PRAM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1defense response to fungus (GO:0050832)9.03374587
2disruption of cells of other organism involved in symbiotic interaction (GO:0051818)7.60459169
3killing of cells in other organism involved in symbiotic interaction (GO:0051883)7.60459169
4response to fungus (GO:0009620)7.24187364
5sequestering of metal ion (GO:0051238)7.03134660
6response to peptidoglycan (GO:0032494)6.73427422
7neutrophil mediated immunity (GO:0002446)6.59916026
8cellular extravasation (GO:0045123)6.40219545
9respiratory burst (GO:0045730)5.97109373
10neutrophil activation involved in immune response (GO:0002283)5.90068068
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.82060390
12negative regulation of cell killing (GO:0031342)5.82060390
13disruption of cells of other organism (GO:0044364)5.68076791
14killing of cells of other organism (GO:0031640)5.68076791
15neutrophil activation (GO:0042119)5.40181081
16myeloid leukocyte mediated immunity (GO:0002444)5.18681125
17antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.07846564
18antigen processing and presentation of endogenous antigen (GO:0019883)5.07470346
19chronic inflammatory response (GO:0002544)4.96872168
20neutrophil chemotaxis (GO:0030593)4.92761616
21granulocyte activation (GO:0036230)4.91398665
22positive regulation of mast cell activation (GO:0033005)4.91165561
23macrophage differentiation (GO:0030225)4.90826785
24regulation of B cell receptor signaling pathway (GO:0050855)4.82069596
25neutrophil migration (GO:1990266)4.79168701
26antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.62655989
27negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.56418708
28negative regulation of phagocytosis (GO:0050765)4.49754627
29microglial cell activation (GO:0001774)4.28102231
30reactive oxygen species biosynthetic process (GO:1903409)4.24660643
31regulation of mast cell degranulation (GO:0043304)4.23194738
32granulocyte migration (GO:0097530)4.22949250
33regulation of mast cell activation (GO:0033003)4.20640460
34antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.20101557
35positive regulation of mast cell degranulation (GO:0043306)4.16665826
36positive regulation of mast cell activation involved in immune response (GO:0033008)4.16665826
37granulocyte chemotaxis (GO:0071621)4.13889012
38response to host immune response (GO:0052572)4.12591009
39response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.12591009
40regulation of gamma-delta T cell activation (GO:0046643)4.08869141
41detection of external biotic stimulus (GO:0098581)4.07407092
42modulation of growth of symbiont involved in interaction with host (GO:0044144)4.07303658
43regulation of growth of symbiont in host (GO:0044126)4.07303658
44negative regulation of growth of symbiont in host (GO:0044130)4.07303658
45negative regulation of growth of symbiont involved in interaction with host (GO:0044146)4.07303658
46leukocyte cell-cell adhesion (GO:0007159)4.01635811
47hydrogen peroxide biosynthetic process (GO:0050665)4.01597981
48regulation of mast cell activation involved in immune response (GO:0033006)3.97174537
49negative regulation of lymphocyte mediated immunity (GO:0002707)3.92054846
50production of molecular mediator involved in inflammatory response (GO:0002532)3.91222537
51superoxide anion generation (GO:0042554)3.91157695
52Arp2/3 complex-mediated actin nucleation (GO:0034314)3.90753404
53detection of bacterium (GO:0016045)3.83942597
54response to host (GO:0075136)3.82859427
55response to host defenses (GO:0052200)3.82859427
56response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.82859427
57detection of other organism (GO:0098543)3.78524471
58negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.72103724
59macrophage activation (GO:0042116)3.69392715
60detection of biotic stimulus (GO:0009595)3.69119350
61negative regulation of T cell mediated immunity (GO:0002710)3.66496156
62pentose-phosphate shunt (GO:0006098)3.65644781
63regulation of gamma-delta T cell differentiation (GO:0045586)3.63209082
64leukotriene metabolic process (GO:0006691)3.60848172
65leukocyte mediated cytotoxicity (GO:0001909)3.57934578
66* regulation of myeloid leukocyte mediated immunity (GO:0002886)3.55737293
67negative regulation of erythrocyte differentiation (GO:0045647)3.54227667
68negative regulation of leukocyte mediated immunity (GO:0002704)3.50400554
69B cell mediated immunity (GO:0019724)3.50225359
70cell killing (GO:0001906)3.49747737
71positive regulation of gamma-delta T cell activation (GO:0046645)3.48671349
72regulation of interferon-beta biosynthetic process (GO:0045357)3.47995489
73positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.46600048
74positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.46312746
75negative regulation of interleukin-6 production (GO:0032715)3.43207427
76phagosome maturation (GO:0090382)3.43172581
77modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.41531709
78positive regulation by organism of defense response of other organism involved in symbiotic interact3.41531709
79modulation by symbiont of host immune response (GO:0052553)3.41531709
80positive regulation by symbiont of host defense response (GO:0052509)3.41531709
81modulation by symbiont of host defense response (GO:0052031)3.41531709
82modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.41531709
83response to muramyl dipeptide (GO:0032495)3.40431673
84* regulation of leukocyte degranulation (GO:0043300)3.40077213
85B cell receptor signaling pathway (GO:0050853)3.38407674
86activated T cell proliferation (GO:0050798)3.37335647
87positive regulation of antigen processing and presentation (GO:0002579)3.34103673
88leukotriene biosynthetic process (GO:0019370)3.33210305
89detection of molecule of bacterial origin (GO:0032490)3.33049605
90defense response to protozoan (GO:0042832)3.30996577
91regulation of B cell differentiation (GO:0045577)3.30421537
92mast cell activation (GO:0045576)3.27014280
93negative thymic T cell selection (GO:0045060)3.22920517
94NADPH regeneration (GO:0006740)3.21953249
95myeloid leukocyte migration (GO:0097529)3.20795483
96antigen processing and presentation via MHC class Ib (GO:0002475)3.19813532
97negative regulation of interleukin-12 production (GO:0032695)3.18987421
98response to interleukin-15 (GO:0070672)3.18761202
99dendritic cell migration (GO:0036336)3.17456947
100regulation of antigen processing and presentation (GO:0002577)3.15898862
101positive regulation of leukocyte degranulation (GO:0043302)3.15777966
102regulation of dendritic cell antigen processing and presentation (GO:0002604)3.15669463
103regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.14908538
104positive thymic T cell selection (GO:0045059)3.13599021
105response to protozoan (GO:0001562)3.11542335
106positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.09837887
107immunoglobulin mediated immune response (GO:0016064)3.08658010
108positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.08088572
109adaptation of signaling pathway (GO:0023058)3.07849135
110negative T cell selection (GO:0043383)3.07387699
111tolerance induction (GO:0002507)3.06827718
112positive regulation of lamellipodium assembly (GO:0010592)3.06465200
113positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.05641728
114negative regulation of T-helper cell differentiation (GO:0045623)3.05439158
115negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.05439158
116regulation of tolerance induction (GO:0002643)3.05306499
117leukocyte degranulation (GO:0043299)3.03670429
118positive regulation of granulocyte differentiation (GO:0030854)3.03186094
119* regulation of regulated secretory pathway (GO:1903305)3.01723468
120negative regulation of innate immune response (GO:0045824)2.99492968
121positive regulation of B cell differentiation (GO:0045579)2.97051195
122innate immune response in mucosa (GO:0002227)2.96707092
123myeloid cell activation involved in immune response (GO:0002275)2.93256241
124leukocyte chemotaxis (GO:0030595)2.92808400
125actin nucleation (GO:0045010)2.92652414
126negative regulation of interleukin-10 production (GO:0032693)2.92013937
127cellular response to interleukin-15 (GO:0071350)2.91962965
128myeloid leukocyte activation (GO:0002274)2.91616937
129macrophage activation involved in immune response (GO:0002281)2.91562670
130negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.91139850
131dendritic cell chemotaxis (GO:0002407)2.89941790
132regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.87314032
133interferon-gamma-mediated signaling pathway (GO:0060333)2.86386436
134antimicrobial humoral response (GO:0019730)2.86204034
135defense response to bacterium (GO:0042742)2.86156106
136positive regulation of toll-like receptor signaling pathway (GO:0034123)2.86081320
137T cell migration (GO:0072678)2.85402937
138negative regulation of interleukin-8 production (GO:0032717)2.83434131
139negative regulation of cytokine production involved in immune response (GO:0002719)2.83356839
140negative regulation of interleukin-1 production (GO:0032692)2.82732102
141negative regulation of granulocyte differentiation (GO:0030853)2.82363048
142defense response to Gram-positive bacterium (GO:0050830)2.82233063
143mucosal immune response (GO:0002385)2.81480173
144regulation of interleukin-6 biosynthetic process (GO:0045408)2.81473033
145antibacterial humoral response (GO:0019731)2.81094423
146positive regulation of osteoblast proliferation (GO:0033690)2.80587691
147regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.80157650
148leukocyte aggregation (GO:0070486)10.6142897
149leukocyte migration involved in inflammatory response (GO:0002523)10.0159981

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.57006259
2* MYB_21317192_ChIP-Seq_ERMYB_Mouse4.43356738
3MECOM_23826213_ChIP-Seq_KASUMI_Mouse4.32276691
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.30435105
5EGR1_19374776_ChIP-ChIP_THP-1_Human4.13173898
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.04865242
7* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.46928144
8FOXM1_23109430_ChIP-Seq_U2OS_Human3.30249352
9VDR_21846776_ChIP-Seq_THP-1_Human3.23142731
10IRF8_27001747_Chip-Seq_BMDM_Mouse3.20988833
11* BRD4_27068464_Chip-Seq_AML-cells_Mouse3.20239878
12* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.15274880
13SCL_19346495_ChIP-Seq_HPC-7_Human3.07854579
14NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.88824323
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.76997691
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.70607994
17* SPI1_23547873_ChIP-Seq_NB4_Human2.68912408
18STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.61670577
19RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.60794961
20IRF8_22096565_ChIP-ChIP_GC-B_Human2.55433378
21VDR_24763502_ChIP-Seq_THP-1_Human2.54098679
22MYC_22102868_ChIP-Seq_BL_Human2.39635283
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.38104712
24MYB_26560356_Chip-Seq_TH2_Human2.35124146
25RUNX1_22412390_ChIP-Seq_EML_Mouse2.34488511
26SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.33805753
27MAF_26560356_Chip-Seq_TH1_Human2.29872599
28SPI1_23127762_ChIP-Seq_K562_Human2.25576705
29UTX_26944678_Chip-Seq_JUKART_Human2.25539291
30FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.24247639
31TCF7_22412390_ChIP-Seq_EML_Mouse2.17350178
32Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.10350909
33* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.03873584
34IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.02614442
35MYB_26560356_Chip-Seq_TH1_Human2.01841754
36STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.98396676
37RUNX_20019798_ChIP-Seq_JUKART_Human1.93213675
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89494271
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.84598496
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.84013603
41SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.83449985
42* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.81557573
43E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.79697900
44VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.78503951
45* PU_27001747_Chip-Seq_BMDM_Mouse1.77130104
46IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.72957721
47CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65198900
48* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.62336892
49* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.57309998
50IKZF1_21737484_ChIP-ChIP_HCT116_Human1.53899751
51KDM2B_26808549_Chip-Seq_DND41_Human1.51386050
52* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.49736879
53RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.48515989
54KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47824315
55VDR_24787735_ChIP-Seq_THP-1_Human1.47081961
56* GATA1_19941827_ChIP-Seq_MEL_Mouse1.45802661
57GATA3_27048872_Chip-Seq_THYMUS_Human1.42977381
58* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.42804334
59TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.41686157
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38700830
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.35693478
62VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.35232155
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33972451
64NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33373107
65CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.33365925
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.33336797
67E2F4_17652178_ChIP-ChIP_JURKAT_Human1.32881459
68MAF_26560356_Chip-Seq_TH2_Human1.32555650
69ELK3_25401928_ChIP-Seq_HUVEC_Human1.31464415
70BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.28507851
71BCOR_27268052_Chip-Seq_Bcells_Human1.27098601
72CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.25884806
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25844723
74PU.1_20513432_ChIP-Seq_Bcells_Mouse1.21451749
75GATA1_19941826_ChIP-Seq_K562_Human1.21033723
76* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.20662157
77CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19790802
78GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.17841489
79* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.17095255
80GATA2_19941826_ChIP-Seq_K562_Human1.16333416
81PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16022081
82RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.15836555
83ELF1_20517297_ChIP-Seq_JURKAT_Human1.14535366
84GATA3_26560356_Chip-Seq_TH2_Human1.11639670
85* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10541381
86CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09334927
87LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08597649
88TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.07193156
89FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.06646364
90EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.06454097
91* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02819187
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01263397
93SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99800534
94FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.98498517
95LXR_22292898_ChIP-Seq_THP-1_Human0.97891976
96SPI1_20517297_ChIP-Seq_HL60_Human0.97780253
97P300_27268052_Chip-Seq_Bcells_Human0.96955675
98KDM2B_26808549_Chip-Seq_JURKAT_Human0.96910583
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95477464
100GATA1_22025678_ChIP-Seq_K562_Human0.95206909
101CIITA_25753668_ChIP-Seq_RAJI_Human0.94365310
102CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92107826
103RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.91415429
104E2F1_20622854_ChIP-Seq_HELA_Human0.91164854
105P68_20966046_ChIP-Seq_HELA_Human0.89554566
106STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.89385514
107NCOR1_26117541_ChIP-Seq_K562_Human0.89199429
108GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88320253
109RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.88082135
110STAT1_20625510_ChIP-Seq_HELA_Human0.85279315
111* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81693645
112THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.79912349
113GATA2_21666600_ChIP-Seq_HMVEC_Human0.78821599
114* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78731611
115PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78460521
116* E2F1_21310950_ChIP-Seq_MCF-7_Human0.78306557
117KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.78187098
118BCL6_27268052_Chip-Seq_Bcells_Human0.78010553
119CTCF_27219007_Chip-Seq_ERYTHROID_Human0.76324771

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation5.38992888
2MP0003436_decreased_susceptibility_to4.73338863
3MP0009785_altered_susceptibility_to3.56420457
4MP0009278_abnormal_bone_marrow3.51226339
5MP0003183_abnormal_peptide_metabolism3.44570756
6* MP0002419_abnormal_innate_immunity3.19679605
7MP0005025_abnormal_response_to2.57514140
8MP0001533_abnormal_skeleton_physiology2.41186024
9MP0001835_abnormal_antigen_presentation2.39458457
10MP0002405_respiratory_system_inflammati2.35090035
11MP0001853_heart_inflammation2.34464930
12MP0005000_abnormal_immune_tolerance2.34445383
13MP0003300_gastrointestinal_ulcer2.30678944
14MP0005397_hematopoietic_system_phenotyp2.23782299
15MP0001545_abnormal_hematopoietic_system2.23782299
16MP0000343_altered_response_to2.23655687
17MP0005464_abnormal_platelet_physiology2.22514980
18MP0001800_abnormal_humoral_immune2.21321407
19MP0000685_abnormal_immune_system2.18129124
20MP0002452_abnormal_antigen_presenting2.16101854
21* MP0002420_abnormal_adaptive_immunity2.15048476
22* MP0001819_abnormal_immune_cell2.13838011
23MP0003724_increased_susceptibility_to2.13480583
24MP0002396_abnormal_hematopoietic_system2.08057104
25MP0004808_abnormal_hematopoietic_stem2.05875596
26MP0005387_immune_system_phenotype2.05826109
27MP0001790_abnormal_immune_system2.05826109
28MP0000569_abnormal_digit_pigmentation2.05462633
29MP0002723_abnormal_immune_serum2.02513497
30MP0000858_altered_metastatic_potential1.99064898
31MP0002148_abnormal_hypersensitivity_rea1.93934101
32MP0000465_gastrointestinal_hemorrhage1.91908391
33MP0001851_eye_inflammation1.89233209
34MP0001845_abnormal_inflammatory_respons1.86032134
35MP0003172_abnormal_lysosome_physiology1.83168689
36MP0002398_abnormal_bone_marrow1.79654663
37MP0001986_abnormal_taste_sensitivity1.76074400
38MP0002837_dystrophic_cardiac_calcinosis1.75385140
39MP0000716_abnormal_immune_system1.72019037
40MP0002166_altered_tumor_susceptibility1.68235932
41MP0002132_abnormal_respiratory_system1.65070128
42MP0004883_abnormal_blood_vessel1.63301285
43MP0005167_abnormal_blood-brain_barrier1.59990703
44MP0005671_abnormal_response_to1.58616478
45MP0010155_abnormal_intestine_physiology1.57029824
46MP0003075_altered_response_to1.54038358
47MP0005076_abnormal_cell_differentiation1.53674197
48MP0005174_abnormal_tail_pigmentation1.51097289
49MP0003191_abnormal_cellular_cholesterol1.50231765
50MP0003448_altered_tumor_morphology1.48706222
51MP0002933_joint_inflammation1.45698190
52MP0002429_abnormal_blood_cell1.45443997
53MP0002722_abnormal_immune_system1.43441234
54MP0000689_abnormal_spleen_morphology1.43423021
55MP0009764_decreased_sensitivity_to1.39364889
56MP0005075_abnormal_melanosome_morpholog1.39279049
57MP0008260_abnormal_autophagy1.38617897
58MP0005058_abnormal_lysosome_morphology1.35681226
59MP0003656_abnormal_erythrocyte_physiolo1.35348492
60MP0004947_skin_inflammation1.32497966
61MP0003806_abnormal_nucleotide_metabolis1.30797246
62MP0001873_stomach_inflammation1.29376823
63MP0003828_pulmonary_edema1.24797792
64MP0005023_abnormal_wound_healing1.23202093
65MP0008469_abnormal_protein_level1.21836075
66MP0003566_abnormal_cell_adhesion1.21459245
67MP0004510_myositis1.20398049
68MP0005164_abnormal_response_to1.19832471
69MP0002006_tumorigenesis1.19369634
70MP0002277_abnormal_respiratory_mucosa1.19233431
71MP0010307_abnormal_tumor_latency1.14439819
72MP0005084_abnormal_gallbladder_morpholo1.11401068
73MP0000703_abnormal_thymus_morphology1.11335539
74MP0000015_abnormal_ear_pigmentation1.10679727
75MP0004381_abnormal_hair_follicle1.08818307
76MP0003763_abnormal_thymus_physiology1.04560265
77MP0005390_skeleton_phenotype0.99279788
78MP0000490_abnormal_crypts_of0.95519763
79MP0010352_gastrointestinal_tract_polyps0.94242141
80MP0002009_preneoplasia0.90771091
81MP0002928_abnormal_bile_duct0.90164861
82MP0009333_abnormal_splenocyte_physiolog0.89213451
83MP0009763_increased_sensitivity_to0.84796585
84MP0001663_abnormal_digestive_system0.83588310
85MP0003279_aneurysm0.83148536
86MP0000249_abnormal_blood_vessel0.83085072
87MP0005310_abnormal_salivary_gland0.82530497
88MP0003866_abnormal_defecation0.77956879
89MP0005166_decreased_susceptibility_to0.76684346
90MP0001958_emphysema0.76031141
91MP0009765_abnormal_xenobiotic_induced0.75906508
92MP0002019_abnormal_tumor_incidence0.74714650
93MP0005377_hearing/vestibular/ear_phenot0.74307191
94MP0003878_abnormal_ear_physiology0.74307191
95MP0003690_abnormal_glial_cell0.72845370
96MP0005083_abnormal_biliary_tract0.68809844
97MP0003638_abnormal_response/metabolism_0.68436918
98MP0002877_abnormal_melanocyte_morpholog0.67286673
99MP0000604_amyloidosis0.67249654
100MP0009840_abnormal_foam_cell0.67087196
101MP0008057_abnormal_DNA_replication0.66570396
102MP0005319_abnormal_enzyme/_coenzyme0.66397923
103MP0004264_abnormal_extraembryonic_tissu0.65994066
104MP0002095_abnormal_skin_pigmentation0.65615561
105MP0003693_abnormal_embryo_hatching0.65350736
106MP0003795_abnormal_bone_structure0.65058091
107MP0003453_abnormal_keratinocyte_physiol0.64338868
108MP0002138_abnormal_hepatobiliary_system0.63438671
109MP0006082_CNS_inflammation0.62161624
110MP0008004_abnormal_stomach_pH0.61735638
111MP0002693_abnormal_pancreas_physiology0.60913288
112MP0004130_abnormal_muscle_cell0.59484274
113MP0005535_abnormal_body_temperature0.59351377
114MP0002133_abnormal_respiratory_system0.57669974
115MP0005388_respiratory_system_phenotype0.57669974
116MP0000609_abnormal_liver_physiology0.54160376
117MP0002998_abnormal_bone_remodeling0.53706255
118MP0003111_abnormal_nucleus_morphology0.52207167
119MP0008873_increased_physiological_sensi0.51327442
120MP0003045_fibrosis0.51234907
121MP0005381_digestive/alimentary_phenotyp0.47310876

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)8.83067332
2Recurrent abscess formation (HP:0002722)8.49311464
3Recurrent gram-negative bacterial infections (HP:0005420)7.76462683
4Recurrent bacterial skin infections (HP:0005406)7.60200090
5Chronic obstructive pulmonary disease (HP:0006510)5.78442742
6Obstructive lung disease (HP:0006536)5.78442742
7Gingivitis (HP:0000230)5.22255272
8Abnormality of macrophages (HP:0004311)5.21848824
9Mediastinal lymphadenopathy (HP:0100721)5.19580842
10Recurrent fungal infections (HP:0002841)4.84196991
11Recurrent skin infections (HP:0001581)4.63525535
12Myositis (HP:0100614)4.50483579
13Stomatitis (HP:0010280)4.38566343
14Cellulitis (HP:0100658)4.15807484
15Urticaria (HP:0001025)4.07611192
16Hypochromic microcytic anemia (HP:0004840)4.00709767
17Meningitis (HP:0001287)3.90230481
18Orchitis (HP:0100796)3.80210537
19Panhypogammaglobulinemia (HP:0003139)3.51781123
20Periodontitis (HP:0000704)3.40123458
21Retrobulbar optic neuritis (HP:0100654)3.40028268
22Optic neuritis (HP:0100653)3.40028268
23IgM deficiency (HP:0002850)3.39710226
24Spontaneous hematomas (HP:0007420)3.06892444
25Episodic fever (HP:0001954)3.05383057
26Recurrent cutaneous fungal infections (HP:0011370)3.00699651
27Chronic mucocutaneous candidiasis (HP:0002728)3.00699651
28Agammaglobulinemia (HP:0004432)2.99895466
29Keratoconjunctivitis sicca (HP:0001097)2.94188204
30Osteomyelitis (HP:0002754)2.90142654
31Recurrent viral infections (HP:0004429)2.80009415
32Vasculitis (HP:0002633)2.70572356
33Abnormality of T cells (HP:0002843)2.68606753
34Abnormal platelet volume (HP:0011876)2.67448566
35Leukocytosis (HP:0001974)2.67119116
36Increased IgM level (HP:0003496)2.65833645
37Abnormality of the heme biosynthetic pathway (HP:0010472)2.65510396
38Hemoptysis (HP:0002105)2.63817933
39Keratoconjunctivitis (HP:0001096)2.63806355
40Sepsis (HP:0100806)2.60672757
41Amyloidosis (HP:0011034)2.59567558
42Abnormal delayed hypersensitivity skin test (HP:0002963)2.58422712
43Epistaxis (HP:0000421)2.57973458
44Microcytic anemia (HP:0001935)2.57919138
45Elevated erythrocyte sedimentation rate (HP:0003565)2.57665044
46Papilledema (HP:0001085)2.53452874
47Anorexia (HP:0002039)2.53227874
48Recurrent pneumonia (HP:0006532)2.52134418
49Hypergammaglobulinemia (HP:0010702)2.50191179
50Chest pain (HP:0100749)2.50128212
51Gingival bleeding (HP:0000225)2.49944652
52Prolonged bleeding time (HP:0003010)2.49293656
53Abnormality of glycolipid metabolism (HP:0010969)2.47686830
54Abnormality of liposaccharide metabolism (HP:0010968)2.47686830
55Abnormality of glycosphingolipid metabolism (HP:0004343)2.47686830
56Arterial thrombosis (HP:0004420)2.46999876
57Pustule (HP:0200039)2.43118734
58Thyroiditis (HP:0100646)2.41867677
59Abnormality of iron homeostasis (HP:0011031)2.41352436
60Absent frontal sinuses (HP:0002688)2.41086306
61Increased IgE level (HP:0003212)2.40236481
62Eosinophilia (HP:0001880)2.37866476
63Increased serum ferritin (HP:0003281)2.36920120
64Skin ulcer (HP:0200042)2.36639055
65Increased density of long bones (HP:0006392)2.36059599
66Absent rod-and cone-mediated responses on ERG (HP:0007688)2.35446545
67Petechiae (HP:0000967)2.35395695
68Thickened calvaria (HP:0002684)2.34078935
69Hepatosplenomegaly (HP:0001433)2.32719829
70Pulmonary infiltrates (HP:0002113)2.30662441
71Abnormality of T cell number (HP:0011839)2.28892664
72Cheilitis (HP:0100825)2.26588545
73Interstitial pulmonary disease (HP:0006530)2.23609102
74Vacuolated lymphocytes (HP:0001922)2.20352662
75Pulmonary embolism (HP:0002204)2.18453909
76T lymphocytopenia (HP:0005403)2.18150517
77Inflammation of the large intestine (HP:0002037)2.15650521
78Abnormality of transition element cation homeostasis (HP:0011030)2.15531368
79Gastrointestinal inflammation (HP:0004386)2.14207533
80Granulocytopenia (HP:0001913)2.14136994
81Colitis (HP:0002583)2.12970933
82Impaired platelet aggregation (HP:0003540)2.11251153
83Abnormal platelet function (HP:0011869)2.11251153
84Purpura (HP:0000979)2.11001869
85Increased mean platelet volume (HP:0011877)2.07743741
86Systemic lupus erythematosus (HP:0002725)2.07126095
87Encephalitis (HP:0002383)2.05945848
88Skin rash (HP:0000988)2.05708427
89Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.03990549
90Vertigo (HP:0002321)2.02507097
91Recurrent lower respiratory tract infections (HP:0002783)2.02475506
92Abnormality of eosinophils (HP:0001879)2.02433331
93Peritonitis (HP:0002586)1.99639165
94Thoracic kyphosis (HP:0002942)1.99635753
95Gastrointestinal infarctions (HP:0005244)1.99557350
96Menorrhagia (HP:0000132)1.96371599
97Abnormality of B cell number (HP:0010975)1.94042696
98B lymphocytopenia (HP:0010976)1.94042696
99Autoimmune thrombocytopenia (HP:0001973)1.93851508
100Autoimmune hemolytic anemia (HP:0001890)1.90463505
101Loss of speech (HP:0002371)1.88496860
102Polyneuropathy (HP:0001271)1.88158474
103Abnormal rod and cone electroretinograms (HP:0008323)1.87898695
104Spinal cord lesions (HP:0100561)1.85034422
105Syringomyelia (HP:0003396)1.85034422
106Abnormality of the thoracic spine (HP:0100711)1.84881106
107Acute hepatic failure (HP:0006554)1.84727659
108Viral hepatitis (HP:0006562)1.83524342
109Abnormality of T cell physiology (HP:0011840)1.82185521
110Gangrene (HP:0100758)1.81812667
111Chronic otitis media (HP:0000389)1.81097889
112Papilloma (HP:0012740)1.79382964
113Verrucae (HP:0200043)1.79382964
114Persistence of primary teeth (HP:0006335)1.79327090
115Abnormality of the pleura (HP:0002103)1.78714894
116Increased cerebral lipofuscin (HP:0011813)1.77980500
117Thrombocytosis (HP:0001894)1.77718973
118Abnormal foot bone ossification (HP:0010675)1.76522983
119Hypermelanotic macule (HP:0001034)1.76091584
120Abnormality of cells of the lymphoid lineage (HP:0012140)1.74892183
121Lymphopenia (HP:0001888)1.74665759
122Dysostosis multiplex (HP:0000943)1.73429523
123Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.72483040
124Hypochromic anemia (HP:0001931)1.70981189
125Cutaneous photosensitivity (HP:0000992)1.68081341
126Abnormality of the prostate (HP:0008775)1.67753093
127Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.66723167
128Myelodysplasia (HP:0002863)1.66654828
129Abnormality of the endocardium (HP:0004306)1.65934515
130Increased neuronal autofluorescent lipopigment (HP:0002074)1.64865892
131Spondylolisthesis (HP:0003302)1.63943951
132Agnosia (HP:0010524)1.63228500

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK44.88255341
2EPHB13.88754488
3MAP4K12.89065726
4FES2.76033296
5RIPK42.60550188
6GRK62.53408742
7BTK2.49232894
8CSK2.48506153
9ERN12.42921345
10BLK2.33537076
11TXK2.29457811
12STK102.23675057
13TRPM72.21292717
14MAP2K32.13023175
15TAOK32.08788097
16CLK12.05145690
17HCK1.99262124
18TESK21.83033211
19TEC1.82051373
20TYK21.80342781
21TTN1.78584782
22FGR1.78314671
23CDK121.74948697
24IRAK31.71707008
25ZAP701.62816628
26PRPF4B1.52202806
27BCKDK1.50150941
28PAK41.40776237
29TRIB31.34863167
30PTK61.32322837
31LRRK21.31262629
32ERBB31.30303926
33MAP3K91.30117342
34SYK1.27270673
35MAP3K141.21000978
36CDK191.18158412
37ITK1.15306961
38ALK1.12422480
39BMPR21.11513944
40MAP3K121.09904256
41PIM11.07392336
42JAK11.05090710
43SIK21.03151249
44NEK21.02286055
45TGFBR20.96407738
46TAOK10.95523195
47CSF1R0.94523326
48PKN20.90881297
49PRKG20.90786359
50GRK70.89781198
51PRKD20.89113176
52TESK10.88341009
53LYN0.87975856
54FLT30.86767313
55MAPK40.85255849
56JAK20.84190622
57SIK30.83730970
58CAMK1D0.83355048
59TBK10.82884520
60LCK0.82354541
61STK40.81269104
62CAMK1G0.80368145
63KIT0.79733771
64MARK20.79400918
65MARK30.79267978
66MAPK120.77959825
67TNK20.77901384
68IRAK10.77357039
69MAP3K80.77242590
70IKBKE0.76674142
71PRKCQ0.74254522
72MAP2K60.72715158
73KDR0.71569084
74MAP3K30.70906034
75DMPK0.70752698
76FGFR30.70726748
77JAK30.66924736
78MAP2K40.66047480
79PTK20.65575718
80MAPK70.65001119
81MAP3K110.64976380
82DAPK20.64671419
83MAP3K130.62233064
84MAP3K70.61852301
85EEF2K0.59209363
86IRAK20.57195472
87MAP2K20.56297461
88PTK2B0.56261049
89RPS6KA60.55386180
90RIPK10.55282244
91RPS6KL10.55035297
92RPS6KC10.55035297
93HIPK20.54812570
94MATK0.51951011
95RPS6KA20.51040592
96FRK0.50475557
97YES10.49412557
98FYN0.49407377
99MAPKAPK20.48747129
100KSR20.48485664
101PIK3CG0.47835858
102TAOK20.46961353
103SGK30.45168962
104CDK40.44675580
105CDK60.44585049
106MAP3K60.43905638
107IKBKB0.43702623
108CDC70.42398366
109PRKCD0.41759729
110MAPK110.41563967
111STK110.40630813
112EPHA30.40214465
113DYRK1B0.39708264
114ABL10.39185060
115PDPK10.38793614
116MOS0.38673900
117PRKCH0.37889343
118MAP3K10.37847245
119PRKAA20.37636214
120STK240.37358809
121ADRBK20.36649453
122PDK10.36144185
123CDK70.35919686
124MAP3K50.35615620
125MAP4K20.33677374
126CAMKK20.33043122
127ADRBK10.31956855
128TLK10.28250860
129PINK10.27464124
130RPS6KA10.24729540
131MAPK30.23761392

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.93509165
2Staphylococcus aureus infection_Homo sapiens_hsa051503.00414316
3Osteoclast differentiation_Homo sapiens_hsa043802.88269469
4Allograft rejection_Homo sapiens_hsa053302.81146250
5Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.74289514
6Graft-versus-host disease_Homo sapiens_hsa053322.74029347
7Leukocyte transendothelial migration_Homo sapiens_hsa046702.66910616
8Autoimmune thyroid disease_Homo sapiens_hsa053202.56488156
9Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.43896240
10Asthma_Homo sapiens_hsa053102.26273352
11B cell receptor signaling pathway_Homo sapiens_hsa046622.21406999
12Type I diabetes mellitus_Homo sapiens_hsa049402.18464824
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.96643615
14Chemokine signaling pathway_Homo sapiens_hsa040621.91777277
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.89877979
16Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.88399480
17Tuberculosis_Homo sapiens_hsa051521.82100313
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.77000801
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.74175138
20Caffeine metabolism_Homo sapiens_hsa002321.74006276
21Shigellosis_Homo sapiens_hsa051311.72162783
22Pertussis_Homo sapiens_hsa051331.67264561
23Hematopoietic cell lineage_Homo sapiens_hsa046401.66739917
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.57798366
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.56608343
26Acute myeloid leukemia_Homo sapiens_hsa052211.47849475
27Platelet activation_Homo sapiens_hsa046111.46374446
28Toxoplasmosis_Homo sapiens_hsa051451.44337928
29Rheumatoid arthritis_Homo sapiens_hsa053231.39930091
30Jak-STAT signaling pathway_Homo sapiens_hsa046301.39090668
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.38432100
32Measles_Homo sapiens_hsa051621.37184383
33Neurotrophin signaling pathway_Homo sapiens_hsa047221.35721677
34Pentose phosphate pathway_Homo sapiens_hsa000301.34859500
35Legionellosis_Homo sapiens_hsa051341.32887594
36TNF signaling pathway_Homo sapiens_hsa046681.31930175
37Hepatitis B_Homo sapiens_hsa051611.27533364
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.25953522
39Pancreatic cancer_Homo sapiens_hsa052121.24651700
40VEGF signaling pathway_Homo sapiens_hsa043701.24603822
41Salmonella infection_Homo sapiens_hsa051321.23219544
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.18595061
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.18501529
44Other glycan degradation_Homo sapiens_hsa005111.18032478
45Chronic myeloid leukemia_Homo sapiens_hsa052201.16032385
46T cell receptor signaling pathway_Homo sapiens_hsa046601.13187468
47Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12236049
48Influenza A_Homo sapiens_hsa051641.12083747
49Phagosome_Homo sapiens_hsa041451.11751935
50Non-small cell lung cancer_Homo sapiens_hsa052231.04638444
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.03831503
52Regulation of autophagy_Homo sapiens_hsa041401.02947808
53Viral myocarditis_Homo sapiens_hsa054161.02153567
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01397094
55Apoptosis_Homo sapiens_hsa042101.01251032
56Glycosaminoglycan degradation_Homo sapiens_hsa005311.00992553
57Malaria_Homo sapiens_hsa051440.97929408
58Herpes simplex infection_Homo sapiens_hsa051680.97441367
59Primary immunodeficiency_Homo sapiens_hsa053400.97427471
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95829872
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.95323791
62Insulin resistance_Homo sapiens_hsa049310.93636069
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.88136286
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87123622
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86698853
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.85794384
67Amoebiasis_Homo sapiens_hsa051460.85017002
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.82226656
69Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79121578
70Starch and sucrose metabolism_Homo sapiens_hsa005000.75871799
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.74875689
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71230892
73Bladder cancer_Homo sapiens_hsa052190.69394469
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.69259632
75Prolactin signaling pathway_Homo sapiens_hsa049170.67291904
76Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.67122790
77Hepatitis C_Homo sapiens_hsa051600.66880797
78Lysosome_Homo sapiens_hsa041420.64822776
79Type II diabetes mellitus_Homo sapiens_hsa049300.64242256
80Proteoglycans in cancer_Homo sapiens_hsa052050.64212686
81Endocytosis_Homo sapiens_hsa041440.62108287
82Viral carcinogenesis_Homo sapiens_hsa052030.61599551
83Complement and coagulation cascades_Homo sapiens_hsa046100.60136598
84Collecting duct acid secretion_Homo sapiens_hsa049660.59626860
85Epstein-Barr virus infection_Homo sapiens_hsa051690.59399541
86ABC transporters_Homo sapiens_hsa020100.58862720
87mTOR signaling pathway_Homo sapiens_hsa041500.58838586
88MicroRNAs in cancer_Homo sapiens_hsa052060.57686571
89FoxO signaling pathway_Homo sapiens_hsa040680.54902106
90Estrogen signaling pathway_Homo sapiens_hsa049150.54426566
91Colorectal cancer_Homo sapiens_hsa052100.54127329
92Rap1 signaling pathway_Homo sapiens_hsa040150.54095134
93Arachidonic acid metabolism_Homo sapiens_hsa005900.53777824
94HIF-1 signaling pathway_Homo sapiens_hsa040660.52151844
95Lysine degradation_Homo sapiens_hsa003100.51936545
96Inositol phosphate metabolism_Homo sapiens_hsa005620.51394624
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.50434200
98Antigen processing and presentation_Homo sapiens_hsa046120.50002924
99Small cell lung cancer_Homo sapiens_hsa052220.49781515
100MAPK signaling pathway_Homo sapiens_hsa040100.49089020
101HTLV-I infection_Homo sapiens_hsa051660.48703530
102Glioma_Homo sapiens_hsa052140.47470373
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47032353
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47002830
105Dorso-ventral axis formation_Homo sapiens_hsa043200.45163267
106Insulin signaling pathway_Homo sapiens_hsa049100.45129916
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44461219
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44191508
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.43604540
110Choline metabolism in cancer_Homo sapiens_hsa052310.42893995
111Histidine metabolism_Homo sapiens_hsa003400.41662450
112Renal cell carcinoma_Homo sapiens_hsa052110.41396524
113Adipocytokine signaling pathway_Homo sapiens_hsa049200.40353882
114Focal adhesion_Homo sapiens_hsa045100.40245008
115DNA replication_Homo sapiens_hsa030300.38992277
116Ether lipid metabolism_Homo sapiens_hsa005650.38912027
117African trypanosomiasis_Homo sapiens_hsa051430.38379805
118Notch signaling pathway_Homo sapiens_hsa043300.38313009
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.37203770
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36912510
121GnRH signaling pathway_Homo sapiens_hsa049120.35947322
122p53 signaling pathway_Homo sapiens_hsa041150.34560909
123Cell cycle_Homo sapiens_hsa041100.34438208
124Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34356033
125Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33733974
126Linoleic acid metabolism_Homo sapiens_hsa005910.27499524
127Systemic lupus erythematosus_Homo sapiens_hsa053220.23478787
128Olfactory transduction_Homo sapiens_hsa047400.23261043

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