Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.89070011 |
2 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.76136640 |
3 | vocalization behavior (GO:0071625) | 4.73931908 |
4 | locomotory exploration behavior (GO:0035641) | 4.73207598 |
5 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.63402323 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.56884504 |
7 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.34421787 |
8 | glutamate receptor signaling pathway (GO:0007215) | 4.20448619 |
9 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.17948038 |
10 | retinal cone cell development (GO:0046549) | 4.15482061 |
11 | synaptic vesicle exocytosis (GO:0016079) | 4.14005287 |
12 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.11843787 |
13 | glutamate secretion (GO:0014047) | 4.09881231 |
14 | synaptic vesicle maturation (GO:0016188) | 4.04535144 |
15 | neuronal action potential propagation (GO:0019227) | 4.02759891 |
16 | synaptic transmission, glutamatergic (GO:0035249) | 3.94742516 |
17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.94348490 |
18 | neuron-neuron synaptic transmission (GO:0007270) | 3.93980834 |
19 | protein localization to synapse (GO:0035418) | 3.93652241 |
20 | exploration behavior (GO:0035640) | 3.92106101 |
21 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.91524037 |
22 | neurotransmitter secretion (GO:0007269) | 3.88118817 |
23 | gamma-aminobutyric acid transport (GO:0015812) | 3.72423531 |
24 | sodium ion export (GO:0071436) | 3.70482941 |
25 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.64681143 |
26 | regulation of synaptic vesicle transport (GO:1902803) | 3.62680578 |
27 | cerebellar granule cell differentiation (GO:0021707) | 3.60821357 |
28 | neuron cell-cell adhesion (GO:0007158) | 3.58129004 |
29 | behavioral response to cocaine (GO:0048148) | 3.58127182 |
30 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.57705524 |
31 | short-term memory (GO:0007614) | 3.57374049 |
32 | long-term memory (GO:0007616) | 3.51909945 |
33 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.50868837 |
34 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.43420362 |
35 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.42184472 |
36 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.41464225 |
37 | L-amino acid import (GO:0043092) | 3.39350420 |
38 | transmission of nerve impulse (GO:0019226) | 3.37435645 |
39 | prepulse inhibition (GO:0060134) | 3.35827156 |
40 | regulation of female receptivity (GO:0045924) | 3.34110276 |
41 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.32613498 |
42 | regulation of synapse structural plasticity (GO:0051823) | 3.31920942 |
43 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.31600195 |
44 | regulation of postsynaptic membrane potential (GO:0060078) | 3.29459995 |
45 | regulation of synaptic plasticity (GO:0048167) | 3.26988087 |
46 | behavioral defense response (GO:0002209) | 3.25780855 |
47 | behavioral fear response (GO:0001662) | 3.25780855 |
48 | long-term synaptic potentiation (GO:0060291) | 3.23414976 |
49 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 3.21378653 |
50 | neurotransmitter transport (GO:0006836) | 3.19911734 |
51 | cochlea development (GO:0090102) | 3.19865668 |
52 | dendritic spine morphogenesis (GO:0060997) | 3.16412988 |
53 | synaptic transmission, dopaminergic (GO:0001963) | 3.15017153 |
54 | positive regulation of membrane potential (GO:0045838) | 3.14339564 |
55 | response to histamine (GO:0034776) | 3.14323098 |
56 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.13864969 |
57 | cellular potassium ion homeostasis (GO:0030007) | 3.13550272 |
58 | fear response (GO:0042596) | 3.12654372 |
59 | striatum development (GO:0021756) | 3.11352485 |
60 | neuron recognition (GO:0008038) | 3.10962355 |
61 | female mating behavior (GO:0060180) | 3.10864671 |
62 | cellular sodium ion homeostasis (GO:0006883) | 3.10270570 |
63 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.10080950 |
64 | cerebellar Purkinje cell layer development (GO:0021680) | 3.09855169 |
65 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.09673527 |
66 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.07570026 |
67 | proline transport (GO:0015824) | 3.07303210 |
68 | regulation of neurotransmitter levels (GO:0001505) | 3.06659357 |
69 | C4-dicarboxylate transport (GO:0015740) | 3.05874122 |
70 | synaptic vesicle endocytosis (GO:0048488) | 3.05633265 |
71 | positive regulation of synapse maturation (GO:0090129) | 3.00836379 |
72 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.00502496 |
73 | membrane depolarization during action potential (GO:0086010) | 2.99078250 |
74 | neuromuscular process controlling posture (GO:0050884) | 2.98363111 |
75 | layer formation in cerebral cortex (GO:0021819) | 2.96755669 |
76 | regulation of glutamate secretion (GO:0014048) | 2.94537926 |
77 | long term synaptic depression (GO:0060292) | 2.93769845 |
78 | amino acid import (GO:0043090) | 2.92937296 |
79 | regulation of vesicle fusion (GO:0031338) | 2.92815458 |
80 | activation of protein kinase A activity (GO:0034199) | 2.92577026 |
81 | neuromuscular process controlling balance (GO:0050885) | 2.90952750 |
82 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.90320439 |
83 | calcium ion-dependent exocytosis (GO:0017156) | 2.88440527 |
84 | mating behavior (GO:0007617) | 2.87539180 |
85 | membrane depolarization (GO:0051899) | 2.86663766 |
86 | learning (GO:0007612) | 2.84480816 |
87 | negative regulation of hormone biosynthetic process (GO:0032353) | 2.84279934 |
88 | response to amphetamine (GO:0001975) | 2.84162502 |
89 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.83393783 |
90 | regulation of DNA methylation (GO:0044030) | 2.82858006 |
91 | regulation of acrosome reaction (GO:0060046) | 2.82269698 |
92 | innervation (GO:0060384) | 2.81269047 |
93 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.81019939 |
94 | piRNA metabolic process (GO:0034587) | 2.78426064 |
95 | neuronal ion channel clustering (GO:0045161) | 2.78382742 |
96 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.75586054 |
97 | regulation of meiosis I (GO:0060631) | 2.75344729 |
98 | chemosensory behavior (GO:0007635) | 2.73856445 |
99 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.72776352 |
100 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.71973414 |
101 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.71238933 |
102 | L-phenylalanine catabolic process (GO:0006559) | 2.69621578 |
103 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.69621578 |
104 | positive regulation of neurotransmitter transport (GO:0051590) | 2.69009342 |
105 | vesicle transport along microtubule (GO:0047496) | 2.68541341 |
106 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.67715219 |
107 | dendritic spine organization (GO:0097061) | 2.66395890 |
108 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.66198389 |
109 | synaptic transmission (GO:0007268) | 2.65925174 |
110 | axonal fasciculation (GO:0007413) | 2.65728627 |
111 | regulation of dendritic spine development (GO:0060998) | 2.65094571 |
112 | presynaptic membrane assembly (GO:0097105) | 2.64420432 |
113 | potassium ion homeostasis (GO:0055075) | 2.64297435 |
114 | nephron tubule morphogenesis (GO:0072078) | 2.63884546 |
115 | nephron epithelium morphogenesis (GO:0072088) | 2.63884546 |
116 | regulation of neurotransmitter secretion (GO:0046928) | 2.63587872 |
117 | detection of calcium ion (GO:0005513) | 2.62818217 |
118 | positive regulation of dendritic spine development (GO:0060999) | 2.61271149 |
119 | social behavior (GO:0035176) | 2.60746120 |
120 | intraspecies interaction between organisms (GO:0051703) | 2.60746120 |
121 | auditory behavior (GO:0031223) | 2.60471005 |
122 | presynaptic membrane organization (GO:0097090) | 2.60207463 |
123 | righting reflex (GO:0060013) | 2.60143502 |
124 | serotonin metabolic process (GO:0042428) | 2.58983441 |
125 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.58489734 |
126 | positive regulation of meiosis (GO:0045836) | 2.55395952 |
127 | regulation of neurotransmitter transport (GO:0051588) | 2.53153179 |
128 | apical protein localization (GO:0045176) | 2.46294621 |
129 | protein localization to cilium (GO:0061512) | 2.44721387 |
130 | negative regulation of hormone metabolic process (GO:0032351) | 2.44363489 |
131 | cell communication involved in cardiac conduction (GO:0086065) | 2.43701926 |
132 | positive regulation of meiotic cell cycle (GO:0051446) | 2.39080899 |
133 | DNA methylation involved in gamete generation (GO:0043046) | 2.38625686 |
134 | primary amino compound metabolic process (GO:1901160) | 2.38088565 |
135 | acidic amino acid transport (GO:0015800) | 2.35018492 |
136 | phosphorelay signal transduction system (GO:0000160) | 2.34923272 |
137 | inner ear receptor cell development (GO:0060119) | 2.33522628 |
138 | synapsis (GO:0007129) | 2.32307044 |
139 | cell communication by electrical coupling (GO:0010644) | 2.31375212 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.68894134 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.57083908 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.44981880 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.73732997 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.71123428 |
6 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.61731164 |
7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.55011161 |
8 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.45973159 |
9 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.33007011 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.27339852 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.27339852 |
12 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.26358760 |
13 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.25923975 |
14 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.23840525 |
15 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.18396628 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.15429253 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.14525490 |
18 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.04551110 |
19 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.01832529 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.99863101 |
21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.96329587 |
22 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.95021651 |
23 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.92709846 |
24 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.92103921 |
25 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.87085052 |
26 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.86236155 |
27 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.85753924 |
28 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.79707418 |
29 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.78544246 |
30 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.76969397 |
31 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.69789235 |
32 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.69628991 |
33 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.59688826 |
34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.58816738 |
35 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.54844387 |
36 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.53523168 |
37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.52232260 |
38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.50857654 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.47401282 |
40 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.46428282 |
41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.41711061 |
42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.40351964 |
43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40037900 |
44 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39466493 |
45 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.37981310 |
46 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.37202262 |
47 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.35916456 |
48 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.34560952 |
49 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.32611812 |
50 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.32346942 |
51 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.29537923 |
52 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.29172786 |
53 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25236932 |
54 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.25069965 |
55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.24791469 |
56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24566438 |
57 | AR_25329375_ChIP-Seq_VCAP_Human | 1.22592200 |
58 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.22370545 |
59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.20593331 |
60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19417420 |
61 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.17105910 |
62 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.15563626 |
63 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.15563084 |
64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15355721 |
65 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.15344031 |
66 | VDR_22108803_ChIP-Seq_LS180_Human | 1.14902401 |
67 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.14021163 |
68 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.13694700 |
69 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12712592 |
70 | AR_19668381_ChIP-Seq_PC3_Human | 1.12446274 |
71 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.11733139 |
72 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10748102 |
73 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.10216882 |
74 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.10035485 |
75 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09846760 |
76 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.09752339 |
77 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.09013063 |
78 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.08438612 |
79 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.08133929 |
80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08133820 |
81 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.07211523 |
82 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06863803 |
83 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06535588 |
84 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06010231 |
85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05855736 |
86 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.04888204 |
87 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.04844642 |
88 | FUS_26573619_Chip-Seq_HEK293_Human | 1.04498465 |
89 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.03414141 |
90 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.03368221 |
91 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01217448 |
92 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.01217448 |
93 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.00902205 |
94 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.00764755 |
95 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.00758165 |
96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.00650386 |
97 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00127455 |
98 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99635886 |
99 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.99473728 |
100 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.99322390 |
101 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.99125424 |
102 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.99074123 |
103 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.98618996 |
104 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.97452950 |
105 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.97112305 |
106 | TP53_16413492_ChIP-PET_HCT116_Human | 0.97059658 |
107 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.95016695 |
108 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.93906616 |
109 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.93756198 |
110 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.93413795 |
111 | KDM2B_26808549_Chip-Seq_REH_Human | 0.92426487 |
112 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.92358763 |
113 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.92162442 |
114 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.92162442 |
115 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.91669633 |
116 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.91441844 |
117 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.90856137 |
118 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.89540754 |
119 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89084012 |
120 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.88624572 |
121 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.88294271 |
122 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.87852586 |
123 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.87377473 |
124 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.86987871 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.92779214 |
2 | MP0003880_abnormal_central_pattern | 4.60470295 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.87794060 |
4 | MP0002822_catalepsy | 3.68790817 |
5 | MP0009745_abnormal_behavioral_response | 3.44037185 |
6 | MP0004270_analgesia | 3.22812935 |
7 | MP0002063_abnormal_learning/memory/cond | 3.22319481 |
8 | MP0002064_seizures | 2.89023700 |
9 | MP0001968_abnormal_touch/_nociception | 2.81116175 |
10 | MP0008877_abnormal_DNA_methylation | 2.77650676 |
11 | MP0009046_muscle_twitch | 2.75383079 |
12 | MP0002572_abnormal_emotion/affect_behav | 2.69547913 |
13 | MP0002272_abnormal_nervous_system | 2.55034751 |
14 | MP0001501_abnormal_sleep_pattern | 2.54979715 |
15 | MP0001486_abnormal_startle_reflex | 2.31846071 |
16 | MP0002736_abnormal_nociception_after | 2.31677368 |
17 | MP0001440_abnormal_grooming_behavior | 2.19524283 |
18 | MP0005360_urolithiasis | 2.09333839 |
19 | MP0005423_abnormal_somatic_nervous | 2.05683520 |
20 | MP0002734_abnormal_mechanical_nocicepti | 2.04247905 |
21 | MP0002139_abnormal_hepatobiliary_system | 2.04091682 |
22 | MP0005085_abnormal_gallbladder_physiolo | 1.99659640 |
23 | MP0003329_amyloid_beta_deposits | 1.98316513 |
24 | MP0002735_abnormal_chemical_nociception | 1.91005867 |
25 | MP0009780_abnormal_chondrocyte_physiolo | 1.87627619 |
26 | MP0002909_abnormal_adrenal_gland | 1.86160238 |
27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.75811121 |
28 | MP0002067_abnormal_sensory_capabilities | 1.75718917 |
29 | MP0005410_abnormal_fertilization | 1.72706242 |
30 | MP0005365_abnormal_bile_salt | 1.70501572 |
31 | MP0002733_abnormal_thermal_nociception | 1.70168519 |
32 | MP0003123_paternal_imprinting | 1.69835552 |
33 | MP0000566_synostosis | 1.69714987 |
34 | MP0003718_maternal_effect | 1.67283535 |
35 | MP0005646_abnormal_pituitary_gland | 1.66214993 |
36 | MP0005379_endocrine/exocrine_gland_phen | 1.65066552 |
37 | MP0004924_abnormal_behavior | 1.58286532 |
38 | MP0005386_behavior/neurological_phenoty | 1.58286532 |
39 | MP0002557_abnormal_social/conspecific_i | 1.57855839 |
40 | MP0001970_abnormal_pain_threshold | 1.56156286 |
41 | MP0006276_abnormal_autonomic_nervous | 1.56152228 |
42 | MP0001984_abnormal_olfaction | 1.51294957 |
43 | MP0001529_abnormal_vocalization | 1.48446063 |
44 | MP0002184_abnormal_innervation | 1.48193514 |
45 | MP0006292_abnormal_olfactory_placode | 1.47628872 |
46 | MP0002160_abnormal_reproductive_system | 1.47172179 |
47 | MP0002837_dystrophic_cardiac_calcinosis | 1.46142097 |
48 | MP0003890_abnormal_embryonic-extraembry | 1.43873466 |
49 | MP0003879_abnormal_hair_cell | 1.43527352 |
50 | MP0008569_lethality_at_weaning | 1.42088399 |
51 | MP0004811_abnormal_neuron_physiology | 1.39826760 |
52 | MP0003121_genomic_imprinting | 1.39272284 |
53 | MP0003633_abnormal_nervous_system | 1.34206227 |
54 | MP0008872_abnormal_physiological_respon | 1.34055569 |
55 | MP0010234_abnormal_vibrissa_follicle | 1.33206653 |
56 | MP0000778_abnormal_nervous_system | 1.32718434 |
57 | MP0000955_abnormal_spinal_cord | 1.27274415 |
58 | MP0002066_abnormal_motor_capabilities/c | 1.24689302 |
59 | MP0005535_abnormal_body_temperature | 1.19231440 |
60 | MP0010329_abnormal_lipoprotein_level | 1.19031424 |
61 | MP0002089_abnormal_postnatal_growth/wei | 1.18345483 |
62 | MP0004858_abnormal_nervous_system | 1.18110603 |
63 | MP0001346_abnormal_lacrimal_gland | 1.18097295 |
64 | MP0004885_abnormal_endolymph | 1.17727530 |
65 | MP0001502_abnormal_circadian_rhythm | 1.17360112 |
66 | MP0006072_abnormal_retinal_apoptosis | 1.14255044 |
67 | MP0001905_abnormal_dopamine_level | 1.14249887 |
68 | MP0003631_nervous_system_phenotype | 1.12679069 |
69 | MP0000604_amyloidosis | 1.10891650 |
70 | MP0002882_abnormal_neuron_morphology | 1.09776752 |
71 | MP0005389_reproductive_system_phenotype | 1.09388856 |
72 | MP0004142_abnormal_muscle_tone | 1.07598305 |
73 | MP0008874_decreased_physiological_sensi | 1.06599189 |
74 | MP0002254_reproductive_system_inflammat | 1.06293210 |
75 | MP0003252_abnormal_bile_duct | 1.05960536 |
76 | MP0005248_abnormal_Harderian_gland | 1.04260911 |
77 | MP0005645_abnormal_hypothalamus_physiol | 1.03583082 |
78 | MP0001944_abnormal_pancreas_morphology | 1.03297020 |
79 | MP0002069_abnormal_eating/drinking_beha | 0.99093268 |
80 | MP0002638_abnormal_pupillary_reflex | 0.98851900 |
81 | MP0003941_abnormal_skin_development | 0.97614053 |
82 | MP0004145_abnormal_muscle_electrophysio | 0.95992510 |
83 | MP0000013_abnormal_adipose_tissue | 0.93383114 |
84 | MP0001188_hyperpigmentation | 0.91281848 |
85 | MP0002876_abnormal_thyroid_physiology | 0.89145253 |
86 | MP0002152_abnormal_brain_morphology | 0.88842172 |
87 | MP0001929_abnormal_gametogenesis | 0.88391724 |
88 | MP0003787_abnormal_imprinting | 0.87609972 |
89 | MP0005551_abnormal_eye_electrophysiolog | 0.87464453 |
90 | MP0008789_abnormal_olfactory_epithelium | 0.86826684 |
91 | MP0000579_abnormal_nail_morphology | 0.86349862 |
92 | MP0001177_atelectasis | 0.86173965 |
93 | MP0002234_abnormal_pharynx_morphology | 0.86071163 |
94 | MP0003195_calcinosis | 0.85989563 |
95 | MP0005187_abnormal_penis_morphology | 0.85796715 |
96 | MP0001299_abnormal_eye_distance/ | 0.85447273 |
97 | MP0004043_abnormal_pH_regulation | 0.85038429 |
98 | MP0003136_yellow_coat_color | 0.84935927 |
99 | MP0005332_abnormal_amino_acid | 0.84161425 |
100 | MP0004085_abnormal_heartbeat | 0.83279150 |
101 | MP0002229_neurodegeneration | 0.83140499 |
102 | MP0001485_abnormal_pinna_reflex | 0.82008603 |
103 | MP0002210_abnormal_sex_determination | 0.81235652 |
104 | MP0002161_abnormal_fertility/fecundity | 0.80599731 |
105 | MP0000427_abnormal_hair_cycle | 0.80558642 |
106 | MP0003632_abnormal_nervous_system | 0.79757851 |
107 | MP0010678_abnormal_skin_adnexa | 0.78795369 |
108 | MP0005409_darkened_coat_color | 0.78233699 |
109 | MP0005083_abnormal_biliary_tract | 0.77540455 |
110 | MP0003690_abnormal_glial_cell | 0.77418152 |
111 | MP0003075_altered_response_to | 0.75349952 |
112 | MP0002163_abnormal_gland_morphology | 0.75327507 |
113 | MP0006035_abnormal_mitochondrial_morpho | 0.75282107 |
114 | MP0008961_abnormal_basal_metabolism | 0.72620283 |
115 | MP0001963_abnormal_hearing_physiology | 0.71639946 |
116 | MP0001765_abnormal_ion_homeostasis | 0.70856444 |
117 | MP0003119_abnormal_digestive_system | 0.69801507 |
118 | MP0005394_taste/olfaction_phenotype | 0.68907750 |
119 | MP0005499_abnormal_olfactory_system | 0.68907750 |
120 | MP0000653_abnormal_sex_gland | 0.68838302 |
121 | MP0003283_abnormal_digestive_organ | 0.67340896 |
122 | MP0003698_abnormal_male_reproductive | 0.67210832 |
123 | MP0002090_abnormal_vision | 0.66864585 |
124 | MP0002118_abnormal_lipid_homeostasis | 0.64552390 |
125 | MP0003122_maternal_imprinting | 0.64304759 |
126 | MP0003868_abnormal_feces_composition | 0.59872251 |
127 | MP0005167_abnormal_blood-brain_barrier | 0.58652264 |
128 | MP0000631_abnormal_neuroendocrine_gland | 0.58245630 |
129 | MP0004742_abnormal_vestibular_system | 0.58104300 |
130 | MP0001664_abnormal_digestion | 0.58008867 |
131 | MP0010386_abnormal_urinary_bladder | 0.57951266 |
132 | MP0001666_abnormal_nutrient_absorption | 0.57888672 |
133 | MP0002078_abnormal_glucose_homeostasis | 0.54643972 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.38927000 |
2 | Myokymia (HP:0002411) | 5.91343616 |
3 | Focal seizures (HP:0007359) | 5.13810212 |
4 | Visual hallucinations (HP:0002367) | 4.49042394 |
5 | Hyperventilation (HP:0002883) | 4.21762561 |
6 | Atonic seizures (HP:0010819) | 4.17810052 |
7 | Epileptic encephalopathy (HP:0200134) | 3.97837818 |
8 | Absence seizures (HP:0002121) | 3.97485916 |
9 | Febrile seizures (HP:0002373) | 3.86299559 |
10 | Progressive cerebellar ataxia (HP:0002073) | 3.70460643 |
11 | Generalized tonic-clonic seizures (HP:0002069) | 3.62304698 |
12 | Dialeptic seizures (HP:0011146) | 3.61926877 |
13 | Action tremor (HP:0002345) | 3.60588977 |
14 | Abnormality of the lower motor neuron (HP:0002366) | 3.37422603 |
15 | Dysdiadochokinesis (HP:0002075) | 3.24762518 |
16 | Gaze-evoked nystagmus (HP:0000640) | 3.23575158 |
17 | Supernumerary spleens (HP:0009799) | 3.23563713 |
18 | Cerebral inclusion bodies (HP:0100314) | 3.22313265 |
19 | Central scotoma (HP:0000603) | 3.17117370 |
20 | Broad-based gait (HP:0002136) | 3.10222596 |
21 | Status epilepticus (HP:0002133) | 3.06897472 |
22 | Dysmetria (HP:0001310) | 3.04706201 |
23 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.03161007 |
24 | Absent/shortened dynein arms (HP:0200106) | 3.03161007 |
25 | Poor eye contact (HP:0000817) | 2.98228015 |
26 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.96114597 |
27 | Impaired social interactions (HP:0000735) | 2.95834110 |
28 | Abnormal social behavior (HP:0012433) | 2.95834110 |
29 | Anxiety (HP:0000739) | 2.93039454 |
30 | Neurofibrillary tangles (HP:0002185) | 2.92371875 |
31 | Supranuclear gaze palsy (HP:0000605) | 2.85495696 |
32 | Scanning speech (HP:0002168) | 2.83216241 |
33 | Depression (HP:0000716) | 2.80711566 |
34 | Truncal ataxia (HP:0002078) | 2.77433574 |
35 | Impaired smooth pursuit (HP:0007772) | 2.71491660 |
36 | Amblyopia (HP:0000646) | 2.70451365 |
37 | Postural instability (HP:0002172) | 2.68878451 |
38 | Epileptiform EEG discharges (HP:0011182) | 2.67943894 |
39 | Excessive salivation (HP:0003781) | 2.65126661 |
40 | Drooling (HP:0002307) | 2.65126661 |
41 | Intention tremor (HP:0002080) | 2.60887136 |
42 | Deep venous thrombosis (HP:0002625) | 2.58782144 |
43 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.57387829 |
44 | Hemiparesis (HP:0001269) | 2.54787296 |
45 | EEG with generalized epileptiform discharges (HP:0011198) | 2.51657921 |
46 | Postural tremor (HP:0002174) | 2.48900092 |
47 | Septo-optic dysplasia (HP:0100842) | 2.48312142 |
48 | Dysmetric saccades (HP:0000641) | 2.47115680 |
49 | Hypoplasia of the fovea (HP:0007750) | 2.46552554 |
50 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.46552554 |
51 | Torticollis (HP:0000473) | 2.45304332 |
52 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.44849186 |
53 | Focal dystonia (HP:0004373) | 2.38743402 |
54 | Hypsarrhythmia (HP:0002521) | 2.37096648 |
55 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.36229533 |
56 | Horizontal nystagmus (HP:0000666) | 2.36092920 |
57 | Posterior subcapsular cataract (HP:0007787) | 2.34545968 |
58 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.34406594 |
59 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.34406594 |
60 | Bradykinesia (HP:0002067) | 2.33842889 |
61 | Male infertility (HP:0003251) | 2.31681365 |
62 | Impaired vibratory sensation (HP:0002495) | 2.31539002 |
63 | Abnormal eating behavior (HP:0100738) | 2.29073016 |
64 | Prolonged partial thromboplastin time (HP:0003645) | 2.27481675 |
65 | Scotoma (HP:0000575) | 2.24974484 |
66 | Annular pancreas (HP:0001734) | 2.24005746 |
67 | Abnormality of the labia minora (HP:0012880) | 2.23222161 |
68 | Absent speech (HP:0001344) | 2.23098223 |
69 | Craniofacial dystonia (HP:0012179) | 2.21327706 |
70 | Limb dystonia (HP:0002451) | 2.19157476 |
71 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.18551120 |
72 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.18401713 |
73 | Spontaneous abortion (HP:0005268) | 2.18206568 |
74 | Spastic gait (HP:0002064) | 2.15913375 |
75 | Cholecystitis (HP:0001082) | 2.15291551 |
76 | Abnormal gallbladder physiology (HP:0012438) | 2.15291551 |
77 | Optic nerve hypoplasia (HP:0000609) | 2.13308594 |
78 | Global brain atrophy (HP:0002283) | 2.13031697 |
79 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.10400080 |
80 | Genetic anticipation (HP:0003743) | 2.05929752 |
81 | Hypobetalipoproteinemia (HP:0003563) | 2.05569515 |
82 | Blue irides (HP:0000635) | 2.04764049 |
83 | Confusion (HP:0001289) | 2.04176521 |
84 | Abnormality of the fovea (HP:0000493) | 2.04174683 |
85 | Insidious onset (HP:0003587) | 2.03475362 |
86 | Termporal pattern (HP:0011008) | 2.03475362 |
87 | Oligodactyly (hands) (HP:0001180) | 2.03465540 |
88 | Ankle clonus (HP:0011448) | 2.02903440 |
89 | Abnormality of binocular vision (HP:0011514) | 2.02404356 |
90 | Diplopia (HP:0000651) | 2.02404356 |
91 | Urinary urgency (HP:0000012) | 2.02363921 |
92 | Resting tremor (HP:0002322) | 2.01632365 |
93 | Abdominal situs inversus (HP:0003363) | 2.01548201 |
94 | Abnormality of abdominal situs (HP:0011620) | 2.01548201 |
95 | Delusions (HP:0000746) | 2.01239495 |
96 | Stereotypic behavior (HP:0000733) | 2.00163849 |
97 | Infertility (HP:0000789) | 1.99903665 |
98 | Intrahepatic cholestasis (HP:0001406) | 1.99901061 |
99 | Generalized myoclonic seizures (HP:0002123) | 1.99480252 |
100 | Abnormality of the corticospinal tract (HP:0002492) | 1.96416134 |
101 | Fair hair (HP:0002286) | 1.96065118 |
102 | Abnormal ciliary motility (HP:0012262) | 1.95817094 |
103 | Gait ataxia (HP:0002066) | 1.95738441 |
104 | Osteomalacia (HP:0002749) | 1.95229794 |
105 | Complement deficiency (HP:0004431) | 1.92306196 |
106 | Hypoglycemic coma (HP:0001325) | 1.89184707 |
107 | Enlarged penis (HP:0000040) | 1.89173635 |
108 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.86564140 |
109 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.86564140 |
110 | Urethral obstruction (HP:0000796) | 1.86487414 |
111 | Protruding tongue (HP:0010808) | 1.86409278 |
112 | Papillary thyroid carcinoma (HP:0002895) | 1.86191331 |
113 | Progressive inability to walk (HP:0002505) | 1.84833237 |
114 | Amyotrophic lateral sclerosis (HP:0007354) | 1.82269624 |
115 | Ketosis (HP:0001946) | 1.82146538 |
116 | Hemiplegia (HP:0002301) | 1.82007639 |
117 | Hydroureter (HP:0000072) | 1.81942194 |
118 | Abnormality of macular pigmentation (HP:0008002) | 1.81594934 |
119 | Psychosis (HP:0000709) | 1.81351895 |
120 | Gait imbalance (HP:0002141) | 1.80551183 |
121 | Clonus (HP:0002169) | 1.80413078 |
122 | Mutism (HP:0002300) | 1.78408640 |
123 | Neuronal loss in central nervous system (HP:0002529) | 1.78287822 |
124 | Inability to walk (HP:0002540) | 1.78163707 |
125 | Abnormality of saccadic eye movements (HP:0000570) | 1.78146735 |
126 | Hypophosphatemic rickets (HP:0004912) | 1.76927921 |
127 | Retinal atrophy (HP:0001105) | 1.76474880 |
128 | Absent septum pellucidum (HP:0001331) | 1.75362643 |
129 | Hyperlipoproteinemia (HP:0010980) | 1.73605329 |
130 | Chromsome breakage (HP:0040012) | 1.73596512 |
131 | Tetraplegia (HP:0002445) | 1.73253247 |
132 | Sensory axonal neuropathy (HP:0003390) | 1.73236360 |
133 | Pheochromocytoma (HP:0002666) | 1.71420702 |
134 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.67521936 |
135 | Rhinitis (HP:0012384) | 1.67395556 |
136 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.65971034 |
137 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.65745025 |
138 | Megaloblastic anemia (HP:0001889) | 1.64949404 |
139 | Azoospermia (HP:0000027) | 1.64780043 |
140 | Subcapsular cataract (HP:0000523) | 1.62571246 |
141 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.60919258 |
142 | Medial flaring of the eyebrow (HP:0010747) | 1.59688379 |
143 | Intestinal atresia (HP:0011100) | 1.58852621 |
144 | Genital tract atresia (HP:0001827) | 1.57938541 |
145 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.57166576 |
146 | Limb ataxia (HP:0002070) | 1.56572443 |
147 | Congenital primary aphakia (HP:0007707) | 1.54916662 |
148 | Median cleft lip (HP:0000161) | 1.54414313 |
149 | Tubulointerstitial nephritis (HP:0001970) | 1.52728534 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 5.53014808 |
2 | NTRK3 | 4.67394559 |
3 | MAP3K9 | 3.37606431 |
4 | RIPK4 | 3.01672250 |
5 | MAP3K4 | 2.96408498 |
6 | EEF2K | 2.56124645 |
7 | MAP2K4 | 2.51320922 |
8 | MINK1 | 2.38675123 |
9 | MAP2K7 | 2.31741771 |
10 | KSR2 | 2.25521699 |
11 | DAPK2 | 2.22325530 |
12 | PRKD3 | 2.14502919 |
13 | STK24 | 2.07786069 |
14 | FGFR2 | 1.92512578 |
15 | PNCK | 1.92056576 |
16 | TTK | 1.82823338 |
17 | NTRK1 | 1.77693884 |
18 | LMTK2 | 1.73534813 |
19 | PAK6 | 1.71682291 |
20 | CASK | 1.69664077 |
21 | KSR1 | 1.62888423 |
22 | STK38L | 1.61493445 |
23 | CAMKK1 | 1.60824908 |
24 | STK38 | 1.57773708 |
25 | DAPK1 | 1.54660548 |
26 | ARAF | 1.53837408 |
27 | MARK1 | 1.52834386 |
28 | MAP3K12 | 1.51941419 |
29 | PTK2B | 1.51641854 |
30 | MAP3K13 | 1.49926128 |
31 | NTRK2 | 1.49531470 |
32 | MAP3K2 | 1.40662350 |
33 | PDK4 | 1.38404459 |
34 | PDK3 | 1.38404459 |
35 | MAPKAPK3 | 1.37722526 |
36 | GRK5 | 1.37504379 |
37 | CDK5 | 1.37196820 |
38 | PRKCG | 1.33779388 |
39 | BMPR2 | 1.30358760 |
40 | PLK2 | 1.29036659 |
41 | CSNK1G1 | 1.26246222 |
42 | FES | 1.20340709 |
43 | SIK2 | 1.18195999 |
44 | PLK3 | 1.17702929 |
45 | BRD4 | 1.15634517 |
46 | MET | 1.14087768 |
47 | CAMK2A | 1.13104050 |
48 | CAMK2B | 1.10983184 |
49 | MST4 | 1.09101664 |
50 | CAMKK2 | 1.01923029 |
51 | BRSK1 | 1.00080601 |
52 | PRPF4B | 0.99717654 |
53 | STK3 | 0.96384831 |
54 | MAPKAPK5 | 0.95437898 |
55 | CSNK1G3 | 0.93800144 |
56 | TYRO3 | 0.93458375 |
57 | SGK223 | 0.92022206 |
58 | SGK494 | 0.92022206 |
59 | PINK1 | 0.89733593 |
60 | TNIK | 0.88595262 |
61 | RAF1 | 0.87473266 |
62 | WNK3 | 0.86412619 |
63 | PRKG2 | 0.85380952 |
64 | SGK2 | 0.83825919 |
65 | PDK2 | 0.83665382 |
66 | TRPM7 | 0.83522302 |
67 | RET | 0.82596172 |
68 | PDPK1 | 0.77029871 |
69 | FER | 0.74471023 |
70 | PTK2 | 0.74381124 |
71 | SGK3 | 0.74283272 |
72 | NME1 | 0.73434773 |
73 | MAP3K1 | 0.73407282 |
74 | SGK1 | 0.73378826 |
75 | CSNK1E | 0.72772205 |
76 | PDK1 | 0.72399746 |
77 | TSSK6 | 0.71703462 |
78 | CAMK1 | 0.71574399 |
79 | CSNK1A1L | 0.71487120 |
80 | UHMK1 | 0.70502702 |
81 | WNK1 | 0.68731093 |
82 | FRK | 0.68500259 |
83 | PRKCI | 0.67990855 |
84 | CDC7 | 0.67593528 |
85 | AKT3 | 0.67277989 |
86 | CAMK2G | 0.66558817 |
87 | LATS2 | 0.66209652 |
88 | LATS1 | 0.65630777 |
89 | PRKG1 | 0.64004487 |
90 | DYRK1A | 0.63642727 |
91 | FGR | 0.63332123 |
92 | CAMK2D | 0.63178861 |
93 | MAP3K7 | 0.62157770 |
94 | PLK1 | 0.62150795 |
95 | CDK18 | 0.61343091 |
96 | PRKCZ | 0.60780579 |
97 | STK11 | 0.60250834 |
98 | INSRR | 0.60151826 |
99 | CDK15 | 0.59965537 |
100 | MAP2K1 | 0.59167629 |
101 | CDK14 | 0.58846016 |
102 | PAK3 | 0.58838603 |
103 | CSNK1D | 0.58346659 |
104 | TNK2 | 0.58164560 |
105 | PRKCH | 0.57937964 |
106 | MOS | 0.57191516 |
107 | MAPK13 | 0.56488663 |
108 | FGFR1 | 0.55294357 |
109 | PHKG1 | 0.54672283 |
110 | ZAK | 0.54495821 |
111 | WNK4 | 0.53173850 |
112 | CSNK1G2 | 0.52876057 |
113 | CAMK1G | 0.52333993 |
114 | BCR | 0.51920593 |
115 | PRKCE | 0.51876539 |
116 | BRAF | 0.51415523 |
117 | FGFR3 | 0.50312160 |
118 | CDK11A | 0.49170403 |
119 | RPS6KA3 | 0.49082221 |
120 | MARK2 | 0.47815413 |
121 | EIF2AK3 | 0.47728845 |
122 | STK39 | 0.47209923 |
123 | YES1 | 0.46851366 |
124 | RPS6KB1 | 0.46439595 |
125 | TAF1 | 0.44504960 |
126 | RIPK1 | 0.43966428 |
127 | MAPK10 | 0.43880363 |
128 | CAMK4 | 0.43747039 |
129 | NEK6 | 0.42731150 |
130 | MAP3K6 | 0.41351311 |
131 | OXSR1 | 0.38987307 |
132 | GRK7 | 0.38334394 |
133 | CDK19 | 0.37588029 |
134 | PRKACA | 0.37552915 |
135 | PRKCB | 0.35949945 |
136 | GRK6 | 0.35690593 |
137 | FYN | 0.35444565 |
138 | PHKG2 | 0.33259961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.67952879 |
2 | Long-term potentiation_Homo sapiens_hsa04720 | 2.65736106 |
3 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.62486317 |
4 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.58883596 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.50023434 |
6 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.48083252 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.43860373 |
8 | Circadian entrainment_Homo sapiens_hsa04713 | 2.41416055 |
9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.41258727 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.36224612 |
11 | Morphine addiction_Homo sapiens_hsa05032 | 2.20431865 |
12 | Olfactory transduction_Homo sapiens_hsa04740 | 2.11618809 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 1.97403383 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.96041617 |
15 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.91104008 |
16 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.83973491 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 1.82368249 |
18 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.80030651 |
19 | Taste transduction_Homo sapiens_hsa04742 | 1.72923575 |
20 | Renin secretion_Homo sapiens_hsa04924 | 1.70701057 |
21 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.69170403 |
22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.67499507 |
23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.61678087 |
24 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.53212132 |
25 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.52337088 |
26 | Long-term depression_Homo sapiens_hsa04730 | 1.50652320 |
27 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.49379446 |
28 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.48088023 |
29 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.43396932 |
30 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.36258107 |
31 | Bile secretion_Homo sapiens_hsa04976 | 1.31662218 |
32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.30641599 |
33 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27041848 |
34 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.26043811 |
35 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.21103978 |
36 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.13246546 |
37 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.11036686 |
38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.11036062 |
39 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.10524863 |
40 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.05349442 |
41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01729237 |
42 | Gap junction_Homo sapiens_hsa04540 | 1.00130754 |
43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.94430706 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.94260965 |
45 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.93890335 |
46 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.93519323 |
47 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.92588963 |
48 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.92575694 |
49 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.91866274 |
50 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.91663427 |
51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91390738 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.87504218 |
53 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.83261770 |
54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.80727620 |
55 | Basal transcription factors_Homo sapiens_hsa03022 | 0.80567125 |
56 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.80152518 |
57 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.77766933 |
58 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.77487112 |
59 | Melanogenesis_Homo sapiens_hsa04916 | 0.76744004 |
60 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.76377455 |
61 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.75397243 |
62 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.73950212 |
63 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.73431085 |
64 | Mismatch repair_Homo sapiens_hsa03430 | 0.73271598 |
65 | Tight junction_Homo sapiens_hsa04530 | 0.71294720 |
66 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69353248 |
67 | Protein export_Homo sapiens_hsa03060 | 0.69275321 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67689122 |
69 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.65857942 |
70 | Glioma_Homo sapiens_hsa05214 | 0.65841960 |
71 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.65169870 |
72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.64393815 |
73 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.63759506 |
74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62992894 |
75 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.62761642 |
76 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.61746896 |
77 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.61689430 |
78 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.59952878 |
79 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58498235 |
80 | Axon guidance_Homo sapiens_hsa04360 | 0.57269203 |
81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57191982 |
82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56824471 |
83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.56076269 |
84 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55178556 |
85 | Prion diseases_Homo sapiens_hsa05020 | 0.54320433 |
86 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.54058075 |
87 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.52712975 |
88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51474003 |
89 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50820270 |
90 | Cell cycle_Homo sapiens_hsa04110 | 0.50440123 |
91 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.50077346 |
92 | Circadian rhythm_Homo sapiens_hsa04710 | 0.49469887 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48612383 |
94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48490172 |
95 | Phototransduction_Homo sapiens_hsa04744 | 0.48334877 |
96 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.47722143 |
97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.47225225 |
98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46287716 |
99 | Huntingtons disease_Homo sapiens_hsa05016 | 0.46263432 |
100 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.44774188 |
101 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44312644 |
102 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44292297 |
103 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44138338 |
104 | Histidine metabolism_Homo sapiens_hsa00340 | 0.44034224 |
105 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42347087 |
106 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.42311009 |
107 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.41313549 |
108 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.40778227 |
109 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.40698748 |
110 | Mineral absorption_Homo sapiens_hsa04978 | 0.40630903 |
111 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39374622 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.39309211 |
113 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.39239535 |
114 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.37960651 |
115 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37811815 |
116 | Alzheimers disease_Homo sapiens_hsa05010 | 0.37479693 |
117 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.37469039 |
118 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.37307714 |
119 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.37172697 |
120 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36689660 |
121 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35417650 |
122 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.35057178 |
123 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.34993995 |
124 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34781367 |
125 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34762193 |
126 | ABC transporters_Homo sapiens_hsa02010 | 0.34123643 |
127 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.33009846 |
128 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.32614454 |
129 | Peroxisome_Homo sapiens_hsa04146 | 0.31041020 |
130 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.29966709 |