PRMT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sequestering of actin monomers (GO:0042989)5.69729173
2neuron cell-cell adhesion (GO:0007158)5.43631301
3vocalization behavior (GO:0071625)4.84411301
4synaptic vesicle exocytosis (GO:0016079)4.72642503
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.64718657
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.26147570
7negative regulation of microtubule polymerization (GO:0031115)4.26043582
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.12619484
9regulation of synaptic vesicle exocytosis (GO:2000300)4.11821908
10neuron recognition (GO:0008038)4.07458154
11activated T cell proliferation (GO:0050798)3.97638655
12protein localization to synapse (GO:0035418)3.94011740
13glutamate secretion (GO:0014047)3.92237725
14regulation of glutamate receptor signaling pathway (GO:1900449)3.91625442
15synaptic vesicle maturation (GO:0016188)3.72892242
16neurotransmitter secretion (GO:0007269)3.71133875
17postsynaptic membrane organization (GO:0001941)3.69325801
18pyrimidine nucleobase catabolic process (GO:0006208)3.66966854
19positive regulation of synapse assembly (GO:0051965)3.64570405
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.63813650
21cell migration in hindbrain (GO:0021535)3.62917659
22positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.59103348
23regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.56533663
24regulation of synaptic vesicle transport (GO:1902803)3.54653816
25chaperone-mediated protein transport (GO:0072321)3.48704349
26regulation of synapse structural plasticity (GO:0051823)3.48702949
27negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.47197544
28negative regulation of cell killing (GO:0031342)3.47197544
29axonal fasciculation (GO:0007413)3.46637172
30presynaptic membrane assembly (GO:0097105)3.46284818
31synaptic vesicle docking involved in exocytosis (GO:0016081)3.38094587
32positive regulation of synaptic transmission, GABAergic (GO:0032230)3.37100284
33ATP hydrolysis coupled proton transport (GO:0015991)3.34867152
34energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.34867152
35positive regulation of mitochondrial fission (GO:0090141)3.33184311
36layer formation in cerebral cortex (GO:0021819)3.32990341
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.31142615
38neuron-neuron synaptic transmission (GO:0007270)3.30767685
39proline transport (GO:0015824)3.29530130
40ionotropic glutamate receptor signaling pathway (GO:0035235)3.26839459
41exploration behavior (GO:0035640)3.26019810
42presynaptic membrane organization (GO:0097090)3.22867767
43dendritic spine morphogenesis (GO:0060997)3.22785222
44locomotory exploration behavior (GO:0035641)3.20617796
45transferrin transport (GO:0033572)3.19846366
46glycosphingolipid biosynthetic process (GO:0006688)3.19426797
47positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.17901391
48neurotransmitter transport (GO:0006836)3.17891191
49Arp2/3 complex-mediated actin nucleation (GO:0034314)3.17365871
50synaptic vesicle endocytosis (GO:0048488)3.14992003
51positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.14044060
52dopamine biosynthetic process (GO:0042416)3.12773931
53synaptic transmission, glutamatergic (GO:0035249)3.11680107
54establishment of mitochondrion localization (GO:0051654)3.11503948
55negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.10722720
56mating behavior (GO:0007617)3.06636991
57neuronal action potential propagation (GO:0019227)3.06096565
58synapse assembly (GO:0007416)3.05340464
59regulation of neuronal synaptic plasticity (GO:0048168)3.04774037
60regulation of vesicle fusion (GO:0031338)3.02302899
61neurotransmitter-gated ion channel clustering (GO:0072578)3.01306280
62regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.99462149
63opioid receptor signaling pathway (GO:0038003)2.99280593
64glutamate receptor signaling pathway (GO:0007215)2.99020033
65regulation of glutamate secretion (GO:0014048)2.98910373
66platelet dense granule organization (GO:0060155)2.98145772
67behavioral response to ethanol (GO:0048149)2.98022558
68regulation of neurotransmitter levels (GO:0001505)2.97827613
69regulation of synaptic transmission, GABAergic (GO:0032228)2.97808878
70membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.97557876
71trivalent inorganic cation transport (GO:0072512)2.97105772
72ferric iron transport (GO:0015682)2.97105772
73regulation of long-term neuronal synaptic plasticity (GO:0048169)2.96281250
74gamma-aminobutyric acid signaling pathway (GO:0007214)2.96075037
75dendrite development (GO:0016358)2.94880310
76transmission of nerve impulse (GO:0019226)2.94714685
77regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.94099714
78actin nucleation (GO:0045010)2.94094033
79gamma-aminobutyric acid transport (GO:0015812)2.93116403
80regulation of synapse assembly (GO:0051963)2.92822383
81striatum development (GO:0021756)2.91417590
82nucleobase catabolic process (GO:0046113)2.91172478
83mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.90493373
84establishment of synaptic vesicle localization (GO:0097480)2.88714607
85synaptic vesicle transport (GO:0048489)2.88714607
86response to pheromone (GO:0019236)2.87621006
87mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.87608021
88ATP synthesis coupled proton transport (GO:0015986)2.86248184
89energy coupled proton transport, down electrochemical gradient (GO:0015985)2.86248184
90response to cocaine (GO:0042220)2.86021124
91membrane hyperpolarization (GO:0060081)2.85202749
92innervation (GO:0060384)2.84983249
93dendrite morphogenesis (GO:0048813)2.83798952
94startle response (GO:0001964)2.83478734
95regulation of synaptic transmission, dopaminergic (GO:0032225)2.82924178
96regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.82532553
97regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.82532553
98mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.82120734
99positive regulation of neurotransmitter transport (GO:0051590)2.82032194
100regulation of respiratory system process (GO:0044065)2.81800123
101regulation of feeding behavior (GO:0060259)2.79774417
102synaptic transmission, dopaminergic (GO:0001963)2.79483989
103regulation of cAMP-dependent protein kinase activity (GO:2000479)2.78219072
104regulation of neurotransmitter secretion (GO:0046928)2.77715742
105establishment of vesicle localization (GO:0051650)2.77541476
106regulation of dopamine metabolic process (GO:0042053)2.76712914
107regulation of catecholamine metabolic process (GO:0042069)2.76712914
108antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.76574379
109catecholamine transport (GO:0051937)2.76048602
110negative regulation of dendrite morphogenesis (GO:0050774)2.75382303
111regulation of synaptic transmission, glutamatergic (GO:0051966)2.75328683
112prepulse inhibition (GO:0060134)2.75187250
113protein localization to cilium (GO:0061512)2.74937941
114neural tube formation (GO:0001841)2.74809535
115auditory behavior (GO:0031223)2.71882593
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.70246853
117regulation of cilium movement (GO:0003352)2.66681955
118protein polyglutamylation (GO:0018095)2.59722822
119epithelial cilium movement (GO:0003351)2.59066732
120positive regulation of amino acid transport (GO:0051957)2.57993867
121sialylation (GO:0097503)2.57086662
122positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.56800378
123negative T cell selection (GO:0043383)2.55351956
124positive regulation of gamma-delta T cell activation (GO:0046645)2.51794174
125regulation of mitochondrial fission (GO:0090140)2.46883386
126mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.46588971
127positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.46588971
128positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.42316853
129behavioral response to nicotine (GO:0035095)2.41367579
130iron-sulfur cluster assembly (GO:0016226)2.34599637
131metallo-sulfur cluster assembly (GO:0031163)2.34599637
132negative regulation of telomere maintenance (GO:0032205)2.33025916
133regulation of microtubule-based movement (GO:0060632)2.31613999
134epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.30539777
135positive T cell selection (GO:0043368)2.29971806
136establishment of melanosome localization (GO:0032401)2.29672105
137response to auditory stimulus (GO:0010996)2.29349682
138nonmotile primary cilium assembly (GO:0035058)2.28278437
139interferon-gamma production (GO:0032609)2.28129115
140negative regulation of axon extension (GO:0030517)2.28037580
141synaptic transmission, cholinergic (GO:0007271)2.27309727
142cilium morphogenesis (GO:0060271)2.27008630
143negative thymic T cell selection (GO:0045060)2.26230105
144ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.26052083
145negative regulation of mast cell activation (GO:0033004)2.25749399
146brain morphogenesis (GO:0048854)2.23388231
147heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.22139638
148negative regulation of axonogenesis (GO:0050771)2.19404764
149establishment of pigment granule localization (GO:0051905)2.18638789
150cellular response to leptin stimulus (GO:0044320)2.17020906
151axoneme assembly (GO:0035082)2.16971351
152pyrimidine-containing compound catabolic process (GO:0072529)2.16881646
153retinal ganglion cell axon guidance (GO:0031290)2.16232734
154melanosome transport (GO:0032402)2.15885533
155cilium movement (GO:0003341)2.14715475
156regulation of collateral sprouting (GO:0048670)2.14603045
157melanosome localization (GO:0032400)2.13735877
158glial cell proliferation (GO:0014009)2.11289345
159cellular response to interleukin-15 (GO:0071350)2.10605670
160negative regulation of lymphocyte mediated immunity (GO:0002707)2.10604236
161regulation of vacuole organization (GO:0044088)2.09124415
162regulation of regulatory T cell differentiation (GO:0045589)2.09109649

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.95095855
2GBX2_23144817_ChIP-Seq_PC3_Human3.88139737
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99450266
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.95391399
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.90078260
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.80342416
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.67558505
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.53345607
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.53345607
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.53212918
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.51524912
12REST_21632747_ChIP-Seq_MESCs_Mouse2.46742259
13TAF15_26573619_Chip-Seq_HEK293_Human2.46695917
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.46028729
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.45055975
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.36602707
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.34193727
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.32183603
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.27933227
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26787613
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22432036
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.19446345
23CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18452665
24BMI1_23680149_ChIP-Seq_NPCS_Mouse2.14639001
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.11926048
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.11199565
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.09084224
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.99223673
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94505449
30IGF1R_20145208_ChIP-Seq_DFB_Human1.90673556
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.90009008
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.84701820
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.83144937
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.79049016
35ZNF274_21170338_ChIP-Seq_K562_Hela1.73766057
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73559656
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.72527376
38P300_19829295_ChIP-Seq_ESCs_Human1.69551262
39RNF2_27304074_Chip-Seq_NSC_Mouse1.68445719
40RARB_27405468_Chip-Seq_BRAIN_Mouse1.67923470
41AR_21572438_ChIP-Seq_LNCaP_Human1.65031153
42DROSHA_22980978_ChIP-Seq_HELA_Human1.64451144
43SMAD4_21799915_ChIP-Seq_A2780_Human1.61697273
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52313866
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44129284
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43210636
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42905364
48LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.42393176
49RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41752722
50NR3C1_23031785_ChIP-Seq_PC12_Mouse1.41508922
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40849146
52IRF8_21731497_ChIP-ChIP_J774_Mouse1.39232321
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36196416
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.33898726
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.32704980
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.32275437
57CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.30914269
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.28012908
59AR_25329375_ChIP-Seq_VCAP_Human1.26721732
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.24471928
61FUS_26573619_Chip-Seq_HEK293_Human1.22917779
62VDR_22108803_ChIP-Seq_LS180_Human1.22843625
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.21952493
64IRF8_22096565_ChIP-ChIP_GC-B_Human1.20780090
65ERG_21242973_ChIP-ChIP_JURKAT_Human1.20279554
66HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.19869095
67CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19554634
68ER_23166858_ChIP-Seq_MCF-7_Human1.18887160
69CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17383839
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17128331
71TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16191189
72HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.15937606
73JUN_21703547_ChIP-Seq_K562_Human1.15596203
74RING1B_27294783_Chip-Seq_ESCs_Mouse1.15567978
75RUNX_20019798_ChIP-Seq_JUKART_Human1.15392754
76FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.14654225
77MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.14275838
78MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.10584252
79MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.10011126
80RUNX2_22187159_ChIP-Seq_PCA_Human1.09678361
81ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.07777129
82PRDM14_20953172_ChIP-Seq_ESCs_Human1.07542860
83TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07079788
84CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.06981210
85ELF1_17652178_ChIP-ChIP_JURKAT_Human1.06894471
86TP53_22573176_ChIP-Seq_HFKS_Human1.05996074
87RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05024994
88IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.04799472
89STAT3_23295773_ChIP-Seq_U87_Human1.04733603
90AHR_22903824_ChIP-Seq_MCF-7_Human1.02145752
91CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.00967307
92ARNT_22903824_ChIP-Seq_MCF-7_Human1.00622371
93AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00474729
94RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00305713
95ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99732864
96RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95169689
97SMAD_19615063_ChIP-ChIP_OVARY_Human0.95037695
98SMAD3_21741376_ChIP-Seq_ESCs_Human0.94788601
99P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94230669
100RING1B_27294783_Chip-Seq_NPCs_Mouse0.93063427
101NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92039342
102BCAT_22108803_ChIP-Seq_LS180_Human0.91901414
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91397921
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91397921
105* TCF4_23295773_ChIP-Seq_U87_Human0.91312390
106OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.90756779
107* AR_19668381_ChIP-Seq_PC3_Human0.90484568
108YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90394811
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89819275
110ELK4_26923725_Chip-Seq_MESODERM_Mouse0.89670235
111IRF1_19129219_ChIP-ChIP_H3396_Human0.88340026
112MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88125871
113* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.87812440
114TP53_18474530_ChIP-ChIP_U2OS_Human0.86119265
115FLI1_27457419_Chip-Seq_LIVER_Mouse0.85218632
116TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.85069075
117EWS_26573619_Chip-Seq_HEK293_Human0.84449198
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.84112318
119KDM2B_26808549_Chip-Seq_REH_Human0.84024400
120SOX9_26525672_Chip-Seq_HEART_Mouse0.83731935
121EP300_21415370_ChIP-Seq_HL-1_Mouse0.82556326
122TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.81901329
123DNAJC2_21179169_ChIP-ChIP_NT2_Human0.81832752
124PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.81718003
125CBP_20019798_ChIP-Seq_JUKART_Human0.80855964
126IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.80855964
127CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.80168883
128* TAL1_26923725_Chip-Seq_HPCs_Mouse0.80010904
129PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.79046519
130IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.78785421
131PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77952559
132GATA3_27048872_Chip-Seq_THYMUS_Human0.75635063
133MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.75089473

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.45890623
2MP0004859_abnormal_synaptic_plasticity4.17494695
3MP0006276_abnormal_autonomic_nervous3.36282693
4MP0003635_abnormal_synaptic_transmissio3.29521315
5MP0004270_analgesia2.99558526
6MP0001968_abnormal_touch/_nociception2.96753616
7MP0003122_maternal_imprinting2.90815262
8MP0009745_abnormal_behavioral_response2.84853449
9MP0005423_abnormal_somatic_nervous2.79500171
10MP0002063_abnormal_learning/memory/cond2.75000603
11MP0002064_seizures2.68616036
12MP0001529_abnormal_vocalization2.67639259
13MP0002734_abnormal_mechanical_nocicepti2.65846303
14MP0002735_abnormal_chemical_nociception2.61163080
15MP0002736_abnormal_nociception_after2.59838919
16MP0009046_muscle_twitch2.54174151
17MP0002572_abnormal_emotion/affect_behav2.53655356
18MP0003724_increased_susceptibility_to2.47554686
19MP0002822_catalepsy2.33779123
20MP0005645_abnormal_hypothalamus_physiol2.27643229
21MP0000778_abnormal_nervous_system2.24584848
22MP0002272_abnormal_nervous_system2.24159286
23MP0001440_abnormal_grooming_behavior2.23855399
24MP0001905_abnormal_dopamine_level2.22947162
25MP0001984_abnormal_olfaction2.18491365
26MP0002733_abnormal_thermal_nociception2.17550498
27MP0002184_abnormal_innervation2.13414371
28MP0001970_abnormal_pain_threshold2.09157069
29MP0004858_abnormal_nervous_system2.00239473
30MP0001486_abnormal_startle_reflex1.99001421
31MP0000372_irregular_coat_pigmentation1.98147290
32MP0002067_abnormal_sensory_capabilities1.85612699
33MP0001501_abnormal_sleep_pattern1.82249343
34MP0005671_abnormal_response_to1.81774638
35MP0003787_abnormal_imprinting1.79507919
36MP0002557_abnormal_social/conspecific_i1.79475369
37MP0005386_behavior/neurological_phenoty1.74672627
38MP0004924_abnormal_behavior1.74672627
39MP0005075_abnormal_melanosome_morpholog1.67453770
40MP0005646_abnormal_pituitary_gland1.61941725
41MP0004811_abnormal_neuron_physiology1.59777108
42MP0000955_abnormal_spinal_cord1.49369883
43MP0000015_abnormal_ear_pigmentation1.47910544
44MP0010386_abnormal_urinary_bladder1.47000597
45MP0002882_abnormal_neuron_morphology1.45694726
46MP0002837_dystrophic_cardiac_calcinosis1.44945318
47MP0001188_hyperpigmentation1.43854455
48MP0000751_myopathy1.43101245
49MP0003011_delayed_dark_adaptation1.40318542
50MP0005394_taste/olfaction_phenotype1.40291516
51MP0005499_abnormal_olfactory_system1.40291516
52MP0004142_abnormal_muscle_tone1.39362615
53MP0003121_genomic_imprinting1.32806573
54MP0003136_yellow_coat_color1.31563205
55MP0002638_abnormal_pupillary_reflex1.31311224
56MP0000465_gastrointestinal_hemorrhage1.29003291
57MP0002066_abnormal_motor_capabilities/c1.28103062
58MP0002909_abnormal_adrenal_gland1.22483280
59MP0003329_amyloid_beta_deposits1.21764587
60MP0005253_abnormal_eye_physiology1.18358561
61MP0008569_lethality_at_weaning1.16834197
62MP0001502_abnormal_circadian_rhythm1.16680911
63MP0008789_abnormal_olfactory_epithelium1.16419980
64MP0000631_abnormal_neuroendocrine_gland1.16375450
65MP0002751_abnormal_autonomic_nervous1.15715055
66MP0005084_abnormal_gallbladder_morpholo1.13993803
67MP0002152_abnormal_brain_morphology1.13444253
68MP0008260_abnormal_autophagy1.09074698
69MP0002095_abnormal_skin_pigmentation1.07676934
70MP0004742_abnormal_vestibular_system1.01326513
71MP0002752_abnormal_somatic_nervous1.00880327
72MP0003879_abnormal_hair_cell0.98684107
73MP0002928_abnormal_bile_duct0.97469448
74MP0001986_abnormal_taste_sensitivity0.97151556
75MP0005174_abnormal_tail_pigmentation0.96804398
76MP0008995_early_reproductive_senescence0.93598273
77MP0002277_abnormal_respiratory_mucosa0.92134661
78MP0002069_abnormal_eating/drinking_beha0.91682009
79MP0002102_abnormal_ear_morphology0.88863332
80MP0009780_abnormal_chondrocyte_physiolo0.88346634
81MP0009785_altered_susceptibility_to0.87831111
82MP0001324_abnormal_eye_pigmentation0.86481499
83MP0000604_amyloidosis0.85513235
84MP0003634_abnormal_glial_cell0.84753759
85MP0002229_neurodegeneration0.84325672
86MP0003866_abnormal_defecation0.83549066
87MP0006082_CNS_inflammation0.82892907
88MP0002653_abnormal_ependyma_morphology0.82624395
89MP0002163_abnormal_gland_morphology0.82483356
90MP0008872_abnormal_physiological_respon0.81707799
91MP0004085_abnormal_heartbeat0.81192059
92MP0005464_abnormal_platelet_physiology0.80979707
93MP0001963_abnormal_hearing_physiology0.80580734
94MP0000538_abnormal_urinary_bladder0.80229927
95MP0003690_abnormal_glial_cell0.79713210
96MP0001835_abnormal_antigen_presentation0.79711177
97MP0002876_abnormal_thyroid_physiology0.79469235
98MP0001299_abnormal_eye_distance/0.79308271
99MP0003631_nervous_system_phenotype0.79070079
100MP0006054_spinal_hemorrhage0.78902112
101MP0001542_abnormal_bone_strength0.78653019
102MP0000013_abnormal_adipose_tissue0.78426062
103MP0005551_abnormal_eye_electrophysiolog0.78365047
104MP0001664_abnormal_digestion0.77093235
105MP0005025_abnormal_response_to0.75680340
106MP0004381_abnormal_hair_follicle0.75563740
107MP0002723_abnormal_immune_serum0.75519854
108MP0003436_decreased_susceptibility_to0.74795870
109MP0005000_abnormal_immune_tolerance0.74654547
110MP0003633_abnormal_nervous_system0.74485937
111MP0003861_abnormal_nervous_system0.73547876
112MP0006072_abnormal_retinal_apoptosis0.72340298
113MP0000026_abnormal_inner_ear0.72249166
114MP0008877_abnormal_DNA_methylation0.72014607
115MP0002420_abnormal_adaptive_immunity0.70809158
116MP0004885_abnormal_endolymph0.70740282
117MP0001943_abnormal_respiration0.70660178
118MP0001177_atelectasis0.70443342
119MP0001800_abnormal_humoral_immune0.69993518
120MP0000569_abnormal_digit_pigmentation0.67306536
121MP0003646_muscle_fatigue0.67032454
122MP0003632_abnormal_nervous_system0.66992051
123MP0000534_abnormal_ureter_morphology0.66384471
124MP0003123_paternal_imprinting0.62821820
125MP0005535_abnormal_body_temperature0.60100205
126MP0005623_abnormal_meninges_morphology0.58576038
127MP0003137_abnormal_impulse_conducting0.57971961
128MP0003942_abnormal_urinary_system0.57821369
129MP0005409_darkened_coat_color0.57380836
130MP0002332_abnormal_exercise_endurance0.57045532
131MP0004133_heterotaxia0.56159515
132MP0005171_absent_coat_pigmentation0.55547013
133MP0004145_abnormal_muscle_electrophysio0.55094593
134MP0004215_abnormal_myocardial_fiber0.53994124

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.32260752
2Myokymia (HP:0002411)5.20614578
3Limb dystonia (HP:0002451)4.98176758
4Atonic seizures (HP:0010819)4.34486387
5Focal seizures (HP:0007359)4.24172463
6Visual hallucinations (HP:0002367)3.93608488
7Pheochromocytoma (HP:0002666)3.85249275
8Hypothermia (HP:0002045)3.75054152
9Febrile seizures (HP:0002373)3.73019779
10Failure to thrive in infancy (HP:0001531)3.61026687
11Epileptic encephalopathy (HP:0200134)3.56893019
12Neuroendocrine neoplasm (HP:0100634)3.54819397
13Polyphagia (HP:0002591)3.54756380
14Progressive cerebellar ataxia (HP:0002073)3.48853888
15Amyotrophic lateral sclerosis (HP:0007354)3.46887070
16Absence seizures (HP:0002121)3.45177604
17Abnormal hair whorl (HP:0010721)3.36324987
18Acute necrotizing encephalopathy (HP:0006965)3.16973155
19True hermaphroditism (HP:0010459)3.13373403
20Gait imbalance (HP:0002141)3.07995005
21Abnormality of midbrain morphology (HP:0002418)3.03430508
22Molar tooth sign on MRI (HP:0002419)3.03430508
23Dialeptic seizures (HP:0011146)3.02940877
24Ankle clonus (HP:0011448)3.02512959
25Stomatitis (HP:0010280)3.00522984
26Pancreatic cysts (HP:0001737)2.96936658
27Generalized tonic-clonic seizures (HP:0002069)2.92869628
28Abnormal mitochondria in muscle tissue (HP:0008316)2.92714903
29Abnormal eating behavior (HP:0100738)2.88297461
30Progressive inability to walk (HP:0002505)2.88150442
31Progressive macrocephaly (HP:0004481)2.87850543
32Amblyopia (HP:0000646)2.86792222
33Pancreatic fibrosis (HP:0100732)2.83447151
34Hypoventilation (HP:0002791)2.82352698
35Poor suck (HP:0002033)2.77306553
36Nephronophthisis (HP:0000090)2.74458689
37Supranuclear gaze palsy (HP:0000605)2.63818436
38Medial flaring of the eyebrow (HP:0010747)2.63616174
39Hypoplasia of the brainstem (HP:0002365)2.60945976
40Aplasia/Hypoplasia of the brainstem (HP:0007362)2.60945976
41Severe combined immunodeficiency (HP:0004430)2.60549931
42Congenital primary aphakia (HP:0007707)2.57396973
43Split foot (HP:0001839)2.56447820
44Absent speech (HP:0001344)2.55501300
45Hemiplegia (HP:0002301)2.52451373
46Abnormality of the corticospinal tract (HP:0002492)2.51729807
47Abnormality of the labia minora (HP:0012880)2.51682816
48Abnormality of glycolysis (HP:0004366)2.51046763
49Increased serum pyruvate (HP:0003542)2.51046763
50Mitochondrial inheritance (HP:0001427)2.49326806
51Genital tract atresia (HP:0001827)2.48618692
52Atrophy/Degeneration involving motor neurons (HP:0007373)2.47423098
53Mutism (HP:0002300)2.47158395
54Specific learning disability (HP:0001328)2.47109107
55Pachygyria (HP:0001302)2.46997071
56Hyperventilation (HP:0002883)2.46707703
57Elevated erythrocyte sedimentation rate (HP:0003565)2.46250931
58Nephrogenic diabetes insipidus (HP:0009806)2.46043538
59Vaginal atresia (HP:0000148)2.45961980
60Broad-based gait (HP:0002136)2.42688691
61Anxiety (HP:0000739)2.41963560
62Esotropia (HP:0000565)2.40801537
633-Methylglutaconic aciduria (HP:0003535)2.39832868
64Peripheral hypomyelination (HP:0007182)2.30428810
65Oligomenorrhea (HP:0000876)2.29132198
66Truncal ataxia (HP:0002078)2.28110281
67Fetal akinesia sequence (HP:0001989)2.25584122
68Agitation (HP:0000713)2.24223280
69Impaired vibration sensation in the lower limbs (HP:0002166)2.23795934
70Heterochromia iridis (HP:0001100)2.23279352
71Insidious onset (HP:0003587)2.22369872
72Termporal pattern (HP:0011008)2.22369872
73Abnormality of pain sensation (HP:0010832)2.20699455
74Impaired pain sensation (HP:0007328)2.20699455
75Acute encephalopathy (HP:0006846)2.20333719
76Abnormality of the renal medulla (HP:0100957)2.19941603
77T lymphocytopenia (HP:0005403)2.19584920
78Narrow nasal bridge (HP:0000446)2.19129380
79Thyroiditis (HP:0100646)2.17980595
80Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.16546464
81Degeneration of the lateral corticospinal tracts (HP:0002314)2.16546464
82Lissencephaly (HP:0001339)2.15746068
83Epileptiform EEG discharges (HP:0011182)2.14310113
84Action tremor (HP:0002345)2.13395581
85Drooling (HP:0002307)2.12420510
86Excessive salivation (HP:0003781)2.12420510
87Depression (HP:0000716)2.12123282
88EEG with generalized epileptiform discharges (HP:0011198)2.10176375
89Abnormality of eosinophils (HP:0001879)2.09726920
90Urinary urgency (HP:0000012)2.09573995
91Abnormal respiratory motile cilium morphology (HP:0005938)2.07642155
92Abnormal respiratory epithelium morphology (HP:0012253)2.07642155
93Neoplasm of the peripheral nervous system (HP:0100007)2.07475114
94Generalized hypotonia (HP:0001290)2.06069399
95Myositis (HP:0100614)2.03236795
96Urinary bladder sphincter dysfunction (HP:0002839)2.02826069
97Hypsarrhythmia (HP:0002521)2.01388799
98Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.00467701
99Akinesia (HP:0002304)2.00009415
100Hyperthyroidism (HP:0000836)1.98957788
101Spastic gait (HP:0002064)1.98750920
102Sleep apnea (HP:0010535)1.98221034
103Postaxial hand polydactyly (HP:0001162)1.97731525
104Increased CSF lactate (HP:0002490)1.94949077
105Lower limb muscle weakness (HP:0007340)1.93458817
106Hepatocellular necrosis (HP:0001404)1.93183752
107Abnormal ciliary motility (HP:0012262)1.92867506
108Torticollis (HP:0000473)1.92803829
109Congenital stationary night blindness (HP:0007642)1.92330105
110Exotropia (HP:0000577)1.92034456
111Retrobulbar optic neuritis (HP:0100654)1.90791246
112Optic neuritis (HP:0100653)1.90791246
113Inability to walk (HP:0002540)1.89183834
114Ulnar claw (HP:0001178)1.88323772
115Delayed gross motor development (HP:0002194)1.87738900
116Renal cortical cysts (HP:0000803)1.87595375
117Abnormal respiratory motile cilium physiology (HP:0012261)1.86023192
118Abnormality of T cell number (HP:0011839)1.85550893
119Delusions (HP:0000746)1.84815646
120Shoulder girdle muscle weakness (HP:0003547)1.84052117
121Diplopia (HP:0000651)1.84016117
122Abnormality of binocular vision (HP:0011514)1.84016117
123Papilledema (HP:0001085)1.82983733
124Cerebral inclusion bodies (HP:0100314)1.82906718
125Focal dystonia (HP:0004373)1.82649346
126Optic disc pallor (HP:0000543)1.81772002
127Aplasia/Hypoplasia of the lens (HP:0008063)1.80845586
128Psychosis (HP:0000709)1.80610353
129Myotonia (HP:0002486)1.78299663
130Morphological abnormality of the pyramidal tract (HP:0002062)1.77943686
131Hepatic necrosis (HP:0002605)1.77832171
132Hemiparesis (HP:0001269)1.77803997
133Abnormality of the vocal cords (HP:0008777)1.77340385
134Spastic tetraplegia (HP:0002510)1.76802650
135Retinal dysplasia (HP:0007973)1.76712208
136Leukocytosis (HP:0001974)1.76572861
137Broad foot (HP:0001769)1.76201088
138Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.75161639
139Nasal speech (HP:0001611)1.74809797
140Poor coordination (HP:0002370)1.74369922
141Abnormality of the renal cortex (HP:0011035)1.74139876
142Abnormality of the fovea (HP:0000493)1.73865962
143Panhypogammaglobulinemia (HP:0003139)1.71878736
144Narrow forehead (HP:0000341)1.71567349
145Palpebral edema (HP:0100540)1.70509866
146IgG deficiency (HP:0004315)1.69290626
147Iris hypopigmentation (HP:0007730)1.69247807
148Postaxial foot polydactyly (HP:0001830)1.68818698
149Anencephaly (HP:0002323)1.68483715
150Generalized hypopigmentation (HP:0007513)1.67964372

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.23126810
2CASK3.83964048
3MAP3K123.59415806
4NTRK33.31689136
5MAP3K43.09118190
6MAP2K72.94732743
7MAP4K22.76296075
8MINK12.67929582
9MAP3K92.55073851
10MAPK132.48167907
11NTRK22.28707288
12TXK2.06351317
13LIMK11.93276305
14EPHA31.91936572
15ARAF1.90050789
16PLK21.88804687
17GRK51.84740395
18TESK21.83921412
19MAP2K41.73263154
20SIK31.72668636
21BCKDK1.70340503
22DYRK21.65094290
23UHMK11.54042014
24TAOK31.52822374
25BCR1.51849965
26GRK71.50602707
27EPHA41.47518253
28PNCK1.47208896
29PAK61.44134456
30ERBB31.42999830
31TRIM281.41195090
32PINK11.38667277
33NTRK11.37837298
34DAPK21.33531875
35KSR11.32257500
36TNIK1.31230689
37PHKG11.30404608
38PHKG21.30404608
39GRK61.30258156
40MAP4K11.29959617
41CDK51.26950257
42LATS21.24043629
43CSNK1G21.17044616
44PRPF4B1.15188123
45CSNK1G31.13094514
46DYRK1B1.11910598
47CAMK2A1.10987993
48KDR1.10368757
49MAP3K111.10048236
50DAPK11.08740381
51NME11.07639238
52CDK181.06723064
53SGK2231.06337096
54SGK4941.06337096
55KSR21.05179540
56CDK141.04414734
57PRKCG1.02211324
58MAPK151.01543712
59CAMK2B1.00033808
60MAPKAPK50.99418161
61ADRBK20.97905281
62CDK150.96629396
63PAK30.95757033
64TNK20.94174889
65SIK20.93302618
66SYK0.93222911
67CDK190.91872621
68ADRBK10.91598400
69EPHB10.88271266
70MYLK0.86187274
71CSK0.84454433
72WNK30.84295549
73CDK11A0.84282618
74ITK0.84123340
75BMPR1B0.83453832
76TAOK10.82251657
77MAP3K50.81117592
78BLK0.78356925
79DYRK1A0.77959052
80PRKCE0.77623272
81BRAF0.77412587
82HCK0.77262027
83RPS6KA20.76062120
84IKBKE0.74325467
85SGK20.74183579
86PTK2B0.74016410
87LYN0.73983280
88FES0.72758318
89PRKD20.72743895
90RIPK40.72743190
91LCK0.72232919
92TSSK60.72080062
93OXSR10.70554618
94ZAP700.69985763
95FRK0.69006824
96BTK0.68789004
97FER0.68033120
98ROCK20.67612329
99FYN0.65685816
100CAMK2D0.64274119
101CAMKK20.63331418
102KIT0.62728266
103CSNK1G10.62703042
104CSF1R0.62589761
105RPS6KA40.60304222
106LMTK20.59698774
107FGFR20.59657328
108AKT30.59512053
109BMPR20.58292007
110MAP2K10.57346720
111ROCK10.57181453
112FGR0.56785068
113RET0.55971303
114CAMK2G0.55578105
115TESK10.54693205
116ERBB40.54413369
117PIM20.54256264
118TYK20.53472507
119CSNK1A1L0.53168202
120TYRO30.52729693
121PRKD10.52223422
122EPHB20.51729751
123PRKCQ0.50812025
124PRKD30.50379271
125TEC0.50110272
126MUSK0.49432839
127CAMKK10.47928506
128MARK20.47820751
129PKN10.44610621
130PRKCZ0.44469980
131TBK10.43615727
132DYRK30.43572785
133CAMK10.41445275
134MAPK120.41340984
135STK390.41332216
136GRK10.40803344
137RAF10.40296275
138PRKCH0.39713062
139PLK30.39187168
140PRKACA0.38626612
141MAP3K20.36997032
142STK380.36619062
143MAP3K60.36491393
144DAPK30.35454978
145WNK40.32283354

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.76629000
2Nicotine addiction_Homo sapiens_hsa050333.64538432
3Collecting duct acid secretion_Homo sapiens_hsa049662.98893006
4Oxidative phosphorylation_Homo sapiens_hsa001902.90103646
5Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.51787175
6GABAergic synapse_Homo sapiens_hsa047272.49647368
7Parkinsons disease_Homo sapiens_hsa050122.46596172
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.46187130
9Olfactory transduction_Homo sapiens_hsa047402.38716013
10Primary immunodeficiency_Homo sapiens_hsa053402.28289836
11Dopaminergic synapse_Homo sapiens_hsa047282.18330070
12Vibrio cholerae infection_Homo sapiens_hsa051102.16155400
13Morphine addiction_Homo sapiens_hsa050322.14726285
14Circadian entrainment_Homo sapiens_hsa047132.09233402
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.05414680
16Serotonergic synapse_Homo sapiens_hsa047262.02034643
17Amphetamine addiction_Homo sapiens_hsa050311.95886077
18Alzheimers disease_Homo sapiens_hsa050101.94768023
19Glutamatergic synapse_Homo sapiens_hsa047241.93146259
20Cocaine addiction_Homo sapiens_hsa050301.92311702
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.89574864
22Taste transduction_Homo sapiens_hsa047421.85677982
23Long-term potentiation_Homo sapiens_hsa047201.75934976
24Cholinergic synapse_Homo sapiens_hsa047251.72664149
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.70477624
26Huntingtons disease_Homo sapiens_hsa050161.70159599
27Cardiac muscle contraction_Homo sapiens_hsa042601.66118631
28Insulin secretion_Homo sapiens_hsa049111.55385602
29Long-term depression_Homo sapiens_hsa047301.54042151
30Axon guidance_Homo sapiens_hsa043601.46756673
31Salivary secretion_Homo sapiens_hsa049701.37931565
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37536057
33Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.36376409
34Renin secretion_Homo sapiens_hsa049241.32037177
35Gap junction_Homo sapiens_hsa045401.31890268
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.27606489
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27251678
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.23653577
39Gastric acid secretion_Homo sapiens_hsa049711.23404214
40Graft-versus-host disease_Homo sapiens_hsa053321.19289136
41Oxytocin signaling pathway_Homo sapiens_hsa049211.15711969
42Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.14467836
43Calcium signaling pathway_Homo sapiens_hsa040201.13863126
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12816087
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.11206337
46Salmonella infection_Homo sapiens_hsa051321.10867912
47GnRH signaling pathway_Homo sapiens_hsa049121.10041937
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.05005772
49Protein export_Homo sapiens_hsa030601.02444143
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01674615
51Phagosome_Homo sapiens_hsa041451.00235213
52Autoimmune thyroid disease_Homo sapiens_hsa053200.99104635
53Allograft rejection_Homo sapiens_hsa053300.98892586
54Rheumatoid arthritis_Homo sapiens_hsa053230.97497223
55Shigellosis_Homo sapiens_hsa051310.96907374
56Phototransduction_Homo sapiens_hsa047440.96672669
57T cell receptor signaling pathway_Homo sapiens_hsa046600.94539743
58Hematopoietic cell lineage_Homo sapiens_hsa046400.93282735
59Chemokine signaling pathway_Homo sapiens_hsa040620.89208401
60Melanogenesis_Homo sapiens_hsa049160.85496792
61Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.85267527
62ErbB signaling pathway_Homo sapiens_hsa040120.84987522
63Osteoclast differentiation_Homo sapiens_hsa043800.84446676
64Antigen processing and presentation_Homo sapiens_hsa046120.83845246
65Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82145661
66Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.81420205
67Estrogen signaling pathway_Homo sapiens_hsa049150.80500724
68Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.77569128
69cAMP signaling pathway_Homo sapiens_hsa040240.75206350
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75008255
71Alcoholism_Homo sapiens_hsa050340.72658156
72Dilated cardiomyopathy_Homo sapiens_hsa054140.70734313
73Fatty acid elongation_Homo sapiens_hsa000620.69138960
74Tuberculosis_Homo sapiens_hsa051520.68116580
75Oocyte meiosis_Homo sapiens_hsa041140.68011088
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67832697
77Glioma_Homo sapiens_hsa052140.67577619
78Intestinal immune network for IgA production_Homo sapiens_hsa046720.66395161
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.65470547
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64934268
81Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64320028
82Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.63442762
83Steroid biosynthesis_Homo sapiens_hsa001000.62993423
84Lysosome_Homo sapiens_hsa041420.62946309
85Glycosaminoglycan degradation_Homo sapiens_hsa005310.62895553
86RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.62874225
87Type I diabetes mellitus_Homo sapiens_hsa049400.62527513
88Type II diabetes mellitus_Homo sapiens_hsa049300.61703488
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60830586
90Viral myocarditis_Homo sapiens_hsa054160.60066857
91Peroxisome_Homo sapiens_hsa041460.59991394
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59445309
93Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.59258280
94Pertussis_Homo sapiens_hsa051330.58681024
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58366106
96Proteasome_Homo sapiens_hsa030500.56721182
97Platelet activation_Homo sapiens_hsa046110.55714121
98Malaria_Homo sapiens_hsa051440.54808177
99Ras signaling pathway_Homo sapiens_hsa040140.54407284
100MAPK signaling pathway_Homo sapiens_hsa040100.54265062
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53403722
102Renal cell carcinoma_Homo sapiens_hsa052110.51735944
103Leishmaniasis_Homo sapiens_hsa051400.51686800
104Staphylococcus aureus infection_Homo sapiens_hsa051500.50474769
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49812501
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48709817
107Endometrial cancer_Homo sapiens_hsa052130.48480706
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48478467
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.47147118
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47110988
111Colorectal cancer_Homo sapiens_hsa052100.46897607
112Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46216284
113Thyroid hormone synthesis_Homo sapiens_hsa049180.45399179
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44400198
115Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43899019
116Asthma_Homo sapiens_hsa053100.43690268
117Nitrogen metabolism_Homo sapiens_hsa009100.42542136
118Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40037382
119Endocytosis_Homo sapiens_hsa041440.39867261
120Prion diseases_Homo sapiens_hsa050200.38450355
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37679217
122Wnt signaling pathway_Homo sapiens_hsa043100.37491967
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.37472873
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36866707
125Hedgehog signaling pathway_Homo sapiens_hsa043400.36598055
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.36385842
127Dorso-ventral axis formation_Homo sapiens_hsa043200.34950411
128Regulation of autophagy_Homo sapiens_hsa041400.34070222
129Ovarian steroidogenesis_Homo sapiens_hsa049130.33711997
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33539695
131Melanoma_Homo sapiens_hsa052180.32805335
132Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32472537
133Choline metabolism in cancer_Homo sapiens_hsa052310.32301200
134Rap1 signaling pathway_Homo sapiens_hsa040150.31008569
135Butanoate metabolism_Homo sapiens_hsa006500.30659340
136Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.29808101
137Pancreatic secretion_Homo sapiens_hsa049720.29444710
138Insulin signaling pathway_Homo sapiens_hsa049100.28750249
139Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.28693844
140Tight junction_Homo sapiens_hsa045300.26721416
141Ether lipid metabolism_Homo sapiens_hsa005650.25911265
142Glucagon signaling pathway_Homo sapiens_hsa049220.24635510

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »