Rank | Gene Set | Z-score |
---|---|---|
1 | pre-miRNA processing (GO:0031054) | 4.87517661 |
2 | Golgi transport vesicle coating (GO:0048200) | 4.69170101 |
3 | COPI coating of Golgi vesicle (GO:0048205) | 4.69170101 |
4 | regulation of translational fidelity (GO:0006450) | 4.62202619 |
5 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.55546335 |
6 | regulation of gene silencing by RNA (GO:0060966) | 4.37504470 |
7 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.37504470 |
8 | regulation of gene silencing by miRNA (GO:0060964) | 4.37504470 |
9 | heterochromatin organization (GO:0070828) | 4.34676696 |
10 | proline biosynthetic process (GO:0006561) | 4.11167067 |
11 | regulation of hippo signaling (GO:0035330) | 4.05690432 |
12 | DNA unwinding involved in DNA replication (GO:0006268) | 4.03941399 |
13 | establishment of apical/basal cell polarity (GO:0035089) | 3.96443749 |
14 | regulation of translational termination (GO:0006449) | 3.95149923 |
15 | nuclear pore organization (GO:0006999) | 3.88603997 |
16 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.83316002 |
17 | protein localization to kinetochore (GO:0034501) | 3.78797903 |
18 | nuclear pore complex assembly (GO:0051292) | 3.78735214 |
19 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.77623669 |
20 | maternal placenta development (GO:0001893) | 3.71795663 |
21 | negative regulation of cell size (GO:0045792) | 3.63492215 |
22 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.62762357 |
23 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.60269230 |
24 | apoptotic process involved in morphogenesis (GO:0060561) | 3.59061684 |
25 | mitotic nuclear envelope reassembly (GO:0007084) | 3.56741005 |
26 | nuclear envelope reassembly (GO:0031468) | 3.56741005 |
27 | regulation of RNA export from nucleus (GO:0046831) | 3.54938992 |
28 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.50276086 |
29 | polarized epithelial cell differentiation (GO:0030859) | 3.48397358 |
30 | negative regulation of histone methylation (GO:0031061) | 3.47280615 |
31 | mitotic nuclear envelope disassembly (GO:0007077) | 3.44657150 |
32 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.44423524 |
33 | chromatin assembly (GO:0031497) | 3.41067064 |
34 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.40493264 |
35 | mRNA stabilization (GO:0048255) | 3.38292425 |
36 | RNA stabilization (GO:0043489) | 3.38292425 |
37 | protein complex localization (GO:0031503) | 3.34307618 |
38 | establishment of monopolar cell polarity (GO:0061162) | 3.32486278 |
39 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 3.32486278 |
40 | trophectodermal cell differentiation (GO:0001829) | 3.31698288 |
41 | nuclear envelope disassembly (GO:0051081) | 3.31204624 |
42 | membrane disassembly (GO:0030397) | 3.31204624 |
43 | mitotic G1/S transition checkpoint (GO:0044819) | 3.31154056 |
44 | sister chromatid segregation (GO:0000819) | 3.29932636 |
45 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.27944354 |
46 | dosage compensation (GO:0007549) | 3.27763804 |
47 | mitotic sister chromatid segregation (GO:0000070) | 3.26773197 |
48 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.25580603 |
49 | G1 DNA damage checkpoint (GO:0044783) | 3.24438303 |
50 | paraxial mesoderm development (GO:0048339) | 3.24114031 |
51 | protein retention in ER lumen (GO:0006621) | 3.23464196 |
52 | formation of translation preinitiation complex (GO:0001731) | 3.20223043 |
53 | pentose-phosphate shunt (GO:0006098) | 3.18841110 |
54 | peptidyl-lysine dimethylation (GO:0018027) | 3.17755690 |
55 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.16030636 |
56 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.16027794 |
57 | NLS-bearing protein import into nucleus (GO:0006607) | 3.15925492 |
58 | peptidyl-arginine methylation (GO:0018216) | 3.15348617 |
59 | peptidyl-arginine N-methylation (GO:0035246) | 3.15348617 |
60 | DNA strand elongation (GO:0022616) | 3.14123242 |
61 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 3.12587181 |
62 | establishment of integrated proviral latency (GO:0075713) | 3.09891498 |
63 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.08160985 |
64 | protein localization to chromosome, centromeric region (GO:0071459) | 3.04694814 |
65 | regulation of sister chromatid cohesion (GO:0007063) | 3.04538482 |
66 | cellular protein complex localization (GO:0034629) | 3.02920897 |
67 | positive regulation of chromosome segregation (GO:0051984) | 3.02165589 |
68 | positive regulation of histone deacetylation (GO:0031065) | 3.01954877 |
69 | regulation of SMAD protein import into nucleus (GO:0060390) | 3.00021674 |
70 | DNA replication initiation (GO:0006270) | 2.97881541 |
71 | adherens junction assembly (GO:0034333) | 2.97441192 |
72 | histone H2A monoubiquitination (GO:0035518) | 2.97313268 |
73 | protein maturation by protein folding (GO:0022417) | 2.96120761 |
74 | DNA duplex unwinding (GO:0032508) | 2.95596468 |
75 | rRNA transcription (GO:0009303) | 2.94820211 |
76 | negative regulation of mRNA processing (GO:0050686) | 2.94752936 |
77 | mitotic chromosome condensation (GO:0007076) | 2.94146012 |
78 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.94079318 |
79 | mitotic metaphase plate congression (GO:0007080) | 2.92174007 |
80 | nuclear envelope organization (GO:0006998) | 2.91055778 |
81 | DNA geometric change (GO:0032392) | 2.90988428 |
82 | regulation of histone H3-K9 methylation (GO:0051570) | 2.88084947 |
83 | negative regulation of RNA splicing (GO:0033119) | 2.87665644 |
84 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.85031623 |
85 | negative regulation of mRNA metabolic process (GO:1903312) | 2.84989832 |
86 | mitochondrial fusion (GO:0008053) | 2.84137658 |
87 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.83442466 |
88 | regulation of chromatin binding (GO:0035561) | 2.80479275 |
89 | snRNA metabolic process (GO:0016073) | 2.79204814 |
90 | GDP-mannose metabolic process (GO:0019673) | 2.77589879 |
91 | histone H4-K12 acetylation (GO:0043983) | 2.77214202 |
92 | cell-substrate adherens junction assembly (GO:0007045) | 2.76125837 |
93 | focal adhesion assembly (GO:0048041) | 2.76125837 |
94 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.76043902 |
95 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.76043902 |
96 | NADPH regeneration (GO:0006740) | 2.75581560 |
97 | chromatin silencing (GO:0006342) | 2.75244706 |
98 | establishment of viral latency (GO:0019043) | 2.74166848 |
99 | IMP biosynthetic process (GO:0006188) | 2.73868706 |
100 | negative regulation of glial cell proliferation (GO:0060253) | 2.73374715 |
101 | ribosome biogenesis (GO:0042254) | 2.73121599 |
102 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.72476113 |
103 | modulation by virus of host process (GO:0019054) | 2.72368396 |
104 | anterior/posterior axis specification, embryo (GO:0008595) | 2.71750708 |
105 | pore complex assembly (GO:0046931) | 2.71024848 |
106 | histone arginine methylation (GO:0034969) | 2.70564414 |
107 | proline metabolic process (GO:0006560) | 2.69571675 |
108 | positive regulation of RNA splicing (GO:0033120) | 2.66563033 |
109 | apoptotic process involved in development (GO:1902742) | 2.66443239 |
110 | ribosomal small subunit biogenesis (GO:0042274) | 2.66346993 |
111 | NIK/NF-kappaB signaling (GO:0038061) | 2.65812900 |
112 | regulation of mRNA stability (GO:0043488) | 2.64795323 |
113 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.64082615 |
114 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 2.61997139 |
115 | positive regulation of nuclease activity (GO:0032075) | 2.61397058 |
116 | hippo signaling (GO:0035329) | 2.60989667 |
117 | glucose catabolic process (GO:0006007) | 2.60977748 |
118 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.60896576 |
119 | protein export from nucleus (GO:0006611) | 2.60638090 |
120 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.58702196 |
121 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.58307673 |
122 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.58276428 |
123 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.58276428 |
124 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.58276428 |
125 | gene silencing (GO:0016458) | 2.57981052 |
126 | NADH metabolic process (GO:0006734) | 2.57767576 |
127 | activation of Rac GTPase activity (GO:0032863) | 2.57707330 |
128 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.57548959 |
129 | modulation by symbiont of host cellular process (GO:0044068) | 2.57399571 |
130 | DNA topological change (GO:0006265) | 2.57294520 |
131 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.55776165 |
132 | mRNA splicing, via spliceosome (GO:0000398) | 2.55614167 |
133 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.55614167 |
134 | glucose 6-phosphate metabolic process (GO:0051156) | 2.55386185 |
135 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.54681174 |
136 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.53816307 |
137 | folic acid metabolic process (GO:0046655) | 2.52895386 |
138 | regulation of translational elongation (GO:0006448) | 2.52101117 |
139 | regulation of early endosome to late endosome transport (GO:2000641) | 2.51675162 |
140 | embryonic process involved in female pregnancy (GO:0060136) | 2.51454853 |
141 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.50673509 |
142 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.50673509 |
143 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.49740773 |
144 | protein localization to endosome (GO:0036010) | 2.49095206 |
145 | protein-DNA complex disassembly (GO:0032986) | 2.48457544 |
146 | nucleosome disassembly (GO:0006337) | 2.48457544 |
147 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.48316753 |
148 | negative regulation of nucleotide catabolic process (GO:0030812) | 2.47952880 |
149 | RNA splicing, via transesterification reactions (GO:0000375) | 2.47847350 |
150 | negative regulation of viral release from host cell (GO:1902187) | 2.47793145 |
151 | cellular hyperosmotic response (GO:0071474) | 2.47557396 |
152 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.46691053 |
153 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.46380613 |
154 | regulation of RNA stability (GO:0043487) | 2.45461029 |
155 | regulation of gene silencing (GO:0060968) | 2.45200333 |
156 | chromosome condensation (GO:0030261) | 2.44694650 |
157 | pentose metabolic process (GO:0019321) | 2.41886447 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.27608234 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.39159419 |
3 | * MYC_22102868_ChIP-Seq_BL_Human | 3.31081018 |
4 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.87025051 |
5 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.75832218 |
6 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.75539452 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.63149135 |
8 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.35384642 |
9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.30007169 |
10 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.19765206 |
11 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.16324028 |
12 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.11128500 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.09707243 |
14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.08841912 |
15 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.07672250 |
16 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.97955548 |
17 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.95632597 |
18 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.95365743 |
19 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.93962120 |
20 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.92671403 |
21 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.88187093 |
22 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.86583711 |
23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.85612516 |
24 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.84686684 |
25 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.82217078 |
26 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.81049189 |
27 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.73571905 |
28 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.71876051 |
29 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.64464328 |
30 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.63099553 |
31 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62652224 |
32 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.62591282 |
33 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.62322810 |
34 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.58034127 |
35 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.57454154 |
36 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.56411015 |
37 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.55422217 |
38 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.53677662 |
39 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.53023543 |
40 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.51921879 |
41 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.51581299 |
42 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.50222154 |
43 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.48720574 |
44 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.48658958 |
45 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.46388594 |
46 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.46388594 |
47 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.46388594 |
48 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.46308316 |
49 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.45995378 |
50 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.45913069 |
51 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.45001414 |
52 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.44076349 |
53 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.44065432 |
54 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.43318936 |
55 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.43285379 |
56 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.41452199 |
57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38365431 |
58 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.35823260 |
59 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.35200140 |
60 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.34838608 |
61 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.34294532 |
62 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.33642385 |
63 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.32300520 |
64 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.31716995 |
65 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.31299852 |
66 | * NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.30280279 |
67 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29284997 |
68 | UTX_26944678_Chip-Seq_JUKART_Human | 1.28590516 |
69 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.28242019 |
70 | MAF_26560356_Chip-Seq_TH1_Human | 1.27957184 |
71 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.27928914 |
72 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.26995168 |
73 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.25160564 |
74 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.24481088 |
75 | KDM2B_26808549_Chip-Seq_K562_Human | 1.24253717 |
76 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.24029639 |
77 | * NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.23907479 |
78 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.23720140 |
79 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.21686838 |
80 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21303571 |
81 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.19800463 |
82 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.19787589 |
83 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19711401 |
84 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.19665420 |
85 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.19637576 |
86 | * SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.19302743 |
87 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.18783442 |
88 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.18492543 |
89 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.18428128 |
90 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.18138877 |
91 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.17915062 |
92 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.17899180 |
93 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.17154657 |
94 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.16988762 |
95 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.16869450 |
96 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.16810895 |
97 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.16125488 |
98 | P68_20966046_ChIP-Seq_HELA_Human | 1.16077504 |
99 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.14106312 |
100 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.14080443 |
101 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.13847021 |
102 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.13527185 |
103 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.12635095 |
104 | * TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.12602233 |
105 | * POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.12065692 |
106 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.11486284 |
107 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.11086679 |
108 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.10107661 |
109 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.10051090 |
110 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.09798096 |
111 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.07742274 |
112 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07706102 |
113 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.07306487 |
114 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06966907 |
115 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.06072841 |
116 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.05623434 |
117 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05498708 |
118 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.05406671 |
119 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.04703314 |
120 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.03374039 |
121 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.03199656 |
122 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.01951575 |
123 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.01832239 |
124 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.00893930 |
125 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.00047226 |
126 | MAF_26560356_Chip-Seq_TH2_Human | 0.99809331 |
127 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.99718483 |
128 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.99092170 |
129 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.98694674 |
130 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.98599268 |
131 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.97806598 |
132 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96611626 |
133 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.95744173 |
134 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.95092634 |
135 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.94397162 |
136 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.94111682 |
137 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.93928121 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.44810482 |
2 | MP0005076_abnormal_cell_differentiation | 3.21326549 |
3 | MP0005451_abnormal_body_composition | 3.20448608 |
4 | MP0010352_gastrointestinal_tract_polyps | 3.12941126 |
5 | MP0003111_abnormal_nucleus_morphology | 2.66607027 |
6 | MP0004957_abnormal_blastocyst_morpholog | 2.55137200 |
7 | MP0008260_abnormal_autophagy | 2.45959414 |
8 | MP0001730_embryonic_growth_arrest | 2.40316706 |
9 | MP0005058_abnormal_lysosome_morphology | 2.24081810 |
10 | MP0003077_abnormal_cell_cycle | 2.17605700 |
11 | MP0009278_abnormal_bone_marrow | 2.13210778 |
12 | MP0004197_abnormal_fetal_growth/weight/ | 2.13078510 |
13 | MP0004185_abnormal_adipocyte_glucose | 2.11155665 |
14 | MP0010030_abnormal_orbit_morphology | 2.10339997 |
15 | MP0010307_abnormal_tumor_latency | 2.02659667 |
16 | MP0000537_abnormal_urethra_morphology | 1.99561016 |
17 | MP0003123_paternal_imprinting | 1.99354456 |
18 | MP0003693_abnormal_embryo_hatching | 1.98068787 |
19 | MP0001672_abnormal_embryogenesis/_devel | 1.97933623 |
20 | MP0005380_embryogenesis_phenotype | 1.97933623 |
21 | MP0002084_abnormal_developmental_patter | 1.97025541 |
22 | MP0000678_abnormal_parathyroid_gland | 1.94541786 |
23 | MP0000350_abnormal_cell_proliferation | 1.94359273 |
24 | MP0003984_embryonic_growth_retardation | 1.91776301 |
25 | MP0010234_abnormal_vibrissa_follicle | 1.91142232 |
26 | MP0002088_abnormal_embryonic_growth/wei | 1.90014835 |
27 | MP0002086_abnormal_extraembryonic_tissu | 1.86590975 |
28 | MP0001849_ear_inflammation | 1.85902576 |
29 | MP0003283_abnormal_digestive_organ | 1.84201974 |
30 | MP0004233_abnormal_muscle_weight | 1.83735130 |
31 | MP0009053_abnormal_anal_canal | 1.83197452 |
32 | MP0010094_abnormal_chromosome_stability | 1.83177414 |
33 | MP0001697_abnormal_embryo_size | 1.83091945 |
34 | MP0008057_abnormal_DNA_replication | 1.81458274 |
35 | MP0002653_abnormal_ependyma_morphology | 1.80205885 |
36 | MP0002085_abnormal_embryonic_tissue | 1.79178502 |
37 | MP0000733_abnormal_muscle_development | 1.78246332 |
38 | MP0003119_abnormal_digestive_system | 1.77915835 |
39 | MP0002796_impaired_skin_barrier | 1.77759902 |
40 | MP0003566_abnormal_cell_adhesion | 1.75305455 |
41 | MP0009333_abnormal_splenocyte_physiolog | 1.73858861 |
42 | MP0002080_prenatal_lethality | 1.62781817 |
43 | MP0002249_abnormal_larynx_morphology | 1.55089133 |
44 | MP0008961_abnormal_basal_metabolism | 1.53919475 |
45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.49571839 |
46 | MP0002269_muscular_atrophy | 1.40947450 |
47 | MP0009840_abnormal_foam_cell | 1.40858455 |
48 | MP0008058_abnormal_DNA_repair | 1.40429800 |
49 | MP0002877_abnormal_melanocyte_morpholog | 1.37484910 |
50 | MP0010630_abnormal_cardiac_muscle | 1.37094035 |
51 | MP0001346_abnormal_lacrimal_gland | 1.36968908 |
52 | MP0004087_abnormal_muscle_fiber | 1.36308762 |
53 | MP0003303_peritoneal_inflammation | 1.34795310 |
54 | MP0005623_abnormal_meninges_morphology | 1.33802320 |
55 | MP0000747_muscle_weakness | 1.33553924 |
56 | MP0003890_abnormal_embryonic-extraembry | 1.32994616 |
57 | MP0003115_abnormal_respiratory_system | 1.32367406 |
58 | MP0000750_abnormal_muscle_regeneration | 1.30509248 |
59 | MP0000428_abnormal_craniofacial_morphol | 1.27896139 |
60 | MP0001293_anophthalmia | 1.27393579 |
61 | MP0009672_abnormal_birth_weight | 1.26365711 |
62 | MP0003221_abnormal_cardiomyocyte_apopto | 1.22587678 |
63 | MP0005666_abnormal_adipose_tissue | 1.22333086 |
64 | MP0004084_abnormal_cardiac_muscle | 1.21338492 |
65 | MP0002925_abnormal_cardiovascular_devel | 1.14330362 |
66 | MP0000858_altered_metastatic_potential | 1.12466558 |
67 | MP0008770_decreased_survivor_rate | 1.12221364 |
68 | MP0005023_abnormal_wound_healing | 1.11706866 |
69 | MP0003300_gastrointestinal_ulcer | 1.10850948 |
70 | MP0002092_abnormal_eye_morphology | 1.10640378 |
71 | MP0009703_decreased_birth_body | 1.08815567 |
72 | MP0002697_abnormal_eye_size | 1.05164008 |
73 | MP0000751_myopathy | 1.04836747 |
74 | MP0005375_adipose_tissue_phenotype | 1.04328573 |
75 | MP0005397_hematopoietic_system_phenotyp | 1.03572782 |
76 | MP0001545_abnormal_hematopoietic_system | 1.03572782 |
77 | MP0000266_abnormal_heart_morphology | 1.02738796 |
78 | MP0003436_decreased_susceptibility_to | 1.02477021 |
79 | MP0005330_cardiomyopathy | 1.01297941 |
80 | MP0003763_abnormal_thymus_physiology | 1.01166234 |
81 | MP0008932_abnormal_embryonic_tissue | 0.98701066 |
82 | MP0000759_abnormal_skeletal_muscle | 0.98625244 |
83 | MP0001915_intracranial_hemorrhage | 0.97654720 |
84 | MP0005384_cellular_phenotype | 0.97354027 |
85 | MP0002111_abnormal_tail_morphology | 0.94063302 |
86 | MP0004858_abnormal_nervous_system | 0.93412647 |
87 | MP0009931_abnormal_skin_appearance | 0.93345714 |
88 | MP0000313_abnormal_cell_death | 0.89888841 |
89 | MP0002089_abnormal_postnatal_growth/wei | 0.89787124 |
90 | MP0004130_abnormal_muscle_cell | 0.89246420 |
91 | MP0002019_abnormal_tumor_incidence | 0.88035796 |
92 | MP0000003_abnormal_adipose_tissue | 0.87801421 |
93 | MP0003315_abnormal_perineum_morphology | 0.87775047 |
94 | MP0004264_abnormal_extraembryonic_tissu | 0.87536031 |
95 | MP0002396_abnormal_hematopoietic_system | 0.87043148 |
96 | MP0008007_abnormal_cellular_replicative | 0.86988586 |
97 | MP0001661_extended_life_span | 0.86087954 |
98 | MP0003453_abnormal_keratinocyte_physiol | 0.84733344 |
99 | MP0000681_abnormal_thyroid_gland | 0.84546587 |
100 | MP0002106_abnormal_muscle_physiology | 0.84383956 |
101 | MP0001727_abnormal_embryo_implantation | 0.82892312 |
102 | MP0003935_abnormal_craniofacial_develop | 0.82374021 |
103 | MP0002398_abnormal_bone_marrow | 0.82250976 |
104 | MP0001784_abnormal_fluid_regulation | 0.81930893 |
105 | MP0000490_abnormal_crypts_of | 0.81609363 |
106 | MP0003861_abnormal_nervous_system | 0.80040828 |
107 | MP0003091_abnormal_cell_migration | 0.79537675 |
108 | MP0004510_myositis | 0.79440912 |
109 | MP0000358_abnormal_cell_content/ | 0.78930745 |
110 | MP0000534_abnormal_ureter_morphology | 0.78477205 |
111 | MP0004808_abnormal_hematopoietic_stem | 0.77693074 |
112 | MP0004947_skin_inflammation | 0.77435150 |
113 | MP0000467_abnormal_esophagus_morphology | 0.76879645 |
114 | MP0003942_abnormal_urinary_system | 0.75956729 |
115 | MP0003121_genomic_imprinting | 0.74897667 |
116 | MP0004133_heterotaxia | 0.74051047 |
117 | MP0000566_synostosis | 0.73337944 |
118 | MP0004145_abnormal_muscle_electrophysio | 0.72780940 |
119 | MP0003172_abnormal_lysosome_physiology | 0.72660559 |
120 | MP0002060_abnormal_skin_morphology | 0.72422183 |
121 | MP0002722_abnormal_immune_system | 0.71728896 |
122 | MP0003786_premature_aging | 0.71672686 |
123 | MP0005621_abnormal_cell_physiology | 0.68106179 |
124 | MP0001348_abnormal_lacrimal_gland | 0.68072739 |
125 | MP0000477_abnormal_intestine_morphology | 0.67805696 |
126 | MP0000703_abnormal_thymus_morphology | 0.67111042 |
127 | MP0003646_muscle_fatigue | 0.66309356 |
128 | MP0002429_abnormal_blood_cell | 0.66069398 |
129 | MP0002932_abnormal_joint_morphology | 0.65875368 |
130 | MP0001216_abnormal_epidermal_layer | 0.65097065 |
131 | MP0005501_abnormal_skin_physiology | 0.64541751 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cholecystitis (HP:0001082) | 3.75093159 |
2 | Abnormal gallbladder physiology (HP:0012438) | 3.75093159 |
3 | Ependymoma (HP:0002888) | 3.57160852 |
4 | Progressive muscle weakness (HP:0003323) | 3.43898695 |
5 | Abnormality of the lower motor neuron (HP:0002366) | 3.04948041 |
6 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.03708103 |
7 | Astrocytoma (HP:0009592) | 3.02273038 |
8 | Abnormality of the astrocytes (HP:0100707) | 3.02273038 |
9 | Ragged-red muscle fibers (HP:0003200) | 2.88848465 |
10 | Hyperacusis (HP:0010780) | 2.87882007 |
11 | Ulnar bowing (HP:0003031) | 2.81739310 |
12 | Distal lower limb amyotrophy (HP:0008944) | 2.81202176 |
13 | Long palpebral fissure (HP:0000637) | 2.79993592 |
14 | Cerebral aneurysm (HP:0004944) | 2.76238662 |
15 | Microvesicular hepatic steatosis (HP:0001414) | 2.73555305 |
16 | Difficulty climbing stairs (HP:0003551) | 2.62705918 |
17 | Broad distal phalanx of finger (HP:0009836) | 2.61473377 |
18 | Pseudobulbar signs (HP:0002200) | 2.57433797 |
19 | Increased connective tissue (HP:0009025) | 2.56837560 |
20 | Myopathic facies (HP:0002058) | 2.51400451 |
21 | Distal lower limb muscle weakness (HP:0009053) | 2.49619323 |
22 | Shallow orbits (HP:0000586) | 2.46557195 |
23 | Vertebral compression fractures (HP:0002953) | 2.46525877 |
24 | Exercise-induced muscle cramps (HP:0003710) | 2.45408288 |
25 | Angiofibromas (HP:0010615) | 2.45028480 |
26 | Adenoma sebaceum (HP:0009720) | 2.45028480 |
27 | Septate vagina (HP:0001153) | 2.43114260 |
28 | Short 4th metacarpal (HP:0010044) | 2.42159537 |
29 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.42159537 |
30 | Achilles tendon contracture (HP:0001771) | 2.39988674 |
31 | Upper limb amyotrophy (HP:0009129) | 2.39456562 |
32 | Distal upper limb amyotrophy (HP:0007149) | 2.39456562 |
33 | Genu recurvatum (HP:0002816) | 2.34663937 |
34 | Sparse lateral eyebrow (HP:0005338) | 2.34450198 |
35 | Multiple enchondromatosis (HP:0005701) | 2.33213940 |
36 | Hand muscle atrophy (HP:0009130) | 2.31829631 |
37 | Difficulty running (HP:0009046) | 2.29313281 |
38 | Metaphyseal cupping (HP:0003021) | 2.27094455 |
39 | Abnormality of the Achilles tendon (HP:0005109) | 2.26977529 |
40 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.24700361 |
41 | Abnormality of the 4th metacarpal (HP:0010012) | 2.24253660 |
42 | Increased nuchal translucency (HP:0010880) | 2.23902919 |
43 | Selective tooth agenesis (HP:0001592) | 2.23090945 |
44 | Abnormality of the umbilical cord (HP:0010881) | 2.21332122 |
45 | Hypercortisolism (HP:0001578) | 2.20093439 |
46 | Renal duplication (HP:0000075) | 2.19584917 |
47 | Fibroma (HP:0010614) | 2.18636306 |
48 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.16062615 |
49 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.16062615 |
50 | Single umbilical artery (HP:0001195) | 2.16062615 |
51 | Heterotopia (HP:0002282) | 2.15505160 |
52 | Neoplasm of striated muscle (HP:0009728) | 2.15486216 |
53 | Spastic diplegia (HP:0001264) | 2.14924568 |
54 | Rough bone trabeculation (HP:0100670) | 2.14898034 |
55 | Disproportionate tall stature (HP:0001519) | 2.13440102 |
56 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.12965323 |
57 | Hyperparathyroidism (HP:0000843) | 2.12704717 |
58 | Basal cell carcinoma (HP:0002671) | 2.12175931 |
59 | Insomnia (HP:0100785) | 2.09967918 |
60 | Glioma (HP:0009733) | 2.09929739 |
61 | Protrusio acetabuli (HP:0003179) | 2.09615422 |
62 | Fibrous tissue neoplasm (HP:0012316) | 2.09113148 |
63 | Lymphangioma (HP:0100764) | 2.08915940 |
64 | Progressive external ophthalmoplegia (HP:0000590) | 2.06633372 |
65 | Gastrointestinal carcinoma (HP:0002672) | 2.06380838 |
66 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.06380838 |
67 | Rectal prolapse (HP:0002035) | 2.05602458 |
68 | Hypertensive crisis (HP:0100735) | 2.04711452 |
69 | Truncus arteriosus (HP:0001660) | 2.02701468 |
70 | Ankle contracture (HP:0006466) | 2.01157752 |
71 | Broad thumb (HP:0011304) | 1.99218554 |
72 | Deviation of the thumb (HP:0009603) | 1.96889808 |
73 | Hyporeflexia of lower limbs (HP:0002600) | 1.96731484 |
74 | Testicular atrophy (HP:0000029) | 1.96108744 |
75 | Back pain (HP:0003418) | 1.95220763 |
76 | Rib fusion (HP:0000902) | 1.94920885 |
77 | Proximal placement of thumb (HP:0009623) | 1.93235604 |
78 | Shoulder girdle muscle weakness (HP:0003547) | 1.93103929 |
79 | EMG: neuropathic changes (HP:0003445) | 1.92993063 |
80 | Skin tags (HP:0010609) | 1.91779064 |
81 | Reticulocytosis (HP:0001923) | 1.91085684 |
82 | Muscle fiber splitting (HP:0003555) | 1.90560292 |
83 | Cholelithiasis (HP:0001081) | 1.90255639 |
84 | Subacute progressive viral hepatitis (HP:0006572) | 1.89877810 |
85 | Cellulitis (HP:0100658) | 1.89579457 |
86 | Broad face (HP:0000283) | 1.89010556 |
87 | Rhabdomyosarcoma (HP:0002859) | 1.88727875 |
88 | Mitral valve prolapse (HP:0001634) | 1.88698900 |
89 | Abnormality of the thoracic spine (HP:0100711) | 1.87212810 |
90 | Lower limb amyotrophy (HP:0007210) | 1.86703154 |
91 | Asymmetry of the thorax (HP:0001555) | 1.85733422 |
92 | Increased density of long bones (HP:0006392) | 1.84436999 |
93 | Turricephaly (HP:0000262) | 1.83118878 |
94 | Ulnar deviation of the wrist (HP:0003049) | 1.82243688 |
95 | Neoplasm of the oral cavity (HP:0100649) | 1.81724518 |
96 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.81293568 |
97 | Abnormality of the labia minora (HP:0012880) | 1.80633333 |
98 | Unilateral renal agenesis (HP:0000122) | 1.80308080 |
99 | Spinal muscular atrophy (HP:0007269) | 1.79816092 |
100 | Facial hemangioma (HP:0000329) | 1.79645707 |
101 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.77932563 |
102 | Abnormality of the calcaneus (HP:0008364) | 1.77903299 |
103 | Patellar dislocation (HP:0002999) | 1.76929007 |
104 | Obstructive sleep apnea (HP:0002870) | 1.76338636 |
105 | Dysmetric saccades (HP:0000641) | 1.76157849 |
106 | Elfin facies (HP:0004428) | 1.75567212 |
107 | Generalized amyotrophy (HP:0003700) | 1.74550604 |
108 | Annular pancreas (HP:0001734) | 1.74201465 |
109 | Biconcave vertebral bodies (HP:0004586) | 1.73884650 |
110 | Aneurysm (HP:0002617) | 1.73713578 |
111 | Enlarged penis (HP:0000040) | 1.73238304 |
112 | Renovascular hypertension (HP:0100817) | 1.73107046 |
113 | Pointed chin (HP:0000307) | 1.72951716 |
114 | Vertebral clefting (HP:0008428) | 1.71398247 |
115 | Short phalanx of the thumb (HP:0009660) | 1.71198212 |
116 | Abnormality of the gallbladder (HP:0005264) | 1.71143811 |
117 | Trismus (HP:0000211) | 1.71142341 |
118 | Pelvic girdle muscle weakness (HP:0003749) | 1.70186432 |
119 | Premature rupture of membranes (HP:0001788) | 1.70005929 |
120 | Biliary tract neoplasm (HP:0100574) | 1.68641160 |
121 | Missing ribs (HP:0000921) | 1.68138829 |
122 | Vertebral fusion (HP:0002948) | 1.68083239 |
123 | Stridor (HP:0010307) | 1.67871564 |
124 | Preauricular skin tag (HP:0000384) | 1.67627695 |
125 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.67603100 |
126 | Athetosis (HP:0002305) | 1.67445584 |
127 | Deep palmar crease (HP:0006191) | 1.67174563 |
128 | Bulbar palsy (HP:0001283) | 1.67141331 |
129 | Exercise-induced myalgia (HP:0003738) | 1.67086119 |
130 | Abnormality of the fingertips (HP:0001211) | 1.66670041 |
131 | Urethral obstruction (HP:0000796) | 1.66488473 |
132 | Increased variability in muscle fiber diameter (HP:0003557) | 1.66311264 |
133 | Short humerus (HP:0005792) | 1.66163294 |
134 | Breast hypoplasia (HP:0003187) | 1.65702250 |
135 | Overriding aorta (HP:0002623) | 1.65626828 |
136 | Fasciculations (HP:0002380) | 1.64536877 |
137 | Hallux valgus (HP:0001822) | 1.64219611 |
138 | Hypoparathyroidism (HP:0000829) | 1.63994367 |
139 | Upper motor neuron abnormality (HP:0002127) | 1.63810437 |
140 | Diaphragmatic weakness (HP:0009113) | 1.63738649 |
141 | Neuronal loss in central nervous system (HP:0002529) | 1.63641296 |
142 | Hamartoma of the eye (HP:0010568) | 1.63628783 |
143 | Macroorchidism (HP:0000053) | 1.63448094 |
144 | Intestinal polyp (HP:0005266) | 1.63092468 |
145 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.62450261 |
146 | Medulloblastoma (HP:0002885) | 1.61769516 |
147 | Deviation of the hallux (HP:0010051) | 1.61614167 |
148 | Sudden death (HP:0001699) | 1.61450459 |
149 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.61344201 |
150 | Short 1st metacarpal (HP:0010034) | 1.61344201 |
151 | Peripheral hypomyelination (HP:0007182) | 1.61339882 |
152 | Abnormal large intestine physiology (HP:0012700) | 1.61302028 |
153 | Polycythemia (HP:0001901) | 1.61124411 |
154 | Seborrheic dermatitis (HP:0001051) | 1.60943258 |
155 | Colon cancer (HP:0003003) | 1.60817216 |
156 | Short 5th finger (HP:0009237) | 1.59512922 |
157 | Abnormal trabecular bone morphology (HP:0100671) | 1.57870137 |
158 | Bowing of the arm (HP:0006488) | 1.57848267 |
159 | Bowed forearm bones (HP:0003956) | 1.57848267 |
160 | Cafe-au-lait spot (HP:0000957) | 1.57408041 |
161 | High anterior hairline (HP:0009890) | 1.56279815 |
162 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.54713488 |
163 | Flat acetabular roof (HP:0003180) | 1.54493836 |
164 | Spinal rigidity (HP:0003306) | 1.53282340 |
165 | Fatigue (HP:0012378) | 1.53248512 |
166 | Bowel incontinence (HP:0002607) | 1.53180917 |
167 | Premature skin wrinkling (HP:0100678) | 1.52921555 |
168 | Hammertoe (HP:0001765) | 1.52721391 |
169 | Long eyelashes (HP:0000527) | 1.51156230 |
170 | Overlapping toe (HP:0001845) | 1.50664485 |
171 | Thin ribs (HP:0000883) | 1.50295048 |
172 | Distal sensory impairment (HP:0002936) | 1.50262386 |
173 | Glossoptosis (HP:0000162) | 1.49506768 |
174 | Elbow flexion contracture (HP:0002987) | 1.49048299 |
175 | Microretrognathia (HP:0000308) | 1.48431177 |
176 | Self-mutilation (HP:0000742) | 1.48145142 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.48028813 |
2 | SMG1 | 4.15656930 |
3 | MAP3K10 | 3.77615524 |
4 | EEF2K | 3.67330799 |
5 | PKN2 | 3.60830466 |
6 | CDK12 | 3.58211096 |
7 | PRPF4B | 3.11653611 |
8 | ICK | 2.86415200 |
9 | NME2 | 2.79861699 |
10 | IRAK3 | 2.71578084 |
11 | VRK2 | 2.65542227 |
12 | NEK2 | 2.10711480 |
13 | NEK1 | 1.96503680 |
14 | CDC7 | 1.95850462 |
15 | TTN | 1.90063296 |
16 | TAOK2 | 1.87673883 |
17 | ALK | 1.80212145 |
18 | TESK1 | 1.73787620 |
19 | SCYL2 | 1.72102451 |
20 | LATS2 | 1.70485687 |
21 | TYRO3 | 1.63075932 |
22 | PDGFRA | 1.54793566 |
23 | BMX | 1.54767714 |
24 | PTK6 | 1.48024881 |
25 | LATS1 | 1.47868094 |
26 | ERN1 | 1.47152064 |
27 | RIPK1 | 1.46599369 |
28 | ARAF | 1.41546575 |
29 | MTOR | 1.41442342 |
30 | RPS6KB2 | 1.38826106 |
31 | SIK3 | 1.38044582 |
32 | PIM2 | 1.35407771 |
33 | STK10 | 1.35352867 |
34 | CDK4 | 1.31020420 |
35 | PAK4 | 1.28647284 |
36 | BUB1 | 1.26847735 |
37 | SIK1 | 1.25767469 |
38 | LRRK2 | 1.23689551 |
39 | CDK6 | 1.19690447 |
40 | GRK6 | 1.19330608 |
41 | TAOK1 | 1.17746999 |
42 | DDR2 | 1.17644049 |
43 | MAP3K8 | 1.13607326 |
44 | KSR2 | 1.06308107 |
45 | TTK | 1.05491570 |
46 | SRPK1 | 1.04821446 |
47 | PRKD3 | 1.00948424 |
48 | EPHA2 | 0.95286891 |
49 | CDK7 | 0.92143141 |
50 | MAP3K3 | 0.89467141 |
51 | MAP3K9 | 0.87532990 |
52 | DMPK | 0.86538260 |
53 | CDK9 | 0.85705408 |
54 | EIF2AK1 | 0.85193664 |
55 | MAP4K1 | 0.83391794 |
56 | MAP3K11 | 0.82892743 |
57 | WEE1 | 0.82789985 |
58 | CHEK1 | 0.82770737 |
59 | SIK2 | 0.81039855 |
60 | BRAF | 0.80358667 |
61 | IRAK2 | 0.78549844 |
62 | MAP2K2 | 0.76175221 |
63 | CAMK1D | 0.74631970 |
64 | PAK2 | 0.72883757 |
65 | TESK2 | 0.72419939 |
66 | BRSK1 | 0.71891977 |
67 | MAP2K3 | 0.71121624 |
68 | CDK2 | 0.71018303 |
69 | KDR | 0.69461802 |
70 | PAK6 | 0.68897596 |
71 | TBK1 | 0.68325735 |
72 | PIM1 | 0.68325229 |
73 | KSR1 | 0.68141889 |
74 | MAP3K1 | 0.67946435 |
75 | AKT2 | 0.67206750 |
76 | ILK | 0.66444778 |
77 | CDK8 | 0.66301708 |
78 | STK4 | 0.66143923 |
79 | MARK2 | 0.65081764 |
80 | PLK1 | 0.64353448 |
81 | PTK2 | 0.64080558 |
82 | STK3 | 0.63959655 |
83 | PASK | 0.63486033 |
84 | RPS6KA1 | 0.62925004 |
85 | UHMK1 | 0.62505963 |
86 | FGFR1 | 0.62264301 |
87 | EPHB1 | 0.59538240 |
88 | RAF1 | 0.59322480 |
89 | FLT3 | 0.59239025 |
90 | DAPK1 | 0.58996404 |
91 | MAP3K7 | 0.58925525 |
92 | DYRK1B | 0.57898182 |
93 | IRAK4 | 0.57755305 |
94 | MAPK11 | 0.57564500 |
95 | PHKG1 | 0.56629151 |
96 | PHKG2 | 0.56629151 |
97 | RPS6KA4 | 0.55926640 |
98 | CHEK2 | 0.54905449 |
99 | DYRK3 | 0.54581860 |
100 | AURKB | 0.53852923 |
101 | RPS6KA2 | 0.53813583 |
102 | TSSK6 | 0.52241902 |
103 | STK38 | 0.51978110 |
104 | CDC42BPA | 0.51719407 |
105 | CAMK1G | 0.51045362 |
106 | RIPK4 | 0.49217379 |
107 | PDGFRB | 0.49195419 |
108 | MELK | 0.48726282 |
109 | AURKA | 0.48485702 |
110 | CDK11A | 0.48064742 |
111 | MAP3K6 | 0.47841781 |
112 | CSNK1E | 0.47432634 |
113 | LIMK1 | 0.45221248 |
114 | RET | 0.45206314 |
115 | BCKDK | 0.44371766 |
116 | ATR | 0.44328236 |
117 | FGFR4 | 0.44026319 |
118 | PDPK1 | 0.43757461 |
119 | PRKAA1 | 0.43737218 |
120 | PBK | 0.43705291 |
121 | NME1 | 0.42931219 |
122 | GSK3A | 0.42603431 |
123 | CDK15 | 0.42194508 |
124 | NTRK1 | 0.41887594 |
125 | RPS6KL1 | 0.41714329 |
126 | RPS6KC1 | 0.41714329 |
127 | BRD4 | 0.41610936 |
128 | FGFR3 | 0.40400940 |
129 | MET | 0.40296116 |
130 | ATM | 0.39920452 |
131 | MARK3 | 0.39297177 |
132 | PRKD2 | 0.38853025 |
133 | CDK14 | 0.38561507 |
134 | CDK18 | 0.38464099 |
135 | CDK1 | 0.37988672 |
136 | PAK1 | 0.37773648 |
137 | CSNK1D | 0.37688315 |
138 | CSK | 0.36456819 |
139 | HIPK2 | 0.35438656 |
140 | MATK | 0.35300051 |
141 | MAPKAPK2 | 0.34796774 |
142 | TAF1 | 0.34555825 |
143 | RPS6KA6 | 0.33044039 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RNA transport_Homo sapiens_hsa03013 | 2.26077368 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.18092986 |
3 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.09427991 |
4 | mTOR signaling pathway_Homo sapiens_hsa04150 | 2.04686193 |
5 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.00945338 |
6 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.84338200 |
7 | DNA replication_Homo sapiens_hsa03030 | 1.82745067 |
8 | Spliceosome_Homo sapiens_hsa03040 | 1.81509515 |
9 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.78827091 |
10 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.77724328 |
11 | Lysine degradation_Homo sapiens_hsa00310 | 1.72367883 |
12 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.68972724 |
13 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.66842227 |
14 | Cell cycle_Homo sapiens_hsa04110 | 1.65493307 |
15 | Bladder cancer_Homo sapiens_hsa05219 | 1.62647723 |
16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62153679 |
17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.60406799 |
18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.53613228 |
19 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.52954780 |
20 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.51398491 |
21 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.49121016 |
22 | Mismatch repair_Homo sapiens_hsa03430 | 1.45155904 |
23 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.42218783 |
24 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.38884206 |
25 | Other glycan degradation_Homo sapiens_hsa00511 | 1.37486878 |
26 | Endometrial cancer_Homo sapiens_hsa05213 | 1.36489553 |
27 | Base excision repair_Homo sapiens_hsa03410 | 1.35856492 |
28 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.33733597 |
29 | Adherens junction_Homo sapiens_hsa04520 | 1.31752022 |
30 | Colorectal cancer_Homo sapiens_hsa05210 | 1.29973159 |
31 | Prion diseases_Homo sapiens_hsa05020 | 1.28908931 |
32 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.28508621 |
33 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.27987873 |
34 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.27089420 |
35 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.25609016 |
36 | Thyroid cancer_Homo sapiens_hsa05216 | 1.24155442 |
37 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.23758451 |
38 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.23173095 |
39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.22567536 |
40 | Galactose metabolism_Homo sapiens_hsa00052 | 1.22502754 |
41 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.20936916 |
42 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.18844760 |
43 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.17209973 |
44 | Carbon metabolism_Homo sapiens_hsa01200 | 1.15209193 |
45 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.15138732 |
46 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.15015484 |
47 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.14720809 |
48 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.14082314 |
49 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.13209738 |
50 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.12770411 |
51 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.11372111 |
52 | Glioma_Homo sapiens_hsa05214 | 1.09867433 |
53 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.09411540 |
54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.08367880 |
55 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.07983170 |
56 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.06832713 |
57 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05751674 |
58 | Insulin resistance_Homo sapiens_hsa04931 | 1.05263472 |
59 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.04357014 |
60 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.03498331 |
61 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.01573440 |
62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.99564904 |
63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.99133566 |
64 | Sulfur relay system_Homo sapiens_hsa04122 | 0.98947394 |
65 | Shigellosis_Homo sapiens_hsa05131 | 0.98673442 |
66 | Focal adhesion_Homo sapiens_hsa04510 | 0.97922084 |
67 | Ribosome_Homo sapiens_hsa03010 | 0.97672611 |
68 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.96161295 |
69 | Tight junction_Homo sapiens_hsa04530 | 0.96057688 |
70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.93228543 |
71 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.92081788 |
72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.91799044 |
73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.90397070 |
74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.89547866 |
75 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.88987560 |
76 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.86788333 |
77 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.85922208 |
78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.85508642 |
79 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.84609461 |
80 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.82746282 |
81 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.82120641 |
82 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.75578345 |
83 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.74946484 |
84 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.74451130 |
85 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.73340162 |
86 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.73148606 |
87 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.72397106 |
88 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.71681928 |
89 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.71585094 |
90 | Prostate cancer_Homo sapiens_hsa05215 | 0.70248960 |
91 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.68264128 |
92 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.67153954 |
93 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.66987636 |
94 | Pathways in cancer_Homo sapiens_hsa05200 | 0.66424969 |
95 | Hepatitis C_Homo sapiens_hsa05160 | 0.65664411 |
96 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.65111189 |
97 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.64571084 |
98 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.64295931 |
99 | RNA polymerase_Homo sapiens_hsa03020 | 0.64152908 |
100 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.63624280 |
101 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.62456886 |
102 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.61840056 |
103 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.61282925 |
104 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.60055735 |
105 | Influenza A_Homo sapiens_hsa05164 | 0.59366568 |
106 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.58456729 |
107 | Apoptosis_Homo sapiens_hsa04210 | 0.58185998 |
108 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.56103701 |
109 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.55339931 |
110 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.55041854 |
111 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.53686262 |
112 | Hepatitis B_Homo sapiens_hsa05161 | 0.52638244 |
113 | Proteasome_Homo sapiens_hsa03050 | 0.52376979 |
114 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50778861 |
115 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50206310 |
116 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.50143633 |
117 | * Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.49027635 |
118 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.48954212 |
119 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.48787464 |
120 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.48356591 |
121 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48354148 |
122 | Endocytosis_Homo sapiens_hsa04144 | 0.47511570 |
123 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.47179061 |
124 | Amoebiasis_Homo sapiens_hsa05146 | 0.46296211 |
125 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.46115519 |
126 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.46015212 |
127 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.44772614 |
128 | Salmonella infection_Homo sapiens_hsa05132 | 0.43574822 |
129 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43226968 |
130 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.39923925 |
131 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.37954589 |