PRM3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.68413102
2plasma membrane fusion (GO:0045026)9.67453042
3reproduction (GO:0000003)9.29285843
4motile cilium assembly (GO:0044458)9.27268086
5axonemal dynein complex assembly (GO:0070286)9.24905989
6regulation of cilium movement (GO:0003352)8.06597937
7cilium movement (GO:0003341)7.71120303
8negative regulation of inclusion body assembly (GO:0090084)7.46513774
9cilium or flagellum-dependent cell motility (GO:0001539)7.42374492
10single fertilization (GO:0007338)7.18002017
11sperm capacitation (GO:0048240)7.16005677
12rRNA methylation (GO:0031167)7.15073546
13organic cation transport (GO:0015695)7.11997893
14* spermatogenesis (GO:0007283)6.94349783
15synaptonemal complex organization (GO:0070193)6.93887532
16* male gamete generation (GO:0048232)6.91942927
17synaptonemal complex assembly (GO:0007130)6.91842809
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.84293025
19microtubule depolymerization (GO:0007019)6.58939923
20male meiosis (GO:0007140)6.53950331
21protein targeting to Golgi (GO:0000042)6.49549874
22* gamete generation (GO:0007276)6.35469684
23phosphatidylethanolamine biosynthetic process (GO:0006646)6.31064242
24regulation of inclusion body assembly (GO:0090083)6.29040378
25establishment of protein localization to Golgi (GO:0072600)6.23568064
26antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.22750665
27fertilization (GO:0009566)6.16239682
28spermatid nucleus differentiation (GO:0007289)6.14863155
29cellular ketone body metabolic process (GO:0046950)6.08914556
30retrograde transport, vesicle recycling within Golgi (GO:0000301)6.03795202
31rRNA modification (GO:0000154)6.01152694
32piRNA metabolic process (GO:0034587)5.98677755
33calcium ion-dependent exocytosis (GO:0017156)5.92204891
34phosphatidylethanolamine metabolic process (GO:0046337)5.83580350
35germ cell development (GO:0007281)5.60109947
36sexual reproduction (GO:0019953)5.56780927
37cellular process involved in reproduction in multicellular organism (GO:0022412)5.51174324
38ketone body metabolic process (GO:1902224)5.37386968
39single strand break repair (GO:0000012)5.33104099
40glycerol ether metabolic process (GO:0006662)5.26995241
41cell recognition (GO:0008037)5.15937562
42regulation of Rab GTPase activity (GO:0032313)5.13480935
43positive regulation of Rab GTPase activity (GO:0032851)5.13480935
44centriole replication (GO:0007099)5.11750867
45* chromosome condensation (GO:0030261)5.06280731
46* multicellular organismal reproductive process (GO:0048609)4.97558797
47* DNA packaging (GO:0006323)4.97497921
48ether metabolic process (GO:0018904)4.86810081
49microtubule severing (GO:0051013)4.85113853
50seminiferous tubule development (GO:0072520)4.83783646
51ventricular system development (GO:0021591)4.82185888
52sequestering of actin monomers (GO:0042989)4.79256638
53chromosome organization involved in meiosis (GO:0070192)4.72173209
54regulation of microtubule-based movement (GO:0060632)4.67254916
55protein localization to Golgi apparatus (GO:0034067)4.66509645
56male meiosis I (GO:0007141)4.45525229
57regulation of transcription involved in cell fate commitment (GO:0060850)4.30758322
58regulation of centriole replication (GO:0046599)4.20965141
59coenzyme catabolic process (GO:0009109)4.18672477
60chaperone-mediated protein complex assembly (GO:0051131)4.05096090
61left/right pattern formation (GO:0060972)4.03344020
62DNA methylation involved in gamete generation (GO:0043046)4.02936940
63meiotic nuclear division (GO:0007126)3.98012472
64* multicellular organismal development (GO:0007275)3.97405811
65negative regulation of Rho protein signal transduction (GO:0035024)3.96873574
66protein K11-linked deubiquitination (GO:0035871)3.88019552
67meiosis I (GO:0007127)3.57893013
68positive regulation of macrophage activation (GO:0043032)3.54392502
69glomerular visceral epithelial cell development (GO:0072015)3.53660244
70protein polyglutamylation (GO:0018095)3.50902265
71cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.49894364
72musculoskeletal movement (GO:0050881)3.47156686
73multicellular organismal movement (GO:0050879)3.47156686
74genitalia morphogenesis (GO:0035112)3.46666097
75microtubule polymerization or depolymerization (GO:0031109)3.45899776
76polyamine biosynthetic process (GO:0006596)3.44214171
77interferon-gamma secretion (GO:0072643)3.44213034
78glomerular epithelial cell development (GO:0072310)3.41980764
79regulation of spindle checkpoint (GO:0090231)3.39602065
80peptidyl-threonine dephosphorylation (GO:0035970)3.36120888
81nucleus organization (GO:0006997)3.33415780
82regulation of interleukin-13 production (GO:0032656)3.33251213
83mesenchymal cell differentiation involved in kidney development (GO:0072161)3.31942145
84mesenchymal cell differentiation involved in renal system development (GO:2001012)3.31942145
85response to acidic pH (GO:0010447)3.31067266
86cerebral cortex neuron differentiation (GO:0021895)3.30994080
87protein refolding (GO:0042026)3.29974228
88regulation of T-helper 2 cell differentiation (GO:0045628)3.29137144
89histone H3-K9 demethylation (GO:0033169)3.27842532
90chromatin silencing (GO:0006342)3.24246670
91RNA localization (GO:0006403)3.22377715
92cell differentiation involved in metanephros development (GO:0072202)3.20005627
93RNA destabilization (GO:0050779)3.19514550
94monoubiquitinated protein deubiquitination (GO:0035520)3.13404567
95protein depolymerization (GO:0051261)3.12853620
96cellular response to pH (GO:0071467)3.12733420
97homeostasis of number of cells within a tissue (GO:0048873)3.12559502
98cranial nerve morphogenesis (GO:0021602)3.11364319
99glycolytic process (GO:0006096)3.10599462
100meiotic cell cycle (GO:0051321)3.04296900
101amino-acid betaine transport (GO:0015838)3.03657992
102carnitine transport (GO:0015879)3.03657992
103peptidyl-proline hydroxylation (GO:0019511)2.99599781
104NAD biosynthetic process (GO:0009435)2.98443800
105microtubule nucleation (GO:0007020)2.95238146
106nucleoside diphosphate phosphorylation (GO:0006165)2.90836194
107mitotic sister chromatid cohesion (GO:0007064)2.89592742
108negative regulation of histone methylation (GO:0031061)2.87713878
109synapsis (GO:0007129)2.86004067
110carnitine transmembrane transport (GO:1902603)2.84953419
111polyol catabolic process (GO:0046174)2.84099035
112receptor recycling (GO:0001881)2.82549634
113protein localization to cilium (GO:0061512)2.81002716
114protein-DNA complex disassembly (GO:0032986)2.80617558
115nucleosome disassembly (GO:0006337)2.80617558
116positive regulation of skeletal muscle tissue development (GO:0048643)2.77572769
117regulation of ARF GTPase activity (GO:0032312)2.77106050
118alditol metabolic process (GO:0019400)2.76446920
119positive regulation of endothelial cell differentiation (GO:0045603)2.71752198
120meiotic cell cycle process (GO:1903046)2.68798826
121cilium organization (GO:0044782)2.68422178
122GTP biosynthetic process (GO:0006183)2.67024356
123regulation of cilium assembly (GO:1902017)2.66909181
124mitochondrion degradation (GO:0000422)2.64792146
125cellular component assembly involved in morphogenesis (GO:0010927)2.60834490
126axoneme assembly (GO:0035082)2.58792736
127cilium assembly (GO:0042384)2.57774949
128microtubule-based movement (GO:0007018)2.51790329
129membrane protein intracellular domain proteolysis (GO:0031293)2.50436303
130cilium morphogenesis (GO:0060271)2.47281703
131negative regulation of gene expression, epigenetic (GO:0045814)2.45080520
132peptidyl-glutamic acid modification (GO:0018200)2.37242537
133centriole assembly (GO:0098534)2.36880522
134cell wall macromolecule catabolic process (GO:0016998)14.5528275
135cell wall macromolecule metabolic process (GO:0044036)14.5528275
136* sperm motility (GO:0030317)13.8745214
137acrosome reaction (GO:0007340)12.9083446
138fusion of sperm to egg plasma membrane (GO:0007342)12.7098930
139acrosome assembly (GO:0001675)11.8982342
140sperm-egg recognition (GO:0035036)11.7681095
141binding of sperm to zona pellucida (GO:0007339)10.8484730
142cell-cell recognition (GO:0009988)10.6140081
143multicellular organism reproduction (GO:0032504)10.3571581
144spermatid development (GO:0007286)10.0812391
145response to pheromone (GO:0019236)10.0373089

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.68892383
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.73871912
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.06429558
4EZH2_22144423_ChIP-Seq_EOC_Human4.01778673
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.76144460
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.48497156
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.11587287
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.86447502
9STAT6_21828071_ChIP-Seq_BEAS2B_Human2.77523155
10VDR_22108803_ChIP-Seq_LS180_Human2.49908252
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.47821630
12GATA1_26923725_Chip-Seq_HPCs_Mouse2.26243397
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.25573311
14ELF1_20517297_ChIP-Seq_JURKAT_Human2.18651299
15CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.13876877
16EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.11138137
17FLI1_27457419_Chip-Seq_LIVER_Mouse2.06560889
18VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.04218908
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.98909567
20ZNF274_21170338_ChIP-Seq_K562_Hela1.97997076
21* ERA_21632823_ChIP-Seq_H3396_Human1.95510075
22RAC3_21632823_ChIP-Seq_H3396_Human1.91742621
23KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.87715600
24DROSHA_22980978_ChIP-Seq_HELA_Human1.86936807
25RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.84345941
26NANOG_20526341_ChIP-Seq_ESCs_Human1.83248537
27EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.82403234
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82371162
29CTCF_27219007_Chip-Seq_Bcells_Human1.80754112
30FUS_26573619_Chip-Seq_HEK293_Human1.78794602
31FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.74935747
32BCL6_27268052_Chip-Seq_Bcells_Human1.73238949
33STAT1_17558387_ChIP-Seq_HELA_Human1.72847657
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.72797108
35PCGF2_27294783_Chip-Seq_ESCs_Mouse1.71705431
36SOX2_22085726_ChIP-Seq_NPCs_Mouse1.70127532
37MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.69907660
38UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.68030141
39E2F1_20622854_ChIP-Seq_HELA_Human1.67030248
40GATA3_21867929_ChIP-Seq_CD8_Mouse1.65513291
41TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65265132
42TDRD3_21172665_ChIP-Seq_MCF-7_Human1.64690695
43SMC4_20622854_ChIP-Seq_HELA_Human1.63433551
44TAF2_19829295_ChIP-Seq_ESCs_Human1.61499893
45P68_20966046_ChIP-Seq_HELA_Human1.58412853
46ER_23166858_ChIP-Seq_MCF-7_Human1.58118029
47MYC_19829295_ChIP-Seq_ESCs_Human1.56768772
48PHF8_20622854_ChIP-Seq_HELA_Human1.56268991
49AUTS2_25519132_ChIP-Seq_293T-REX_Human1.52749687
50GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.52113615
51KDM2B_26808549_Chip-Seq_REH_Human1.50328011
52ARNT_22903824_ChIP-Seq_MCF-7_Human1.48694428
53OCT4_20526341_ChIP-Seq_ESCs_Human1.48351389
54* TP63_22573176_ChIP-Seq_HFKS_Human1.47455265
55TAL1_26923725_Chip-Seq_HPCs_Mouse1.46983021
56RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.46711101
57LXR_22292898_ChIP-Seq_THP-1_Human1.46370387
58SMAD4_21741376_ChIP-Seq_EPCs_Human1.45626321
59FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.44874769
60WDR5_24793694_ChIP-Seq_LNCAP_Human1.44837386
61PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.42818460
62CBP_20019798_ChIP-Seq_JUKART_Human1.41430603
63IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41430603
64REST_21632747_ChIP-Seq_MESCs_Mouse1.39092119
65PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.38890882
66AR_25329375_ChIP-Seq_VCAP_Human1.38721141
67CBX2_22325352_ChIP-Seq_293T-Rex_Human1.38089556
68CBX2_27304074_Chip-Seq_ESCs_Mouse1.38035062
69P53_21459846_ChIP-Seq_SAOS-2_Human1.37506575
70SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.37410258
71HNFA_21074721_ChIP-Seq_CACO-2_Human1.37291327
72P300_27268052_Chip-Seq_Bcells_Human1.37054394
73TP53_18474530_ChIP-ChIP_U2OS_Human1.37025054
74SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.36125929
75KAP1_22055183_ChIP-Seq_ESCs_Mouse1.34487799
76SUZ12_27294783_Chip-Seq_ESCs_Mouse1.34012644
77RBPJ_21746931_ChIP-Seq_IB4_Human1.33937063
78CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.33284348
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33019387
80LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.32909605
81GATA3_21878914_ChIP-Seq_MCF-7_Human1.31231924
82SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.30042085
83PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.29833498
84GATA3_21867929_ChIP-Seq_TH1_Mouse1.29364321
85TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.29162766
86MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29052552
87SMAD3_21741376_ChIP-Seq_ESCs_Human1.28918779
88RUNX_20019798_ChIP-Seq_JUKART_Human1.28333251
89ETV1_20927104_ChIP-Seq_GIST48_Human1.28047987
90NFE2_27457419_Chip-Seq_LIVER_Mouse1.27308316
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25554170
92CEBPB_22108803_ChIP-Seq_LS180_Human1.25482434
93P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.24450485
94GF1_26923725_Chip-Seq_HPCs_Mouse1.24446255
95RAD21_21589869_ChIP-Seq_MESCs_Mouse1.23837343
96CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21125397
97SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20468997
98PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20059083
99SMAD3_21741376_ChIP-Seq_EPCs_Human1.19949653
100FLI1_21867929_ChIP-Seq_TH2_Mouse1.19827013
101SA1_27219007_Chip-Seq_Bcells_Human1.19518699
102P300_19829295_ChIP-Seq_ESCs_Human1.18988006
103CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.18961425
104ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18484830
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18394778
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18394778
107ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18375867
108NFYB_21822215_ChIP-Seq_K562_Human1.16774248
109NANOG_18555785_Chip-Seq_ESCs_Mouse1.16653757
110TP63_19390658_ChIP-ChIP_HaCaT_Human1.16090466
111SPI1_26923725_Chip-Seq_HPCs_Mouse1.15128791
112ERG_20517297_ChIP-Seq_VCAP_Human1.14726360
113SMRT_27268052_Chip-Seq_Bcells_Human1.14718370
114TBL1_22424771_ChIP-Seq_293T_Human1.14597419
115SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14365974
116SMAD4_21741376_ChIP-Seq_HESCs_Human1.14229616
117ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.14075503
118NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.13660699
119PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.12142675
120TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11182621
121RUNX1_26923725_Chip-Seq_HPCs_Mouse1.10872559
122TET1_21451524_ChIP-Seq_MESCs_Mouse1.10762826
123PHF8_20622853_ChIP-Seq_HELA_Human1.10120136
124EZH2_27294783_Chip-Seq_ESCs_Mouse1.09625813
125RXRA_24833708_ChIP-Seq_LIVER_Mouse1.09574063
126KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09442400
127GATA6_21074721_ChIP-Seq_CACO-2_Human1.09268728
128GATA1_19941827_ChIP-Seq_MEL86_Mouse1.08874467
129SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.08697969
130CRX_20693478_ChIP-Seq_RETINA_Mouse1.08321652
131MYC_27129775_Chip-Seq_CORNEA_Mouse1.07776125
132ESET_19884257_ChIP-Seq_ESCs_Mouse1.06726430
133EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06183701
134P53_22387025_ChIP-Seq_ESCs_Mouse1.05406361
135EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.05345501
136THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05227299
137RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.05192610
138RARA_24833708_ChIP-Seq_LIVER_Mouse1.05108035
139OCT4_18555785_Chip-Seq_ESCs_Mouse1.04097710
140SA1_27219007_Chip-Seq_ERYTHROID_Human1.03220250
141CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03215452
142TAF15_26573619_Chip-Seq_HEK293_Human1.02958351
143YY1_22570637_ChIP-Seq_MALME-3M_Human1.02826842
144CMYC_18555785_Chip-Seq_ESCs_Mouse1.02285073
145HOXB7_26014856_ChIP-Seq_BT474_Human1.01735771
146RUNX2_22187159_ChIP-Seq_PCA_Human1.01497859
147PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.01139723
148SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00167641
149SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99872229
150PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99871623
151CSB_26484114_Chip-Seq_FIBROBLAST_Human0.99529792
152SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99310818
153* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.99216915
154NANOG_19829295_ChIP-Seq_ESCs_Human0.98870507
155SOX2_19829295_ChIP-Seq_ESCs_Human0.98870507
156KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.98823832
157NFYA_21822215_ChIP-Seq_K562_Human0.98452691
158LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98356245
159EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97885951
160GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.97761493
161NFIB_24661679_ChIP-Seq_LUNG_Mouse0.97460588
162E2F1_17053090_ChIP-ChIP_MCF-7_Human0.97359296
163OCT1_27270436_Chip-Seq_PROSTATE_Human0.97280702
164PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96935045
165MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96303478
166CTCF_20526341_ChIP-Seq_ESCs_Human0.95829391
167ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94113593
168P300_18555785_Chip-Seq_ESCs_Mouse0.93952448
169KLF4_18555785_Chip-Seq_ESCs_Mouse0.93604079
170SOX9_26525672_Chip-Seq_HEART_Mouse0.93231927
171BCOR_27268052_Chip-Seq_Bcells_Human0.92986552
172OCT4_21477851_ChIP-Seq_ESCs_Mouse0.92292099
173SOX11_22085726_ChIP-Seq_ESNs_Mouse0.92215697
174ZFP57_27257070_Chip-Seq_ESCs_Mouse0.91348536

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0003698_abnormal_male_reproductive5.93841276
2MP0001929_abnormal_gametogenesis5.53928495
3MP0008877_abnormal_DNA_methylation3.55670006
4MP0005670_abnormal_white_adipose3.32504855
5MP0002161_abnormal_fertility/fecundity3.26736266
6MP0002210_abnormal_sex_determination3.21193657
7MP0001145_abnormal_male_reproductive2.73877078
8MP0000678_abnormal_parathyroid_gland2.73657105
9MP0000653_abnormal_sex_gland2.35962070
10MP0003718_maternal_effect2.13819239
11MP0005379_endocrine/exocrine_gland_phen2.00354217
12MP0005410_abnormal_fertilization16.9409342
13MP0002160_abnormal_reproductive_system1.86671024
14MP0005423_abnormal_somatic_nervous1.78886932
15MP0003646_muscle_fatigue1.74166078
16MP0002249_abnormal_larynx_morphology1.72699258
17MP0004233_abnormal_muscle_weight1.61897283
18MP0002653_abnormal_ependyma_morphology1.54203697
19MP0004510_myositis1.52767862
20MP0009053_abnormal_anal_canal1.52367851
21MP0001486_abnormal_startle_reflex1.45878232
22MP0001485_abnormal_pinna_reflex1.35542460
23MP0002735_abnormal_chemical_nociception1.35002527
24MP0005310_abnormal_salivary_gland1.28847452
25MP0002138_abnormal_hepatobiliary_system1.24542400
26MP0005248_abnormal_Harderian_gland1.18791880
27MP0004859_abnormal_synaptic_plasticity1.17140001
28MP0002127_abnormal_cardiovascular_syste1.13627379
29MP0001765_abnormal_ion_homeostasis1.11524801
30MP0001984_abnormal_olfaction1.05552057
31MP0001963_abnormal_hearing_physiology1.03130514
32MP0005623_abnormal_meninges_morphology1.00958458
33MP0005395_other_phenotype0.95712065
34MP0005647_abnormal_sex_gland0.94182018
35MP0000681_abnormal_thyroid_gland0.94087754
36MP0000026_abnormal_inner_ear0.93288370
37MP0005389_reproductive_system_phenotype0.91783445
38MP0002234_abnormal_pharynx_morphology0.90887833
39MP0005451_abnormal_body_composition0.89439461
40MP0002282_abnormal_trachea_morphology0.82003174
41MP0002733_abnormal_thermal_nociception0.80410413
42MP0000049_abnormal_middle_ear0.80395910
43MP0000516_abnormal_urinary_system0.78685403
44MP0005367_renal/urinary_system_phenotyp0.78685403
45MP0000955_abnormal_spinal_cord0.77633785
46MP0008058_abnormal_DNA_repair0.77538795
47MP0001879_abnormal_lymphatic_vessel0.73149902
48MP0002067_abnormal_sensory_capabilities0.71066725
49MP0004085_abnormal_heartbeat0.70317058
50MP0005083_abnormal_biliary_tract0.69489797
51MP0003011_delayed_dark_adaptation0.68099679
52MP0009046_muscle_twitch0.66018708
53MP0005636_abnormal_mineral_homeostasis0.65510129
54MP0002557_abnormal_social/conspecific_i0.64592365
55MP0005666_abnormal_adipose_tissue0.63403609
56MP0003115_abnormal_respiratory_system0.60604558
57MP0002736_abnormal_nociception_after0.58182237
58MP0005167_abnormal_blood-brain_barrier0.58083576
59MP0006036_abnormal_mitochondrial_physio0.57990095
60MP0001764_abnormal_homeostasis0.54874779
61MP0004036_abnormal_muscle_relaxation0.54547256
62MP0005535_abnormal_body_temperature0.53445520
63MP0001970_abnormal_pain_threshold0.52940518
64MP0001324_abnormal_eye_pigmentation0.52593046
65MP0001905_abnormal_dopamine_level0.50866503
66MP0004484_altered_response_of0.49655140
67MP0001501_abnormal_sleep_pattern0.49491622
68MP0009745_abnormal_behavioral_response0.48721103
69MP0008995_early_reproductive_senescence0.48637217
70MP0003880_abnormal_central_pattern0.47810889
71MP0008961_abnormal_basal_metabolism0.47791154
72MP0001666_abnormal_nutrient_absorption0.46658793
73MP0009697_abnormal_copulation0.46266532
74MP0003329_amyloid_beta_deposits0.46234878
75MP0000003_abnormal_adipose_tissue0.45968713
76MP0003878_abnormal_ear_physiology0.44948792
77MP0005377_hearing/vestibular/ear_phenot0.44948792
78MP0003119_abnormal_digestive_system0.44628736
79MP0002734_abnormal_mechanical_nocicepti0.44407203
80MP0003137_abnormal_impulse_conducting0.43832104
81MP0006292_abnormal_olfactory_placode0.43061198
82MP0000358_abnormal_cell_content/0.42901449
83MP0003077_abnormal_cell_cycle0.42071090
84MP0003699_abnormal_female_reproductive0.41983972
85MP0005084_abnormal_gallbladder_morpholo0.41629555
86MP0001440_abnormal_grooming_behavior0.41292827
87MP0000249_abnormal_blood_vessel0.39371821
88MP0002269_muscular_atrophy0.39130041
89MP0000470_abnormal_stomach_morphology0.37943842
90MP0005253_abnormal_eye_physiology0.37404285
91MP0009115_abnormal_fat_cell0.37284635
92MP0001968_abnormal_touch/_nociception0.36920164
93MP0002928_abnormal_bile_duct0.35693794
94MP0010094_abnormal_chromosome_stability0.35544427
95MP0003635_abnormal_synaptic_transmissio0.35384832
96MP0000569_abnormal_digit_pigmentation0.35107742
97MP0000534_abnormal_ureter_morphology0.35074545
98MP0001293_anophthalmia0.34730512
99MP0003172_abnormal_lysosome_physiology0.34671185
100MP0005551_abnormal_eye_electrophysiolog0.34640637
101MP0002254_reproductive_system_inflammat0.33924788
102MP0002139_abnormal_hepatobiliary_system0.33333382
103MP0005408_hypopigmentation0.32969736
104MP0000613_abnormal_salivary_gland0.32588944
105MP0003936_abnormal_reproductive_system0.32407090
106MP0006035_abnormal_mitochondrial_morpho0.32025525
107MP0003633_abnormal_nervous_system0.31956348
108MP0000467_abnormal_esophagus_morphology0.31896065
109MP0001545_abnormal_hematopoietic_system0.31786404
110MP0005397_hematopoietic_system_phenotyp0.31786404
111MP0003183_abnormal_peptide_metabolism0.31712878
112MP0009278_abnormal_bone_marrow0.31098240
113MP0000230_abnormal_systemic_arterial0.30779882
114MP0004133_heterotaxia0.30291468
115MP0004019_abnormal_vitamin_homeostasis0.30242485
116MP0004811_abnormal_neuron_physiology0.29465322
117MP0006082_CNS_inflammation0.28843635
118MP0002822_catalepsy0.28482500
119MP0003787_abnormal_imprinting0.28319925
120MP0002971_abnormal_brown_adipose0.26504539
121MP0003942_abnormal_urinary_system0.26405207
122MP0005391_vision/eye_phenotype0.26396187
123MP0002169_no_abnormal_phenotype0.26142501
124MP0002873_normal_phenotype0.26031449
125MP0003950_abnormal_plasma_membrane0.25588463
126MP0003879_abnormal_hair_cell0.24653998
127MP0003948_abnormal_gas_homeostasis0.23311517
128MP0003631_nervous_system_phenotype0.23089322
129MP0004742_abnormal_vestibular_system0.23079936
130MP0003111_abnormal_nucleus_morphology0.22920384
131MP0002693_abnormal_pancreas_physiology0.22374322
132MP0004270_analgesia0.21957287
133MP0000604_amyloidosis0.21608296
134MP0005375_adipose_tissue_phenotype0.21578839
135MP0001119_abnormal_female_reproductive0.20597438
136MP0001348_abnormal_lacrimal_gland0.20271850
137MP0003959_abnormal_lean_body0.19990466
138MP0002152_abnormal_brain_morphology0.19537890
139MP0008569_lethality_at_weaning0.19067253
140MP0003861_abnormal_nervous_system0.18996631
141MP0004043_abnormal_pH_regulation0.18815911
142MP0001730_embryonic_growth_arrest0.18181546
143MP0004145_abnormal_muscle_electrophysio0.17369579
144MP0002102_abnormal_ear_morphology0.15854845
145MP0002108_abnormal_muscle_morphology0.15122267
146MP0000001_mammalian_phenotype0.14973944
147MP0002295_abnormal_pulmonary_circulatio0.14970761
148MP0002909_abnormal_adrenal_gland0.14720594
149MP0002229_neurodegeneration0.14625615
150MP0005319_abnormal_enzyme/_coenzyme0.14465727
151MP0001849_ear_inflammation0.14414326
152MP0000920_abnormal_myelination0.14024760
153MP0002272_abnormal_nervous_system0.13024131
154MP0002796_impaired_skin_barrier0.12874480
155MP0000751_myopathy0.12488916
156MP0002132_abnormal_respiratory_system0.12289689
157MP0002092_abnormal_eye_morphology0.11599165
158MP0002572_abnormal_emotion/affect_behav0.11296432
159MP0001727_abnormal_embryo_implantation0.10476253

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.29068826
2Abnormal respiratory epithelium morphology (HP:0012253)9.27898031
3Abnormal respiratory motile cilium morphology (HP:0005938)9.27898031
4Severe visual impairment (HP:0001141)8.78032005
5Rhinitis (HP:0012384)7.38186256
6Chronic bronchitis (HP:0004469)7.37278656
7Abnormal ciliary motility (HP:0012262)7.25138508
8Infertility (HP:0000789)7.11631437
9Nasal polyposis (HP:0100582)6.25134107
10Attenuation of retinal blood vessels (HP:0007843)5.31783221
11Bony spicule pigmentary retinopathy (HP:0007737)5.29009350
12Abnormality of the nasal mucosa (HP:0000433)5.10170509
13Male infertility (HP:0003251)4.83174223
14Resting tremor (HP:0002322)4.53800265
15Bronchitis (HP:0012387)4.40770169
16Bronchiectasis (HP:0002110)4.33411890
17Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.32292939
18Abnormal rod and cone electroretinograms (HP:0008323)4.26883226
19Hyperkalemia (HP:0002153)4.23645547
20Nephronophthisis (HP:0000090)4.14381480
21Chronic hepatic failure (HP:0100626)4.13031434
22Abnormality of macular pigmentation (HP:0008002)4.03240789
23Facial shape deformation (HP:0011334)3.98871718
24Potter facies (HP:0002009)3.98871718
25Hypoplastic ischia (HP:0003175)3.88302971
26Abnormal spermatogenesis (HP:0008669)3.78769569
27Enlarged epiphyses (HP:0010580)3.60309433
28Aplasia/Hypoplasia of the earlobes (HP:0009906)3.56784161
29Cone-rod dystrophy (HP:0000548)3.55792964
30Abnormality of the ischium (HP:0003174)3.43209204
31Unilateral renal agenesis (HP:0000122)3.32271699
32Recurrent sinusitis (HP:0011108)3.18879426
33Recurrent otitis media (HP:0000403)3.17919345
34Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.16116472
35Abnormality of the renal medulla (HP:0100957)3.14163641
36Hypoplasia of the thymus (HP:0000778)3.09134943
37Postural instability (HP:0002172)2.97391410
38Progressive sensorineural hearing impairment (HP:0000408)2.92358837
39Tubulointerstitial nephritis (HP:0001970)2.88567750
40Abnormality of the aortic arch (HP:0012303)2.82919132
41Tubular atrophy (HP:0000092)2.71666329
42Progressive cerebellar ataxia (HP:0002073)2.68149316
43Hypoalphalipoproteinemia (HP:0003233)2.66949428
44Molar tooth sign on MRI (HP:0002419)2.64494153
45Abnormality of midbrain morphology (HP:0002418)2.64494153
46Generalized aminoaciduria (HP:0002909)2.61167644
47Cholecystitis (HP:0001082)2.59352698
48Abnormal gallbladder physiology (HP:0012438)2.59352698
49Tubulointerstitial abnormality (HP:0001969)2.53156171
50Medial flaring of the eyebrow (HP:0010747)2.49437626
51Abnormality of potassium homeostasis (HP:0011042)2.49434636
52Truncal obesity (HP:0001956)2.48856761
53Azoospermia (HP:0000027)2.46868912
54Amelogenesis imperfecta (HP:0000705)2.46764660
55Abnormality of dental color (HP:0011073)2.44610009
56Impulsivity (HP:0100710)2.44000641
57Recurrent bronchitis (HP:0002837)2.43097844
58Abnormality of the costochondral junction (HP:0000919)2.32555951
59Abnormality of the parathyroid morphology (HP:0011766)2.31867762
60Congenital malformation of the right heart (HP:0011723)2.28683551
61Double outlet right ventricle (HP:0001719)2.28683551
62Dyschromatopsia (HP:0007641)2.23975865
63Flattened epiphyses (HP:0003071)2.21547862
64Insulin-resistant diabetes mellitus (HP:0000831)2.20832810
65Ventricular tachycardia (HP:0004756)2.20516795
66Portal hypertension (HP:0001409)2.19287550
67Renovascular hypertension (HP:0100817)2.17372841
68Decreased central vision (HP:0007663)2.16678600
69Aplasia/Hypoplasia of the sacrum (HP:0008517)2.15886590
70Osteomalacia (HP:0002749)2.15457240
71Menstrual irregularities (HP:0000858)2.11282450
72Tubulointerstitial fibrosis (HP:0005576)2.09663219
73Epiphyseal dysplasia (HP:0002656)2.07767249
74Hyponatremia (HP:0002902)2.06661099
75Choroideremia (HP:0001139)2.06391294
76Focal segmental glomerulosclerosis (HP:0000097)2.05470345
77Gonadotropin excess (HP:0000837)2.04586126
78Tetany (HP:0001281)2.02595702
79Abnormality of the epiphysis of the femoral head (HP:0010574)2.01735322
80Abnormality of the pubic bones (HP:0003172)2.00596283
81Absent/shortened dynein arms (HP:0200106)13.4682075
82Dynein arm defect of respiratory motile cilia (HP:0012255)13.4682075
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8314289
84Abnormality of the hepatic vasculature (HP:0006707)1.99337000
85Widely patent fontanelles and sutures (HP:0004492)1.98000824
86Hyperthyroidism (HP:0000836)1.97862422
87Spastic paraparesis (HP:0002313)1.96218730
88Hypoparathyroidism (HP:0000829)1.90424632
89Myokymia (HP:0002411)1.90376579
90Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.87759233
91Abnormality of femoral epiphyses (HP:0006499)1.87759233
92Progressive hearing impairment (HP:0001730)1.87474470
93Abnormal drinking behavior (HP:0030082)1.86588257
94Polydipsia (HP:0001959)1.86588257
95Flat capital femoral epiphysis (HP:0003370)1.85125065
96Bowel incontinence (HP:0002607)1.80253289
97Hyperuricemia (HP:0002149)1.79308761
98Increased purine levels (HP:0004368)1.79308761
99Abnormality of the femoral head (HP:0003368)1.78868617
100Spastic tetraparesis (HP:0001285)1.77681418
101Abnormality of the renal cortex (HP:0011035)1.76183649
102Abnormality of renal excretion (HP:0011036)1.75266701
103Stage 5 chronic kidney disease (HP:0003774)1.74949413
104Hemorrhage of the eye (HP:0011885)1.73885469
105Decreased electroretinogram (ERG) amplitude (HP:0000654)1.67919875
106Congenital hepatic fibrosis (HP:0002612)1.66431409
107Bile duct proliferation (HP:0001408)1.65462645
108Abnormal biliary tract physiology (HP:0012439)1.65462645
109Asymmetric septal hypertrophy (HP:0001670)1.65078393
110Postaxial foot polydactyly (HP:0001830)1.64843996
111Bell-shaped thorax (HP:0001591)1.57880721
112Neurofibrillary tangles (HP:0002185)1.57068034
113Bundle branch block (HP:0011710)1.55769203
114Heterotopia (HP:0002282)1.55556795
115Aplasia/Hypoplasia of the lens (HP:0008063)1.55472205
116Easy fatigability (HP:0003388)1.51099674
117Sensory axonal neuropathy (HP:0003390)1.49917672
118Hypoplasia of the capital femoral epiphysis (HP:0003090)1.49248907
119Oculomotor apraxia (HP:0000657)1.46929042
120Abnormality of permanent molar morphology (HP:0011071)1.46228234
121Abnormality of the dental root (HP:0006486)1.46228234
122Taurodontia (HP:0000679)1.46228234
123Fatigable weakness (HP:0003473)1.46060297
124Abnormality of the neuromuscular junction (HP:0003398)1.46060297
125Abnormal urine output (HP:0012590)1.45807989
126Exercise-induced myalgia (HP:0003738)1.43585857
127Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.42605847
128Abnormality of the dental pulp (HP:0006479)1.38175702
129Renal dysplasia (HP:0000110)1.36468760
130Constricted visual fields (HP:0001133)1.36306147
131Postaxial hand polydactyly (HP:0001162)1.35791183
132Abnormality of molar (HP:0011077)1.34776562
133Abnormality of molar morphology (HP:0011070)1.34776562
134Short ribs (HP:0000773)1.33962872
135Myoglobinuria (HP:0002913)1.33767984
136Rhabdomyolysis (HP:0003201)1.29159667
137Cystic liver disease (HP:0006706)1.27073424
138Cerebellar dysplasia (HP:0007033)1.26697702
139Abnormality of dentin (HP:0010299)1.25564137
140Facial cleft (HP:0002006)1.25391229
141Chronic sinusitis (HP:0011109)1.24833988
142Congenital primary aphakia (HP:0007707)1.24568353
143Gait imbalance (HP:0002141)1.24293989
144Type 2 muscle fiber atrophy (HP:0003554)1.23015925
145Cerebral inclusion bodies (HP:0100314)1.22422530
146Loss of speech (HP:0002371)1.22061052
147Transposition of the great arteries (HP:0001669)1.21503878
148Abnormal connection of the cardiac segments (HP:0011545)1.21503878
149Abnormal ventriculo-arterial connection (HP:0011563)1.21503878
150Nephropathy (HP:0000112)1.19595309
151Optic nerve hypoplasia (HP:0000609)1.19337295
152Abnormality of saccadic eye movements (HP:0000570)1.18404970
153Polyuria (HP:0000103)1.18067273
154Hypercholesterolemia (HP:0003124)1.17698538
155Neoplasm of the heart (HP:0100544)1.17026895
156Generalized muscle weakness (HP:0003324)1.15571098
157Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.15351892
158Absent epiphyses (HP:0010577)1.15351892
159Hemiparesis (HP:0001269)1.13732135

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.13649431
2PDK48.13649431
3TESK16.86155296
4PDK25.24398464
5DDR24.84069391
6PRKD34.78947547
7ICK4.74592996
8MAP4K24.13017943
9INSRR3.76271919
10BRD43.14587039
11PLK23.07884160
12PTK2B2.14763974
13STK382.02623230
14WNK41.94283375
15STK391.90980603
16PIK3CG1.71183725
17MST1R1.68228126
18DYRK1B1.60860336
19NEK21.60159031
20CDK121.34818911
21PDK11.33014246
22PNCK1.32424829
23CDK71.28857531
24MAP3K91.25269602
25KSR21.12549793
26LATS21.05165208
27DYRK31.00902024
28IRAK10.93115574
29UHMK10.89130040
30PDPK10.88819535
31CAMK1D0.86729966
32SIK20.78886315
33STK38L0.78327687
34MAPK150.77186617
35MAP3K110.77016890
36PINK10.74329194
37RIPK40.74253277
38PRKAA20.72907823
39AKT30.72267902
40WNK10.68414537
41RPS6KA20.67425169
42STK30.64471886
43TYRO30.64370361
44LMTK20.64310887
45EEF2K0.63872553
46IRAK20.61940321
47MAP2K20.61812591
48CCNB10.60712357
49MAP3K80.60434026
50TTK0.60275822
51MAP2K60.59844702
52MAP3K20.59291053
53PASK0.55729167
54CHEK20.54375987
55CAMK10.53058960
56MUSK0.52978129
57CDK30.49808598
58ROCK10.49186377
59NTRK20.47187000
60MARK10.44700991
61BMPR1B0.43640767
62PRKCG0.42271804
63MAPK10.39505901
64TESK20.39437834
65SGK2230.38683400
66SGK4940.38683400
67CAMK40.37973852
68LATS10.37837980
69MAP3K10.36327878
70RPS6KC10.35962889
71RPS6KL10.35962889
72PAK10.34474332
73NTRK30.34189198
74RPS6KA60.33874449
75TIE10.32358204
76ARAF0.32042646
77CHEK10.29980919
78SGK10.28756342
79BLK0.26538579
80MAPKAPK50.26135413
81BRSK10.25026953
82MAPK100.23621308
83MAPK140.23083404
84ATM0.22995080
85MARK20.21859372
86PRKCQ0.20949445
87MAP3K40.20826719
88PLK40.20659453
89PRKCZ0.20077065
90CAMK1G0.19827963
91PAK20.19184261
92MAP3K100.18755795
93AKT10.18193931
94ATR0.18082172
95PRKAA10.17621693
96MAPK110.17353431
97MET0.16908561
98PKN10.16685269
99MTOR0.15822936
100MARK30.14693713
101RPS6KB10.14650652
102CASK0.14125531
103OXSR10.13729621
104PAK40.13525459
105IKBKB0.12757581
106CSF1R0.12508876
107BRSK20.12235032
108FER0.12132105
109BRAF0.11997229
110CDK150.11941979
111PLK10.11517348
112FRK0.11454079
113PRKG20.11370947
114RPS6KA10.11302693
115STK100.10916665
116NEK60.10893944
117CAMKK10.09979156
118CDK180.09729423
119CSNK2A10.09104862
120MINK10.08810101
121PIM10.08560816
122CHUK0.08444815
123CDK11A0.08276596
124CAMK2A0.08097228
125PRKCD0.07787940
126MAPK90.07677073
127MAP3K50.07215550
128GSK3B0.06749605
129WEE10.05206091
130CDK140.05154550
131MAP3K70.05127394
132TNIK0.04473456
133YES10.03950382
134SGK20.03703509
135PRKG10.03557814
136PRKACG0.03430129
137PRKCA0.03289668
138PRKCB0.03120403
139CSNK2A20.02831891
140MAPK80.02024321
141CDC70.01612071
142CDK10.00377455
143GSK3A-0.0531420
144PAK6-0.0514450
145CSNK1D-0.0490248
146CDK6-0.0444118
147EPHA4-0.0374756
148WNK3-0.0339605
149CLK1-0.0329139
150EGFR-0.0302248
151RPS6KA3-0.0257579
152STK11-0.0248526
153PRKACB-0.0221100
154CDK4-0.0209069
155PRKACA-0.0202738
156AURKA-0.0053476
157CDK2-0.0048863

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.50427174
2Fatty acid biosynthesis_Homo sapiens_hsa000614.93193826
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.31810143
4Olfactory transduction_Homo sapiens_hsa047403.67216691
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.40539407
6Linoleic acid metabolism_Homo sapiens_hsa005913.34333563
7Vitamin B6 metabolism_Homo sapiens_hsa007503.28700395
8Pyruvate metabolism_Homo sapiens_hsa006203.21631045
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.93892751
10Butanoate metabolism_Homo sapiens_hsa006502.84663114
11Glucagon signaling pathway_Homo sapiens_hsa049222.44567654
12Propanoate metabolism_Homo sapiens_hsa006402.41022730
13Carbohydrate digestion and absorption_Homo sapiens_hsa049732.40820193
14Allograft rejection_Homo sapiens_hsa053302.28912555
15Type I diabetes mellitus_Homo sapiens_hsa049402.25662968
16Autoimmune thyroid disease_Homo sapiens_hsa053202.21310504
17Graft-versus-host disease_Homo sapiens_hsa053322.13711285
18Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.12668148
19Basal transcription factors_Homo sapiens_hsa030222.08761756
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.07690237
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.93051615
22Glycerolipid metabolism_Homo sapiens_hsa005611.87034841
23Selenocompound metabolism_Homo sapiens_hsa004501.86824780
24Glycerophospholipid metabolism_Homo sapiens_hsa005641.84226979
25PPAR signaling pathway_Homo sapiens_hsa033201.78180693
26Amphetamine addiction_Homo sapiens_hsa050311.69476898
27Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.64149935
28Type II diabetes mellitus_Homo sapiens_hsa049301.61137498
29Fat digestion and absorption_Homo sapiens_hsa049751.60961807
30Ether lipid metabolism_Homo sapiens_hsa005651.59643055
31Viral myocarditis_Homo sapiens_hsa054161.59541678
32Mineral absorption_Homo sapiens_hsa049781.57338188
33Oocyte meiosis_Homo sapiens_hsa041141.52697484
34Phenylalanine metabolism_Homo sapiens_hsa003601.49352747
35Cardiac muscle contraction_Homo sapiens_hsa042601.47910963
36Glycosaminoglycan degradation_Homo sapiens_hsa005311.46253378
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.45561441
38Fructose and mannose metabolism_Homo sapiens_hsa000511.42980209
39Fatty acid degradation_Homo sapiens_hsa000711.38644509
40Fatty acid metabolism_Homo sapiens_hsa012121.37478033
41Collecting duct acid secretion_Homo sapiens_hsa049661.34590245
42Arginine and proline metabolism_Homo sapiens_hsa003301.30282632
43Carbon metabolism_Homo sapiens_hsa012001.22256377
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.21526328
45Pentose phosphate pathway_Homo sapiens_hsa000301.20763965
46Glutathione metabolism_Homo sapiens_hsa004801.20521017
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20206166
48Renin secretion_Homo sapiens_hsa049241.04826614
49Arachidonic acid metabolism_Homo sapiens_hsa005901.03920102
50Antigen processing and presentation_Homo sapiens_hsa046121.02637251
51Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02581263
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00104491
53Phototransduction_Homo sapiens_hsa047440.99085925
54Dorso-ventral axis formation_Homo sapiens_hsa043200.98118082
55Purine metabolism_Homo sapiens_hsa002300.97256539
56Hedgehog signaling pathway_Homo sapiens_hsa043400.95673945
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.95333182
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.94614026
59Insulin secretion_Homo sapiens_hsa049110.93061954
60Fanconi anemia pathway_Homo sapiens_hsa034600.92715047
61Influenza A_Homo sapiens_hsa051640.91001430
62Morphine addiction_Homo sapiens_hsa050320.88294769
63Huntingtons disease_Homo sapiens_hsa050160.87753901
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86828526
65Adipocytokine signaling pathway_Homo sapiens_hsa049200.83617782
66Arginine biosynthesis_Homo sapiens_hsa002200.83278055
67Legionellosis_Homo sapiens_hsa051340.82903936
68Chemical carcinogenesis_Homo sapiens_hsa052040.80943025
69Systemic lupus erythematosus_Homo sapiens_hsa053220.79418186
70Bile secretion_Homo sapiens_hsa049760.79411259
71Thyroid hormone synthesis_Homo sapiens_hsa049180.77138496
72Nicotine addiction_Homo sapiens_hsa050330.76831418
73mRNA surveillance pathway_Homo sapiens_hsa030150.71329880
74Pancreatic secretion_Homo sapiens_hsa049720.68546412
75cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67135714
76Long-term potentiation_Homo sapiens_hsa047200.65444913
77Synaptic vesicle cycle_Homo sapiens_hsa047210.65271878
78Estrogen signaling pathway_Homo sapiens_hsa049150.64670066
79Salivary secretion_Homo sapiens_hsa049700.64270398
80Tyrosine metabolism_Homo sapiens_hsa003500.61140278
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60114643
82Renin-angiotensin system_Homo sapiens_hsa046140.59992785
83Biosynthesis of amino acids_Homo sapiens_hsa012300.58324364
84Aldosterone synthesis and secretion_Homo sapiens_hsa049250.57135940
85Retinol metabolism_Homo sapiens_hsa008300.56828610
86Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.56533429
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55692299
88Calcium signaling pathway_Homo sapiens_hsa040200.55405851
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52068702
90ABC transporters_Homo sapiens_hsa020100.52045274
91Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.49804787
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.49760358
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.49450668
94Alcoholism_Homo sapiens_hsa050340.49070235
95Inositol phosphate metabolism_Homo sapiens_hsa005620.47982574
96Gastric acid secretion_Homo sapiens_hsa049710.46577963
97MAPK signaling pathway_Homo sapiens_hsa040100.46374264
98Acute myeloid leukemia_Homo sapiens_hsa052210.46231600
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.45151683
100Protein digestion and absorption_Homo sapiens_hsa049740.44486405
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.44144234
102Endocytosis_Homo sapiens_hsa041440.42733777
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42382570
104RNA transport_Homo sapiens_hsa030130.41952480
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39600144
106Metabolic pathways_Homo sapiens_hsa011000.39427605
107Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38914935
108Cocaine addiction_Homo sapiens_hsa050300.38011592
109GABAergic synapse_Homo sapiens_hsa047270.36159943
110Sulfur metabolism_Homo sapiens_hsa009200.35058447
111AMPK signaling pathway_Homo sapiens_hsa041520.33406573
112Serotonergic synapse_Homo sapiens_hsa047260.32923152
113Salmonella infection_Homo sapiens_hsa051320.32900902
114Cholinergic synapse_Homo sapiens_hsa047250.32631183
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.32260709
116Tight junction_Homo sapiens_hsa045300.32018022
117cAMP signaling pathway_Homo sapiens_hsa040240.31457956
118Herpes simplex infection_Homo sapiens_hsa051680.30712626
119Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.30616690
120Viral carcinogenesis_Homo sapiens_hsa052030.28960011
121Circadian entrainment_Homo sapiens_hsa047130.28903201
122Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27843409
123Oxytocin signaling pathway_Homo sapiens_hsa049210.25916607
124Pyrimidine metabolism_Homo sapiens_hsa002400.25658613
125Taste transduction_Homo sapiens_hsa047420.23013785
126VEGF signaling pathway_Homo sapiens_hsa043700.22538376
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.21124949
128Rheumatoid arthritis_Homo sapiens_hsa053230.20966498
129Epstein-Barr virus infection_Homo sapiens_hsa051690.20133529
130Toxoplasmosis_Homo sapiens_hsa051450.19322862
131Prolactin signaling pathway_Homo sapiens_hsa049170.17965058
132Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.17153931
133Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.16285258
134Nitrogen metabolism_Homo sapiens_hsa009100.15795038
135Transcriptional misregulation in cancer_Homo sapiens_hsa052020.15053803
136B cell receptor signaling pathway_Homo sapiens_hsa046620.10919504
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.09658785
138Wnt signaling pathway_Homo sapiens_hsa043100.08730502
139Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.07561313
140HIF-1 signaling pathway_Homo sapiens_hsa040660.06399861
141Vibrio cholerae infection_Homo sapiens_hsa051100.06312951
142Basal cell carcinoma_Homo sapiens_hsa052170.04138999
143Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.03894525
144Glutamatergic synapse_Homo sapiens_hsa047240.03542416

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