Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.54443037 |
2 | L-phenylalanine catabolic process (GO:0006559) | 7.54443037 |
3 | L-phenylalanine metabolic process (GO:0006558) | 7.17723064 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.17723064 |
5 | extracellular fibril organization (GO:0043206) | 7.15881169 |
6 | aromatic amino acid family catabolic process (GO:0009074) | 6.88386191 |
7 | glyoxylate metabolic process (GO:0046487) | 6.61946140 |
8 | collagen fibril organization (GO:0030199) | 6.50085108 |
9 | tryptophan catabolic process (GO:0006569) | 6.33769559 |
10 | indole-containing compound catabolic process (GO:0042436) | 6.33769559 |
11 | indolalkylamine catabolic process (GO:0046218) | 6.33769559 |
12 | kynurenine metabolic process (GO:0070189) | 6.17542458 |
13 | fibril organization (GO:0097435) | 6.00666139 |
14 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.99851360 |
15 | tryptophan metabolic process (GO:0006568) | 5.92129174 |
16 | bile acid biosynthetic process (GO:0006699) | 5.82641439 |
17 | cysteine metabolic process (GO:0006534) | 5.59262484 |
18 | negative regulation of fibrinolysis (GO:0051918) | 5.43345810 |
19 | high-density lipoprotein particle remodeling (GO:0034375) | 5.41778529 |
20 | regulation of fibrinolysis (GO:0051917) | 5.30976188 |
21 | alpha-linolenic acid metabolic process (GO:0036109) | 5.29647530 |
22 | protein carboxylation (GO:0018214) | 5.24612346 |
23 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.24612346 |
24 | serine family amino acid catabolic process (GO:0009071) | 5.23417733 |
25 | response to follicle-stimulating hormone (GO:0032354) | 5.19962146 |
26 | lysine catabolic process (GO:0006554) | 5.13715592 |
27 | lysine metabolic process (GO:0006553) | 5.13715592 |
28 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 5.13390078 |
29 | urea cycle (GO:0000050) | 5.09910778 |
30 | urea metabolic process (GO:0019627) | 5.09910778 |
31 | sulfur amino acid catabolic process (GO:0000098) | 5.06224488 |
32 | regulation of protein activation cascade (GO:2000257) | 5.03183535 |
33 | complement activation, alternative pathway (GO:0006957) | 4.98849785 |
34 | cellular ketone body metabolic process (GO:0046950) | 4.98390363 |
35 | aromatic amino acid family metabolic process (GO:0009072) | 4.97734060 |
36 | growth hormone secretion (GO:0030252) | 4.89885806 |
37 | bile acid metabolic process (GO:0008206) | 4.88381599 |
38 | amino-acid betaine metabolic process (GO:0006577) | 4.86538362 |
39 | urate metabolic process (GO:0046415) | 4.82893244 |
40 | reverse cholesterol transport (GO:0043691) | 4.79314510 |
41 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 4.79192581 |
42 | regulation of cholesterol esterification (GO:0010872) | 4.77869781 |
43 | positive regulation of Rho protein signal transduction (GO:0035025) | 4.75805699 |
44 | nitrogen cycle metabolic process (GO:0071941) | 4.72374196 |
45 | homocysteine metabolic process (GO:0050667) | 4.69606002 |
46 | regulation of complement activation (GO:0030449) | 4.69108810 |
47 | alpha-amino acid catabolic process (GO:1901606) | 4.61669254 |
48 | tyrosine metabolic process (GO:0006570) | 4.61307555 |
49 | protein-lipid complex remodeling (GO:0034368) | 4.61171977 |
50 | macromolecular complex remodeling (GO:0034367) | 4.61171977 |
51 | plasma lipoprotein particle remodeling (GO:0034369) | 4.61171977 |
52 | acylglycerol homeostasis (GO:0055090) | 4.50923462 |
53 | triglyceride homeostasis (GO:0070328) | 4.50923462 |
54 | drug transmembrane transport (GO:0006855) | 4.48522010 |
55 | indolalkylamine metabolic process (GO:0006586) | 4.47692529 |
56 | cell migration involved in heart development (GO:0060973) | 4.46756269 |
57 | glomerular visceral epithelial cell development (GO:0072015) | 4.41290082 |
58 | glutamate metabolic process (GO:0006536) | 4.39018640 |
59 | regulation of triglyceride catabolic process (GO:0010896) | 4.35479607 |
60 | phospholipid efflux (GO:0033700) | 4.34057414 |
61 | coenzyme catabolic process (GO:0009109) | 4.33417845 |
62 | glycine metabolic process (GO:0006544) | 4.32864016 |
63 | serine family amino acid metabolic process (GO:0009069) | 4.32200687 |
64 | amine catabolic process (GO:0009310) | 4.30695523 |
65 | cellular biogenic amine catabolic process (GO:0042402) | 4.30695523 |
66 | cellular amino acid catabolic process (GO:0009063) | 4.30560269 |
67 | ketone body metabolic process (GO:1902224) | 4.30483645 |
68 | cellular modified amino acid catabolic process (GO:0042219) | 4.26284639 |
69 | negative regulation of sterol transport (GO:0032372) | 4.25607866 |
70 | negative regulation of cholesterol transport (GO:0032375) | 4.25607866 |
71 | cellular zinc ion homeostasis (GO:0006882) | 4.14434521 |
72 | aldehyde catabolic process (GO:0046185) | 4.13934029 |
73 | plasma lipoprotein particle clearance (GO:0034381) | 4.13534398 |
74 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.12762786 |
75 | keratan sulfate catabolic process (GO:0042340) | 4.11859064 |
76 | benzene-containing compound metabolic process (GO:0042537) | 4.11135714 |
77 | drug catabolic process (GO:0042737) | 4.10868298 |
78 | serine family amino acid biosynthetic process (GO:0009070) | 4.07595124 |
79 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 4.05812954 |
80 | bile acid and bile salt transport (GO:0015721) | 4.03049462 |
81 | cholesterol efflux (GO:0033344) | 4.01562945 |
82 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.97278456 |
83 | regulation of cardiac muscle hypertrophy (GO:0010611) | 3.96487509 |
84 | cellular glucuronidation (GO:0052695) | 3.94898543 |
85 | cell adhesion mediated by integrin (GO:0033627) | 3.94355264 |
86 | short-chain fatty acid metabolic process (GO:0046459) | 3.94149577 |
87 | glomerular epithelial cell development (GO:0072310) | 3.93454239 |
88 | fibrinolysis (GO:0042730) | 3.93409015 |
89 | dopamine transport (GO:0015872) | 3.92037376 |
90 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 3.91699070 |
91 | positive regulation of growth hormone secretion (GO:0060124) | 3.86256881 |
92 | imidazole-containing compound metabolic process (GO:0052803) | 3.82588942 |
93 | organic acid catabolic process (GO:0016054) | 3.82128884 |
94 | carboxylic acid catabolic process (GO:0046395) | 3.82128884 |
95 | regulation of muscle hypertrophy (GO:0014743) | 3.79943704 |
96 | aspartate family amino acid catabolic process (GO:0009068) | 3.78912076 |
97 | blood coagulation, intrinsic pathway (GO:0007597) | 3.77803433 |
98 | 2-oxoglutarate metabolic process (GO:0006103) | 3.75693813 |
99 | plasma lipoprotein particle assembly (GO:0034377) | 3.75434398 |
100 | arginine metabolic process (GO:0006525) | 3.75169700 |
101 | low-density lipoprotein particle remodeling (GO:0034374) | 3.74472853 |
102 | collagen metabolic process (GO:0032963) | 3.73253076 |
103 | phospholipid homeostasis (GO:0055091) | 3.72349543 |
104 | drug transport (GO:0015893) | 3.72249373 |
105 | acetyl-CoA metabolic process (GO:0006084) | 3.71265748 |
106 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.71246182 |
107 | exogenous drug catabolic process (GO:0042738) | 3.70597457 |
108 | lymphangiogenesis (GO:0001946) | 3.69630363 |
109 | ethanol oxidation (GO:0006069) | 3.69254476 |
110 | carnitine metabolic process (GO:0009437) | 3.69247745 |
111 | fatty acid oxidation (GO:0019395) | 3.66613236 |
112 | sperm motility (GO:0030317) | 3.65355411 |
113 | fatty acid beta-oxidation (GO:0006635) | 3.64458635 |
114 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.64260396 |
115 | chondrocyte development (GO:0002063) | 3.63819960 |
116 | monocarboxylic acid catabolic process (GO:0072329) | 3.62788734 |
117 | glucuronate metabolic process (GO:0019585) | 3.60693917 |
118 | uronic acid metabolic process (GO:0006063) | 3.60693917 |
119 | regulation of cholesterol homeostasis (GO:2000188) | 3.60496144 |
120 | lipid oxidation (GO:0034440) | 3.59434936 |
121 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.57869777 |
122 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.57869777 |
123 | cholesterol homeostasis (GO:0042632) | 3.57060987 |
124 | multicellular organismal macromolecule metabolic process (GO:0044259) | 3.56908179 |
125 | cofactor catabolic process (GO:0051187) | 3.56575720 |
126 | catechol-containing compound biosynthetic process (GO:0009713) | 3.54794896 |
127 | catecholamine biosynthetic process (GO:0042423) | 3.54794896 |
128 | multicellular organismal metabolic process (GO:0044236) | 3.53568625 |
129 | cytolysis (GO:0019835) | 3.53471902 |
130 | sterol homeostasis (GO:0055092) | 3.52695788 |
131 | collagen catabolic process (GO:0030574) | 3.50849035 |
132 | astrocyte development (GO:0014002) | 3.48252250 |
133 | basement membrane organization (GO:0071711) | 3.46403457 |
134 | interleukin-1-mediated signaling pathway (GO:0070498) | 3.46337391 |
135 | cartilage morphogenesis (GO:0060536) | 3.39515176 |
136 | seminiferous tubule development (GO:0072520) | 3.38796049 |
137 | desmosome organization (GO:0002934) | 3.35812244 |
138 | endocardial cushion development (GO:0003197) | 3.33992460 |
139 | glycoprotein catabolic process (GO:0006516) | 3.33852554 |
140 | multicellular organismal catabolic process (GO:0044243) | 3.33503380 |
141 | ovulation from ovarian follicle (GO:0001542) | 3.30545535 |
142 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 3.28004746 |
143 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.27968226 |
144 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 3.22975188 |
145 | organic cation transport (GO:0015695) | 3.21729061 |
146 | cardiac epithelial to mesenchymal transition (GO:0060317) | 3.21263695 |
147 | regulation of cardiac muscle cell differentiation (GO:2000725) | 3.18982384 |
148 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.15269753 |
149 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.14834054 |
150 | protein targeting to Golgi (GO:0000042) | 3.14147494 |
151 | response to prostaglandin E (GO:0034695) | 3.13493668 |
152 | cardiac chamber formation (GO:0003207) | 3.13180394 |
153 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 3.12595393 |
154 | apoptotic cell clearance (GO:0043277) | 3.12135119 |
155 | protein retention in ER lumen (GO:0006621) | 3.08113367 |
156 | regulation of dopamine secretion (GO:0014059) | 3.06232502 |
157 | skin development (GO:0043588) | 3.01593739 |
158 | glial cell migration (GO:0008347) | 2.97941583 |
159 | microtubule depolymerization (GO:0007019) | 2.96641673 |
160 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.95379867 |
161 | regulation of muscle adaptation (GO:0043502) | 2.93025162 |
162 | establishment of protein localization to Golgi (GO:0072600) | 2.91776316 |
163 | establishment of apical/basal cell polarity (GO:0035089) | 2.89282170 |
164 | extracellular matrix disassembly (GO:0022617) | 2.88434373 |
165 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.87863053 |
166 | peptide cross-linking (GO:0018149) | 2.87569279 |
167 | glucocorticoid biosynthetic process (GO:0006704) | 2.86176868 |
168 | response to gonadotropin (GO:0034698) | 2.82160791 |
169 | homeostasis of number of cells within a tissue (GO:0048873) | 2.78841639 |
170 | phenol-containing compound catabolic process (GO:0019336) | 2.78771616 |
171 | toxin transport (GO:1901998) | 2.78606692 |
172 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.76826595 |
173 | regulation of cardioblast differentiation (GO:0051890) | 2.76161421 |
174 | acrosome reaction (GO:0007340) | 2.75517946 |
175 | wound healing, spreading of epidermal cells (GO:0035313) | 2.75362963 |
176 | zinc ion homeostasis (GO:0055069) | 2.75331410 |
177 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.74519728 |
178 | regulation of growth hormone secretion (GO:0060123) | 2.73580926 |
179 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.73194095 |
180 | peripheral nervous system axon ensheathment (GO:0032292) | 2.71580327 |
181 | myelination in peripheral nervous system (GO:0022011) | 2.71580327 |
182 | heart trabecula formation (GO:0060347) | 2.68397136 |
183 | blood vessel development (GO:0001568) | 2.68275749 |
184 | regulation of Rho protein signal transduction (GO:0035023) | 2.68258544 |
185 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 2.67851013 |
186 | protein localization to Golgi apparatus (GO:0034067) | 2.67698749 |
187 | folic acid transport (GO:0015884) | 2.67136196 |
188 | androgen biosynthetic process (GO:0006702) | 2.66749062 |
189 | peptidyl-proline hydroxylation (GO:0019511) | 2.62636162 |
190 | cellular response to gonadotropin stimulus (GO:0071371) | 2.62428338 |
191 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.60892100 |
192 | regulation of neuron migration (GO:2001222) | 2.60109093 |
193 | lung alveolus development (GO:0048286) | 2.59209752 |
194 | regulation of cardiac muscle tissue growth (GO:0055021) | 2.58758375 |
195 | cardiac ventricle formation (GO:0003211) | 2.58523182 |
196 | extracellular matrix assembly (GO:0085029) | 2.57410317 |
197 | mating behavior (GO:0007617) | 2.56308565 |
198 | definitive hemopoiesis (GO:0060216) | 2.53907501 |
199 | cardiac muscle tissue development (GO:0048738) | 2.53153746 |
200 | lung vasculature development (GO:0060426) | 2.53081835 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.22985110 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 6.99472461 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.63198347 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.34713832 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.02054068 |
6 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.65430910 |
7 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 4.61255112 |
8 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.44673011 |
9 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.00799881 |
10 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.72484905 |
11 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.42972327 |
12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.32569480 |
13 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.97840231 |
14 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.68038117 |
15 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.50120430 |
16 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.49519474 |
17 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.30429004 |
18 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.10554415 |
19 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.08409463 |
20 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.7156166 |
21 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.83167649 |
22 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.82287646 |
23 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.69814181 |
24 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.69652989 |
25 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.69442151 |
26 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.66240332 |
27 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.63294294 |
28 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.60217109 |
29 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.58809376 |
30 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.58809376 |
31 | GATA1_22025678_ChIP-Seq_K562_Human | 1.55293304 |
32 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.50357359 |
33 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.49616653 |
34 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.46112493 |
35 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.44099208 |
36 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.43828965 |
37 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.43277773 |
38 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.42844275 |
39 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.42744687 |
40 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.42495337 |
41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.41994839 |
42 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40638191 |
43 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.40638191 |
44 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.37053437 |
45 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.31001046 |
46 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.30705104 |
47 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.30651821 |
48 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.30116257 |
49 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.29980873 |
50 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.29657670 |
51 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.29425748 |
52 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.28642906 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.27854442 |
54 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.25410418 |
55 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.24482024 |
56 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.23808416 |
57 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.23542140 |
58 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.21543181 |
59 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.21487654 |
60 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.20593016 |
61 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.20354528 |
62 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.16966468 |
63 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.13201974 |
64 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.13031800 |
65 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.11741756 |
66 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.11676143 |
67 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.10003504 |
68 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.07054886 |
69 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.06884290 |
70 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.06325727 |
71 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.06223219 |
72 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.06093433 |
73 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.05367795 |
74 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.05367795 |
75 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.04776862 |
76 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.04674002 |
77 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.03599715 |
78 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.00154110 |
79 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.99548099 |
80 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.99147700 |
81 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.97371678 |
82 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.95705199 |
83 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.93918871 |
84 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93080494 |
85 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.92847334 |
86 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.92819845 |
87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91826723 |
88 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.89459041 |
89 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.89455780 |
90 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.89283084 |
91 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.88732289 |
92 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.88628835 |
93 | TP53_16413492_ChIP-PET_HCT116_Human | 0.88379753 |
94 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87981087 |
95 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.87238385 |
96 | FUS_26573619_Chip-Seq_HEK293_Human | 0.86430732 |
97 | AR_25329375_ChIP-Seq_VCAP_Human | 0.86100973 |
98 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.85696949 |
99 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85661263 |
100 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.85442603 |
101 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.85191285 |
102 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.85175296 |
103 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.85148620 |
104 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.84090268 |
105 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.83668417 |
106 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.83402284 |
107 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.81895972 |
108 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.80917778 |
109 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.80349867 |
110 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.79283010 |
111 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.77892809 |
112 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.77334667 |
113 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.76523399 |
114 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.75375550 |
115 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.71787679 |
116 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.71470579 |
117 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.69313238 |
118 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.68876090 |
119 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.68277350 |
120 | * RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.67904816 |
121 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.65732866 |
122 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.65652017 |
123 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.62876165 |
124 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.62829790 |
125 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.62603803 |
126 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.62603803 |
127 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.62125408 |
128 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.61630925 |
129 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.58924771 |
130 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.57746773 |
131 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.57442994 |
132 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.56826121 |
133 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.55369183 |
134 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.55297131 |
135 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.55029581 |
136 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.55021188 |
137 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.54571412 |
138 | AR_20517297_ChIP-Seq_VCAP_Human | 0.54313298 |
139 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.54255681 |
140 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.53811065 |
141 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.53783233 |
142 | CBP_21632823_ChIP-Seq_H3396_Human | 0.53197240 |
143 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.53099575 |
144 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.52687553 |
145 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.52221021 |
146 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.51879480 |
147 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.51649601 |
148 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.50034573 |
149 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.49836154 |
150 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.47889015 |
151 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.47720859 |
152 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.47417432 |
153 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.45137514 |
154 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.45101327 |
155 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.44798692 |
156 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.44650253 |
157 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.44294012 |
158 | GATA2_19941826_ChIP-Seq_K562_Human | 0.43574251 |
159 | GATA1_19941826_ChIP-Seq_K562_Human | 0.43426446 |
160 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.42975354 |
161 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.42545588 |
162 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.42434292 |
163 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.42293605 |
164 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.42206246 |
165 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.42105211 |
166 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.41798925 |
167 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.41364026 |
168 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.41170079 |
169 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.40689065 |
170 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.40489311 |
171 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.39591955 |
172 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.39325279 |
173 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.39303807 |
174 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.39070821 |
175 | NCOR_22424771_ChIP-Seq_293T_Human | 0.38968025 |
176 | * CTCF_27219007_Chip-Seq_Bcells_Human | 0.38962764 |
177 | * PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.38101874 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005275_abnormal_skin_tensile | 8.32407979 |
2 | MP0002139_abnormal_hepatobiliary_system | 8.26678808 |
3 | MP0005360_urolithiasis | 7.97513607 |
4 | MP0005085_abnormal_gallbladder_physiolo | 6.12304809 |
5 | MP0005365_abnormal_bile_salt | 5.90540956 |
6 | MP0005503_abnormal_tendon_morphology | 5.60789401 |
7 | MP0008875_abnormal_xenobiotic_pharmacok | 4.76516904 |
8 | MP0003252_abnormal_bile_duct | 3.82249300 |
9 | MP0003806_abnormal_nucleotide_metabolis | 3.77456567 |
10 | MP0004272_abnormal_basement_membrane | 3.47571849 |
11 | MP0010329_abnormal_lipoprotein_level | 3.43133031 |
12 | MP0001958_emphysema | 3.33952113 |
13 | MP0003195_calcinosis | 3.19912753 |
14 | MP0005332_abnormal_amino_acid | 3.11672878 |
15 | MP0009840_abnormal_foam_cell | 3.01722583 |
16 | MP0005083_abnormal_biliary_tract | 2.94675871 |
17 | MP0004019_abnormal_vitamin_homeostasis | 2.65742042 |
18 | MP0003191_abnormal_cellular_cholesterol | 2.52384184 |
19 | MP0001666_abnormal_nutrient_absorption | 2.43865206 |
20 | MP0002138_abnormal_hepatobiliary_system | 2.36959607 |
21 | MP0003279_aneurysm | 2.16001140 |
22 | MP0002060_abnormal_skin_morphology | 2.09596233 |
23 | MP0003122_maternal_imprinting | 2.07175023 |
24 | MP0000609_abnormal_liver_physiology | 2.05644327 |
25 | MP0002118_abnormal_lipid_homeostasis | 2.04675671 |
26 | MP0005410_abnormal_fertilization | 2.02048724 |
27 | MP0003567_abnormal_fetal_cardiomyocyte | 2.01955280 |
28 | MP0008438_abnormal_cutaneous_collagen | 10.9233769 |
29 | MP0004858_abnormal_nervous_system | 1.89402386 |
30 | MP0008004_abnormal_stomach_pH | 1.77879889 |
31 | MP0005319_abnormal_enzyme/_coenzyme | 1.77280249 |
32 | MP0003868_abnormal_feces_composition | 1.69618777 |
33 | MP0002108_abnormal_muscle_morphology | 1.67357199 |
34 | MP0001764_abnormal_homeostasis | 1.66496275 |
35 | MP0005171_absent_coat_pigmentation | 1.66174286 |
36 | MP0009643_abnormal_urine_homeostasis | 1.59843572 |
37 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.59790909 |
38 | MP0003011_delayed_dark_adaptation | 1.48025315 |
39 | MP0005508_abnormal_skeleton_morphology | 1.47703529 |
40 | MP0010030_abnormal_orbit_morphology | 1.47545834 |
41 | MP0002295_abnormal_pulmonary_circulatio | 1.44546508 |
42 | MP0005451_abnormal_body_composition | 1.42470702 |
43 | MP0002282_abnormal_trachea_morphology | 1.36601709 |
44 | MP0005636_abnormal_mineral_homeostasis | 1.33158843 |
45 | MP0003385_abnormal_body_wall | 1.30865934 |
46 | MP0005647_abnormal_sex_gland | 1.24961640 |
47 | MP0003941_abnormal_skin_development | 1.24254588 |
48 | MP0003186_abnormal_redox_activity | 1.22115210 |
49 | MP0009697_abnormal_copulation | 1.21953989 |
50 | MP0001501_abnormal_sleep_pattern | 1.17985299 |
51 | MP0010386_abnormal_urinary_bladder | 1.15216620 |
52 | MP0001348_abnormal_lacrimal_gland | 1.11327351 |
53 | MP0005257_abnormal_intraocular_pressure | 1.11209265 |
54 | MP0002876_abnormal_thyroid_physiology | 1.08424099 |
55 | MP0000598_abnormal_liver_morphology | 1.07794785 |
56 | MP0003656_abnormal_erythrocyte_physiolo | 1.07313572 |
57 | MP0004043_abnormal_pH_regulation | 1.07229278 |
58 | MP0000604_amyloidosis | 1.07054239 |
59 | MP0005084_abnormal_gallbladder_morpholo | 1.04289605 |
60 | MP0005164_abnormal_response_to | 1.02774207 |
61 | MP0001879_abnormal_lymphatic_vessel | 1.01775500 |
62 | MP0009764_decreased_sensitivity_to | 0.99390172 |
63 | MP0000751_myopathy | 0.99301749 |
64 | MP0004264_abnormal_extraembryonic_tissu | 0.95125440 |
65 | MP0005409_darkened_coat_color | 0.94032915 |
66 | MP0001756_abnormal_urination | 0.90912869 |
67 | MP0009642_abnormal_blood_homeostasis | 0.90182039 |
68 | MP0002133_abnormal_respiratory_system | 0.89609496 |
69 | MP0005388_respiratory_system_phenotype | 0.89609496 |
70 | MP0003942_abnormal_urinary_system | 0.89456206 |
71 | MP0009763_increased_sensitivity_to | 0.88491333 |
72 | MP0005390_skeleton_phenotype | 0.86837130 |
73 | MP0006138_congestive_heart_failure | 0.85771534 |
74 | MP0010368_abnormal_lymphatic_system | 0.84928574 |
75 | MP0003300_gastrointestinal_ulcer | 0.84695624 |
76 | MP0008469_abnormal_protein_level | 0.84455913 |
77 | MP0002078_abnormal_glucose_homeostasis | 0.82839840 |
78 | MP0003115_abnormal_respiratory_system | 0.81545639 |
79 | MP0002254_reproductive_system_inflammat | 0.81384906 |
80 | MP0003705_abnormal_hypodermis_morpholog | 0.81282009 |
81 | MP0006036_abnormal_mitochondrial_physio | 0.81187655 |
82 | MP0005220_abnormal_exocrine_pancreas | 0.80831331 |
83 | MP0005535_abnormal_body_temperature | 0.80584735 |
84 | MP0005408_hypopigmentation | 0.79933056 |
85 | MP0000750_abnormal_muscle_regeneration | 0.79783233 |
86 | MP0003566_abnormal_cell_adhesion | 0.79157909 |
87 | MP0002896_abnormal_bone_mineralization | 0.78644580 |
88 | MP0002136_abnormal_kidney_physiology | 0.77537774 |
89 | MP0005376_homeostasis/metabolism_phenot | 0.75654756 |
90 | MP0002971_abnormal_brown_adipose | 0.73823018 |
91 | MP0001661_extended_life_span | 0.73540073 |
92 | MP0009765_abnormal_xenobiotic_induced | 0.73485053 |
93 | MP0005369_muscle_phenotype | 0.72489194 |
94 | MP0000462_abnormal_digestive_system | 0.72220170 |
95 | MP0003632_abnormal_nervous_system | 0.70422119 |
96 | MP0002106_abnormal_muscle_physiology | 0.68915487 |
97 | MP0001243_abnormal_dermal_layer | 0.68504956 |
98 | MP0001765_abnormal_ion_homeostasis | 0.68190710 |
99 | MP0001177_atelectasis | 0.67919470 |
100 | MP0000767_abnormal_smooth_muscle | 0.67683539 |
101 | MP0003698_abnormal_male_reproductive | 0.66644392 |
102 | MP0009780_abnormal_chondrocyte_physiolo | 0.66578267 |
103 | MP0003638_abnormal_response/metabolism_ | 0.65857125 |
104 | MP0003329_amyloid_beta_deposits | 0.64462180 |
105 | MP0002928_abnormal_bile_duct | 0.64402828 |
106 | MP0000639_abnormal_adrenal_gland | 0.64401811 |
107 | MP0005377_hearing/vestibular/ear_phenot | 0.62205671 |
108 | MP0003878_abnormal_ear_physiology | 0.62205671 |
109 | MP0001614_abnormal_blood_vessel | 0.61615025 |
110 | MP0004130_abnormal_muscle_cell | 0.61313486 |
111 | MP0005670_abnormal_white_adipose | 0.61236758 |
112 | MP0002115_abnormal_skeleton_extremities | 0.61150316 |
113 | MP0000428_abnormal_craniofacial_morphol | 0.61094419 |
114 | MP0005334_abnormal_fat_pad | 0.60212138 |
115 | MP0003690_abnormal_glial_cell | 0.59768192 |
116 | MP0002998_abnormal_bone_remodeling | 0.59668117 |
117 | MP0003091_abnormal_cell_migration | 0.58100509 |
118 | MP0005395_other_phenotype | 0.57819568 |
119 | MP0004134_abnormal_chest_morphology | 0.55340012 |
120 | MP0004947_skin_inflammation | 0.54393404 |
121 | MP0005023_abnormal_wound_healing | 0.54319510 |
122 | MP0005448_abnormal_energy_balance | 0.54009423 |
123 | MP0005076_abnormal_cell_differentiation | 0.53785372 |
124 | MP0003879_abnormal_hair_cell | 0.53365017 |
125 | MP0005623_abnormal_meninges_morphology | 0.52872018 |
126 | MP0003718_maternal_effect | 0.52225699 |
127 | MP0001175_abnormal_lung_morphology | 0.52159807 |
128 | MP0005266_abnormal_metabolism | 0.52043417 |
129 | MP0002822_catalepsy | 0.50485351 |
130 | MP0010771_integument_phenotype | 0.50191232 |
131 | MP0009053_abnormal_anal_canal | 0.48772214 |
132 | MP0003950_abnormal_plasma_membrane | 0.48546367 |
133 | MP0005666_abnormal_adipose_tissue | 0.47843693 |
134 | MP0003953_abnormal_hormone_level | 0.47100343 |
135 | MP0000163_abnormal_cartilage_morphology | 0.47068916 |
136 | MP0000534_abnormal_ureter_morphology | 0.46853851 |
137 | MP0000230_abnormal_systemic_arterial | 0.46527547 |
138 | MP0000049_abnormal_middle_ear | 0.46364795 |
139 | MP0006035_abnormal_mitochondrial_morpho | 0.46119940 |
140 | MP0003724_increased_susceptibility_to | 0.46016787 |
141 | MP0002933_joint_inflammation | 0.45964419 |
142 | MP0008874_decreased_physiological_sensi | 0.45866549 |
143 | MP0002233_abnormal_nose_morphology | 0.45617082 |
144 | MP0002837_dystrophic_cardiac_calcinosis | 0.45458343 |
145 | MP0004381_abnormal_hair_follicle | 0.45449746 |
146 | MP0000538_abnormal_urinary_bladder | 0.45028907 |
147 | MP0004782_abnormal_surfactant_physiolog | 0.44661527 |
148 | MP0000566_synostosis | 0.44548499 |
149 | MP0009672_abnormal_birth_weight | 0.42775575 |
150 | MP0002796_impaired_skin_barrier | 0.42746044 |
151 | MP0009384_cardiac_valve_regurgitation | 0.42205075 |
152 | MP0003943_abnormal_hepatobiliary_system | 0.40413429 |
153 | MP0005464_abnormal_platelet_physiology | 0.40200963 |
154 | MP0000013_abnormal_adipose_tissue | 0.39893135 |
155 | MP0003075_altered_response_to | 0.39447959 |
156 | MP0003436_decreased_susceptibility_to | 0.38843061 |
157 | MP0002127_abnormal_cardiovascular_syste | 0.38749975 |
158 | MP0001929_abnormal_gametogenesis | 0.38619123 |
159 | MP0010630_abnormal_cardiac_muscle | 0.38489426 |
160 | MP0002932_abnormal_joint_morphology | 0.37893884 |
161 | MP0002102_abnormal_ear_morphology | 0.36486483 |
162 | MP0009250_abnormal_appendicular_skeleto | 0.36390539 |
163 | MP0004883_abnormal_blood_vessel | 0.35682511 |
164 | MP0005166_decreased_susceptibility_to | 0.35552256 |
165 | MP0002168_other_aberrant_phenotype | 0.34795187 |
166 | MP0008873_increased_physiological_sensi | 0.33952093 |
167 | MP0002135_abnormal_kidney_morphology | 0.33711611 |
168 | MP0009115_abnormal_fat_cell | 0.31610789 |
169 | MP0008872_abnormal_physiological_respon | 0.30599061 |
170 | MP0004147_increased_porphyrin_level | 0.29534708 |
171 | MP0005551_abnormal_eye_electrophysiolog | 0.29118145 |
172 | MP0005058_abnormal_lysosome_morphology | 0.28357344 |
173 | MP0001881_abnormal_mammary_gland | 0.27396212 |
174 | MP0003959_abnormal_lean_body | 0.27053519 |
175 | MP0001944_abnormal_pancreas_morphology | 0.26787417 |
176 | MP0000579_abnormal_nail_morphology | 0.26781512 |
177 | MP0005595_abnormal_vascular_smooth | 0.25359667 |
178 | MP0001845_abnormal_inflammatory_respons | 0.24554064 |
179 | MP0002970_abnormal_white_adipose | 0.24128812 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Premature rupture of membranes (HP:0001788) | 8.86982179 |
2 | Aortic dissection (HP:0002647) | 7.52800141 |
3 | Intrahepatic cholestasis (HP:0001406) | 6.95854419 |
4 | Deep venous thrombosis (HP:0002625) | 6.86398967 |
5 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 6.80671792 |
6 | Protrusio acetabuli (HP:0003179) | 6.52464284 |
7 | Soft skin (HP:0000977) | 6.36182099 |
8 | Prolonged partial thromboplastin time (HP:0003645) | 6.22349821 |
9 | Xanthomatosis (HP:0000991) | 5.96906370 |
10 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 5.78699373 |
11 | Cerebral aneurysm (HP:0004944) | 5.58126834 |
12 | Atrophic scars (HP:0001075) | 5.54901746 |
13 | Hypobetalipoproteinemia (HP:0003563) | 5.35638009 |
14 | Bladder diverticulum (HP:0000015) | 5.35074816 |
15 | Fragile skin (HP:0001030) | 5.33209644 |
16 | Peritonitis (HP:0002586) | 5.00800532 |
17 | Complement deficiency (HP:0004431) | 4.98925418 |
18 | Hyperlipoproteinemia (HP:0010980) | 4.84287480 |
19 | Hyperglycinemia (HP:0002154) | 4.75091749 |
20 | Renovascular hypertension (HP:0100817) | 4.70970035 |
21 | Joint hemorrhage (HP:0005261) | 4.66661989 |
22 | Ketosis (HP:0001946) | 4.61684569 |
23 | Alopecia of scalp (HP:0002293) | 4.47767043 |
24 | Hyperammonemia (HP:0001987) | 4.44785807 |
25 | Hyperglycinuria (HP:0003108) | 4.43793125 |
26 | Aortic aneurysm (HP:0004942) | 4.41859181 |
27 | Abnormality of dentin (HP:0010299) | 4.39897687 |
28 | Abnormality of serine family amino acid metabolism (HP:0010894) | 4.35046144 |
29 | Abnormality of glycine metabolism (HP:0010895) | 4.35046144 |
30 | Hypolipoproteinemia (HP:0010981) | 4.31438818 |
31 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.30170279 |
32 | Abnormality of the common coagulation pathway (HP:0010990) | 4.29722412 |
33 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.15594335 |
34 | Striae distensae (HP:0001065) | 4.14986565 |
35 | Abnormal delivery (HP:0001787) | 4.12254681 |
36 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.08311870 |
37 | Hypoalphalipoproteinemia (HP:0003233) | 4.06255021 |
38 | Dilatation of the ascending aorta (HP:0005111) | 4.05091474 |
39 | Blue sclerae (HP:0000592) | 3.99564510 |
40 | Delayed CNS myelination (HP:0002188) | 3.92537266 |
41 | Gout (HP:0001997) | 3.88535681 |
42 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 3.87639210 |
43 | Fat malabsorption (HP:0002630) | 3.86218031 |
44 | Hypoglycemic coma (HP:0001325) | 3.81861920 |
45 | Abnormality of methionine metabolism (HP:0010901) | 3.75588787 |
46 | Epidermoid cyst (HP:0200040) | 3.73602256 |
47 | Ketoacidosis (HP:0001993) | 3.64795497 |
48 | Abnormality of the intrinsic pathway (HP:0010989) | 3.59054163 |
49 | Conjugated hyperbilirubinemia (HP:0002908) | 3.59008680 |
50 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.58140465 |
51 | Abnormality of complement system (HP:0005339) | 3.54257586 |
52 | Gastrointestinal infarctions (HP:0005244) | 3.47977142 |
53 | Mitral valve prolapse (HP:0001634) | 3.47623767 |
54 | Hyperextensible skin (HP:0000974) | 3.40815058 |
55 | Osteoarthritis (HP:0002758) | 3.39407680 |
56 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 3.34966767 |
57 | Osteolytic defects of the hand bones (HP:0009699) | 3.34966767 |
58 | Abnormality of purine metabolism (HP:0004352) | 3.34343420 |
59 | Abnormality of nucleobase metabolism (HP:0010932) | 3.32136926 |
60 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.27723938 |
61 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.26104962 |
62 | Osteomalacia (HP:0002749) | 3.21320461 |
63 | Vascular tortuosity (HP:0004948) | 3.17100881 |
64 | Hyperbilirubinemia (HP:0002904) | 3.16560723 |
65 | Hypercholesterolemia (HP:0003124) | 3.15298668 |
66 | Keratoconus (HP:0000563) | 3.12811537 |
67 | Increased corneal curvature (HP:0100692) | 3.12811537 |
68 | Shallow orbits (HP:0000586) | 3.08905076 |
69 | Abnormality of serum amino acid levels (HP:0003112) | 3.07536419 |
70 | Biconcave vertebral bodies (HP:0004586) | 3.04439174 |
71 | Hepatocellular carcinoma (HP:0001402) | 3.03103649 |
72 | Metabolic acidosis (HP:0001942) | 3.01236435 |
73 | Abnormality of the ischium (HP:0003174) | 2.97023327 |
74 | Vertebral compression fractures (HP:0002953) | 2.96203719 |
75 | Thin bony cortex (HP:0002753) | 2.94226061 |
76 | Vascular calcification (HP:0004934) | 2.93558864 |
77 | Fibular hypoplasia (HP:0003038) | 2.87802729 |
78 | Steatorrhea (HP:0002570) | 2.86839290 |
79 | Hypochromic microcytic anemia (HP:0004840) | 2.85333754 |
80 | Spontaneous abortion (HP:0005268) | 2.83936907 |
81 | Dicarboxylic aciduria (HP:0003215) | 2.82080786 |
82 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.82080786 |
83 | Aneurysm (HP:0002617) | 2.80970956 |
84 | Ectopia lentis (HP:0001083) | 2.78994927 |
85 | Narrow nasal bridge (HP:0000446) | 2.77378346 |
86 | Joint laxity (HP:0001388) | 2.73506120 |
87 | Genu recurvatum (HP:0002816) | 2.73132064 |
88 | Lethargy (HP:0001254) | 2.70640125 |
89 | Abnormality of the acetabulum (HP:0003170) | 2.70592311 |
90 | Venous insufficiency (HP:0005293) | 2.67833599 |
91 | Wormian bones (HP:0002645) | 2.64274819 |
92 | Enlarged kidneys (HP:0000105) | 2.62475112 |
93 | Hyperuricemia (HP:0002149) | 2.61623987 |
94 | Increased purine levels (HP:0004368) | 2.61623987 |
95 | Cardiovascular calcification (HP:0011915) | 2.59277194 |
96 | Neonatal onset (HP:0003623) | 2.55425123 |
97 | Generalized aminoaciduria (HP:0002909) | 2.52912954 |
98 | Thoracolumbar scoliosis (HP:0002944) | 2.52455301 |
99 | Proximal tubulopathy (HP:0000114) | 2.51015449 |
100 | Patent foramen ovale (HP:0001655) | 2.50502075 |
101 | Hypoglycemic seizures (HP:0002173) | 2.48195311 |
102 | Periodontitis (HP:0000704) | 2.47160496 |
103 | Systemic lupus erythematosus (HP:0002725) | 2.46194242 |
104 | Malnutrition (HP:0004395) | 2.44911497 |
105 | Broad metatarsal (HP:0001783) | 2.43176594 |
106 | Late onset (HP:0003584) | 2.41499084 |
107 | Cerebral edema (HP:0002181) | 2.41405021 |
108 | Myocardial infarction (HP:0001658) | 2.41181050 |
109 | Wide anterior fontanel (HP:0000260) | 2.39965178 |
110 | Irritability (HP:0000737) | 2.38257647 |
111 | Vitreoretinal degeneration (HP:0000655) | 2.36243593 |
112 | Arterial tortuosity (HP:0005116) | 2.35662438 |
113 | Hypoplasia of the iris (HP:0007676) | 2.35295454 |
114 | Alkalosis (HP:0001948) | 2.33423780 |
115 | Rickets (HP:0002748) | 2.32532803 |
116 | Venous abnormality (HP:0002624) | 2.31908726 |
117 | Broad ribs (HP:0000885) | 2.31463789 |
118 | Vomiting (HP:0002013) | 2.31012740 |
119 | Skin nodule (HP:0200036) | 2.29223640 |
120 | Sensorimotor neuropathy (HP:0007141) | 2.25668808 |
121 | Bowel diverticulosis (HP:0005222) | 2.25474192 |
122 | Spastic diplegia (HP:0001264) | 2.25339855 |
123 | Mitral stenosis (HP:0001718) | 2.24912038 |
124 | Glycosuria (HP:0003076) | 2.24769011 |
125 | Abnormality of urine glucose concentration (HP:0011016) | 2.24769011 |
126 | Pancreatitis (HP:0001733) | 2.21704703 |
127 | Abnormal gallbladder morphology (HP:0012437) | 2.21148336 |
128 | Right ventricular cardiomyopathy (HP:0011663) | 2.20958690 |
129 | Inguinal hernia (HP:0000023) | 2.20033089 |
130 | Cholelithiasis (HP:0001081) | 2.19653749 |
131 | Trismus (HP:0000211) | 2.19472896 |
132 | Sprengel anomaly (HP:0000912) | 2.19156000 |
133 | Amyloidosis (HP:0011034) | 2.14777200 |
134 | Glomerulonephritis (HP:0000099) | 2.13535391 |
135 | Hypophosphatemic rickets (HP:0004912) | 2.11509599 |
136 | Short tibia (HP:0005736) | 2.11330173 |
137 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.09562302 |
138 | Acanthocytosis (HP:0001927) | 2.08722585 |
139 | Thin ribs (HP:0000883) | 2.07266420 |
140 | Abnormal gallbladder physiology (HP:0012438) | 2.07147701 |
141 | Cholecystitis (HP:0001082) | 2.07147701 |
142 | Menorrhagia (HP:0000132) | 2.06384049 |
143 | Opisthotonus (HP:0002179) | 2.05170694 |
144 | Gingival bleeding (HP:0000225) | 2.04761065 |
145 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.04511730 |
146 | Thrombophlebitis (HP:0004418) | 2.03785860 |
147 | Gingivitis (HP:0000230) | 2.03728747 |
148 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.02572369 |
149 | Redundant skin (HP:0001582) | 2.02001455 |
150 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.99048908 |
151 | Ulnar bowing (HP:0003031) | 1.97743143 |
152 | Breech presentation (HP:0001623) | 1.97676538 |
153 | Abnormality of proline metabolism (HP:0010907) | 1.97302793 |
154 | Hydroxyprolinuria (HP:0003080) | 1.97302793 |
155 | Thin skin (HP:0000963) | 1.95942972 |
156 | Esophageal varix (HP:0002040) | 1.95775034 |
157 | Nephrolithiasis (HP:0000787) | 1.94768141 |
158 | Bifid tongue (HP:0010297) | 1.94601192 |
159 | Short 5th finger (HP:0009237) | 1.94156774 |
160 | Tubulointerstitial nephritis (HP:0001970) | 1.93866197 |
161 | Abnormality of the aortic arch (HP:0012303) | 1.92505981 |
162 | Confusion (HP:0001289) | 1.90522252 |
163 | Multifactorial inheritance (HP:0001426) | 1.89774313 |
164 | Infantile muscular hypotonia (HP:0008947) | 1.89489703 |
165 | Brushfield spots (HP:0001088) | 1.87441723 |
166 | Hypoplastic ischia (HP:0003175) | 1.84667917 |
167 | Absent frontal sinuses (HP:0002688) | 1.83112276 |
168 | Asymmetric septal hypertrophy (HP:0001670) | 1.82739831 |
169 | Abnormality of the gallbladder (HP:0005264) | 1.82662426 |
170 | Hemorrhage of the eye (HP:0011885) | 1.82363909 |
171 | Short middle phalanx of the 5th finger (HP:0004220) | 1.82026013 |
172 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.81954355 |
173 | Elevated hepatic transaminases (HP:0002910) | 1.81635819 |
174 | Oligomenorrhea (HP:0000876) | 1.81068436 |
175 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.80929719 |
176 | Neonatal short-limb short stature (HP:0008921) | 1.79630426 |
177 | Symptomatic seizures (HP:0011145) | 1.77554946 |
178 | Retinal atrophy (HP:0001105) | 1.74913869 |
179 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.74822593 |
180 | Pulmonary artery stenosis (HP:0004415) | 1.74340412 |
181 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.73655745 |
182 | Aortic regurgitation (HP:0001659) | 1.70901545 |
183 | Abnormality of the peritoneum (HP:0002585) | 1.70801952 |
184 | Coxa vara (HP:0002812) | 1.69311350 |
185 | Chronic hepatic failure (HP:0100626) | 1.67222014 |
186 | Abnormality of the anterior chamber (HP:0000593) | 1.66377881 |
187 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.65236657 |
188 | Premature loss of primary teeth (HP:0006323) | 1.64255614 |
189 | Overgrowth (HP:0001548) | 1.64235026 |
190 | Follicular hyperkeratosis (HP:0007502) | 1.63421847 |
191 | Coronal craniosynostosis (HP:0004440) | 1.60332348 |
192 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.57109182 |
193 | Flat cornea (HP:0007720) | 1.56786001 |
194 | Abnormality of molar (HP:0011077) | 1.56029103 |
195 | Abnormality of molar morphology (HP:0011070) | 1.56029103 |
196 | Cervical subluxation (HP:0003308) | 1.55938888 |
197 | Micromelia (HP:0002983) | 1.55472498 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PLK4 | 7.51617562 |
2 | BCKDK | 7.05140409 |
3 | SIK1 | 4.25031305 |
4 | FGFR4 | 4.17744244 |
5 | ERN1 | 3.81393437 |
6 | CDC42BPA | 3.46285051 |
7 | ERBB4 | 3.20957758 |
8 | PDGFRA | 2.97547804 |
9 | TAOK3 | 2.92830393 |
10 | INSRR | 2.80797777 |
11 | WNK4 | 2.69582302 |
12 | WNK3 | 2.67580238 |
13 | TYRO3 | 2.45603408 |
14 | MST1R | 2.43996943 |
15 | PIK3CG | 2.22530362 |
16 | OXSR1 | 2.12488273 |
17 | MAP3K6 | 2.00302463 |
18 | PRPF4B | 1.98561564 |
19 | MAP4K2 | 1.94930403 |
20 | MAP2K4 | 1.86645231 |
21 | MAPK11 | 1.83136052 |
22 | PLK2 | 1.78842149 |
23 | CLK1 | 1.58427022 |
24 | BRD4 | 1.57663331 |
25 | CAMK1G | 1.51494118 |
26 | PKN2 | 1.51474558 |
27 | DAPK2 | 1.48102518 |
28 | TYK2 | 1.45241456 |
29 | FLT3 | 1.36782683 |
30 | MAP3K7 | 1.32195607 |
31 | GRK6 | 1.31537050 |
32 | TRIB3 | 1.28971085 |
33 | PDGFRB | 1.28686474 |
34 | PRKAA2 | 1.28489847 |
35 | CASK | 1.27780821 |
36 | MAPK15 | 1.27501086 |
37 | LATS1 | 1.27129851 |
38 | PTK6 | 1.24693825 |
39 | NEK6 | 1.22100131 |
40 | DDR2 | 1.20261422 |
41 | NEK9 | 1.18701346 |
42 | SGK223 | 1.18554491 |
43 | SGK494 | 1.18554491 |
44 | MAPKAPK5 | 1.18404101 |
45 | PDK2 | 1.17602700 |
46 | STK38L | 1.16071896 |
47 | NLK | 1.15752662 |
48 | FGFR2 | 1.12017490 |
49 | JAK2 | 1.11509067 |
50 | EPHB2 | 1.10259126 |
51 | SGK2 | 1.09224934 |
52 | STK38 | 1.08618387 |
53 | NEK2 | 1.06821261 |
54 | PRKCZ | 1.05864113 |
55 | MET | 1.05037586 |
56 | NTRK1 | 1.04333249 |
57 | MAPK4 | 1.03570640 |
58 | ABL2 | 1.03334216 |
59 | LATS2 | 1.02047421 |
60 | SGK3 | 1.01993869 |
61 | PINK1 | 0.96823196 |
62 | KDR | 0.94344993 |
63 | TIE1 | 0.93820360 |
64 | RPS6KA5 | 0.90618847 |
65 | RIPK1 | 0.88720971 |
66 | NTRK2 | 0.88489695 |
67 | PNCK | 0.86021852 |
68 | MAPK12 | 0.85982540 |
69 | EPHB1 | 0.85912834 |
70 | PRKACG | 0.84826961 |
71 | JAK1 | 0.84687975 |
72 | NME1 | 0.84485594 |
73 | GRK1 | 0.83894772 |
74 | STK39 | 0.83890403 |
75 | PTK2 | 0.83671990 |
76 | ERBB2 | 0.82450012 |
77 | GSK3A | 0.81498000 |
78 | FRK | 0.81148842 |
79 | PRKAA1 | 0.80744958 |
80 | EPHA4 | 0.78189804 |
81 | CAMK2G | 0.77070319 |
82 | MAP3K10 | 0.75956548 |
83 | DYRK1B | 0.74818528 |
84 | FER | 0.73904634 |
85 | PRKCG | 0.70622887 |
86 | PRKD3 | 0.66674283 |
87 | MAPK7 | 0.64083877 |
88 | MAP2K2 | 0.61754391 |
89 | PAK2 | 0.61657132 |
90 | TAOK2 | 0.61027981 |
91 | DAPK3 | 0.59636484 |
92 | MAP3K12 | 0.58755707 |
93 | CSNK1G1 | 0.56273457 |
94 | MAPK13 | 0.56006979 |
95 | MINK1 | 0.55378511 |
96 | PRKG2 | 0.54727639 |
97 | EEF2K | 0.54482012 |
98 | ROCK1 | 0.54350936 |
99 | MAP3K14 | 0.54244225 |
100 | PKN1 | 0.52879151 |
101 | EPHA3 | 0.52395554 |
102 | TBK1 | 0.51470426 |
103 | MAP2K3 | 0.51336455 |
104 | PDK3 | 0.50926267 |
105 | PDK4 | 0.50926267 |
106 | CSK | 0.49865950 |
107 | MAP2K6 | 0.49003852 |
108 | PDPK1 | 0.47783944 |
109 | MAP2K1 | 0.47449167 |
110 | CAMK4 | 0.47232585 |
111 | JAK3 | 0.46084160 |
112 | MARK2 | 0.46008424 |
113 | TGFBR2 | 0.45673451 |
114 | MAPK1 | 0.44049777 |
115 | CAMK1 | 0.44001570 |
116 | IGF1R | 0.42406054 |
117 | DYRK2 | 0.40326277 |
118 | PRKCQ | 0.39525430 |
119 | MAP3K3 | 0.39462374 |
120 | PRKCA | 0.39056038 |
121 | ADRBK2 | 0.37388478 |
122 | SCYL2 | 0.35754550 |
123 | RPS6KA2 | 0.35173723 |
124 | TESK1 | 0.34969739 |
125 | MAP3K5 | 0.34004994 |
126 | FGFR3 | 0.33661530 |
127 | CDK6 | 0.33532328 |
128 | CDK12 | 0.33291969 |
129 | PIK3CA | 0.33222065 |
130 | CSF1R | 0.33177337 |
131 | PRKACA | 0.31545128 |
132 | CSNK1A1L | 0.30704812 |
133 | CAMK1D | 0.29616659 |
134 | PRKACB | 0.29167106 |
135 | CSNK1G3 | 0.28507001 |
136 | STK16 | 0.28479223 |
137 | RPS6KA3 | 0.27906368 |
138 | PDK1 | 0.27831596 |
139 | PRKCB | 0.27726165 |
140 | CAMK2A | 0.26471989 |
141 | MAPK3 | 0.26438426 |
142 | IKBKE | 0.26206077 |
143 | MTOR | 0.26190209 |
144 | PTK2B | 0.25654023 |
145 | RET | 0.25514437 |
146 | MYLK | 0.24615702 |
147 | PRKG1 | 0.23163029 |
148 | ICK | 0.22546205 |
149 | PRKCH | 0.22475062 |
150 | SIK2 | 0.22435862 |
151 | AKT3 | 0.22435305 |
152 | EGFR | 0.22349970 |
153 | ADRBK1 | 0.22164515 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.37366710 |
2 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.33042515 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.31521543 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.23911184 |
5 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.19972037 |
6 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.98792442 |
7 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.88338696 |
8 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.80010934 |
9 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.70402554 |
10 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.65172814 |
11 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.64050656 |
12 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.62264979 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.62084382 |
14 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.61524672 |
15 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.59496577 |
16 | Amoebiasis_Homo sapiens_hsa05146 | 2.39075349 |
17 | Peroxisome_Homo sapiens_hsa04146 | 2.24528876 |
18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.22254821 |
19 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.20317673 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.11855626 |
21 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.02847671 |
22 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.96742086 |
23 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.90250644 |
24 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.86745957 |
25 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.75029621 |
26 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.74819881 |
27 | Histidine metabolism_Homo sapiens_hsa00340 | 1.74187388 |
28 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.72218896 |
29 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.67126172 |
30 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.65673230 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.63693345 |
32 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.62390841 |
33 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.62305164 |
34 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.56830515 |
35 | Bile secretion_Homo sapiens_hsa04976 | 1.56401895 |
36 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.55884696 |
37 | Focal adhesion_Homo sapiens_hsa04510 | 1.54014625 |
38 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.53734432 |
39 | Retinol metabolism_Homo sapiens_hsa00830 | 1.53187171 |
40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.52502154 |
41 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.46300908 |
42 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.43686911 |
43 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.40199877 |
44 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.37994393 |
45 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.35531130 |
46 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.35071676 |
47 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.34165699 |
48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.33286585 |
49 | Other glycan degradation_Homo sapiens_hsa00511 | 1.30904973 |
50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.29649265 |
51 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.29316793 |
52 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.28085278 |
53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.24183585 |
54 | Nicotine addiction_Homo sapiens_hsa05033 | 1.23474545 |
55 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.22310010 |
56 | Carbon metabolism_Homo sapiens_hsa01200 | 1.19843733 |
57 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.18544119 |
58 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.18005340 |
59 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.17892660 |
60 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.16602424 |
61 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.15782913 |
62 | ABC transporters_Homo sapiens_hsa02010 | 1.12563796 |
63 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.12055583 |
64 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.10732238 |
65 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.09972163 |
66 | Gap junction_Homo sapiens_hsa04540 | 1.09676107 |
67 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.07250035 |
68 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.05849301 |
69 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.03584114 |
70 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.02732736 |
71 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.01759655 |
72 | Lysine degradation_Homo sapiens_hsa00310 | 0.98742844 |
73 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.98646991 |
74 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.97629927 |
75 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.94267761 |
76 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.91632930 |
77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.90833282 |
78 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.87514198 |
79 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87120986 |
80 | Cocaine addiction_Homo sapiens_hsa05030 | 0.87108869 |
81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.87025461 |
82 | Platelet activation_Homo sapiens_hsa04611 | 0.86207657 |
83 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.84654709 |
84 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.82766031 |
85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.82482392 |
86 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.72920775 |
87 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70163287 |
88 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.70023099 |
89 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.69930270 |
90 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.69355811 |
91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.68093332 |
92 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.67984598 |
93 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.67518056 |
94 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.66871570 |
95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.64491577 |
96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64355086 |
97 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.63771628 |
98 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.63181980 |
99 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.61086476 |
100 | Renin secretion_Homo sapiens_hsa04924 | 0.58363361 |
101 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.57219481 |
102 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56674192 |
103 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.53632259 |
104 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.52236222 |
105 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50146649 |
106 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.49645128 |
107 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.47135014 |
108 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.46813549 |
109 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.45579784 |
110 | Adherens junction_Homo sapiens_hsa04520 | 0.45013642 |
111 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.43690803 |
112 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43548054 |
113 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.41943731 |
114 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.41887192 |
115 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.40758110 |
116 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.40455938 |
117 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.39504944 |
118 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.38221903 |
119 | Axon guidance_Homo sapiens_hsa04360 | 0.37500515 |
120 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.36449427 |
121 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.35658353 |
122 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.34951348 |
123 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.33764769 |
124 | Endocytosis_Homo sapiens_hsa04144 | 0.33275052 |
125 | Alcoholism_Homo sapiens_hsa05034 | 0.33124859 |
126 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.32934026 |
127 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.32831569 |
128 | Prion diseases_Homo sapiens_hsa05020 | 0.32310775 |
129 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.30775811 |
130 | Galactose metabolism_Homo sapiens_hsa00052 | 0.26492005 |
131 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.24110067 |
132 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23395036 |
133 | Insulin resistance_Homo sapiens_hsa04931 | 0.21023710 |
134 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.20233440 |
135 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.13162718 |
136 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.12340448 |
137 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.06438634 |
138 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01620177 |
139 | Bladder cancer_Homo sapiens_hsa05219 | -0.2177423 |
140 | Phototransduction_Homo sapiens_hsa04744 | -0.2146351 |
141 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.2137234 |
142 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.2131472 |
143 | Hepatitis C_Homo sapiens_hsa05160 | -0.1967217 |
144 | Mineral absorption_Homo sapiens_hsa04978 | -0.1902342 |
145 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1671578 |
146 | Collecting duct acid secretion_Homo sapiens_hsa04966 | -0.1599262 |
147 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.1497427 |
148 | Oxidative phosphorylation_Homo sapiens_hsa00190 | -0.1462477 |
149 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.1360445 |
150 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1314529 |
151 | Protein digestion and absorption_Homo sapiens_hsa04974 | -0.1293423 |
152 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.1118153 |
153 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1087154 |
154 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.0995470 |
155 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.0769376 |
156 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0662556 |
157 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0545598 |
158 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0372963 |