Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of posttranscriptional gene silencing (GO:0060147) | 5.52613090 |
2 | regulation of gene silencing by miRNA (GO:0060964) | 5.52613090 |
3 | regulation of gene silencing by RNA (GO:0060966) | 5.52613090 |
4 | establishment of integrated proviral latency (GO:0075713) | 5.02054672 |
5 | protein K6-linked ubiquitination (GO:0085020) | 4.99652825 |
6 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.91940150 |
7 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.91940150 |
8 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.91940150 |
9 | formation of translation preinitiation complex (GO:0001731) | 4.90963018 |
10 | regulation of histone H3-K9 methylation (GO:0051570) | 4.72298969 |
11 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.71539608 |
12 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.71539608 |
13 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 4.65573709 |
14 | protein localization to kinetochore (GO:0034501) | 4.62445770 |
15 | DNA replication checkpoint (GO:0000076) | 4.45299741 |
16 | L-serine metabolic process (GO:0006563) | 4.44354874 |
17 | nuclear pore organization (GO:0006999) | 4.43716030 |
18 | histone H4-K12 acetylation (GO:0043983) | 4.30805392 |
19 | single strand break repair (GO:0000012) | 4.30480589 |
20 | DNA replication initiation (GO:0006270) | 4.27541179 |
21 | nuclear pore complex assembly (GO:0051292) | 4.27182701 |
22 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.26617894 |
23 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.26617894 |
24 | mitotic sister chromatid segregation (GO:0000070) | 4.25888741 |
25 | ribosome biogenesis (GO:0042254) | 4.22842061 |
26 | mitotic metaphase plate congression (GO:0007080) | 4.18792796 |
27 | regulation of helicase activity (GO:0051095) | 4.15308754 |
28 | heterochromatin organization (GO:0070828) | 4.05330115 |
29 | regulation of telomere maintenance via telomerase (GO:0032210) | 4.01565666 |
30 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 4.00142457 |
31 | DNA unwinding involved in DNA replication (GO:0006268) | 3.90705155 |
32 | transcription from mitochondrial promoter (GO:0006390) | 3.89970150 |
33 | replication fork processing (GO:0031297) | 3.89786480 |
34 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.88948827 |
35 | chromatin remodeling at centromere (GO:0031055) | 3.87386450 |
36 | determination of adult lifespan (GO:0008340) | 3.87298156 |
37 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 3.84381635 |
38 | regulation of cell fate specification (GO:0042659) | 3.83980518 |
39 | daunorubicin metabolic process (GO:0044597) | 3.81596488 |
40 | polyketide metabolic process (GO:0030638) | 3.81596488 |
41 | doxorubicin metabolic process (GO:0044598) | 3.81596488 |
42 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.81047897 |
43 | mitotic nuclear envelope disassembly (GO:0007077) | 3.77461201 |
44 | lung-associated mesenchyme development (GO:0060484) | 3.72447798 |
45 | establishment of viral latency (GO:0019043) | 3.66675096 |
46 | cullin deneddylation (GO:0010388) | 3.66666920 |
47 | mitochondrial DNA metabolic process (GO:0032042) | 3.65387875 |
48 | DNA strand elongation (GO:0022616) | 3.64761397 |
49 | CENP-A containing nucleosome assembly (GO:0034080) | 3.63225473 |
50 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.62993339 |
51 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.62020098 |
52 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.62020098 |
53 | negative regulation of telomerase activity (GO:0051974) | 3.61624925 |
54 | nucleobase biosynthetic process (GO:0046112) | 3.56877723 |
55 | protein localization to chromosome, centromeric region (GO:0071459) | 3.56369263 |
56 | anterior/posterior axis specification, embryo (GO:0008595) | 3.56025275 |
57 | histone H4-K5 acetylation (GO:0043981) | 3.55894458 |
58 | histone H4-K8 acetylation (GO:0043982) | 3.55894458 |
59 | sister chromatid segregation (GO:0000819) | 3.54290319 |
60 | lysine catabolic process (GO:0006554) | 3.52404110 |
61 | lysine metabolic process (GO:0006553) | 3.52404110 |
62 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.50706937 |
63 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.50566234 |
64 | pore complex assembly (GO:0046931) | 3.50462813 |
65 | membrane disassembly (GO:0030397) | 3.49066976 |
66 | nuclear envelope disassembly (GO:0051081) | 3.49066976 |
67 | regulation of chromatin silencing (GO:0031935) | 3.48622017 |
68 | intestinal epithelial cell development (GO:0060576) | 3.44758246 |
69 | DNA double-strand break processing (GO:0000729) | 3.43593313 |
70 | embryonic process involved in female pregnancy (GO:0060136) | 3.43342068 |
71 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.43271223 |
72 | regulation of SMAD protein import into nucleus (GO:0060390) | 3.43267016 |
73 | purine nucleobase biosynthetic process (GO:0009113) | 3.40706211 |
74 | metaphase plate congression (GO:0051310) | 3.39821287 |
75 | DNA duplex unwinding (GO:0032508) | 3.38955792 |
76 | DNA geometric change (GO:0032392) | 3.37300879 |
77 | histone exchange (GO:0043486) | 3.37060918 |
78 | positive regulation of chromosome segregation (GO:0051984) | 3.36350943 |
79 | regulation of translation in response to stress (GO:0043555) | 3.34681216 |
80 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.34383082 |
81 | establishment of apical/basal cell polarity (GO:0035089) | 3.30676293 |
82 | proline biosynthetic process (GO:0006561) | 3.28118815 |
83 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.27274769 |
84 | DNA replication-independent nucleosome organization (GO:0034724) | 3.27274769 |
85 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 3.26958543 |
86 | rRNA modification (GO:0000154) | 3.25040811 |
87 | regulation of double-strand break repair (GO:2000779) | 3.25008579 |
88 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.24300791 |
89 | negative regulation of sister chromatid segregation (GO:0033046) | 3.24300791 |
90 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.24300791 |
91 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.24300791 |
92 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.24300791 |
93 | IMP metabolic process (GO:0046040) | 3.23971990 |
94 | protein deneddylation (GO:0000338) | 3.22682412 |
95 | regulation of cell fate commitment (GO:0010453) | 3.22174783 |
96 | somite rostral/caudal axis specification (GO:0032525) | 3.21705625 |
97 | mitotic chromosome condensation (GO:0007076) | 3.20907472 |
98 | pre-miRNA processing (GO:0031054) | 3.19720536 |
99 | trophectodermal cell differentiation (GO:0001829) | 3.19423271 |
100 | IMP biosynthetic process (GO:0006188) | 3.18774444 |
101 | chromatin assembly (GO:0031497) | 3.18520382 |
102 | ribosome assembly (GO:0042255) | 3.16009849 |
103 | DNA damage response, detection of DNA damage (GO:0042769) | 3.11909261 |
104 | paraxial mesoderm development (GO:0048339) | 3.10562144 |
105 | negative regulation of gene silencing (GO:0060969) | 3.09415139 |
106 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.09009185 |
107 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.05292488 |
108 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.04147938 |
109 | non-recombinational repair (GO:0000726) | 3.04147938 |
110 | ncRNA catabolic process (GO:0034661) | 3.04108143 |
111 | negative regulation of androgen receptor signaling pathway (GO:0060766) | 3.02102726 |
112 | regulation of gene silencing (GO:0060968) | 3.00931182 |
113 | pseudouridine synthesis (GO:0001522) | 3.00663511 |
114 | regulation of translational fidelity (GO:0006450) | 2.99841673 |
115 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.98226578 |
116 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.98226578 |
117 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.98226578 |
118 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.96395397 |
119 | mitotic spindle checkpoint (GO:0071174) | 2.95734247 |
120 | nodal signaling pathway (GO:0038092) | 2.94875179 |
121 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.93856343 |
122 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.93223556 |
123 | ATP-dependent chromatin remodeling (GO:0043044) | 2.92321462 |
124 | negative regulation of chromosome segregation (GO:0051985) | 2.92049932 |
125 | telomere maintenance via recombination (GO:0000722) | 2.91550161 |
126 | telomere maintenance via telomerase (GO:0007004) | 2.91243342 |
127 | female gonad development (GO:0008585) | 2.91228603 |
128 | spindle checkpoint (GO:0031577) | 2.91142954 |
129 | mitotic sister chromatid cohesion (GO:0007064) | 2.88050445 |
130 | mitotic recombination (GO:0006312) | 2.87233516 |
131 | cellular protein complex localization (GO:0034629) | 2.86652248 |
132 | rRNA processing (GO:0006364) | 2.86420191 |
133 | regulation of chromosome segregation (GO:0051983) | 2.86362950 |
134 | rRNA transcription (GO:0009303) | 2.85232413 |
135 | maturation of SSU-rRNA (GO:0030490) | 2.85151565 |
136 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.85081199 |
137 | maintenance of protein location in nucleus (GO:0051457) | 2.84901788 |
138 | establishment of chromosome localization (GO:0051303) | 2.84708295 |
139 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 2.84036206 |
140 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 2.84036206 |
141 | negative regulation of histone methylation (GO:0031061) | 2.83636634 |
142 | protein complex localization (GO:0031503) | 2.83380846 |
143 | telomere maintenance via telomere lengthening (GO:0010833) | 2.83091885 |
144 | mitochondrial RNA metabolic process (GO:0000959) | 2.83081946 |
145 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.82885773 |
146 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.82885773 |
147 | regulation of sister chromatid segregation (GO:0033045) | 2.82885773 |
148 | serine family amino acid biosynthetic process (GO:0009070) | 2.82838692 |
149 | DNA demethylation (GO:0080111) | 2.82718391 |
150 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.82712160 |
151 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.82712160 |
152 | meiotic chromosome segregation (GO:0045132) | 2.81564591 |
153 | kinetochore assembly (GO:0051382) | 2.81181437 |
154 | mitotic spindle assembly checkpoint (GO:0007094) | 2.76150209 |
155 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.74985778 |
156 | regulation of timing of cell differentiation (GO:0048505) | 2.74572004 |
157 | negative regulation of mRNA processing (GO:0050686) | 2.73762918 |
158 | regulation of development, heterochronic (GO:0040034) | 2.73547094 |
159 | notochord development (GO:0030903) | 2.71149740 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.02281593 |
2 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 4.41356516 |
3 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 4.41356516 |
4 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 4.41356516 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.61781617 |
6 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 3.42108469 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.14487922 |
8 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 3.03290997 |
9 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 2.99742061 |
10 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.99304342 |
11 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.91563187 |
12 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.84919292 |
13 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 2.56279573 |
14 | * POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.53097179 |
15 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 2.51360633 |
16 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.49403841 |
17 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 2.47838112 |
18 | * SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.45863954 |
19 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.40899739 |
20 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 2.39391626 |
21 | * TCF3_18692474_ChIP-Seq_MESCs_Mouse | 2.35937241 |
22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.33201400 |
23 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 2.32060330 |
24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.29286877 |
25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.24482912 |
26 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.23704879 |
27 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.15051935 |
28 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 2.06069182 |
29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.03736716 |
30 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.02392960 |
31 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.99698945 |
32 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.99653780 |
33 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.95175425 |
34 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.95104010 |
35 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.93561620 |
36 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.89125451 |
37 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.84950460 |
38 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.83050242 |
39 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.82717141 |
40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81861553 |
41 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.81115518 |
42 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.79991720 |
43 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.79455614 |
44 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.78142982 |
45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.76203927 |
46 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.76111151 |
47 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.75789054 |
48 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.74904853 |
49 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.73891245 |
50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.72765710 |
51 | * NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.71713848 |
52 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.70352299 |
53 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.68417603 |
54 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.67945420 |
55 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.63698670 |
56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.62210813 |
57 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.61515265 |
58 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.61198150 |
59 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.60473136 |
60 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.57421802 |
61 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.55829970 |
62 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.55488284 |
63 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.52919142 |
64 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.49294006 |
65 | * NANOG_18692474_ChIP-Seq_MESCs_Mouse | 1.48268293 |
66 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.47674844 |
67 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.47214310 |
68 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.47053151 |
69 | EWS_26573619_Chip-Seq_HEK293_Human | 1.46248977 |
70 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.46162207 |
71 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.43868573 |
72 | * POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 1.42362729 |
73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.40900154 |
74 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.37147573 |
75 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.36748353 |
76 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.36565713 |
77 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.36067480 |
78 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.33742226 |
79 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.32408643 |
80 | VDR_22108803_ChIP-Seq_LS180_Human | 1.31128297 |
81 | * FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.30068970 |
82 | * TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 1.29884273 |
83 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.28217818 |
84 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.27181078 |
85 | FUS_26573619_Chip-Seq_HEK293_Human | 1.26830284 |
86 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.26636233 |
87 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.26164863 |
88 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25045413 |
89 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.22221577 |
90 | MYC_22102868_ChIP-Seq_BL_Human | 1.20758585 |
91 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.19322668 |
92 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17825624 |
93 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.17633316 |
94 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 1.17505782 |
95 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.13664417 |
96 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.12945762 |
97 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.12745978 |
98 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.12212474 |
99 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.11866492 |
100 | KAP1_27257070_Chip-Seq_ESCs_Mouse | 1.11306305 |
101 | * PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 1.09800904 |
102 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.08289685 |
103 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07509413 |
104 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.07509413 |
105 | * TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.07458953 |
106 | * TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.06500889 |
107 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.06150199 |
108 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.03078547 |
109 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.02928295 |
110 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.02718687 |
111 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.02664469 |
112 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.00608251 |
113 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.00250881 |
114 | * POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.98769839 |
115 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98294465 |
116 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98081069 |
117 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92396870 |
118 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92263878 |
119 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.92150159 |
120 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.91852600 |
121 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.91704557 |
122 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.90612742 |
123 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.89929694 |
124 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.87803981 |
125 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.86051012 |
126 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.83142156 |
127 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.80063470 |
128 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.79210003 |
129 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.78311512 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.14150929 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.20957662 |
3 | MP0010094_abnormal_chromosome_stability | 3.63329711 |
4 | MP0003111_abnormal_nucleus_morphology | 3.57420250 |
5 | MP0003693_abnormal_embryo_hatching | 3.41176807 |
6 | MP0003806_abnormal_nucleotide_metabolis | 3.19071161 |
7 | MP0008058_abnormal_DNA_repair | 3.13946289 |
8 | MP0004133_heterotaxia | 3.09106053 |
9 | MP0003077_abnormal_cell_cycle | 3.04981001 |
10 | MP0002653_abnormal_ependyma_morphology | 3.04024752 |
11 | MP0003890_abnormal_embryonic-extraembry | 2.93472264 |
12 | MP0003283_abnormal_digestive_organ | 2.83430200 |
13 | MP0009672_abnormal_birth_weight | 2.70678694 |
14 | MP0010352_gastrointestinal_tract_polyps | 2.61775716 |
15 | MP0002277_abnormal_respiratory_mucosa | 2.40006234 |
16 | MP0006292_abnormal_olfactory_placode | 2.31063289 |
17 | MP0000350_abnormal_cell_proliferation | 2.15495799 |
18 | MP0003123_paternal_imprinting | 2.15186486 |
19 | MP0005380_embryogenesis_phenotype | 2.13745525 |
20 | MP0001672_abnormal_embryogenesis/_devel | 2.13745525 |
21 | MP0001730_embryonic_growth_arrest | 2.13140994 |
22 | MP0004264_abnormal_extraembryonic_tissu | 2.05818727 |
23 | MP0008932_abnormal_embryonic_tissue | 2.04914194 |
24 | MP0003787_abnormal_imprinting | 1.97533757 |
25 | MP0002084_abnormal_developmental_patter | 1.92383257 |
26 | MP0002085_abnormal_embryonic_tissue | 1.87932797 |
27 | MP0003136_yellow_coat_color | 1.83672185 |
28 | MP0003984_embryonic_growth_retardation | 1.83669826 |
29 | MP0003119_abnormal_digestive_system | 1.82957760 |
30 | MP0002086_abnormal_extraembryonic_tissu | 1.82681148 |
31 | MP0002088_abnormal_embryonic_growth/wei | 1.80827278 |
32 | MP0001293_anophthalmia | 1.78979340 |
33 | MP0003786_premature_aging | 1.76779963 |
34 | MP0001697_abnormal_embryo_size | 1.76684445 |
35 | MP0010030_abnormal_orbit_morphology | 1.72290763 |
36 | MP0008007_abnormal_cellular_replicative | 1.71592524 |
37 | MP0004197_abnormal_fetal_growth/weight/ | 1.62031972 |
38 | MP0003718_maternal_effect | 1.57169568 |
39 | MP0001188_hyperpigmentation | 1.55853991 |
40 | MP0005266_abnormal_metabolism | 1.49379768 |
41 | MP0002697_abnormal_eye_size | 1.47745686 |
42 | MP0002080_prenatal_lethality | 1.42548453 |
43 | MP0001299_abnormal_eye_distance/ | 1.42135379 |
44 | MP0001849_ear_inflammation | 1.39056830 |
45 | MP0000537_abnormal_urethra_morphology | 1.38941061 |
46 | MP0003705_abnormal_hypodermis_morpholog | 1.36990590 |
47 | MP0003941_abnormal_skin_development | 1.34856377 |
48 | MP0010307_abnormal_tumor_latency | 1.34294078 |
49 | MP0005075_abnormal_melanosome_morpholog | 1.32159610 |
50 | MP0002938_white_spotting | 1.29479126 |
51 | MP0010234_abnormal_vibrissa_follicle | 1.29186006 |
52 | MP0002751_abnormal_autonomic_nervous | 1.27589920 |
53 | MP0008877_abnormal_DNA_methylation | 1.25487372 |
54 | MP0000049_abnormal_middle_ear | 1.23858880 |
55 | MP0003121_genomic_imprinting | 1.22341621 |
56 | MP0005076_abnormal_cell_differentiation | 1.20349128 |
57 | MP0000490_abnormal_crypts_of | 1.18400213 |
58 | MP0008789_abnormal_olfactory_epithelium | 1.16824711 |
59 | MP0001145_abnormal_male_reproductive | 1.15265932 |
60 | MP0000566_synostosis | 1.15038715 |
61 | MP0009278_abnormal_bone_marrow | 1.14965533 |
62 | MP0002736_abnormal_nociception_after | 1.14672126 |
63 | MP0005377_hearing/vestibular/ear_phenot | 1.13356697 |
64 | MP0003878_abnormal_ear_physiology | 1.13356697 |
65 | MP0003567_abnormal_fetal_cardiomyocyte | 1.10098575 |
66 | MP0002254_reproductive_system_inflammat | 1.09663381 |
67 | MP0000313_abnormal_cell_death | 1.09222273 |
68 | MP0003646_muscle_fatigue | 1.08938459 |
69 | MP0002233_abnormal_nose_morphology | 1.08759287 |
70 | MP0002210_abnormal_sex_determination | 1.07593398 |
71 | MP0001485_abnormal_pinna_reflex | 1.07009804 |
72 | MP0000428_abnormal_craniofacial_morphol | 1.05747220 |
73 | MP0002163_abnormal_gland_morphology | 1.03194008 |
74 | MP0000579_abnormal_nail_morphology | 1.02698211 |
75 | MP0003122_maternal_imprinting | 1.00488231 |
76 | MP0006072_abnormal_retinal_apoptosis | 0.96675009 |
77 | MP0006035_abnormal_mitochondrial_morpho | 0.96142975 |
78 | MP0002019_abnormal_tumor_incidence | 0.95487467 |
79 | MP0002092_abnormal_eye_morphology | 0.95345784 |
80 | MP0009697_abnormal_copulation | 0.93931179 |
81 | MP0001984_abnormal_olfaction | 0.93129983 |
82 | MP0002332_abnormal_exercise_endurance | 0.93119886 |
83 | MP0003755_abnormal_palate_morphology | 0.92516949 |
84 | MP0002111_abnormal_tail_morphology | 0.90580369 |
85 | MP0002090_abnormal_vision | 0.90305720 |
86 | MP0009703_decreased_birth_body | 0.89932245 |
87 | MP0005367_renal/urinary_system_phenotyp | 0.89648645 |
88 | MP0000516_abnormal_urinary_system | 0.89648645 |
89 | MP0003315_abnormal_perineum_morphology | 0.89437242 |
90 | MP0001529_abnormal_vocalization | 0.88993382 |
91 | MP0005395_other_phenotype | 0.87271642 |
92 | MP0002796_impaired_skin_barrier | 0.87171332 |
93 | MP0000631_abnormal_neuroendocrine_gland | 0.87074325 |
94 | MP0002102_abnormal_ear_morphology | 0.86236047 |
95 | MP0000371_diluted_coat_color | 0.86178657 |
96 | MP0004142_abnormal_muscle_tone | 0.85504042 |
97 | MP0000432_abnormal_head_morphology | 0.84971119 |
98 | MP0000647_abnormal_sebaceous_gland | 0.83643012 |
99 | MP0002249_abnormal_larynx_morphology | 0.83003820 |
100 | MP0002269_muscular_atrophy | 0.82616930 |
101 | MP0003566_abnormal_cell_adhesion | 0.80757431 |
102 | MP0000653_abnormal_sex_gland | 0.80171486 |
103 | MP0003935_abnormal_craniofacial_develop | 0.79566221 |
104 | MP0001286_abnormal_eye_development | 0.79419449 |
105 | MP0003936_abnormal_reproductive_system | 0.79368611 |
106 | MP0000678_abnormal_parathyroid_gland | 0.79130810 |
107 | * MP0001929_abnormal_gametogenesis | 0.78941014 |
108 | MP0003172_abnormal_lysosome_physiology | 0.77951007 |
109 | MP0002127_abnormal_cardiovascular_syste | 0.77656860 |
110 | MP0008770_decreased_survivor_rate | 0.77060130 |
111 | MP0005501_abnormal_skin_physiology | 0.74845150 |
112 | MP0003453_abnormal_keratinocyte_physiol | 0.74735183 |
113 | MP0001177_atelectasis | 0.73956547 |
114 | MP0004233_abnormal_muscle_weight | 0.73282159 |
115 | MP0005023_abnormal_wound_healing | 0.73074004 |
116 | MP0000762_abnormal_tongue_morphology | 0.72072187 |
117 | MP0005394_taste/olfaction_phenotype | 0.71838012 |
118 | MP0005499_abnormal_olfactory_system | 0.71838012 |
119 | MP0000358_abnormal_cell_content/ | 0.71581999 |
120 | MP0003861_abnormal_nervous_system | 0.70066508 |
121 | MP0003186_abnormal_redox_activity | 0.68321598 |
122 | MP0005397_hematopoietic_system_phenotyp | 0.68257016 |
123 | MP0001545_abnormal_hematopoietic_system | 0.68257016 |
124 | MP0005379_endocrine/exocrine_gland_phen | 0.67597979 |
125 | MP0005384_cellular_phenotype | 0.67278542 |
126 | MP0004185_abnormal_adipocyte_glucose | 0.66987990 |
127 | MP0002114_abnormal_axial_skeleton | 0.66514116 |
128 | MP0003937_abnormal_limbs/digits/tail_de | 0.65814101 |
129 | MP0002075_abnormal_coat/hair_pigmentati | 0.65796604 |
130 | MP0003938_abnormal_ear_development | 0.64790895 |
131 | MP0005621_abnormal_cell_physiology | 0.64348866 |
132 | MP0006276_abnormal_autonomic_nervous | 0.62312203 |
133 | MP0002081_perinatal_lethality | 0.60710764 |
134 | MP0004270_analgesia | 0.60456908 |
135 | MP0001346_abnormal_lacrimal_gland | 0.60400883 |
136 | MP0003137_abnormal_impulse_conducting | 0.58807600 |
137 | * MP0003698_abnormal_male_reproductive | 0.58415838 |
138 | MP0004147_increased_porphyrin_level | 0.58059594 |
139 | MP0003195_calcinosis | 0.56743761 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 5.61987697 |
2 | Rib fusion (HP:0000902) | 4.32983952 |
3 | Abnormality of the labia minora (HP:0012880) | 4.25289591 |
4 | Abnormality of the astrocytes (HP:0100707) | 4.14050553 |
5 | Astrocytoma (HP:0009592) | 4.14050553 |
6 | Breast hypoplasia (HP:0003187) | 3.91438782 |
7 | Rectovaginal fistula (HP:0000143) | 3.91185319 |
8 | Rectal fistula (HP:0100590) | 3.91185319 |
9 | Septo-optic dysplasia (HP:0100842) | 3.89146206 |
10 | Hypochromic microcytic anemia (HP:0004840) | 3.82497906 |
11 | Aplasia/hypoplasia of the humerus (HP:0006507) | 3.81470237 |
12 | Absent radius (HP:0003974) | 3.72147275 |
13 | Short humerus (HP:0005792) | 3.64093583 |
14 | Birth length less than 3rd percentile (HP:0003561) | 3.59427371 |
15 | Rhabdomyosarcoma (HP:0002859) | 3.58685506 |
16 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.50794171 |
17 | Aplasia involving forearm bones (HP:0009822) | 3.48860055 |
18 | Absent forearm bone (HP:0003953) | 3.48860055 |
19 | Multiple enchondromatosis (HP:0005701) | 3.46848912 |
20 | Intestinal fistula (HP:0100819) | 3.38141294 |
21 | Supernumerary spleens (HP:0009799) | 3.37909151 |
22 | Neoplasm of the oral cavity (HP:0100649) | 3.37110475 |
23 | Glioma (HP:0009733) | 3.35734090 |
24 | Vaginal fistula (HP:0004320) | 3.34027969 |
25 | Chromsome breakage (HP:0040012) | 3.29640571 |
26 | Neoplasm of striated muscle (HP:0009728) | 3.28536984 |
27 | Medulloblastoma (HP:0002885) | 3.24842506 |
28 | Chronic bronchitis (HP:0004469) | 3.19355779 |
29 | Spastic diplegia (HP:0001264) | 3.18836039 |
30 | Impulsivity (HP:0100710) | 3.09839204 |
31 | Abnormality of the salivary glands (HP:0010286) | 3.09238775 |
32 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.09015608 |
33 | Patellar aplasia (HP:0006443) | 3.01267581 |
34 | Selective tooth agenesis (HP:0001592) | 2.99525053 |
35 | Shawl scrotum (HP:0000049) | 2.99295695 |
36 | Bilateral microphthalmos (HP:0007633) | 2.90702541 |
37 | Abnormality of the lower motor neuron (HP:0002366) | 2.88264975 |
38 | Carpal bone hypoplasia (HP:0001498) | 2.86667482 |
39 | Premature ovarian failure (HP:0008209) | 2.84279990 |
40 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.81253467 |
41 | Choanal stenosis (HP:0000452) | 2.81123380 |
42 | Abnormality of the ileum (HP:0001549) | 2.78551879 |
43 | Hyperglycinemia (HP:0002154) | 2.77982822 |
44 | Tongue fasciculations (HP:0001308) | 2.75998685 |
45 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.74330143 |
46 | Neoplasm of the adrenal cortex (HP:0100641) | 2.70934338 |
47 | Malnutrition (HP:0004395) | 2.70348291 |
48 | Agnosia (HP:0010524) | 2.63340010 |
49 | Stenosis of the external auditory canal (HP:0000402) | 2.63239614 |
50 | Meckel diverticulum (HP:0002245) | 2.62537940 |
51 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.58645841 |
52 | Cerebral hypomyelination (HP:0006808) | 2.57375908 |
53 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.56704083 |
54 | Abnormality of the septum pellucidum (HP:0007375) | 2.54900175 |
55 | Absent thumb (HP:0009777) | 2.52562752 |
56 | Abnormality of glycine metabolism (HP:0010895) | 2.51968848 |
57 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.51968848 |
58 | Fused cervical vertebrae (HP:0002949) | 2.51559488 |
59 | Muscle fibrillation (HP:0010546) | 2.50891354 |
60 | Abnormal lung lobation (HP:0002101) | 2.50588472 |
61 | Absent septum pellucidum (HP:0001331) | 2.50072165 |
62 | Trismus (HP:0000211) | 2.49438718 |
63 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.48027172 |
64 | Facial hemangioma (HP:0000329) | 2.46751446 |
65 | Abnormality of abdominal situs (HP:0011620) | 2.43411177 |
66 | Abdominal situs inversus (HP:0003363) | 2.43411177 |
67 | Maternal diabetes (HP:0009800) | 2.38571596 |
68 | Homocystinuria (HP:0002156) | 2.38472069 |
69 | Abnormality of homocysteine metabolism (HP:0010919) | 2.38472069 |
70 | Short hallux (HP:0010109) | 2.38156798 |
71 | Ectopic kidney (HP:0000086) | 2.31691444 |
72 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.31333522 |
73 | Hypoglycemic seizures (HP:0002173) | 2.31150689 |
74 | Aqueductal stenosis (HP:0002410) | 2.29977021 |
75 | Adenoma sebaceum (HP:0009720) | 2.29914255 |
76 | Angiofibromas (HP:0010615) | 2.29914255 |
77 | Colon cancer (HP:0003003) | 2.26808830 |
78 | Optic nerve hypoplasia (HP:0000609) | 2.25474904 |
79 | Embryonal renal neoplasm (HP:0011794) | 2.25230879 |
80 | Protruding tongue (HP:0010808) | 2.24933934 |
81 | Pendular nystagmus (HP:0012043) | 2.24161138 |
82 | Abnormality of the preputium (HP:0100587) | 2.22371129 |
83 | Missing ribs (HP:0000921) | 2.22109045 |
84 | Spinal muscular atrophy (HP:0007269) | 2.22050557 |
85 | Concave nail (HP:0001598) | 2.20255174 |
86 | Degeneration of anterior horn cells (HP:0002398) | 2.19515999 |
87 | Abnormality of the anterior horn cell (HP:0006802) | 2.19515999 |
88 | Abnormality of serum amino acid levels (HP:0003112) | 2.18440808 |
89 | Cortical dysplasia (HP:0002539) | 2.15989712 |
90 | Basal cell carcinoma (HP:0002671) | 2.15959140 |
91 | Abnormal sex determination (HP:0012244) | 2.14732552 |
92 | Sex reversal (HP:0012245) | 2.14732552 |
93 | Abnormal number of incisors (HP:0011064) | 2.13050294 |
94 | Vertebral fusion (HP:0002948) | 2.12142114 |
95 | Abnormality of chromosome stability (HP:0003220) | 2.11593245 |
96 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.10116076 |
97 | Vertebral clefting (HP:0008428) | 2.07185305 |
98 | Facial cleft (HP:0002006) | 2.04870217 |
99 | Delayed puberty (HP:0000823) | 2.02954814 |
100 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.02591460 |
101 | Duodenal stenosis (HP:0100867) | 1.99469785 |
102 | Small intestinal stenosis (HP:0012848) | 1.99469785 |
103 | Esophageal atresia (HP:0002032) | 1.98218821 |
104 | Hypoplastic female external genitalia (HP:0012815) | 1.97928631 |
105 | Rough bone trabeculation (HP:0100670) | 1.96707212 |
106 | Preaxial foot polydactyly (HP:0001841) | 1.96287803 |
107 | Embryonal neoplasm (HP:0002898) | 1.95872262 |
108 | Triphalangeal thumb (HP:0001199) | 1.94944753 |
109 | Cellular immunodeficiency (HP:0005374) | 1.93936442 |
110 | Hyperglycinuria (HP:0003108) | 1.93370130 |
111 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.91421684 |
112 | Hemivertebrae (HP:0002937) | 1.90893278 |
113 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.89216711 |
114 | Hepatoblastoma (HP:0002884) | 1.88907102 |
115 | Tracheoesophageal fistula (HP:0002575) | 1.87328910 |
116 | Metaphyseal cupping (HP:0003021) | 1.87228687 |
117 | Bifid tongue (HP:0010297) | 1.84997097 |
118 | Testicular atrophy (HP:0000029) | 1.84458682 |
119 | Oral leukoplakia (HP:0002745) | 1.83674407 |
120 | Atresia of the external auditory canal (HP:0000413) | 1.83572036 |
121 | Myelodysplasia (HP:0002863) | 1.83497410 |
122 | Volvulus (HP:0002580) | 1.83221358 |
123 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.82715021 |
124 | Hypoplasia of the pons (HP:0012110) | 1.82630330 |
125 | Abnormality of the clitoris (HP:0000056) | 1.81683773 |
126 | Labial hypoplasia (HP:0000066) | 1.81345432 |
127 | Intestinal atresia (HP:0011100) | 1.80634384 |
128 | Dandy-Walker malformation (HP:0001305) | 1.80451291 |
129 | Broad thumb (HP:0011304) | 1.80009220 |
130 | Abnormality of the duodenum (HP:0002246) | 1.79984226 |
131 | Breast aplasia (HP:0100783) | 1.79560150 |
132 | Orthostatic hypotension (HP:0001278) | 1.79387807 |
133 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.78181455 |
134 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.78120044 |
135 | Gastrointestinal atresia (HP:0002589) | 1.77742282 |
136 | Absent eyebrow (HP:0002223) | 1.77644739 |
137 | Horseshoe kidney (HP:0000085) | 1.77392663 |
138 | Neoplasm of the colon (HP:0100273) | 1.77099865 |
139 | Biliary tract neoplasm (HP:0100574) | 1.76287108 |
140 | Supernumerary ribs (HP:0005815) | 1.76190497 |
141 | Cafe-au-lait spot (HP:0000957) | 1.75809395 |
142 | Sloping forehead (HP:0000340) | 1.75080644 |
143 | Hypoplasia of the radius (HP:0002984) | 1.74723474 |
144 | Secondary amenorrhea (HP:0000869) | 1.74669978 |
145 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.74173043 |
146 | Gastrointestinal carcinoma (HP:0002672) | 1.74173043 |
147 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.74147976 |
148 | Vertebral hypoplasia (HP:0008417) | 1.74147976 |
149 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.72545245 |
150 | Progressive inability to walk (HP:0002505) | 1.71421505 |
151 | Neoplasm of the adrenal gland (HP:0100631) | 1.71068965 |
152 | Abnormal hair whorl (HP:0010721) | 1.69689932 |
153 | Clitoromegaly (HP:0000057) | 1.68731463 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 5.40481767 |
2 | WEE1 | 3.75968986 |
3 | AKT3 | 3.41422793 |
4 | TTK | 3.10066468 |
5 | BUB1 | 3.06236076 |
6 | VRK2 | 2.99740348 |
7 | EPHA2 | 2.96458923 |
8 | ZAK | 2.90861974 |
9 | TAF1 | 2.73970137 |
10 | CDC7 | 2.61712944 |
11 | TNIK | 2.53459876 |
12 | NEK1 | 2.48587937 |
13 | CDK7 | 2.43696080 |
14 | PBK | 2.27866603 |
15 | PLK1 | 2.27120213 |
16 | ICK | 2.09119975 |
17 | NUAK1 | 2.02179961 |
18 | WNK3 | 2.01924987 |
19 | TYRO3 | 1.98118456 |
20 | NEK2 | 1.96123134 |
21 | CHEK2 | 1.85559154 |
22 | PLK4 | 1.79549313 |
23 | MATK | 1.79308639 |
24 | CDK19 | 1.75356038 |
25 | DDR2 | 1.74050132 |
26 | GRK5 | 1.68294405 |
27 | FGFR2 | 1.65483698 |
28 | RPS6KB2 | 1.65415849 |
29 | BRSK2 | 1.53457339 |
30 | LATS2 | 1.51095270 |
31 | SMG1 | 1.45552394 |
32 | MAP3K10 | 1.43640915 |
33 | SRPK1 | 1.33134413 |
34 | TSSK6 | 1.30648245 |
35 | TRIM28 | 1.29871305 |
36 | AURKA | 1.29057816 |
37 | CHEK1 | 1.27445616 |
38 | LATS1 | 1.27072552 |
39 | ATR | 1.26848887 |
40 | STK3 | 1.20880741 |
41 | MAP3K6 | 1.20844259 |
42 | PIM2 | 1.20540111 |
43 | ACVR1B | 1.20082495 |
44 | NME1 | 1.16074405 |
45 | ALK | 1.14515975 |
46 | AURKB | 1.14449241 |
47 | STK10 | 1.13729584 |
48 | GRK6 | 1.13696907 |
49 | CDK4 | 1.11903942 |
50 | TESK2 | 1.10882919 |
51 | DYRK3 | 1.10322177 |
52 | FRK | 1.09460534 |
53 | FGFR1 | 1.09345478 |
54 | PAK4 | 1.08436042 |
55 | NLK | 1.08258384 |
56 | PRKCI | 1.06721265 |
57 | PDK4 | 1.04609484 |
58 | PDK3 | 1.04609484 |
59 | ABL2 | 1.04014645 |
60 | PDK2 | 1.03914469 |
61 | CASK | 1.03572723 |
62 | CDK2 | 1.02453296 |
63 | CSNK1G1 | 1.02410006 |
64 | PIM1 | 1.02055691 |
65 | EIF2AK1 | 1.02011269 |
66 | PINK1 | 1.01979672 |
67 | BRD4 | 1.00326904 |
68 | PLK3 | 1.00142329 |
69 | OXSR1 | 0.99786209 |
70 | BMPR1B | 0.99609988 |
71 | ATM | 0.98879922 |
72 | BCKDK | 0.95798350 |
73 | DAPK1 | 0.95144860 |
74 | CDK6 | 0.93354482 |
75 | TIE1 | 0.89169127 |
76 | PNCK | 0.88312781 |
77 | MTOR | 0.86128859 |
78 | CAMK1D | 0.85917546 |
79 | ARAF | 0.83796145 |
80 | STK38L | 0.83113594 |
81 | CAMK1G | 0.82342976 |
82 | DYRK2 | 0.82146730 |
83 | INSRR | 0.80113041 |
84 | LMTK2 | 0.78547868 |
85 | STK24 | 0.77849848 |
86 | BRAF | 0.77343117 |
87 | CSNK1E | 0.77076630 |
88 | MAPKAPK3 | 0.75767882 |
89 | MAP3K8 | 0.74741893 |
90 | BRSK1 | 0.73699317 |
91 | CSNK1G2 | 0.72733100 |
92 | MAP3K11 | 0.72466226 |
93 | YES1 | 0.72438824 |
94 | BMX | 0.72396731 |
95 | ERBB4 | 0.71693938 |
96 | AKT2 | 0.70443764 |
97 | CSK | 0.69567114 |
98 | MAP3K4 | 0.69412378 |
99 | PASK | 0.68329486 |
100 | CSNK2A2 | 0.66974823 |
101 | MAPK15 | 0.65671494 |
102 | CDK1 | 0.64882294 |
103 | EIF2AK3 | 0.61929639 |
104 | MAP4K2 | 0.61832938 |
105 | PLK2 | 0.61761080 |
106 | PRKDC | 0.61653629 |
107 | BCR | 0.60118962 |
108 | PAK1 | 0.60113811 |
109 | MKNK2 | 0.59433300 |
110 | EEF2K | 0.59258400 |
111 | TLK1 | 0.59104537 |
112 | FGR | 0.58566093 |
113 | EIF2AK2 | 0.57911242 |
114 | CSNK1G3 | 0.57876366 |
115 | CSNK2A1 | 0.57642816 |
116 | MAPK7 | 0.57126039 |
117 | ERN1 | 0.56301236 |
118 | PRKG2 | 0.56214059 |
119 | DYRK1A | 0.54402181 |
120 | MELK | 0.54173574 |
121 | STK16 | 0.53928340 |
122 | KDR | 0.51032165 |
123 | NME2 | 0.49817705 |
124 | STK4 | 0.49293952 |
125 | GRK1 | 0.48298503 |
126 | PTK2 | 0.48106112 |
127 | MAP3K9 | 0.46700535 |
128 | EGFR | 0.46212819 |
129 | FLT3 | 0.46002276 |
130 | CDK3 | 0.45205229 |
131 | STK38 | 0.45174910 |
132 | CSNK1D | 0.43942000 |
133 | MET | 0.43612924 |
134 | MAPK10 | 0.42566970 |
135 | CSNK1A1L | 0.41460795 |
136 | MAPK14 | 0.41073385 |
137 | VRK1 | 0.39807386 |
138 | TAOK2 | 0.39511195 |
139 | CSNK1A1 | 0.39029385 |
140 | CSF1R | 0.38891472 |
141 | GSK3A | 0.38637930 |
142 | MKNK1 | 0.38389900 |
143 | UHMK1 | 0.37858670 |
144 | GSK3B | 0.36792979 |
145 | PRKCG | 0.36386837 |
146 | TEC | 0.36048186 |
147 | PRKCE | 0.35841344 |
148 | DYRK1B | 0.35793549 |
149 | MST4 | 0.35496223 |
150 | TGFBR1 | 0.35357654 |
151 | PDGFRA | 0.35062829 |
152 | RPS6KA4 | 0.28613816 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Mismatch repair_Homo sapiens_hsa03430 | 4.82313723 |
2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.65449631 |
3 | DNA replication_Homo sapiens_hsa03030 | 4.42249649 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.56887154 |
5 | Base excision repair_Homo sapiens_hsa03410 | 3.01282916 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 2.87171280 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.86617315 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.69184637 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.62992257 |
10 | Cell cycle_Homo sapiens_hsa04110 | 2.47980493 |
11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.42762978 |
12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.41468331 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.35860180 |
14 | Ribosome_Homo sapiens_hsa03010 | 2.33618820 |
15 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.22311848 |
16 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.03622225 |
17 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.93786771 |
18 | Proteasome_Homo sapiens_hsa03050 | 1.84642105 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.76022005 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.73703250 |
21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.72676886 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.69839182 |
23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.60850626 |
24 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.51045302 |
25 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.44348263 |
26 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.42854475 |
27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.40677669 |
28 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.39258092 |
29 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.25306348 |
30 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.22475765 |
31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.21424331 |
32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.20979665 |
33 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.15964949 |
34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.08234881 |
35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.08175997 |
36 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.08167448 |
37 | Protein export_Homo sapiens_hsa03060 | 1.06617956 |
38 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.05237119 |
39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.04093287 |
40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.02846732 |
41 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.99387099 |
42 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.98986548 |
43 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.93047331 |
44 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.92938149 |
45 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.92416030 |
46 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.90253497 |
47 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.88295536 |
48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.88106617 |
49 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87037550 |
50 | Nicotine addiction_Homo sapiens_hsa05033 | 0.87002463 |
51 | Galactose metabolism_Homo sapiens_hsa00052 | 0.86487756 |
52 | Carbon metabolism_Homo sapiens_hsa01200 | 0.82460235 |
53 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.82231827 |
54 | Phototransduction_Homo sapiens_hsa04744 | 0.81582755 |
55 | Parkinsons disease_Homo sapiens_hsa05012 | 0.81520973 |
56 | Purine metabolism_Homo sapiens_hsa00230 | 0.75365001 |
57 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.75046159 |
58 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74650001 |
59 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.72750497 |
60 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71019520 |
61 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.70329944 |
62 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.69618593 |
63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68576231 |
64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.66289024 |
65 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.65835889 |
66 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.65722907 |
67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.65537296 |
68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.65342741 |
69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.64108693 |
70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.62408783 |
71 | Thyroid cancer_Homo sapiens_hsa05216 | 0.60115556 |
72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.59584583 |
73 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.59010075 |
74 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.58561352 |
75 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.55888553 |
76 | Taste transduction_Homo sapiens_hsa04742 | 0.54597679 |
77 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.52796103 |
78 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51795158 |
79 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51367953 |
80 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.51098656 |
81 | Lysine degradation_Homo sapiens_hsa00310 | 0.50546771 |
82 | Adherens junction_Homo sapiens_hsa04520 | 0.50200741 |
83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49913169 |
84 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.48783343 |
85 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.48423017 |
86 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.48344980 |
87 | Tight junction_Homo sapiens_hsa04530 | 0.47449316 |
88 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46053433 |
89 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.44975824 |
90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44533233 |
91 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.43313552 |
92 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.43162658 |
93 | Bladder cancer_Homo sapiens_hsa05219 | 0.41067063 |
94 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.40041004 |
95 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39257305 |
96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38759253 |
97 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.38532129 |
98 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.37940610 |
99 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.37209735 |
100 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35841427 |
101 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.34827195 |
102 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.33842159 |
103 | HTLV-I infection_Homo sapiens_hsa05166 | 0.31297632 |
104 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30788064 |
105 | Colorectal cancer_Homo sapiens_hsa05210 | 0.29720847 |
106 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.29593375 |
107 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.29342376 |
108 | Alzheimers disease_Homo sapiens_hsa05010 | 0.28913798 |
109 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.28214714 |
110 | Melanoma_Homo sapiens_hsa05218 | 0.26690377 |
111 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.26318033 |
112 | Pathways in cancer_Homo sapiens_hsa05200 | 0.26247024 |
113 | Shigellosis_Homo sapiens_hsa05131 | 0.26006032 |
114 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.25860791 |
115 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.25175615 |
116 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.25108830 |
117 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.24611225 |
118 | Metabolic pathways_Homo sapiens_hsa01100 | 0.23953026 |
119 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23273015 |
120 | Huntingtons disease_Homo sapiens_hsa05016 | 0.23031428 |
121 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.22524336 |
122 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.22417552 |
123 | Other glycan degradation_Homo sapiens_hsa00511 | 0.21855610 |
124 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.20781523 |
125 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.19439376 |
126 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.15859762 |
127 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.15680370 |
128 | Legionellosis_Homo sapiens_hsa05134 | 0.14427962 |
129 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.13817970 |
130 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.13656441 |
131 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.13582719 |
132 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.12134099 |
133 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10611406 |
134 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.09527612 |
135 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.09142539 |
136 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.08597660 |