89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40932171 |
| 90 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.40838425 |
| 91 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.40050325 |
| 92 | Thyroid cancer_Homo sapiens_hsa05216 | 0.39628608 |
| 93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39287059 |
| 94 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.39121338 |
| 95 | Basal transcription factors_Homo sapiens_hsa03022 | 0.37559714 |
| 96 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.36406074 |
| 97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.34250935 |
| 98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.33187743 |
| 99 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.32410651 |
| 100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.31028155 |

