PRDM15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.59834384
2meiotic chromosome segregation (GO:0045132)4.05796759
3regulation of gamma-delta T cell activation (GO:0046643)4.03841104
4regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.01163881
5somatic diversification of immune receptors via somatic mutation (GO:0002566)3.95046426
6somatic hypermutation of immunoglobulin genes (GO:0016446)3.95046426
7snRNA transcription (GO:0009301)3.86862416
8cytoplasmic mRNA processing body assembly (GO:0033962)3.79738163
9negative regulation of cell killing (GO:0031342)3.77948994
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.77948994
11ribosomal small subunit assembly (GO:0000028)3.76123750
12mature B cell differentiation (GO:0002335)3.53756437
13regulation of gamma-delta T cell differentiation (GO:0045586)3.51134540
14regulation of histone H3-K27 methylation (GO:0061085)3.47532690
15regulation of B cell receptor signaling pathway (GO:0050855)3.44706154
16regulation of nuclear cell cycle DNA replication (GO:0033262)3.44281863
17DNA replication checkpoint (GO:0000076)3.36645593
18positive regulation by host of viral transcription (GO:0043923)3.30536902
19mitotic sister chromatid cohesion (GO:0007064)3.21671523
20monoubiquitinated protein deubiquitination (GO:0035520)3.21209485
21interferon-gamma production (GO:0032609)3.19418383
22mature B cell differentiation involved in immune response (GO:0002313)3.17493197
23nuclear pore complex assembly (GO:0051292)3.16736471
24peptidyl-lysine methylation (GO:0018022)3.11269984
25NIK/NF-kappaB signaling (GO:0038061)3.08736728
26regulation of MHC class I biosynthetic process (GO:0045343)3.06093197
27histone H3-K4 methylation (GO:0051568)3.06065443
28regulation of establishment of cell polarity (GO:2000114)3.05858114
29histone H3-K4 trimethylation (GO:0080182)3.05041329
30histone H3-K9 modification (GO:0061647)3.04607206
31positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.04543456
32negative T cell selection (GO:0043383)3.03251743
33DNA alkylation (GO:0006305)2.99136733
34DNA methylation (GO:0006306)2.99136733
35antigen processing and presentation via MHC class Ib (GO:0002475)2.94662557
36B cell proliferation (GO:0042100)2.94340098
37DNA replication initiation (GO:0006270)2.94295768
38B cell receptor signaling pathway (GO:0050853)2.93458365
39T cell lineage commitment (GO:0002360)2.88738469
40positive regulation of developmental pigmentation (GO:0048087)2.86313052
41positive regulation of protein homooligomerization (GO:0032464)2.85144062
42positive regulation of humoral immune response (GO:0002922)2.82687691
43positive regulation of interleukin-1 beta secretion (GO:0050718)2.81230956
44positive T cell selection (GO:0043368)2.81119471
45interkinetic nuclear migration (GO:0022027)2.80799105
46positive regulation of granulocyte differentiation (GO:0030854)2.80555559
47nuclear pore organization (GO:0006999)2.79164116
48positive regulation of DNA-templated transcription, initiation (GO:2000144)2.77792664
49double-strand break repair via homologous recombination (GO:0000724)2.77673179
50definitive hemopoiesis (GO:0060216)2.77238272
51somatic diversification of immunoglobulins (GO:0016445)2.77213700
52response to interleukin-15 (GO:0070672)2.76361551
53regulation of DNA endoreduplication (GO:0032875)2.76157189
54T cell homeostasis (GO:0043029)2.75849546
55reciprocal meiotic recombination (GO:0007131)2.75044371
56reciprocal DNA recombination (GO:0035825)2.75044371
57regulation of centriole replication (GO:0046599)2.75014095
58negative thymic T cell selection (GO:0045060)2.74899700
59histone H3-K36 demethylation (GO:0070544)2.73921736
60DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.73851054
61somatic diversification of immune receptors (GO:0002200)2.73312255
62DNA strand elongation involved in DNA replication (GO:0006271)2.72845210
63positive regulation of B cell differentiation (GO:0045579)2.72278711
64tolerance induction (GO:0002507)2.70999438
65regulation of hippo signaling (GO:0035330)2.70804118
66recombinational repair (GO:0000725)2.70386755
67N-terminal protein amino acid acetylation (GO:0006474)2.70378316
68sister chromatid cohesion (GO:0007062)2.69563983
69DNA methylation or demethylation (GO:0044728)2.69269268
70positive regulation of histone H3-K4 methylation (GO:0051571)2.69022769
71histone H2A acetylation (GO:0043968)2.68442503
72positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.68406113
73negative regulation of interleukin-12 production (GO:0032695)2.68200883
74telomere maintenance via recombination (GO:0000722)2.67929921
75replication fork processing (GO:0031297)2.67702225
76kinetochore organization (GO:0051383)2.67512272
77DNA duplex unwinding (GO:0032508)2.67298098
78positive regulation of mitotic sister chromatid separation (GO:1901970)2.66763833
79positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.66763833
80positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.66763833
81histone H4-K16 acetylation (GO:0043984)2.66733834
82regulation of telomere maintenance (GO:0032204)2.65099605
83phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.65053196
84regulation of centrosome duplication (GO:0010824)2.64878853
85DNA double-strand break processing (GO:0000729)2.64843077
86mitotic sister chromatid segregation (GO:0000070)2.64018763
87DNA geometric change (GO:0032392)2.63972257
88maturation of 5.8S rRNA (GO:0000460)2.62487380
89non-recombinational repair (GO:0000726)2.62381167
90double-strand break repair via nonhomologous end joining (GO:0006303)2.62381167
91positive regulation of CREB transcription factor activity (GO:0032793)2.62055475
92spliceosomal tri-snRNP complex assembly (GO:0000244)2.61430335
93facial nerve structural organization (GO:0021612)2.61037328
94T-helper cell differentiation (GO:0042093)2.59808122
95CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.59808122
96positive regulation of mRNA catabolic process (GO:0061014)2.59595304
97regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.59461987
98positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.59461987
99rRNA catabolic process (GO:0016075)2.59139889
100B cell homeostasis (GO:0001782)2.59054705
101DNA strand elongation (GO:0022616)2.57713959
102mitotic recombination (GO:0006312)2.57643900
103defense response to protozoan (GO:0042832)2.57447280
104histone deubiquitination (GO:0016578)2.57249884
105regulation of B cell differentiation (GO:0045577)2.57235055
106sister chromatid segregation (GO:0000819)2.56601544
107T cell selection (GO:0045058)2.55146892
108positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.54738032
109replicative senescence (GO:0090399)2.54410558
110negative regulation of DNA-dependent DNA replication (GO:2000104)2.51951916
111positive regulation of interleukin-1 secretion (GO:0050716)2.51799871
112antigen receptor-mediated signaling pathway (GO:0050851)2.51780629
113myeloid dendritic cell activation (GO:0001773)2.51433216
114negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.50552712
115negative regulation of translation, ncRNA-mediated (GO:0040033)2.50552712
116regulation of translation, ncRNA-mediated (GO:0045974)2.50552712
117kinetochore assembly (GO:0051382)2.50021798
118cellular response to interleukin-15 (GO:0071350)2.49276960
119megakaryocyte development (GO:0035855)2.48768744
120T cell receptor signaling pathway (GO:0050852)2.47377939
121regulation of pigment cell differentiation (GO:0050932)2.46770949
122CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.45780077
123negative regulation of T cell mediated immunity (GO:0002710)2.45580554
124mast cell activation (GO:0045576)2.44900323
125alpha-beta T cell differentiation (GO:0046632)2.43371236
126alpha-beta T cell activation (GO:0046631)2.43028954
127lymphocyte homeostasis (GO:0002260)2.42542634
128G-protein coupled receptor internalization (GO:0002031)2.39032178
129T cell differentiation (GO:0030217)2.38387087
130peptidyl-lysine trimethylation (GO:0018023)2.38184144
131response to protozoan (GO:0001562)2.38030747
132embryonic hemopoiesis (GO:0035162)2.36423552
133negative regulation of histone methylation (GO:0031061)2.35896886
134detection of bacterium (GO:0016045)2.35433713
135regulation of interleukin-1 beta secretion (GO:0050706)2.34527707
136regulation of histone H3-K9 methylation (GO:0051570)2.32498366
137B cell differentiation (GO:0030183)2.31783920
138regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.31496633
139alpha-beta T cell differentiation involved in immune response (GO:0002293)2.31406931
140alpha-beta T cell activation involved in immune response (GO:0002287)2.31406931
141T cell differentiation involved in immune response (GO:0002292)2.31406931
142regulation of regulatory T cell differentiation (GO:0045589)2.30827299
143V(D)J recombination (GO:0033151)2.30043348
144maturation of SSU-rRNA (GO:0030490)2.29820867
145CD4-positive, alpha-beta T cell activation (GO:0035710)2.28707715
146mast cell degranulation (GO:0043303)2.26986198
147mast cell activation involved in immune response (GO:0002279)2.26986198
148regulation of histone H3-K4 methylation (GO:0051569)2.25705973
149CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.25058644
150histone lysine methylation (GO:0034968)2.23306660
151neutrophil activation (GO:0042119)2.23219629
152positive thymic T cell selection (GO:0045059)2.21110242
153histone methylation (GO:0016571)2.21020371
154histone H3-K9 methylation (GO:0051567)2.19444442
155germinal center formation (GO:0002467)2.18407482
156regulation of histone methylation (GO:0031060)2.18089787
157lymphocyte differentiation (GO:0030098)2.17434146
158thymic T cell selection (GO:0045061)2.17311978
159negative regulation of erythrocyte differentiation (GO:0045647)2.16715015
160regulation of T cell receptor signaling pathway (GO:0050856)2.15240329
161IMP biosynthetic process (GO:0006188)2.13539976
162leukocyte homeostasis (GO:0001776)2.13255886
163positive regulation of antigen processing and presentation (GO:0002579)2.13206928
164detection of other organism (GO:0098543)2.13132332

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.43227321
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.29067132
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.94949473
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.21164641
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.86290201
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.84968165
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.84131587
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.83244055
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.71059693
10MYC_22102868_ChIP-Seq_BL_Human2.63337122
11SCL_19346495_ChIP-Seq_HPC-7_Human2.61572754
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.59189915
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.49517276
14STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.49175089
15KDM5A_27292631_Chip-Seq_BREAST_Human2.37599916
16FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.35735245
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.31342463
18TP63_19390658_ChIP-ChIP_HaCaT_Human2.25041924
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.23312564
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.16752110
21NOTCH1_21737748_ChIP-Seq_TLL_Human2.10729613
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.09057280
23ZNF274_21170338_ChIP-Seq_K562_Hela2.06355453
24RUNX_20019798_ChIP-Seq_JUKART_Human2.06119914
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.03373564
26VDR_23849224_ChIP-Seq_CD4+_Human2.02242160
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.98175541
28MYB_26560356_Chip-Seq_TH2_Human1.94055015
29SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.90296894
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.90207405
31* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.85643038
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.81439527
33* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.80310453
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79808125
35IRF8_21731497_ChIP-ChIP_J774_Mouse1.78634636
36EST1_17652178_ChIP-ChIP_JURKAT_Human1.76559585
37RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.75034468
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.74978947
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.72680801
40MYB_26560356_Chip-Seq_TH1_Human1.72110660
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.67233058
42ETS1_20019798_ChIP-Seq_JURKAT_Human1.64794687
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64713955
44CIITA_25753668_ChIP-Seq_RAJI_Human1.61167821
45VDR_21846776_ChIP-Seq_THP-1_Human1.59934501
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.59351436
47E2F1_21310950_ChIP-Seq_MCF-7_Human1.57616366
48PCGF2_27294783_Chip-Seq_ESCs_Mouse1.55325870
49JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.54116855
50BP1_19119308_ChIP-ChIP_Hs578T_Human1.52659468
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.52644666
52* TCF7_22412390_ChIP-Seq_EML_Mouse1.52297335
53ELF1_17652178_ChIP-ChIP_JURKAT_Human1.50015180
54E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.48643575
55IRF8_27001747_Chip-Seq_BMDM_Mouse1.47968675
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.45760125
57* GABP_19822575_ChIP-Seq_HepG2_Human1.44562552
58UTX_26944678_Chip-Seq_JUKART_Human1.43998683
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.40344709
60E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40335034
61GBX2_23144817_ChIP-Seq_PC3_Human1.39919326
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39691021
63MAF_26560356_Chip-Seq_TH1_Human1.39617025
64MYB_21317192_ChIP-Seq_ERMYB_Mouse1.38642281
65SPI1_23547873_ChIP-Seq_NB4_Human1.36883685
66YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35896173
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.34882504
68GATA1_22025678_ChIP-Seq_K562_Human1.34733499
69VDR_24763502_ChIP-Seq_THP-1_Human1.33934915
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33924321
71FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.33709228
72RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.33423502
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.32487192
74PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31377262
75PCGF2_27294783_Chip-Seq_NPCs_Mouse1.29526598
76* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.29266623
77MYC_18940864_ChIP-ChIP_HL60_Human1.29044564
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28630307
79RUNX1_22412390_ChIP-Seq_EML_Mouse1.28588235
80DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.28238677
81IRF1_19129219_ChIP-ChIP_H3396_Human1.26776059
82NFE2_27457419_Chip-Seq_LIVER_Mouse1.24232147
83THAP11_20581084_ChIP-Seq_MESCs_Mouse1.23812036
84FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17406571
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17046372
86PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16950076
87PU_27001747_Chip-Seq_BMDM_Mouse1.16460200
88SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14319525
89CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10217406
90GATA3_26560356_Chip-Seq_TH2_Human1.09817998
91GABP_17652178_ChIP-ChIP_JURKAT_Human1.08429338
92MYC_18555785_ChIP-Seq_MESCs_Mouse1.06653329
93ELK1_19687146_ChIP-ChIP_HELA_Human1.06425577
94IGF1R_20145208_ChIP-Seq_DFB_Human1.05774307
95SMRT_27268052_Chip-Seq_Bcells_Human1.05408756
96* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.04346993
97EWS_26573619_Chip-Seq_HEK293_Human1.03524086
98ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02948552
99KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.02789523
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02651011
101DCP1A_22483619_ChIP-Seq_HELA_Human1.02396738
102SPI1_23127762_ChIP-Seq_K562_Human1.01344189
103TTF2_22483619_ChIP-Seq_HELA_Human1.01186733
104MAF_26560356_Chip-Seq_TH2_Human1.01004225
105HOXB4_20404135_ChIP-ChIP_EML_Mouse1.00191635
106KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00172029
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00126232
108* LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.99802365
109FOXP3_21729870_ChIP-Seq_TREG_Human0.99512140
110CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98320493
111SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96945633
112MYC_19030024_ChIP-ChIP_MESCs_Mouse0.96708244
113LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.94549020
114* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94455455
115* E2F1_17053090_ChIP-ChIP_MCF-7_Human0.93830043
116GATA3_27048872_Chip-Seq_THYMUS_Human0.93038773
117EZH2_27294783_Chip-Seq_NPCs_Mouse0.92188214
118POU3F2_20337985_ChIP-ChIP_501MEL_Human0.92096178
119NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.91310048
120TFEB_21752829_ChIP-Seq_HELA_Human0.91046733
121FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.90500711
122MYCN_18555785_ChIP-Seq_MESCs_Mouse0.89668193
123DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89400754
124XRN2_22483619_ChIP-Seq_HELA_Human0.89385683
125YY1_21170310_ChIP-Seq_MESCs_Mouse0.89132768
126BRD4_27068464_Chip-Seq_AML-cells_Mouse0.88301755
127FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.88120916
128PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87624741
129CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87537740
130GATA3_26560356_Chip-Seq_TH1_Human0.86420743
131NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.85312965
132POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.84077493
133VDR_22108803_ChIP-Seq_LS180_Human0.83682164
134HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.83406730
135KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.82591110
136TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.81955997
137LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81163824
138CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.80875933
139POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.80865084
140TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80865084
141MYC_19079543_ChIP-ChIP_MESCs_Mouse0.80397497
142IKZF1_21737484_ChIP-ChIP_HCT116_Human0.79015663
143MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.78263557
144P53_22387025_ChIP-Seq_ESCs_Mouse0.78200553
145POU5F1_16153702_ChIP-ChIP_HESCs_Human0.77304902
146E2F1_18555785_Chip-Seq_ESCs_Mouse0.75204875

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.07957146
2MP0005174_abnormal_tail_pigmentation3.63561146
3MP0000372_irregular_coat_pigmentation3.23856921
4MP0003763_abnormal_thymus_physiology2.80334657
5MP0000015_abnormal_ear_pigmentation2.78619027
6MP0002396_abnormal_hematopoietic_system2.77374038
7MP0006292_abnormal_olfactory_placode2.55695241
8MP0005671_abnormal_response_to2.43889994
9MP0001348_abnormal_lacrimal_gland2.36190348
10MP0001800_abnormal_humoral_immune2.31561214
11MP0001835_abnormal_antigen_presentation2.29556268
12MP0001188_hyperpigmentation2.15774015
13MP0002938_white_spotting2.11895289
14MP0004808_abnormal_hematopoietic_stem2.10854427
15MP0003787_abnormal_imprinting2.09823359
16MP0005075_abnormal_melanosome_morpholog2.09429645
17MP0002398_abnormal_bone_marrow2.05555371
18MP0003436_decreased_susceptibility_to2.03748467
19MP0001986_abnormal_taste_sensitivity2.03675767
20MP0009278_abnormal_bone_marrow1.96897719
21MP0002452_abnormal_antigen_presenting1.94677454
22MP0008058_abnormal_DNA_repair1.93774914
23MP0008057_abnormal_DNA_replication1.93495473
24MP0002420_abnormal_adaptive_immunity1.89714345
25MP0010094_abnormal_chromosome_stability1.89652739
26MP0009785_altered_susceptibility_to1.89549142
27MP0001819_abnormal_immune_cell1.86491671
28MP0002095_abnormal_skin_pigmentation1.85966258
29MP0003121_genomic_imprinting1.82351143
30MP0002723_abnormal_immune_serum1.77226825
31MP0005000_abnormal_immune_tolerance1.69498825
32MP0000703_abnormal_thymus_morphology1.68427449
33MP0000689_abnormal_spleen_morphology1.66647451
34MP0000716_abnormal_immune_system1.62662135
35MP0003077_abnormal_cell_cycle1.57348591
36MP0000371_diluted_coat_color1.57341264
37MP0005025_abnormal_response_to1.50694370
38MP0009333_abnormal_splenocyte_physiolog1.49646160
39MP0005083_abnormal_biliary_tract1.49564783
40MP0005310_abnormal_salivary_gland1.49064570
41MP0002722_abnormal_immune_system1.49057538
42MP0002419_abnormal_innate_immunity1.47832592
43MP0005409_darkened_coat_color1.46872662
44MP0005387_immune_system_phenotype1.45926471
45MP0001790_abnormal_immune_system1.45926471
46MP0002138_abnormal_hepatobiliary_system1.45615409
47MP0004510_myositis1.40477760
48MP0005397_hematopoietic_system_phenotyp1.38824765
49MP0001545_abnormal_hematopoietic_system1.38824765
50MP0005220_abnormal_exocrine_pancreas1.38515770
51MP0002429_abnormal_blood_cell1.37877265
52MP0003693_abnormal_embryo_hatching1.37560220
53MP0000685_abnormal_immune_system1.33279232
54MP0005171_absent_coat_pigmentation1.33183813
55MP0001873_stomach_inflammation1.32519280
56MP0003724_increased_susceptibility_to1.31723587
57MP0003183_abnormal_peptide_metabolism1.28962324
58MP0002405_respiratory_system_inflammati1.28370213
59MP0003646_muscle_fatigue1.26782129
60MP0003123_paternal_imprinting1.26151215
61MP0002006_tumorigenesis1.25215371
62MP0003111_abnormal_nucleus_morphology1.25211776
63MP0005464_abnormal_platelet_physiology1.25012676
64MP0008995_early_reproductive_senescence1.24151494
65MP0000490_abnormal_crypts_of1.22986563
66MP0008007_abnormal_cellular_replicative1.20499362
67MP0002277_abnormal_respiratory_mucosa1.19047732
68MP0002166_altered_tumor_susceptibility1.19030684
69MP0000427_abnormal_hair_cycle1.14201942
70MP0005408_hypopigmentation1.14003479
71MP0002075_abnormal_coat/hair_pigmentati1.13438296
72MP0003136_yellow_coat_color1.12201834
73MP0004381_abnormal_hair_follicle1.11142552
74MP0002089_abnormal_postnatal_growth/wei1.10043738
75MP0002148_abnormal_hypersensitivity_rea1.09942844
76MP0005379_endocrine/exocrine_gland_phen1.07881864
77MP0002933_joint_inflammation1.07639457
78MP0008789_abnormal_olfactory_epithelium1.02215359
79MP0001879_abnormal_lymphatic_vessel1.02195287
80MP0008877_abnormal_DNA_methylation1.01777424
81MP0008961_abnormal_basal_metabolism1.01105280
82MP0002163_abnormal_gland_morphology1.00496529
83MP0003303_peritoneal_inflammation1.00019451
84MP0010155_abnormal_intestine_physiology0.96811010
85MP0000465_gastrointestinal_hemorrhage0.93523160
86MP0002837_dystrophic_cardiac_calcinosis0.93161793
87MP0005394_taste/olfaction_phenotype0.92422038
88MP0005499_abnormal_olfactory_system0.92422038
89MP0001929_abnormal_gametogenesis0.92221336
90MP0003890_abnormal_embryonic-extraembry0.92033473
91MP0002877_abnormal_melanocyte_morpholog0.85053869
92MP0001730_embryonic_growth_arrest0.84982697
93MP0005266_abnormal_metabolism0.84608445
94MP0003943_abnormal_hepatobiliary_system0.83360356
95MP0000858_altered_metastatic_potential0.83092536
96MP0000383_abnormal_hair_follicle0.82734099
97MP0004233_abnormal_muscle_weight0.82670365
98MP0001186_pigmentation_phenotype0.82487112
99MP0000470_abnormal_stomach_morphology0.78768338
100MP0002019_abnormal_tumor_incidence0.78762634
101MP0001145_abnormal_male_reproductive0.78297407
102MP0001919_abnormal_reproductive_system0.76159440
103MP0001293_anophthalmia0.75964243
104MP0002102_abnormal_ear_morphology0.75394305
105MP0001845_abnormal_inflammatory_respons0.74791177
106MP0003698_abnormal_male_reproductive0.74401371
107MP0003718_maternal_effect0.73787898
108MP0002160_abnormal_reproductive_system0.72886711
109MP0002177_abnormal_outer_ear0.72349389
110MP0002693_abnormal_pancreas_physiology0.71843620
111MP0002088_abnormal_embryonic_growth/wei0.71252773
112MP0003984_embryonic_growth_retardation0.70915585
113MP0001672_abnormal_embryogenesis/_devel0.70482070
114MP0005380_embryogenesis_phenotype0.70482070
115MP0006035_abnormal_mitochondrial_morpho0.69908444
116MP0005451_abnormal_body_composition0.69517530
117MP0003567_abnormal_fetal_cardiomyocyte0.69437619
118MP0005389_reproductive_system_phenotype0.69373139
119MP0003786_premature_aging0.68963218
120MP0010307_abnormal_tumor_latency0.68445402
121MP0008872_abnormal_physiological_respon0.67908377
122MP0001697_abnormal_embryo_size0.67346005
123MP0001119_abnormal_female_reproductive0.67191011
124MP0003172_abnormal_lysosome_physiology0.66264284
125MP0005076_abnormal_cell_differentiation0.66155580
126MP0000350_abnormal_cell_proliferation0.65161542
127MP0000653_abnormal_sex_gland0.64154451
128MP0001661_extended_life_span0.63402028
129MP0002928_abnormal_bile_duct0.62623315
130MP0003866_abnormal_defecation0.62101987
131MP0002009_preneoplasia0.61801322
132MP0003315_abnormal_perineum_morphology0.61556201
133MP0001533_abnormal_skeleton_physiology0.61210190
134MP0005645_abnormal_hypothalamus_physiol0.60541502
135MP0004947_skin_inflammation0.60270729
136MP0004957_abnormal_blastocyst_morpholog0.59183595
137MP0004197_abnormal_fetal_growth/weight/0.59093051
138MP0000313_abnormal_cell_death0.56880325
139MP0002210_abnormal_sex_determination0.56871617

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)4.63318871
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.16819804
3Chromsome breakage (HP:0040012)3.72318791
4Chronic hepatic failure (HP:0100626)3.49906734
5Hyperventilation (HP:0002883)3.33160809
6T lymphocytopenia (HP:0005403)3.11004765
7Genetic anticipation (HP:0003743)3.06720539
8Birth length less than 3rd percentile (HP:0003561)3.01384196
9Abnormality of the fingertips (HP:0001211)2.98092776
10Abnormality of T cell number (HP:0011839)2.95176998
11Gaze-evoked nystagmus (HP:0000640)2.95013881
12Abnormality of DNA repair (HP:0003254)2.94711223
13Squamous cell carcinoma (HP:0002860)2.94681376
14Fair hair (HP:0002286)2.77990562
15Prominent nose (HP:0000448)2.72023479
16Dysmetric saccades (HP:0000641)2.69112677
17Thyroiditis (HP:0100646)2.63681512
18Panhypogammaglobulinemia (HP:0003139)2.60325258
19Reticulocytopenia (HP:0001896)2.57894797
20Clubbing of toes (HP:0100760)2.56518705
21Aplasia/Hypoplasia of the uvula (HP:0010293)2.55828081
22Abnormality of chromosome stability (HP:0003220)2.54471537
23Gastrointestinal stroma tumor (HP:0100723)2.53297841
24Progressive inability to walk (HP:0002505)2.52209628
25Meckel diverticulum (HP:0002245)2.51401064
26Duplicated collecting system (HP:0000081)2.49220149
27Volvulus (HP:0002580)2.49069961
28Clumsiness (HP:0002312)2.48149544
29Generalized hypopigmentation of hair (HP:0011358)2.47870996
30Abnormality of the renal collecting system (HP:0004742)2.47474151
31Abnormality of the ileum (HP:0001549)2.44574461
32Neoplasm of the adrenal cortex (HP:0100641)2.44400290
33Sloping forehead (HP:0000340)2.42162624
34Mediastinal lymphadenopathy (HP:0100721)2.41941762
35Recurrent viral infections (HP:0004429)2.40774582
36Attenuation of retinal blood vessels (HP:0007843)2.40070965
37Acute lymphatic leukemia (HP:0006721)2.39646611
38Partial agenesis of the corpus callosum (HP:0001338)2.38809697
39Protruding tongue (HP:0010808)2.38375816
40Patellar aplasia (HP:0006443)2.36766717
41Recurrent fungal infections (HP:0002841)2.35605768
42Abnormality of the preputium (HP:0100587)2.35414535
43Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.34348607
44Pancreatic cysts (HP:0001737)2.32118800
45Myelodysplasia (HP:0002863)2.31478915
46Prolonged bleeding time (HP:0003010)2.30956878
47Agammaglobulinemia (HP:0004432)2.28980243
48Abnormality of B cell number (HP:0010975)2.28949334
49B lymphocytopenia (HP:0010976)2.28949334
50Congenital stationary night blindness (HP:0007642)2.28116248
51Syringomyelia (HP:0003396)2.25551958
52Spinal cord lesions (HP:0100561)2.25551958
53Viral hepatitis (HP:0006562)2.25026760
54Meningitis (HP:0001287)2.21181316
55Peripheral hypomyelination (HP:0007182)2.20470962
56Aplasia/Hypoplasia of the patella (HP:0006498)2.20275711
57Basal cell carcinoma (HP:0002671)2.17943314
58Recurrent sinusitis (HP:0011108)2.17762100
59Abnormal delayed hypersensitivity skin test (HP:0002963)2.17474606
60Albinism (HP:0001022)2.17090953
61Lymphopenia (HP:0001888)2.16712095
62Urethral obstruction (HP:0000796)2.14868932
63Absent frontal sinuses (HP:0002688)2.14091300
64Thrombocytosis (HP:0001894)2.12502344
65Abnormality of the carotid arteries (HP:0005344)2.12412541
66Recurrent abscess formation (HP:0002722)2.12135261
67Mesomelia (HP:0003027)2.10935728
68Prostate neoplasm (HP:0100787)2.10713314
69Ectopic kidney (HP:0000086)2.09874137
70Acute myeloid leukemia (HP:0004808)2.07875458
71IgG deficiency (HP:0004315)2.04130273
72Poikiloderma (HP:0001029)2.03826920
73Myositis (HP:0100614)2.03034342
74Abnormality of T cells (HP:0002843)1.99966367
75Molar tooth sign on MRI (HP:0002419)1.99599486
76Abnormality of midbrain morphology (HP:0002418)1.99599486
77Short thumb (HP:0009778)1.98125135
78Limb hypertonia (HP:0002509)1.97833414
79Cutaneous melanoma (HP:0012056)1.97678919
80Abnormality of the prostate (HP:0008775)1.97283758
81Retrobulbar optic neuritis (HP:0100654)1.96364160
82Optic neuritis (HP:0100653)1.96364160
83Horseshoe kidney (HP:0000085)1.94937104
84Cafe-au-lait spot (HP:0000957)1.94792260
85Abnormality of cells of the lymphoid lineage (HP:0012140)1.94100058
86Cellulitis (HP:0100658)1.92787942
87Colitis (HP:0002583)1.92104024
88Abnormality of the renal cortex (HP:0011035)1.90124543
89Cerebellar dysplasia (HP:0007033)1.89859535
90Progressive cerebellar ataxia (HP:0002073)1.89738114
91Autoimmune thrombocytopenia (HP:0001973)1.87624050
92Periodontitis (HP:0000704)1.87540601
93Stomatitis (HP:0010280)1.87416782
94Eczematoid dermatitis (HP:0000976)1.86679956
95Truncal obesity (HP:0001956)1.86613338
96Pancreatic fibrosis (HP:0100732)1.86608061
97Papilloma (HP:0012740)1.86428043
98Verrucae (HP:0200043)1.86428043
99Obstructive lung disease (HP:0006536)1.86262192
100Chronic obstructive pulmonary disease (HP:0006510)1.86262192
101Inability to walk (HP:0002540)1.86180705
102Impulsivity (HP:0100710)1.86046128
103Sandal gap (HP:0001852)1.85942719
104Premature ovarian failure (HP:0008209)1.85817673
105Generalized hypopigmentation (HP:0007513)1.85022121
106Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.84439702
107Short 4th metacarpal (HP:0010044)1.84439702
108Pendular nystagmus (HP:0012043)1.83482167
109Tubular atrophy (HP:0000092)1.82945580
110Hyperacusis (HP:0010780)1.82695254
111Chronic mucocutaneous candidiasis (HP:0002728)1.81796242
112Recurrent cutaneous fungal infections (HP:0011370)1.81796242
113Cutis marmorata (HP:0000965)1.81551883
114IgA deficiency (HP:0002720)1.80725526
115Amaurosis fugax (HP:0100576)1.80558467
116Febrile seizures (HP:0002373)1.80357050
117Nephronophthisis (HP:0000090)1.80256360
118Microvesicular hepatic steatosis (HP:0001414)1.79258609
119Supernumerary spleens (HP:0009799)1.79248572
120Abnormality of T cell physiology (HP:0011840)1.78990692
121Lymphoma (HP:0002665)1.78853453
122Lip pit (HP:0100267)1.78468067
123Abnormal lung lobation (HP:0002101)1.78247550
124Ocular albinism (HP:0001107)1.77516526
125Oligodactyly (hands) (HP:0001180)1.77267369
126Combined immunodeficiency (HP:0005387)1.77201474
127Submucous cleft hard palate (HP:0000176)1.76330972
128Absent thumb (HP:0009777)1.75959700
129Duodenal stenosis (HP:0100867)1.73399894
130Small intestinal stenosis (HP:0012848)1.73399894
131Depressed nasal tip (HP:0000437)1.72847065
132Obsessive-compulsive behavior (HP:0000722)1.72569477
133Hypergonadotropic hypogonadism (HP:0000815)1.71543060
134Optic nerve coloboma (HP:0000588)1.71192285
135Eosinophilia (HP:0001880)1.70546117
136Hypopigmentation of the fundus (HP:0007894)1.69334075
137Smooth philtrum (HP:0000319)1.69120175
138Hypoplasia of the thymus (HP:0000778)1.68490619
139Hypoplasia of the pons (HP:0012110)1.68419184
140Long nose (HP:0003189)1.68326292
141Inflammation of the large intestine (HP:0002037)1.68145333
142Absent rod-and cone-mediated responses on ERG (HP:0007688)1.67916717
143Gastrointestinal inflammation (HP:0004386)1.66559591
144Severe visual impairment (HP:0001141)1.66557003
145Severe combined immunodeficiency (HP:0004430)1.66072718
146Vasculitis (HP:0002633)1.65439128
147Tented upper lip vermilion (HP:0010804)1.63624927
148Heterotopia (HP:0002282)1.63441787
149Recurrent bronchitis (HP:0002837)1.62631780
150Medulloblastoma (HP:0002885)1.62555444
151Recurrent bacterial skin infections (HP:0005406)1.62418979
152Encephalitis (HP:0002383)1.59208618
153Nonprogressive disorder (HP:0003680)1.58704622
154Abnormality of the columella (HP:0009929)1.57763577
155Keratitis (HP:0000491)1.57375089
156Abnormality of the nasal septum (HP:0000419)1.57180254
157Ureteral stenosis (HP:0000071)1.56881057
158Abnormality of the phalanges of the hallux (HP:0010057)1.56548532
159Ureteral obstruction (HP:0006000)1.55545285
160Elevated erythrocyte sedimentation rate (HP:0003565)1.54557210

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.64619686
2TXK3.61856468
3CASK2.84424433
4JAK32.70765511
5MKNK22.70023805
6SRPK12.61676055
7SIK32.58204563
8SIK22.43982579
9MAP3K142.31242396
10SMG12.25938494
11PRPF4B2.17338099
12CLK12.13326715
13FRK1.96666001
14MAPK111.90858354
15TNIK1.90542086
16CAMK1G1.81858127
17RIPK41.79252195
18ICK1.74109133
19BRD41.73751519
20CDK121.72153684
21CSF1R1.66193732
22MKNK11.64284925
23NLK1.61892039
24TLK11.60554531
25YES11.53321669
26PASK1.50365211
27BTK1.45817243
28ACVR1B1.44316395
29MAPKAPK31.40171194
30CDK41.37721710
31TAF11.33443334
32MAP3K71.33040484
33ZAP701.33018933
34TAOK31.30933234
35MUSK1.30905958
36EEF2K1.29345619
37BMPR1B1.28461134
38EIF2AK21.26469772
39TEC1.24000691
40CDC71.22992196
41LCK1.22531477
42IKBKE1.21415429
43IKBKB1.21247966
44MAP3K101.18058831
45TRIB31.17603253
46IRAK41.16586265
47NUAK11.15797523
48EIF2AK31.15087181
49ERN11.14051240
50CHUK1.14038255
51SYK1.13631387
52CHEK21.13535118
53TYK21.08647790
54KIT1.06887355
55ATR1.04524693
56HCK1.01766273
57CDK91.01139628
58FGR0.98811825
59AKT30.95213663
60NME10.93662744
61MARK30.89741525
62STK160.88118472
63MTOR0.88115091
64PIM10.85940063
65ERBB30.83853861
66INSRR0.83766431
67BLK0.83126654
68CAMKK10.82832423
69FES0.82768867
70LYN0.82127069
71WEE10.81936719
72PLK40.79624677
73HIPK20.78645800
74SGK30.78185322
75CDC42BPA0.78025290
76MARK20.76658728
77PDK20.71634278
78MAP2K70.71331349
79TGFBR10.68956473
80FGFR30.68916392
81TGFBR20.68560011
82SGK20.68554025
83TNK20.67500307
84MAP3K90.67204668
85JAK10.67182466
86MAP2K20.67009118
87STK40.65847131
88PRKD20.64829972
89PIK3CA0.63928566
90STK240.63741555
91CHEK10.63612459
92ADRBK20.63601344
93PRKAA10.63456631
94RPS6KA40.62442093
95ATM0.61629501
96RPS6KA60.61605033
97RPS6KB20.61017735
98NEK60.60893628
99STK38L0.60892631
100PRKCI0.59962605
101PIM20.59788112
102TAOK20.59776492
103MAPK120.59278891
104CDK80.57999309
105VRK10.57367976
106DYRK30.54515102
107ZAK0.54135795
108CSNK1A1L0.54080598
109TRPM70.54043710
110MAPKAPK50.53832586
111STK110.53543597
112PNCK0.53242279
113NME20.52322029
114RAF10.51626399
115ALK0.51029484
116RPS6KA50.50963503
117RPS6KA10.50660479
118ITK0.50605233
119CDK70.50449576
120CDK10.50107481
121CDK30.49435694
122MAP2K30.49160684
123SIK10.49110849
124RIPK10.47885733
125CDK60.47704950
126PAK20.47684107
127CSK0.47338458
128NEK20.46650920
129PRKCQ0.45948892
130CDK20.45739199
131CAMK40.45319291
132RPS6KB10.44953264
133PLK10.44398015
134MAP3K130.43745138
135CAMK1D0.43056824
136PRKAA20.42704472
137CSNK1G10.42297569
138TSSK60.42229401
139MELK0.41420707
140MAPK130.40815970
141STK30.40754632
142GSK3B0.40740768
143MAP3K40.40225348
144GRK10.39656873
145MAPK140.39637808
146AURKB0.39557419
147STK100.39022112
148MAP3K60.38494751
149PIK3CG0.37843478
150BMPR20.37833996
151RPS6KC10.36604053

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.34906074
2RNA polymerase_Homo sapiens_hsa030202.09545626
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.05741644
4B cell receptor signaling pathway_Homo sapiens_hsa046621.82206810
5Fanconi anemia pathway_Homo sapiens_hsa034601.80363326
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.68997312
7T cell receptor signaling pathway_Homo sapiens_hsa046601.67142578
8NOD-like receptor signaling pathway_Homo sapiens_hsa046211.66311997
9Measles_Homo sapiens_hsa051621.61020497
10Hematopoietic cell lineage_Homo sapiens_hsa046401.60286399
11Selenocompound metabolism_Homo sapiens_hsa004501.59437978
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.59091547
13DNA replication_Homo sapiens_hsa030301.57496960
14Herpes simplex infection_Homo sapiens_hsa051681.47495415
15Spliceosome_Homo sapiens_hsa030401.45319821
16Leishmaniasis_Homo sapiens_hsa051401.39240554
17Homologous recombination_Homo sapiens_hsa034401.38998484
18Folate biosynthesis_Homo sapiens_hsa007901.38990386
19Osteoclast differentiation_Homo sapiens_hsa043801.37737609
20RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.36563000
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.34546931
22Autoimmune thyroid disease_Homo sapiens_hsa053201.32909257
23Acute myeloid leukemia_Homo sapiens_hsa052211.32071311
24mRNA surveillance pathway_Homo sapiens_hsa030151.30923822
25Allograft rejection_Homo sapiens_hsa053301.30246883
26Graft-versus-host disease_Homo sapiens_hsa053321.28664641
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.22575484
28TNF signaling pathway_Homo sapiens_hsa046681.21908719
29Influenza A_Homo sapiens_hsa051641.18618999
30Legionellosis_Homo sapiens_hsa051341.18236132
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.17085124
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.15568477
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.15214285
34Transcriptional misregulation in cancer_Homo sapiens_hsa052021.13629606
35Non-homologous end-joining_Homo sapiens_hsa034501.13576308
36Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.13433637
37Toll-like receptor signaling pathway_Homo sapiens_hsa046201.12918870
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.10481642
39mTOR signaling pathway_Homo sapiens_hsa041501.08744790
40Hepatitis B_Homo sapiens_hsa051611.08352130
41Colorectal cancer_Homo sapiens_hsa052101.05160183
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02811458
43Mismatch repair_Homo sapiens_hsa034301.01141964
44Chemokine signaling pathway_Homo sapiens_hsa040621.00518532
45Longevity regulating pathway - mammal_Homo sapiens_hsa042111.00198969
46ABC transporters_Homo sapiens_hsa020100.99821303
47Ribosome_Homo sapiens_hsa030100.98583010
48Type I diabetes mellitus_Homo sapiens_hsa049400.98581901
49Base excision repair_Homo sapiens_hsa034100.98572749
50Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95043170
51Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.94937893
52Cell cycle_Homo sapiens_hsa041100.94216684
53Chronic myeloid leukemia_Homo sapiens_hsa052200.91804277
54Ovarian steroidogenesis_Homo sapiens_hsa049130.90981613
55Salmonella infection_Homo sapiens_hsa051320.90453093
56HTLV-I infection_Homo sapiens_hsa051660.88200085
57RNA degradation_Homo sapiens_hsa030180.86260397
58Systemic lupus erythematosus_Homo sapiens_hsa053220.85615373
59Antigen processing and presentation_Homo sapiens_hsa046120.84483621
60Viral carcinogenesis_Homo sapiens_hsa052030.83835213
61Dorso-ventral axis formation_Homo sapiens_hsa043200.83414074
62Toxoplasmosis_Homo sapiens_hsa051450.83164856
63Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.81973076
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81293100
65Butanoate metabolism_Homo sapiens_hsa006500.81264866
66AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81200669
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.81190271
68African trypanosomiasis_Homo sapiens_hsa051430.80640905
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.80338131
70MicroRNAs in cancer_Homo sapiens_hsa052060.80298762
71Non-small cell lung cancer_Homo sapiens_hsa052230.80074492
72Asthma_Homo sapiens_hsa053100.78459719
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78250931
74Basal transcription factors_Homo sapiens_hsa030220.77494062
75FoxO signaling pathway_Homo sapiens_hsa040680.77416423
76Malaria_Homo sapiens_hsa051440.76426540
77Endometrial cancer_Homo sapiens_hsa052130.74898256
78Purine metabolism_Homo sapiens_hsa002300.74737525
79Apoptosis_Homo sapiens_hsa042100.74692991
80Olfactory transduction_Homo sapiens_hsa047400.74343196
81Epstein-Barr virus infection_Homo sapiens_hsa051690.73727482
82Prolactin signaling pathway_Homo sapiens_hsa049170.73331892
83Hepatitis C_Homo sapiens_hsa051600.73032955
84RNA transport_Homo sapiens_hsa030130.73005308
85Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71936925
86Linoleic acid metabolism_Homo sapiens_hsa005910.71406807
87Platelet activation_Homo sapiens_hsa046110.71345072
88Small cell lung cancer_Homo sapiens_hsa052220.71342333
89Sulfur relay system_Homo sapiens_hsa041220.69951681
90Notch signaling pathway_Homo sapiens_hsa043300.68478114
91Prostate cancer_Homo sapiens_hsa052150.68064862
92Nucleotide excision repair_Homo sapiens_hsa034200.66033046
93Taste transduction_Homo sapiens_hsa047420.65970792
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.61906912
95Phototransduction_Homo sapiens_hsa047440.61279801
96Shigellosis_Homo sapiens_hsa051310.61276708
97Viral myocarditis_Homo sapiens_hsa054160.61256875
98p53 signaling pathway_Homo sapiens_hsa041150.60853007
99Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.60788692
100Tuberculosis_Homo sapiens_hsa051520.60225154
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58574411
102Pancreatic cancer_Homo sapiens_hsa052120.58137129
103Bladder cancer_Homo sapiens_hsa052190.57850165
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57097511
105Type II diabetes mellitus_Homo sapiens_hsa049300.57065009
106Lysine degradation_Homo sapiens_hsa003100.56945131
107Insulin resistance_Homo sapiens_hsa049310.54685954
108Pyrimidine metabolism_Homo sapiens_hsa002400.53168217
109Morphine addiction_Homo sapiens_hsa050320.53124362
110Inositol phosphate metabolism_Homo sapiens_hsa005620.52410261
111Pathways in cancer_Homo sapiens_hsa052000.51610594
112ErbB signaling pathway_Homo sapiens_hsa040120.51142532
113One carbon pool by folate_Homo sapiens_hsa006700.50820404
114Thyroid cancer_Homo sapiens_hsa052160.50756543
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50438157
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50307084
117MAPK signaling pathway_Homo sapiens_hsa040100.49862905
118Alcoholism_Homo sapiens_hsa050340.49628635
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49036132
120Melanoma_Homo sapiens_hsa052180.42658566
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40727183
122Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39530562
123Ether lipid metabolism_Homo sapiens_hsa005650.38593753
124Aldosterone synthesis and secretion_Homo sapiens_hsa049250.37598797
125Maturity onset diabetes of the young_Homo sapiens_hsa049500.35128392

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