PRIM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* DNA strand elongation involved in DNA replication (GO:0006271)5.90299150
2* DNA strand elongation (GO:0022616)5.63267649
3* telomere maintenance via semi-conservative replication (GO:0032201)5.61310722
4DNA unwinding involved in DNA replication (GO:0006268)5.41326309
5* DNA replication initiation (GO:0006270)5.29564588
6* telomere maintenance via recombination (GO:0000722)5.03027356
7* mitotic recombination (GO:0006312)4.92790387
8DNA replication checkpoint (GO:0000076)4.89946567
9CENP-A containing nucleosome assembly (GO:0034080)4.79580565
10chromatin remodeling at centromere (GO:0031055)4.72626118
11protein localization to kinetochore (GO:0034501)4.71236940
12nucleotide-excision repair, DNA gap filling (GO:0006297)4.51662581
13ribosomal small subunit assembly (GO:0000028)4.49884258
14kinetochore organization (GO:0051383)4.48212802
15* telomere maintenance via telomere lengthening (GO:0010833)4.47300641
16DNA replication-independent nucleosome organization (GO:0034724)4.35238489
17DNA replication-independent nucleosome assembly (GO:0006336)4.35238489
18DNA replication-dependent nucleosome assembly (GO:0006335)4.21760263
19DNA replication-dependent nucleosome organization (GO:0034723)4.21760263
20maturation of SSU-rRNA (GO:0030490)4.16073747
21mitotic metaphase plate congression (GO:0007080)4.16041175
22DNA ligation (GO:0006266)4.12124032
23regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.11004766
24nucleobase biosynthetic process (GO:0046112)4.10619036
25protein localization to chromosome, centromeric region (GO:0071459)4.09468624
26attachment of spindle microtubules to kinetochore (GO:0008608)4.09264943
27mitotic chromosome condensation (GO:0007076)4.08545021
28DNA double-strand break processing (GO:0000729)4.07481208
29histone exchange (GO:0043486)3.90534667
30kinetochore assembly (GO:0051382)3.87134362
31purine nucleobase biosynthetic process (GO:0009113)3.85662216
32metaphase plate congression (GO:0051310)3.85252128
33mitotic nuclear envelope disassembly (GO:0007077)3.83321440
34regulation of centriole replication (GO:0046599)3.81861207
35IMP biosynthetic process (GO:0006188)3.79801718
36meiotic chromosome segregation (GO:0045132)3.74323970
37nuclear pore organization (GO:0006999)3.72377214
38deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.70726395
39viral transcription (GO:0019083)3.69099279
40DNA deamination (GO:0045006)3.67796522
41formation of translation preinitiation complex (GO:0001731)3.67751645
42translational termination (GO:0006415)3.66578135
43mitotic sister chromatid segregation (GO:0000070)3.65446374
44DNA catabolic process, exonucleolytic (GO:0000738)3.61318680
45proteasome assembly (GO:0043248)3.61171921
46double-strand break repair via nonhomologous end joining (GO:0006303)3.60470139
47non-recombinational repair (GO:0000726)3.60470139
48replication fork processing (GO:0031297)3.58348710
49nuclear pore complex assembly (GO:0051292)3.57999259
50establishment of chromosome localization (GO:0051303)3.53423349
51nuclear envelope disassembly (GO:0051081)3.52247256
52membrane disassembly (GO:0030397)3.52247256
53resolution of meiotic recombination intermediates (GO:0000712)3.52184448
54folic acid-containing compound biosynthetic process (GO:0009396)3.52117868
55* telomere maintenance (GO:0000723)3.50566273
56ribosomal small subunit biogenesis (GO:0042274)3.50351311
57* telomere organization (GO:0032200)3.49740120
58establishment of viral latency (GO:0019043)3.48257102
59regulation of nuclear cell cycle DNA replication (GO:0033262)3.48196358
60sister chromatid segregation (GO:0000819)3.47456216
61regulation of double-strand break repair via homologous recombination (GO:0010569)3.44097915
62synapsis (GO:0007129)3.41281742
63protein K6-linked ubiquitination (GO:0085020)3.40433690
64regulation of DNA endoreduplication (GO:0032875)3.40289022
65negative regulation of DNA-dependent DNA replication (GO:2000104)3.39115110
66negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.39038025
67mitotic spindle checkpoint (GO:0071174)3.38839515
68ribosomal large subunit biogenesis (GO:0042273)3.37524589
69transcription-coupled nucleotide-excision repair (GO:0006283)3.37111995
70DNA geometric change (GO:0032392)3.35826620
71DNA duplex unwinding (GO:0032508)3.34956646
72translational elongation (GO:0006414)3.33451249
73IMP metabolic process (GO:0046040)3.32282114
74translesion synthesis (GO:0019985)3.31471482
75chromatin assembly or disassembly (GO:0006333)3.30815461
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.29793728
77anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.29586001
78mismatch repair (GO:0006298)3.26632307
79mitotic sister chromatid cohesion (GO:0007064)3.26291034
80ribonucleoprotein complex biogenesis (GO:0022613)3.25355104
81regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.23445374
82somatic hypermutation of immunoglobulin genes (GO:0016446)3.23299882
83somatic diversification of immune receptors via somatic mutation (GO:0002566)3.23299882
84deoxyribonucleotide biosynthetic process (GO:0009263)3.22387118
85translational initiation (GO:0006413)3.20942543
86maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.20422763
87regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.20220067
88regulation of mitotic spindle checkpoint (GO:1903504)3.20220067
89spindle checkpoint (GO:0031577)3.19159263
90establishment of integrated proviral latency (GO:0075713)3.17882002
91SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.17603977
92spliceosomal snRNP assembly (GO:0000387)3.17184259
93regulation of mitotic sister chromatid separation (GO:0010965)3.16862830
94regulation of mitotic sister chromatid segregation (GO:0033047)3.16862830
95regulation of sister chromatid segregation (GO:0033045)3.16862830
96regulation of spindle organization (GO:0090224)3.16531602
97postreplication repair (GO:0006301)3.15998250
98DNA synthesis involved in DNA repair (GO:0000731)3.15845673
99nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.15341408
100regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.14715982
101ribosome biogenesis (GO:0042254)3.14048570
102microtubule depolymerization (GO:0007019)3.11784960
103base-excision repair (GO:0006284)3.11713482
104* cell cycle G1/S phase transition (GO:0044843)3.09994388
105* G1/S transition of mitotic cell cycle (GO:0000082)3.09994388
106cotranslational protein targeting to membrane (GO:0006613)3.09819495
107negative regulation of mitotic sister chromatid separation (GO:2000816)3.09812565
108negative regulation of mitotic sister chromatid segregation (GO:0033048)3.09812565
109negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.09812565
110negative regulation of sister chromatid segregation (GO:0033046)3.09812565
111ATP-dependent chromatin remodeling (GO:0043044)3.09715153
112spindle assembly checkpoint (GO:0071173)3.09086252
113rRNA processing (GO:0006364)3.09069149
114DNA topological change (GO:0006265)3.08975171
115negative regulation of chromosome segregation (GO:0051985)3.08694882
116negative regulation of DNA recombination (GO:0045910)3.08675012
117regulation of helicase activity (GO:0051095)3.08048059
118mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.07556562
119protein targeting to ER (GO:0045047)3.07535103
120positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.07166267
121regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.07153911
122DNA replication (GO:0006260)3.06797647
123protein localization to chromosome (GO:0034502)3.04710022
124chromosome segregation (GO:0007059)3.03917266
125regulation of centrosome cycle (GO:0046605)3.03722205
126negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.03424193
127negative regulation of ligase activity (GO:0051352)3.03424193
128DNA conformation change (GO:0071103)3.02473953
129regulation of chromosome segregation (GO:0051983)3.01896918
130regulation of mitotic metaphase/anaphase transition (GO:0030071)3.00901799
131negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.00160013
132ribosome assembly (GO:0042255)3.00157285
133mitotic spindle assembly checkpoint (GO:0007094)2.99712357

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.51997718
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.38332189
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.18182343
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58020878
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.51243572
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.40460107
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.90857598
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.83245901
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.77166300
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.72084842
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71341746
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.57524148
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.55222309
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.53921734
15* AR_21909140_ChIP-Seq_LNCAP_Human2.39409049
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.36983720
17* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36189945
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33442785
19XRN2_22483619_ChIP-Seq_HELA_Human2.24710165
20VDR_23849224_ChIP-Seq_CD4+_Human2.22706475
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21285649
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.14639502
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.10432322
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04906773
25FOXP3_21729870_ChIP-Seq_TREG_Human2.00978595
26E2F7_22180533_ChIP-Seq_HELA_Human10.8798020
27DCP1A_22483619_ChIP-Seq_HELA_Human1.95916241
28* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94426231
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.94153571
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.84956146
31SALL1_21062744_ChIP-ChIP_HESCs_Human1.83939157
32NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.81910812
33* TTF2_22483619_ChIP-Seq_HELA_Human1.81324792
34* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81188783
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80445796
36EGR1_19374776_ChIP-ChIP_THP-1_Human1.79907311
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79412336
38* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.78367516
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78141703
40ELK1_19687146_ChIP-ChIP_HELA_Human1.76148203
41* GABP_19822575_ChIP-Seq_HepG2_Human1.74586337
42* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.69624536
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67179541
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59867034
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58914593
46YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58361419
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57993302
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55397978
49HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54599987
50CIITA_25753668_ChIP-Seq_RAJI_Human1.54576137
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48052180
52CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43164618
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40667707
54* SRF_21415370_ChIP-Seq_HL-1_Mouse1.37571953
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36693080
56KDM5A_27292631_Chip-Seq_BREAST_Human1.34079205
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.31379356
58MYC_22102868_ChIP-Seq_BL_Human1.31080336
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.30419582
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28010085
61E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27142026
62* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22396406
63TP63_19390658_ChIP-ChIP_HaCaT_Human1.22250603
64FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22110227
65ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21497539
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21429863
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21318899
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17028327
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.15238226
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12848659
71EWS_26573619_Chip-Seq_HEK293_Human1.07469003
72SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.05824550
73MYC_18940864_ChIP-ChIP_HL60_Human1.05723177
74NANOG_16153702_ChIP-ChIP_HESCs_Human1.04705972
75SOX2_16153702_ChIP-ChIP_HESCs_Human1.04065859
76CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02965852
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02086990
78PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.00990903
79KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00311921
80NOTCH1_21737748_ChIP-Seq_TLL_Human0.98634218
81TFEB_21752829_ChIP-Seq_HELA_Human0.97367593
82VDR_22108803_ChIP-Seq_LS180_Human0.96127662
83FUS_26573619_Chip-Seq_HEK293_Human0.95746698
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95566500
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95231265
86STAT3_1855785_ChIP-Seq_MESCs_Mouse0.95020529
87SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.94734425
88POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94296422
89DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91558767
90SPI1_23547873_ChIP-Seq_NB4_Human0.90073985
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89563504
92CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89108226
93VDR_21846776_ChIP-Seq_THP-1_Human0.87318105
94IGF1R_20145208_ChIP-Seq_DFB_Human0.84119264
95BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82524579
96POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.81587807
97ZNF274_21170338_ChIP-Seq_K562_Hela0.77601747
98SOX17_20123909_ChIP-Seq_XEN_Mouse0.77005794
99* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.75210879
100ELK1_22589737_ChIP-Seq_MCF10A_Human0.74137437
101CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73830519
102HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.72450564
103SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70995942
104FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.70513120
105NANOG_21062744_ChIP-ChIP_HESCs_Human0.69625345
106HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.69527735
107IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.69341586
108PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.68231257
109ESR1_15608294_ChIP-ChIP_MCF-7_Human0.67878163
110KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.66250307
111IRF1_19129219_ChIP-ChIP_H3396_Human0.64051702
112FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63858986
113POU3F2_20337985_ChIP-ChIP_501MEL_Human0.59387341
114TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.58691382

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.40478619
2MP0003693_abnormal_embryo_hatching5.34994256
3MP0008057_abnormal_DNA_replication4.66924383
4MP0003111_abnormal_nucleus_morphology4.65006670
5MP0004957_abnormal_blastocyst_morpholog4.39527179
6MP0003077_abnormal_cell_cycle4.16726860
7MP0008058_abnormal_DNA_repair3.61670166
8MP0008007_abnormal_cellular_replicative2.94449764
9MP0008932_abnormal_embryonic_tissue2.77920412
10MP0002396_abnormal_hematopoietic_system2.76924780
11MP0008877_abnormal_DNA_methylation2.47504752
12MP0003123_paternal_imprinting2.32420013
13MP0000350_abnormal_cell_proliferation2.17818314
14MP0001730_embryonic_growth_arrest2.15269285
15MP0003786_premature_aging1.99440833
16MP0010307_abnormal_tumor_latency1.86353389
17MP0000490_abnormal_crypts_of1.85255515
18MP0010352_gastrointestinal_tract_polyps1.83650795
19MP0006035_abnormal_mitochondrial_morpho1.80026674
20MP0004808_abnormal_hematopoietic_stem1.73631983
21MP0001529_abnormal_vocalization1.73050953
22MP0001697_abnormal_embryo_size1.60820641
23MP0003121_genomic_imprinting1.56286128
24MP0001672_abnormal_embryogenesis/_devel1.55294614
25MP0005380_embryogenesis_phenotype1.55294614
26MP0006054_spinal_hemorrhage1.52498796
27MP0002019_abnormal_tumor_incidence1.50932345
28MP0008995_early_reproductive_senescence1.48607357
29MP0000313_abnormal_cell_death1.48135390
30MP0002080_prenatal_lethality1.46309652
31MP0000372_irregular_coat_pigmentation1.41753025
32MP0005397_hematopoietic_system_phenotyp1.37827998
33MP0001545_abnormal_hematopoietic_system1.37827998
34MP0003984_embryonic_growth_retardation1.36823973
35MP0003763_abnormal_thymus_physiology1.36821196
36MP0002085_abnormal_embryonic_tissue1.36210742
37MP0002088_abnormal_embryonic_growth/wei1.32672911
38MP0001188_hyperpigmentation1.32573466
39MP0003567_abnormal_fetal_cardiomyocyte1.32518544
40MP0002210_abnormal_sex_determination1.27596076
41MP0009333_abnormal_splenocyte_physiolog1.25670287
42MP0006292_abnormal_olfactory_placode1.25049416
43MP0003718_maternal_effect1.24145834
44MP0002084_abnormal_developmental_patter1.20642917
45MP0002086_abnormal_extraembryonic_tissu1.20350296
46MP0004197_abnormal_fetal_growth/weight/1.20166903
47MP0000703_abnormal_thymus_morphology1.18819999
48MP0002398_abnormal_bone_marrow1.16699817
49MP0003315_abnormal_perineum_morphology1.15281964
50MP0004858_abnormal_nervous_system1.14614621
51MP0001293_anophthalmia1.14589206
52MP0001145_abnormal_male_reproductive1.10657565
53MP0009379_abnormal_foot_pigmentation1.10575576
54MP0003890_abnormal_embryonic-extraembry1.08147468
55MP0004147_increased_porphyrin_level1.06386390
56MP0002722_abnormal_immune_system1.03561448
57MP0003698_abnormal_male_reproductive1.00220153
58MP0000689_abnormal_spleen_morphology0.98495447
59MP0010030_abnormal_orbit_morphology0.97809083
60MP0002095_abnormal_skin_pigmentation0.97144533
61MP0001929_abnormal_gametogenesis0.96870010
62MP0000653_abnormal_sex_gland0.94844197
63MP0003122_maternal_imprinting0.93711236
64MP0003806_abnormal_nucleotide_metabolis0.93100555
65MP0005075_abnormal_melanosome_morpholog0.91144914
66MP0009697_abnormal_copulation0.91022592
67MP0006072_abnormal_retinal_apoptosis0.90762199
68MP0002429_abnormal_blood_cell0.88865678
69MP0001119_abnormal_female_reproductive0.88827735
70MP0000537_abnormal_urethra_morphology0.88415293
71MP0005394_taste/olfaction_phenotype0.88287987
72MP0005499_abnormal_olfactory_system0.88287987
73MP0004142_abnormal_muscle_tone0.86310624
74MP0002938_white_spotting0.86091947
75MP0002160_abnormal_reproductive_system0.84476770
76MP0005076_abnormal_cell_differentiation0.84306086
77MP0002132_abnormal_respiratory_system0.83171991
78MP0005174_abnormal_tail_pigmentation0.83071888
79MP0006276_abnormal_autonomic_nervous0.80211969
80MP0000858_altered_metastatic_potential0.78780341
81MP0003186_abnormal_redox_activity0.76762431
82MP0002697_abnormal_eye_size0.75973594
83MP0003941_abnormal_skin_development0.75235277
84MP0001764_abnormal_homeostasis0.74928497
85MP0009053_abnormal_anal_canal0.74819332
86MP0005389_reproductive_system_phenotype0.74302690
87MP0001346_abnormal_lacrimal_gland0.73782324
88MP0000566_synostosis0.73646079
89MP0002102_abnormal_ear_morphology0.72879176
90MP0002006_tumorigenesis0.72448333
91MP0002234_abnormal_pharynx_morphology0.71829207
92MP0000716_abnormal_immune_system0.71657643
93MP0005384_cellular_phenotype0.71495286
94MP0002161_abnormal_fertility/fecundity0.71072454
95MP0002233_abnormal_nose_morphology0.70431976
96MP0009672_abnormal_birth_weight0.70421154
97MP0000358_abnormal_cell_content/0.69806309
98MP0002111_abnormal_tail_morphology0.68157702
99MP0000631_abnormal_neuroendocrine_gland0.67063344
100MP0001915_intracranial_hemorrhage0.67057830
101MP0006036_abnormal_mitochondrial_physio0.66567855
102MP0003861_abnormal_nervous_system0.65864599
103MP0000569_abnormal_digit_pigmentation0.64571657
104MP0000647_abnormal_sebaceous_gland0.63730330
105MP0002751_abnormal_autonomic_nervous0.63165986
106MP0003880_abnormal_central_pattern0.62856844
107MP0005621_abnormal_cell_physiology0.62417520
108MP0001853_heart_inflammation0.62271351
109MP0001286_abnormal_eye_development0.62108990
110MP0003699_abnormal_female_reproductive0.62017833
111MP0003937_abnormal_limbs/digits/tail_de0.61638767
112MP0002075_abnormal_coat/hair_pigmentati0.60920240
113MP0002009_preneoplasia0.60066482
114MP0002092_abnormal_eye_morphology0.59526255
115MP0002166_altered_tumor_susceptibility0.59189389
116MP0008770_decreased_survivor_rate0.59132980
117MP0000477_abnormal_intestine_morphology0.58249387
118MP0008789_abnormal_olfactory_epithelium0.58230626
119MP0003119_abnormal_digestive_system0.57336248
120MP0009278_abnormal_bone_marrow0.57199862
121MP0003656_abnormal_erythrocyte_physiolo0.56901689
122MP0004133_heterotaxia0.56620805
123MP0001800_abnormal_humoral_immune0.56033499
124MP0001919_abnormal_reproductive_system0.55172003
125MP0000015_abnormal_ear_pigmentation0.55010434
126MP0003943_abnormal_hepatobiliary_system0.54840737
127MP0009703_decreased_birth_body0.53834033
128MP0002736_abnormal_nociception_after0.51295922
129MP0005391_vision/eye_phenotype0.48789403
130MP0001324_abnormal_eye_pigmentation0.48351041
131MP0005084_abnormal_gallbladder_morpholo0.48049319
132MP0000049_abnormal_middle_ear0.47354860

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.63789609
2Reticulocytopenia (HP:0001896)4.82407750
3Chromsome breakage (HP:0040012)4.59261605
4Abnormality of cells of the erythroid lineage (HP:0012130)4.40077883
5Abnormal number of erythroid precursors (HP:0012131)4.36490069
6Chromosomal breakage induced by crosslinking agents (HP:0003221)4.27816602
7Abnormality of chromosome stability (HP:0003220)3.79030007
8Breast hypoplasia (HP:0003187)3.78748517
9Oral leukoplakia (HP:0002745)3.76801699
10Colon cancer (HP:0003003)3.68177981
11Abnormality of the preputium (HP:0100587)3.57979689
12Meckel diverticulum (HP:0002245)3.48794676
13Patellar aplasia (HP:0006443)3.42726522
14Aplastic anemia (HP:0001915)3.40180384
15Abnormality of the ileum (HP:0001549)3.34700123
16Aplasia/Hypoplasia of the uvula (HP:0010293)3.19663796
17Aplasia/Hypoplasia of the patella (HP:0006498)3.15693318
18Medulloblastoma (HP:0002885)3.15665606
19Selective tooth agenesis (HP:0001592)3.03640608
20Acute necrotizing encephalopathy (HP:0006965)2.96531821
21Duodenal stenosis (HP:0100867)2.95121912
22Small intestinal stenosis (HP:0012848)2.95121912
23Myelodysplasia (HP:0002863)2.93985865
24Pallor (HP:0000980)2.89916340
25Acute encephalopathy (HP:0006846)2.84296569
2611 pairs of ribs (HP:0000878)2.83587281
27Macrocytic anemia (HP:0001972)2.82096633
28Absent thumb (HP:0009777)2.79944471
29Rough bone trabeculation (HP:0100670)2.73398822
30Abnormal mitochondria in muscle tissue (HP:0008316)2.72655495
31Bone marrow hypocellularity (HP:0005528)2.69873959
32Agnosia (HP:0010524)2.65752197
33Impulsivity (HP:0100710)2.64211684
34Carpal bone hypoplasia (HP:0001498)2.63443849
35Ependymoma (HP:0002888)2.60148449
36Cortical dysplasia (HP:0002539)2.59640084
37Premature graying of hair (HP:0002216)2.58752280
38Increased hepatocellular lipid droplets (HP:0006565)2.57780249
39Increased CSF lactate (HP:0002490)2.55909730
40Absent radius (HP:0003974)2.53573912
41Ectopic kidney (HP:0000086)2.51671282
42Sloping forehead (HP:0000340)2.51561327
43Degeneration of anterior horn cells (HP:0002398)2.50719011
44Abnormality of the anterior horn cell (HP:0006802)2.50719011
45Abnormality of the heme biosynthetic pathway (HP:0010472)2.50343801
46Duplicated collecting system (HP:0000081)2.49661008
47Abnormal number of incisors (HP:0011064)2.48293666
48Increased nuchal translucency (HP:0010880)2.47619092
49Abnormal lung lobation (HP:0002101)2.47361719
50Microvesicular hepatic steatosis (HP:0001414)2.45037555
51Volvulus (HP:0002580)2.44619903
52Mitochondrial inheritance (HP:0001427)2.43467419
53Neoplasm of the pancreas (HP:0002894)2.39718835
54Rhabdomyosarcoma (HP:0002859)2.38430433
55Abnormality of the carotid arteries (HP:0005344)2.37847018
56Abnormality of the duodenum (HP:0002246)2.37524226
57Abnormality of the labia minora (HP:0012880)2.37468028
58Lipid accumulation in hepatocytes (HP:0006561)2.37452692
59Progressive macrocephaly (HP:0004481)2.36986073
60Microretrognathia (HP:0000308)2.36718182
61Aplasia involving forearm bones (HP:0009822)2.35719338
62Absent forearm bone (HP:0003953)2.35719338
63Triphalangeal thumb (HP:0001199)2.30783619
64Abnormality of the renal collecting system (HP:0004742)2.30407837
65Hepatocellular necrosis (HP:0001404)2.29738836
66Atresia of the external auditory canal (HP:0000413)2.28396685
67Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28244277
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27345075
69Abnormal protein N-linked glycosylation (HP:0012347)2.27345075
70Abnormal protein glycosylation (HP:0012346)2.27345075
71Abnormal glycosylation (HP:0012345)2.27345075
72Abnormal hair whorl (HP:0010721)2.26408723
73Horseshoe kidney (HP:0000085)2.24358675
74Tracheoesophageal fistula (HP:0002575)2.23657244
75Cellular immunodeficiency (HP:0005374)2.23590440
76Increased serum lactate (HP:0002151)2.23370034
77Lymphoma (HP:0002665)2.20265769
78Cerebral edema (HP:0002181)2.20169308
79Basal cell carcinoma (HP:0002671)2.17862300
80Nephroblastoma (Wilms tumor) (HP:0002667)2.16494796
81Aplasia/Hypoplasia of the sternum (HP:0006714)2.16159435
82Clubbing of toes (HP:0100760)2.15736970
83Hypoplasia of the capital femoral epiphysis (HP:0003090)2.12917502
84Pancytopenia (HP:0001876)2.12276590
85Cleft eyelid (HP:0000625)2.10259595
86Proximal placement of thumb (HP:0009623)2.10183828
87IgM deficiency (HP:0002850)2.08707211
88Supernumerary spleens (HP:0009799)2.07090798
89Failure to thrive in infancy (HP:0001531)2.05809903
90Slender long bone (HP:0003100)2.03178581
91Hepatic necrosis (HP:0002605)2.02172842
92Embryonal renal neoplasm (HP:0011794)2.01691210
93Abnormality of DNA repair (HP:0003254)2.00589444
94Short thumb (HP:0009778)1.99968386
95Squamous cell carcinoma (HP:0002860)1.98681995
96Deviation of the thumb (HP:0009603)1.98626924
97Thrombocytosis (HP:0001894)1.97418635
98Type I transferrin isoform profile (HP:0003642)1.96781011
99Neoplasm of the colon (HP:0100273)1.96400331
100Cafe-au-lait spot (HP:0000957)1.95239192
101Abnormal trabecular bone morphology (HP:0100671)1.93089699
102Abnormality of reticulocytes (HP:0004312)1.92268052
103Multiple enchondromatosis (HP:0005701)1.91900962
104Abnormality of cochlea (HP:0000375)1.91260746
105Abnormality of the astrocytes (HP:0100707)1.89089847
106Astrocytoma (HP:0009592)1.89089847
107Cerebral hypomyelination (HP:0006808)1.88884869
108High pitched voice (HP:0001620)1.85591366
109Hyperglycinemia (HP:0002154)1.83521040
110Amaurosis fugax (HP:0100576)1.83363639
111Arteriovenous malformation (HP:0100026)1.83312491
112Acute lymphatic leukemia (HP:0006721)1.82230217
113Facial hemangioma (HP:0000329)1.81828681
114Lactic acidosis (HP:0003128)1.80598178
115Prominent nose (HP:0000448)1.80190798
116Optic nerve coloboma (HP:0000588)1.79485851
117Abnormality of pyrimidine metabolism (HP:0004353)1.78852045
118Asplenia (HP:0001746)1.77966948
119Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.77809668
120Increased serum pyruvate (HP:0003542)1.77710901
121Pancreatic fibrosis (HP:0100732)1.75820231
122Abnormal spermatogenesis (HP:0008669)1.75270899
123Astigmatism (HP:0000483)1.75129289
124Congenital primary aphakia (HP:0007707)1.73478136
125Abnormality of methionine metabolism (HP:0010901)1.72996397
126Choanal atresia (HP:0000453)1.72806716
127Missing ribs (HP:0000921)1.72752209
128Glioma (HP:0009733)1.70482444
129Abnormality of serum amino acid levels (HP:0003112)1.70026418
130Trismus (HP:0000211)1.69402008
131Poikiloderma (HP:0001029)1.69122347
132Biliary tract neoplasm (HP:0100574)1.68975500
133Medial flaring of the eyebrow (HP:0010747)1.68521037
134Hypoplasia of the pons (HP:0012110)1.67376543
135Poor coordination (HP:0002370)1.67045614
136True hermaphroditism (HP:0010459)1.66893639
137Abnormality of glycolysis (HP:0004366)1.66805579
138Short 4th metacarpal (HP:0010044)1.66611985
139Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.66611985
140Gait imbalance (HP:0002141)1.66517407
141Aplasia/Hypoplasia of the thymus (HP:0010515)1.66219429
142Pancreatic cysts (HP:0001737)1.65767633
143Abnormality of alanine metabolism (HP:0010916)1.65379574
144Hyperalaninemia (HP:0003348)1.65379574
145Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.65379574
146Leukodystrophy (HP:0002415)1.64286941

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.02749681
2WEE14.61790005
3BUB13.98243635
4VRK23.11170341
5EIF2AK13.06578091
6NEK22.94095122
7ACVR1B2.88782407
8SRPK12.73556004
9STK162.58789255
10BRSK22.58014159
11VRK12.46325584
12NME22.38184419
13NEK12.37260186
14TTK2.36931469
15PLK42.23769858
16CCNB12.16993720
17PLK12.12436917
18ATR2.04079836
19EIF2AK31.93379225
20MKNK11.91802838
21AURKB1.88255415
22PASK1.85548548
23TRIM281.83340527
24CDK71.78562948
25BRSK11.65931905
26NUAK11.65237473
27TLK11.63113601
28TSSK61.62902102
29TAF11.62888491
30DYRK31.56662232
31PLK31.56003081
32CHEK21.50393294
33ZAK1.39933229
34RPS6KA41.39667829
35RPS6KB21.33472846
36TESK21.32917944
37CDK41.26180066
38SCYL21.24222896
39STK41.23711816
40TGFBR11.23189758
41CHEK11.21300475
42MKNK21.20763361
43AURKA1.20685862
44CDK81.14855785
45MAP3K81.11450929
46BMPR1B1.10672575
47WNK31.09513418
48ATM1.02220942
49STK100.96002339
50PNCK0.93170346
51EIF2AK20.92190035
52CLK10.89076339
53BCR0.87536908
54MAP4K20.85880385
55CDK120.85405267
56CDK20.83122505
57MAP4K10.80791553
58DYRK20.78935163
59CDK190.78399345
60BRD40.77533576
61PIM10.77256210
62PAK40.75607812
63CSNK2A10.71602971
64PIM20.71062358
65CDK60.70767091
66MELK0.69691484
67CSNK2A20.68858283
68TNIK0.68668648
69CDK10.68450143
70EEF2K0.67451326
71FLT30.66055258
72TEC0.65597374
73PBK0.63548364
74MAPK130.60856418
75MST40.57085103
76BTK0.56907069
77PLK20.56547005
78LRRK20.55546796
79RPS6KA50.55067479
80KDR0.48275583
81PDK20.47721758
82TESK10.47668066
83MAP3K100.47114406
84MAPKAPK50.44588731
85CSNK1G10.43393580
86BCKDK0.42149554
87KIT0.41318222
88YES10.40918073
89PRKDC0.40802982
90PAK10.40188521
91CDK30.39104174
92MAP3K40.38543240
93STK30.38509803
94CDK180.36098254
95CDK11A0.34870507
96PRKCI0.34829805
97MAP2K30.34143271
98IRAK40.33093715
99ERBB30.32654053
100CDK150.32146856
101CDK140.31696258
102BRAF0.30806803
103EPHA20.30747703
104ALK0.30630239
105MINK10.30115692
106CSNK1G20.29025896
107FGFR10.28409081
108LYN0.28243809
109RAF10.26235501
110CSF1R0.24626857
111MAP2K70.24341333
112CSNK1A1L0.23826244
113AKT20.23636398
114TXK0.23011788
115PRKACB0.22273020
116PRKCG0.21434015
117AKT10.21432394
118MAPK140.21314664
119ERBB40.20195151
120NEK90.19706508
121CSNK1E0.19613259
122PKN20.19108263
123CDK90.19100803
124RPS6KC10.18684959
125RPS6KL10.18684959
126CSNK1D0.18565805
127ZAP700.18310709
128NME10.17881280
129BLK0.16471258
130TAOK20.16351390
131DAPK10.16162968
132RPS6KB10.16027410
133CSNK1G30.15959052

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030305.91556627
2Mismatch repair_Homo sapiens_hsa034304.98783902
3Homologous recombination_Homo sapiens_hsa034403.66582014
4Ribosome_Homo sapiens_hsa030103.43681501
5Base excision repair_Homo sapiens_hsa034103.41570293
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.20939586
7Nucleotide excision repair_Homo sapiens_hsa034203.20475926
8Spliceosome_Homo sapiens_hsa030403.19674556
9Cell cycle_Homo sapiens_hsa041102.95628644
10RNA polymerase_Homo sapiens_hsa030202.87484388
11Proteasome_Homo sapiens_hsa030502.82571352
12RNA transport_Homo sapiens_hsa030132.78407233
13One carbon pool by folate_Homo sapiens_hsa006702.68953828
14Fanconi anemia pathway_Homo sapiens_hsa034602.64352102
15* Pyrimidine metabolism_Homo sapiens_hsa002402.49126232
16Non-homologous end-joining_Homo sapiens_hsa034502.41157723
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.11616479
18RNA degradation_Homo sapiens_hsa030181.88198177
19Basal transcription factors_Homo sapiens_hsa030221.84532364
20p53 signaling pathway_Homo sapiens_hsa041151.63399644
21mRNA surveillance pathway_Homo sapiens_hsa030151.56597227
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46718192
23Propanoate metabolism_Homo sapiens_hsa006401.43550325
24Systemic lupus erythematosus_Homo sapiens_hsa053221.42847909
25Pyruvate metabolism_Homo sapiens_hsa006201.37244377
26* Purine metabolism_Homo sapiens_hsa002301.32360207
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22369905
28Steroid biosynthesis_Homo sapiens_hsa001001.16257181
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.07864364
30Protein export_Homo sapiens_hsa030601.06576679
31Fatty acid elongation_Homo sapiens_hsa000621.06296939
32Epstein-Barr virus infection_Homo sapiens_hsa051691.03945497
33Herpes simplex infection_Homo sapiens_hsa051680.95071580
34Viral carcinogenesis_Homo sapiens_hsa052030.92206651
35Oocyte meiosis_Homo sapiens_hsa041140.90339228
36Alzheimers disease_Homo sapiens_hsa050100.88916373
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82149986
38Antigen processing and presentation_Homo sapiens_hsa046120.80609695
39Folate biosynthesis_Homo sapiens_hsa007900.79695596
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76087703
41HTLV-I infection_Homo sapiens_hsa051660.73501978
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72399005
43Primary immunodeficiency_Homo sapiens_hsa053400.70405349
44Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.68108585
45Cyanoamino acid metabolism_Homo sapiens_hsa004600.65418201
46Pentose phosphate pathway_Homo sapiens_hsa000300.62943332
47Cysteine and methionine metabolism_Homo sapiens_hsa002700.62544885
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57215520
49Alcoholism_Homo sapiens_hsa050340.56987726
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56870205
51Small cell lung cancer_Homo sapiens_hsa052220.56780526
52Butanoate metabolism_Homo sapiens_hsa006500.56691466
53Drug metabolism - other enzymes_Homo sapiens_hsa009830.56676214
54Huntingtons disease_Homo sapiens_hsa050160.56361609
55Biosynthesis of amino acids_Homo sapiens_hsa012300.54283672
56MicroRNAs in cancer_Homo sapiens_hsa052060.54088035
57Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.52751161
58Fatty acid metabolism_Homo sapiens_hsa012120.51867847
59Selenocompound metabolism_Homo sapiens_hsa004500.50512850
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50433577
61Thyroid cancer_Homo sapiens_hsa052160.50096582
62N-Glycan biosynthesis_Homo sapiens_hsa005100.49877714
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47703019
64Glutathione metabolism_Homo sapiens_hsa004800.47544189
65Legionellosis_Homo sapiens_hsa051340.46991282
66Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.45652264
67Sulfur relay system_Homo sapiens_hsa041220.44499736
68Hematopoietic cell lineage_Homo sapiens_hsa046400.44446642
69Parkinsons disease_Homo sapiens_hsa050120.44059767
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40878803
71Peroxisome_Homo sapiens_hsa041460.40267435
72Hepatitis B_Homo sapiens_hsa051610.38455696
73Measles_Homo sapiens_hsa051620.37544491
74Apoptosis_Homo sapiens_hsa042100.37246362
75Cardiac muscle contraction_Homo sapiens_hsa042600.35770523
76Vitamin B6 metabolism_Homo sapiens_hsa007500.34391151
77Colorectal cancer_Homo sapiens_hsa052100.32537441
78Arginine and proline metabolism_Homo sapiens_hsa003300.30269850
79Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29925871
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.29684566
81TGF-beta signaling pathway_Homo sapiens_hsa043500.28286426
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.25958698
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24838543
84Basal cell carcinoma_Homo sapiens_hsa052170.23323527
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21157745
86Carbon metabolism_Homo sapiens_hsa012000.21145449
87Regulation of autophagy_Homo sapiens_hsa041400.20986944
88Shigellosis_Homo sapiens_hsa051310.19739316
89RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18586866
90* Metabolic pathways_Homo sapiens_hsa011000.17713196
91Pathways in cancer_Homo sapiens_hsa052000.17409804
92Influenza A_Homo sapiens_hsa051640.17103346
93Bladder cancer_Homo sapiens_hsa052190.16452361
94Chronic myeloid leukemia_Homo sapiens_hsa052200.16445986
95Viral myocarditis_Homo sapiens_hsa054160.15764123
96Phototransduction_Homo sapiens_hsa047440.15185884
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.14990128
98Hippo signaling pathway_Homo sapiens_hsa043900.13869510
99Allograft rejection_Homo sapiens_hsa053300.13264735
100Oxidative phosphorylation_Homo sapiens_hsa001900.13159089
101Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.12943042
102Galactose metabolism_Homo sapiens_hsa000520.12876344
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.12240915
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.12233231
105Prostate cancer_Homo sapiens_hsa052150.11939185
106Notch signaling pathway_Homo sapiens_hsa043300.11734002
107Asthma_Homo sapiens_hsa053100.11088843
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.10621782
109Nicotine addiction_Homo sapiens_hsa050330.09473739
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.08776259
111Lysine degradation_Homo sapiens_hsa003100.08136011
112Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.08115507
113Renin-angiotensin system_Homo sapiens_hsa046140.07915950
114Fatty acid degradation_Homo sapiens_hsa000710.07794780
115Non-small cell lung cancer_Homo sapiens_hsa052230.07466464
116Arachidonic acid metabolism_Homo sapiens_hsa005900.06700195
117Nitrogen metabolism_Homo sapiens_hsa009100.05961613
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.05843407
119beta-Alanine metabolism_Homo sapiens_hsa004100.05406994
120Fructose and mannose metabolism_Homo sapiens_hsa000510.05163929
121Pancreatic cancer_Homo sapiens_hsa052120.04937482
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.04743408
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.04528682
1242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.03467094
125Tryptophan metabolism_Homo sapiens_hsa003800.02998423
126Olfactory transduction_Homo sapiens_hsa047400.02192302
127Wnt signaling pathway_Homo sapiens_hsa043100.01424643
128Vitamin digestion and absorption_Homo sapiens_hsa049770.00146445
129Fatty acid biosynthesis_Homo sapiens_hsa00061-0.0132259
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.0036794

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