PRADC1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pseudouridine synthesis (GO:0001522)8.58466977
2oligosaccharide catabolic process (GO:0009313)7.64631685
3negative regulation of T cell receptor signaling pathway (GO:0050860)6.75784513
4SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146)6.16191293
5negative regulation of smooth muscle cell differentiation (GO:0051151)5.94032673
6negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)5.78602805
7chemosensory behavior (GO:0007635)5.73521708
8negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)5.45424214
9cellular response to ATP (GO:0071318)5.27306240
10regulation of mitotic spindle organization (GO:0060236)5.18491470
11outer ear morphogenesis (GO:0042473)5.12951893
12DNA deamination (GO:0045006)5.02146432
13negative regulation of DNA-templated transcription, elongation (GO:0032785)4.95614757
14post-embryonic morphogenesis (GO:0009886)4.92552066
15NIK/NF-kappaB signaling (GO:0038061)4.81650120
16negative regulation of cell aging (GO:0090344)4.77136597
17positive regulation of microtubule polymerization (GO:0031116)4.72288673
18regulation of T cell receptor signaling pathway (GO:0050856)4.70775431
19positive regulation of B cell differentiation (GO:0045579)4.65144959
20regulation of skeletal muscle contraction (GO:0014819)4.38203135
21cell morphogenesis involved in neuron differentiation (GO:0048667)4.37926409
22detection of light stimulus involved in visual perception (GO:0050908)4.07669562
23detection of light stimulus involved in sensory perception (GO:0050962)4.07669562
24negative regulation of B cell proliferation (GO:0030889)4.04082237
25activated T cell proliferation (GO:0050798)4.00869646
26positive regulation of gamma-delta T cell activation (GO:0046645)3.91952435
27negative regulation of Ras GTPase activity (GO:0034261)3.91590405
28branching involved in prostate gland morphogenesis (GO:0060442)3.81815736
29meiotic chromosome segregation (GO:0045132)3.78772845
30positive regulation of megakaryocyte differentiation (GO:0045654)3.76879989
31regulation of RIG-I signaling pathway (GO:0039535)3.71320917
32base-excision repair, AP site formation (GO:0006285)3.70695054
33positive regulation of granulocyte differentiation (GO:0030854)3.67498528
34trophectodermal cell differentiation (GO:0001829)3.65982657
35cellular response to dsRNA (GO:0071359)3.63518268
36microtubule depolymerization (GO:0007019)3.63318598
37negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)3.61384287
38regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.57680134
39regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.55917026
40positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.51251041
41histone H2A monoubiquitination (GO:0035518)3.46841396
42peristalsis (GO:0030432)3.46752930
43purinergic nucleotide receptor signaling pathway (GO:0035590)3.44906838
44negative regulation of interleukin-17 production (GO:0032700)3.41477046
45regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.41082059
46melanin biosynthetic process (GO:0042438)3.40069365
47peptidyl-glutamic acid carboxylation (GO:0017187)3.39814612
48protein carboxylation (GO:0018214)3.39814612
49negative regulation of DNA repair (GO:0045738)3.38381916
50GDP-mannose metabolic process (GO:0019673)3.34045780
51cell wall macromolecule catabolic process (GO:0016998)3.33747368
52protoporphyrinogen IX biosynthetic process (GO:0006782)3.32227110
53mitotic cell cycle arrest (GO:0071850)3.30609977
54Arp2/3 complex-mediated actin nucleation (GO:0034314)3.29349574
55ribosomal small subunit assembly (GO:0000028)3.29331916
56cytokine biosynthetic process (GO:0042089)3.28384757
57DNA double-strand break processing (GO:0000729)3.27739932
58melanin metabolic process (GO:0006582)3.27528095
59DNA catabolic process, exonucleolytic (GO:0000738)3.27261146
60phosphatidylglycerol biosynthetic process (GO:0006655)3.26000846
61phenylpropanoid metabolic process (GO:0009698)3.23784392
62regulation of gamma-delta T cell differentiation (GO:0045586)3.22896121
63positive regulation of actin cytoskeleton reorganization (GO:2000251)3.19617396
64positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.16429120
65regulation of B cell differentiation (GO:0045577)3.16068874
66G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.13895325
67transepithelial transport (GO:0070633)3.13367665
68regulation of spindle organization (GO:0090224)3.13119700
69mitotic metaphase plate congression (GO:0007080)3.10936062
70regulation of DNA damage checkpoint (GO:2000001)3.08924261
71response to peptidoglycan (GO:0032494)3.08380795
72positive regulation of histone methylation (GO:0031062)3.07836367
73regulation of protein polyubiquitination (GO:1902914)2.99395340
74regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.97972685
75negative regulation of bone mineralization (GO:0030502)2.97366999
76synaptonemal complex assembly (GO:0007130)2.97265018
77DNA strand renaturation (GO:0000733)2.96090850
78mitotic chromosome condensation (GO:0007076)2.95899005
79ganglioside metabolic process (GO:0001573)2.95305417
80negative regulation of erythrocyte differentiation (GO:0045647)2.93878644
81sensory perception of smell (GO:0007608)2.92047520
82DNA dealkylation (GO:0035510)2.91185469
83fibroblast migration (GO:0010761)2.88736348
84calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.88544797
85purine ribonucleotide transport (GO:0015868)2.87183231
86iron-sulfur cluster assembly (GO:0016226)2.80480346
87metallo-sulfur cluster assembly (GO:0031163)2.80480346
88granulocyte differentiation (GO:0030851)2.79533983
89regulation of defense response to virus by host (GO:0050691)2.78657252
90actin nucleation (GO:0045010)2.78640872
91cytidine metabolic process (GO:0046087)2.76766684
92cytidine catabolic process (GO:0006216)2.76766684
93cytidine deamination (GO:0009972)2.76766684
94regulation of gamma-delta T cell activation (GO:0046643)2.74916792
95positive regulation of TOR signaling (GO:0032008)2.74462262
96cytokine metabolic process (GO:0042107)2.73231868
97cell wall macromolecule metabolic process (GO:0044036)2.71800381
98exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.71777882
99positive regulation of heat generation (GO:0031652)2.65025518
100regulation of cytokine production involved in inflammatory response (GO:1900015)2.64228596

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse6.55893945
2BP1_19119308_ChIP-ChIP_Hs578T_Human6.30118134
3STAT6_21828071_ChIP-Seq_BEAS2B_Human5.10487932
4VDR_21846776_ChIP-Seq_THP-1_Human3.88769857
5SCL_19346495_ChIP-Seq_HPC-7_Human3.22113598
6CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.97911115
7BCL6_27268052_Chip-Seq_Bcells_Human2.34287438
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.23216989
9STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.19882614
10YY1_22570637_ChIP-Seq_MALME-3M_Human2.13421663
11P68_20966046_ChIP-Seq_HELA_Human2.09727172
12MYC_22102868_ChIP-Seq_BL_Human2.09702972
13TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08061499
14VDR_24763502_ChIP-Seq_THP-1_Human2.05564473
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.95945703
16MAF_26560356_Chip-Seq_TH2_Human1.94853000
17E2F1_20622854_ChIP-Seq_HELA_Human1.92057622
18NOTCH1_21737748_ChIP-Seq_TLL_Human1.89867744
19FOXM1_23109430_ChIP-Seq_U2OS_Human1.89258625
20MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.87601612
21XRN2_22483619_ChIP-Seq_HELA_Human1.82111705
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82004571
23EWS_26573619_Chip-Seq_HEK293_Human1.81042452
24BCOR_27268052_Chip-Seq_Bcells_Human1.79547601
25PHF8_20622854_ChIP-Seq_HELA_Human1.74131469
26MAF_26560356_Chip-Seq_TH1_Human1.72150307
27IGF1R_20145208_ChIP-Seq_DFB_Human1.69776523
28KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.66690471
29ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.63414507
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.59945130
31CTCF_27219007_Chip-Seq_ERYTHROID_Human1.58509619
32P300_27268052_Chip-Seq_Bcells_Human1.57716358
33CTCF_20526341_ChIP-Seq_ESCs_Human1.53534946
34CTCF_27219007_Chip-Seq_Bcells_Human1.52570452
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50848101
36SMC4_20622854_ChIP-Seq_HELA_Human1.47007336
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.46934184
38RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44564025
39PU.1_20513432_ChIP-Seq_Bcells_Mouse1.41543499
40LXR_22292898_ChIP-Seq_THP-1_Human1.41010806
41SA1_27219007_Chip-Seq_ERYTHROID_Human1.40804066
42SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.39551571
43RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.33725077
44EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.33309777
45MYC_19829295_ChIP-Seq_ESCs_Human1.32747904
46CTCF_21964334_Chip-Seq_Bcells_Human1.30815108
47CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.29090348
48ETS1_21867929_ChIP-Seq_TH2_Mouse1.27920516
49KDM2B_26808549_Chip-Seq_SUP-B15_Human1.27840350
50MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.27757845
51AR_21572438_ChIP-Seq_LNCaP_Human1.27515722
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27445658
53UTX_26944678_Chip-Seq_JUKART_Human1.26928919
54MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.25888638
55ELF1_20517297_ChIP-Seq_JURKAT_Human1.24784823
56GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.24750261
57SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.23714451
58DCP1A_22483619_ChIP-Seq_HELA_Human1.21836296
59IRF8_21731497_ChIP-ChIP_J774_Mouse1.21574102
60EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20285460
61DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.19848152
62NANOG_20526341_ChIP-Seq_ESCs_Human1.18680313
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.16786960
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.16389273
65BRD4_27068464_Chip-Seq_AML-cells_Mouse1.15949291
66PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.14678020
67LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.11721719
68E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09850234
69SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09249003
70DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.08789081
71EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.08785188
72VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.08319168
73TET1_21451524_ChIP-Seq_MESCs_Mouse1.08167655
74SPI1_20517297_ChIP-Seq_HL60_Human1.05691298
75RAC3_21632823_ChIP-Seq_H3396_Human1.05384613
76OCT4_19829295_ChIP-Seq_ESCs_Human1.03311151
77NCOR1_26117541_ChIP-Seq_K562_Human1.03105710
78RARB_24833708_ChIP-Seq_LIVER_Mouse1.02268090
79GATA1_19941826_ChIP-Seq_K562_Human1.01353368
80EGR1_23403033_ChIP-Seq_LIVER_Mouse0.98912643
81CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98846825
82SA1_27219007_Chip-Seq_Bcells_Human0.97575298
83TCF7_22412390_ChIP-Seq_EML_Mouse0.97042195
84SPI1_23547873_ChIP-Seq_NB4_Human0.96770671
85MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.96604254
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.96322488
87PKCTHETA_26484144_Chip-Seq_BREAST_Human0.96112522
88MYB_21317192_ChIP-Seq_ERMYB_Mouse0.96077217
89FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.94920069
90VDR_23849224_ChIP-Seq_CD4+_Human0.94588028
91CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.94074741
92P63_26484246_Chip-Seq_KERATINOCYTES_Human0.93985338
93CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.93282176
94CREB1_26743006_Chip-Seq_LNCaP_Human0.92917472
95CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92834991
96P53_21459846_ChIP-Seq_SAOS-2_Human0.92669050
97RXRA_24833708_ChIP-Seq_LIVER_Mouse0.91646409
98GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90933665
99RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90645958
100CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90195277

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.66932391
2MP0005451_abnormal_body_composition4.79070740
3MP0005174_abnormal_tail_pigmentation4.59989112
4MP0005083_abnormal_biliary_tract3.79046369
5MP0003329_amyloid_beta_deposits3.66662373
6MP0003136_yellow_coat_color3.62382389
7MP0005171_absent_coat_pigmentation3.52358021
8MP0000604_amyloidosis2.68947525
9MP0003567_abnormal_fetal_cardiomyocyte2.52426535
10MP0001986_abnormal_taste_sensitivity2.38416940
11MP0003011_delayed_dark_adaptation2.38094765
12MP0005397_hematopoietic_system_phenotyp2.32264704
13MP0001545_abnormal_hematopoietic_system2.32264704
14MP0000015_abnormal_ear_pigmentation2.20605811
15MP0008875_abnormal_xenobiotic_pharmacok2.18258647
16MP0000566_synostosis2.09931302
17MP0000685_abnormal_immune_system1.99729792
18MP0006072_abnormal_retinal_apoptosis1.97367924
19MP0009046_muscle_twitch1.93154755
20MP0003045_fibrosis1.89491526
21MP0001873_stomach_inflammation1.74186386
22MP0005671_abnormal_response_to1.65946270
23MP0005423_abnormal_somatic_nervous1.63138984
24MP0005253_abnormal_eye_physiology1.62830972
25MP0009278_abnormal_bone_marrow1.48647377
26MP0002638_abnormal_pupillary_reflex1.44322557
27MP0002398_abnormal_bone_marrow1.31476673
28MP0000689_abnormal_spleen_morphology1.30865001
29MP0003763_abnormal_thymus_physiology1.25645848
30MP0003693_abnormal_embryo_hatching1.23764708
31MP0001790_abnormal_immune_system1.21835656
32MP0005387_immune_system_phenotype1.21835656
33MP0005464_abnormal_platelet_physiology1.20920736
34MP0002160_abnormal_reproductive_system1.20293137
35MP0005410_abnormal_fertilization1.19853524
36MP0005084_abnormal_gallbladder_morpholo1.19354129
37MP0002722_abnormal_immune_system1.18672138
38MP0005332_abnormal_amino_acid1.17337523
39MP0002254_reproductive_system_inflammat1.13928552
40MP0002277_abnormal_respiratory_mucosa1.13050869
41MP0005058_abnormal_lysosome_morphology1.11218930
42MP0001800_abnormal_humoral_immune1.10970501
43MP0002148_abnormal_hypersensitivity_rea1.10884870
44MP0004381_abnormal_hair_follicle1.07857723
45MP0001968_abnormal_touch/_nociception1.06562245
46MP0003137_abnormal_impulse_conducting1.06499956
47MP0005551_abnormal_eye_electrophysiolog1.05883405
48MP0000716_abnormal_immune_system1.03639730
49MP0003632_abnormal_nervous_system1.01493031
50MP0001765_abnormal_ion_homeostasis0.99009839
51MP0002420_abnormal_adaptive_immunity0.97793850
52MP0002452_abnormal_antigen_presenting0.96401780
53MP0001485_abnormal_pinna_reflex0.94709748
54MP0001819_abnormal_immune_cell0.94466517
55MP0003718_maternal_effect0.93247589
56MP0005000_abnormal_immune_tolerance0.92734713
57MP0002723_abnormal_immune_serum0.92384718
58MP0001756_abnormal_urination0.91481597
59MP0008789_abnormal_olfactory_epithelium0.90737762
60MP0002405_respiratory_system_inflammati0.89797156
61MP0001666_abnormal_nutrient_absorption0.89076814
62MP0002429_abnormal_blood_cell0.88672518
63MP0005025_abnormal_response_to0.88568851
64MP0000703_abnormal_thymus_morphology0.88055763
65MP0001502_abnormal_circadian_rhythm0.86805038
66MP0005499_abnormal_olfactory_system0.85929831
67MP0005394_taste/olfaction_phenotype0.85929831
68MP0001963_abnormal_hearing_physiology0.85872668
69MP0001853_heart_inflammation0.85659403
70MP0003806_abnormal_nucleotide_metabolis0.84024767
71MP0009333_abnormal_splenocyte_physiolog0.83874909
72MP0002095_abnormal_skin_pigmentation0.83161875
73MP0001905_abnormal_dopamine_level0.82899320
74MP0000516_abnormal_urinary_system0.82473732
75MP0005367_renal/urinary_system_phenotyp0.82473732
76MP0002933_joint_inflammation0.80344276
77MP0009643_abnormal_urine_homeostasis0.79581202
78MP0000049_abnormal_middle_ear0.78097048
79MP0000751_myopathy0.77276852
80MP0003943_abnormal_hepatobiliary_system0.76368301
81MP0002138_abnormal_hepatobiliary_system0.74943219
82MP0003866_abnormal_defecation0.74866483
83MP0001919_abnormal_reproductive_system0.74827003
84MP0004808_abnormal_hematopoietic_stem0.74159396
85MP0003656_abnormal_erythrocyte_physiolo0.72366073
86MP0002229_neurodegeneration0.70313612
87MP0000371_diluted_coat_color0.69894516
88MP0002106_abnormal_muscle_physiology0.69441277
89MP0001501_abnormal_sleep_pattern0.68612258
90MP0001929_abnormal_gametogenesis0.67292524
91MP0006036_abnormal_mitochondrial_physio0.66999671
92MP0008569_lethality_at_weaning0.66903508
93MP0005389_reproductive_system_phenotype0.64565177
94MP0008469_abnormal_protein_level0.64017667
95MP0000013_abnormal_adipose_tissue0.63229978
96MP0005395_other_phenotype0.62991534
97MP0005584_abnormal_enzyme/coenzyme_acti0.60128372
98MP0008872_abnormal_physiological_respon0.58153367
99MP0000026_abnormal_inner_ear0.57059428
100MP0002067_abnormal_sensory_capabilities0.56820710

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.90691462
2Congenital stationary night blindness (HP:0007642)5.72752944
3Duplicated collecting system (HP:0000081)5.50166799
4Abnormal biliary tract physiology (HP:0012439)5.42773315
5Bile duct proliferation (HP:0001408)5.42773315
6Abnormality of the renal collecting system (HP:0004742)5.31207991
7Chromosomal breakage induced by crosslinking agents (HP:0003221)4.86529550
8Vacuolated lymphocytes (HP:0001922)4.70638514
9Global brain atrophy (HP:0002283)4.63651114
10Abnormality of pyrimidine metabolism (HP:0004353)4.07686422
11Chromsome breakage (HP:0040012)4.01742918
12Abnormality of DNA repair (HP:0003254)3.95280086
13Abnormality of midbrain morphology (HP:0002418)3.82377242
14Molar tooth sign on MRI (HP:0002419)3.82377242
15Bifid tongue (HP:0010297)3.76643053
16Optic nerve coloboma (HP:0000588)3.72907061
17Impaired smooth pursuit (HP:0007772)3.62823631
18Hypercortisolism (HP:0001578)3.61766599
19Absent thumb (HP:0009777)3.51764122
20Increased neuronal autofluorescent lipopigment (HP:0002074)3.24139609
21Ureteral duplication (HP:0000073)3.13845415
22Failure to thrive in infancy (HP:0001531)3.08297520
23Attenuation of retinal blood vessels (HP:0007843)3.07032144
24Testicular atrophy (HP:0000029)3.01568719
25Limb dystonia (HP:0002451)2.93280109
26Recurrent cutaneous fungal infections (HP:0011370)2.84402181
27Chronic mucocutaneous candidiasis (HP:0002728)2.84402181
28Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.83895976
29Clubbing of toes (HP:0100760)2.79662123
30Prolonged partial thromboplastin time (HP:0003645)2.78684436
31Ectopic kidney (HP:0000086)2.78282968
32Increased cerebral lipofuscin (HP:0011813)2.77814334
33Lipid accumulation in hepatocytes (HP:0006561)2.73659074
34Annular pancreas (HP:0001734)2.69682386
35Aplasia/Hypoplasia of the spleen (HP:0010451)2.69643398
36Asplenia (HP:0001746)2.64296095
37Truncal obesity (HP:0001956)2.62077785
38Abnormal pupillary function (HP:0007686)2.61279721
39True hermaphroditism (HP:0010459)2.61204089
40Abnormality of the intrinsic pathway (HP:0010989)2.60167074
41Absent radius (HP:0003974)2.59318224
42Joint hemorrhage (HP:0005261)2.51656451
43Abnormal delayed hypersensitivity skin test (HP:0002963)2.50923160
44Dyschromatopsia (HP:0007641)2.50811006
45Increased hepatocellular lipid droplets (HP:0006565)2.49873071
46Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.49213631
47Aplasia involving forearm bones (HP:0009822)2.46136467
48Absent forearm bone (HP:0003953)2.46136467
49Increased muscle lipid content (HP:0009058)2.42870937
50Aplasia/Hypoplasia of the uvula (HP:0010293)2.42459146
51Mesangial abnormality (HP:0001966)2.41568842
52Hemiparesis (HP:0001269)2.39747249
53Neurofibrillary tangles (HP:0002185)2.37035028
54Increased intramyocellular lipid droplets (HP:0012240)2.36233148
55Duplication of thumb phalanx (HP:0009942)2.33663832
56Pancreatic fibrosis (HP:0100732)2.33238949
57Abnormality of reticulocytes (HP:0004312)2.32257453
58Rib fusion (HP:0000902)2.32121325
59Epiphyseal dysplasia (HP:0002656)2.30575242
60Meckel diverticulum (HP:0002245)2.29379129
61Panhypogammaglobulinemia (HP:0003139)2.28745673
62Nephronophthisis (HP:0000090)2.27498920
63Diplopia (HP:0000651)2.24487098
64Abnormality of binocular vision (HP:0011514)2.24487098
65Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.23976404
66Confusion (HP:0001289)2.23009258
67Abnormality of ocular smooth pursuit (HP:0000617)2.22905525
68Pancreatic cysts (HP:0001737)2.21686211
69Decreased electroretinogram (ERG) amplitude (HP:0000654)2.20635570
70Pallor (HP:0000980)2.11321342
71Rectal fistula (HP:0100590)2.11015405
72Rectovaginal fistula (HP:0000143)2.11015405
73Tachypnea (HP:0002789)2.10965238
74Facial diplegia (HP:0001349)2.10830895
75Abnormality of the ileum (HP:0001549)2.08247072
76Premature graying of hair (HP:0002216)2.06964536
77Renal Fanconi syndrome (HP:0001994)2.05199904
78Myelodysplasia (HP:0002863)2.04663220
79Abnormal number of erythroid precursors (HP:0012131)2.03693258
80Hypoplasia of the brainstem (HP:0002365)2.03053603
81Aplasia/Hypoplasia of the brainstem (HP:0007362)2.03053603
82Gastrointestinal inflammation (HP:0004386)2.02600284
83Inflammation of the large intestine (HP:0002037)2.02351343
84Abnormality of the preputium (HP:0100587)2.00917986
85Severe global developmental delay (HP:0011344)2.00184420
86Exercise-induced myalgia (HP:0003738)1.98858485
87Facial hemangioma (HP:0000329)1.96139779
88Abnormality of the common coagulation pathway (HP:0010990)1.93541031
89Poikiloderma (HP:0001029)1.90532290
90Recurrent fungal infections (HP:0002841)1.86903709
91Abnormality of cells of the erythroid lineage (HP:0012130)1.86877299
92Decreased central vision (HP:0007663)1.86508089
93Aplasia of the musculature (HP:0100854)1.84177077
94Intestinal fistula (HP:0100819)1.83515487
95Febrile seizures (HP:0002373)1.82811653
96Dysautonomia (HP:0002459)1.81785769
97Esophageal neoplasm (HP:0100751)1.81727918
98Neoplasm of head and neck (HP:0012288)1.81727918
99Bradykinesia (HP:0002067)1.81622634
100Hemorrhage of the eye (HP:0011885)1.80391919

Predicted kinase interactions (KEA)

RankGene SetZ-score
1GRK16.52852593
2ADRBK24.66406163
3MAPK154.44941718
4TESK24.31441977
5FGFR33.10594567
6BUB13.09439244
7PIM23.01645142
8TXK2.71789380
9NME22.58000637
10TBK12.23572747
11DDR22.03965520
12CCNB11.85107426
13DYRK1A1.71222923
14SCYL21.55127901
15TAOK11.51422793
16ADRBK11.49730517
17MAP3K11.47256891
18MAP3K141.45983506
19RAF11.44253807
20IKBKE1.32557558
21MAP4K21.29630033
22BLK1.29338091
23MAP4K11.29204235
24NTRK31.23775004
25MAPK121.21674836
26MAP3K41.21175674
27MUSK1.19995780
28VRK11.10739087
29GRK61.10291225
30SYK1.04294590
31JAK30.97336464
32IKBKB0.91118913
33DAPK20.89492468
34PKN20.89322826
35IRAK10.85478549
36RPS6KA60.84941861
37RPS6KC10.84938053
38RPS6KL10.84938053
39PIM10.84130794
40TLK10.82889471
41WNK40.82737909
42NEK20.82519728
43IRAK30.80834886
44SIK20.77985551
45CDK30.77644189
46DYRK20.74733788
47RPS6KB20.73918522
48FLT30.70687059
49DYRK1B0.68584839
50CDK40.67268532
51PTK2B0.65798345
52LATS10.65605527
53UHMK10.65503265
54AURKA0.63255824
55MAP2K20.61933219
56NUAK10.59703052
57CSK0.58679392
58PRKD20.58477780
59ZAK0.56163042
60RPS6KA50.55539637
61MAP3K20.54861368
62PBK0.53494658
63RET0.52849030
64LYN0.50555963
65TAOK20.49202775
66MAPK30.48862855
67MARK30.48176631
68CHEK20.45365474
69FES0.45196326
70RPS6KA20.43743194
71ERN10.43321237
72MAP2K30.41304241
73PAK10.41152701
74MAPK70.40938108
75TAOK30.40840223
76CDK50.40567927
77TRIM280.39928837
78IRAK20.39028285
79TRPM70.38192643
80MAPK110.35422710
81AKT20.33988043
82PRKCQ0.33749487
83LCK0.33737649
84GRK70.31149036
85ATR0.30858435
86JAK20.30624856
87GRK50.30421266
88INSR0.28044736
89STK380.26449604
90MAPK130.26366996
91PRKACA0.25455131
92CDK11A0.24225598
93TGFBR20.24133777
94CSNK1A10.23961530
95PRKD10.23883607
96PRKD30.22986637
97MAP3K80.21767273
98EEF2K0.20525379
99PLK10.18953230
100MAP3K50.18520519

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005114.82106011
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001304.19365114
3Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.62219825
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.45010352
5Phototransduction_Homo sapiens_hsa047443.14315603
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.76412254
7Primary immunodeficiency_Homo sapiens_hsa053402.59938827
8Nitrogen metabolism_Homo sapiens_hsa009102.38381723
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.28210349
10Fanconi anemia pathway_Homo sapiens_hsa034602.11265692
11Sphingolipid metabolism_Homo sapiens_hsa006002.10036615
12Base excision repair_Homo sapiens_hsa034102.01218254
13Ribosome_Homo sapiens_hsa030102.00930397
14Taste transduction_Homo sapiens_hsa047421.78005712
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.63145100
16Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.60645103
17RNA degradation_Homo sapiens_hsa030181.55338811
18mTOR signaling pathway_Homo sapiens_hsa041501.53222902
19Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.50077079
20Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.46412297
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43239279
22Autoimmune thyroid disease_Homo sapiens_hsa053201.42170619
23Glycosaminoglycan degradation_Homo sapiens_hsa005311.41173263
24Intestinal immune network for IgA production_Homo sapiens_hsa046721.39298618
25Primary bile acid biosynthesis_Homo sapiens_hsa001201.38641578
26Linoleic acid metabolism_Homo sapiens_hsa005911.37349762
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.30259062
28Bladder cancer_Homo sapiens_hsa052191.16643026
29Sulfur relay system_Homo sapiens_hsa041221.14368295
30Graft-versus-host disease_Homo sapiens_hsa053321.12338286
31Allograft rejection_Homo sapiens_hsa053301.10997304
32Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.05177404
33Chemical carcinogenesis_Homo sapiens_hsa052041.03079958
34Hematopoietic cell lineage_Homo sapiens_hsa046400.97538683
35Fructose and mannose metabolism_Homo sapiens_hsa000510.94068053
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91733941
37Vitamin B6 metabolism_Homo sapiens_hsa007500.87454110
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.86420438
39Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84333699
40NF-kappa B signaling pathway_Homo sapiens_hsa040640.81297754
41Ovarian steroidogenesis_Homo sapiens_hsa049130.79746075
42Chemokine signaling pathway_Homo sapiens_hsa040620.78289526
43Antigen processing and presentation_Homo sapiens_hsa046120.77775268
44Glycerophospholipid metabolism_Homo sapiens_hsa005640.77343616
45Ether lipid metabolism_Homo sapiens_hsa005650.76879999
46Olfactory transduction_Homo sapiens_hsa047400.76284356
47Glycerolipid metabolism_Homo sapiens_hsa005610.75644284
48Vitamin digestion and absorption_Homo sapiens_hsa049770.72154258
49Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72036996
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70009620
51Calcium signaling pathway_Homo sapiens_hsa040200.69860951
52Hedgehog signaling pathway_Homo sapiens_hsa043400.69432826
53NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69238460
54Platelet activation_Homo sapiens_hsa046110.68876658
55Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.66931312
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.65281849
57HTLV-I infection_Homo sapiens_hsa051660.65138987
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63610404
59Histidine metabolism_Homo sapiens_hsa003400.62890355
60Hepatitis C_Homo sapiens_hsa051600.62378828
61Arachidonic acid metabolism_Homo sapiens_hsa005900.61866888
62Drug metabolism - other enzymes_Homo sapiens_hsa009830.61706134
63Osteoclast differentiation_Homo sapiens_hsa043800.60872049
64Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60338382
65Leishmaniasis_Homo sapiens_hsa051400.58636427
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58439326
67Collecting duct acid secretion_Homo sapiens_hsa049660.58056613
68T cell receptor signaling pathway_Homo sapiens_hsa046600.58022214
69Lysosome_Homo sapiens_hsa041420.57331839
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56954083
71Serotonergic synapse_Homo sapiens_hsa047260.55257019
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52254648
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.51408925
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.49954551
75Tuberculosis_Homo sapiens_hsa051520.48005384
76Rheumatoid arthritis_Homo sapiens_hsa053230.46300805
77Type I diabetes mellitus_Homo sapiens_hsa049400.45792073
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45631315
79Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44006557
80Staphylococcus aureus infection_Homo sapiens_hsa051500.43943057
81Herpes simplex infection_Homo sapiens_hsa051680.42657212
82Asthma_Homo sapiens_hsa053100.42126056
83Prion diseases_Homo sapiens_hsa050200.40797089
84Measles_Homo sapiens_hsa051620.38791567
85Spliceosome_Homo sapiens_hsa030400.37699471
86Morphine addiction_Homo sapiens_hsa050320.35783467
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.35271512
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33858446
89Endocytosis_Homo sapiens_hsa041440.33567621
90Notch signaling pathway_Homo sapiens_hsa043300.32118698
91Circadian rhythm_Homo sapiens_hsa047100.30814361
92Systemic lupus erythematosus_Homo sapiens_hsa053220.30369597
93Non-homologous end-joining_Homo sapiens_hsa034500.28633411
94Alcoholism_Homo sapiens_hsa050340.26408409
95Dorso-ventral axis formation_Homo sapiens_hsa043200.25161167
96B cell receptor signaling pathway_Homo sapiens_hsa046620.25020527
97Viral carcinogenesis_Homo sapiens_hsa052030.23418858
98Cell cycle_Homo sapiens_hsa041100.22918889
99Retinol metabolism_Homo sapiens_hsa008300.22692342
100Tryptophan metabolism_Homo sapiens_hsa003800.21513091

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »