

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pseudouridine synthesis (GO:0001522) | 8.58466977 |
| 2 | oligosaccharide catabolic process (GO:0009313) | 7.64631685 |
| 3 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 6.75784513 |
| 4 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 6.16191293 |
| 5 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 5.94032673 |
| 6 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 5.78602805 |
| 7 | chemosensory behavior (GO:0007635) | 5.73521708 |
| 8 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 5.45424214 |
| 9 | cellular response to ATP (GO:0071318) | 5.27306240 |
| 10 | regulation of mitotic spindle organization (GO:0060236) | 5.18491470 |
| 11 | outer ear morphogenesis (GO:0042473) | 5.12951893 |
| 12 | DNA deamination (GO:0045006) | 5.02146432 |
| 13 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 4.95614757 |
| 14 | post-embryonic morphogenesis (GO:0009886) | 4.92552066 |
| 15 | NIK/NF-kappaB signaling (GO:0038061) | 4.81650120 |
| 16 | negative regulation of cell aging (GO:0090344) | 4.77136597 |
| 17 | positive regulation of microtubule polymerization (GO:0031116) | 4.72288673 |
| 18 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.70775431 |
| 19 | positive regulation of B cell differentiation (GO:0045579) | 4.65144959 |
| 20 | regulation of skeletal muscle contraction (GO:0014819) | 4.38203135 |
| 21 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 4.37926409 |
| 22 | detection of light stimulus involved in visual perception (GO:0050908) | 4.07669562 |
| 23 | detection of light stimulus involved in sensory perception (GO:0050962) | 4.07669562 |
| 24 | negative regulation of B cell proliferation (GO:0030889) | 4.04082237 |
| 25 | activated T cell proliferation (GO:0050798) | 4.00869646 |
| 26 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.91952435 |
| 27 | negative regulation of Ras GTPase activity (GO:0034261) | 3.91590405 |
| 28 | branching involved in prostate gland morphogenesis (GO:0060442) | 3.81815736 |
| 29 | meiotic chromosome segregation (GO:0045132) | 3.78772845 |
| 30 | positive regulation of megakaryocyte differentiation (GO:0045654) | 3.76879989 |
| 31 | regulation of RIG-I signaling pathway (GO:0039535) | 3.71320917 |
| 32 | base-excision repair, AP site formation (GO:0006285) | 3.70695054 |
| 33 | positive regulation of granulocyte differentiation (GO:0030854) | 3.67498528 |
| 34 | trophectodermal cell differentiation (GO:0001829) | 3.65982657 |
| 35 | cellular response to dsRNA (GO:0071359) | 3.63518268 |
| 36 | microtubule depolymerization (GO:0007019) | 3.63318598 |
| 37 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 3.61384287 |
| 38 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.57680134 |
| 39 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.55917026 |
| 40 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 3.51251041 |
| 41 | histone H2A monoubiquitination (GO:0035518) | 3.46841396 |
| 42 | peristalsis (GO:0030432) | 3.46752930 |
| 43 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.44906838 |
| 44 | negative regulation of interleukin-17 production (GO:0032700) | 3.41477046 |
| 45 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.41082059 |
| 46 | melanin biosynthetic process (GO:0042438) | 3.40069365 |
| 47 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.39814612 |
| 48 | protein carboxylation (GO:0018214) | 3.39814612 |
| 49 | negative regulation of DNA repair (GO:0045738) | 3.38381916 |
| 50 | GDP-mannose metabolic process (GO:0019673) | 3.34045780 |
| 51 | cell wall macromolecule catabolic process (GO:0016998) | 3.33747368 |
| 52 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 3.32227110 |
| 53 | mitotic cell cycle arrest (GO:0071850) | 3.30609977 |
| 54 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.29349574 |
| 55 | ribosomal small subunit assembly (GO:0000028) | 3.29331916 |
| 56 | cytokine biosynthetic process (GO:0042089) | 3.28384757 |
| 57 | DNA double-strand break processing (GO:0000729) | 3.27739932 |
| 58 | melanin metabolic process (GO:0006582) | 3.27528095 |
| 59 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.27261146 |
| 60 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.26000846 |
| 61 | phenylpropanoid metabolic process (GO:0009698) | 3.23784392 |
| 62 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.22896121 |
| 63 | positive regulation of actin cytoskeleton reorganization (GO:2000251) | 3.19617396 |
| 64 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 3.16429120 |
| 65 | regulation of B cell differentiation (GO:0045577) | 3.16068874 |
| 66 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.13895325 |
| 67 | transepithelial transport (GO:0070633) | 3.13367665 |
| 68 | regulation of spindle organization (GO:0090224) | 3.13119700 |
| 69 | mitotic metaphase plate congression (GO:0007080) | 3.10936062 |
| 70 | regulation of DNA damage checkpoint (GO:2000001) | 3.08924261 |
| 71 | response to peptidoglycan (GO:0032494) | 3.08380795 |
| 72 | positive regulation of histone methylation (GO:0031062) | 3.07836367 |
| 73 | regulation of protein polyubiquitination (GO:1902914) | 2.99395340 |
| 74 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.97972685 |
| 75 | negative regulation of bone mineralization (GO:0030502) | 2.97366999 |
| 76 | synaptonemal complex assembly (GO:0007130) | 2.97265018 |
| 77 | DNA strand renaturation (GO:0000733) | 2.96090850 |
| 78 | mitotic chromosome condensation (GO:0007076) | 2.95899005 |
| 79 | ganglioside metabolic process (GO:0001573) | 2.95305417 |
| 80 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.93878644 |
| 81 | sensory perception of smell (GO:0007608) | 2.92047520 |
| 82 | DNA dealkylation (GO:0035510) | 2.91185469 |
| 83 | fibroblast migration (GO:0010761) | 2.88736348 |
| 84 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.88544797 |
| 85 | purine ribonucleotide transport (GO:0015868) | 2.87183231 |
| 86 | iron-sulfur cluster assembly (GO:0016226) | 2.80480346 |
| 87 | metallo-sulfur cluster assembly (GO:0031163) | 2.80480346 |
| 88 | granulocyte differentiation (GO:0030851) | 2.79533983 |
| 89 | regulation of defense response to virus by host (GO:0050691) | 2.78657252 |
| 90 | actin nucleation (GO:0045010) | 2.78640872 |
| 91 | cytidine metabolic process (GO:0046087) | 2.76766684 |
| 92 | cytidine catabolic process (GO:0006216) | 2.76766684 |
| 93 | cytidine deamination (GO:0009972) | 2.76766684 |
| 94 | regulation of gamma-delta T cell activation (GO:0046643) | 2.74916792 |
| 95 | positive regulation of TOR signaling (GO:0032008) | 2.74462262 |
| 96 | cytokine metabolic process (GO:0042107) | 2.73231868 |
| 97 | cell wall macromolecule metabolic process (GO:0044036) | 2.71800381 |
| 98 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.71777882 |
| 99 | positive regulation of heat generation (GO:0031652) | 2.65025518 |
| 100 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 2.64228596 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.55893945 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.30118134 |
| 3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 5.10487932 |
| 4 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.88769857 |
| 5 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.22113598 |
| 6 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.97911115 |
| 7 | BCL6_27268052_Chip-Seq_Bcells_Human | 2.34287438 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.23216989 |
| 9 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.19882614 |
| 10 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 2.13421663 |
| 11 | P68_20966046_ChIP-Seq_HELA_Human | 2.09727172 |
| 12 | MYC_22102868_ChIP-Seq_BL_Human | 2.09702972 |
| 13 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.08061499 |
| 14 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.05564473 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.95945703 |
| 16 | MAF_26560356_Chip-Seq_TH2_Human | 1.94853000 |
| 17 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.92057622 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.89867744 |
| 19 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.89258625 |
| 20 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.87601612 |
| 21 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.82111705 |
| 22 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.82004571 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.81042452 |
| 24 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.79547601 |
| 25 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.74131469 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 1.72150307 |
| 27 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.69776523 |
| 28 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.66690471 |
| 29 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.63414507 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.59945130 |
| 31 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.58509619 |
| 32 | P300_27268052_Chip-Seq_Bcells_Human | 1.57716358 |
| 33 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.53534946 |
| 34 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.52570452 |
| 35 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.50848101 |
| 36 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.47007336 |
| 37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.46934184 |
| 38 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.44564025 |
| 39 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.41543499 |
| 40 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.41010806 |
| 41 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.40804066 |
| 42 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.39551571 |
| 43 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.33725077 |
| 44 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.33309777 |
| 45 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.32747904 |
| 46 | CTCF_21964334_Chip-Seq_Bcells_Human | 1.30815108 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.29090348 |
| 48 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.27920516 |
| 49 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.27840350 |
| 50 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.27757845 |
| 51 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.27515722 |
| 52 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.27445658 |
| 53 | UTX_26944678_Chip-Seq_JUKART_Human | 1.26928919 |
| 54 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.25888638 |
| 55 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.24784823 |
| 56 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.24750261 |
| 57 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.23714451 |
| 58 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.21836296 |
| 59 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.21574102 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.20285460 |
| 61 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.19848152 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.18680313 |
| 63 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.16786960 |
| 64 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.16389273 |
| 65 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.15949291 |
| 66 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14678020 |
| 67 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11721719 |
| 68 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.09850234 |
| 69 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.09249003 |
| 70 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.08789081 |
| 71 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.08785188 |
| 72 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08319168 |
| 73 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.08167655 |
| 74 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.05691298 |
| 75 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.05384613 |
| 76 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.03311151 |
| 77 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.03105710 |
| 78 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.02268090 |
| 79 | GATA1_19941826_ChIP-Seq_K562_Human | 1.01353368 |
| 80 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98912643 |
| 81 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.98846825 |
| 82 | SA1_27219007_Chip-Seq_Bcells_Human | 0.97575298 |
| 83 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.97042195 |
| 84 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.96770671 |
| 85 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96604254 |
| 86 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.96322488 |
| 87 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.96112522 |
| 88 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.96077217 |
| 89 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.94920069 |
| 90 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.94588028 |
| 91 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.94074741 |
| 92 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.93985338 |
| 93 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.93282176 |
| 94 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.92917472 |
| 95 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92834991 |
| 96 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.92669050 |
| 97 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.91646409 |
| 98 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.90933665 |
| 99 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90645958 |
| 100 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90195277 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 5.66932391 |
| 2 | MP0005451_abnormal_body_composition | 4.79070740 |
| 3 | MP0005174_abnormal_tail_pigmentation | 4.59989112 |
| 4 | MP0005083_abnormal_biliary_tract | 3.79046369 |
| 5 | MP0003329_amyloid_beta_deposits | 3.66662373 |
| 6 | MP0003136_yellow_coat_color | 3.62382389 |
| 7 | MP0005171_absent_coat_pigmentation | 3.52358021 |
| 8 | MP0000604_amyloidosis | 2.68947525 |
| 9 | MP0003567_abnormal_fetal_cardiomyocyte | 2.52426535 |
| 10 | MP0001986_abnormal_taste_sensitivity | 2.38416940 |
| 11 | MP0003011_delayed_dark_adaptation | 2.38094765 |
| 12 | MP0005397_hematopoietic_system_phenotyp | 2.32264704 |
| 13 | MP0001545_abnormal_hematopoietic_system | 2.32264704 |
| 14 | MP0000015_abnormal_ear_pigmentation | 2.20605811 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.18258647 |
| 16 | MP0000566_synostosis | 2.09931302 |
| 17 | MP0000685_abnormal_immune_system | 1.99729792 |
| 18 | MP0006072_abnormal_retinal_apoptosis | 1.97367924 |
| 19 | MP0009046_muscle_twitch | 1.93154755 |
| 20 | MP0003045_fibrosis | 1.89491526 |
| 21 | MP0001873_stomach_inflammation | 1.74186386 |
| 22 | MP0005671_abnormal_response_to | 1.65946270 |
| 23 | MP0005423_abnormal_somatic_nervous | 1.63138984 |
| 24 | MP0005253_abnormal_eye_physiology | 1.62830972 |
| 25 | MP0009278_abnormal_bone_marrow | 1.48647377 |
| 26 | MP0002638_abnormal_pupillary_reflex | 1.44322557 |
| 27 | MP0002398_abnormal_bone_marrow | 1.31476673 |
| 28 | MP0000689_abnormal_spleen_morphology | 1.30865001 |
| 29 | MP0003763_abnormal_thymus_physiology | 1.25645848 |
| 30 | MP0003693_abnormal_embryo_hatching | 1.23764708 |
| 31 | MP0001790_abnormal_immune_system | 1.21835656 |
| 32 | MP0005387_immune_system_phenotype | 1.21835656 |
| 33 | MP0005464_abnormal_platelet_physiology | 1.20920736 |
| 34 | MP0002160_abnormal_reproductive_system | 1.20293137 |
| 35 | MP0005410_abnormal_fertilization | 1.19853524 |
| 36 | MP0005084_abnormal_gallbladder_morpholo | 1.19354129 |
| 37 | MP0002722_abnormal_immune_system | 1.18672138 |
| 38 | MP0005332_abnormal_amino_acid | 1.17337523 |
| 39 | MP0002254_reproductive_system_inflammat | 1.13928552 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.13050869 |
| 41 | MP0005058_abnormal_lysosome_morphology | 1.11218930 |
| 42 | MP0001800_abnormal_humoral_immune | 1.10970501 |
| 43 | MP0002148_abnormal_hypersensitivity_rea | 1.10884870 |
| 44 | MP0004381_abnormal_hair_follicle | 1.07857723 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.06562245 |
| 46 | MP0003137_abnormal_impulse_conducting | 1.06499956 |
| 47 | MP0005551_abnormal_eye_electrophysiolog | 1.05883405 |
| 48 | MP0000716_abnormal_immune_system | 1.03639730 |
| 49 | MP0003632_abnormal_nervous_system | 1.01493031 |
| 50 | MP0001765_abnormal_ion_homeostasis | 0.99009839 |
| 51 | MP0002420_abnormal_adaptive_immunity | 0.97793850 |
| 52 | MP0002452_abnormal_antigen_presenting | 0.96401780 |
| 53 | MP0001485_abnormal_pinna_reflex | 0.94709748 |
| 54 | MP0001819_abnormal_immune_cell | 0.94466517 |
| 55 | MP0003718_maternal_effect | 0.93247589 |
| 56 | MP0005000_abnormal_immune_tolerance | 0.92734713 |
| 57 | MP0002723_abnormal_immune_serum | 0.92384718 |
| 58 | MP0001756_abnormal_urination | 0.91481597 |
| 59 | MP0008789_abnormal_olfactory_epithelium | 0.90737762 |
| 60 | MP0002405_respiratory_system_inflammati | 0.89797156 |
| 61 | MP0001666_abnormal_nutrient_absorption | 0.89076814 |
| 62 | MP0002429_abnormal_blood_cell | 0.88672518 |
| 63 | MP0005025_abnormal_response_to | 0.88568851 |
| 64 | MP0000703_abnormal_thymus_morphology | 0.88055763 |
| 65 | MP0001502_abnormal_circadian_rhythm | 0.86805038 |
| 66 | MP0005499_abnormal_olfactory_system | 0.85929831 |
| 67 | MP0005394_taste/olfaction_phenotype | 0.85929831 |
| 68 | MP0001963_abnormal_hearing_physiology | 0.85872668 |
| 69 | MP0001853_heart_inflammation | 0.85659403 |
| 70 | MP0003806_abnormal_nucleotide_metabolis | 0.84024767 |
| 71 | MP0009333_abnormal_splenocyte_physiolog | 0.83874909 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.83161875 |
| 73 | MP0001905_abnormal_dopamine_level | 0.82899320 |
| 74 | MP0000516_abnormal_urinary_system | 0.82473732 |
| 75 | MP0005367_renal/urinary_system_phenotyp | 0.82473732 |
| 76 | MP0002933_joint_inflammation | 0.80344276 |
| 77 | MP0009643_abnormal_urine_homeostasis | 0.79581202 |
| 78 | MP0000049_abnormal_middle_ear | 0.78097048 |
| 79 | MP0000751_myopathy | 0.77276852 |
| 80 | MP0003943_abnormal_hepatobiliary_system | 0.76368301 |
| 81 | MP0002138_abnormal_hepatobiliary_system | 0.74943219 |
| 82 | MP0003866_abnormal_defecation | 0.74866483 |
| 83 | MP0001919_abnormal_reproductive_system | 0.74827003 |
| 84 | MP0004808_abnormal_hematopoietic_stem | 0.74159396 |
| 85 | MP0003656_abnormal_erythrocyte_physiolo | 0.72366073 |
| 86 | MP0002229_neurodegeneration | 0.70313612 |
| 87 | MP0000371_diluted_coat_color | 0.69894516 |
| 88 | MP0002106_abnormal_muscle_physiology | 0.69441277 |
| 89 | MP0001501_abnormal_sleep_pattern | 0.68612258 |
| 90 | MP0001929_abnormal_gametogenesis | 0.67292524 |
| 91 | MP0006036_abnormal_mitochondrial_physio | 0.66999671 |
| 92 | MP0008569_lethality_at_weaning | 0.66903508 |
| 93 | MP0005389_reproductive_system_phenotype | 0.64565177 |
| 94 | MP0008469_abnormal_protein_level | 0.64017667 |
| 95 | MP0000013_abnormal_adipose_tissue | 0.63229978 |
| 96 | MP0005395_other_phenotype | 0.62991534 |
| 97 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.60128372 |
| 98 | MP0008872_abnormal_physiological_respon | 0.58153367 |
| 99 | MP0000026_abnormal_inner_ear | 0.57059428 |
| 100 | MP0002067_abnormal_sensory_capabilities | 0.56820710 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.90691462 |
| 2 | Congenital stationary night blindness (HP:0007642) | 5.72752944 |
| 3 | Duplicated collecting system (HP:0000081) | 5.50166799 |
| 4 | Abnormal biliary tract physiology (HP:0012439) | 5.42773315 |
| 5 | Bile duct proliferation (HP:0001408) | 5.42773315 |
| 6 | Abnormality of the renal collecting system (HP:0004742) | 5.31207991 |
| 7 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.86529550 |
| 8 | Vacuolated lymphocytes (HP:0001922) | 4.70638514 |
| 9 | Global brain atrophy (HP:0002283) | 4.63651114 |
| 10 | Abnormality of pyrimidine metabolism (HP:0004353) | 4.07686422 |
| 11 | Chromsome breakage (HP:0040012) | 4.01742918 |
| 12 | Abnormality of DNA repair (HP:0003254) | 3.95280086 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.82377242 |
| 14 | Molar tooth sign on MRI (HP:0002419) | 3.82377242 |
| 15 | Bifid tongue (HP:0010297) | 3.76643053 |
| 16 | Optic nerve coloboma (HP:0000588) | 3.72907061 |
| 17 | Impaired smooth pursuit (HP:0007772) | 3.62823631 |
| 18 | Hypercortisolism (HP:0001578) | 3.61766599 |
| 19 | Absent thumb (HP:0009777) | 3.51764122 |
| 20 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.24139609 |
| 21 | Ureteral duplication (HP:0000073) | 3.13845415 |
| 22 | Failure to thrive in infancy (HP:0001531) | 3.08297520 |
| 23 | Attenuation of retinal blood vessels (HP:0007843) | 3.07032144 |
| 24 | Testicular atrophy (HP:0000029) | 3.01568719 |
| 25 | Limb dystonia (HP:0002451) | 2.93280109 |
| 26 | Recurrent cutaneous fungal infections (HP:0011370) | 2.84402181 |
| 27 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.84402181 |
| 28 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.83895976 |
| 29 | Clubbing of toes (HP:0100760) | 2.79662123 |
| 30 | Prolonged partial thromboplastin time (HP:0003645) | 2.78684436 |
| 31 | Ectopic kidney (HP:0000086) | 2.78282968 |
| 32 | Increased cerebral lipofuscin (HP:0011813) | 2.77814334 |
| 33 | Lipid accumulation in hepatocytes (HP:0006561) | 2.73659074 |
| 34 | Annular pancreas (HP:0001734) | 2.69682386 |
| 35 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.69643398 |
| 36 | Asplenia (HP:0001746) | 2.64296095 |
| 37 | Truncal obesity (HP:0001956) | 2.62077785 |
| 38 | Abnormal pupillary function (HP:0007686) | 2.61279721 |
| 39 | True hermaphroditism (HP:0010459) | 2.61204089 |
| 40 | Abnormality of the intrinsic pathway (HP:0010989) | 2.60167074 |
| 41 | Absent radius (HP:0003974) | 2.59318224 |
| 42 | Joint hemorrhage (HP:0005261) | 2.51656451 |
| 43 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.50923160 |
| 44 | Dyschromatopsia (HP:0007641) | 2.50811006 |
| 45 | Increased hepatocellular lipid droplets (HP:0006565) | 2.49873071 |
| 46 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.49213631 |
| 47 | Aplasia involving forearm bones (HP:0009822) | 2.46136467 |
| 48 | Absent forearm bone (HP:0003953) | 2.46136467 |
| 49 | Increased muscle lipid content (HP:0009058) | 2.42870937 |
| 50 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.42459146 |
| 51 | Mesangial abnormality (HP:0001966) | 2.41568842 |
| 52 | Hemiparesis (HP:0001269) | 2.39747249 |
| 53 | Neurofibrillary tangles (HP:0002185) | 2.37035028 |
| 54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.36233148 |
| 55 | Duplication of thumb phalanx (HP:0009942) | 2.33663832 |
| 56 | Pancreatic fibrosis (HP:0100732) | 2.33238949 |
| 57 | Abnormality of reticulocytes (HP:0004312) | 2.32257453 |
| 58 | Rib fusion (HP:0000902) | 2.32121325 |
| 59 | Epiphyseal dysplasia (HP:0002656) | 2.30575242 |
| 60 | Meckel diverticulum (HP:0002245) | 2.29379129 |
| 61 | Panhypogammaglobulinemia (HP:0003139) | 2.28745673 |
| 62 | Nephronophthisis (HP:0000090) | 2.27498920 |
| 63 | Diplopia (HP:0000651) | 2.24487098 |
| 64 | Abnormality of binocular vision (HP:0011514) | 2.24487098 |
| 65 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.23976404 |
| 66 | Confusion (HP:0001289) | 2.23009258 |
| 67 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.22905525 |
| 68 | Pancreatic cysts (HP:0001737) | 2.21686211 |
| 69 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20635570 |
| 70 | Pallor (HP:0000980) | 2.11321342 |
| 71 | Rectal fistula (HP:0100590) | 2.11015405 |
| 72 | Rectovaginal fistula (HP:0000143) | 2.11015405 |
| 73 | Tachypnea (HP:0002789) | 2.10965238 |
| 74 | Facial diplegia (HP:0001349) | 2.10830895 |
| 75 | Abnormality of the ileum (HP:0001549) | 2.08247072 |
| 76 | Premature graying of hair (HP:0002216) | 2.06964536 |
| 77 | Renal Fanconi syndrome (HP:0001994) | 2.05199904 |
| 78 | Myelodysplasia (HP:0002863) | 2.04663220 |
| 79 | Abnormal number of erythroid precursors (HP:0012131) | 2.03693258 |
| 80 | Hypoplasia of the brainstem (HP:0002365) | 2.03053603 |
| 81 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.03053603 |
| 82 | Gastrointestinal inflammation (HP:0004386) | 2.02600284 |
| 83 | Inflammation of the large intestine (HP:0002037) | 2.02351343 |
| 84 | Abnormality of the preputium (HP:0100587) | 2.00917986 |
| 85 | Severe global developmental delay (HP:0011344) | 2.00184420 |
| 86 | Exercise-induced myalgia (HP:0003738) | 1.98858485 |
| 87 | Facial hemangioma (HP:0000329) | 1.96139779 |
| 88 | Abnormality of the common coagulation pathway (HP:0010990) | 1.93541031 |
| 89 | Poikiloderma (HP:0001029) | 1.90532290 |
| 90 | Recurrent fungal infections (HP:0002841) | 1.86903709 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.86877299 |
| 92 | Decreased central vision (HP:0007663) | 1.86508089 |
| 93 | Aplasia of the musculature (HP:0100854) | 1.84177077 |
| 94 | Intestinal fistula (HP:0100819) | 1.83515487 |
| 95 | Febrile seizures (HP:0002373) | 1.82811653 |
| 96 | Dysautonomia (HP:0002459) | 1.81785769 |
| 97 | Esophageal neoplasm (HP:0100751) | 1.81727918 |
| 98 | Neoplasm of head and neck (HP:0012288) | 1.81727918 |
| 99 | Bradykinesia (HP:0002067) | 1.81622634 |
| 100 | Hemorrhage of the eye (HP:0011885) | 1.80391919 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK1 | 6.52852593 |
| 2 | ADRBK2 | 4.66406163 |
| 3 | MAPK15 | 4.44941718 |
| 4 | TESK2 | 4.31441977 |
| 5 | FGFR3 | 3.10594567 |
| 6 | BUB1 | 3.09439244 |
| 7 | PIM2 | 3.01645142 |
| 8 | TXK | 2.71789380 |
| 9 | NME2 | 2.58000637 |
| 10 | TBK1 | 2.23572747 |
| 11 | DDR2 | 2.03965520 |
| 12 | CCNB1 | 1.85107426 |
| 13 | DYRK1A | 1.71222923 |
| 14 | SCYL2 | 1.55127901 |
| 15 | TAOK1 | 1.51422793 |
| 16 | ADRBK1 | 1.49730517 |
| 17 | MAP3K1 | 1.47256891 |
| 18 | MAP3K14 | 1.45983506 |
| 19 | RAF1 | 1.44253807 |
| 20 | IKBKE | 1.32557558 |
| 21 | MAP4K2 | 1.29630033 |
| 22 | BLK | 1.29338091 |
| 23 | MAP4K1 | 1.29204235 |
| 24 | NTRK3 | 1.23775004 |
| 25 | MAPK12 | 1.21674836 |
| 26 | MAP3K4 | 1.21175674 |
| 27 | MUSK | 1.19995780 |
| 28 | VRK1 | 1.10739087 |
| 29 | GRK6 | 1.10291225 |
| 30 | SYK | 1.04294590 |
| 31 | JAK3 | 0.97336464 |
| 32 | IKBKB | 0.91118913 |
| 33 | DAPK2 | 0.89492468 |
| 34 | PKN2 | 0.89322826 |
| 35 | IRAK1 | 0.85478549 |
| 36 | RPS6KA6 | 0.84941861 |
| 37 | RPS6KC1 | 0.84938053 |
| 38 | RPS6KL1 | 0.84938053 |
| 39 | PIM1 | 0.84130794 |
| 40 | TLK1 | 0.82889471 |
| 41 | WNK4 | 0.82737909 |
| 42 | NEK2 | 0.82519728 |
| 43 | IRAK3 | 0.80834886 |
| 44 | SIK2 | 0.77985551 |
| 45 | CDK3 | 0.77644189 |
| 46 | DYRK2 | 0.74733788 |
| 47 | RPS6KB2 | 0.73918522 |
| 48 | FLT3 | 0.70687059 |
| 49 | DYRK1B | 0.68584839 |
| 50 | CDK4 | 0.67268532 |
| 51 | PTK2B | 0.65798345 |
| 52 | LATS1 | 0.65605527 |
| 53 | UHMK1 | 0.65503265 |
| 54 | AURKA | 0.63255824 |
| 55 | MAP2K2 | 0.61933219 |
| 56 | NUAK1 | 0.59703052 |
| 57 | CSK | 0.58679392 |
| 58 | PRKD2 | 0.58477780 |
| 59 | ZAK | 0.56163042 |
| 60 | RPS6KA5 | 0.55539637 |
| 61 | MAP3K2 | 0.54861368 |
| 62 | PBK | 0.53494658 |
| 63 | RET | 0.52849030 |
| 64 | LYN | 0.50555963 |
| 65 | TAOK2 | 0.49202775 |
| 66 | MAPK3 | 0.48862855 |
| 67 | MARK3 | 0.48176631 |
| 68 | CHEK2 | 0.45365474 |
| 69 | FES | 0.45196326 |
| 70 | RPS6KA2 | 0.43743194 |
| 71 | ERN1 | 0.43321237 |
| 72 | MAP2K3 | 0.41304241 |
| 73 | PAK1 | 0.41152701 |
| 74 | MAPK7 | 0.40938108 |
| 75 | TAOK3 | 0.40840223 |
| 76 | CDK5 | 0.40567927 |
| 77 | TRIM28 | 0.39928837 |
| 78 | IRAK2 | 0.39028285 |
| 79 | TRPM7 | 0.38192643 |
| 80 | MAPK11 | 0.35422710 |
| 81 | AKT2 | 0.33988043 |
| 82 | PRKCQ | 0.33749487 |
| 83 | LCK | 0.33737649 |
| 84 | GRK7 | 0.31149036 |
| 85 | ATR | 0.30858435 |
| 86 | JAK2 | 0.30624856 |
| 87 | GRK5 | 0.30421266 |
| 88 | INSR | 0.28044736 |
| 89 | STK38 | 0.26449604 |
| 90 | MAPK13 | 0.26366996 |
| 91 | PRKACA | 0.25455131 |
| 92 | CDK11A | 0.24225598 |
| 93 | TGFBR2 | 0.24133777 |
| 94 | CSNK1A1 | 0.23961530 |
| 95 | PRKD1 | 0.23883607 |
| 96 | PRKD3 | 0.22986637 |
| 97 | MAP3K8 | 0.21767273 |
| 98 | EEF2K | 0.20525379 |
| 99 | PLK1 | 0.18953230 |
| 100 | MAP3K5 | 0.18520519 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Other glycan degradation_Homo sapiens_hsa00511 | 4.82106011 |
| 2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.19365114 |
| 3 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 3.62219825 |
| 4 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.45010352 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 3.14315603 |
| 6 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.76412254 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.59938827 |
| 8 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.38381723 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.28210349 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.11265692 |
| 11 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.10036615 |
| 12 | Base excision repair_Homo sapiens_hsa03410 | 2.01218254 |
| 13 | Ribosome_Homo sapiens_hsa03010 | 2.00930397 |
| 14 | Taste transduction_Homo sapiens_hsa04742 | 1.78005712 |
| 15 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.63145100 |
| 16 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.60645103 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.55338811 |
| 18 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.53222902 |
| 19 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.50077079 |
| 20 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.46412297 |
| 21 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.43239279 |
| 22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.42170619 |
| 23 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.41173263 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.39298618 |
| 25 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.38641578 |
| 26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.37349762 |
| 27 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.30259062 |
| 28 | Bladder cancer_Homo sapiens_hsa05219 | 1.16643026 |
| 29 | Sulfur relay system_Homo sapiens_hsa04122 | 1.14368295 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.12338286 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.10997304 |
| 32 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.05177404 |
| 33 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.03079958 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.97538683 |
| 35 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.94068053 |
| 36 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.91733941 |
| 37 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.87454110 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.86420438 |
| 39 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.84333699 |
| 40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.81297754 |
| 41 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.79746075 |
| 42 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.78289526 |
| 43 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.77775268 |
| 44 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.77343616 |
| 45 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.76879999 |
| 46 | Olfactory transduction_Homo sapiens_hsa04740 | 0.76284356 |
| 47 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.75644284 |
| 48 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.72154258 |
| 49 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72036996 |
| 50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.70009620 |
| 51 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.69860951 |
| 52 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.69432826 |
| 53 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.69238460 |
| 54 | Platelet activation_Homo sapiens_hsa04611 | 0.68876658 |
| 55 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.66931312 |
| 56 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65281849 |
| 57 | HTLV-I infection_Homo sapiens_hsa05166 | 0.65138987 |
| 58 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.63610404 |
| 59 | Histidine metabolism_Homo sapiens_hsa00340 | 0.62890355 |
| 60 | Hepatitis C_Homo sapiens_hsa05160 | 0.62378828 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.61866888 |
| 62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.61706134 |
| 63 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.60872049 |
| 64 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.60338382 |
| 65 | Leishmaniasis_Homo sapiens_hsa05140 | 0.58636427 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58439326 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58056613 |
| 68 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.58022214 |
| 69 | Lysosome_Homo sapiens_hsa04142 | 0.57331839 |
| 70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56954083 |
| 71 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.55257019 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52254648 |
| 73 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51408925 |
| 74 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.49954551 |
| 75 | Tuberculosis_Homo sapiens_hsa05152 | 0.48005384 |
| 76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46300805 |
| 77 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.45792073 |
| 78 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.45631315 |
| 79 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44006557 |
| 80 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.43943057 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.42657212 |
| 82 | Asthma_Homo sapiens_hsa05310 | 0.42126056 |
| 83 | Prion diseases_Homo sapiens_hsa05020 | 0.40797089 |
| 84 | Measles_Homo sapiens_hsa05162 | 0.38791567 |
| 85 | Spliceosome_Homo sapiens_hsa03040 | 0.37699471 |
| 86 | Morphine addiction_Homo sapiens_hsa05032 | 0.35783467 |
| 87 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.35271512 |
| 88 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.33858446 |
| 89 | Endocytosis_Homo sapiens_hsa04144 | 0.33567621 |
| 90 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32118698 |
| 91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.30814361 |
| 92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30369597 |
| 93 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.28633411 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.26408409 |
| 95 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.25161167 |
| 96 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.25020527 |
| 97 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.23418858 |
| 98 | Cell cycle_Homo sapiens_hsa04110 | 0.22918889 |
| 99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.22692342 |
| 100 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.21513091 |

