PRG3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mucosal immune response (GO:0002385)9.84368047
2organ or tissue specific immune response (GO:0002251)9.19693019
3positive regulation of interleukin-4 production (GO:0032753)8.40412666
4protoporphyrinogen IX metabolic process (GO:0046501)8.19313788
5regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)8.06468225
6regulation of dendritic cell antigen processing and presentation (GO:0002604)8.01844669
7eosinophil migration (GO:0072677)7.90625549
8peptide catabolic process (GO:0043171)7.81208673
9protoporphyrinogen IX biosynthetic process (GO:0006782)7.76542875
10gas transport (GO:0015669)7.22503553
11detection of bacterium (GO:0016045)6.92142751
12hydrogen peroxide catabolic process (GO:0042744)6.55796020
13detection of other organism (GO:0098543)6.53851875
14regulation of T-helper 1 cell differentiation (GO:0045625)6.53608016
15myeloid dendritic cell differentiation (GO:0043011)6.47923392
16hemoglobin metabolic process (GO:0020027)6.09714412
17intracellular estrogen receptor signaling pathway (GO:0030520)6.04959330
18cell killing (GO:0001906)6.04726757
19regulation of interleukin-4 production (GO:0032673)6.00981105
20regulation of lipoprotein particle clearance (GO:0010984)6.00404089
21dendritic cell differentiation (GO:0097028)5.99824459
22* imidazole-containing compound metabolic process (GO:0052803)5.83429087
23myeloid dendritic cell activation (GO:0001773)5.69870250
24negative regulation of interleukin-8 production (GO:0032717)5.68632388
25defense response to Gram-positive bacterium (GO:0050830)5.65834790
26positive regulation of receptor biosynthetic process (GO:0010870)5.59745701
27defense response to fungus (GO:0050832)5.43146799
28porphyrin-containing compound biosynthetic process (GO:0006779)5.42947598
29positive regulation of antigen processing and presentation (GO:0002579)5.31605011
30negative regulation of growth of symbiont in host (GO:0044130)5.22583606
31negative regulation of growth of symbiont involved in interaction with host (GO:0044146)5.22583606
32modulation of growth of symbiont involved in interaction with host (GO:0044144)5.22583606
33regulation of growth of symbiont in host (GO:0044126)5.22583606
34respiratory burst (GO:0045730)5.08156225
35disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.92441575
36killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.92441575
37regulation of antigen processing and presentation (GO:0002577)4.81322329
38regulation of female gonad development (GO:2000194)4.80591460
39heme biosynthetic process (GO:0006783)4.73302317
40tetrapyrrole biosynthetic process (GO:0033014)4.72141525
41response to fungus (GO:0009620)4.71221208
42pentose-phosphate shunt (GO:0006098)4.67338875
43positive regulation of Cdc42 GTPase activity (GO:0043089)4.65892251
44erythrocyte maturation (GO:0043249)4.65684049
45regulation of interleukin-5 production (GO:0032674)4.60030736
46positive regulation of T-helper cell differentiation (GO:0045624)4.57353036
47sequestering of metal ion (GO:0051238)4.50054360
48positive regulation of neutrophil chemotaxis (GO:0090023)4.46087888
49positive regulation of neutrophil migration (GO:1902624)4.46087888
50leukocyte migration involved in inflammatory response (GO:0002523)4.45719707
51dendritic cell chemotaxis (GO:0002407)4.42507003
52positive regulation of granulocyte chemotaxis (GO:0071624)4.38893088
53positive regulation of glycoprotein biosynthetic process (GO:0010560)4.37298848
54defense response to bacterium (GO:0042742)4.30414604
55NADPH regeneration (GO:0006740)4.29681273
56porphyrin-containing compound metabolic process (GO:0006778)4.28528495
57oxygen transport (GO:0015671)4.27919640
58positive regulation of T-helper 1 type immune response (GO:0002827)4.26787430
59regulation of interleukin-10 production (GO:0032653)4.26251081
60hydrogen peroxide metabolic process (GO:0042743)4.25572029
61response to methylmercury (GO:0051597)4.21468947
62leukocyte aggregation (GO:0070486)4.18355197
63regulation of natural killer cell differentiation (GO:0032823)4.16089100
64citrulline biosynthetic process (GO:0019240)4.12012316
65negative regulation of phagocytosis (GO:0050765)4.10187200
66detection of external biotic stimulus (GO:0098581)4.10027906
67response to nitric oxide (GO:0071731)4.06969452
68erythrocyte development (GO:0048821)4.03729197
69myeloid cell development (GO:0061515)3.92735096
70dendritic cell migration (GO:0036336)3.88324740
71neutrophil mediated immunity (GO:0002446)3.88261951
72neutrophil activation involved in immune response (GO:0002283)3.84920628
73heme metabolic process (GO:0042168)3.79671342
74positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.77616977
75response to bacterium (GO:0009617)3.76500467
76regulation of mast cell degranulation (GO:0043304)3.75468009
77negative regulation of erythrocyte differentiation (GO:0045647)3.75422518
78biotin metabolic process (GO:0006768)3.75144318
79positive regulation of glycoprotein metabolic process (GO:1903020)3.72017818
80positive regulation of steroid hormone secretion (GO:2000833)3.71206965
81reactive oxygen species biosynthetic process (GO:1903409)3.70050500
82detection of biotic stimulus (GO:0009595)3.65328309
83macrophage differentiation (GO:0030225)3.65173342
84disruption of cells of other organism (GO:0044364)3.64795626
85killing of cells of other organism (GO:0031640)3.64795626
86regulation of leukocyte degranulation (GO:0043300)3.63216756
87negative regulation of interleukin-6 production (GO:0032715)3.61742206
88modification of morphology or physiology of other organism (GO:0035821)3.61063443
89regulation of myeloid leukocyte mediated immunity (GO:0002886)3.59931652
90regulation of mast cell activation involved in immune response (GO:0033006)3.54859222
91regulation of neutrophil migration (GO:1902622)3.54426841
92regulation of neutrophil chemotaxis (GO:0090022)3.54426841
93Arp2/3 complex-mediated actin nucleation (GO:0034314)3.52545446
94* leukotriene metabolic process (GO:0006691)3.46067097
95* neutrophil activation (GO:0042119)3.45293590
96positive regulation of interleukin-1 beta secretion (GO:0050718)3.45257559
97regulation of T-helper cell differentiation (GO:0045622)3.40110709
98regulation of response to osmotic stress (GO:0047484)3.33435676
99myeloid leukocyte migration (GO:0097529)3.29916176
100antigen processing and presentation of endogenous antigen (GO:0019883)3.25925637
101regulation of granulocyte chemotaxis (GO:0071622)3.23040452
102regulation of regulated secretory pathway (GO:1903305)3.21533740
103positive regulation of mast cell degranulation (GO:0043306)3.21370993
104positive regulation of mast cell activation involved in immune response (GO:0033008)3.21370993
105response to prostaglandin E (GO:0034695)3.20104925
106granulocyte migration (GO:0097530)3.18726754
107positive regulation of interleukin-1 secretion (GO:0050716)3.18688000
108positive regulation of interleukin-1 production (GO:0032732)3.18174662
109positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.13569423
110glucose catabolic process (GO:0006007)3.13435712
111megakaryocyte development (GO:0035855)3.10377931
112response to peptidoglycan (GO:0032494)3.09577208
113myeloid leukocyte mediated immunity (GO:0002444)3.08552926
114regulation of interleukin-1 beta secretion (GO:0050706)3.08262367
115regulation of T-helper 1 type immune response (GO:0002825)3.06495249
116B cell receptor signaling pathway (GO:0050853)3.06468159
117pentose metabolic process (GO:0019321)3.06373561
118activated T cell proliferation (GO:0050798)3.06017322
119positive regulation of B cell differentiation (GO:0045579)3.04269380
120* granulocyte activation (GO:0036230)3.02842119
121positive regulation of granulocyte differentiation (GO:0030854)3.00707851
122negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.99143248
123cellular extravasation (GO:0045123)2.97223594
124negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)2.95916525
125* leukotriene biosynthetic process (GO:0019370)2.94445635
126leukocyte mediated cytotoxicity (GO:0001909)2.94341481
127antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.89981684
128negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.88212894
129production of molecular mediator involved in inflammatory response (GO:0002532)2.87923526
130positive regulation of mast cell activation (GO:0033005)2.85320986
131hormone catabolic process (GO:0042447)2.83662551
132regulation of mast cell activation (GO:0033003)2.82842176
133regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.82212964
134antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.81721235
135antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.81721235
136positive regulation of NF-kappaB import into nucleus (GO:0042346)2.81052174
137positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.80066850
138mechanosensory behavior (GO:0007638)2.79991557
139positive regulation of gamma-delta T cell activation (GO:0046645)2.79401681
140mannose metabolic process (GO:0006013)2.78653141
141actin nucleation (GO:0045010)2.77437875
142phagosome maturation (GO:0090382)2.77404677
143negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.76980567
144negative regulation of cell killing (GO:0031342)2.76980567
145detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.76640857
146detection of temperature stimulus involved in sensory perception (GO:0050961)2.76640857
147definitive hemopoiesis (GO:0060216)2.76222277
148positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.75671404
149defense response to other organism (GO:0098542)2.75418923
150mast cell activation (GO:0045576)2.75237941
151humoral immune response (GO:0006959)2.74890969
152neutrophil chemotaxis (GO:0030593)2.73892679
153cellular response to hydrogen peroxide (GO:0070301)2.72674754
154cytokine secretion (GO:0050663)2.71590721
155DNA unwinding involved in DNA replication (GO:0006268)2.71174580
156regulation of tolerance induction (GO:0002643)2.70423968
157bicarbonate transport (GO:0015701)2.68041121
158regulation of receptor biosynthetic process (GO:0010869)2.67959933
159tetrapyrrole metabolic process (GO:0033013)2.67726463
160cellular response to interleukin-6 (GO:0071354)2.67505862
161neutrophil migration (GO:1990266)2.67101888
162positive regulation of phosphatidylinositol 3-kinase activity (GO:0043552)2.66765769
1633-UTR-mediated mRNA stabilization (GO:0070935)2.65738997
164regulation of interleukin-1 secretion (GO:0050704)2.65035821
165pinocytosis (GO:0006907)2.62710024
166negative regulation of interleukin-10 production (GO:0032693)12.1795034
167antibacterial humoral response (GO:0019731)12.0321322
168innate immune response in mucosa (GO:0002227)11.6614846
169antimicrobial humoral response (GO:0019730)11.0752252

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.65164859
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.47295455
3* MYB_21317192_ChIP-Seq_ERMYB_Mouse4.46727896
4VDR_21846776_ChIP-Seq_THP-1_Human3.69645266
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.66539990
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.48573740
7GATA1_22025678_ChIP-Seq_K562_Human3.25208346
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.00691513
9IRF8_27001747_Chip-Seq_BMDM_Mouse2.96736646
10BRD4_27068464_Chip-Seq_AML-cells_Mouse2.96267542
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.95600731
12SCL_19346495_ChIP-Seq_HPC-7_Human2.84138951
13NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.79578489
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.71925628
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.66302540
16MYC_22102868_ChIP-Seq_BL_Human2.65358630
17VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.57516331
18VDR_24763502_ChIP-Seq_THP-1_Human2.50320478
19SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.48104539
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.36989668
21IRF8_22096565_ChIP-ChIP_GC-B_Human2.33590361
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.30035525
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.28864782
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.27496148
25MYB_26560356_Chip-Seq_TH2_Human2.16738840
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.16710357
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.14132913
28STAT4_19710469_ChIP-ChIP_TH1__Mouse2.09465739
29BP1_19119308_ChIP-ChIP_Hs578T_Human2.05202947
30FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.97086021
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.94552563
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.94157960
33MAF_26560356_Chip-Seq_TH1_Human1.92705541
34UTX_26944678_Chip-Seq_JUKART_Human1.88876712
35* SPI1_23547873_ChIP-Seq_NB4_Human1.85543377
36AR_21909140_ChIP-Seq_LNCAP_Human1.80932096
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75086711
38E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.73973329
39TCF7_22412390_ChIP-Seq_EML_Mouse1.73751900
40KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.72303464
41GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.71843640
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.69066293
43LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.68522059
44ESR1_15608294_ChIP-ChIP_MCF-7_Human1.62672225
45NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.62623162
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.62065943
47RUNX_20019798_ChIP-Seq_JUKART_Human1.61015206
48FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.60571627
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.59594698
50TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.58345697
51RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.56630697
52SPI1_23127762_ChIP-Seq_K562_Human1.54613882
53STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.53155597
54* LXR_22292898_ChIP-Seq_THP-1_Human1.50423201
55NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.50211348
56MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.46371286
57ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.44188667
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.42811002
59BCOR_27268052_Chip-Seq_Bcells_Human1.42324901
60MYB_26560356_Chip-Seq_TH1_Human1.40867173
61EGR1_19032775_ChIP-ChIP_M12_Human1.39927835
62E2F1_21310950_ChIP-Seq_MCF-7_Human1.39838764
63PU_27001747_Chip-Seq_BMDM_Mouse1.39659349
64NCOR1_26117541_ChIP-Seq_K562_Human1.38833310
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.38603991
66MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.37730310
67MYC_18940864_ChIP-ChIP_HL60_Human1.36770619
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.36146857
69GATA3_27048872_Chip-Seq_THYMUS_Human1.35160144
70ELF1_20517297_ChIP-Seq_JURKAT_Human1.34866695
71VDR_22108803_ChIP-Seq_LS180_Human1.34342438
72FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.31968376
73* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.31456745
74FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.27405796
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.26609444
76GATA1_19941827_ChIP-Seq_MEL_Mouse1.23364964
77FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.21790381
78GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21179233
79BCL6_27268052_Chip-Seq_Bcells_Human1.20239181
80VDR_24787735_ChIP-Seq_THP-1_Human1.16598919
81GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.15638664
82P68_20966046_ChIP-Seq_HELA_Human1.14213118
83CTCF_27219007_Chip-Seq_ERYTHROID_Human1.11598687
84KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10825549
85GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10630805
86CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08647191
87ELK3_25401928_ChIP-Seq_HUVEC_Human1.07056641
88KDM2B_26808549_Chip-Seq_DND41_Human1.05177044
89PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03519663
90PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02944295
91MAF_26560356_Chip-Seq_TH2_Human1.02249547
92RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01628192
93ELF1_17652178_ChIP-ChIP_JURKAT_Human1.01018709
94IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00978429
95Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.00611015
96KDM2B_26808549_Chip-Seq_SUP-B15_Human0.99732100
97KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.98959242
98SPI1_20517297_ChIP-Seq_HL60_Human0.97218049
99* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96969480
100GATA3_26560356_Chip-Seq_TH2_Human0.96612019
101GATA2_19941826_ChIP-Seq_K562_Human0.95695076
102SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95592599
103SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95469852
104ETV2_25802403_ChIP-Seq_MESCs_Mouse0.93675766
105CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92256209
106CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90572435
107GATA1_19941827_ChIP-Seq_MEL86_Mouse0.89300472
108PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87481204
109CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86907240
110SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86233319
111IGF1R_20145208_ChIP-Seq_DFB_Human0.84257765
112CIITA_25753668_ChIP-Seq_RAJI_Human0.83723787
113KDM2B_26808549_Chip-Seq_JURKAT_Human0.82739035
114CTCF_21964334_ChIP-Seq_BJAB-B_Human0.80993468
115TP53_16413492_ChIP-PET_HCT116_Human0.80067123
116SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78694747
117GATA1_19941826_ChIP-Seq_K562_Human0.78635455
118GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77279247
119TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.76735898
120TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.76317708
121STAT1_17558387_ChIP-Seq_HELA_Human0.76245115
122* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.74117259
123TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.74092402
124FOXO3_23340844_ChIP-Seq_DLD1_Human0.73883156
125CLOCK_20551151_ChIP-Seq_293T_Human0.73251488

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002877_abnormal_melanocyte_morpholog5.78522192
2MP0005645_abnormal_hypothalamus_physiol4.65321280
3MP0000685_abnormal_immune_system4.31892619
4MP0002876_abnormal_thyroid_physiology4.05922197
5MP0003303_peritoneal_inflammation3.85773426
6MP0001835_abnormal_antigen_presentation3.62606989
7MP0002735_abnormal_chemical_nociception3.39356737
8MP0003436_decreased_susceptibility_to2.91699564
9MP0004510_myositis2.86741861
10MP0005671_abnormal_response_to2.77246130
11MP0005058_abnormal_lysosome_morphology2.65114721
12MP0005083_abnormal_biliary_tract2.60558048
13MP0003183_abnormal_peptide_metabolism2.47437333
14MP0005025_abnormal_response_to2.33172812
15MP0002419_abnormal_innate_immunity2.27718365
16MP0009278_abnormal_bone_marrow2.22421310
17MP0005464_abnormal_platelet_physiology2.14953694
18MP0001800_abnormal_humoral_immune2.11560871
19MP0009785_altered_susceptibility_to2.10488919
20MP0001764_abnormal_homeostasis2.00649886
21MP0002405_respiratory_system_inflammati1.94822893
22MP0005000_abnormal_immune_tolerance1.93422560
23MP0005310_abnormal_salivary_gland1.87554593
24MP0003172_abnormal_lysosome_physiology1.84733835
25MP0001853_heart_inflammation1.83934879
26MP0002398_abnormal_bone_marrow1.80799815
27MP0002420_abnormal_adaptive_immunity1.80657888
28MP0002396_abnormal_hematopoietic_system1.79724434
29MP0001819_abnormal_immune_cell1.78078918
30MP0002452_abnormal_antigen_presenting1.77719192
31MP0000465_gastrointestinal_hemorrhage1.76094578
32MP0005387_immune_system_phenotype1.74641440
33MP0001790_abnormal_immune_system1.74641440
34MP0009764_decreased_sensitivity_to1.72760619
35MP0002638_abnormal_pupillary_reflex1.70529406
36MP0003300_gastrointestinal_ulcer1.70491641
37MP0000716_abnormal_immune_system1.70236068
38MP0001545_abnormal_hematopoietic_system1.68166488
39MP0005397_hematopoietic_system_phenotyp1.68166488
40MP0008260_abnormal_autophagy1.65800444
41MP0001348_abnormal_lacrimal_gland1.64068210
42MP0000003_abnormal_adipose_tissue1.62520911
43MP0003045_fibrosis1.60772365
44MP0003656_abnormal_erythrocyte_physiolo1.59744110
45MP0002723_abnormal_immune_serum1.58254604
46MP0002009_preneoplasia1.54876999
47MP0001845_abnormal_inflammatory_respons1.50249065
48MP0002429_abnormal_blood_cell1.49659074
49MP0001851_eye_inflammation1.44358511
50MP0002148_abnormal_hypersensitivity_rea1.38819995
51MP0001533_abnormal_skeleton_physiology1.38604228
52MP0002971_abnormal_brown_adipose1.37850676
53MP0009115_abnormal_fat_cell1.36696096
54MP0003828_pulmonary_edema1.35370133
55MP0004185_abnormal_adipocyte_glucose1.32385990
56MP0004808_abnormal_hematopoietic_stem1.31155305
57MP0000689_abnormal_spleen_morphology1.27241778
58MP0003879_abnormal_hair_cell1.25448501
59MP0003959_abnormal_lean_body1.25349633
60MP0006054_spinal_hemorrhage1.24315187
61MP0002722_abnormal_immune_system1.23471883
62MP0010155_abnormal_intestine_physiology1.21936951
63MP0010307_abnormal_tumor_latency1.19325848
64MP0004134_abnormal_chest_morphology1.17928274
65MP0008874_decreased_physiological_sensi1.15840029
66MP0000343_altered_response_to1.15827304
67MP0009333_abnormal_splenocyte_physiolog1.15565975
68MP0003806_abnormal_nucleotide_metabolis1.13234876
69MP0003868_abnormal_feces_composition1.12981239
70MP0002254_reproductive_system_inflammat1.11078496
71MP0002970_abnormal_white_adipose1.06445510
72MP0006082_CNS_inflammation1.04021322
73MP0003638_abnormal_response/metabolism_1.03788691
74MP0005636_abnormal_mineral_homeostasis1.00680576
75MP0003111_abnormal_nucleus_morphology0.99049919
76MP0010352_gastrointestinal_tract_polyps0.99042942
77MP0001986_abnormal_taste_sensitivity0.98742737
78MP0005075_abnormal_melanosome_morpholog0.98484758
79MP0008469_abnormal_protein_level0.98384313
80MP0003221_abnormal_cardiomyocyte_apopto0.97211550
81MP0001873_stomach_inflammation0.95962564
82MP0009931_abnormal_skin_appearance0.93483429
83MP0009765_abnormal_xenobiotic_induced0.93243540
84MP0000703_abnormal_thymus_morphology0.92952249
85MP0004264_abnormal_extraembryonic_tissu0.91551949
86MP0003693_abnormal_embryo_hatching0.87764277
87MP0009763_increased_sensitivity_to0.87213740
88MP0003566_abnormal_cell_adhesion0.84497464
89MP0002733_abnormal_thermal_nociception0.83899485
90MP0002166_altered_tumor_susceptibility0.83179150
91MP0010094_abnormal_chromosome_stability0.81427602
92MP0005164_abnormal_response_to0.80003319
93MP0003724_increased_susceptibility_to0.79241353
94MP0000015_abnormal_ear_pigmentation0.78959357
95MP0000858_altered_metastatic_potential0.78925354
96MP0002132_abnormal_respiratory_system0.78150474
97MP0003075_altered_response_to0.77904820
98MP0003795_abnormal_bone_structure0.76457704
99MP0000609_abnormal_liver_physiology0.75773562
100MP0005666_abnormal_adipose_tissue0.75407133
101MP0000920_abnormal_myelination0.74223390
102MP0000681_abnormal_thyroid_gland0.73928145
103MP0000249_abnormal_blood_vessel0.73369383
104MP0000371_diluted_coat_color0.72574946
105MP0002138_abnormal_hepatobiliary_system0.70195642
106MP0003866_abnormal_defecation0.69149973
107MP0003448_altered_tumor_morphology0.69097042
108MP0002998_abnormal_bone_remodeling0.68398087
109MP0001970_abnormal_pain_threshold0.66216428
110MP0008775_abnormal_heart_ventricle0.66183602
111MP0005390_skeleton_phenotype0.65466028
112MP0004147_increased_porphyrin_level0.65455636
113MP0002019_abnormal_tumor_incidence0.64767288
114MP0003763_abnormal_thymus_physiology0.64624865
115MP0008057_abnormal_DNA_replication0.63592735
116MP0004947_skin_inflammation0.63129632
117MP0004883_abnormal_blood_vessel0.62664128
118MP0001663_abnormal_digestive_system0.62566241
119MP0000490_abnormal_crypts_of0.61259332
120MP0003279_aneurysm0.59819696
121MP0005174_abnormal_tail_pigmentation0.59795680
122MP0003191_abnormal_cellular_cholesterol0.59025645
123MP0002006_tumorigenesis0.57620824
124MP0000604_amyloidosis0.55292669
125MP0005076_abnormal_cell_differentiation0.53224079
126MP0005621_abnormal_cell_physiology0.53131093
127MP0003690_abnormal_glial_cell0.52398480
128MP0000749_muscle_degeneration0.52046349
129MP0005409_darkened_coat_color0.50670837
130MP0005376_homeostasis/metabolism_phenot0.50491663
131MP0005319_abnormal_enzyme/_coenzyme0.49732590
132MP0000598_abnormal_liver_morphology0.49593503
133MP0002095_abnormal_skin_pigmentation0.48260995

Predicted human phenotypes

RankGene SetZ-score
1Hypochromic anemia (HP:0001931)6.39253061
2Papilledema (HP:0001085)6.29757014
3Microcytic anemia (HP:0001935)5.71824459
4Eczematoid dermatitis (HP:0000976)5.41766663
5Recurrent abscess formation (HP:0002722)5.38892955
6Polycythemia (HP:0001901)5.24468312
7Abnormal hemoglobin (HP:0011902)5.16276034
8Recurrent bacterial skin infections (HP:0005406)5.12765287
9Recurrent gram-negative bacterial infections (HP:0005420)5.00088315
10Cholelithiasis (HP:0001081)4.52722057
11Paralysis (HP:0003470)4.51892219
12Thrombocytosis (HP:0001894)4.51539225
13Cellulitis (HP:0100658)4.39917828
14Recurrent fungal infections (HP:0002841)4.37152098
15Prolonged neonatal jaundice (HP:0006579)4.27531300
16Toxemia of pregnancy (HP:0100603)4.27026380
17Recurrent skin infections (HP:0001581)4.15594625
18Increased IgE level (HP:0003212)4.12563437
19Reticulocytosis (HP:0001923)4.10278688
20Obstructive lung disease (HP:0006536)4.09793834
21Chronic obstructive pulmonary disease (HP:0006510)4.09793834
22Abnormal gallbladder morphology (HP:0012437)4.05885410
23Recurrent cutaneous fungal infections (HP:0011370)4.02907095
24Chronic mucocutaneous candidiasis (HP:0002728)4.02907095
25Annular pancreas (HP:0001734)4.00085952
26Increased neuronal autofluorescent lipopigment (HP:0002074)3.97674784
27Diaphragmatic weakness (HP:0009113)3.92594439
28Increased cerebral lipofuscin (HP:0011813)3.90318647
29Aplasia/Hypoplasia of the spleen (HP:0010451)3.87815157
30Poikilocytosis (HP:0004447)3.75812132
31Recurrent pneumonia (HP:0006532)3.59549822
32Abnormality of iron homeostasis (HP:0011031)3.56708316
33Petechiae (HP:0000967)3.54456159
34Abnormal delayed hypersensitivity skin test (HP:0002963)3.43029906
35Meningitis (HP:0001287)3.42365742
36Gastrointestinal stroma tumor (HP:0100723)3.41119260
37Abnormal platelet function (HP:0011869)3.32680486
38Impaired platelet aggregation (HP:0003540)3.32680486
39Recurrent viral infections (HP:0004429)3.26810154
40Verrucae (HP:0200043)3.24328329
41Papilloma (HP:0012740)3.24328329
42Recurrent lower respiratory tract infections (HP:0002783)3.16603685
43Mediastinal lymphadenopathy (HP:0100721)3.14227135
44Confusion (HP:0001289)3.12076185
45Abnormality of reticulocytes (HP:0004312)3.08060299
46Chest pain (HP:0100749)3.06786342
47Inflammation of the large intestine (HP:0002037)3.05558020
48Poikiloderma (HP:0001029)3.01171757
49Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.96711541
50Agammaglobulinemia (HP:0004432)2.94711866
51Gastrointestinal inflammation (HP:0004386)2.93753887
52Abnormality of the gallbladder (HP:0005264)2.93399401
53Abnormal gallbladder physiology (HP:0012438)2.90167883
54Cholecystitis (HP:0001082)2.90167883
55Colitis (HP:0002583)2.89599320
56Seborrheic dermatitis (HP:0001051)2.87359145
57Vasculitis (HP:0002633)2.86957024
58Abnormality of liposaccharide metabolism (HP:0010968)2.84395309
59Abnormality of glycosphingolipid metabolism (HP:0004343)2.84395309
60Abnormality of glycolipid metabolism (HP:0010969)2.84395309
61Hyperglycinuria (HP:0003108)2.83852748
62Stomatitis (HP:0010280)2.83694549
63Abnormality of macrophages (HP:0004311)2.77750545
64Urticaria (HP:0001025)2.73808793
65Ileus (HP:0002595)2.71898122
66Entropion (HP:0000621)2.68795010
67Acanthocytosis (HP:0001927)2.67980695
68Gingivitis (HP:0000230)2.65657385
69Abnormal platelet volume (HP:0011876)2.59468278
70Hyperthyroidism (HP:0000836)2.59278538
71Thyroid-stimulating hormone excess (HP:0002925)2.57839391
72Abnormality of T cell physiology (HP:0011840)2.55792202
73Osteomyelitis (HP:0002754)2.53485258
74Ketoacidosis (HP:0001993)2.52540226
75Lymphopenia (HP:0001888)2.51769297
76Abnormality of transition element cation homeostasis (HP:0011030)2.51500580
77Myositis (HP:0100614)2.50529598
78Gingival bleeding (HP:0000225)2.49932735
79Abnormal pancreas size (HP:0012094)2.49805937
80Abnormality of cells of the lymphoid lineage (HP:0012140)2.49290200
81Abnormality of the fingertips (HP:0001211)2.49175336
82Recurrent sinusitis (HP:0011108)2.48111134
83Nonimmune hydrops fetalis (HP:0001790)2.45036306
84Hepatosplenomegaly (HP:0001433)2.44980078
85Panhypogammaglobulinemia (HP:0003139)2.44325169
86Thyroiditis (HP:0100646)2.44219940
87Squamous cell carcinoma (HP:0002860)2.44151137
88IgG deficiency (HP:0004315)2.43503681
89Ankyloglossia (HP:0010296)2.42593096
90Autoimmune thrombocytopenia (HP:0001973)2.41566897
91Chronic otitis media (HP:0000389)2.41544423
92B lymphocytopenia (HP:0010976)2.39159044
93Abnormality of B cell number (HP:0010975)2.39159044
94IgM deficiency (HP:0002850)2.37951594
95Gastrointestinal infarctions (HP:0005244)2.37253059
96Periodontitis (HP:0000704)2.36722345
97Arterial thrombosis (HP:0004420)2.36374151
98Pallor (HP:0000980)2.36237048
99Elevated erythrocyte sedimentation rate (HP:0003565)2.35050803
100Abnormality of the aortic arch (HP:0012303)2.32615766
101Interstitial pulmonary disease (HP:0006530)2.31610985
102Sepsis (HP:0100806)2.27689903
103Bilateral microphthalmos (HP:0007633)2.27168893
104Amaurosis fugax (HP:0100576)2.27102049
105Spontaneous hematomas (HP:0007420)2.24094071
106Systemic lupus erythematosus (HP:0002725)2.21102647
107Increased serum ferritin (HP:0003281)2.18903974
108Restrictive lung disease (HP:0002091)2.18820981
109Epistaxis (HP:0000421)2.16186177
110Hyperbilirubinemia (HP:0002904)2.15208931
111Granulocytopenia (HP:0001913)2.14915841
112Dysostosis multiplex (HP:0000943)2.14353637
113Increased mean platelet volume (HP:0011877)2.13548091
114Encephalitis (HP:0002383)2.12651429
115Hypertensive crisis (HP:0100735)2.12413939
116Truncus arteriosus (HP:0001660)2.08619140
117Emphysema (HP:0002097)2.08094551
118Abnormality of serine family amino acid metabolism (HP:0010894)2.08062636
119Abnormality of glycine metabolism (HP:0010895)2.08062636
120Cerebral palsy (HP:0100021)2.07594702
121Abnormality of polysaccharide metabolism (HP:0011012)2.06129852
122Abnormality of glycosaminoglycan metabolism (HP:0004371)2.06129852
123Abnormality of mucopolysaccharide metabolism (HP:0011020)2.06129852
124Abnormality of oral frenula (HP:0000190)2.03053616
125Nausea (HP:0002018)2.01257968
126Paresthesia (HP:0003401)2.00498677
127Purpura (HP:0000979)2.00493899
128Abnormality of the heme biosynthetic pathway (HP:0010472)11.2865215
129Hypochromic microcytic anemia (HP:0004840)11.2745347
130Skin ulcer (HP:0200042)1.99327758
131Increased density of long bones (HP:0006392)1.99234258
132Pustule (HP:0200039)1.98650727
133Amelogenesis imperfecta (HP:0000705)1.97206849
134Eosinophilia (HP:0001880)1.92585809
135Vacuolated lymphocytes (HP:0001922)1.91083444
136Leukocytosis (HP:0001974)1.89778371
137Thrombophlebitis (HP:0004418)1.89658443
138Abnormality of T cells (HP:0002843)1.86632662
139Hypoproteinemia (HP:0003075)1.86207364
140Cutaneous photosensitivity (HP:0000992)1.83235633
141Prolonged bleeding time (HP:0003010)1.81847839
142Urinary glycosaminoglycan excretion (HP:0003541)1.79429879
143Mucopolysacchariduria (HP:0008155)1.79429879
144Abnormality of the gastric mucosa (HP:0004295)1.79308622
145Hypoparathyroidism (HP:0000829)1.78929018
146Skin rash (HP:0000988)1.78561738
147Insomnia (HP:0100785)1.78358154
148Episodic fever (HP:0001954)1.76544028
149Glomerulonephritis (HP:0000099)1.74492430
150Anorexia (HP:0002039)1.73353711
151Menorrhagia (HP:0000132)1.72642111
152Amyloidosis (HP:0011034)1.69352522
153Metaphyseal cupping (HP:0003021)1.68103732
154Diplopia (HP:0000651)1.67639099
155Abnormality of binocular vision (HP:0011514)1.67639099

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B3.95952836
2IRAK43.77630750
3ERN13.19082349
4BTK3.01669448
5GRK62.94331202
6TAOK12.87691809
7MAP3K142.81140895
8EEF2K2.43774848
9TAOK22.36961886
10ITK2.35948861
11RIPK42.33871529
12TEC2.31161384
13MAP3K62.27482241
14MAP3K112.15129797
15TESK12.15054738
16IRAK32.11697369
17MAP3K32.11213384
18EPHB12.01153436
19TESK22.01087193
20FES2.00172606
21MAP4K11.97028057
22CLK11.94372357
23EIF2AK11.91821525
24SYK1.90874487
25MAP3K101.89364812
26KDR1.88497609
27STK101.84361822
28PTK61.83083172
29MAP3K121.76817683
30PKN21.72903232
31ALK1.70709306
32PIK3CA1.67070226
33LRRK21.64453483
34KIT1.57697306
35MAP3K131.49540120
36TYK21.47728443
37TAOK31.44207753
38BLK1.42820396
39MAP2K31.37432375
40YES11.36955288
41HCK1.36027790
42PIK3CG1.34839404
43LIMK11.33975964
44TRIB31.32323460
45TBK11.26364286
46TRPM71.21048313
47CSK1.16519167
48MAPK41.13054143
49CDC71.11733963
50MARK31.01629777
51RPS6KB21.01388474
52LYN1.00949298
53PTK2B1.00724673
54NEK20.98703732
55PAK40.97575393
56MAP3K50.96214317
57HIPK20.95630233
58JAK20.94977203
59DAPK20.94120549
60BRSK10.93656389
61TTN0.92715053
62BMX0.91706737
63STK40.90973256
64ZAP700.90379464
65WEE10.89443021
66TNK20.86715659
67MAP3K10.86202613
68STK160.85204410
69MAP2K40.82952197
70PIM10.82751042
71RPS6KC10.82232546
72RPS6KL10.82232546
73CSF1R0.81942904
74IKBKB0.81218066
75MAPK120.80758941
76IKBKE0.80621524
77BMPR20.78963259
78MAP3K80.74819424
79PDPK10.74163900
80MATK0.70295385
81DYRK1B0.69626182
82PASK0.69503283
83BRSK20.69249155
84JAK10.68954156
85RPS6KA60.68421916
86SCYL20.67543943
87PDK10.67352242
88EIF2AK30.66103993
89LCK0.65865842
90TGFBR20.63325790
91PRKAA20.60898274
92JAK30.60451709
93PRKCD0.60326745
94CDC42BPA0.59304964
95EGFR0.59023815
96KSR20.58460645
97SIK20.57541359
98MAP2K10.56513166
99CDK40.56277653
100RPS6KA20.55783219
101WNK10.55512439
102MARK20.54997763
103PRKCQ0.53846888
104MAPK110.53681044
105RAF10.52869671
106MST40.52156841
107STK110.50264716
108CAMK1D0.49558770
109ERBB30.49518669
110ILK0.48681772
111RET0.47508176
112TXK0.46471882
113PDK20.45042416
114FLT30.44700125
115MAP2K20.44099772
116RPS6KA40.44067601
117FGFR30.43372634
118MAPK70.43075603
119ROCK20.42766636
120PRKG20.42128435
121ATR0.40025475
122CDK120.39470509
123FGR0.37780299
124CDK190.37344644
125MAP2K60.37340130
126PIM20.37218240
127SRC0.36320108
128MAP3K70.36138791
129DYRK30.35232822
130AURKB0.34212774
131MAPKAPK20.33987920
132MKNK10.33922994
133SIK30.33184332
134FYN0.33120353
135MYLK0.32933686
136EIF2AK20.32675990
137AKT30.32097966
138PRKACG0.31137852
139CSNK2A20.30816487
140CAMK1G0.30460748
141STK240.29931985
142BRD40.29069424
143DMPK0.29059237
144MAPK30.28421332
145CDK60.28104602
146MOS0.27454847
147FRK0.26597855
148AKT10.26264460
149SMG10.25256732

Predicted pathways (KEGG)

RankGene SetZ-score
1African trypanosomiasis_Homo sapiens_hsa051432.98530028
2Primary immunodeficiency_Homo sapiens_hsa053402.86610091
3Leishmaniasis_Homo sapiens_hsa051402.81518987
4Other glycan degradation_Homo sapiens_hsa005112.70680660
5Histidine metabolism_Homo sapiens_hsa003402.68729786
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.24557729
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.19936039
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.13949847
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.10655910
10B cell receptor signaling pathway_Homo sapiens_hsa046622.00912231
11Asthma_Homo sapiens_hsa0531010.3095402
12Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.96072463
13Pentose phosphate pathway_Homo sapiens_hsa000301.93733780
14DNA replication_Homo sapiens_hsa030301.83958988
15Osteoclast differentiation_Homo sapiens_hsa043801.81581958
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.79033259
17Antigen processing and presentation_Homo sapiens_hsa046121.61311655
18Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.41563425
19Tuberculosis_Homo sapiens_hsa051521.41141138
20Leukocyte transendothelial migration_Homo sapiens_hsa046701.41110748
21Chemokine signaling pathway_Homo sapiens_hsa040621.37971100
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27933289
23Legionellosis_Homo sapiens_hsa051341.23935719
24Hematopoietic cell lineage_Homo sapiens_hsa046401.18808467
25Phagosome_Homo sapiens_hsa041451.13999889
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10967791
27Renin-angiotensin system_Homo sapiens_hsa046141.09485912
28Pancreatic cancer_Homo sapiens_hsa052121.09318606
29Toll-like receptor signaling pathway_Homo sapiens_hsa046201.09281739
30Staphylococcus aureus infection_Homo sapiens_hsa051501.04329515
31Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.04185756
32Toxoplasmosis_Homo sapiens_hsa051451.03439207
33VEGF signaling pathway_Homo sapiens_hsa043701.01780880
34Non-homologous end-joining_Homo sapiens_hsa034501.01356217
35Platelet activation_Homo sapiens_hsa046111.00249028
36Pertussis_Homo sapiens_hsa051330.96072322
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.96023230
38Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.86718522
39Collecting duct acid secretion_Homo sapiens_hsa049660.85535073
40Shigellosis_Homo sapiens_hsa051310.82854490
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81811712
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81200777
43Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80774180
44p53 signaling pathway_Homo sapiens_hsa041150.77300810
45Melanoma_Homo sapiens_hsa052180.77227406
46Non-small cell lung cancer_Homo sapiens_hsa052230.75256485
47Hepatitis B_Homo sapiens_hsa051610.74240187
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73914108
49Chronic myeloid leukemia_Homo sapiens_hsa052200.73117978
50Viral carcinogenesis_Homo sapiens_hsa052030.73062629
51Apoptosis_Homo sapiens_hsa042100.72599083
52Renal cell carcinoma_Homo sapiens_hsa052110.71812159
53HIF-1 signaling pathway_Homo sapiens_hsa040660.70378331
54Galactose metabolism_Homo sapiens_hsa000520.70028234
55Malaria_Homo sapiens_hsa051440.68895088
56Type II diabetes mellitus_Homo sapiens_hsa049300.68263192
57Nitrogen metabolism_Homo sapiens_hsa009100.67768360
58Autoimmune thyroid disease_Homo sapiens_hsa053200.64832071
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.64367243
60Salmonella infection_Homo sapiens_hsa051320.64261807
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63667943
62Glycerophospholipid metabolism_Homo sapiens_hsa005640.63536161
63Fructose and mannose metabolism_Homo sapiens_hsa000510.62792796
64Systemic lupus erythematosus_Homo sapiens_hsa053220.62620844
65Acute myeloid leukemia_Homo sapiens_hsa052210.61582857
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.61232355
67Regulation of autophagy_Homo sapiens_hsa041400.59502941
68Cell cycle_Homo sapiens_hsa041100.58931994
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58468862
70Measles_Homo sapiens_hsa051620.58238477
71One carbon pool by folate_Homo sapiens_hsa006700.56953421
72RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56648413
73Amoebiasis_Homo sapiens_hsa051460.55207417
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54598352
75HTLV-I infection_Homo sapiens_hsa051660.54102712
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53352890
77ABC transporters_Homo sapiens_hsa020100.50284905
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.50225861
79FoxO signaling pathway_Homo sapiens_hsa040680.49440729
80Salivary secretion_Homo sapiens_hsa049700.49055908
81Hepatitis C_Homo sapiens_hsa051600.48984444
82Herpes simplex infection_Homo sapiens_hsa051680.48166763
83Allograft rejection_Homo sapiens_hsa053300.47984316
84Complement and coagulation cascades_Homo sapiens_hsa046100.47845494
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47061270
86Lysosome_Homo sapiens_hsa041420.46799168
87T cell receptor signaling pathway_Homo sapiens_hsa046600.46473735
88Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.45614190
89GnRH signaling pathway_Homo sapiens_hsa049120.44793464
90Carbon metabolism_Homo sapiens_hsa012000.43755603
91Rheumatoid arthritis_Homo sapiens_hsa053230.43580523
92Starch and sucrose metabolism_Homo sapiens_hsa005000.43232947
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42859323
94Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42857505
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42778866
96Bladder cancer_Homo sapiens_hsa052190.42634590
97Choline metabolism in cancer_Homo sapiens_hsa052310.42554303
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.41791843
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.40661793
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40382777
101Biosynthesis of amino acids_Homo sapiens_hsa012300.40356004
102MAPK signaling pathway_Homo sapiens_hsa040100.39473340
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38944200
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.38666250
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.38344796
106Graft-versus-host disease_Homo sapiens_hsa053320.37116906
107Phospholipase D signaling pathway_Homo sapiens_hsa040720.35803260
108Phenylalanine metabolism_Homo sapiens_hsa003600.34708790
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.34353443
110Small cell lung cancer_Homo sapiens_hsa052220.34074071
111Insulin resistance_Homo sapiens_hsa049310.33897377
112Arachidonic acid metabolism_Homo sapiens_hsa005900.32899492
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.32037031
114Glutathione metabolism_Homo sapiens_hsa004800.31876035
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31608464
116mTOR signaling pathway_Homo sapiens_hsa041500.30968477
117Insulin signaling pathway_Homo sapiens_hsa049100.30824633
118Prolactin signaling pathway_Homo sapiens_hsa049170.30247753
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30002138
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.28690273
121Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.28669462
122Influenza A_Homo sapiens_hsa051640.27546829
123Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26345772
124Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.26105147
125Thyroid hormone synthesis_Homo sapiens_hsa049180.25726406
126Glioma_Homo sapiens_hsa052140.25499171
127Base excision repair_Homo sapiens_hsa034100.25328282
128Viral myocarditis_Homo sapiens_hsa054160.24495780
129Glycosaminoglycan degradation_Homo sapiens_hsa005310.23563815
130TNF signaling pathway_Homo sapiens_hsa046680.23130188
131Proteoglycans in cancer_Homo sapiens_hsa052050.22632599
132Epstein-Barr virus infection_Homo sapiens_hsa051690.22110273
133N-Glycan biosynthesis_Homo sapiens_hsa005100.21925956
134Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.21793072
135Caffeine metabolism_Homo sapiens_hsa002320.20437482
136Alcoholism_Homo sapiens_hsa050340.18402954
137Rap1 signaling pathway_Homo sapiens_hsa040150.18360486
138Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18029666

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